Journal articles: 'Cardiovascular desease'

1

Maksic, Milanko, Lazar Davidovic, and Ivan Tomic. "Appearance of femoropopliteal segment aneurysms in patients with abdominal aortic aneurysm." Vojnosanitetski pregled 69, no. 9 (2012): 783–86. http://dx.doi.org/10.2298/vsp110314011m.

Full text

Abstract:

Background/Aim. To promote better treatment outcome, as well as economic benefit it is very important to find out patients with simultaneous occurrence of both aortic and arterial aneurysms. The aim of this prospective study was to determine the frequency and factors affecting femoropopliteal (F-P) segment aneurysms appearance in patients with abdominal aortic aneurysms (AAA). Methods. This study included 70 patients who had underwent elective or urgent surgery of AAA from January 1, 2006 to December 31, 2007. After ultrasonographic examination of F-P segment, all the patients were divided into two groups - those with adjunctive F-P segment aneurysm (n = 20) and the group of 50 patients with no adjunctive F-P segment aneurysm. In both groups demographic characteristics (gender, age), risk factors (diabetes mellitus, elevated serum levels of cholesterol and triglycerides, arterial hypertension, smoking, obesity) and cardiovascular comorbidity (cerebrovascular desease, ischemic heart desease) were investigated. Results. Twenty (28.57%) patients who had been operated on because of AAA, had adjunctive aneurysmal desease of F-P segment. Diabetes was no statistically significantly more present among the patients who, beside AAA, had adjunctive aneurismal desease of F-P segment (?2 = 0.04; DF = 1; p > 0.05). Also, in both groups there was no statistically significant difference in gender structure (?2 = 2. 05; DF = 2; p > 0.05), age (?2 = 5. 46; DF = 1; p > 0.05), total cholesterol level (?2 = 0.89; DF = 1; p > 0.05) and triglyceride (?2 = 0.89; DF = 1; p > 0.05) levels, the presence of arterial hypertension (?2 = 1.38; DF = 2; p > 0.05), smoking (?2 = 1.74; DF = 1; p > 0.05), obesity (?2 = 1.76; DF = 1; p > 0.05) and presence of cerebrovascular desease (?2 = 2.34; DF = 1; p > 0.05). Conversly, ischemic heart desease was statistically significantly more present among the patients who, beside AAA, had adjunctive aneurismal desease of F-P segment (?2 = 5.45; DF = 1; p < 0.05). Conclusion. Twenty patients, beside AAA, had adjunctive F-P segment aneurysm. The results of this study suggest the necessity of preforming ultrasonographic examination of F-P segment in all patients with proven AAA.

APA, Harvard, Vancouver, ISO, and other styles

2

Tashchuk, V., I. Makoviichuk, T. Kulyk, P. Ivanchuk, and L. Sidorchuk. "Lypanor and Zocor: Comparative effects under the ishemic heart desease." Atherosclerosis 144 (May 1999): 159–60. http://dx.doi.org/10.1016/s0021-9150(99)80614-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Poroshina, E. G., I. V. Vologdina, and E. V. Pestereva. "PSYCHOLOGICAL CHARACTERISTICS AND QUALITY OF LIFE OF CANCER PATIENTS WITH CONCOMITANT CARDIOVASCULAR PATHOLOGY." HERALD of North-Western State Medical University named after I.I. Mechnikov 9, no. 1 (March 15, 2017): 83–88. http://dx.doi.org/10.17816/mechnikov20179183-88.

Full text

Abstract:

The aim of the study was to explore the psychological characteristics and quality of life of patients with cancerous tumor combined with cardiovascular disease. 81 middle-aged patient (51,4±4,6 years) with cancer of different localization examined. Additionally, 42 patients had a concomitant cardiovas- cular pathology. Group of comparison consisted of 39 patients. The following tests and scales were used: test TOBOL for studying the issues of patients’ reaction to desease, Spielberger-Khanin scale to monitor level of anxiety, SF-36 questionnaire to analyze the quality of life. unlike the patients without cardiac pathology, the cancer patients with concomitant cardiovascular pathology showed higher anxi- ety and lower quality of life assessment

APA, Harvard, Vancouver, ISO, and other styles

4

Damjanovik, L., Z. Mitrev, and T. Ristova Dimova. "The importance of some life events to depresion of patients with cardio- surgery intervention (aorto-coronary bypass)." European Psychiatry 26, S2 (March 2011): 376. http://dx.doi.org/10.1016/s0924-9338(11)72085-5.

Full text

Abstract:

IntroductionThe cardiovascular desease is the great reason for mortality of the patiens. The comorbidity with the depression have a great influence of the incidence, morbidity and mortality. Some live events make the depression efects worse for the patient who take cardio-surgery treatment.Aimsis to find the importance of some life events to depression of the patients with cardio-surgery intervention.MethodsIn this study there was 30 patients, hospitalised at Cardiosugery Hospital Filip II, Skopje for cardio-surgery intervention (aorto-coronary by pass), 38–79 age, both male and female. These psychiatric instuments were used:Hamilton depression scale (HAMD), (17 itema scale with max score 52 and minimal score 0) and Scale for living stres factors of Holms and Rahe.ResultsThe average score of depression preoperation on HAMD scale is 16.77 ± 8.05, and the postoperation score were incresed to 21,25 and is high statistical significance (p < 0.01).The some events like death of member of the family, the illness, a big finansical changes significantly increace the depression (p < 0.01), but a newborn in the family, the holidays significantly decrese the depression on the participants (p < 0.05).ConclusionsMultidisciplinary approach with the team of psyciatrists, psychologist of patient with cardiovascular desease make the despression efects small and the patients have good recovery.

APA, Harvard, Vancouver, ISO, and other styles

5

Fischer, A., D. E. Gutstein, Z. A. Fayad, and V. Fuster. "Predicting plaque rupture: enhancing diagnosis and clinical decision-making in coronary artery desease." Vascular Medicine 5, no. 3 (August 1, 2000): 163–72. http://dx.doi.org/10.1191/135886300701568397.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Koppula, A., A. Parihar, A. Singh, V. Gupta, B. Parihar, M. Shinde, and B. Kutty. "CABG in left main desease with high risk euroscore-safe options." Indian Journal of Thoracic and Cardiovascular Surgery 22, no. 1 (March 2006): 66. http://dx.doi.org/10.1007/s12055-006-0615-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Kujiraoka, T., M. Ishihara, T. Fujioka, E. Saito, S. Saito, T. Egashira, and H. Hattori. "Measurement of paraoxonase (PON) concentrations in coronary heart desease (CHD) subjects by sandwich Elisa." Atherosclerosis 151, no. 1 (July 2000): 55. http://dx.doi.org/10.1016/s0021-9150(00)80248-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Hari, Rosida, and Dyan Maulani. "POTENSI INTERAKSI OBAT BISOPROLOL PADA PASIEN BPJS RAWAT JALAN DI POLI JANTUNG RUMAH SAKIT AL HUDA BANYUWANGI." JURNAL ILMIAH FARMASI AKADEMI FARMASI JEMBER 5, no. 2 (January 10, 2023): 64–71. http://dx.doi.org/10.53864/jifakfar.v5i2.117.

Full text

Abstract:

Cardiovascular desease become one of the main health problems in developed and developing countries. Cardiovascular patients generally occur in old age who have experienced decreased organ function and complications. They get prescriptions containing more than one type of drug so that spur the possibility of drug interactions. The most commonly prescribed cardiovascular drug is bisoprolol with combination. The study aimed to determinate of potential interactions of bisoprolol drugs in the prescription of outpatient patients at Al Huda Banyuwangi Hospital’s heart poly. This research was a descriptive study conducted retrospective on the BPJS recipe from January to March 2022. Data retrieval techniques were performed randomly which will then be studied theoretically based on literature. The results of 138 prescriptions taken random sampling included 125 prescriptions that had drug interactions. Of the 125 prescriptions there were 276 potential incidents of drug interactions with bisoprolol, based on the severity of major events of 13 (4.71%), moderate 253 (91.67%), and minor 10 (3.62%). The most interacting cardiovascular drug with bisoprolol was ISDN with an interaction of 47 events (17%) with the severity of moderate (strict monitors) that had an effect on increased hypotension effects, followed by aspirin as much as 37 events (13.4%) with the severity of moderate.

APA, Harvard, Vancouver, ISO, and other styles

9

Zanjanian, Mahsa, Meysam Mousaei, and Zahra Ghasemi. "Sociological Analysis of the Behavioral Style and Economic Status of Cardiovascular Desease Patientsin in Javad Al-Aemeh Heart Hospital of Mashhad." Social Welfare 22, no. 86 (November 13, 2022): 151–94. http://dx.doi.org/10.32598/refahj.22.86.3913.1.

Full text

Abstract:

Introduction: This is a sociological study of the economic burden on patients writh cardiovascular disease (CVD) based on the behavior change approach in their behavior in Javad Al-Aeme hospital of Mashhad in 2020. Method: This is a cross-sectional survey conducted on a population of 385 CVD patients of over 50 years of age admitted to the Training, Research and Treatment Center of Javad Al-Aeme hospital of Mashhad. Data were collected through a demographic profile form and a researcher-made questionnaire, the validity and reliability of which were measured using the content validity method and the Cronbach’s alpha method, respectively. SPSS and AMOS softwares and appropriate statistical tests were used for the data analysis purpose. Findings: The results of regression analysis demonstrated a significant positive relationship of the independent variables of the study, i.e. “socio-economic status”, “living conditions”, and “health-related capital” with patients’ behavioral style and economic status. The results of structural equation modeling (SEM) showed that the collected data confirm at an acceptable level the structural model with its extraneous variables, i.e. “socio-economic status”, “living conditions” and “health-related capital”. The total effects of these three variables on behavioral style were calculated to be 0.41. In other words, 41% of the behavioral style changes among cardiovascular patients can be explained by these three variables and 59% of the unexplained variance related to exogenous variables. It was also found that the effect of the behavior change approach on economic burden was -0.49%. Discussion: Since the behavioral style change, socio-economic status, health-related capital, and living conditions significantly affect the CVD, effective steps can be taken to prevent and control this disease and reduce its costs and economic burden by modifying and changing the patients’ behavioral style.

APA, Harvard, Vancouver, ISO, and other styles

10

Jakovtsova, I. I., I. I. Topchij, S. V. Daniluk, A. N. Kirienkow, and М. М. Dunaievska. "CHANGES OF MORPHOLOGY AND IMMUNOREACTIONS IN THE VESSELS OF KIDNEYS, HEART AND AORTA IN PATIENTS WITH CHRONIC KIDNEY DISEASE." Ukrainian Journal of Nephrology and Dialysis, no. 3(51) (August 29, 2016): 32–37. http://dx.doi.org/10.31450/ukrjnd.3(51).2016.04.

Full text

Abstract:

Chronic kidney diseases are etiology of complications in cardiovascular system. Structural and functional changes ofendothelium on a background ofimmunoreactions lies in basis ofthese disorders and complications. The aim of research was to study of morphologicalfeatures of kidneys and immune reactions in the vessels of kidneys, heart, aorta inpatients with CDK. Materials and methods. An autopsy material of the 20 dead’s age from 45 to 55 was investigated . The deceased had signs ofchronic desease of kidneys (CDK). Theprimary monoclonal antibody (PMA) company ofDAKO (Denmark) Rady - to - Use were used to reveal of features of cellular immunoreactions in the zones of inflammatoryprocess. We used microscope Primo Star (Carl Zeiss) with theprogram AxioCam (ERc 5s). Results and discussion. Changes of kidneys vessels, coronary arteries and aorta were characterized of transformation similar with immune inflammation. Condition of endothelium was characterized disorder of endothelization and manifest irregularity, lumpiness with outcrop of wide intercellular connections. All this proses bring to activation of apoptosis. Conclusion. Disturbance of vessel morphology and activity of immunoinflammatory reaction can be one of main cause ofdeveloping cardio-vascular complication.

APA, Harvard, Vancouver, ISO, and other styles

11

Metrikayanto, Wahyu Dini, Novita Dewi, and Rachmat Chusnul Choeron. "Riwayat Penyakit Kardiovaskuler Dan Kejadian Happy Hypoxia Pada Pasien Suspek Covid-19." Nursing News : Jurnal Ilmiah Keperawatan 5, no. 3 (September 24, 2021): 102–10. http://dx.doi.org/10.33366/nn.v5i3.2301.

Full text

Abstract:

ABSTRACT Happy Hypoxia is one of the symptoms of Covid-19 that is often not known by society. This condition is often found in cases of Covid-19 with very low oxygen levels in the blood. Happy Hypoxia can be fatal with the failure of several organs of the body. The purpose of this study was to determine the relationship between the incidences of happy hypoxia in suspected Covid-19 patients with a history of cardiovascular disease at the ER Panti Waluya Hospital, Malang. The design of this study was cross sectional with a total sample of 18 Covid-19 patients selected using the Total Sampling technique. Data about Happy Hypoxia and history of cardiovascular disease were taken based on secondary data from Medical Records in the ER Panti Waluya Hospital, Malang. Based on the results of the Fisher Exact Test, it was found that p = (0.0477) (0.050) so H1 was rejected, meaning that there was no relationship between the incidence of happy hypoxia in suspected Covid-19 patients with a history of cardiovascular disease in the ER Panti Waluyo Hospital, Malang City. This means that the incidence of happy hypoxia in Covid-19 patients is not only related to cardiovascular disease Keywords: cardiovascular desease, covid-19, happy hypoxia ABSTRAK Salah satu gejala Covid-19 yang sering tidak diketahui oleh masyarakat umum adalah happy hypoxia. Kondisi ini sering ditemukan kasus Covid-19 dengan kadar oksigen dalam darah sangat rendah sehingga bisa berdampak pada terjadinya pingsan atau bisa berakibat fatal juga dengan adanya kekagalan beberapa organ organ tubuh. Tujuan dari penelitian ini adalah untuk mengetahui Hubungan Kejadian Happy Hypoxia Pada Pasien Suspek Covid-19 Dengan Riwayat Penyakit Cardiovaskuler Di UGD Rs Panti Waluya Malang. Desain penelitian ini menggunakan cross sectional dengan jumlah sampel sebanyak 18 pasien Covid-19 yang dipilih dengan tekhnik Total Sampling. Data tentang Happy Hypoxia dan riwayat penyakit kardiovaskuler diambil berdasarkan data sekunder dari Rekam Medik di UGD RS Panti Waluya Malang. Berdasarkan hasil uji Fisher Exact Test didapatkan p = (0,477)(0,050) sehingga H1 ditolak, artinya tidak ada Hubungan Kejadian Happy Hypoxia Pada Pasien Suspek Covid-19 Dengan Riwayat Penyakit Kardivaskuler Di UGD RS Panti waluyo Kota Malang.. Hal ini memberikan makna bahwa kejadian happy hypoxia pada pasien Covid-19 tidak hanya berkaitan dengan penyakit kardiovaskuler. Kata kunci: Covid-19, Happy hypoxia, Penyakit Kardiovaskuler

APA, Harvard, Vancouver, ISO, and other styles

12

Husaini, Ahmad, Melda Yenni, and Cici Wuni. "efektivitas metode filtrasi dan adsorpsi dalam menurunkan kesadahan air sumur di kecamatan kota baru kota jambi." Jurnal Formil (Forum Ilmiah) Kesmas Respati 5, no. 2 (November 13, 2020): 91. http://dx.doi.org/10.35842/formil.v5i2.323.

Full text

Abstract:

Penggunaan air dengan kesadahan tinggi dan pH tidak netral dapat mengakibatkan kerusakan pada peralatan rumah tangga dan juga akan mengakibatkan gangguan kesehatan seperti cardiovascular desease dan urolithalisis. Air sumur yang digunakan masyarakat di wilayah kerja Kecamatan Kota Baru Kota Jambi memiliki kesadahan yang tinggi dengan ciri-ciri menimbulkan kerak pada peralatan masak, endapan warna putih pada tempat penampungan air.Penelitian ini bertujuan untuk mengetahui pengaruh metode filtrasi dan adsorpsi terhadap derajat pH air dan tingkat kesadahan air.Penelitian ini merupakan penelitian Quasi Eksperimen dengan rancangan time series design. Sampel penelitian ini yaitu air sumur. Pengambilan data dengan melakukan pengukuran pH menggunakan pH meter dan kesadahan air dengan metode titrimetri. Data di analisis dengan cara melihat perubahan derajat keasaman (pH) dan persentase perubahan kesadahan air.Hasil penelitian menunjukkan pH air sebelum pengolahan yaitu 4 dan meningkat pada lama kontak <1 menit menjadi 6,2, 6,5 pada lama kontak 30 menit, 6,3 pada lama kontak 60 menit, 6,2 pada lama kontak 90 menit dan 6,7 pada lama kontak 120 menit. Persentase penurunan kesadahan air pada waktu kontak <1 menit sebesar 7,14%, lama kontak 30 menit sebesar 15,35%, lama kontak 60 menit sebesar 36,42%, lama kontak 90 menit sebesar 38,57% dan lama kontak 120 menit sebesar 62,85%.Terdapat peningkatan derajat pH air sumur dan penurunan tingkat kesadahan air sumur setelah dilakukan pengolahan dengan cara filtrasi dan adsorpsi. Semakin lama kontak dalam proses filtrasi dan adsorpsi akan semakin efektif terhadap peningkatan pH air sumur dan penurunan tingkat kesadahan air sumur.

APA, Harvard, Vancouver, ISO, and other styles

13

Bazhenova, N. M. "DETERMINATION OF PLASMA HEMOSTASIS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE COMBINED WITH STAGE II HYPERTENSION BYUSING HIGHLY SPECIFIC SNAKE VENOMS." Ukrainian Scientific Medical Youth Journal, no. 3(102) (September 14, 2017): 5–9. http://dx.doi.org/10.32345/usmyj.3(102)().2017.5-9.

Full text

Abstract:

Most clotting factors are constantly formed by the liver and are constantly used in the body. Diseases of the liver, which violate the normal synthesis of these proteins, can lead to changes in the system of hemostasis. Among liver diseases, the most common is non-alcoholic fatty liver disease (NAFLD). NAFLD is an independent risk factor for the development and progression of cardiovascular diseases (CVD). The accumulated clinical experience of the study of hypertension (HT), as the most common disease among CVD, allows us to regard high blood pressure as one of the etiological factors of thrombogenic changes in the blood. The aim of the work was to determine the state of plasma hemostasis by using coagulation tests based on highly specific snake venoms in patients with NAFLD combined with stage II HT. In patients with NAFLD Echitoxic time is prolonged, indicating a slowing of clot formation at Factor II level of the clotting. For patients with NAFLD, as an independent desease, and in combination with stage II HT, it is characteristic to suppress the coagulation process along the external pathway of blood coagulation, which is indicated by the prolongation time of the Lebetox test. The combined NAFLD and HT accelerates the formation of thrombus in the last phase of clot formation, at the stage of converting the fibrinogen molecule to fibrin, which, against the background of an prolonged Lebetox test, indicates possible coagulopathy of consumption in the early stages of blood clotting to the formation of a prothrombin complex.

APA, Harvard, Vancouver, ISO, and other styles

14

El Joumani, T., T. Latifa, I. Hmamouchi, S. Ahid, R. Abouqal, L. Achemlal, I. El Bouchti, et al. "AB0246 COMORBIDITIES APPEARING UNDER BIOLOGIC THERAPY: PREVALENCE AND ASSOCIATED FACTORS." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 1148.2–1148. http://dx.doi.org/10.1136/annrheumdis-2021-eular.4280.

Full text

Abstract:

Objectives:The aims of our study are to determine the new comorbidities appearing under biologic therapy, their prevalence, and the factors implicated in their appearance.Methods:It’s a multicentric historical-prospective cohort including 10 rheumatology departments of Moroccan University Hospitals. The data were collected from the national register of patients under biologic therapy supervised by the Moroccan Society of Rheumatology. An electronic follow-up questionnaire is completed every 6 months by the investigator.Results:The study included 418 patients: 224 with Rheumatoid Arthritis (RA) who represented 53.6% and 194 with spondyloarthropathy (SP) who represented 46.4%.The prevalence rate of comorbidities appearing after one year of treatment with biologic therapy was 15.7% in RA and 8.4% in SP. The rate of cardiovascular diseases was 12.9% (arterial hypertension, myocardial infarction and/or ischemic stroke), 6.4% was the same value of hypercholesterolemia and depression, diabetes 3.3%, ulcer 3.2%, and osteoporosis 9.7%. The sedentary rate was 54.8% and smoking was about 3.3%.No patient had developed hypertriglyceridemia or chronic obstructive pulmonary disease.In the group of patients with RA, the average age of the patients who had developed a new comorbidity was 51,8 ± 11,3 years, women represented 87.5%, the average of Body Mass Index (BMI) was 27,6 ± 5,9 and the average duration of the disease was 14,1 ± 9,2 years. The disease activity score (DAS28) had an average of 3,15 ± 1,47.59.6% of patients used Rituximab, 23.8% Tociluzimab, 8.1% Etanercept, 5.8% Adalimumab, 0.18% Infliximab, and 0.9% Golimumab.In the group of patients with SP, the average age of the patients who had developed a new comobidity was 40,2 ± 13,7 years, men represented 63.4%, and the average of BMI was 24,3 ± 4,94.The activity of the desease, had an average Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) of 2,62 ± 1,79 and ankylosing Spondylitis Disease Activity Score (ASDAS) of 1,93 ± 1,09.Regarding the type of biologic therapy, 33.2% of patients used Etanercept, 30.1% Adalimumab, 24.9% Infliximab, 9.8% Golimumab, 1.6% Secukinumab, and 0.5% Tociluzimab.Conclusion:Our study showed a high prevalence of cardiovascular disease in patients under biologic therapy. This can be explained by the sedentary lifestyle secondary to rheumatic disease.Disclosure of Interests:None declared

APA, Harvard, Vancouver, ISO, and other styles

15

Wernly, Bernhard, and Zhichao Zhou (周稚超). "More purinergic receptors deserve attention as therapeutic targets for the treatment of cardiovascular disease." American Journal of Physiology-Heart and Circulatory Physiology 319, no. 4 (October 1, 2020): H723—H729. http://dx.doi.org/10.1152/ajpheart.00417.2020.

Full text

Abstract:

Cardiovascular disease is a major cause of morbidity and mortality worldwide. Innovative new treatment options for this cardiovascular pandemic are urgently needed. Activation of purinergic receptors (PRs) is critically involved in the development and progression of cardiovascular disease including atherosclerosis, ischemic heart disease, hypertension, and diabetes. PRs have been targeted for the treatment of several cardiovascular diseases in a clinical setting. The P2Y12R antagonists such as clopidogrel, ticagrelor, and others are the most successful class of purinergic drugs targeting platelets for the treatment of acute coronary syndrome. In addition to targeting platelets, ticagrelor may exert P2Y12R-independent effect by targeting erythrocyte-mediated purinergic activation. The partial A1R agonist neladenoson and the A2AR agonist regadenoson have been applied in cardiovascular medicine. In experimental studies, many other PRs have been shown to play a significant role in the development and progression of cardiovascular diseases, and targeting these receptors have resulted in promising outcomes. Therefore, many of these PRs including A2BR, A3R, P2X3R, P2X4R, P2X7R, P2Y1R, P2Y4R, P2Y6R, and P2Y11R can be considered as therapeutic targets. However, the multitude of PR subtypes expressed in different cells of the cardiovascular system may constitute a challenge whether single or multiple receptors should be targeted at the same time for the best efficacy. The present review discusses the promising purinergic drugs used in clinical studies for the treatment of cardiovascular disease. We also update experimental evidence for many other PRs that can be considered as therapeutic targets for future drug development.

APA, Harvard, Vancouver, ISO, and other styles

16

TOTH, M. "Elevated plasma levels and urinary excretion of ouabain like compound in cardiovascular deseases." American Journal of Hypertension 12, no. 4 (April 1999): 59. http://dx.doi.org/10.1016/s0895-7061(99)80194-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Ploshchenko, Y., and O. Klygunenko. "[PP.03.07] INFLUENCE OF ANAESTHESIA ON THE CYTOKINEʼS LEVEL IN ELDERLY WITH CONCOMITANT CARDIOVASCULAR DESEASES." Journal of Hypertension 35 (September 2017): e109. http://dx.doi.org/10.1097/01.hjh.0000523267.62818.f1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Ruilope, Luis M., Julian Segura, Toshiro Fujita, and Eberhard Ritz. "Renal and cardiovascular events: do they deserve the same consideration in clinical trials?" Journal of Hypertension 27, no. 9 (September 2009): 1743–45. http://dx.doi.org/10.1097/hjh.0b013e32832e0b19.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Klimova, A. A., L. G. Ambatello, E. V. Smolyakova, S. Yu Nistor, K. A. Zykov, and I. E. Chazova. "The problem of broncho-obstructive syndrome early detection in cardiological patients. Review of specialized respiratory questionnaires and their use in patients with comorbid cardiovascular and broncho-obstructive pathologies." Systemic Hypertension 15, no. 1 (March 15, 2018): 38–44. http://dx.doi.org/10.26442/2075-082x_15.1.38-44.

Full text

Abstract:

The management of patients with cardiovascular pathology and comorbid obstructive pulmonary diseases seems to be an urgent problem against the background of their widespread prevalence among the adult population. According to the latest recommendations of GOLD 2017, it is not possible to diagnose COPD and to select options for pharmacotherapy without assessing the symptoms. Evaluation of symptoms in patients with cardiorespiratory pathology is a key element in the diagnosis of both respiratory and cardiovascular deseases. It is important to conduct differential diagnosis of both nosologies for reliable evaluation of the results of standardized respiratory questionnaires. Many respiratory questionnaires have been developed now; some of them have been validated and recommended for use in clinical practice in patients with COPD and asthma. However, their sensitivity and specificity are different, these questionnaires can`t be used interchangeably. In some cases, a decrease in the informative value of standardized respiratory questionnaires was revealed in patients with comorbid cardiovascular and obstructive pulmonary diseases. There are extremely few scientific works, that assess the same aspects of this problem. In connection with this, the development of specialized questionnaires for patients with comorbid cardiovascular and obstructive pulmonary pathology is relevant.

APA, Harvard, Vancouver, ISO, and other styles

20

Jones, Erika L., and James C. Blankenship. "Women deserve the best care." Catheterization and Cardiovascular Interventions 100, no. 5 (November 2022): 936–37. http://dx.doi.org/10.1002/ccd.30434.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Kukar, Atul, and George D. Dangas. "Peripheral studies deserve center stage!" Catheterization and Cardiovascular Interventions 100, no. 5 (November 2022): 927–28. http://dx.doi.org/10.1002/ccd.30430.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Patel, Payal, and Lily Cheng. "The role of clopidogrel in the emergency department." CJEM 7, no. 01 (January 2005): 22–27. http://dx.doi.org/10.1017/s1481803500012896.

Full text

Abstract:

Despite major advances in the management of acute coronary syndromes (ACS), 1 in 3 Canadians die from cardiovascular disease. In 1998, the total economic burden of cardiovascular illness in Canada was $159 434.5 million dollars — $83 953.9 million in direct costs and $75 479.6 in indirect costs. During the past 20 years, several pharmacologic adjuncts have been investigated with hopes of ameliorating the consequences of ACS. Notably, clopidogrel has become a common component of ACS therapeutic regimens since its introduction in 1998. Both new medications and those already accepted as standard treatment deserve critical evaluation to ensure they are safe and effective.

APA, Harvard, Vancouver, ISO, and other styles

23

VALENTINUZZI, MAX E. "Horses Also Deserve Our Respect and Love." Pacing and Clinical Electrophysiology 28, no. 3 (February 25, 2005): 241–42. http://dx.doi.org/10.1111/j.1540-8159.2005.08152.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Alonso, Francisco, Cristina Esteban, Andrea Serge, and Macarena Tortosa. "Importance of Social- and Health-Related Problems: Do Spaniards Give Them the Significance They Actually Deserve?" International Journal of Environmental Research and Public Health 16, no. 21 (October 24, 2019): 4090. http://dx.doi.org/10.3390/ijerph16214090.

Full text

Abstract:

Social and health problems imply an impact on society. The main objective of this study is to provide an overview of how Spanish people perceive cancer, terrorism, cardiovascular diseases, crime, AIDS, drugs, and traffic accidents, finding out whether they assess the importance of these issues in correspondence with their actual severity. The study used a full sample of 1206 Spaniards (51.6% females and 48.4% males) who responded to a computer-assisted telephone interviewing (CATI) survey on the significance of these social and health-related problems, assessed through a zero to ten Likert scale. The perceived severity of the problems was considered taking into account the official data of deaths reported by governmental institutions. For the comparison of mean values, the One-way Analysis of Variance (ANOVA) test was used. Results show high average values for all the problems. The most concerning elements are cancer (M = 9.28 ± 1.24) and terrorism (M = 9.22 ± 1.47). Cardiovascular diseases have the lowest scores (M = 8.29 ± 1.64). There is a good adjustment between real and subjective perception, but some issues are either underestimated or overestimated. Women assessed all of them as more important than men, and people over 65 gave all the issues more value than younger people. It is important that Spaniards understand the objective severity of these issues, thus allowing for more interventions by governments, education, and mass media.

APA, Harvard, Vancouver, ISO, and other styles

25

Pozzi, Edoardo, Paolo Capogrosso, Luca Boeri, Federico Belladelli, Andrea Baudo, Nicolò Schifano, Costantino Abbate, Federico Dehò, Francesco Montorsi, and Andrea Salonia. "Longitudinal Risk of Developing Cardiovascular Diseases in Patients With Erectile Dysfunction—Which Patients Deserve More Attention?" Journal of Sexual Medicine 17, no. 8 (August 2020): 1489–94. http://dx.doi.org/10.1016/j.jsxm.2020.03.012.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Davidson, Beth Towery. "CHAMP-HF: Patients deserve more…" Heart & Lung 48, no. 1 (January 2019): 72. http://dx.doi.org/10.1016/j.hrtlng.2018.09.012.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Emelina, E. I., A. A. Ibragimova, P. A. Dreval, Gennady E. Gendlin, I. G. Nikitin, I. E. Byalik, and E. A. Antuch. "CONSEQUENCES OF RADIATION THERAPY OF ONCOLOGICAL DISEASES: FOCUS ON PERICARDITIS." Medical Journal of the Russian Federation 25, no. 2 (April 15, 2019): 120–26. http://dx.doi.org/10.18821/0869-2106-2019-25-2-120-126.

Full text

Abstract:

Radiation exposure of the chest is associated with a significant risk of subsequent development of cardiovascular diseases. Associated cardiovascular injuries include pericardial disease, coronary artery disease, valvular disease, conduction disease, cardiomyopathy, and vasculopathy. This article presents the development of different variants of pericardial radiation damage, methods of diagnosis and treatment of these complications. Radiation damage to the pericardium can manifest as acute pericarditis, effusion with tamponade or without cardiac tamponade, effusion-constrictive or classic constrictive pericarditis. Algorithms for the diagnosis and treatment of patients with radiation pericarditis in connection with a long asymptomatic course in a number of patients deserve special attention. Careful history taking and identifying prior radiotherapy is important in this category of patients. Untimely diagnosis and late treatment of these complications leads to a decrease in the quality of life of patients and increases the risk of cardiovascular mortality.

APA, Harvard, Vancouver, ISO, and other styles

28

Israfil, Israfil, and Maria Agustina Making. "Blood Glucose Level, Blood Pressure, and Medication Behavior are related to Cardiovascular Complication in Hypertension Patient at Sikumana Public Health Center." Unnes Journal of Public Health 9, no. 1 (January 31, 2020): 50–55. http://dx.doi.org/10.15294/ujph.v9i1.28051.

Full text

Abstract:

Hypertension tends to be incurable and can only be controlled, including to prevent cardiovascular complications. The purpose of this study was to look at the relationship of age, gender, blood glucose level, blood cholesterol level, blood pressure, and medication behavior (consumption of drugs and health control) with the incidence of cardiovascular complications in patients with hypertension at the Public Health Center in Sikumana-Kupang City. This study used a cross sectional design with a sample of 87 hypertension patients. Data analysis used Rank Spearman's Test (α = 0.01). There were 50 respondents who had cardiovascular complications in the form of non- hemorrhagic stroke complications (NHS), complications of coronary artery deseases (CAD), NHS and CAD complications, and complications of anggina pectoris. Analysis of Rank Spearman indicated age had p = 0.404 and r = 0.091, gender had p = 0.161 and r = -0,152, blood glucose level had p = 0.000 and r = -0.390, blood cholesterol level had p = 0.272 and r = -0.119, blood pressure had p = 0.000 and r = +0.417, drug consumption had p = 0.000 and r = +0.439, and health control had p = 0.000 and r = +0.490. It was concluded that there were significant relationships between blood glucose levels, blood pressure, and medication behavior (which consists of the consumption of hypertension drugs and health control) with the incidence of cardiovascular complications in patients with hypertension at the Sikumana Public Health Center in Kupang City.

APA, Harvard, Vancouver, ISO, and other styles

29

Filimonova, A. A., Ye M. Shurpo, S. N. Kotlyarov, and A. A. Bulgakov. "Acute Myocardial Damage in COVID-19: Types, Mechanisms of Development, Diagnosis Criteria, Prognosis." NAUKA MOLODYKH (ERUDITIO JUVENIUM) 10, no. 3 (September 30, 2022): 311–26. http://dx.doi.org/10.23888/hmj2022103311-326.

Full text

Abstract:

INTRODUCTION: The pandemic of a new coronavirus infection, COVID-19, has placeda heavy burden on the health care system. Nowadays, the clinical and epidemic features of the disease are the subject of debate and have not been adequately studied. Studies on the effect of coronavirus on the cardiovascular system deserve special attention. They are of significant interest because myocardial damage is the second most frequent cause of death in COVID-19. The damaging effect of the virus on the cardiovascular system is multifactorial and is realized both through the direct effect of the virus on its elements and indirectly. In the long term, COVID-19 patients with myocardial lesions retain an increased risk of cardiovascular events and require monitoring by a cardiologist. CONCLUSION: Development of preventive measures, improvement of diagnosis and treatment tactics of cardiovascular diseases in COVID-19 is the main task of further long-term studies. The present review aims to discuss the pathogenetic mechanisms of the development of the main forms of acute myocardial damage in COVID-19, as well as to analyze their clinical significance and approaches to diagnosis.

APA, Harvard, Vancouver, ISO, and other styles

30

Ferro, Charles J., and Jonathan N. Townend. "Risk for subsequent hypertension and cardiovascular disease after living kidney donation: is it clinically relevant?" Clinical Kidney Journal 15, no. 4 (December 13, 2021): 644–56. http://dx.doi.org/10.1093/ckj/sfab271.

Full text

Abstract:

ABSTRACT The first successful live donor kidney transplant was performed in 1954. Receiving a kidney transplant from a live kidney donor remains the best option for increasing both life expectancy and quality of life in patients with end-stage kidney disease. However, ever since 1954, there have been multiple questions raised on the ethics of live kidney donation in terms of negative impacts on donor life expectancy. Given the close relationship between reduced kidney function in patients with chronic kidney disease (CKD) and hypertension, cardiovascular disease and cardiovascular mortality, information on the impact of kidney donation on these is particularly relevant. In this article, we review the existing evidence, focusing on the more recent studies on the impact of kidney donation on all-cause mortality, cardiovascular mortality, cardiovascular disease and hypertension, as well as markers of cardiovascular damage including arterial stiffness and uraemic cardiomyopathy. We also discuss the similarities and differences between the pathological reduction in renal function that occurs in CKD, and the reduction in renal function that occurs because of a donor nephrectomy. Kidney donors perform an altruistic act that benefits individual patients as well as the wider society. They deserve to have high-quality evidence on which to make informed decisions.

APA, Harvard, Vancouver, ISO, and other styles

31

Vrsalovic, Mislav, and Victor Aboyans. "Antithrombotic Therapy in Lower Extremity Artery Disease." Current Vascular Pharmacology 18, no. 3 (April 24, 2020): 215–22. http://dx.doi.org/10.2174/1570161117666190206230516.

Full text

Abstract:

Lower extremity artery disease (LEAD) is a marker of a more advanced atherosclerotic process often affecting multiple vascular beds beyond the lower limbs, with a consequent increased risk for all-cause and cardiovascular mortality. Antithrombotic therapy is the cornerstone of management of these patients to prevent ischaemic cardiovascular and limb events and death. In patients with symptomatic LEAD, the efficacy of aspirin has been established long ago for the prevention of cardiovascular events. In the current guidelines, clopidogrel may be preferred over aspirin following its incremental ability to prevent cardiovascular events, while ticagrelor is not superior to clopidogrel in reducing cardiovascular outcomes. Dual antiplatelet therapy (DAPT, aspirin with clopidogrel) is currently recommended for at least 1 month after endovascular interventions irrespective of the stent type. Antiplatelet monotherapy is recommended after infra-inguinal bypass surgery, and DAPT may be considered in below-the-knee bypass with a prosthetic graft. In symptomatic LEAD, the addition of anticoagulant (vitamin K antagonists) to antiplatelet therapy increased the risk of major and life-threatening bleeding without benefit regarding cardiovascular outcomes. In a recent trial, low dose of direct oral anticoagulant rivaroxaban plus aspirin showed promising results, not only to reduce death and major cardiovascular events, but also major limb events including amputation. Yet, this option should be considered especially in very high risk patients, after considering also the bleeding risk. Despite all the evidence accumulated since >40 years, many patients with LEAD remain undertreated and deserve close attention and implementation of guidelines advocating the use of antithrombotic therapies, tailored according to their level of risk.

APA, Harvard, Vancouver, ISO, and other styles

32

Vilahur, Gemma. "Red Blood Cells Deserve Attention in Patients With Type 2 Diabetes." Journal of the American College of Cardiology 72, no. 7 (August 2018): 781–83. http://dx.doi.org/10.1016/j.jacc.2018.05.053.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Nilsson, Göran, John Öhrvik, Ingemar Lönnberg, and Pär Hedberg. "Ten-Year Survival in 75-Year-Old Men and Women: Predictive Ability of Total Cholesterol, HDL-C, and LDL-C." Current Gerontology and Geriatrics Research 2009 (2009): 1–7. http://dx.doi.org/10.1155/2009/158425.

Full text

Abstract:

Objective. The purpose of this study was to investigate prognostic impact of cholesterol and its subfractions among 75-year-old people from the general population.Methods and Results. The study comprised a random sample (222 women and 210 men) from the general population (participation rate 70%). During 10-year follow-up, 19% of women and 35% of men experienced a major cardiovascular event (MCVE). The all-cause mortality was 29% for women and 47% for men. After adjustment for cardiovascular risk factors, a low level of high-density lipoprotein cholesterol (HDL-C) was significantly associated with MCVE (P=.006) and mortality (P=.011) in men but not in women. The prognostic sex disparity was nearly significant (P=.051for MCVE and .067 for mortality). The associations of adjusted HDL-C to MCVE and mortality were unchanged after excluding individuals with prevalent stroke or MI. Total cholesterol and low-density lipoprotein cholesterol (LDL-C) were not significantly related to prognosis in either sex.Main Conclusions. HDL-C was associated with dismal prognosis in men but not in women. Elderly men with HDL-C <40 mg/dL deserve particular attention for cardiovascular prevention.

APA, Harvard, Vancouver, ISO, and other styles

34

Zelenikin, M. M., M. A. Zelenikin, S. S. Volkov, and D. K. Gushchin. "The surgical treatment of congenital heart deseases in young children in A.N. Bakoulev national medical research center for cardiovascular surgery in 2016 year." Bulletin of Bakoulev Center "Cardiovascular Diseases" 18, no. 6 (2017): 425–641. http://dx.doi.org/10.24022/1810-0694-2017-18-6-425-641.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Karadeniz, D., A. Mahmudova, and G. Benbir Senel. "0675 Periodic Leg Movements In Sleep Persisting After Treatment With Positive Airway Pressure Deserve Attention For Increased Cardiovascular Risk." Sleep 41, suppl_1 (April 2018): A250. http://dx.doi.org/10.1093/sleep/zsy061.674.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Capogrosso, P., E. Pozzi, E. Ventimiglia, W. Cazzaniga, L. Boeri, N. Schifano, F. Chierigo, et al. "PS-08-011 Longitudinal risk of developing cardiovascular diseases among patients with erectile dysfunction: Which patients deserve more attention?" Journal of Sexual Medicine 16, no. 5 (May 2019): S29. http://dx.doi.org/10.1016/j.jsxm.2019.03.115.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Basu, Arpita. "Role of Berry Bioactive Compounds on Lipids and Lipoproteins in Diabetes and Metabolic Syndrome." Nutrients 11, no. 9 (August 22, 2019): 1983. http://dx.doi.org/10.3390/nu11091983.

Full text

Abstract:

Blood lipids are an important biomarker of cardiovascular health and disease. Among the lipid biomarkers that have been widely used to monitor and predict cardiovascular diseases (CVD), elevated LDL and low HDL cholesterol (C), as well as elevated triglyceride-rich lipoproteins, deserve special attention in their predictive abilities, and thus have been the targets of several therapeutic and dietary approaches to improving lipid profiles. Among natural foods and nutraceuticals, dietary berries are a rich source of nutrients, fiber, and various types of phytochemicals. Berries as whole fruits, juices, and purified extracts have been shown to lower total and LDL-C, and increase HDL-C in clinical studies in participants with elevated blood lipids, type 2 diabetes or metabolic syndrome. This short review aimed to further discuss the mechanisms and magnitude of the lipid-lowering effects of dietary berries, with emphasis on reported clinical studies. Based on the emerging evidence, colorful berry fruits may thus be included in a healthy diet for the prevention and management of CVD.

APA, Harvard, Vancouver, ISO, and other styles

38

Zeman, Miroslav, Marek Vecka, František Perlík, Barbora Staňková, Robert Hromádka, Eva Tvrzická, Jakub Širc, Jakub Hrib, and Aleš Žák. "Pleiotropic effects of niacin: Current possibilities for its clinical use." Acta Pharmaceutica 66, no. 4 (December 1, 2016): 449–69. http://dx.doi.org/10.1515/acph-2016-0043.

Full text

Abstract:

Abstract Niacin was the first hypolipidemic drug to significantly reduce both major cardiovascular events and mortality in patients with cardiovascular disease. Niacin favorably influences all lipoprotein classes, including lipoprotein[a],and belongs to the most potent hypolipidemic drugs for increasing HDL-C. Moreover, niacin causes favorable changes to the qualitative composition of lipoprotein HDL. In addition to its pronounced hypolipidemic action, niacin exerts many other, non-hypolipidemic effects (e.g., antioxidative, anti-inflammatory, antithrombotic), which favorably influence the development and progression of atherosclerosis. These effects are dependent on activation of the specific receptor HCA2. Recent results published by the two large clinical studies, AIM-HIGH and HPS2-THRIVE, have led to the impugnation of niacin’s role in future clinical practice. However, due to several methodological flaws in the AIM-HIGH and HPS2-THRIVE studies, the pleiotropic effects of niacin now deserve thorough evaluation. This review summarizes the present and possible future use of niacin in clinical practice in light of its newly recognized pleiotropic effects.

APA, Harvard, Vancouver, ISO, and other styles

39

MATSUMORI, A. "P938 Early diagnosis of thrombosis by circulating hepatocyte growth factor in patients with unstable angina pectoris and other deseases." European Heart Journal 24, no. 5 (March 2003): 155. http://dx.doi.org/10.1016/s0195-668x(03)94230-8.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

De Obstetricia y Ginecologia, Federación Colombiana. "Conferencia de consenso sobre los anticonceptivos orales combinados y las enfermedades cardiovasculares." Revista Colombiana de Obstetricia y Ginecología 50, no. 4 (December 31, 1999): 229–34. http://dx.doi.org/10.18597/rcog.1010.

Full text

Abstract:

Desde la utilización en los años 60 de anticonceptivos combinados orales, muchos datos han sido recolectados por el mundo entero, y los anticonceptivos combinados por vía oral (ACO) representan hoy en día el grupo de agentes farmacológicos más investigado. En nuestros días, los ACO se utilizan por más de 90 millones de mujeres en el mundo entero y ofrecen a estas mujeres beneficios para la salud inadecuadamente apreciados. Las mujeres beneficían no sólo de la eficacia de los ACO para la prevención de un embarazo no deseado sino también de la prevención de anemia, de dismenorrea y de reglas abundantes (1), y de una disminución significante de algunos cánceres ginecológicos, o sea el cáncer del endometrio y él del ovario (2).

APA, Harvard, Vancouver, ISO, and other styles

41

Cavallari, Ilaria, and Giuseppe Patti. "Early risk of mortality, cardiovascular events, and bleeding in patients with newly diagnosed atrial fibrillation." European Heart Journal Supplements 22, Supplement_L (November 1, 2020): L110—L113. http://dx.doi.org/10.1093/eurheartj/suaa147.

Full text

Abstract:

Abstract Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is independently associated with a 1.5- to 2.0-fold higher risk of all-cause death and increased morbidity, in particular for heart failure and stroke. Previous studies have shown that the annual rate of death in AF patients is ∼5%; however, emerging data indicate that the risk of death, but also of thromboembolic and bleeding complications, is highest early after the diagnosis, especially during the first month. In light of these observations, patients with newly diagnosed AF deserve close monitoring and may benefit from a comprehensive care targeting modifiable risk factors for death, such as heart failure, diabetes, renal impairment, and vascular disease. Aim of this report is to focus on timing and causes of death as well as on temporal trends of cardiovascular and bleeding complications in patients with newly diagnosed AF.

APA, Harvard, Vancouver, ISO, and other styles

42

Klyachina, E. S., and O. G. Smolenskaya. "The risk of cardiac and cerebrovascular complications in patients with concomitant cardiovascular diseases who have had COVID-19." Clinical Medicine (Russian Journal) 99, no. 11-12 (March 4, 2022): 632–36. http://dx.doi.org/10.30629/0023-2149-2021-99-11-12-632-636.

Full text

Abstract:

During the pandemic caused by the SARS-CoV-2 virus, patients with cardiovascular diseases (CVD), which are often found in the population, are a special risk group. Cardiovascular complications after COVID-19 can occur at diff erent periods of the disease. This research describes cardiovascular complications in patients after recovery.The aim of the study was to identify the incidence of new CVD and complications of existing cardiac pathology in patients who recovered from COVID-19.Material and methods. A retrospective, observational study including 370 patients was conducted. All patients underwent telephone consultations within 6 months after the infectious diseases hospital discharge. When new CVDs, complications or anabasis were identifi ed, follow-up visits were initiated.Results. Among 370 patients under the study, concomitant CVD was registered in 249 (67.29%) people, 121 (32.71%) patients had no case history of cardiovascular pathology. In patients with concomitant CVD during the fi rst 6 months after the infectious diseases hospital discharge, 25 (10.04%) new cardiovascular events were registered, which is signifi cantly more frequent than in patients without case history of CVD (n = 1; 0.83%). The number of events described above was more often observed in the fi rst 3 months after discharge, which is statistically signifi cant (p ˂ 0.05). BP destabilization was most often observed (n = 67; 27.2%) as anabasis, which may be associated with an increased level of anxiety in patients. It was also noted that new CVDs, as well as anabasis, developed because of the timely specialized cardiological medical care absence, which probably led to undesirable events due to inability to correct CVD risk factors in time.Conclusions. In patients with concomitant CVD, who have had COVID-19, in contrast to patients without case history of CVD, the risk of developing new cardiovascular events is signifi cantly higher. Patients with CVD deserve the closest attention during the fi rst 3 months after discharge from the infectious diseases hospital.

APA, Harvard, Vancouver, ISO, and other styles

43

Rockwell, Helena, Eric J. Keller, Anthony Tadros, and Isabel Newton. "VIP Patients in Interventional Radiology: Do Some Patients Deserve “Better” Care?" Seminars in Interventional Radiology 39, no. 04 (August 2022): 454–58. http://dx.doi.org/10.1055/s-0042-1757316.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Hristova, Krasimira, Luidmila Vladimirova Kitova, Tzvetana Katova, Fedya Nikolov, Peter Nikolov, Sofia Georgieva, Iana Simova, and Velislava Kostova. "320 CORRELATION BETWEEN CAROTID ULTRASOUMD AND EXERCISE STRESS TEST FOR ASSESSING THE SUBLINICAL VASCULAR DESEASES IN HYPERTENSIVE PATIENTS." Journal of Hypertension 30 (September 2012): e93-e94. http://dx.doi.org/10.1097/01.hjh.0000420076.97413.79.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Prkacin, Ingrid, Petra Vrdoljak, Gordana Cavric, Damir Vazanic, Petra Pervan, and Visnja-Nesek Adam. "Resistant Hypertension and Cardiorenovascular Risk." BANTAO Journal 15, no. 1 (June 27, 2017): 6–9. http://dx.doi.org/10.1515/bj-2017-0002.

Full text

Abstract:

AbstractStudies have documented independent contribution of sympathetic activation to the cardiovascular disease continuum. Hypertension is one of the leading modifiable factors. Most if not all the benefit of antihypertensive treatment depends on blood pressure lowering, regardless how it is obtained. Resistant hypertension is defined as blood pressure that remains uncontrolled in spite of the concurrent use of three antihypertensive drugs of different classes. Ideally, one of the three drugs should be a diuretic, and all drugs should be prescribed at optimal dose amounts. Poor adherence to antihypertensive therapy, undiscovered secondary causes (e.g. obstructive sleep apnea, primary aldosteronism, renal artery stenosis), and lifestyle factors (e.g. obesity, excessive sodium intake, heavy alcohol intake, various drug interactions) are the most common causes of resistant hypertension. Cardio(reno)vascular morbidity and mortality are significantly higher in resistant hypertensive than in general hypertensive population, as such patients are typically presented with a long-standing history of poorly controlled hypertension. Early diagnosis and treatment is needed to avoid further end-organ damage to prevent cardiorenovascular remodeling. Treatment strategy includes lifestyle changes, adding a mineralocorticoid receptor antagonist, treatment adherence in cardiovascular prevention and, in case of failure to control blood pressure, renal sympathetic denervation or baroreceptor activation therapy. The comparative outcomes in resistant hypertension deserve better understanding. In this review, the most current approaches to resistant hypertension and cardiovascular risk based on the available literature evidence will be discussed.

APA, Harvard, Vancouver, ISO, and other styles

46

Engberding, Niels, and Nanette K. Wenger. "Acute Coronary Syndromes in the Elderly." F1000Research 6 (October 2, 2017): 1791. http://dx.doi.org/10.12688/f1000research.11064.1.

Full text

Abstract:

The clinical evidence for treatment of acute coronary syndrome (ACS) in the elderly is less robust than in patients younger than 75 years. The elderly have the highest incidence of cardiovascular disease and frequently present with ACS. This number can be expected to increase over time because society is aging. Older adults often sustain unfavorable outcomes from ACS because of atypical presentation and delay in recognition. In addition, elderly patients commonly do not receive optimal guideline-directed ACS treatment. Owing to their high baseline risk of ischemic complications, the elderly also fare worse even with optimal ACS treatment as they frequently have more complex coronary disease, more comorbidities, less cardiovascular reserve, and a higher risk of treatment complications. They are also subjected to a broader range of pharmacologic treatment. Treatment complications can be mitigated to some extent by meticulous dose adjustment of antithrombotic and adjunctive therapies. While careful transitions of care and appropriate utilization of post-discharge secondary preventive measures are important in ACS patients of all ages, the elderly are more vulnerable to system errors and thus deserve special attention from the clinician.

APA, Harvard, Vancouver, ISO, and other styles

47

Di Raimondo, Domenico, Gaia Musiari, Giuliana Rizzo, Edoardo Pirera, Alida Benfante, Salvatore Battaglia, Daniela Colomba, Antonino Tuttolomondo, Nicola Scichilone, and Antonio Pinto. "Echocardiographic Evaluation of the Cardiac Chambers in Asthmatic Patients: The BADA (Blood Pressure Levels, Clinical Features and Markers of Subclinical Cardiovascular Damage of Asthma Patients) Study-ECO." Journal of Personalized Medicine 12, no. 11 (November 5, 2022): 1847. http://dx.doi.org/10.3390/jpm12111847.

Full text

Abstract:

The “Blood pressure levels, clinical features and markers of subclinical cardiovascular Damage of Asthma patients” (BADA) study is aimed at defining the cardiovascular risk profile and the markers of subclinical and clinical vascular and cardiac damage in asthmatic patients. Very few studies have assessed asthmatic patients without concomitant heart disease through a transthoracic echocardiogram. The goal of the present study is to investigate the prevalence of morphology and/or function changes in the cardiac chambers of a sample of 86 patients with chronic asthma, referred to the dedicated outpatient unit of the Division of Respiratory Diseases of the AOUP “P. Giaccone” of the University of Palermo, and the results obtained were compared with those of a control group without respiratory or cardiovascular diseases. Patients with asthma showed a marked and widespread involvement of the four cardiac chambers compared with the controls: enlargement of the two atria, greater left ventricular remodeling with interventricular septal thickening, increased indexed left ventricular mass with a significantly greater percentage of patients with overt left ventricular hypertrophy, worse left ventricular diastolic function proven by the significant difference in the E/A ratio, and worse right ventricular systolic function with global right ventricular dysfunction estimated by the Myocardial Performance Index (Tei Index). Multivariate regression analysis, after adjustment for essential hypertension, hypertension severity, diabetes, Body Mass Index, and creatinine clearance, seems to indicate that the indexed left ventricular mass, right atrial volume, and right ventricular Tei index (but not left ventricular hypertrophy) correlate significantly with asthma, severe asthma, and FEV1 (and to a lesser extent with asthma duration). No correlation is apparent between inhaled therapy (ICS, SABA) and myocardial involvement. These results seem to confirm that a more in-depth cardiovascular evaluation in patients with chronic respiratory disease allows the identification of unrecognized cardiovascular involvement. A transthoracic echocardiogram performed in asthmatic patients without clinically overt signs or symptoms of cardiovascular impairment has identified some features indicative of an early subclinical cardiac impairment not found in the control group. These findings, considering also the higher frequency of hypertension in the asthma group, deserve further validation in the future.

APA, Harvard, Vancouver, ISO, and other styles

48

Mishra, Dheerendra Kumar, and Pradeep Kumar. "Electrocardiographic changes of antidepressant medication in depressive episode." International Journal of Advances in Medicine 5, no. 3 (May 22, 2018): 505. http://dx.doi.org/10.18203/2349-3933.ijam20181409.

Full text

Abstract:

Introduction: Depressive disorder is leading cause of mortality in the world, with the help of recent therapeutic strategies it is easily manageable. Antidepressant medication is the most commonly used for management of depressive disorders. Among the side effects of antidepressant, cardiovascular effects of antidepressant deserve close monitoring. Invariably, it is observed that patients undergoing antidepressant therapy are not screened for pre-existing cardiovascular diseases and more so for cardiotoxicity. Various antidepressant medications are available, with different cardiac side effects profile. Ignorance, over clinical burden, poor follow up and under evaluation of cardiovascular side effects could be attributable to an ultimate surveillance of such cases. So, this study conducted to evaluate electrocardiographic changes in therapeutic doses of antidepressant medication.Methods: An Open label-controlled study was conducted on 386 subjects to evaluate the antidepressant-induced electrocardiographic changes. Treatment seeking subjects for the depressive episode was recruited from outpatient and inpatient section of Psychiatry department after fulfilling inclusion and exclusion criteria. Data was collected on socio-demographic characteristics, and detailed pre-treatment and post-treatment clinical evaluation and electrocardiographic assessment were done.Results: Data collected and analyzed from 204 subjects, mean age of subjects taking tricyclics and SSRI (Fluoxitine) 43.6±7.5 years vs 41.5±9.6 years respectively. The study sample consists of 66% females, 33% males. Among them, 35% study subject expose to tricyclics and 65% subjects taking SSRI. 19% study subjects presented electrocardiograph changes especially tachycardia among them 55% was taking the tricyclic antidepressant. Only 10% subjects taking SSRI had post-treatment abnormal electrocardiograph changes.Conclusions: Conclusively, antidepressant form a safe therapeutic modality for the management of major depression. Its cardiovascular side effects warrant against indiscriminate use of particularly in high dose and old aged person and preexisting cardiac disease.

APA, Harvard, Vancouver, ISO, and other styles

49

Martel, E., P. Champeroux, P. Lacolley, S. Richard, M. Safar, and J. L. Cuche. "Central hypervolemia in the conscious rat: a model of cardiovascular deconditioning." Journal of Applied Physiology 80, no. 4 (April 1, 1996): 1390–96. http://dx.doi.org/10.1152/jappl.1996.80.4.1390.

Full text

Abstract:

The aim of the present study as to investigate whether increased central hypervolemia induced by tail suspension (TS) in the rat is an appropriate model of cardiovascular deconditioning (CVD). First, the physiological relationship between central venous pressure (CVP) and extracellular fluid volume (ECFV) was studied. TS (20 degrees) increased CVP (5.8 +/- 0.7 vs. 2.8 +/- 0.8 mmHg; P < 0.01). After 24 h of TS, CVP had returned to control range while ECFV was reduced by 19%. CVP kinetics during 24 h of TS was not affected by either reduction (-20%) or augmentation (/35%) of the ECFV. The normalization of CVP is likely to be a consequence of ECFV reduction, which itself is reduced by increased urinary excretion of water and sodium. Second, recovery from TS was studied. Resumption of the horizontal position was shown to be associated with a significant increase of heart rate (HR) and a slight reduction of blood pressure (BP); there was an apparent delay between increased HR and reduced BP. This imbalance between HR and BP is compatible with CVD. A model of simulated orthostatism (SO) was developed to further investigate the responses of HR and BP. Interestingly, SO (90 degrees rotation) in the normal rat was associated with significant tachycardia and a slight increase of BP. This pattern remained stable for at least 3 h. In rats that were tail suspended for 48 h, episodes of hypotension and bradycardia (5 +/- 1 in 3 h) suggested a defect in adaptation to increased hydrostatic pressure. In conclusion, TS appears to be an appropriate model of CVD. Reduction process. Return to horizontal position in TS rats induced a tachycardia with minimal effects on BP; this pattern is close to that observed in humans assuming upright posture. SO in previously TS rats disclosed episodes of hypotension and bradycardia that deserve further investigation.

APA, Harvard, Vancouver, ISO, and other styles

50

Mercy, James A., Clark W. Heath, and Mark L. Rosenberg. "Brief Research Report: Mortality Associated With the Use of Upper-Body Control Holds by Police." Violence and Victims 5, no. 3 (September 1, 1990): 215–22. http://dx.doi.org/10.1891/0886-6708.5.3.215.

Full text

Abstract:

A review of police records for the nine-year period from 1974 to 1982 identified 20 men who died following restraint by an upper-body control hold while in the custody of a large, urban police department. Using evidence from autopsy findings and police reports of events immediately preceding death, we concluded that control-hold use was associated with death in 19 of the 20 cases. This investigation points to three factors potentially associated with control hold-related death that deserve further investigation: Phencyclidine (PCP) use, sickle cell trait, and stress-related arrhythmias in the heart. PCP was detected in blood or other tissues from 6 of 17 decedents tested. Intravascular red blood cell sickling was found at autopsy in 4 of 14 black decedents (29%). Four decedents had some indication of cardiovascular abnormalities.

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'Cardiovascular desease'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles