Journal articles on the topic 'Cd40lg-/- mouse'
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Li, Jiayun, Zhikai Wang, and Douglas T. Fearon. "CD40 signaling induces type I interferon and immune control in mouse pancreatic cancer lacking the CXCL12-coat." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 241.37. http://dx.doi.org/10.4049/jimmunol.204.supp.241.37.
Full textBuchholz, David E., Thomas S. Carroll, Arif Kocabas, Xiaodong Zhu, Hourinaz Behesti, Phyllis L. Faust, Lauren Stalbow, Yin Fang, and Mary E. Hatten. "Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics." Proceedings of the National Academy of Sciences 117, no. 26 (June 16, 2020): 15085–95. http://dx.doi.org/10.1073/pnas.2000102117.
Full textLi, Yajuan, Mei Yan, Yong Du, Soyoun Min, Chandra Mohan, and Quanzhen Li. "The anti-oxidative role of glutathione s-transferase mu 2 in anti-GBM induced glomerulonephritis by inhibiting inflammation and oxidative stress (P5121)." Journal of Immunology 190, no. 1_Supplement (May 1, 2013): 137.2. http://dx.doi.org/10.4049/jimmunol.190.supp.137.2.
Full textDe Maio, Diego Javier Prado, Bitha Narayanan, James La Porta, Usha Ganapathi, Ping Xie, and Lori R. Covey. "Activation-dependent post-transcriptional regulation of CD40L mediates B cell development and survival in germinal centers." Journal of Immunology 206, no. 1_Supplement (May 1, 2021): 63.03. http://dx.doi.org/10.4049/jimmunol.206.supp.63.03.
Full textKaur, Sukhbir, Duha Awad, Richard P. Finney, Thomas J. Meyer, Satya P. Singh, Margaret C. Cam, Baktiar O. Karim, Andrew C. Warner, and David D. Roberts. "CD47-Dependent Regulation of Immune Checkpoint Gene Expression and MYCN mRNA Splicing in Murine CD8 and Jurkat T Cells." International Journal of Molecular Sciences 24, no. 3 (January 30, 2023): 2612. http://dx.doi.org/10.3390/ijms24032612.
Full textLin, S. C., and J. Stavnezer. "Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter." Molecular and Cellular Biology 16, no. 9 (September 1996): 4591–603. http://dx.doi.org/10.1128/mcb.16.9.4591.
Full textFujisawa, Manabu, Tran B. Nguyen, Yoshiaki Abe, Yasuhito Suehara, Kota Fukumoto, Sakurako Suma, Kensuke Usuki, et al. "Germinal Center B Cells Derived from TET2-Mutated Clonal Hematopoiesis Provide a Microenviromental Niche for Tumor Cells in Angioimmunoblastic T-Cell Lymphoma." Blood 138, Supplement 1 (November 5, 2021): 445. http://dx.doi.org/10.1182/blood-2021-149983.
Full textNarayanan, Bitha, Diego Prado De Maio, Katie Voskoboynik, James La Porta, Ping Xie, and Lori R. Covey. "Activation-dependent Posttranscriptional Regulation of CD40L is Required for an Optimal Germinal Center (GC) response." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 186.16. http://dx.doi.org/10.4049/jimmunol.202.supp.186.16.
Full textPiguet, Pierre Francois, Chen Da Kan, Christian Vesin, Anne Rochat, Yves Donati, and Constance Barazzone. "Role of CD40-CD40L in Mouse Severe Malaria." American Journal of Pathology 159, no. 2 (August 2001): 733–42. http://dx.doi.org/10.1016/s0002-9440(10)61744-0.
Full textDe Maio, Diego Javier Prado, Bitha Narayanan, James La Porta, Ping Xie, and Lori R. Covey. "Activation-dependent post-transcriptional regulation of CD40L mediates B cell development and survival in germinal centers." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 151.6. http://dx.doi.org/10.4049/jimmunol.204.supp.151.6.
Full textKeam, Simon, Heloise Halse, ThuNgoc Nguyen, Minyu Wang, Nicolas Van Kooten Losio, Catherine Mitchell, Franco Caramia, et al. "580 High dose-rate brachytherapy of localized prostate cancer converts tumors from cold to hot." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (November 2020): A614—A615. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0580.
Full textDe Maio, Diego Javier Prado, Usha Ganapathi, and Lori Covey. "Decreased CD40L through disrupted transcriptional stability affects the autoimmune response in a sex-dependent manner in a GVHD model of SLE." Journal of Immunology 208, no. 1_Supplement (May 1, 2022): 112.23. http://dx.doi.org/10.4049/jimmunol.208.supp.112.23.
Full textSaadi, Fareeha, Debanjana Chakravarty, Saurav Kumar, Mithila Kamble, Bhaskar Saha, Kenneth S. Shindler, and Jayasri Das Sarma. "CD40L protects against mouse hepatitis virus-induced neuroinflammatory demyelination." PLOS Pathogens 17, no. 12 (December 13, 2021): e1010059. http://dx.doi.org/10.1371/journal.ppat.1010059.
Full textTay, Neil Q., Debbie C. P. Lee, Yen Leong Chua, Nayana Prabhu, and David Michael Kemeny. "CD40L signaling from CD8+ T cells confers protection against influenza infection." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 56.8. http://dx.doi.org/10.4049/jimmunol.196.supp.56.8.
Full textIciek, L. A., S. A. Delphin, and J. Stavnezer. "CD40 cross-linking induces Ig epsilon germline transcripts in B cells via activation of NF-kappaB: synergy with IL-4 induction." Journal of Immunology 158, no. 10 (May 15, 1997): 4769–79. http://dx.doi.org/10.4049/jimmunol.158.10.4769.
Full textAslam, Mohammad, Yusuke Kishi, and Takeshi Tsubata. "Excess CD40L does not rescue anti-DNA B cells from clonal anergy." F1000Research 2 (October 17, 2013): 218. http://dx.doi.org/10.12688/f1000research.2-218.v1.
Full textAslam, Mohammad, Yusuke Kishi, and Takeshi Tsubata. "Excess CD40L does not rescue anti-DNA B cells from clonal anergy." F1000Research 2 (January 15, 2014): 218. http://dx.doi.org/10.12688/f1000research.2-218.v2.
Full textChen, F. A., S. S. Williams, W. C. Fanslow, and R. B. Bankert. "Human antibody response in human peripheral blood leukocyte/severe combined immunodeficient chimeric model is dependent on B and T cell costimulation via CD40/CD40 ligand." Journal of Immunology 155, no. 6 (September 15, 1995): 2833–40. http://dx.doi.org/10.4049/jimmunol.155.6.2833.
Full textWang, Ruikun, Jingru Chen, Wei Wang, Zhuoqian Zhao, Haoran Wang, Shiyu Liu, Fan Li, et al. "CD40L-armed oncolytic herpes simplex virus suppresses pancreatic ductal adenocarcinoma by facilitating the tumor microenvironment favorable to cytotoxic T cell response in the syngeneic mouse model." Journal for ImmunoTherapy of Cancer 10, no. 1 (January 2022): e003809. http://dx.doi.org/10.1136/jitc-2021-003809.
Full textRudqvist, Nils, Claire Lhuillier, Maud Charpentier, Erik Wennerberg, Sheila Spada, Caroline Sheridan, Xi Kathy Zhou, et al. "465 Radiotherapy and CTLA-4 blockade expand anti-tumor T cells differentiation states and cooperate with CD40 agonist to induce tumor rejection." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (November 2020): A494—A495. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0465.
Full textSharma, Madhav D., Maria Leite de Moraes, Flora Zavala, Christiane Pontoux, and Martine Papiernik. "Induction and Inhibition of CD40-CD40 Ligand Interactions: A New Strategy Underlying Host-Virus Relationships." Journal of Immunology 161, no. 10 (November 15, 1998): 5357–65. http://dx.doi.org/10.4049/jimmunol.161.10.5357.
Full textCheng, Wei, Fangfang Wang, Airan Feng, Xiaodan Li, and Wencheng Yu. "CXXC5 Attenuates Pulmonary Fibrosis in a Bleomycin-Induced Mouse Model and MLFs by Suppression of the CD40/CD40L Pathway." BioMed Research International 2020 (April 4, 2020): 1–15. http://dx.doi.org/10.1155/2020/7840652.
Full textKato, T., R. Hakamada, H. Yamane, and H. Nariuchi. "Induction of IL-12 p40 messenger RNA expression and IL-12 production of macrophages via CD40-CD40 ligand interaction." Journal of Immunology 156, no. 10 (May 15, 1996): 3932–38. http://dx.doi.org/10.4049/jimmunol.156.10.3932.
Full textChen, Qing-Quan, Min Chen, Li-Hua Zhang, Yu Zeng, Liu Qi-Cai, Xiu-Lin Yang, and Xu-Chen Lin. "Costimulation blockade by combining CTLA4Ig with anti-CD40L mAb markedly inhibits the inflammatory response of experimental autoimmune myocarditis." European Journal of Inflammation 15, no. 1 (January 16, 2017): 28–34. http://dx.doi.org/10.1177/1721727x16686980.
Full textBlossom, S., E. B. Chu, W. O. Weigle, and K. M. Gilbert. "CD40 ligand expressed on B cells in the BXSB mouse model of systemic lupus erythematosus." Journal of Immunology 159, no. 9 (November 1, 1997): 4580–86. http://dx.doi.org/10.4049/jimmunol.159.9.4580.
Full textSarma, Jayasri Das, Fareeha Saadi, Debanjana Chakravarty, Saurav Kumar, Mithila Kamble, Reas Khan, and Kenneth S. Shindler. "CD40-CD40L interaction is critical in mounting host immunity against m-CoV Mouse Hepatitis Virus induced neuroinflammatory demyelination." Journal of Immunology 206, no. 1_Supplement (May 1, 2021): 53.05. http://dx.doi.org/10.4049/jimmunol.206.supp.53.05.
Full textRalph, Kerry L. M., Mark Panzenbeck, Haiguang Xiao, Lee Frego, Tammy Bigwarfe, Erica Waltz, Christine Grimaldi, et al. "Identification and characterization of an antagonistic anti-mouse CD40 antibody." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 70.19. http://dx.doi.org/10.4049/jimmunol.196.supp.70.19.
Full textLopez-Saucedo, Catalina, Rodolfo Bernal-Reynaga, Jesus Zayas-Jahuey, Silvia Galindo-Gomez, Mineko Shibayama, Carlos Garcia-Galvez, Sergio Estrada-Parra, and Teresa Estrada-Garcia. "CD40 Ligand Deficient C57BL/6 Mouse Is a Potential Surrogate Model of Human X-Linked Hyper IgM (X-HIGM) Syndrome for Characterizing Immune Responses against Pathogens." BioMed Research International 2015 (2015): 1–11. http://dx.doi.org/10.1155/2015/679850.
Full textGurunathan, Sanjay, Kari R. Irvine, Chang-You Wu, Jeffrey I. Cohen, Elaine Thomas, Calman Prussin, Nicholas P. Restifo, and Robert A. Seder. "CD40 Ligand/Trimer DNA Enhances Both Humoral and Cellular Immune Responses and Induces Protective Immunity to Infectious and Tumor Challenge." Journal of Immunology 161, no. 9 (November 1, 1998): 4563–71. http://dx.doi.org/10.4049/jimmunol.161.9.4563.
Full textBalasa, B., T. Krahl, G. Patstone, J. Lee, R. Tisch, H. O. McDevitt, and N. Sarvetnick. "CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice." Journal of Immunology 159, no. 9 (November 1, 1997): 4620–27. http://dx.doi.org/10.4049/jimmunol.159.9.4620.
Full textWiley, J. A., and A. G. Harmsen. "CD40 ligand is required for resolution of Pneumocystis carinii pneumonia in mice." Journal of Immunology 155, no. 7 (October 1, 1995): 3525–29. http://dx.doi.org/10.4049/jimmunol.155.7.3525.
Full textSnyder, James T., Jijia Shen, Hooman Azmi, Jeannie Hou, Daniel H. Fowler, and Jack A. Ragheb. "Direct inhibition of CD40L expression can contribute to the clinical efficacy of daclizumab independently of its effects on cell division and Th1/Th2 cytokine production." Blood 109, no. 12 (June 15, 2007): 5399–406. http://dx.doi.org/10.1182/blood-2006-12-062943.
Full textWang, Qiuli, Muwen Yang, Ye Zhang, Li Zhong, and Xinyu Zheng. "Novel Combination Oncolytic Adenoviral Gene Therapy Armed with Dm-dNK and CD40L for Breast Cancer." Current Gene Therapy 19, no. 1 (May 28, 2019): 54–65. http://dx.doi.org/10.2174/1566523219666190307094713.
Full textTay, Neil, Nayana Prabhu Padubidhri, Hok Sum Wong, Yen Chua, and David Kemeny. "Expression of CD40L on CD8 T cells and its role in influenza A infection (IRC5P.618)." Journal of Immunology 194, no. 1_Supplement (May 1, 2015): 58.1. http://dx.doi.org/10.4049/jimmunol.194.supp.58.1.
Full textAmirkhosravi, Ali, Todd V. Meyer, Liza Robles-Carillo, Monica Davila, Florian Langer, Hina Desai, Patricia Weinstein, Mildred Amaya, Eduardo Reyes, and John L. Francis. "Mechanism of Thrombocytopenia Induced by Anti-CD40 Ligand Immune Complexes and the Prevalence of CD40 Ligand Autoantibodies in Patients with Thrombotic Autoimmune Disorders." Blood 112, no. 11 (November 16, 2008): 2857. http://dx.doi.org/10.1182/blood.v112.11.2857.2857.
Full textChen, Lili, Wen Cheng, Pooja Shivshankar, Lei Lei, Xiaoyun Zhang, Yimou Wu, I.-Tien Yeh, and Guangming Zhong. "Distinct Roles of CD28- and CD40 Ligand-Mediated Costimulation in the Development of Protective Immunity and Pathology during Chlamydia muridarum Urogenital Infection in Mice." Infection and Immunity 77, no. 7 (April 27, 2009): 3080–89. http://dx.doi.org/10.1128/iai.00611-08.
Full textChamekh, Mustapha, Vincent Vercruysse, Mohammed Habib, Maxime Lorent, Michel Goldman, Abdelmounaïm Allaoui, and Bernard Vray. "Transfection of Trypanosoma cruzi with Host CD40 Ligand Results in Improved Control of Parasite Infection." Infection and Immunity 73, no. 10 (October 2005): 6552–61. http://dx.doi.org/10.1128/iai.73.10.6552-6561.2005.
Full textHe, Qing, Linlin Liu, Qiaoyu Yang, Ailing Wang, Shuo Chen, Ruiyun Li, Yi Huang, et al. "Invariant natural killer T cells promote immunogenic maturation of lung dendritic cells in mouse models of asthma." American Journal of Physiology-Lung Cellular and Molecular Physiology 313, no. 6 (December 1, 2017): L973—L990. http://dx.doi.org/10.1152/ajplung.00340.2016.
Full textRossi, Gabriela, Jolly Sarkar, and Dorothea Scandella. "Long-term induction of immune tolerance after blockade of CD40-CD40L interaction in a mouse model of hemophilia A." Blood 97, no. 9 (May 1, 2001): 2750–57. http://dx.doi.org/10.1182/blood.v97.9.2750.
Full textBai, Yun, Demian Obregon, Huayan Hou, William Nikolic, Takashi Mori, Jin Zeng, Jared Ehrhart, et al. "Active Aβ vaccination-induced Aβ clearance enhanced by suppression of the CD40-CD40L interaction (48.11)." Journal of Immunology 178, no. 1_Supplement (April 1, 2007): S76. http://dx.doi.org/10.4049/jimmunol.178.supp.48.11.
Full textWarren, W. D., and M. T. Berton. "Induction of germ-line gamma 1 and epsilon Ig gene expression in murine B cells. IL-4 and the CD40 ligand-CD40 interaction provide distinct but synergistic signals." Journal of Immunology 155, no. 12 (December 15, 1995): 5637–46. http://dx.doi.org/10.4049/jimmunol.155.12.5637.
Full textLucas, Carrie L., Thomas Fehr, Fabienne Haspot, and Megan Sykes. "CD40L-specific mAb mediates its tolerogenic effects through engagement of FcgRIIB, not via depletion of activated T cells (141.17)." Journal of Immunology 182, no. 1_Supplement (April 1, 2009): 141.17. http://dx.doi.org/10.4049/jimmunol.182.supp.141.17.
Full textVowinkel, Thorsten, Katherine C. Wood, Karen Y. Stokes, Janice Russell, Christian F. Krieglstein, and D. Neil Granger. "Differential expression and regulation of murine CD40 in regional vascular beds." American Journal of Physiology-Heart and Circulatory Physiology 290, no. 2 (February 2006): H631—H639. http://dx.doi.org/10.1152/ajpheart.00733.2005.
Full textYanagawa, Senichiro, Hiroyuki Tahara, Takayuki Shirouzu, Shintaro Kawai, Yuka Tanaka, Kentaro Ide, Shuji Akimoto, and Hideki Ohdan. "Development of a humanized mouse model to analyze antibodies specific for human leukocyte antigen (HLA)." PLOS ONE 16, no. 2 (February 5, 2021): e0236614. http://dx.doi.org/10.1371/journal.pone.0236614.
Full textHashem, Anwar M., Abdullah Algaissi, Anurodh Agrawal, Sawsan Al-amri, Abdulrahman Almasoud, Naif Alharbi, Bi-Hung Peng, Xuguang Li, and Chien-Te Tseng. "CD40-targeted S1 subunit vaccine protects against MERS-CoV and S1-associated pulmonary immunopathology in transgenic human DPP4 mouse model." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 139.10. http://dx.doi.org/10.4049/jimmunol.202.supp.139.10.
Full textKhan, W. I., Y. Motomura, P. A. Blennerhassett, H. Kanbayashi, A. K. Varghese, R. T. El-Sharkawy, J. Gauldie, and S. M. Collins. "Disruption of CD40-CD40 ligand pathway inhibits the development of intestinal muscle hypercontractility and protective immunity in nematode infection." American Journal of Physiology-Gastrointestinal and Liver Physiology 288, no. 1 (January 2005): G15—G22. http://dx.doi.org/10.1152/ajpgi.00159.2004.
Full textKuang, Liang-Jian, Ting-Ting Deng, Qin Wang, Shi-Lin Qiu, Yi Liang, Zhi-Yi He, Jian-Quan Zhang, et al. "Dendritic cells induce Tc1 cell differentiation via the CD40/CD40L pathway in mice after exposure to cigarette smoke." American Journal of Physiology-Lung Cellular and Molecular Physiology 311, no. 3 (September 1, 2016): L581—L589. http://dx.doi.org/10.1152/ajplung.00002.2016.
Full textNgaotepprutaram, Thitirat, Barbara L. F. Kaplan, Robert B. Crawford, and Norbert E. Kaminski. "Differential Modulation by Delta9-Tetrahydrocannabinol (∆9-THC) of CD40 Ligand (CD40L) Expression in Activated Mouse Splenic CD4+ T cells." Journal of Neuroimmune Pharmacology 7, no. 4 (August 1, 2012): 969–80. http://dx.doi.org/10.1007/s11481-012-9390-z.
Full textLee, J. K., N. Seki, T. J. Sayers, J. Subleski, E. M. Gruys, W. J. Murphy, and R. H. Wiltrout. "Constitutive expression of functional CD40 on mouse renal cancer cells: Induction of Fas and Fas-mediated killing by CD40L." Cellular Immunology 235, no. 2 (June 2005): 145–52. http://dx.doi.org/10.1016/j.cellimm.2005.08.029.
Full textChaussabel, Damien, Frédérique Jacobs, Jan de Jonge, Marijke de Veerman, Yves Carlier, Kris Thielemans, Michel Goldman, and Bernard Vray. "CD40 Ligation Prevents Trypanosoma cruziInfection through Interleukin-12 Upregulation." Infection and Immunity 67, no. 4 (April 1, 1999): 1929–34. http://dx.doi.org/10.1128/iai.67.4.1929-1934.1999.
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