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Journal articles on the topic 'Cargo'

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1

Chen, Sui Lei, Tian Ge Gao, Yin Qing Tu, Xue Nan Wang, and Feng Zhang. "Research of Cargo Truck Model Based on the Lift Bucket." Applied Mechanics and Materials 241-244 (December 2012): 1535–38. http://dx.doi.org/10.4028/www.scientific.net/amm.241-244.1535.

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To deal with the cargo trucks’ problem that handling of cargos is time-consuming due to the buckets of cargos can’t be lifted, this study aims to design a cargo truck with lift bucket. Based on the idea of driving principle, mechanical structure and simulation of overall modeling, this paper proposes a cargo truck model with the lift bucket. Using front-wheel drive, the newly designed cargo truck model drops the bucket near the ground or lands the bucket, which saves manual handling from the original height of bucket to the ground. Thus, operators can load or unload the lift bucket by moving t
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Lopez, Sergio, Ana Maria Perez-Linero, Javier Manzano-Lopez, et al. "Dual Independent Roles of the p24 Complex in Selectivity of Secretory Cargo Export from the Endoplasmic Reticulum." Cells 9, no. 5 (2020): 1295. http://dx.doi.org/10.3390/cells9051295.

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The cellular mechanisms that ensure the selectivity and fidelity of secretory cargo protein transport from the endoplasmic reticulum (ER) to the Golgi are still not well understood. The p24 protein complex acts as a specific cargo receptor for GPI-anchored proteins by facilitating their ER exit through a specialized export pathway in yeast. In parallel, the p24 complex can also exit the ER using the general pathway that exports the rest of secretory proteins with their respective cargo receptors. Here, we show biochemically that the p24 complex associates at the ER with other cargo receptors i
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Ríos-Barrera, L. D., S. Sigurbjörnsdóttir, M. Baer, and M. Leptin. "Dual function for Tango1 in secretion of bulky cargo and in ER-Golgi morphology." Proceedings of the National Academy of Sciences 114, no. 48 (2017): E10389—E10398. http://dx.doi.org/10.1073/pnas.1711408114.

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Tango1 enables ER-to-Golgi trafficking of large proteins. We show here that loss of Tango1, in addition to disrupting protein secretion and ER/Golgi morphology, causes ER stress and defects in cell shape. We find that the previously observed dependence of smaller cargos on Tango1 is a secondary effect. If large cargos like Dumpy, which we identify as a Tango1 cargo, are removed from the cell, nonbulky proteins reenter the secretory pathway. Removal of blocking cargo also restores cell morphology and attenuates the ER-stress response. Thus, failures in the secretion of nonbulky proteins, ER str
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Santana, Leonardo Matos Sampaio, and Joilson Leopoldino Vasconcelos Júnior. "CARGOS COMISSIONADOS: BENÉFICOS OU MALÉFICOS PARA A ADMINISTRAÇÃO PÚBLICA." Revista Ibero-Americana de Humanidades, Ciências e Educação 9, no. 5 (2023): 2334–43. http://dx.doi.org/10.51891/rease.v9i5.9985.

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O presente artigo possui uma abordagem sobre a criação dos cargos comissionados e quais benefícios e malefícios eles podem trazer para administração pública, além de descrever os desafios da administração pública no preenchimento dos mesmos. Sendo assim, é feita uma análise metodológica qualitativa e de revisão bibliográfica, selecionando informações em bases de dados eletrônicas, abordando conceito de administração pública e suas fases de evolução histórica, bem como aspectos teóricos acerca do ingresso no serviço público, cargo, emprego e função pública, cargo vitalício, cargo de provimento
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Castillo Ramos-Bossini, Susana E. "concepto de alto cargo." Revista Andaluza de Administración Pública, no. 113 (August 31, 2022): 75–120. http://dx.doi.org/10.46735/raap.n113.1348.

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Este estudio analiza el concepto de alto cargo desde el punto de vista de la normativa sobre buen gobierno y altos cargos dictada en los últimos años en el ámbito estatal, autonómico y local. La realidad es que el legislador ha hecho de la noción de alto cargo un concepto impreciso e inacabado. Esta cuestión no es de importancia menor, pues de ello dependerá el régimen jurídico del desempeño del cargo y a quiénes se puede exigir la responsabilidad administrativa a que se refieren dichas normas.
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Suzuki, Sho W., Ya-Shan Chuang, Ming Li, Matthew N. J. Seaman, and Scott D. Emr. "A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling." Journal of Cell Biology 218, no. 9 (2019): 2876–86. http://dx.doi.org/10.1083/jcb.201901019.

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Retromer is an evolutionarily conserved protein complex, which sorts functionally diverse membrane proteins into recycling tubules/vesicles from the endosome. Many of the identified cargos possess a recycling signal sequence defined as ØX[L/M/V], where Ø is F/Y/W. However, this sequence is present in almost all proteins encoded in the genome. Also, several identified recycling sequences do not follow this rule. How then does retromer precisely select its cargos? Here, we reveal that an additional motif is also required for cargo retrieval. The two distinct motifs form a bipartite recycling sig
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7

Ojutalayo, John F., Kenneth U. Nnadi, Obed B. Ndikom, Bonaventure A. C. Akujuobi, and Theophilus C. Nwokedi. "Assessment of the Influence of Maritime Piracy and Sea Robbery on Cargo throughput Performance of Nigerian Ports." European Journal of Maritime Research 2, no. 3 (2023): 1–4. http://dx.doi.org/10.24018/maritime.2023.2.3.1.

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The study assessed the impact of maritime piracy and sea robbery on the cargo throughput performance of Nigeria ports. The central objective of the study was to determine the significances of the influences of levels of attacks against ships trading in global cum local waters and maritime insecurity induced cargo pilferage levels on the cargo throughput performance of Nigeria ports. The study used secondary data sourced from the Nigerian ports authority, and the International Maritime Bureau (IMB) on the cargo throughput, levels of pirate attacks against ships in local; and global waters, leve
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8

Xavier de Menezes, Raimundo. "Descrições de cargos." Revista do Serviço Público 72, no. 03 (2020): 257–65. http://dx.doi.org/10.21874/rsp.v72i3.4369.

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Descrições de cargos: conceituação — Uma descrição de cargo consistena exposição escrita de fatos importantes para a administração e concernentesàs atribuições, responsabilidades e relações organizacionais inerentes a umcargo. O conteúdo de cada cargo aparece em combinações tão variadas quesua descrição não pode integrar-se numa fórmula rígida, com itens predeterminados.Conseqüentemente, a parte principal da descrição do cargo é usualmentedactilografada numa fôlha de papel comum e anexada a modelo próprio,que consiste, antes de tudo, numa capa, utilizada para fins de identificaçãoe autenticaçã
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9

Guzmán-Brito, Alejandro. "Las principales diferencias de la organización administrativa de la época republicana y de la época imperial." Revista Digital de Derecho Administrativo, no. 16 (December 15, 2016): 105. http://dx.doi.org/10.18601/21452946.n16.07.

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La que podemos denominar “administración pública” de la época republicana romana se caracterizaba por su adaptación a las siguientes reglas: temporalidad limitada en el ejercicio de los cargos públicos, elección popular de sus titulares, gratuidad en su desempeño, pluralidad de titulares para un mismo cargo y colegialidad entre ellos, ausencia de jerarquía y autonomía e independencia de cada titular, carga personal en los gastos causados en el ejercicio de los cargos públicos. El régimen imperial introdujo las reglas exactamente contrarias. Si se tiene presente que estas reglas contrarias aún
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Nie, Chao, Huimin Wang, Rui Wang, David Ginsburg, and Xiao-Wei Chen. "Dimeric sorting code for concentrative cargo selection by the COPII coat." Proceedings of the National Academy of Sciences 115, no. 14 (2018): E3155—E3162. http://dx.doi.org/10.1073/pnas.1704639115.

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The flow of cargo vesicles along the secretory pathway requires concerted action among various regulators. The COPII complex, assembled by the activated SAR1 GTPases on the surface of the endoplasmic reticulum, orchestrates protein interactions to package cargos and generate transport vesicles en route to the Golgi. The dynamic nature of COPII, however, hinders analysis with conventional biochemical assays. Here we apply proximity-dependent biotinylation labeling to capture the dynamics of COPII transport in cells. When SAR1B was fused with a promiscuous biotin ligase, BirA*, the fusion protei
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11

Ayantoyinbo, B. B., and A. E. Gbadegesin. "Examination of the Characteristics of Air Cargo Delivery in Nigeria." Journal of Transportation Engineering and Traffic Management 3, no. 2 (2022): 1–9. https://doi.org/10.5281/zenodo.6965807.

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Air transportation is the fastest means of conveying cargo from one place to another, most especially over long distance. However, majority of research in this area have concentrated on passenger satisfaction, while not much research has been carried out on efficiency of air cargo delivery in Nigeria. Therefore, this study assessed the characteristics of air cargo delivery in Nigeria. The study was carried out at the cargo terminal of Murtala Muhammed International Airport, Lagos State, Nigeria. Cochran’s formula was used to reduce the population to a sampling size of 239. Random samplin
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Chen, Yan, Jeffery Yong, Antonio Martínez-Sánchez, et al. "Dynamic instability of clathrin assembly provides proofreading control for endocytosis." Journal of Cell Biology 218, no. 10 (2019): 3200–3211. http://dx.doi.org/10.1083/jcb.201804136.

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Clathrin-mediated endocytosis depends on the formation of functional clathrin-coated pits that recruit cargos and mediate the uptake of those cargos into the cell. However, it remains unclear whether the cargos in the growing clathrin-coated pits are actively monitored by the coat assembly machinery. Using a cell-free reconstitution system, we report that clathrin coat formation and cargo sorting can be uncoupled, indicating that a checkpoint is required for functional cargo incorporation. We demonstrate that the ATPase Hsc70 and a dynamic exchange of clathrin during assembly are required for
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13

Iwata, Kakuya, and Osamu Matsum. "Aerial Cargo Robot (Cargo UAV)." Journal of Robotics and Mechatronics 26, no. 3 (2014): 394–95. http://dx.doi.org/10.20965/jrm.2014.p0394.

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<div class=""abs_img""><img src=""[disp_template_path]/JRM/abst-image/00260003/14.jpg"" width=""300"" /> Flight test of Cargo UAV</span></div> Safety is the most important factor in the civil use of aerial robots. Research on aerial cargo robots, also known as cargo unmanned aerial vehicles (UAV) started in 2004. The first ACR prototype flight was made on November 22, 2005. The ACR prototype consists of a flexible airfoil, twin microturbojet engines and a gravity center (GC) controller. The ACR meets the following four safety requirements: (i) touchability, i.e., withou
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14

Ren, Jihui, Younghoon Kee, Jon M. Huibregtse, and Robert C. Piper. "Hse1, a Component of the Yeast Hrs-STAM Ubiquitin-sorting Complex, Associates with Ubiquitin Peptidases and a Ligase to Control Sorting Efficiency into Multivesicular Bodies." Molecular Biology of the Cell 18, no. 1 (2007): 324–35. http://dx.doi.org/10.1091/mbc.e06-06-0557.

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Ubiquitinated integral membrane proteins are delivered to the interior of the lysosome/vacuole for degradation. This process relies on specific ubiquitination of potential cargo and recognition of that Ub-cargo by sorting receptors at multiple compartments. We show that the endosomal Hse1-Vps27 sorting receptor binds to ubiquitin peptidases and the ubiquitin ligase Rsp5. Hse1 is linked to Rsp5 directly via a PY element within its C-terminus and through a novel protein Hua1, which recruits a complex of Rsp5, Rup1, and Ubp2. The SH3 domain of Hse1 also binds to the deubiquitinating protein Ubp7.
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15

Rohde, David W. "Propensão ao risco e ambição progressiva: o caso dos deputados federais nos Estados Unidos." Revista Brasileira de Ciência Política, no. 8 (August 2012): 209–36. http://dx.doi.org/10.1590/s0103-33522012000200008.

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O artigo analisa a decisão dos membros da Câmara de Deputados dos Estados Unidos (House of Representatives) de concorrer ou não a um cargo superior (governador ou senador) durante o período de 1954 a 1974. O trabalho difere de análises anteriores sobre ambição por oferecer uma base teórica mais concreta para o estudo da ambição progressiva e tentar predizer quais deputados vão se candidatar a cargos superiores, mais do que apenas analisar as carreiras daqueles que o fizeram. Apresentam-se hipóteses que tratam da probabilidade de se eleger para o cargo superior, do valor deste cargo, do valor d
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Cazelato de Souza, Débora. "Não poderá o juiz de fora servir os três lugares”: a criação do juizado de órfãos em Salvador (1725)." Temas Americanistas, no. 47 (2021): 217–30. http://dx.doi.org/10.12795/temas-americanistas.2021.i47.12.

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No ano de 1696 os juízes de fora foram criados em Salvador. Tais juízes exerciam concomitantemente três cargos. Diante das dificuldades da administração da justiça, em 1725, D. João V instalou o cargo de juízes de órfãos em separado dos juízes forâneos. Portanto, percebe-se que a instalação deste cargo não se deu devido uma queixa direta aos ministros e sim ao acúmulo excessivo de trabalho.
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17

Korovyakovskiy, Evgeny, and Mardonbek Saburov. "Ways to a Rise Efficiency of Logistic Provision for International Transport System “Agroexpress” Activity on the Basis of One-Criterion Optimization." Proceedings of Petersburg Transport University 19, no. 2 (2022): 276–85. http://dx.doi.org/10.20295/1815-588x-2022-19-2-276-285.

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Purpose: To develop technology variants to provide for necessary level of cargo traffic for trains “Agroexpress” and mathematical model proposal for these purposes. Methods: System analysis, operation mathematical optimization and linear programming. Results: Work flows on provision of agricultural cargos of the being considered train are analyzed. Mathematical model of provision of agro-production of “Agroexpress” trains in Uzbekistan is developed. With the help of the model, there is a possibility to improve work technology on provision of cargo traffic of “Agroexpress” in sufficient quantit
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KUZNETSOV, A. V. "MODELING OF ORGANELLE ENTRY IN AN AXON AND DENDRITE." Journal of Mechanics in Medicine and Biology 12, no. 05 (2012): 1250026. http://dx.doi.org/10.1142/s0219519412500261.

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The purpose of this paper is to develop a mathematical description of cargo transport in the entrance regions of axons and dendrites. The model accounts for the difference in microtubule (MT) orientation between axons and dendrites: axons have a uniform MT polarity orientation while dendrites have a mixed MT polarity orientation. Because of that, cargos pulled by dynein motors can enter dendrites but cannot enter axons. It is thus assumed that cargos are targeted to axons by associating them with kinesin motors and cargos are targeted to dendrites by associating them with dynein motors. Analyt
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Liu, Allen P., François Aguet, Gaudenz Danuser, and Sandra L. Schmid. "Local clustering of transferrin receptors promotes clathrin-coated pit initiation." Journal of Cell Biology 191, no. 7 (2010): 1381–93. http://dx.doi.org/10.1083/jcb.201008117.

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Clathrin-mediated endocytosis (CME) is the major pathway for concentrative uptake of receptors and receptor–ligand complexes (cargo). Although constitutively internalized cargos are known to accumulate into maturing clathrin-coated pits (CCPs), whether and how cargo recruitment affects the initiation and maturation of CCPs is not fully understood. Previous studies have addressed these issues by analyzing the global effects of receptor overexpression on CME or CCP dynamics. Here, we exploit a refined approach using expression of a biotinylated transferrin receptor (bTfnR) and controlling its lo
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Kohler, Stefan, Norman Sitali, and Nicolas Paul. "A Framework for Assessing Import Costs of Medical Supplies and Results for a Tuberculosis Program in Karakalpakstan, Uzbekistan." Health Data Science 2021 (August 26, 2021): 1–13. http://dx.doi.org/10.34133/2021/9813732.

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Background. Import of medical supplies is common, but limited knowledge about import costs and their structure introduces uncertainty to budget planning, cost management, and cost-effectiveness analysis of health programs. We aimed to estimate the import costs of a tuberculosis (TB) program in Uzbekistan, including the import costs of specific imported items. Methods. We developed a framework that applies costing and cost accounting to import costs. First, transport costs, customs-related costs, cargo weight, unit weights, and quantities ordered were gathered for a major shipment of medical su
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Gentry, Schuyler B., Scott J. Nowak, Xuelei Ni, et al. "A real-time assay for cell-penetrating peptide-mediated delivery of molecular cargos." PLOS ONE 16, no. 9 (2021): e0254468. http://dx.doi.org/10.1371/journal.pone.0254468.

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Cell-penetrating peptides (CPPs) are capable of transporting molecules to which they are tethered across cellular membranes. Unsurprisingly, CPPs have attracted attention for their potential drug delivery applications, but several technical hurdles remain to be overcome. Chief among them is the so-called ‘endosomal escape problem,’ i.e. the propensity of CPP-cargo molecules to be endocytosed but remain entrapped in endosomes rather than reaching the cytosol. Previously, a CPP fused to calmodulin that bound calmodulin binding site-containing cargos was shown to efficiently deliver cargos to the
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Yang, Weidong, та Siegfried M. Musser. "Nuclear import time and transport efficiency depend on importin β concentration". Journal of Cell Biology 174, № 7 (2006): 951–61. http://dx.doi.org/10.1083/jcb.200605053.

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Although many components and reaction steps necessary for bidirectional transport across the nuclear envelope (NE) have been characterized, the mechanism and control of cargo migration through nuclear pore complexes (NPCs) remain poorly understood. Single-molecule fluorescence microscopy was used to track the movement of cargos before, during, and after their interactions with NPCs. At low importin β concentrations, about half of the signal-dependent cargos that interacted with an NPC were translocated across the NE, indicating a nuclear import efficiency of ∼50%. At high importin β concentrat
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Ni, Kareemah, Chenghao Wang, Jonathan M. Carnino, and Yang Jin. "The Evolving Role of Caveolin-1: A Critical Regulator of Extracellular Vesicles." Medical Sciences 8, no. 4 (2020): 46. http://dx.doi.org/10.3390/medsci8040046.

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Emerging evidence suggests that extracellular vesicles (EVs) play an essential role in mediating intercellular communication and inter-organ crosstalk both at normal physiological conditions and in the pathogenesis of human diseases. EV cargos are made up of a broad spectrum of molecules including lipids, proteins, and nucleic acids such as DNA, RNA, and microRNAs. The complex EV cargo composition is cell type-specific. A dynamic change in EV cargos occurs along with extracellular stimuli and a change in the pathophysiological status of the host. Currently, the underlying mechanisms by which E
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Destombes, Christelle. "cargo." Vacarme 4 - 5, no. 4 (1997): 19. http://dx.doi.org/10.3917/vaca.004.0019.

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Galin, A. V., P. S. Rudny, and K. A. Galin. "Monte-Carlo analysis model for evaluation of container terminal parameters." Vestnik Gosudarstvennogo universiteta morskogo i rechnogo flota imeni admirala S. O. Makarova 16, no. 6 (2025): 837–46. https://doi.org/10.21821/2309-5180-2024-16-6-837-846.

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This paper considers using Monte-Carlo analysis method for evaluation some of the parameters of a container terminal. A high amount of scientific work on this topic is noted in domestic literature. International scientific literature concerning usage of Monte-Carlo method for simulating different parameters of container terminals is also analyzed. We note that foreign authors often use Monte-Carlo analysis as an auxiliary method, for example, for checking results of discrete-event simulation model of a complicated logistical system for adequacy, whereas domestic authors often use Monte-Carlo a
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Saraogi, Ishu, David Akopian, and Shu-ou Shan. "Regulation of cargo recognition, commitment, and unloading drives cotranslational protein targeting." Journal of Cell Biology 205, no. 5 (2014): 693–706. http://dx.doi.org/10.1083/jcb.201311028.

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Efficient and accurate protein localization is essential to cells and requires protein-targeting machineries to both effectively capture the cargo in the cytosol and productively unload the cargo at the membrane. To understand how these challenges are met, we followed the interaction of translating ribosomes during their targeting by the signal recognition particle (SRP) using a site-specific fluorescent probe in the nascent protein. We show that initial recruitment of SRP receptor (SR) selectively enhances the affinity of SRP for correct cargos, thus committing SRP-dependent substrates to the
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vom Saal, Robert J., Igor Mizine, Laurent C. Deschamps, and Richard W. Thorpe. "Dual-Use Short Sea Shipping Trimaran Trailership HSTT-180." Marine Technology and SNAME News 42, no. 03 (2005): 132–43. http://dx.doi.org/10.5957/mt1.2005.42.3.132.

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This paper describes the concept design of a high-speed trimaran roll-on/roll-off (RO/RO) designed for commercial cargo but readily convertible to military use. It is designed for a coastal express service, such as Port Canaveral, Florida, to Wilmington, Delaware, so the emphasis is on speed, simplicity, and reliability. All the RO/RO cargo is carried on the main deck, and there is room for a limited number of passengers to accompany their cargos.
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Surovtsev, Ivan V., Manuel Campos, and Christine Jacobs-Wagner. "DNA-relay mechanism is sufficient to explain ParA-dependent intracellular transport and patterning of single and multiple cargos." Proceedings of the National Academy of Sciences 113, no. 46 (2016): E7268—E7276. http://dx.doi.org/10.1073/pnas.1616118113.

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Spatial ordering of macromolecular components inside cells is important for cellular physiology and replication. In bacteria, ParA/B systems are known to generate various intracellular patterns that underlie the transport and partitioning of low-copy-number cargos such as plasmids. ParA/B systems consist of ParA, an ATPase that dimerizes and binds DNA upon ATP binding, and ParB, a protein that binds the cargo and stimulates ParA ATPase activity. Inside cells, ParA is asymmetrically distributed, forming a propagating wave that is followed by the ParB-rich cargo. These correlated dynamics lead t
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Katin, Viktor, Vladimir Kosygin, Midkhat Akhtiamov, and Andrey Lutsenko. "Elaboration and model analysis of characteristics of the flexible liner for an oil tank car." MATEC Web of Conferences 239 (2018): 01030. http://dx.doi.org/10.1051/matecconf/201823901030.

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The article focuses on the original author's development – the flexible liner for a rail tank car that allows reducing the risk of leakage of hazardous liquid cargos (in particular crude oil or petroleum products) during their transportation by rail. Application of the liner allows ensuring hermetical containment of a tank car even if a barrel has any minor defects, excludes a contact of cargo with tank walls, which leads to increase in the security of hazardous liquid cargo transportation. This original development enables ensuring the safety and security of hazardous cargo transportation and
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Coradini, Odaci Luiz. "Categorias sócio-profissionais, titulação escolar e disputas eleitorais." Revista de Sociologia e Política 20, no. 41 (2012): 109–22. http://dx.doi.org/10.1590/s0104-44782012000100008.

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O artigo expõe resultados da análise das relações entre recursos de posição social, investimentos financeiros em campanhas e resultados em disputas eleitorais de diferentes níveis. Foram incluídos os candidatos às eleições municipais de 2004 e gerais de 2006. No que tange aos recursos de posição social, foram examinadas particularmente as associações com a condição profissional e com a titulação escolar. Foram examinados também os efeitos da ocupação prévia de cargos eletivos. Conforme a hipótese geral perseguida, por um lado, ocorre um processo de concentração nas categorias ocupacionais que
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Ponte, Luiz Eduardo de Paula. "Breve ensaio acerca da posse em cargo, função ou emprego público civil efetivo por militar." Revista Controle - Doutrina e Artigos 12, no. 1 (2014): 242–56. http://dx.doi.org/10.32586/rcda.v12i1.216.

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O presente artigo tem por objetivo analisar as consequências funcionais quando um agente público, investido em um cargo militar, toma posse também em um cargo, emprego ou função pública efetivo. Inicia-se buscando realizar uma leitura acerca das diferenças existentes entre os cargos marcial e civil, com o fito de demonstrar a necessidade de afastar a acumulação daquelas incumbências estatais. Após uma breve passagem pelo supedâneo constitucional que trata do tema, o próprio bloco de constitucionalidade pátrio nos traz as exceções à matéria, revelando-se, por fim, que a jurisprudência vem pacif
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De Mello, Celso. "Cargo público - Brasileiro naturalizado - Português." Revista de Direito Administrativo 185 (July 1, 1991): 181–84. http://dx.doi.org/10.12660/rda.v185.1991.44585.

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- Cargos públicos privativos de brasileiros natos eram unicamente, no regime constitucional anterior, os relacionados, exaustivamente, no parágrafo único do art. 145 da Constituição de 1969.- Nos termos do Estatuto da Igualdade o português passa a ser tratado como se fosse brasileiro naturalizado.- Ao súdito português, equiparado a brasileiro naturalizado, não era defeso o cargo e posto de Oficial da Policia Militar.
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Sugawara, Takeshi, and Kunihiko Kaneko. "Chemophoresis engine: A general mechanism of ATPase-driven cargo transport." PLOS Computational Biology 18, no. 7 (2022): e1010324. http://dx.doi.org/10.1371/journal.pcbi.1010324.

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Cell polarity regulates the orientation of the cytoskeleton members that directs intracellular transport for cargo-like organelles, using chemical gradients sustained by ATP or GTP hydrolysis. However, how cargo transports are directly mediated by chemical gradients remains unknown. We previously proposed a physical mechanism that enables directed movement of cargos, referred to as chemophoresis. According to the mechanism, a cargo with reaction sites is subjected to a chemophoresis force in the direction of the increased concentration. Based on this, we introduce an extended model, the chemop
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Rueangkham, Naruemon, Miguel Valle-Inclán Cabello, Franziska Lautenschläger, and Rhoda J. Hawkins. "Nuclear deformation by microtubule molecular motors." PLOS Computational Biology 21, no. 5 (2025): e1012305. https://doi.org/10.1371/journal.pcbi.1012305.

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We present a model to calculate the displacement and extension of deformable cellular cargo pulled by molecular motors stepping along cytoskeletal filaments. We consider the case of a single type of molecular motor and cytoskeletal filaments oriented in one dimension in opposite directions on either side of a cargo. We model a deformable cargo as a simple elastic spring. We simulate this tug-of-war simple exclusion process model using a Monte Carlo Gillespie algorithm and calculate the displacement and extension of the cargo for different configurations of motors and filaments. We apply our mo
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Lima, Rafael Augusto Pereira, and Francisco Ricardo Duarte. "Regime jurídico administrativo dos servidores na PEC 32/2020." Revista de Gestão e Secretariado 15, no. 6 (2024): e3871. http://dx.doi.org/10.7769/gesec.v15i6.3871.

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O presente artigo analisa a Proposta de Emenda à Constituição (PEC) nº 32/2020, do Poder Executivo Federal, que propõe uma reforma administrativa no regime jurídico dos servidores públicos no Brasil. Para tanto, foi feito um estudo exploratório e descritivo, através da análise documental do Projeto de Emenda à Constituição nº 32/2020 e literaturas, artigos, painéis, decretos e leis em sites oficiais. A PEC introduz cinco modalidades de vínculo jurídico-administrativo: vínculo de experiência, vínculo por prazo determinado, cargo com vínculo por prazo indeterminado, cargo típico de Estado e carg
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PRAIYA, PANJEE, and AMORNSAWADWATANA SATAPORN. "CARGO INSURANCE IN THAILAND'S BORDER TRADE." Seybold Report Journal 18, no. 08 (2023): 1769–82. https://doi.org/10.5281/zenodo.8337331.

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<strong>Abstract</strong> To avoid the cargo damage during the transportation is one of the concerns for shippers and consignees. Since cargo damage not only results in the loss of valuable goods but also define significant financial, temporal, and resource burdens on the transporting company. Addressing damaged goods need the collaboration with insurance providers to recuperate losses, a process that can be time-consuming and resource intensive. As such, a proactive approach involving the procurement of insurance coverage prior to the commencement of cargo transportation is highly advisable.
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Nazarko, Taras Y., Jean-Claude Farré, and Suresh Subramani. "Peroxisome Size Provides Insights into the Function of Autophagy-related Proteins." Molecular Biology of the Cell 20, no. 17 (2009): 3828–39. http://dx.doi.org/10.1091/mbc.e09-03-0221.

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Autophagy is a major pathway of intracellular degradation mediated by formation of autophagosomes. Recently, autophagy was implicated in the degradation of intracellular bacteria, whose size often exceeds the capacity of normal autophagosomes. However, the adaptations of the autophagic machinery for sequestration of large cargos were unknown. Here we developed a yeast model system to study the effect of cargo size on the requirement of autophagy-related (Atg) proteins. We controlled the size of peroxisomes before their turnover by pexophagy, the selective autophagy of peroxisomes, and found th
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Hao, Chan. "Simulation of the duration of cargo operations at the stations on the route of Groupaged block container train." Herald of the Ural State University of Railway Transport, no. 4 (2021): 111–17. http://dx.doi.org/10.20291/2079-0392-2021-4-111-117.

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The article is devoted to modelling the duration of cargo operations at intermediate stations on the route of a modular express freight container train (MEFCT), that is, a train with a fixed schedule heading from the initial to the final station without remarshalling a rolling-stock, but performing the cargo handling operations for loading/unloading of containers at intermediate stops on the route. Cargo handling operations at intermediate stations of a MEFCT entail a non-productive run of a loader along the train from one container to be reloaded to the other. In the case of a random placemen
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Sabaydash, Marina Vladislavovna. "Retrospective analysis of commercial sea ports operation during first five-year plans and their role in USSR economic industrialization (1928-1940)." Vestnik of Astrakhan State Technical University. Series: Economics 2020, no. 4 (2020): 83–97. http://dx.doi.org/10.24143/2073-5537-2020-4-83-97.

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The article highlights the general regularities of the economic development of commercial sea ports in the USSR and defines their role in industrialization of the country. For the first time there has been carried out a comparative analysis of sea port cargo turnover dynamics in relation to the ports of Great Britain, Germany, Italy, the Netherlands, the USA and France. The rates of port cargo turnover growth are investigated in comparison with the rates of industrial production growth, the volume of railway and inland water transport. The changes in the main cargo flows connected to the indus
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Husiatyńska, Renata. "Cargo insurance in maritime transportation." Zeszyty Naukowe Uniwersytetu Szczecińskiego Problemy Transportu i Logistyki 42 (2018): 29–37. http://dx.doi.org/10.18276/ptl.2018.42-03.

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Lam, Vinh Q., David Akopian, Michael Rome, Doug Henningsen, and Shu-ou Shan. "Lipid activation of the signal recognition particle receptor provides spatial coordination of protein targeting." Journal of Cell Biology 190, no. 4 (2010): 623–35. http://dx.doi.org/10.1083/jcb.201004129.

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The signal recognition particle (SRP) and SRP receptor comprise the major cellular machinery that mediates the cotranslational targeting of proteins to cellular membranes. It remains unclear how the delivery of cargos to the target membrane is spatially coordinated. We show here that phospholipid binding drives important conformational rearrangements that activate the bacterial SRP receptor FtsY and the SRP–FtsY complex. This leads to accelerated SRP–FtsY complex assembly, and allows the SRP–FtsY complex to more efficiently unload cargo proteins. Likewise, formation of an active SRP–FtsY GTPas
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Mr., Nguyen Hai Quang*. "CONTRIBUTION OF AIR CARGO TRANSPORT AND AIR CARGO SERVICES TO GDP IN VIETNAM." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 6, no. 9 (2017): 514–19. https://doi.org/10.5281/zenodo.995977.

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This study aims to determine the contribution of air cargo transport and air cargo services to Gross Domestic Product (GDP) in Vietnam. These are the two major areas that make up the value of logistics in the air transport sector. Through the development of methodology and data collection for the six years from 2011 to 2016, the analysis results show that the contribution of air cargo transport and air cargo services to GDP in Vietnam has increased on average is 10.78% per year, nearly double the GDP growth rate of Vietnam. Although their share in GDP is still small but it is increasing and be
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Marric, Linda. "Unwanted cargo." New Scientist 250, no. 3334 (2021): 33. http://dx.doi.org/10.1016/s0262-4079(21)00838-1.

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Kirkpatrick, Peter. "Deadly cargo." Nature Reviews Drug Discovery 1, no. 8 (2002): 568. http://dx.doi.org/10.1038/nrd881.

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Roberts, Jennifer L. "Copley's Cargo." American Art 21, no. 2 (2007): 20–41. http://dx.doi.org/10.1086/521888.

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Ralph, Laurence. "Black cargo." HAU: Journal of Ethnographic Theory 10, no. 2 (2020): 269–78. http://dx.doi.org/10.1086/710167.

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Williams, Elliot C., Raul Coimbra, Theresa W. Chan, Andrew Baird, Brian P. Eliceiri, and Todd W. Costantini. "Precious cargo." Journal of Trauma and Acute Care Surgery 86, no. 1 (2019): 52–61. http://dx.doi.org/10.1097/ta.0000000000002093.

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Tigchelaar, Jana. "Precious Cargo." Mark Twain Annual 22 (December 2024): 155–58. https://doi.org/10.5325/marktwaij.22.1.0155.

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Tan, Anthony L. "The Cargo." Manoa 15, no. 1 (2003): 170–80. http://dx.doi.org/10.1353/man.2003.0111.

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Kadri, Kathie. "Precious Cargo." Annals of Internal Medicine 137, no. 4 (2002): 291. http://dx.doi.org/10.7326/0003-4819-137-4-200208200-00016.

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