Academic literature on the topic 'Cardiopulmonary bypass'

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Journal articles on the topic "Cardiopulmonary bypass"

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Cribben, Niall, Denise Gonoud, and Leo G. Kevin. "Cardiopulmonary bypass." Anaesthesia & Intensive Care Medicine 22, no. 4 (April 2021): 232–37. http://dx.doi.org/10.1016/j.mpaic.2021.02.006.

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Smith, D. "Cardiopulmonary Bypass." British Journal of Anaesthesia 104, no. 4 (April 2010): 513–14. http://dx.doi.org/10.1093/bja/aeq038.

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LAKE, CAROL L. "Cardiopulmonary Bypass." Anesthesiology 67, no. 3 (September 1987): 450. http://dx.doi.org/10.1097/00000542-198709000-00044.

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Ferraris, Victor A., Robert Klingman, Anthony Bufo, and Javid Saifi. "Cardiopulmonary bypass." Current Opinion in Cardiology 6, no. 2 (April 1991): 227–34. http://dx.doi.org/10.1097/00001573-199104000-00009.

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Murphy, Gavin J., and Alan J. Bryan. "Cardiopulmonary bypass." Surgery (Oxford) 22, no. 6 (June 2004): 126–28. http://dx.doi.org/10.1383/surg.22.6.126.38107.

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Grichnik, Katherine P. "Cardiopulmonary Bypass." Anesthesia & Analgesia 82, no. 5 (May 1996): 1114–15. http://dx.doi.org/10.1097/00000539-199605000-00066.

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Hensley, Frederick A. "Cardiopulmonary Bypass." Anesthesia & Analgesia 84, no. 2 (February 1997): 472. http://dx.doi.org/10.1097/00000539-199702000-00060.

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Roscoe, A. "Cardiopulmonary Bypass." Anaesthesia 66, no. 5 (February 24, 2011): 416. http://dx.doi.org/10.1111/j.1365-2044.2011.06679.x.

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Grichnik, Katherine P. "Cardiopulmonary Bypass." Anesthesia & Analgesia 82, no. 5 (May 1996): 1114–15. http://dx.doi.org/10.1213/00000539-199605000-00066.

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Hensley, Frederick A. "Cardiopulmonary Bypass." Anesthesia & Analgesia 84, no. 2 (February 1997): 472. http://dx.doi.org/10.1213/00000539-199702000-00060.

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Dissertations / Theses on the topic "Cardiopulmonary bypass"

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John, Alison Elizabeth. "Interleukin-8 and cardiopulmonary bypass." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301551.

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Linden, Matthew D. "The haemostatic defect of cardiopulmonary bypass." University of Western Australia. School of Surgery and Pathology, 2003. http://theses.library.uwa.edu.au/adt-WU2006.0009.

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[Truncated abstract] Cardiac surgery involving cardiopulmonary bypass is a complex procedure that results in significant changes to blood coagulation, fibrinolytic biochemistry, platelet number and function, and the vasculature. These are due to pharmacological agents which are administered, haemodilution and contact of the blood with artificial surfaces. Consequently there are significant risks of thrombosis and haemorrhage associated with this procedure. The research presented in this thesis utilises in vitro, in vivo, and a novel ex vivo model to investigate the nature of the haemostatic defect induced by cardiopulmonary bypass. The components studied include the drugs heparin, protamine sulphate, and aprotinin, different types of bypass circuitry (including heparin bonded circuits) and procedures such as acute normovolaemic haemodilution. Patient variables, such as Factor V Leiden, are also studied. Each of these components is assessed for the effects on a number of laboratory measures of haemostasis including activated partial thromboplastin time, prothrombin time, activated protein C ratio, antithrombin concentration, heparin concentration, thrombin-antithrombin complex formation, prothrombin fragment 1+2 formation, markers of platelet surface activation and secretion, activated clotting time, haemoglobin concentration and coagulation factor assays.
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Vassalos, Tony. "End organ effects of paediatric cardiopulmonary bypass." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/2385/.

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Despite the scientific, technological and surgical improvements of the past 50 years organ dysfunction following elective paediatric cardiac surgery utilising cardiopulmonary bypass continues to account for increased complications, often leading to a protracted course in hospital with a longer stay in intensive care and the potential for irreversible organ damage long term. Furthermore, paediatric cardiac surgeons are routinely undertaking more complex operations with a shift from palliation to early correction. This has resulted in younger children being subjected to longer periods on the bypass machine with increased effects on vital organs. This thesis describes two clinical studies designed to further assess and characterise peri-operative cardiac, renal and pulmonary function in children undergoing elective cardiac repair at a tertiary referral centre in Scotland, UK. In the first instance a prospective, observational study was undertaken in forty-five children to examine the use of tissue Doppler imaging in the assessment of peri-operative cardiac function, its relationship to myocardial injury and clinical outcome. Tissue Doppler parameters were obtained using a Vivid 7 ultrasound scanner with a 7-MHz probe pre-operatively, on admission to paediatric intensive care and on day one. Myocardial injury was assessed using Troponin-I on the first post-operative day by a commercially available chemiluminescent immunoassay. In twenty children within this group peri-operative renal function was also investigated using standard estimates of glomerular filtration rate, namely creatinine clearance measured by the kinetic Jaffe method during the first and second twelve hour post-operative periods, in comparison to serum creatinine and the novel biomarker cystatin C. Routine plasma retained pre-operatively and on days 0, 1, 2 and 3 post-operatively was used to measure serum cystatin C and creatinine using a particle-enhanced nephelometric immunoassay and the Roche Creatinine Plus enzymatic assay respectively. The association between cystatin C and recorded perfusion parameters including bypass duration, pump flow, haematocrit, oxygen delivery and Troponin-I was investigated. Peri-operative pulmonary function was evaluated through a phase IV, randomised, double-blind, placebo controlled trial. In total, twenty four children were randomised to receive oral sildenafil or equivalent volume placebo four times the day before surgery. Blood samples were collected peri-operatively to measure serum cyclic guanosine monophosphate with a commercially available competitive enzyme immunoassay. Haemodynamic data and echocardiography were acquired at two and twenty four hours post-operatively including pulmonary vascular resistance index and bi-ventricular contractility. Post-operative oxygenation was also determined at the same time by oxygen delivery and oxygenation index. In Chapter 2, peri-operative cardiac function as assessed by tissue Doppler imaging was examined. The results of this study demonstrated that pre-operatively, bi-ventricular systolic function in the study group was reduced compared with normal controls, displaying a significant step-wise decrease with increasing complexity of lesion. This picture persisted post-operatively predominantly in the right ventricle and was significantly associated with the extent of myocardial injury. Impaired peri-operative left ventricular function correlated with clinical outcomes. In Chapter 3, peri-operative renal function as assessed by cystatin C and its association with parameters of perfusion was examined. The results of this study demonstrated that in comparison to serum creatinine, cystatin C had a superior correlation with glomerular filtration rate in the early post-operative period. An elevated level of this biomarker was significantly associated with bypass duration, minimum pump flow and post-operative myocardial injury. Haematocrit was not directly linked to renal dysfunction in this study although evidence of a critical dysoxic threshold within the kidney was suggested indirectly through oxygen delivery calculations. In Chapter 4, peri-operative pulmonary function and vascular reactivity in association with the pre-operative administration of oral sildenafil (0.5mg/kg, six hourly) was examined. The results of this trial demonstrated that compared to placebo, pre-operative sildenafil resulted in modest elevations of serum cyclic guanosine monophosphate, limited effects on pulmonary vascular resistance index, significant reductions in peri-operative bi-ventricular contractility, significant reductions in post-operative oxygen delivery and a trend for increasing ventilatory support. In summary, the current thesis has demonstrated that in children undergoing corrective cardiac surgery peri-operative bi-ventricular function can be accurately assessed by tissue Doppler imaging which to date has had limited use in this patient group. With regards to renal function, cystatin C was shown to be a better estimate of glomerular filtration rate and a more sensitive marker of early renal dysfunction in children after surgery. Furthermore, cystatin C identified a transient post-operative renal impairment, the magnitude of which was associated with duration of bypass, pump flow and myocardial injury. In relation to pulmonary function, this research identified that pre-operative administration of oral sildenafil to children undergoing cardiac surgery produced limited effects on pulmonary vascular resistance but was associated with reduced ventricular contractility and post-operative oxygenation raising significant concerns over its routine clinical use.
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Baig, Kamran. "Effects of complement factor 1 inhibitor on cardiopulmonary function in neonatal cardiopulmonary bypass." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.497651.

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Svenmarker, Staffan. "Heparin coating and cardiotomy suction in cardiopulmonary bypass." Doctoral thesis, Umeå : Univ, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-134.

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Jones, J. M. "β2 adrenergic receptor gene therapy during cardiopulmonary bypass." Thesis, University of Cambridge, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.605686.

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Salameh, Aida, Stefan Dhein, Ingo Dähnert, and Norbert Klein. "Neuroprotective strategies during cardiac surgery with cardiopulmonary bypass." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-215752.

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Aortocoronary bypass or valve surgery usually require cardiac arrest using cardioplegic solutions. Although, in principle, in a number of cases beating heart surgery (so-called off-pump technique) is possible, aortic or valve surgery or correction of congenital heart diseases mostly require cardiopulmonary arrest. During this condition, the heart-lung machine also named cardiopulmonary bypass (CPB) has to take over the circulation. It is noteworthy that the invention of a machine bypassing the heart and lungs enabled complex cardiac operations, but possible negative effects of the CPB on other organs, especially the brain, cannot be neglected. Thus, neuroprotection during CPB is still a matter of great interest. In this review, we will describe the impact of CPB on the brain and focus on pharmacological and non-pharmacological strategies to protect the brain.
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Booker, Peter Driscoll. "Gut mucosal perfusion in infants undergoing hypothermic cardiopulmonary bypass." Thesis, University of Liverpool, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250543.

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Parratt, Rachel Nalini. "Monocyte activation of coagulation by cardiopulmonary bypass CPB circuits." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312851.

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Pallares, Luiz Carlos Marques. "Oxygen transport in cardiopulmonary bypass induced acute lung injury." Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307379.

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Books on the topic "Cardiopulmonary bypass"

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S, Ghosh, Falter Florian, and Cook, David J., M.D., eds. Cardiopulmonary bypass. Cambridge: Cambridge University Press, 2009.

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S, Ghosh, Falter Florian, and Cook, David J., M.D., eds. Cardiopulmonary bypass. Cambridge: Cambridge University Press, 2009.

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Ghosh, Sunit, Florian Falter, and Jr Perrino, eds. Cardiopulmonary Bypass. Cambridge: Cambridge University Press, 2015. http://dx.doi.org/10.1017/cbo9781139871778.

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Ghosh, Sunit, Florian Falter, and David J. Cook, eds. Cardiopulmonary Bypass. Cambridge: Cambridge University Press, 2009. http://dx.doi.org/10.1017/cbo9780511635564.

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Mora, Christina T., Robert A. Guyton, Donald C. Finlayson, and Richard L. Rigatti, eds. Cardiopulmonary Bypass. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6.

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1941-, Tinker John H., ed. Cardiopulmonary bypass: Current concepts and controversies. Philadelphia: Saunders, 1989.

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M, Taylor K., ed. Cardiopulmonary bypass: Principles and management. London: Chapman & Hall, 1986.

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A, Casthely Pierre, and Bregman David, eds. Cardiopulmonary bypass: Physiology, related complications, and pharmacology. Mount Kisco, NY: Futura Pub. Co., 1991.

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T, Mora Christina, ed. Cardiopulmonary bypass: Principles and techniques of extracorporeal circulation. New York: Springer-Verlag, 1995.

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A, Jonas Richard, and Elliott Martin J, eds. Cardiopulmonary bypass in neonates, infants and young children. Oxford: Butterworth-Heinemann, 1994.

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Book chapters on the topic "Cardiopulmonary bypass"

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Galletti, Pierre M., and Christina T. Mora. "Cardiopulmonary Bypass: The Historical Foundation, the Future Promise." In Cardiopulmonary Bypass, 3–18. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_1.

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Beckley, Philip D., David W. Holt, and Richard D. Tallman. "Oxygenators for Extracorporeal Circulation." In Cardiopulmonary Bypass, 199–219. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_10.

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Trocchio, Christopher R., and James O. Sketel. "Mechanical Pumps for Extracorporeal Circulation." In Cardiopulmonary Bypass, 220–28. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_11.

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Spitzer, Kathy K., and Charles T. Walker. "Conduits and Filters for Extracorporeal Circulation." In Cardiopulmonary Bypass, 229–37. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_12.

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Davis, Richard B., Jeffrey N. Kauffman, Terry L. Cobbs, and Sharon L. Mick. "Assembling and Monitoring the Extracorporeal Circuit." In Cardiopulmonary Bypass, 238–46. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_13.

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Rigatti, Richard L., and Roger Stewart. "Heat Exchange in Extracorporeal Systems." In Cardiopulmonary Bypass, 247–54. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_14.

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Connolly, Mark W. "Aortoatriocaval Cannulation for Cardiopulmonary Bypass." In Cardiopulmonary Bypass, 257–63. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_15.

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Zaidan, James R. "Initiation and Maintenance of Cardiopulmonary Bypass." In Cardiopulmonary Bypass, 264–80. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_16.

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Michelsen, Luis G., and Jack S. Shanewise. "Discontinuation of Cardiopulmonary Bypass." In Cardiopulmonary Bypass, 281–97. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_17.

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Sadel, Scott M. "Safety and Management of Perturbations During Cardiopulmonary Bypass." In Cardiopulmonary Bypass, 298–308. New York, NY: Springer New York, 1995. http://dx.doi.org/10.1007/978-1-4612-2484-6_18.

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Conference papers on the topic "Cardiopulmonary bypass"

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Sharkey, Claire, Alyssa Kimutis, Sadhna Ayesha Sharma, and Luke Starling. "896 Palivizumab post-cardiopulmonary bypass surgery." In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference–Online, 15 June 2021–17 June 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-rcpch.268.

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Heimeshoff, J., M. Ricklefs, W. Korte, C. Merz, F. Kirchhoff, A. Haverich, C. Bara, and C. Kühn. "Wearable Cardioverter Defibrillators after Cardiopulmonary Bypass Surgery." In 48th Annual Meeting German Society for Thoracic, Cardiac, and Vascular Surgery. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1678798.

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Rajaram, Ajay, Marianne Suwalski, Daniel Milej, Lawrence C. M. Yip, Linrui Ray Guo, Michael W. A. Chu, Jason Chui, Mamadou Diop, John Murkin, and Keith St. Lawrence. "Cerebral perfusion and metabolic neuromonitoring during cardiopulmonary bypass." In Optical Tomography and Spectroscopy of Tissue XIV, edited by Sergio Fantini and Paola Taroni. SPIE, 2021. http://dx.doi.org/10.1117/12.2578986.

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Rocha, E., R. Llorens, J. A. Paramo, R. Arcas, B. Cuesta, and A. Martin Trenor. "DOES DESMOPRESSIN ACETATE REDUCE BLOOD LOSS AFTER CARDIOPULMONARY BYPASS SURGERY?" In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644710.

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It has been suggested that desmopressin acetate (DDAVP) administration reduces blood loss after cardiac surgery. We have investigated the effect of DDAVP administration in a doubleblind, randomized, prospective trial including 60 patients undergoing cardiopulmonary bypass surgery. Thirty patients received 0.3 ug/kg DDAVP and 30 patients a placebo. The infusion was administered in a 50 ml saline solution over 15 min when cardiopulmonary bypass had been concluded. Blood samples were taken before surgery, immediately before and 90 min after DDAVP or placebo administration, and 24 hours postoperatively. The following parameters were measured in each sample: hematocrit, hemoglobin, platelet count, VIII:C and factor VIII:vWF. Bleeding time was also measured before operation and 90 min after treatment administration. Blood loss and transfusion requirements were evaluated from the beginning of treatment until 72 hours after surgery. Results showed no significant differences neither in total blood loss (833 ± 363 ml in the DDAVP group vs. 907 ± 646 in the placebo group) nor in blood transfusion (1633 ± 676 ml in the DDAVP group vs. 1643 ± 720 in the placebo group). The prolongation of bleeding time and the decrease of factor VIII:vWF, 90 min after treatment, were significantly lower (p < 0.05) in the DDAVP group as compared with the placebo group. We conclude that DDAVP administration does not reduce blood loss in patients undergoing cardiopulmonary bypass surgery, which would suggest a more complex mechanism to explain the increased bleeding in these patients.
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Burghard, A., M. Schakaki, J. Hillebrand, A. Hoffmeier, A. Imam, S. Martens, J. Roth, and J. Austermann. "The Effect of Cardiopulmonary Bypass on the Monocytes’ Tolerance." In 48th Annual Meeting German Society for Thoracic, Cardiac, and Vascular Surgery. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1678863.

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Robertson, Alex, and Richard Issitt. "108 Management of vein of galen on cardiopulmonary bypass." In GOSH Conference 2019, Care of the Complex Child. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2019. http://dx.doi.org/10.1136/archdischild-2019-gosh.108.

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Wiegand, G., C. Schlensak, M. Mustafi, W. Schneider, L. Sieverding, and M. Hofbeck. "Hybrid-implantation of a Pulmonary Valve Avoiding Cardiopulmonary Bypass." In 50th Annual Meeting of the German Society for Pediatric Cardiology (DGPK). Georg Thieme Verlag KG, 2018. http://dx.doi.org/10.1055/s-0038-1628335.

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Wilfart, Florentin M., Ainsley McFadgen, Blaine Kent, Kenneth Gardiner, and Michael K. Schmidt. "Delivery of Vapors on Cardiopulmonary Bypass using Different Oxygenator Membranes." In Biomedical Engineering. Calgary,AB,Canada: ACTAPRESS, 2011. http://dx.doi.org/10.2316/p.2011.723-091.

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Wachtfogel, Yanina T., Peter C. Harpel, L. Henry Edmunds, and Robert W. Colman. "FORMATION OF Cl -Cl INHIBITOR AND KALLIKREIN-Cl INHIBITOR COMPLEXES DURING CARDIOPULMONARY BYPASS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642900.

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Cardiopulmonary bypass prolongs bleeding time and increases postoperative blood loss. Contact of blood with synthetic surfaces during extracorporeal circulation leads to major qualitative and quantitative alterations in both platelets and neutrophils. Activation of platelets results in thrombocytopenia, decreased sensitivity of platelets to aggregating agents, decreased alpha2-adrenergic and fibrinogen receptors, secretion of thromboxane B2, and depletion of alpha-granule protein contents. Neutrophils,under similar conditions, have also been shown to release their specific granule protein, lactoferrin, and their azurophilic granule enzyme, elastase.We now investigate whether the classical complement, contact, or fibrinolytic pathways have been activated as potential sources of neutrophil agonists. Employing enzyme-linked immunosorbent “sandwich” assays specific for Cl -Cl inhibitor and kalli-krein-Cl inhibitor complexes respectively, we found that plasma levels of both of these formed complexes increased 2fold after clinical cardiopulmonary bypass was completed and reverted to baseline within 24 hours post-operatively. Since these complexes are cleared iji vivo, we investigated their plasma levels during jLn vitro simulated extracorporeal circulation. Over a period of 2 hours, Cl -Cl inhibitor complexes rose from a baseline of 2 + InM to 21 + 2 nM and kalli-krein-Cl inhibitor complexes rose from 2+1 nM to 25 + 5 nM. However, there was no evidence of either in vivo or vitro plasmin-alpha plasmin inhibitor complex formation. These results indicate that activation of the classical pathway of complement and the contact system in plasma may be associated with neutrophil activation seen during clinical cardiopulmonary bypass.
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Murin, P., W. Boettcher, S. Ozaki, A. Schulz, A. Wloch, Y. Cho, M. Redlin, O. Miera, N. Sinzobahamvya, and J. Photiadis. "Asanguineous Cardiopulmonary Bypass in Infants: Impact on Postoperative Mortality and Morbidity." In 51st Annual Meeting German Society for Pediatric Cardiology. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1679049.

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Reports on the topic "Cardiopulmonary bypass"

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Chai, Tianci, Zhihuang Qiu, Jian He, Hui Zheng, Fan Xu, Yunnan Hu, Hao Zhou, Yumei Li, and Liangwan Chen. Can high-dose corticosteroids in cardiopulmonary bypass bring more benefits?. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2020. http://dx.doi.org/10.37766/inplasy2020.6.0080.

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Khuri, S. F., C. R. Valeri, J. Loscalzo, M. Weinstein, and V. Birjiniuk. Heparin Causes Platelet Dysfunction and Induces Fibrinolysis Before the Institution of Cardiopulmonary Bypass. Fort Belvoir, VA: Defense Technical Information Center, September 1995. http://dx.doi.org/10.21236/ada360259.

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Khuri, Shukri F., Miguel Josa, Trevoc C. Axford, Samar Assousa, and Gina Ragno. Hematologic Changes During and Following Cardiopulmonary Bypass and Their Relationship to Non-Surgical Blood Loss. 1. Platelet Function and the Bleeding Time. Fort Belvoir, VA: Defense Technical Information Center, July 1990. http://dx.doi.org/10.21236/ada360145.

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Zhou, Youfa, Yanting Zhang, Jing Zhao, and Gang Chen. The effect of Nitric oxide delivered via cardiopulmonary bypass on postoperative outcomes in patients who underwent cardiac surgery: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2022. http://dx.doi.org/10.37766/inplasy2022.12.0002.

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QIN, Xiaoyu, Chunai WANG, Jie ZHANG, Shuwei WANG, and Weiqi ZHANG. Effectiveness and safety of electroacupuncture for myocardial protection in cardiopulmonary bypass patients with myocardial ischemia-reperfusion injury:a protocol for a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2021. http://dx.doi.org/10.37766/inplasy2021.4.0045.

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