Relevant bibliographies by topics / Cardiovascular fluid mechanic

Academic literature on the topic 'Cardiovascular fluid mechanic'

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Published: 14 March 2023

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Journal articles on the topic "Cardiovascular fluid mechanic"

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Oldenburg, Jan, Julian Renkewitz, Michael Stiehm, and Klaus-Peter Schmitz. "Contributions towards Data driven Deep Learning methods to predict Steady State Fluid Flow in mechanical Heart Valves." Current Directions in Biomedical Engineering 7, no. 2 (October 1, 2021): 625–28. http://dx.doi.org/10.1515/cdbme-2021-2159.

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Abstract It is commonly accepted that hemodynamic situation is related with cardiovascular diseases as well as clinical post-procedural outcome. In particular, aortic valve stenosis and insufficiency are associated with high shear flow and increased pressure loss. Furthermore, regurgitation, high shear stress and regions of stagnant blood flow are presumed to have an impact on clinical result. Therefore, flow field assessment to characterize the hemodynamic situation is necessary for device evaluation and further design optimization. In-vitro as well as in-silico fluid mechanics methods can be used to investigate the flow through prostheses. In-silico solutions are based on mathematical equitation’s which need to be solved numerically (Computational Fluid Dynamics - CFD). Fundamentally, the flow is physically described by Navier-Stokes. CFD often requires high computational cost resulting in long computation time. Techniques based on deep-learning are under research to overcome this problem. In this study, we applied a deep-learning strategy to estimate fluid flows during peak systolic steady-state blood flows through mechanical aortic valves with varying opening angles in randomly generated aortic root geometries. We used a data driven approach by running 3,500 two dimensional simulations (CFD). The simulation data serves as training data in a supervised deep learning framework based on convolutional neural networks analogous to the U-net architecture. We were able to successfully train the neural network using the supervised data driven approach. The results showing that it is feasible to use a neural network to estimate physiological flow fields in the vicinity of prosthetic heart valves (Validation error below 0.06), by only giving geometry data (Image) into the Network. The neural network generates flow field prediction in real time, which is more than 2500 times faster compared to CFD simulation. Accordingly, there is tremendous potential in the use of AIbased approaches predicting blood flows through heart valves on the basis of geometry data, especially in applications where fast fluid mechanic predictions are desired.
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Wiputra, Hadi, Ching Kit Chen, Elias Talbi, Guat Ling Lim, Sanah Merchant Soomar, Arijit Biswas, Citra Nurfarah Zaini Mattar, David Bark, Hwa Liang Leo, and Choon Hwai Yap. "Human fetal hearts with tetralogy of Fallot have altered fluid dynamics and forces." American Journal of Physiology-Heart and Circulatory Physiology 315, no. 6 (December 1, 2018): H1649—H1659. http://dx.doi.org/10.1152/ajpheart.00235.2018.

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Studies have suggested the effect of blood flow forces in pathogenesis and progression of some congenital heart malformations. It is therefore of interest to study the fluid mechanic environment of the malformed prenatal heart, such as the tetralogy of Fallot (TOF), especially when little is known about fetal TOF. In this study, we performed patient-specific ultrasound-based flow simulations of three TOF and seven normal human fetal hearts. TOF right ventricles (RVs) had smaller end-diastolic volumes (EDVs) but similar stroke volumes (SVs), whereas TOF left ventricles (LVs) had similar EDVs but slightly increased SVs compared with normal ventricles. Simulations showed that TOF ventricles had elevated systolic intraventricular pressure gradient (IVPG) and required additional energy for ejection but IVPG elevations were considered to be mild relative to arterial pressure. TOF RVs and LVs had similar pressures because of equalization via ventricular septal defect (VSD). Furthermore, relative to normal, TOF RVs had increased diastolic wall shear stresses (WSS) but TOF LVs were not. This was caused by high tricuspid inflow that exceeded RV SV, leading to right-to-left shunting and chaotic flow with enhanced vorticity interaction with the wall to elevate WSS. Two of the three TOF RVs but none of the LVs had increased thickness. As pressure elevations were mild, we hypothesized that pressure and WSS elevation could play a role in the RV thickening, among other causative factors. Finally, the endocardium surrounding the VSD consistently experienced high WSS because of RV-to-LV flow shunt and high flow rate through the over-riding aorta. NEW & NOTEWORTHY Blood flow forces are thought to cause congenital heart malformations and influence disease progression. We performed novel investigations of intracardiac fluid mechanics of tetralogy of Fallot (TOF) human fetal hearts and found essential differences from normal hearts. The TOF right ventricle (RV) and left ventricle had similar and elevated pressure but only the TOF RV had elevated wall shear stress because of elevated tricuspid inflow, and this may contribute to the observed RV thickening. TOF hearts also expended more energy for ejection.
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Kim, Youngho, and Sangho Yun. "Fluid Dynamics in an Anatomically Correct Total Cavopulmonary Connection : Flow Visualizations and Computational Fluid Dynamics(Cardiovascular Mechanics)." Proceedings of the Asian Pacific Conference on Biomechanics : emerging science and technology in biomechanics 2004.1 (2004): 57–58. http://dx.doi.org/10.1299/jsmeapbio.2004.1.57.

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Rajesh, Parvati. "Cardiovascular Biofluid Mechanics." International Journal of Innovative Science and Research Technology 5, no. 7 (July 16, 2020): 36–39. http://dx.doi.org/10.38124/ijisrt20jul186.

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This paper intends to study a real-life application of fluid mechanics in cardiovascular blood flow. The study of blood flow is termed as Hemodynamics. Fluid mechanics can be used to analyze the factors and impact of obstruction in blood flow due to fat, cholesterol, and plaque deposits in the coronary arteries of the human heart. These blockages are the grounds for coronary artery diseases and heart attacks. We will look at varying parameters of flowrate and pressure for different thicknesses of epicardial fat as well as define a relationship between these three.
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Nakamura, Masanori, Shigeo Wada, Daisuke Mori, Ken-ichi Tsubota, and Takami Yamaguchi. "Computational Fluid Dynamics Study of the Effect of the Left Ventricular Flow Ejection on the Intraaortic Flow(Cardiovascular Mechanics)." Proceedings of the Asian Pacific Conference on Biomechanics : emerging science and technology in biomechanics 2004.1 (2004): 61–62. http://dx.doi.org/10.1299/jsmeapbio.2004.1.61.

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Marusic, Ivan, and Susan Broomhall. "Leonardo da Vinci and Fluid Mechanics." Annual Review of Fluid Mechanics 53, no. 1 (January 5, 2021): 1–25. http://dx.doi.org/10.1146/annurev-fluid-022620-122816.

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This review focuses on Leonardo da Vinci's work and thought related to fluid mechanics as it is presented in a lifetime of notebooks, letters, and artwork. It shows how Leonardo's remaining works offer a complicated picture of unfinished, scattered, and frequently revisited hypotheses and conclusions. It argues that experimentation formed an important mechanism for Leonardo's thought about natural fluid flows, which was an innovation to the scientific thinking of his day, but which did not always lead him to the conclusions of modern fluid mechanics. It highlights the multiple and ambiguous meanings of turbulence in his works. It examines his thinking suggestive of modern concepts such as the no-slip condition, hydraulic jump, cardiovascular vortices, conservation of volume, and the distinctive path of ascending bubbles we now term Leonardo's paradox, among others. It demonstrates how Leonardo thought through analogies, building-block flow patterns, and synthesis, leading both to successes—especially in the management of water—and to failures, perhaps most obviously in his pursuit of human flight.
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Guala, Andrea, Michele Scalseggi, and Luca Ridolfi. "Coronary fluid mechanics in an ageing cardiovascular system." Meccanica 52, no. 3 (October 5, 2015): 503–14. http://dx.doi.org/10.1007/s11012-015-0283-0.

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Taylor, Charles A., and Mary T. Draney. "EXPERIMENTAL AND COMPUTATIONAL METHODS IN CARDIOVASCULAR FLUID MECHANICS." Annual Review of Fluid Mechanics 36, no. 1 (January 2004): 197–231. http://dx.doi.org/10.1146/annurev.fluid.36.050802.121944.

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Dasi, Lakshmi P., Philippe Sucosky, Diane De Zelicourt, Kartik Sundareswaran, Jorge Jimenez, and Ajit P. Yoganathan. "Advances in Cardiovascular Fluid Mechanics: Bench to Bedside." Annals of the New York Academy of Sciences 1161, no. 1 (April 2009): 1–25. http://dx.doi.org/10.1111/j.1749-6632.2008.04320.x.

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Lee, Sang-Hyun. "NUMERICAL MODELING OF FLUID-STRUCTURE INTERACTIONS IN CARDIOVASCULAR MECHANICS." Journal of Computational Fluids Engineering 22, no. 2 (June 30, 2017): 1–14. http://dx.doi.org/10.6112/kscfe.2017.22.2.001.

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Dissertations / Theses on the topic "Cardiovascular fluid mechanic"

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Rose, Michael Leon James. "Development of a muscle powered blood pump fluid mechanic considerations /." Thesis, Connect to electronic version, 1998. http://hdl.handle.net/1905/190.

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Thesis (Ph. D.)--University of Glasgow, 1998.
Thesis submitted to the Department of Cardiac Surgery, Faculty of Medicine, University of Glasgow, in fulfilment of the degree of Doctor of Philosophy. Print version also available.
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Subramaniam, Dhananjay Radhakrishnan. "Role of Elasticity in Respiratory and Cardiovascular Flow." University of Cincinnati / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1522054562050044.

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Bottom, Karen Evelyn 1975. "A numerical model of cardiovascular fluid mechanics during external cardiac assist." Thesis, Massachusetts Institute of Technology, 1999. http://hdl.handle.net/1721.1/9405.

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Yousefi, Koupaei Atieh. "Biomechanical Interaction Between Fluid Flow and Biomaterials: Applications in Cardiovascular and Ocular Biomechanics." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1595335168435434.

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Ge, Liang. "Numerical Simulation of 3D, Complex, Turbulent Flows with Unsteady Coherent Structures: From Hydraulics to Cardiovascular Fluid Mechanics." Diss., Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-11162004-125756/unrestricted/ge%5Fliang%5F200412%5Fphd.pdf.

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Thesis (Ph. D.)--Civil and Environmental Engineering, Georgia Institute of Technology, 2005.
Yoganathan, Ajit, Committee Member ; Sturm, Terry, Committee Member ; Webster, Donald, Committee Member ; Roberts, Philip, Committee Member ; Sotiropoulos, Fotis, Committee Chair ; Fritz, Hermann, Committee Member. Includes bibliographical references.
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Salman, Huseyin Enes. "Investigation Of Fluid Structure Interaction In Cardiovascular System From Diagnostic And Pathological Perspective." Master's thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614388/index.pdf.

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Atherosclerosis is a disease of the cardiovascular system where a stenosis may develop in an artery which is an abnormal narrowing in the blood vessel that adversely affects the blood flow. Due to the constriction of the blood vessel, the flow is disturbed, forming a jet and recirculation downstream of the stenosis. Dynamic pressure fluctuations on the inner wall of the blood vessel leads to the vibration of the vessel structure and acoustic energy is propagated through the surrounding tissue that can be detected on the skin surface. Acoustic energy radiating from the interaction of blood flow and stenotic blood vessel carries valuable information from a diagnostic perspective. In this study, a constricted blood flow is modeled by using ADINA finite element analysis software together with the blood vessel in the form of a thin cylindrical shell with an idealized blunt constriction. The flow is considered as incompressible and Newtonian. Water properties at indoor temperature are used for the fluid model. The diameter of the modeled vessel is 6.4 mm with 87% area reduction at the throat of the stenosis. The flow is investigated for Reynolds numbers 1000 and 2000. The problem is handled in three parts which are rigid wall Computational Fluid Dynamics (CFD) solution, structural analysis of fluid filled cylindrical shell, and Fluid Structure Interaction (FSI) solutions of fluid flow and vessel structure. The pressure fluctuations and consequential vessel wall vibrations display broadband spectral content over a range of several hundred Hz with strong fluid-structural coupling. Maximum dynamic pressure and vibration amplitudes are observed around the reattachment point of the flow near the exit of the stenosis and this effect gradually decreases along downstream of flow. Results obtained by the numerical simulations are compared with relevant studies in the literature and it is concluded that ADINA can be used to investigate these types of problems involving high frequency pressure fluctuations of the fluid and the resulting vibratory motion of the surrounding blood vessel structure.
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Fan, Yi, and 樊怡. "The applications of computational fluid dynamics to the cardiovascularsystem and the respiratory system." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47753195.

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The diseases of cardiovascular system and the respiratory system have been the second and third killers causing deaths in Hong Kong. In this stressful civilized world, the prevalence and incidence of these diseases increased prominently which arouse our concern on the theories behind the pathological conditions. This report will focus on the biofluid mechanics in the large artery and in the upper airway. Thoracic aortic dissection, characterized by the tearing in the middle layer of vessel wall, is a catastrophic vascular disorder. The wall of the newly formed channel, the false lumen, is weakened and prone to aortic events. Endovascular repair is a minimally invasive technique for treating dissection patients. The biomechanical factors and the length of endograft were studied by computational fluid dynamics. Two geometrical factors showed a significant impact on the backflow in the false lumen. A larger false lumen and a larger distal tear size greatly affected the extent of thrombosis in the false lumen. It made the false lumen under a higher risk of vessel rupture. The computational prediction also demonstrated a more stable hemodynamic condition in the model with a longer endograft. These results provide important information for the clinicians to propose the surgical procedures and to improve the design of endografts. Airway obstruction is a common breathing disorder but it is always underdiagnosed. Obstructive sleep apnea (OSA) and different dentofacial deformities are two pathological conditions in which the patients have the abnormal sizes of airways. Computational fluid dynamic was employed in both conditions with patient–specific models. In the part of OSA, pre– and post–operative models were studied. The dimensions and flow resistance of the upper airway showed a significant improvement after mandibular distraction. The percentage of stenosis and the flow resistance was reduced by 27.3% and 40.7% respectively. For the patients in three facial skeletal deformity groups, the cross–sectional area and the flow resistance were compared. The patients with Class II deformity had the smallest retroglossal and retroplatal dimensions as well as the greatest flow resistance. The results confirmed the effectiveness of mandibular distraction and also provide valuable implications for the clinicians on the treatment planning, particularly for the Class II subjects.
published_or_final_version
Mechanical Engineering
Master
Master of Philosophy
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Doyle, Matthew Gerard. "Simulation of Myocardium Motion and Blood Flow in the Heart with Fluid-Structure Interaction." Thesis, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/20166.

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The heart is a complex organ and much is still unknown about its mechanical function. In order to use simulations to study heart mechanics, fluid and solid components and their interaction should be incorporated into any numerical model. Many previous studies have focused on myocardium motion or blood flow separately, while neglecting their interaction. Previous fluid-structure interaction (FSI) simulations of heart mechanics have made simplifying assumptions about their solid models, which prevented them from accurately predicting the stress-stain behaviour of the myocardium. In this work, a numerical model of the canine left ventricle (LV) is presented, which serves to address the limitations of previous studies. A canine LV myocardium material model was developed for use in conjunction with a commercial finite element code. The material model was modified from its original form to make it suitable for use in simulations. Further, numerical constraints were imposed when calculating the material parameter values, to ensure that the model would be strictly convex. An initial geometry and non-zero stress state are required to start cardiac cycle simulations. These were generated by the static inflation of a passive LV model to an end-diastolic pressure. Comparisons with previous measurements verified that the calculated geometry was representative of end diastole. Stresses calculated at the specified end diastolic pressure showed complex spatial variations, illustrating the superiority of the present approach over a specification of an arbitrary stress distribution to an end-diastolic geometry. In the third part of this study, FSI simulations of the mechanics of the LV were performed over the cardiac cycle. Calculated LV cavity pressures agreed well with previous measurements during most of the cardiac cycle, but deviated from them during rapid filling, which resulted in non-physiological backflow. This study is the first one to present a detailed analysis of the temporal and spatial variations of the properties of both the solid and the fluid components of the canine LV. The observed development of non-uniform pressure distributions in the LV cavity confirms the advantage of performing FSI simulations rather than imposing a uniform fluid pressure on the inner surface of the myocardium during solid-only simulations.
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Restrepo, Pelaez Maria. "Development of a coupled geometrical multiscale solver and application to single ventricle surgical planning." Diss., Georgia Institute of Technology, 2015. http://hdl.handle.net/1853/54832.

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Single ventricle heart defects are present in two of every 1000 live births in the US. In this condition the systemic and pulmonary blood flow mix in the functioning ventricle, resulting in insufficient blood oxygenation to sustain life. As part of the palliation of these defects, the staged surgical procedure, known as the Fontan procedure, is performed. Here, the venous returns are directed to the pulmonary arteries, bypassing the right heart and forming the Total Cavopulmonary Connection (TCPC). Even though the palliation improves life expectancy, there are numerous long-term complications that become more prevalent as patients reach adulthood. Many of these complications have been related to the function of the single ventricle circulation, especially to the abnormal TCPC hemodynamics, for which this has been the focus of research throughout the years. Recent progress has been made with the availability of improved medical imaging techniques and computational modeling tools; however, there is limited information on how these evolve in time. In order to improve the Fontan palliation, image-based surgical planning has been used in the most complex cases to prospectively design the TCPC, aiming to improve the hemodynamics. Even though this paradigm has shown promising results, improvement is needed to provide more realistic predictions of the post-operative outcomes. To address this, in this thesis we have developed a novel surgical planning framework that allows us to: (i) model the interaction of the TCPC and global circulation hemodynamics, and (ii) assess the robustness of the surgical option proposed. Here, the single ventricle circulation is modeled using a lumped parameter model, coupled to a computational fluid solver to describe the local TCPC hemodynamics. With this framework, we can predict the immediate post-operative state, model various physiological scenarios, and assess the impact on the local hemodynamics and global circulation. This will allow us to provide information on the effect on the global hemodynamics to the clinical team. In addition to the surgical planning advancements obtained in this thesis, we have performed the largest longitudinal Fontan study to date in which we have evaluated the evolution of the Fontan physiology in time and the effect it has on the energy efficiency of the TCPC. In this thesis, we have studied the short and long-term effects that geometrical and physiological changes have on the Fontan hemodynamics. With this, we have improved the understanding of the Fontan physiology in terms of the short-term effects of Fontan palliation and the long-term deterioration of the changing single ventricle physiology.
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Martorell, López Jordi. "Correlation between cardiovascular disease biomarkers and biochemical and physical milieu in complex vascular environments." Doctoral thesis, Universitat Ramon Llull, 2013. http://hdl.handle.net/10803/125238.

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La progressió de l'aterosclerosi i la trombosi en pacients amb risc de malaltia cardiovascular depèn en gran mesura de l'entorn únic a nivell físic i bioquímic cada individu. Característiques tals com l'arquitectura de la vasculatura, la composició bioquímica de la sang o el tipus de tractament defineixen el resultat de les intervencions cardiovasculars. La col•locació d'un stent o d'un bypass busca recuperar la permeabilitat del vas, però es veu limitada per la restenosis i la trombosi. El disseny de models multi-escala específics per a cada pacient pot ajudar a entendre la progressió d'aquests esdeveniments en tenir la capacitat per integrar les respostes cel•lulars microscòpiques en el context del flux macroscòpic i de les condicions estructurals. Aquests models poden proporcionar informació sobre com mitigar respostes adverses en funció de cada individu. Emprant mètodes in silico i in vitro prèviament validats, s'ha desenvolupat una plataforma de replicació arterial per reproduir bifurcacions vasculars coronàries i caròtides derivades d'imatges clíniques que s'han fet servir per generar arxius computacionals per a anàlisi in silico per una banda i per fabricar models arterials polimèrics biocompatibles per a anàlisis in vitro de l’altra. En paral•lel amb les simulacions de flux, els models físics van ser sembrats amb cèl•lules vasculars centrals en l'hemostàsia i la resposta a les lesions. Els models vasculars van ser exposats a fluxos fisiològics rellevants i a entorns urèmics, inflamatoris o anti-proliferatius. Després de la caracterització funcional dels models, el progrés de l'aterosclerosi i la trombosi es va quantificar a nivell local i es va correlacionar amb les característiques biològiques, químiques i físiques de l'entorn cel•lular. La quantitat de recirculació i la presència d'agents inflamatoris, productes químics anti proliferatius i de sèrum i soluts urèmics van ser crítics per a l'activació dels biomarcadors d'evolució d'aterosclerosi i trombosi . Plataformes integrades tals com la descrita en aquesta tesi podrien ser molt útils en una varietat de camps de la biomedicina. La plataforma pot ajudar els investigadors a respondre una sèrie de qüestions biològiques clínicament rellevants i té la capacitat de produir empelts vasculars bioimplantables en un futur pròxim.
La progresión de la aterosclerosis y la trombosis en pacientes con riesgo de enfermedad cardiovascular depende en gran medida del entorno único a nivel físico y bioquímico de cada individuo. Características tales como la arquitectura de la vasculatura, composición bioquímica de la sangre o el tipo de tratamiento definen el resultado de las intervenciones cardiovasculares. La colocación de un stent o de un bypass busca recuperar la permeabilidad del vaso, pero se ve limitada por la restenosis y la trombosis. El diseño de modelos multi-escala específicos para cada paciente puede ayudar a entender la progresión de estos eventos al tener capacidad para integrar las respuestas celulares microscópicas en el contexto del flujo macroscópico y de las condiciones estructurales. Dichos modelos pueden proporcionar información sobre cómo mitigar respuestas adversas en función de cada individuo. Usando métodos in silico e in vitro previamente validados se ha desarrollado una plataforma de replicación arterial para reproducir bifurcaciones vasculares coronarias y carótidas derivadas de imágenes clínicas, que se han usado para generar archivos computacionales para análisis in silico por un lado y para fabricar modelos arteriales poliméricos biocompatibles para análisis in vitro por otro. En paralelo con las simulaciones de flujo, los modelos físicos fueron sembrados con células vasculares centrales en la hemostasia y la respuesta a las lesiones. Los modelos vasculares fueron expuestos a flujos fisiológicos relevantes y a entornos urémicos, inflamatorios o anti proliferativos. Tras la caracterización funcional de los modelos, el progreso de la aterosclerosis y la trombosis se cuantificó a nivel local y se correlacionó con las características biológicas, químicas y físicas del entorno celular. La cantidad de recirculación y la presencia de agentes inflamatorios, productos químicos anti proliferativos y de suero y solutos urémicos fueron críticos para la activación de los biomarcadores de evolución de aterosclerosis y trombosis. Plataformas integradas tales como la descrita en esta tesis podrían ser muy útiles en una variedad de campos de la biomedicina. La plataforma puede ayudar a los investigadores a responder una serie de cuestiones biológicas clínicamente relevantes y tiene la capacidad de producir injertos vasculares bioimplantables en un futuro próximo.
Progression of atherosclerosis and thrombosis in patients at risk of cardiovascular disease depend heavily upon the unique physical and biochemical environment of each individual. Characteristics such as vessel architecture, biochemical composition of blood or type of treatment define the outcome of cardiovascular interventions. Stent placement and graft positioning seek to recover vessel patency, yet are limited by restenosis and thrombosis. Composite, patient-specific, multi-scale models able to integrate microscopic cellular responses in the context of relevant macroscopic flow and structural conditions may help understand the progression of these events, providing insight into how to mitigate adverse responses in specific settings and individuals. Based on previously validated in silico and in vitro methods, an arterial replication platform was developed. Vascular architectures from coronary and carotid bifurcations were derived from clinical imaging and used to generate conjoint computational meshing for in silico analysis and polymeric, biocompatible scaffolds for in vitro models. In parallel with three dimensional flow simulations, the geometrically-realistic constructs were seeded with vascular cells critical to vessel hemostasis and response to injury and exposed to relevant, physiologic flows and uremic, inflammatory or anti-proliferative conditions. Following functional characterization, in vitro surrogates of atherosclerotic and thrombogenic progression were locally quantified and correlated with the biological, chemical and physical characteristics of the cellular environment. The extent of recirculation and the presence of inflammatory agents, anti-proliferative chemicals and uremic serum and solutes were critical to the activation of atherosclerosis and thrombosis progression biomarkers. Integrated frameworks such as the one described in this thesis could be very useful in a range of biomedical fields. The platform may help researchers to answer an array of biological and clinically relevant questions and holds the capacity to cast bioimplantable vascular grafts in a close future.
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Books on the topic "Cardiovascular fluid mechanic"

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Pedrizzetti, Gianni, and Karl Perktold, eds. Cardiovascular Fluid Mechanics. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-2542-7.

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Waite, Lee. Biofluid mechanics in cardiovascular systems. New York: McGraw-Hill, 2006.

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Pedrizzetti, Gianni. Fluid Mechanics for Cardiovascular Engineering. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-85943-5.

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P, Verdonck, and Perktold K, eds. Intra and extracorporeal cardiovascular fluid dynamics. Southampton: Computational Mechanics Publications, 1998.

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Yoganathan, A. P. (Ajit Prithiviraj), 1951- and Rittgers Stanley E. 1947-, eds. Biofluid mechanics: The human circulation. 2nd ed. Boca Raton: Taylor & Francis, 2012.

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1947-, Rittgers Stanley E., and Yoganathan A. P. 1951-, eds. Biofluid mechanics: The human circulation. Boca Raton: CRC/Taylor & Francis, 2007.

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B, Lumsden Alan, Kline William E. 1948-, Kakadiaris Ioannis A, and SpringerLink (Online service), eds. Pumps and Pipes: Proceedings of the Annual Conference. Boston, MA: Springer Science+Business Media, LLC, 2011.

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Hayashi, K., Hiroyuki Abe, and Sato M. Data book on mechanical properties of living cells, tissues, and organs. Tokyo: Springer, 1996.

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Thiriet, Marc. Tissue Functioning and Remodeling in the Circulatory and Ventilatory Systems. New York, NY: Springer New York, 2013.

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Pedrizzetti, Gianni, and Karl Perktold. Cardiovascular Fluid Mechanics. Springer London, Limited, 2014.

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Book chapters on the topic "Cardiovascular fluid mechanic"

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Kheradvar, Arash, and Gianni Pedrizzetti. "Fundamental Fluid Mechanics." In Vortex Formation in the Cardiovascular System, 1–16. London: Springer London, 2011. http://dx.doi.org/10.1007/978-1-4471-2288-3_1.

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Pedley, Timothy J. "Arterial and Venous Fluid Dynamics." In Cardiovascular Fluid Mechanics, 1–72. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-2542-7_1.

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Perktold, Karl, and Martin Prosi. "Computational Models of Arterial Flow and Mass Transport." In Cardiovascular Fluid Mechanics, 73–136. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-2542-7_2.

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Tsangaris, Sokrates, and Theodora Pappou. "Finite Difference and Finite Volume Techniques for the Solution of Navier-Stokes Equations in Cardiovascular Fluid Mechanics." In Cardiovascular Fluid Mechanics, 137–86. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-2542-7_3.

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Pedrizzetti, Gianni, and Federico Domenichini. "Fluid Flow inside Deformable Vessels and in the Left Ventricle." In Cardiovascular Fluid Mechanics, 187–234. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-2542-7_4.

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Barsotti, Antonio, and Frank Lloyd Dini. "From Left Ventricular Dynamics to the Pathophysiology of the Failing Heart." In Cardiovascular Fluid Mechanics, 235–47. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-2542-7_5.

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Reneman, Robert S., Arnold P. G. Hoeks, and Lilian Kornet. "Element of Physiology and Mechanics of Human Arteries." In Cardiovascular Fluid Mechanics, 249–71. Vienna: Springer Vienna, 2003. http://dx.doi.org/10.1007/978-3-7091-2542-7_6.

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Hoskins, Peter R. "Introduction to Solid and Fluid Mechanics." In Cardiovascular Biomechanics, 1–24. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-46407-7_1.

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Pedrizzetti, Gianni. "Fluid Kinematics." In Fluid Mechanics for Cardiovascular Engineering, 39–51. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-85943-5_3.

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Pedrizzetti, Gianni. "Fluid Statics." In Fluid Mechanics for Cardiovascular Engineering, 21–37. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-85943-5_2.

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Conference papers on the topic "Cardiovascular fluid mechanic"

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Yap, Choon Hwai, Kerem Pekkan, and Ceilia Wen Ya Lo. "Using Episcopic Fluorescence Image Capture, Ultrasound Biomicroscopy and Computational Fluid Dynamics to Study Geometry and Fluid Mechanics of Mouse Fetus and Neonate." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80306.

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Khalili, Fardin, and Amirtahà Taebi. "Advances in Computational Fluid Dynamics Modeling of Cardiac Sounds as a Non-Invasive Diagnosis Method." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-73825.

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Abstract This paper provides a concise overview of the recent advances in the computational fluid dynamics modeling of flow-induced sounds, a valuable non-invasive tool that delivers complementary information for the early detection of cardiovascular and pulmonary diseases. An abnormal flow through an unhealthy artery consists of turbulent pressure fluctuations that interact with the arterial walls, leading to the sound waves propagated through the surrounding tissue. These sound waves recorded on the epidermal surface are vascular sounds known as murmurs. Detailed studies of the adverse flow conditions associated with cardiovascular and pulmonary diseases are vital to enhance our understanding of the mechano-acoustics mechanisms of flow-induced sound sources. This information can lead us to predictive, non-invasive techniques for diagnosing different diseases such as atherosclerosis and aneurysm before they progress to severe cases. This necessity suggests that more studies are necessary to develop strategies that can be employed to detect cardiovascular diseases without the need for invasive approaches.
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Smithee, Isaac, and Stephen P. Gent. "Computational Fluid Dynamics Modeling of Blood As a Heterogeneous Fluid." In 2018 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/dmd2018-6873.

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As the medical field continues to increase its effectiveness and scope, computational fluid dynamics (CFD) has become essential to understanding flow mechanics cardiovascular systems. Many simulations and experiments have been conducted to confirm the behavior of blood within veins and arteries, under both Newtonian and non-Newtonian conditions. Traditionally, these simulations have been conducted where blood is represented as a homogeneous fluid. However, blood is a heterogeneous fluid mixture, consisting of fluid plasma and solid components of red blood cells (RBC), white blood cells (WBC), and platelets. The effects of the heterogeneity of blood becomes more influential in blood flows through smaller diameter vessels and high velocity flows, as the addition of particles will create variations in flow speed, shear stress, and fluid displacement due to particle-particle and particle-wall collisions [1].
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Al-Rawi, M. A., A. M. Al-Jumaily, J. Lu, and A. Lowe. "A Fluid-Structure Interaction Model of Atherosclerosis at Abdominal Aorta." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-85912.

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Atherosclerosis is a form of cardiovascular disease that is a major contributing factor to death and disability worldwide. This study uses computational fluid dynamics (CFD) models as a cost effective and non-invasive method to determine the location and condition of atherosclerosis segments on the arterial wall. It also investigates changes in the abdominal aorta geometry including the inner and outer diameters, the length of the disease segments and the thickness of the arterial wall on the development of disease. Three groups of unhealthy conditions are assumed with each group having eight cases, which are compared to the control case of healthy condition. An invasive catheter pulsatile blood flow is imposed at the ascending aorta and pressure waveforms data is imposed at the four outlets of the aorta and also used to validate the present models. The results show that the stress phase angle at the brachial artery could be correlated to the early stages of atherosclerosis development at the abdominal aorta. This can be detected by measured values of the systolic wall shear stress and elastic strain intensity which increases due to the forward pulse wave resulting from atherosclerosis, while the diastolic values of stresses decreases due to the delay of the backward waves which reach the brachial artery. The three scenarios of atherosclerosis show that the forward and backward waves, which can be attributed to changes in the diameter, length and thickness of the abdominal aorta, can be non-invasively used to diagnose cardiovascular diseases.
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Hayasaka, Tomoaki, and Takami Yamaguchi. "INTEGRATED MODELING OF HUMAN CARDIOVASCULAR SYSTEM FOR THE CLINICAL APPLICATION OF COMPUTATIONAL FLUID MECHANICS." In Fourth International Symposium on Turbulence and Shear Flow Phenomena. Connecticut: Begellhouse, 2005. http://dx.doi.org/10.1615/tsfp4.1280.

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Al-Rawi, M. A., A. M. Al-Jumaily, and A. Lowe. "Computational Fluid Dynamics for Atherosclerosis and Aneurysm Diagnostics." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-37596.

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Non-invasive diagnosis of cardiovascular diseases is a valuable tool to reduce patient’s risk and discomfort. The main aim of this work is to investigate the possibilities of using computational fluid dynamics as a tool to investigate the biomechanical characteristics of the aorta under different medical conditions. These conditions include an aorta with healthy conditions, atherosclerosis and aneurysm. A three dimensional pulsatile flow model for an elastic aorta is developed and constructed in ANSYS® CFX 12. Abnormalities are simulated as diameter changes at the root of the ascending aorta. The computational model shows the reflection of these diseases on the blood flow and the artery wall at other locations downstream along the aorta. This 3D model has several advantages over previously published 1D and 2D models by giving more realistic results as compared with clinical trials.
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Kwon, Chi-Ho, Ki-Won Lee, and Young-Ho Kim. "Fluid-Structure Interactions Abdominal Aortic Aneurysm Models Under the Pulsatile Flow Condition." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2542.

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Abstract Fluid-structure interaction studies were performed on various abdominal aortic aneurysm (AAA) models under the pulsatile flow condition. Eight aneurysm models were made with four different dilatation sizes and two different wall thickness. Stresses and deformations of the aneurysm wall were significantly affected by the dilatation size as well as the wall thickness. The change in wall thickness increased with the more dilated aneurysm. In spite of considerable radial deformations, axial deformations of the aneurysm wall were dominant. The present study showed the strong possibility to understand fluid-structure interactions in the human cardiovascular system.
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Boutsianis, Evangelos, Thomas Frauenfelder, Hitendu Dave, Jurg Grunenfelder, Simon Wildermuth, Gregor Zund, Marko Turina, Dimos Poulikakos, and Yiannis Ventikos. "Cardiovascular Haemodynamic Simulations of Anatomically Accurate Coronaries." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-42728.

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The present study is devoted to the investigation of the pulsatile blood flow within the first few vessels of the Left Coronary Artery (LCA) vasculature of an anatomically accurate porcine coronary tree. Transient computational fluid dynamics simulations were performed under realistic pulsatile volume inflow boundary conditions. The numerical results have provided a comprehensive collection of information regarding the haemodynamics within the LCA and its major branches, namely the Left Anterior Descending (LAD) and the Left Circumflex (LCX) arteries. The underlying principle of developing computational techniques, which would eventually allow for the realistic simulation of the vascular haemodynamics of patients, lies on the capacity of such tools for predictive diagnostics and non-invasive, hence simulation-based, surgical planning.
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Jo-Avila, Miguel, Ahmed Al-Jumaily, and Jun Lu. "Predictive Cardiovascular Model With Blood Flow Measurements." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-51993.

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Cardiovascular disease is one of the leading causes of death in the world, accounting for 30% of all deaths worldwide and 40% of those occurring in New Zealand. In recent years, engineers and scientists have collaborated with the medical community to find new methodologies and approaches for assessing, investigating and understanding the development of cardiovascular diseases. Elements such as computational models developed with fluid dynamic elements (CFD/FE) have become excellent tools for this purpose. One of the important approaches is developing devices for investigating the central blood flow and pressure, and correlating the results to different heart diseases. Higher-valued changes in central blood flow and pressure mean that the heart must work harder. A computational model capable of predicting inlet and outlet locations of a blockage would be helpful to determine different stages of cardiovascular disease. By using reflection signals from the central blood flow that are detected at locations such as the brachial artery or subclavian artery, it is possible to model the effect of flow and pressure differences on heart diseases.
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Hewlin, Rodward L., and John P. Kizito. "Comparison of Carotid Bifurcation Hemodynamics in Patient-Specific Geometries at Rest and During Exercise." In ASME 2013 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/fedsm2013-16248.

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The ultimate goal of the present study is to determine whether investigations of flow patterns (flow reversal and flow branching) and mechanical factors (wall shear stress and normal stress) have a role in local risk factors and if flow modeling can truly rely on surrogate geometric sites (simplified geometries). Cardiovascular disease is considered to be the leading cause of morbidity and mortality across the world and improved methods of disease management are desperately needed. One of the main forms of cardiovascular disease is atherosclerosis. The presence of atherosclerotic plaques has been shown to be closely related to arterial vessel geometry and hemodynamic flow patterns. Computational fluid dynamic simulations were performed on 3 carotid bifurcation arteries to demonstrate that hemodynamic factors are significant determinants for the development of vascular pathology. Relationships between disturbed flow and various geometric factors from rest-state and exercise were examined. Wall shear stress, normal stress, and vorticity were used to verify the role of age, gender, and geometry on hemodynamic flow patterns.
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