Dissertations / Theses on the topic 'CB₂'
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Köhler, Martin. "Cb-LIKE." Diss., Ludwig-Maximilians-Universität München, 2015. http://nbn-resolving.de/urn:nbn:de:bvb:19-185151.
Full textThunderstorm cells with their adverse weather hazards like heavy rain, hail or downbursts cause delays and flight cancellations at airports and, as a negative result, the airlines and airport operators have to bear high additional cost. A reliable thunderstorm forecast up to several hours could provide more time for the decision makers at the airport for an appropriate reaction on possible storm cells and initiation of adequate counteractions. To provide the required thunderstorm forecasts up to six hours Cb-LIKE has been developed at the DLR (Deutsches Zentrum für Luft- und Raumfahrt) Institute of Atmospheric Physics. The development of the new algorithm is described in detail in the present dissertation. Cb-LIKE is an automated system which designates areas with possible thunderstorm development by using model data of the COSMO-DE numerical weather prediction model, which is driven by the German Meteorological Service (DWD). Four atmospheric parameters (CAPE, vertical wind velocity, radar reflectivity and cloud top temperature) of the model output are used within the system. A newly developed “Best-Member-Selection“ allows the automatic selection of that model run of a COSMO-DE model ensemble which matches best the observed storm situation. Thereby, the application of the best available data basis for the calculation of the thunderstorm forecasts is ensured. Altogether there are four different modes for the selection of the best member. A newly developed fuzzy logic system enables the subsequent combination of the model data and the calculation of a thunderstorm indicator within a value range of 11. ¯ 66 up to 88. ¯ 33 for each grid point of the model domain for the following six hours in hourly intervals. The higher the indicator the more the model parameters imply the development of thunderstorms. The forecasting quality of the new algorithm is demonstrated by a thorough verification using a neighborhood verification approach and multi-event contingency tables. For the summer period of 2012 Cb-LIKE shows better results in the verification scores in comparison to the COSMO-DE radar reflectivity. For example the new algorithm features a lower „False Alarm Ratio“ (0,48 to 0,56) and a higher „Probability of Detection“ (0,52 to 0,45) and „Critical Success Index“ (0,50 to 0,48). The results show that Cb-LIKE is a sensible novel approach to obtain probabilistic thunderstorm forecasts of high quality on the data basis of the COSMO-DE model. Finally, the implementation of the Cb-LIKE forecasts into the WxFUSION system which is a graphical user interface is presented.
Schreier, Martin. "The value increment of mass-customized products: An empirical assessment." Wiley-Blackwell, 2006. http://dx.doi.org/10.1002/cb.183.
Full textRuzeviciute, Ruta, and Bernadette Kamleitner. "Attracting new customers to loyalty programs: The effectiveness of monetary versus non-monetary loyalty programs." John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/cb.1663.
Full textBayer, Michael J. "Neue Carborane aus CB 2 -, CB 3 - und C 2 B 2 -Organoboranen." [S.l. : s.n.], 2002. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB9837041.
Full textSomani, Hanif. "Novel analogues of CB 1954." Thesis, Institute of Cancer Research (University Of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338418.
Full textPřech, Zdeněk. "Posouzení finančního zdraví společnosti CB Auto, a.s." Master's thesis, Vysoká škola ekonomická v Praze, 2014. http://www.nusl.cz/ntk/nusl-264297.
Full textKiill, Noélle Egídia Watanabe. "Efeito da inibição dos receptores canabinóides CB₁ ou CB₂ durante o período neonatal sobre o dimorfismo sexual esquelético ao longo do desenvolvimento /." Araçatuba, 2015. http://hdl.handle.net/11449/134199.
Full textCoorientador: José Antunes Rodrigues
Banca: Roberta Okamoto
Banca: Keico Okino Nonaka
Resumo: O objetivo do presente estudo foi caracterizar o impacto da breve bloqueio dos receptores canabinóides CB1 ou CB2 durante o período neonatal sobre o crescimento somático e desenvolvimento esquelético durante a infância, puberdade e na idade adulta em ratos. Ratos Wistar recém-nascidos foram distribuídos aleatoriamente em seis grupos, três grupos do sexo masculino e três grupos femininos. Os grupos tratados receberam durante os primeiros sete dias de vida de uma dose subcutânea de antagonistas dos receptores CB1 (AM251) ou CB₂ (SR144528) (3 mg/kg dissolvidos em 50 uL de veículo composto em álcool absoluto e tampão fosfato salino - PBS). Os grupos controle receberam a solução veículo com mesmo volume e período. O peso corporal foi mensurado aos 20, 40, 120 dias de idade e os fêmures direitos foram coletados. O comprimento e a espessura dos fêmures foram medidos e a densidade mineral óssea areal (DMO areal) foi determinada por meio de um densitômetro de dupla emissão de raios-X (DEXA). O teste biomecânico de flexão da cabeça do fêmur foi utilizado para avaliar a força máxima, a energia para fratura, e rigidez extrínseca dos ossos. Ganho de massa corporal, DMO areal e propriedades biomecânicas do osso aumentaram rapidamente com a idade em todos os grupos. Entre animais veículo, os padrões de dimorfismo sexual esquelética foram evidentes após a puberdade. No entanto, o bloqueio neonatal dos receptores canabinóides CB1 e CB2 promoveu um efeito transitório e sexo-dependentes sobre a massa corporal e desenvolvimento ósseo ao longo da vida, e que a inibição neonatal desses receptores nos machos promoveu um efeito bifásico sobre a aquisição de DMO areal ao longo do desenvolvimento, e aumento da fragilidade óssea nos machos AM251 na idade adulta. Este estudo demonstrou que...
Abstract: The aim of the present study was to characterize the impact of brief blockade of cannabinoid CB1 or CB2 receptors during neonatal period on somatic growth and skeletal development during childhood, puberty, and adulthood in rats. Newborn Wistar rats were randomly divided into six groups, three male groups and three female groups. The treated groups received during the firsts seven days of life a subcutaneous dose of a CB1 (AM251) or CB₂ (SR144528) receptors antagonist (3 mg/kg dissolved in 50 μl of a vehicle consisting of absolute ethanol and phosphate buffered saline - PBS). Control groups received the vehicle solution in the same volume and period. Body weight was measured at 20, 40, 120 days of age and femurs were collected. The length and thickness of the femurs were measured and the areal bone mineral density (areal BMD) was determined by dual-energy X-ray absorptiometry (DEXA). Biomechanical femoral neck bending testing was used to evaluate bone breaking strength, energy to fracture, and extrinsic stiffness. Weight gain, areal BMD and bone biomechanical properties increased rapidly with respect to age in all groups. In vehicle animals, skeletal sexual dimorphism patterns were evident after puberty. However, neonatal blockade of cannabinoid CB1 and CB2 receptors promoted a transient and sex-dependent effect on the body weight and bone development throughout the life, and that neonatal inhibiting the CB1 and CB2 receptors in males promotes a biphasic effect on the acquisition of areal BMD throughout development, and increased bone fragility in males AM251 in adulthood. This study demonstrated that brief blockade of cannabinoid CB1 or CB2 receptors during neonatal period causes a long-lasting and sex-dependents modification in somatic growth and skeletal development in rats
Mestre
Kiill, Noélle Egídia Watanabe [UNESP]. "Efeito da inibição dos receptores canabinóides CB₁ ou CB₂ durante o período neonatal sobre o dimorfismo sexual esquelético ao longo do desenvolvimento." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/134199.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O objetivo do presente estudo foi caracterizar o impacto da breve bloqueio dos receptores canabinóides CB1 ou CB2 durante o período neonatal sobre o crescimento somático e desenvolvimento esquelético durante a infância, puberdade e na idade adulta em ratos. Ratos Wistar recém-nascidos foram distribuídos aleatoriamente em seis grupos, três grupos do sexo masculino e três grupos femininos. Os grupos tratados receberam durante os primeiros sete dias de vida de uma dose subcutânea de antagonistas dos receptores CB1 (AM251) ou CB₂ (SR144528) (3 mg/kg dissolvidos em 50 uL de veículo composto em álcool absoluto e tampão fosfato salino - PBS). Os grupos controle receberam a solução veículo com mesmo volume e período. O peso corporal foi mensurado aos 20, 40, 120 dias de idade e os fêmures direitos foram coletados. O comprimento e a espessura dos fêmures foram medidos e a densidade mineral óssea areal (DMO areal) foi determinada por meio de um densitômetro de dupla emissão de raios-X (DEXA). O teste biomecânico de flexão da cabeça do fêmur foi utilizado para avaliar a força máxima, a energia para fratura, e rigidez extrínseca dos ossos. Ganho de massa corporal, DMO areal e propriedades biomecânicas do osso aumentaram rapidamente com a idade em todos os grupos. Entre animais veículo, os padrões de dimorfismo sexual esquelética foram evidentes após a puberdade. No entanto, o bloqueio neonatal dos receptores canabinóides CB1 e CB2 promoveu um efeito transitório e sexo-dependentes sobre a massa corporal e desenvolvimento ósseo ao longo da vida, e que a inibição neonatal desses receptores nos machos promoveu um efeito bifásico sobre a aquisição de DMO areal ao longo do desenvolvimento, e aumento da fragilidade óssea nos machos AM251 na idade adulta. Este estudo demonstrou que...
The aim of the present study was to characterize the impact of brief blockade of cannabinoid CB1 or CB2 receptors during neonatal period on somatic growth and skeletal development during childhood, puberty, and adulthood in rats. Newborn Wistar rats were randomly divided into six groups, three male groups and three female groups. The treated groups received during the firsts seven days of life a subcutaneous dose of a CB1 (AM251) or CB₂ (SR144528) receptors antagonist (3 mg/kg dissolved in 50 μl of a vehicle consisting of absolute ethanol and phosphate buffered saline - PBS). Control groups received the vehicle solution in the same volume and period. Body weight was measured at 20, 40, 120 days of age and femurs were collected. The length and thickness of the femurs were measured and the areal bone mineral density (areal BMD) was determined by dual-energy X-ray absorptiometry (DEXA). Biomechanical femoral neck bending testing was used to evaluate bone breaking strength, energy to fracture, and extrinsic stiffness. Weight gain, areal BMD and bone biomechanical properties increased rapidly with respect to age in all groups. In vehicle animals, skeletal sexual dimorphism patterns were evident after puberty. However, neonatal blockade of cannabinoid CB1 and CB2 receptors promoted a transient and sex-dependent effect on the body weight and bone development throughout the life, and that neonatal inhibiting the CB1 and CB2 receptors in males promotes a biphasic effect on the acquisition of areal BMD throughout development, and increased bone fragility in males AM251 in adulthood. This study demonstrated that brief blockade of cannabinoid CB1 or CB2 receptors during neonatal period causes a long-lasting and sex-dependents modification in somatic growth and skeletal development in rats
Layouni, Khaled. "Comportement et fatigue multiaxiale d'un élastomère chargé (NR-CB)." Paris, ENMP, 2004. http://www.theses.fr/2004ENMP1242.
Full textThis work explores the mechanical behaviour of a carbon-black reinforced natural rubber (NR-CB) subjected to monotonic, cyclic, uniaxial and multiaxial loading. Several physical phenomena have been identified. In particular, we have characterised the material compressibility under various kinds of loading conditions and confirmed the results by means of microscopic observations. Consequently, in order to describe the material behaviour, we have considered and compared two constitutive models: the first one is hyperelastic incompressible whereas the second one is more realistic as it uses a damage-induced compressible approach. Furthermore, fatigue experimental results obtained under complex loading histories allow to describe the interaction between axial and torsional loading. In particular, the phase angle effect on the lifetime and the crack location have been determined. These analyses were supported by fractographic observations that allow the identification of different tearing steps (macroscopic scale) and initiation sites (microscopic scale). Finally, we have established a model able to predict the location and orientation of cracks, as well as lifetime under complex loading. This criterion has been validated for complex geometry and industrial components. Finally, we have compared this model with another taken in literature
Ghosh, Sumana. "CANNABINOID RECEPTORS (CB) IN COCHLEA: CHARACTERIZATION AND OTOPROTECTIVE FUNCTIONS." OpenSIUC, 2017. https://opensiuc.lib.siu.edu/dissertations/1486.
Full textVan, den Hooff Jelle (Jelle August). "Fast bug finding in lock-free data structures with CB-DPOR." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/92058.
Full textThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (pages 39-40).
This thesis describes CB-DPOR, an algorithm for quickly finding bugs in lock-free data structures. CB-DPOR is a combination of the CHESS and DPOR model checking algorithms. CB-DPOR performs similar to the concurrently developed preemption-bounded BPOR algorithm. CODEX is a tool for finding bugs in lock-free data structures. CODEX implements CBDPOR and this thesis demonstrates how to use CODEX to find bugs. This thesis describes new bugs in open-source lock-free data structures, and compares the performance of CBDPOR with the earlier model checking algorithms CHESS, DPOR, and PCT. CB-DPOR find bugs one to two orders of magnitude faster than earlier algorithms.
by Jelle van den Hooff.
M. Eng.
OLIVEIRA, Marcio Mosiel do Nascimento. "O caráter educativo do CDVDH/CB no enfrentamento ao trabalho escravo." Universidade Federal do Pará, 2017. http://repositorio.ufpa.br/jspui/handle/2011/9324.
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Esta dissertação desenvolve um estudo sobre a educação trabalhada no Centro de Defesa da Vida e dos Direitos Humanos Carmem Bascarán – CDVDH/CB. O objetivo geral do trabalho foi analisar o caráter educativo do CDVDH/CB presente em suas ações no enfrentamento ao trabalho escravo contemporâneo, na cidade de Açailândia-MA. Os objetivos específicos foram os seguintes: a) verificar como ocorrem as parceiras com outras instituições para o desenvolvimento das ações educacionais de enfrentamento ao trabalho escravo; b) avaliar como acontece a formação dos educadores e lideranças que atuam no CDVDH/CB c) compreender a metodologia do CDVDH/CB a partir de suas ações. Foram estudadas as seguintes categorias: trabalho, trabalho escravo contemporâneo, educação não formal e direitos humanos. A metodologia deste trabalho baseou-se na modalidade de pesquisa analítica de natureza qualitativa. Na busca dos dados, recorremos aos seguintes instrumentos metodológicos: pesquisa bibliográfica, documental e entrevista semiestruturada. Para contextualização da problemática do trabalho escravo contemporâneo e o espaço geográfico da Amazônia Oriental, onde ele tem grande incidência, localidade de atuação do CDVDH/CB, buscamos aporte teórico no materialismo histórico-dialético marxista. Defrontando-nos com as entrevistas, podemos conhecer a forma como são trabalhadas as ações educativas, as parcerias, a formação de educadores e a metodologia do CDVDH/CB e, a partir daí, conhecer o seu caráter educativo. Diante do estudo, foi possível perceber o envolvimento dos que fazem o CDVDH/CB, além de conhecer as particularidades da educação desenvolvida no movimento social.
This Dissertation develops a study about education performed in Center of the Defense of Life and Human Rights Carmen Bascarán (in Portuguese, Centro de Defesa da Vida e dos Direitos Humanos - CDVDH/CB). The general goal of the study was to analyze the educational features of the CDVDH/CB present in its actions in confrontation with contemporary slave labor, in Açailândia city, state of Maranhão, Brazil. The specific goals were: a) verifying how the partnerships with other institutions occur for the development of educational actions to confront to the slave labor; b) evaluating how the educators’ formation occurs and the leaderships that preside in CDVDH/CB; c) understanding the methodology of CDVDH/CB from their actions. We study the following categories: labor, contemporary slave labor, non-formal education and human rights. The methodology of this paper was based on the model of qualitative analysis research. In search of data, we appealed the following methodological instruments: bibliographical research, documental research and semi-structured interview. In order to contextualize the contemporary slave labor problem and the geographic space of Eastern Amazon, where it has a great incidence, local of CDVDH/CB, we seek theoretical support in Marxist historical-dialectical materialism. When we confront the interviews, we can know how the educational actions are worked, the partnerships, the educators’ formation and the methodology of CDVDH/CB and, then, to know its educational features. Before the study, it was possible to perceive the involvement of those who make the CDVDH / CB, besides knowing the particularities of the education developed in the social movement.
Drakoulis, Dimitris P. "The Regional Organization of the Eastern Roman Empire in the Early Byzantine Period (4th-6th Century A.D.)." Diss., Aristotle University of Thessaloniki, 2009. http://hdl.handle.net/10919/71524.
Full textLu, Yongchao. "On the Classification of Rank-1 Four-dimensional N=2 Superconformal Field Theories by Seiberg-Witten Geometry." University of Cincinnati / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1505211291169085.
Full textRaduner, Stefan Andreas. "Binding and functional studies on new plant-derived CB₂ receptor-selective cannabinomimetics /." Zürich : ETH, 2008. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=17707.
Full textLand, Chris. "Technologies, texts and subjects : William S. Burroughs and post-humanism." Thesis, University of Warwick, 2004. http://wrap.warwick.ac.uk/1216/.
Full textChoe, Boyun. "Cultural politics of creativity : a comparative study of the development of the cultural policy discourses of creativity in England and Korea." Thesis, University of Warwick, 2010. http://wrap.warwick.ac.uk/3132/.
Full textAbu, Elmeaza Mohammed Salim. "Edward Said : the political intellectual & public spheres." Thesis, University of Nottingham, 2015. http://eprints.nottingham.ac.uk/14581/.
Full textBelfiore, Eleonora. "Ubi maior, minor cessat : a comparative study of the relation between changing cultural policy rationales and globalization in post-1980s England and Italy." Thesis, University of Warwick, 2006. http://wrap.warwick.ac.uk/1166/.
Full textBilton, Chris. "Towards cultural democracy : contradiction and crisis in British and U.S. cultural policy 1870-1990." Thesis, University of Warwick, 1997. http://wrap.warwick.ac.uk/36329/.
Full textPennick, Morgan Faith. "Dress and personal appearance in Late Antiquity : the clothing of the middle and lower classes." Thesis, University of Kent, 2014. https://kar.kent.ac.uk/50489/.
Full textTshitenge, Tshibuayi Christine. "Immunopathologie des infections Plasmodium chabaudi virulantes et non virulantes dans les souris C57BL/6." Thesis, Montpellier 2, 2012. http://www.theses.fr/2012MON20248/document.
Full textPlasmodium species induces a specific immune response, stimulating the release of cytokines, resulting in either protective or pathological responses. In mouse models, this is depended on mouse strain or parasite combination used. C57BL/6 infected with relatively low numbers of Plasmodium chabaudi AS pRBC experience a non-lethal infection and resistance is associated with robust inflammatory responses that involves IL-12, early activation of CD4+Th1 cells with production of high levels of IFN-γ and TNF-α, this pro-inflammatory response is subsequently controlled by IL-10 leading to control and resolution of infection. However, mice that succumb to infection develop fulminant parasitaemia and increase mortality. The cause of the differences in infection outcome is not well understood, although the principal components of protective and pathological immune responses are well known. Using the model of Plasmodium chabaudi in C57BL/6, this study addresses the following; 1) compares the course of infection and pathology between the relatively avirulent P. chabaudi AS and the more virulent P. chabaudi CB; 2) investigates whether differences in parasite replication, parasite load or host immune responses contribute to differences in pathology; 3) what mediates the differences in host immune response? P. chabaudi CB causes a more severe infection in C57BL/6 compared to P. chabaudi AS, with ±40% mortality within 12 days and mean peak parasitaemia of 50% compared to 30% in P. chabaudi AS infected mice. There was no difference in total body parasite load between the P. chabaudi AS and CB infections. A High number of NK cells was found in the spleen of P. chabaudi AS infected mice at peak parasitaemia, whereas NK cells numbers in spleen of P. chabaudi CB infected mice remained constant throughout infection. Hence, the elevated NK cells contribute to parasite clearance in the avirulent P. chabaudi AS clone, because of its IFN-γ production and cytolytic activity. P. chabaudi CB infected C57BL/6 were found to have reduced number of CD4+T cells in the spleen, with 1-fold decrease in IFN-γ+CD4+T cells and 2-fold decrease in IL-10+ CD4+T cells when compared to CD4+T cells from P. chabaudi AS infected mice. Further analysis showed that IL-10+IFN-γ+CD4+T cells were more prevalent in P. chabaudi AS infected mice. The absence of IL-10+IFN-γ+CD4+T cells in P. chabaudi CB infected C57BL/6 contributes to pathology, because these cells limit lethal inflammatory responses and ameliorate weight loss, hypothermia and anemia, by regulating immunopathology. The differences observed in immune responses are not mediated by interaction of parasite specific GPIs with TLR2, but rather by IFN-α/β. Although IFN-α/β were not detected in plasma, higher levels of IFN-α/β mRNA transcripts were found in the spleen of P. chabaudi CB infected C57BL/6 on day 5. IFN-α/βR deficiency limits virulent P. chabaudi CB infections with no effect on avirulent P. chabaudi AS infections
Tadini, Maraine Catarina. "Desenvolvimento de sensores eletroquímicos para a detecção voltamétrica de MDMA em amostras de interesse forense." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/59/59138/tde-07122016-111207/.
Full textThe 3,4-methylenedioxymethamphetamine (MDMA) is the main psychoactive component of ecstasy tablets, that have an illicit trade. MDMA has been an illicit psychotropic drug, and it has a prohibited use (group F2, in ANVISAs F list), because of its hallucinogenic and stimulating effects, and the use/abuse can poses serials health risks. The development of chemically modified electrodes (CME) in electroanalytical methods aims to get more sensitive and selective systems to detect the analytes. In this context, it is necessary to develop new techniques and methodologies to the detection of illicit samples; it provides more tools to help the forensic scientists to combat the illicit drug trade. So, this work focused in the development of chemically modified electrodes (CMEs) with modifications on the glassy carbon surface by drop coating and spin coating using Nafion and Nafion/CB[7] solutions. The CMEs were tested using cyclic, and square wave voltammetry to detect MDMA. Considering the employed system, the best CMEs were made by Nafion (1.5% v/v), and Nafion (1.5% v/v)/CB[7] (10.0 µg.mL-1) thin films. It was possible to observe better sensitivities for these sensors, in comparison to other MDMA studies reported in the literature. The specificity of the proposed sensors was checked in relation to other drugs: caffeine, methamphetamine, theobromine, lidocaine, procaine hydrochloride, and cocaine hydrochloride. These drugs do not interfere in this voltammetric method. Additionally, we studied eleven lots of ecstasy samples, allowed by the Scientific Police - Ribeirão Preto-SP, and we provide qualitative and quantitative studies using colorimetric techniques (Marquis, Sulfuric acid, Simon, and Simon with acetone), and chromatografic techniques (GC-MS and HPLC-MS). The MDMA quantification in real samples was obtained by high performance liquid chromatography with a mass spectrophotometer, and we compared with the voltammetric technique, using the developed CME. Between the analyzed lots, two of them didnt present in their composition, one lot had a mix of caffeine and MDMA, and another presented MDMA. The MDMAs concentration in lots had a large variation, with 0 to 61 % w/w. The MDMAs voltammetric detection in ecstasy lots was viable. And, it is also possible to apply this methodology to analyze MDMA traces.
Boulahouache, Chaouki. "Lepton energy moments, operator product expansion and the CKM parameter matrix element, V(cb)." Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available full text, 2002. http://wwwlib.umi.com/cr/syr/main.
Full textOttnad, Jonathan [Verfasser]. "Optimierung der GEM-basierten Verstärkungsstufe einer TPC für das CB/TAPS-Experiment / Jonathan Ottnad." Bonn : Universitäts- und Landesbibliothek Bonn, 2020. http://d-nb.info/1219140015/34.
Full textExaucee, Cherellle Wando-Okomba. "Economic evaluation of alternative strategies of enterprise in case Cb Mtn Group Company PJSC." Thesis, Тернопільський національний технічний університет імені Івана Пулюя, 2017. http://elartu.tntu.edu.ua/handle/123456789/19554.
Full textResearch object looks at Economic evaluation of alternative strategies for en-terprise development MTN group. Driven by its pioneering approach, MTN is a leading emerging markets mobile operator that is at the forefront of the technological changes sweeping the world. They invest in more than 189 million people in 22 countries across Africa and the Middle East. In the past five years, their capital ex¬penditure has exceeded R100 billion. In the pursuit of a new vision of a new generation of people, their lives have be¬come more and more important to them. Quality customer experience. They recognize the value of diversity within a group with a solid organizational culture. Working with integrity, they value their relationships with the communities in which they work, their customers and employees, their shareholders and the media, governments and regulators, as well as suppliers and business partners. They recognize the importance of these stakeholders, among others, in the sus¬tainability of their business. They are a leading emerging markets telecommunications service provider and are headquartered in Johannesburg, South Africa. The company has a listing on the JSE Securities Exchange where it ranks sixth. Through their ex¬tensive investment in advanced communication infrastructure in the past two decades, the talent and experience of their people, as well as the strength of their brand, they have grown rapidly to now have operations in 22 countries across Africa and the Middle East. They provide an integrated approach to the delivery of information and services to their customers. Keywords: Staff, HR management, organization, personnel, risk management process, organizational, structure, instements, innovative, head, finance, stategy.
Chapter I. Theoretical framework and studies of MTN group Chapter II. Research and Analysis of the MTN group syst Chapter III. Recommendation Chapter IV. Special part Chapter V. Rationale for recommendation Chapter VI. Occupational health and safety in emergencies Chapter VII. Environnemental issues
Chan, Chun Tung. "Brand rejuvenation : the case of Playboy in China /." access full-text access abstract and table of contents, 2009. http://libweb.cityu.edu.hk/cgi-bin/ezdb/thesis.pl?dba-cb-b2375090xf.pdf.
Full text"Submitted to College of Business in partial fulfillment of the requirements for the degree of Doctor of Business Administration." Includes bibliographical references (leaves 138-153)
Callén, Herrero Lucía. "Expresión, función y heteromerización de receptores de cannabinoides CB(2) en el sistema nervioso central." Doctoral thesis, Universitat de Barcelona, 2012. http://hdl.handle.net/10803/101513.
Full textTo date the two main receptors of the endocannabinoid system are cannabinoid receptor type 1 and 2 (CB1R and CB2R). While CB1R are known to be widely expressed all over the brain, the putative presence of CB2R in the central nervous system is still a matter of debate. In the present Thesis, we present evidence for the existence of CB2R transcripts in the cerebral cortex, hippocampus brain regions and even in neurons from internal and external divisions of the globus pallidus from primate’s brain. In an embryonic Xenopus laevis model, we have provided data that suggests involvement of CB2R in neural development. CB2R overexpression impairs maxillomandibullar (VII), glossopharyngeal (IX) and vagal (X) cranial nerves development by two differential pathways: activating Akt pathway whilst inhibiting the ERK 1/2 MAPK pathway. This signaling pattern also induces upregulation of genes involved in placodal and cranial nerve development as wnt8, fgf8 and pax2 and concerns CB2R with a putative role in epibranchial placodal progenitor fate. At the molecular level, we have demonstrated that both cannabinoid receptors, CB1R and CB2R, can form heteromers in transfected neuronal cells as well as in the rat brain pineal gland, nucleus accumbens and globus pallidus where they have been seen previously to colocalize. CB1 and CB2 receptor heteromer agonist co-activation leads to a negative cross-talk. In addition, we found that the CB1R-CB2R heteromers demonstrated a bidirectional crossantagonism, the ability of CB1R antagonist to block the effect of CB2 agonists and, conversely, the ability of CB2 antagonists to block the effect of CB1 agonists. Finally, using biophysical approaches we have shown that CB2 can also form heteromers with other neurotransmitter system receptors as adenosine A2A receptor and serotonin 5HT2c receptor. The data presented here gives evidence for the presence of CB2R in the central nervous system with and suggest it may play an important role in neural development and/or as a modulator of CB1R when expressed as a heteromer. These characteristics make it a good candidate for drug design and therapeutic use.
Thammachart, Matina. "Corrosion mechanisms of chemically bonded composite sol-gel (CB-CSG) coating systems in aqueous environment." Thesis, Heriot-Watt University, 2005. http://hdl.handle.net/10399/145.
Full textKöhler, Martin [Verfasser], and George [Akademischer Betreuer] Craig. "Cb-LIKE : Gewittervorhersagen bis zu sechs Stunden mit Fuzzy-Logik / Martin Köhler. Betreuer: George Craig." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2015. http://d-nb.info/1075456703/34.
Full textCarvalho, Sandra Aparecida Portuense de. "Experiências de solidariedade e política: CB-22 a ação popular no jardim Zaíra (1958-1970)." Pontifícia Universidade Católica de São Paulo, 2013. https://tede2.pucsp.br/handle/handle/12780.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior
This dissertation is focused on the experiences which were lived and shared by a group of residents of Jardim Zaíra, in Maua, a city in ABC Paulista, São Paulo between the years 1958 and 1970. Our gaze turns to the experiences related to the urbanization of that place, the relationship of the residents with the Catholic Church and with the Neighborhood Friends Society , the participation of PCdoB members and later on, in 1968, the engagement of those people in a political movement called Popular Action, which through the process titled "integration in production" formed the cell-base-22 and encouraged the militancy against dictatorial government outrages present in Brazil that time .Through Oral History, we tried to analyze testimonials from 11 people who were related to that movement. We also present an assessment of 6 photos that rescue the daily life of those residents as well as the analysis of texts that bring us the vision of their leaders and the analysis of documents produced by the organs of repression that deal about their arrests and trial. The aim is to contribute towards the understanding about the social movement before and after the arrival of Popular Action members to that neighborhood as well as the reasons that brought them there and the experiences derived from this encounter. Similarly, we present the analysis of the CB-22 dismantling. We understand the importance of this movement and its ability to influence others later which helped ABC Paulista region to be known nationally because of the struggles for democracy. In times of Truth Commission, the research aims to broaden discussions not only of social movements, but also about the abuses caused by the organs of repression
Esta dissertação tem como tema central as experiências vividas e compartilhadas por um grupo de moradores do Jardim Zaíra, município de Mauá, região do ABC Paulista, estado de São Paulo, entre os anos de 1958 e 1970. Nosso olhar se volta para as experiências relacionadas ao processo de urbanização daquele lugar, as relações dos moradores junto à Igreja Católica e à Sociedade Amigos de Bairro, a participação de membros do PCdoB e posteriormente, em 1968, o engajamento daquelas pessoas num movimento político intitulado Ação Popular, o qual por meio do processo intitulado integração na produção formou no bairro a Célula-base-22 e incentivou a militância contra as arbitrariedades do governo ditatorial presente no Brasil naquela época. Por meio da História Oral, procuramos analisar depoimentos de 11 pessoas que estiveram relacionadas àquele movimento. Apresentamos também a apreciação de 6 fotos que resgatam o cotidiano daqueles moradores, bem como, a análise de textos que trazem a visão de suas lideranças e a análise de documentos produzidos pelos órgãos de repressão que tratam sobre suas prisões e julgamento. Pretende-se assim contribuir para compreensão a cerca do movimento social antes e depois da chegada dos membros da Ação Popular àquele bairro, bem como os motivos que os levaram até lá e as experiências oriundas desse encontro. Do mesmo modo apresentamos a análise sobre o desmantelamento da CB-22. Compreendemos a importância desse movimento e sua capacidade de posteriormente influenciar outros, que tornaram a região do ABC Paulista conhecida nacionalmente devido às lutas em prol da democracia. Em tempos de Comissão da Verdade a pesquisa visa ampliar as discussões não só dos movimentos sociais, mas dos abusos causados pelos órgãos de repressão
Ingleson, Michael James. "Transition metal complexes partnered with the highly alkylated carborane anion, [1-H-CLOSO-CB₁₁Me₁₁]⁻." Thesis, University of Bath, 2004. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.403685.
Full textHarrisson, Juliette Grace. "Cultural memory and imagination : dreams and dreaming in the Roman Empire 31 BC – AD 200." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/469/.
Full textStoner, Jo. "The cultural lives of domestic objects in Late Antiquity." Thesis, University of Kent, 2015. https://kar.kent.ac.uk/50784/.
Full textWalsh, David. "Development, decline and demise : the cult of Mithras ca. AD 270-430." Thesis, University of Kent, 2016. https://kar.kent.ac.uk/56837/.
Full textIngate, Jay. "Hybrid waterscapes : an examination of meaning-laden waterflow in the towns of Roman Britain." Thesis, University of Kent, 2014. https://kar.kent.ac.uk/42901/.
Full textRowlatt, Linnéa. "A godly environment : religious views of nature in early sixteenth-century Strasbourg." Thesis, University of Kent, 2014. https://kar.kent.ac.uk/55002/.
Full textBarfoed, Signe. "Cult in context : the ritual significance of miniature pottery in Ancient Greek sanctuaries from the Archaic to the Hellenistic period." Thesis, University of Kent, 2016. https://kar.kent.ac.uk/54772/.
Full textXu, Lingyu. "Design and implementation of a credible blockchain-based e-health records platform." University of Western Cape, 2020. http://hdl.handle.net/11394/7883.
Full textWith the development of information and network technologies, Electronic Health Records (EHRs) management system has gained wide spread application in managing medical records. One of the major challenges of EHRs is the independent nature of medical institutions. This non-collaborative nature puts a significant barrier between patients, doctors, medical researchers and medical data. Moreover, unlike the unique and strong anti-tampering nature of traditional paper-based records, electronic health records stored in centralization database are vulnerable to risks from network attacks, forgery and tampering. In view of the data sharing difficulties and information security problems commonly found in existing EHRs, this dissertation designs and develops a credible Blockchain-based electronic health records (CB-EHRs) management system.
Arcara, Stefania. "Constructing the south : Sicily, Southern Italy and the Mediterranean in British culture, 1773-1926." Thesis, University of Warwick, 1998. http://wrap.warwick.ac.uk/36389/.
Full textWalkley, Sarah Elizabeth. "To what extent can France continue to defend the cultural exception in the digital age? : an analysis of cultural diversity in the French film industry." Thesis, University of Warwick, 2016. http://wrap.warwick.ac.uk/80230/.
Full textDharaiya, Dhawal. "Effects of Nanoclay and Conductive Carbon Black on Morphology Development in Chaotic Mixing of Immiscible Polymers." University of Akron / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=akron1144957223.
Full textHenriksson, Björn, and Felix Frenzel. "Campusbokhandeln : Investigation of a new Establishement." Thesis, Karlstad University, Faculty of Economic Sciences, Communication and IT, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-3605.
Full textIn the majority of cases students are short of money and have problems to finance their low standard subsistence. An additional financial burden for students is purchasing the costly literature for their courses and studies. Universities often support their students by providing a library but a library can never cover all the books that are demanded. Students often do not need or use their purchased books longer than they have to; with the closure of a course or a semester books become useless for the owner. To get back some money after having used a book it is common to resell the book in various ways. Regularly students’ organisations or universities established some sort of platform for example a bill-board in their facilities or on the internet. But the existence of these platforms made trading the used literature not easier because there are no rules and no regulations. The store Campusbokhandeln took this problem and started a business to make it easier for students to sell and buy used books with fair regulations so every participator profits. Campusbokhandeln has a main store at Örebro University and one at Karlstad University. The purpose of the study is to find out whether Campusbokhandeln is able to expand their actions to another university in Sweden and if yes to which university. The results of the research show that the demand for a platform like Campusbokhandeln if very high and that the owners can take the chance to expand. After a SWOT-analysis we were able to point out chances and give suggestions about the future of the business.
Ma, Wenqian. "Dlx Gene Regulation of Zebrafish GABAergic Interneuron Development." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/19970.
Full textBessi, Ourania. "The Ottoman town in the Southern Balkans from 14th to 16th centuries : a morphological approach." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/5473/.
Full textStern, Eric. "Nouveaux agonistes des récepteurs aux cannabinoïdes CB², dérivés de 4-oxo-quinoléines, 4-oxo-naphtyridines et 4-oxo-cinnolines." Lille 2, 2006. http://www.theses.fr/2006LIL2S013.
Full textCancer, second cause of mortality nad morbidity in the developed countries, just after cardiovascular diseases, results from a deregulation of the genetic cell program leading to its immortality and its uncontroled proliferation. In France in 2004, about 40,000 new cases of prostate cancer were diagnosed. Prostate cancer reaches in general old people and represents the second cause of death per cancer, after lung cancer. Because of the ageing of the population of developed countries, the number of prostate cancer patients will increase. In order to solve problems related to the use of traditional anti-cancer drugs (lack of selectivity, resistance. . . ), the development of new therapeutic strategies to treat prostate cancer proves to be essential. Since 1997, Δ9-THC ( Δ9 – tétrahydrocannabinol, the major psychoactive component of Cannabis sativa L. ) is currently used to treat nausea and emesis in cancer patient undergoing extensive chemotherapy. Moreover some cannabis-based drugs are in phase three clinical trials for treating pain associated with cancer. Since Δ9-THC characterization in the sixties, many improvements have been made in cannabinoid pharmacology knowledge, particularly, in the nineties with the discovery of two G-protein coupled receptors : the CB1 receptor, which is mainly located in the central nervous system (CNS), and the CB2 receptor which is principally present in the immune system. Thanks to the development of a great variety of new synthetic ligands, the study of these receptors has revealed the anticancer potency of the cannabinoid receptors agonists. CB1 receptor stimulation could induce undesirable effects due to its CNS localization, so we proposed to study the anticancer potency of CB2-selective agonists. In order to develop new potent CB2-selective ligands, a 98-compound library was built using a central heterocyclic ring as quinoleine, naphthyridine or cinnoline, substitued in position 3 by various carboxamido substituents, and hydrophobic side chains in the N1-position. Pharmacological results revealed a strong CB2 selectivity, and an agonist profile for all compounds. Thus, some chemical modulations were next realized as : replacement of the carboxamide link, in position 3, by inverse amide analogue or its reduction in secondary amine ; introduction of differentsubstituents on the position 2, 5, 6, 7 and 8 ; modulation of the N1-position side chain. Anticancer potency of these new potent CB2 receptor ligands was investigated using different prostate cancer cell lines
Onge, Mustafa. "Conservation Of Cultural Heritage On Alaeddin Hill In Konya From The 19th Century To Present Day." Phd thesis, METU, 2011. http://etd.lib.metu.edu.tr/upload/12613171/index.pdf.
Full textDodd, Rebecca. "Coinage and conflict : the manipulation of Seleucid political imagery." Thesis, University of Glasgow, 2009. http://theses.gla.ac.uk/938/.
Full textWoddis, Jane. "Spear-carriers or speaking parts? : arts practitioners in the cultural policy process." Thesis, University of Warwick, 2005. http://wrap.warwick.ac.uk/2591/.
Full textHalsted, John Charles. "Settlement patterns from the Late Neolithic to the Late Bronze Age : the central Welsh border region in context." Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3570/.
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