Journal articles: 'Cardiac Functional Assessment'

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Waksmonski, Carol A. "Cardiac imaging and functional assessment in pregnancy." Seminars in Perinatology 38, no. 5 (August 2014): 240–44. http://dx.doi.org/10.1053/j.semperi.2014.04.012.

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Arnott, A. S. "Assessment of functional capacity in cardiac rehabilitation." Coronary Health Care 1, no. 1 (February 1997): 30–36. http://dx.doi.org/10.1016/s1362-3265(97)80037-5.

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Rubin, Daniel S. "Functional status assessment for preoperative cardiac risk prediction." International Anesthesiology Clinics 59, no. 1 (October 28, 2020): 15–21. http://dx.doi.org/10.1097/aia.0000000000000305.

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Pepin, Veronique, Wayne T. Phillips, and Pamela D. Swan. "Functional Fitness Assessment of Older Cardiac Rehabilitation Patients." Journal of Cardiopulmonary Rehabilitation 24, no. 1 (January 2004): 34–37. http://dx.doi.org/10.1097/00008483-200401000-00007.

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Redder, Elyse, Qiuhong Zhao, Naresh Bumma, Rami Kahwash, Ajay Vallakati, Courtney Campbell, Samir Parikh, et al. "Functional Impairments of Amyloidosis Patients: Physical Therapy Assessment." Hemato 3, no. 3 (June 23, 2022): 414–21. http://dx.doi.org/10.3390/hemato3030028.

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Amyloidosis is a rare, systemic disease that can result in significant functional impairment. Specific guidelines for the rehabilitation assessment of amyloidosis patients have yet to be established. The purpose of this study was to identify functional deficits and assess differences based on disease type, organ involvement, age, and gender of patients with amyloidosis. Materials and Methods: The multidisciplinary Comprehensive Amyloidosis Clinic (CAC) at Ohio State University (OSU) has developed structured assessment guidelines for amyloidosis patients. A retrospective, single-institution review of patients assessed in CAC between December 2017 and April 2020 was performed. Outcome measure data from the Timed Up and Go (TUG), 30 s sit-to-stand, and physical function portion of the SF 36 were gathered by chart review. Comparisons were made between CAC patient scores and normative data. Kruskal–Wallis tests were used to compare scores across the disease types (light chain, transthyretin wild-type, and hereditary variant transthyretin) and the Mann–Whitney U test was used for pairwise comparisons within disease types and cardiac involvement. Linear regression models were used to assess associations between patient characteristics (including age, gender, disease type, and cardiac involvement) and performance scores. Results: Data from sixty-four patients was evaluated. On the 30-s sit-to-stand test, patients with light chain amyloidosis performed 3.32 fewer repetitions than patients with transthyretin wild-type, p = 0.03. Patients with cardiac involvement had 2.55 fewer repetitions than patients without cardiac involvement, p = 0.03. Older patients were found to have slower TUG performance, and a 10-year increase in age was associated with an 11% increase in TUG scores. Conclusions: Findings indicate patients with light chain amyloidosis and patients with cardiac involvement, when compared to other amyloidosis patients, present with more physical impairments.

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Hameed, A., J. B. MacLeod, A. M. Yip, C. Aguiar, A. Adisesh, C. D. Brown, R. Forgie, and A. Hassan. "ASSESSMENT OF FUNCTIONAL RECOVERY IN PATIENTS FOLLOWING CARDIAC SURGERY." Canadian Journal of Cardiology 32, no. 10 (October 2016): S114—S115. http://dx.doi.org/10.1016/j.cjca.2016.07.168.

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Coyne, Karin S., and Jerilyn K. Allen. "Assessment of functional status in patients with cardiac disease." Heart & Lung 27, no. 4 (July 1998): 263–73. http://dx.doi.org/10.1016/s0147-9563(98)90038-3.

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Kolbitsch, Christoph, Claudia Prieto, and Tobias Schaeffter. "Cardiac functional assessment without electrocardiogram using physiological self‐navigation." Magnetic Resonance in Medicine 71, no. 3 (April 8, 2013): 942–54. http://dx.doi.org/10.1002/mrm.24735.

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Manabe, Osamu, Noriko Oyama-Manabe, and Nagara Tamaki. "Positron emission tomography/MRI for cardiac diseases assessment." British Journal of Radiology 93, no. 1113 (September 1, 2020): 20190836. http://dx.doi.org/10.1259/bjr.20190836.

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Functional imaging tools have emerged in the last few decades and are increasingly used to assess the function of the human heart in vivo. Positron emission tomography (PET) is used to evaluate myocardial metabolism and blood flow. Magnetic resonance imaging (MRI) is an essential tool for morphological and functional evaluation of the heart. In cardiology, PET is successfully combined with CT for hybrid cardiac imaging. The effective integration of two imaging modalities allows simultaneous data acquisition combining functional, structural and molecular imaging. After PET/CT has been successfully accepted for clinical practices, hybrid PET/MRI is launched. This review elaborates the current evidence of PET/MRI in cardiovascular imaging and its expected clinical applications for a comprehensive assessment of cardiovascular diseases while highlighting the advantages and limitations of this hybrid imaging approach.

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Veitla, Vineet, and Bhavna Bhasin. "Focused Cardiac Assessment in Kidney Care." POCUS Journal 7, Kidney (February 1, 2022): 45–50. http://dx.doi.org/10.24908/pocus.v7ikidney.14996.

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Point of care ultrasonography (POCUS) is considered to be a very useful and informative extension of the bedside physical exam. The information obtained from POCUS allows for real time assessment for expedited decision making to improve efficiency in patient care and management. Many programs across the country are now incorporating POCUS into their training schedules to allow their residents, fellows, and faculty to gain competence in the techniques and varied clinical uses of POCUS [1-3]. In nephrology, POCUS has been used at the bedside for access planning, dialysis catheter placement, and to guide kidney biopsies to mention a few applications [4]. There is a wide scope for POCUS in nephrology in addition to kidney and bladder assessment. This includes focused cardiac ultrasound to evaluate the heart for structural and functional abnormalities and lung ultrasound as well. These bedside ultrasound assessments help with point of care management decisions pertaining to volume assessment in acute and chronic kidney disease, adjustment of ultrafiltration goals in dialysis patients, and evaluation of hypotension and dyspnea.

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Yadav, Taruna, and Rengarajan Rajagopal. "Functional Assessment with Fetal Cardiac MRI in Congenital Diaphragmatic Hernia." Radiology 302, no. 2 (January 2022): 275. http://dx.doi.org/10.1148/radiol.2021211703.

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Menendez-Montes, Ivan, Maria Villalba-Orero, Beatriz Escobar, and Silvia Martin-Puig. "Embryonic echocardiography for assessment of congenital and functional cardiac defects." STAR Protocols 2, no. 4 (December 2021): 100980. http://dx.doi.org/10.1016/j.xpro.2021.100980.

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Tsuritani, Mitsuhiro, Yoshiaki Morita, Takekazu Miyoshi, Kenichi Kurosaki, and Jun Yoshimatsu. "Fetal Cardiac Functional Assessment by Fetal Heart Magnetic Resonance Imaging." Journal of Computer Assisted Tomography 43, no. 1 (2019): 104–8. http://dx.doi.org/10.1097/rct.0000000000000781.

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Toner, I. "Cerebral functional changes following cardiac surgery: Neuropsychological and EEG assessment." European Journal of Cardio-Thoracic Surgery 13, no. 1 (January 1998): 13–20. http://dx.doi.org/10.1016/s1010-7940(97)00300-x.

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Treibel, T. A., A. Rossi, F. Pugliese, and L. C. Davies. "Functional assessment of coronary artery disease by cardiac computed tomography." Expert Review of Cardiovascular Therapy 15, no. 9 (July 25, 2017): 657–65. http://dx.doi.org/10.1080/14779072.2017.1359087.

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Bhatia, Mona, and Parveen Kumar. "Cardiac MRI in this Era." Indian Journal of Cardiovascular Disease in Women - WINCARS 5, no. 04 (December 2020): 335–42. http://dx.doi.org/10.1055/s-0040-1722383.

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Abstract Cardiac MRI (CMR) in this era is fast emerging as an invaluable tool in assessment of a large gamut of cardiac pathologies to not only ascertain the diagnosis but also assess severity, enable prognostication of disease process, guide management, and follow-up patients. CMR is today the gold standard for accurate and reproducible cardiac functional assessment, with excellent soft-tissue contrast, and ability to evaluate myocardial involvement even without contrast objectively via mapping techniques. CMR is thus fast emerging as the modality of choice and exponentially growing for cardiac assessment.

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Kedev, Sasko, and Ivan Vasilev. "Assessment of Coronary Microcirculation During Cardiac Catheterization." Current Pharmaceutical Design 24, no. 25 (November 8, 2018): 2950–53. http://dx.doi.org/10.2174/1381612824666180702112018.

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Functional tests used in the catheterization laboratory have emerged as a very important adjunctive tool to coronary angiography that can identify patients with myocardial blood flow impairment. Fractional Flow Reserve (FFR) measurement is highly recommended for detection of ischemia-related coronary lesion(s) when objective evidence of vessel-related ischemia is not available. Recently, the much simpler instantaneous wave free ratio (iFR) was proposed as an alternative to FFR without the requirement for administration of vasodilators. More user-friendly techniques like iFR might further contribute to value-based care in coronary interventions.

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DeGuire, Steven, Richard Gevirtz, Yoshito Kawahara, and William Maguire. "Hyperventilation syndrome and the assessment of treatment for functional cardiac symptoms." American Journal of Cardiology 70, no. 6 (September 1992): 673–77. http://dx.doi.org/10.1016/0002-9149(92)90211-g.

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Xu, Lei, Zhonghua Sun, and Zhanming Fan. "Noninvasive Physiologic Assessment of Coronary Stenoses Using Cardiac CT." BioMed Research International 2015 (2015): 1–12. http://dx.doi.org/10.1155/2015/435737.

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Coronary CT angiography (CCTA) has become an important noninvasive imaging modality in the diagnosis of coronary artery disease (CAD). CCTA enables accurate evaluation of coronary artery stenosis. However, CCTA provides limited information on the physiological significance of stenotic lesions. A noninvasive “one-stop-shop” diagnostic test that can provide both anatomical significance and functional significance of stenotic lesions would be beneficial in the diagnosis and management of CAD. Recently, with the introduction of novel techniques, such as myocardial CT perfusion, CT-derived fractional flow reserve (FFRCT), and transluminal attenuation gradient (TAG), CCTA has emerged as a noninvasive method for the assessment of both anatomy of coronary lesions and its physiological consequences during a single study. This review provides an overview of the current status of new CT techniques for the physiologic assessments of CAD.

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Bratis, Konstantinos. "Cardiac Magnetic Resonance in Takotsubo Syndrome." European Cardiology Review 12, no. 1 (2017): 58. http://dx.doi.org/10.15420/ecr.2017:7:2.

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Takotsubo syndrome is an acute, profound but reversible heart failure syndrome of unknown aetiology, usually but not always triggered by physical or emotional stress. Cardiac magnetic resonance has become an important tool for the non-invasive assessment of the syndrome, allowing for a comprehensive, safe and reproducible assessment of functional and anatomical myocardial properties, including perfusion, oedema and necrosis. This review focuses on the emerging role of cardiac magnetic resonance for the characterisation, differential diagnosis as well as risk stratification of patients with Takotsubo syndrome.

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van den Bos, Ewout J., Richard B. Thompson, Anja Wagner, Heiko Mahrholdt, Yoshihisa Morimoto, Louise E. J. Thomson, Lynn H. Wang, Dirk J. Duncker, Robert M. Judd, and Doris A. Taylor. "Functional assessment of myoblast transplantation for cardiac repair with magnetic resonance imaging." European Journal of Heart Failure 7, no. 4 (May 28, 2005): 435–43. http://dx.doi.org/10.1016/j.ejheart.2003.12.022.

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Inozemtseva, Ye S., N. I. Goudomarova, and A. V. Kabachkova. "Cardiointervalographical assessment of the vegetovascular balance in girls engaged in fitness aerobics." Bulletin of Siberian Medicine 5, no. 4 (December 30, 2006): 71–73. http://dx.doi.org/10.20538/1682-0363-2006-4-71-73.

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Computer-aided systems for analysis of the cardiac rhythm allow the objective assessment of the functional state and peculiarities of the vegetative provision of functional reserves in an organism, revealing of the states of fatigue and overtraining, objective prediction and correction of the functional readiness to competition, development of the most favorable regime of training and recovery after physical activity.

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Guenther, Ulf, Falk Hoffmann, Oliver Dewald, Ramy Malek, Kathrin Brimmers, Nils Theuerkauf, Christian Putensen, and Julius Popp. "Preoperative Cognitive Impairment and Postoperative Delirium Predict Decline in Activities of Daily Living after Cardiac Surgery—A Prospective, Observational Cohort Study." Geriatrics 5, no. 4 (October 3, 2020): 69. http://dx.doi.org/10.3390/geriatrics5040069.

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Cardiac surgery and subsequent treatment in the intensive care unit (ICU) has been shown to be associated with functional decline, especially in elderly patients. Due to the different assessment tools and assessment periods, it remains yet unclear what parameters determine unfavorable outcomes. This study sought to identify risk factors during the entire perioperative period and focused on the decline in activity of daily living (ADL) half a year after cardiac surgery. Follow-ups of 125 patients were available. It was found that in the majority of patients (60%), the mean ADL declined by 4.9 points (95% CI, −6.4 to −3.5; p < 0.000). In the “No decline” -group, the ADL rose by 3.3 points (2.0 to 4.6; p < 0.001). A multiple regression analysis revealed that preoperative cognitive impairment (MMSE ≤ 26; Exp(B) 2.862 (95%CI, 1.192–6.872); p = 0.019) and duration of postoperative delirium ≥ 2 days (Exp(B) 3.534 (1.094–11.411); p = 0.035) was independently associated with ADL decline half a year after the operation and ICU. Of note, preoperative ADL per se was neither associated with baseline cognitive function nor a risk factor for functional decline. We conclude that the preoperative assessment of cognitive function, rather than functional assessments, should be part of risk stratification when planning complex cardiosurgical procedures.

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Troisi, Nicola, Raffaele Pulli, Walter Dorigo, Patrizia Lo Sapio, and Carlo Pratesi. "Preoperative cardiac assessment in patients undergoing major vascular surgery." Vascular 19, no. 4 (July 8, 2011): 178–86. http://dx.doi.org/10.1258/vasc.2010.oa0264.

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The aim of this study was to evaluate the effectiveness of a preoperative standardized cardiac assessment in patients undergoing major vascular surgery. From January 2005 to December 2006, 1446 elective interventions for major vascular diseases (carotid stenosis, CS; abdominal aortic aneurysm, AAA; peripheral arterial obstructive disease, PAOD) were performed; 1090 out of these patients underwent preoperative diagnostic assessment on an outpatient basis. Thirty-day results in terms of cardiac mortality and morbidity rates were recorded. Patients suffered from a CS in 578 cases (53%), an AAA in 303 cases (27.8%) and a PAOD in 209 cases (19.2%). Four hundred thirty-two patients (39.6%) underwent further evaluation of cardiac functional capacity with non-invasive stress testing. Sixteen patients were successfully treated prior to vascular surgery. Thirty-day cardiac mortality and morbidity rates were 0.2% and 3.9%, respectively. A positive preoperative non-invasive stress testing did not affect 30-day cardiac outcomes. In conclusion, the use of an accurate preoperative cardiac assessment allowed us to obtain satisfactory perioperative results in patients undergoing major vascular surgery. Routine preoperative evaluation with non-invasive stress testing did not seem to improve perioperative cardiac results.

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Teragawa, Hiroki, Chikage Oshita, and Yuichi Orita. "Is Noncardiac Chest Pain Truly Noncardiac?" Clinical Medicine Insights: Cardiology 14 (January 2020): 117954682091890. http://dx.doi.org/10.1177/1179546820918903.

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Many causes of noncardiac chest pain (NCCP) have been studied and gastroesophageal reflux disease is considered to be the major cause. However, studies have reported that treatment with a proton pump inhibitor does not effectively provide relief for NCCP-related symptoms, and these symptoms frequently recur. These findings suggest that patients with cardiac disease may be excluded completely from the NCCP group. Several examinations can be conducted to verify the presence of cardiac disease. Such examinations include the assessment of biochemical markers, rest and exercise electrocardiogram, echocardiography, cardiac computed tomography, stress myocardial perfusion imaging, cardiac magnetic resonance imaging, and coronary angiography (CAG). However, the presence of functional coronary artery diseases (CADs), such as vasospastic angina and/or microvascular angina, cannot be detected using these modalities. These functional CADs can be diagnosed by CAG with spasm-provocation testing and/or physiological coronary measurement. Thus, when a patient who is suspected of having NCCP takes a proton pump inhibitor and does not respond well, further examination—including assessment for possible functional CADs—may be needed.

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Badea, Cristian T., Elizabeth Bucholz, Laurence W. Hedlund, Howard A. Rockman, and G. Allan Johnson. "Imaging Methods for Morphological and Functional Phenotyping of the Rodent Heart." Toxicologic Pathology 34, no. 1 (January 2006): 111–17. http://dx.doi.org/10.1080/01926230500404126.

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Small animal imaging has a critical role in phenotyping, drug discovery, and in providing a basic understanding of mechanisms of disease. Translating imaging methods from humans to small animals is not an easy task. The purpose of this work is to compare two cardiac imaging modalities, i.e., magnetic resonance microscopy (MRM) and microcomputed tomography (CT) for preclinical studies on rodents. We present the two technologies, the parameters that they can measure, the types of alterations that they can detect, and show how these imaging methods compare to techniques available in clinical medicine. While this paper does not refer per se to the cardiac risk assessment for drug or chemical development, we hope that the information will effectively address how MRM and micro-CT might be exploited to measure biomarkers critical for safety assessment.

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Nakayama, Akira, Federica del Monte, Roger J. Hajjar, and John V. Frangioni. "Functional Near-Infrared Fluorescence Imaging for Cardiac Surgery and Targeted Gene Therapy." Molecular Imaging 1, no. 4 (October 1, 2002): 153535002002213. http://dx.doi.org/10.1162/15353500200221333.

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Cardiac revascularization is presently performed without realtime visual assessment of myocardial blood flow or perfusion. Moreover, gene therapy of the heart cannot, at present, be directed to specific territories at risk for myocardial infarction. We have developed a surgical imaging system that exploits the low autofluorescence, deep tissue penetration, low tissue scatter, and invisibility of near-infrared (NIR) fluorescent light. By completely isolating visible and NIR light paths, one is able to visualize, simultaneously, the anatomy and/or function of the heart, or any desired tissue. In rat model systems, we demonstrate that the heptamethine indocyanine-type NIR fluorophores IR-786 and the carboxylic acid form of IRDye78 can be injected intravenously in the living animal to provide real-time visual assessment of myocardial blood flow or perfusion intraoperatively. This imaging system may prove useful for the refinement of revascularization techniques, and for the administration of cardiac gene therapy.

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Cai, Shining, Jos M. Latour, Ying Lin, Wenyan Pan, Jili Zheng, Yan Xue, Jian Gao, et al. "Preoperative cardiac function parameters as valuable predictors for nurses to recognise delirium after cardiac surgery: A prospective cohort study." European Journal of Cardiovascular Nursing 19, no. 4 (November 1, 2019): 310–19. http://dx.doi.org/10.1177/1474515119886155.

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Background: Delirium is a common postoperative complication after cardiac surgery. The relationship between delirium and cardiac function has not been fully elucidated. Aims: The aim of this study was to identify the association between preoperative cardiac function and delirium among patients after cardiac surgery. Methods: We prospectively recruited 635 cardiac surgery patients with a planned cardiac intensive care unit admission. Postoperative delirium was diagnosed using the confusion assessment method for the intensive care unit. Preoperative cardiac function was assessed using N-terminal prohormone of brain natriuretic peptide (NT-proBNP), New York Heart Association functional classification and left ventricular ejection fraction. Results: Delirium developed in 73 patients (11.5%) during intensive care unit stay. NT-proBNP level (odds ratio (OR) 1.24, 95% confidence interval (CI) 1.01–1.52) and New York Heart Association functional classification (OR 2.34, 95% CI 1.27–4.31) were both independently associated with the occurrence of delirium after adjusting for various confounders. The OR of delirium increased with increasing NT-proBNP levels after the turning point of 7.8 (log-transformed pg/ml). The adjusted regression coefficients were 1.19 (95% CI 0.95–1.49, P=0.134) for NT-proBNP less than 7.8 (log-transformed pg/ml) and 2.78 (95% CI 1.09–7.12, P=0.033) for NT-proBNP greater than 7.8 (log-transformed pg/ml). No association was found between left ventricular ejection fraction and postoperative delirium. Conclusion: Preoperative cardiac function parameters including NT-proBNP and New York Heart Association functional classification can predict the incidence of delirium following cardiac surgery. We suggest incorporating an early determination of preoperative cardiac function as a readily available risk assessment for delirium prior to cardiac surgery.

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Alton, Gwen Y., Soreh Taghados, Ari R. Joffe, Charlene M. T. Robertson, and Irina Dinu. "Prediction of preschool functional abilities after early complex cardiac surgery." Cardiology in the Young 25, no. 4 (April 30, 2014): 655–62. http://dx.doi.org/10.1017/s1047951114000535.

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AbstractBackground: It is important to identify early predictors of functional limitations in children after congenital heart surgery to optimise their independence as they prepare for school. The purpose of this study is to determine potentially modifiable predictor variables of functional abilities in pre-school children who underwent complex cardiac surgery at 6 weeks of age or earlier. Methods: This prospective inception cohort study comprised a sample of 165 survivors (63% boys) who had complex cardiac surgery (75% biventricular repairs) at Stollery Children’s Hospital, Edmonton, Alberta. We excluded children with chromosomal abnormalities. When children were 4–5 years of age, the parents completed the Adaptive Behavioral Assessment System II. Regression analysis was used to assess the association between multiple risk factors and each of the four continuous composite scores. Results: The mean scores for the practical domain and general adaptive composite score of the Adaptive Behavioural Assessment System were lower than the conceptual and social domains, with 13.3% of the children having a delay in the practical domain. There was a significant association between the general adaptive (p=0.003; 0.012), conceptual (p=0.0004; 0.042), social (p=0.0007; 0.028), and the practical (p=0.046; 0.003) domain composite scores with the mother’s education and preoperative plasma lactate, respectively. Conclusion: Maternal education may be a marker for the social context of children, and warrants societal attention to improve functional outcomes. Preoperative lactate as a potentially modifiable variable may warrant increased attention to early diagnosis and aggressive resuscitation of young infants with congenital heart disease.

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Bednar, Frantisek, Tomas Budesinsky, Hana Linkova, and Viktor Kocka. "Invasive Hemodynamic Assessment of Cardiac Output State after MitraClip Therapy in Nonanaesthetized Patients with Functional Mitral Regurgitation." BioMed Research International 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/6296972.

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Background. Surgical correction of mitral regurgitation (MR) can lead to postoperative low cardiac output state. We aimed to assess the acute hemodynamic changes after percutaneous MitraClip therapy (a unique model without influence of factors linked to surgical procedure) in patients with functional MR without the influence of general anaesthesia. Methods. We studied invasive hemodynamic parameters in 23 patients before procedure (conscious, nonsedated patients), during procedure (intubated patients), and the first day after MitraClip implantation (conscious, extubated patients). Results. Mitral valve clipping significantly increased cardiac index (CI) (from 2.0 ± 0.5 to 3.3 ± 0.6 L/min/m2; p<0.01). Conversely, there was significant reduction in the mean pulmonary capillary wedge pressure (PCWP) (from 18.6 ± 5.7 to 10.5 ± 3.8 mmHg; p<0.01), mean pulmonary artery pressure (from 29.8 ± 10.9 to 25.2 ± 10.3 mmHg; p=0.03), and pulmonary vascular resistance index (from 531 ± 359 to 365 ± 193 dyn·s·cm−5/m2; p=0.03). Conclusions. The functional MR therapy with percutaneous MitraClip device results in significant increase in CI (+66%) and concomitant decrease in PCWP (−42%). None of our patients developed low cardiac output state. Our results support the idea that significant part of low cardiac output state after cardiac surgery is due to surgery related factors rather than due to increase in afterload after MR elimination.

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Bernardino, Gabriel, Amir Hodzic, Hélène Langet, Damien Legallois, Mathieu De Craene, Miguel Ángel González Ballester, Éric Saloux, and Bart Bijnens. "Volumetric parcellation of the cardiac right ventricle for regional geometric and functional assessment." Medical Image Analysis 71 (July 2021): 102044. http://dx.doi.org/10.1016/j.media.2021.102044.

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Kepez, Alper, İlknur Aktaş, Zeynep Demet İlgezdi, Fatma Doğan Metin, Feyza Ünlü Özkan, Duygu Şilte, Meryem Yılmaz Kaysın, Kürşat Tigen, and Okan Erdoğan. "Assessment of Cardiac Functional Alterations of Ankylosing Spondylitis Patients without Cardiovascular Risk Factors." Kosuyolu Kalp Dergisi 16, no. 2 (August 14, 2013): 107–14. http://dx.doi.org/10.5578/kkd.4711.

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Heroux, A. L., P. Silverman, M. R. Costanzo, E. J. O'Sullivan, M. R. Johnson, Y. Liao, T. L. McKiernan, J. E. Balhan, F. S. Leya, and G. M. Mullen. "Intracoronary ultrasound assessment of morphological and functional abnormalities associated with cardiac allograft vasculopathy." Circulation 89, no. 1 (January 1994): 272–77. http://dx.doi.org/10.1161/01.cir.89.1.272.

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Collins, Jeremy D. "Global and Regional Functional Assessment of Ischemic Heart Disease with Cardiac MR Imaging." Radiologic Clinics of North America 53, no. 2 (March 2015): 369–95. http://dx.doi.org/10.1016/j.rcl.2014.11.001.

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Naito, Atsuhiko T., Masamichi Ito, Hiroko Izumi-Nakaseko, Kentaro Ando, Mihoko Hagiwara-Nagasawa, Yuji Nakamura, and Atsushi Sugiyama. "Assessment of the drug-induced cardiac functional toxicity by pattern-cultured hiPSC-CMs." Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (2018): PO3–11–13. http://dx.doi.org/10.1254/jpssuppl.wcp2018.0_po3-11-13.

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Arrich, J., F. Sterz, W. Behringer, and H. Herkner. "Functional assessment of cardiac arrest survivors: One month might not be long enough." Resuscitation 77 (May 2008): S70. http://dx.doi.org/10.1016/j.resuscitation.2008.03.214.

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Zhou, Ziwu, Fei Han, Takegawa Yoshida, Kim-Lien Nguyen, John Paul Finn, and Peng Hu. "Improved 4D cardiac functional assessment for pediatric patients using motion-weighted image reconstruction." Magnetic Resonance Materials in Physics, Biology and Medicine 31, no. 6 (July 24, 2018): 747–56. http://dx.doi.org/10.1007/s10334-018-0694-8.

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Reddy, P. Vijaya Narasimha, and R. Jaya Prakash Reddy. "Assessment of risk factors in cardiac failure after myocardial infarction." International Journal of Research in Medical Sciences 6, no. 6 (May 25, 2018): 1934. http://dx.doi.org/10.18203/2320-6012.ijrms20181962.

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Background: Cardiac failure is a clinical syndrome that may result from any structural or functional cardiac disorders that impairs the pumping ability of the heart. Post infarction cardiac failure is one of the common complications of Acute Myocardial Infarction which is influenced by factors like extent of MI, Life style, associated co-morbid conditions.Methods: The present study comprises of 50 cardiac failure patients with history of MI in the past and who presented with myocardial infarction with cardiac failure were included in this study. This study was conducted at Rajivgandhi Institute of Medical Sciences, Kadapa, YSR District, Andhra Pradesh. The study was carried out for a period of 2 years. Informed consent was taken from each and every patient included in the study.Results: In our study 42 (84%) are males and 8 (16%) are females. Out of 50 patients 37 (74%) are smokers and 32 (64%) are alcoholics. In our study maximum number of patients i.e. 60% of the patients are sedentary in nature. Among 42 male patients 28 are having WHR >0.9 and 8 female patients WHR >0.8 is quite significant.Conclusions: Post MI cardiac failure is more common in males and sedentary lifestyles. Smoking, alcohol consumption and associated co morbid conditions have linear relationship with incidence of post infarction Cardiac failure. Abdominal obesity has positive effect on incidence of post MI cardiac failure.

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Matunovic, Radomir, Aleksandar Stojanovic, Zdravko Mijailovic, Branko Gligic, and Andjelka Ristic-Angelkov. "Assessment of tissue viability for improvement of the left ventricular function after revascularization." Medical review 59, no. 3-4 (2006): 169–73. http://dx.doi.org/10.2298/mpns0604169m.

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Introduction. Treatment of patients with heart failure following myocardial infarction is still a clinical challenge. Drug therapy in these patients is limited, and invasive revascularization is not always successful and does not guarantee desired results. The aim of this study was to compare the effectiveness of invasive revascularization procedures (coronary artery bypass grafting - CABG or percutaneous transluminal coronary angioplasty - PICA) with conventional drug therapy in patients with heart failure after acute myocardial infarction in whom significant portion of viable myocardial tissue was detected during low dose dobutamine stress echocardiography. Material and methods. Using a prospective analysis, we investigated 66 patients with heart failure following myocardial infarction and reduced left ventricular ejection fraction (LVEF<35%). 34 patients underwen revascularization procedures including CABG or PTCA. The other 32 patients received only conventional drug therapy. The patients were followed during 12 months examing LVEF, left ventricular wall motion score index (WMSI), NYHA functional class, and cardiac death. Results. After 12 months, patients undergoing revascularization procedures presented with significantly better functional improvement of LVEF (37.84% vs. 33.14%, p<0.05), better clinical status and significantly less cardiac deaths (8.82% vs. 21.87%, p<0.01) in comparison to patients who stayed on drug therapy. After 12 months WMSI was significantly better in patients who underwent interventional therapy (l.69?Q7 vs. 1.82 ?04, p<0.01). Conclusion. After a 12-month follow up period, patients with presence of viable myocardial tissue after myocardial infarction and under?going revascularization procedures presented with better functional recovery and less cardiac events, including cardiac death, in comparison with patients who received only drug therapy.

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Weinstein, Adam S., Martin I. Sigurdsson, and Angela M. Bader. "Comparison of Preoperative Assessment of Patient’s Metabolic Equivalents (METs) Estimated from History versus Measured by Exercise Cardiac Stress Testing." Anesthesiology Research and Practice 2018 (September 3, 2018): 1–5. http://dx.doi.org/10.1155/2018/5912726.

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Background. Preoperative anesthetic evaluations of patients before surgery traditionally involves assessment of a patient’s functional capacity to estimate perioperative risk of cardiovascular complications and need for further workup. This is typically done by inquiring about the patient’s physical activity, with the goal of providing an estimate of the metabolic equivalents (METs) that the patient can perform without signs of myocardial ischemia or cardiac failure. We sought to compare estimates of patients’ METs between preoperative assessment by medical history with quantified assessment of METs via the exercise cardiac stress test. Methods. A single-center retrospective chart review from 12/1/2005 to 5/31/2015 was performed on 492 patients who had preoperative evaluations with a cardiac stress test ordered by a perioperative anesthesiologist. Of those, a total of 170 charts were identified as having a preoperative evaluation note and an exercise cardiac stress test. The METs of the patient estimated by history and the METs quantified by the exercise cardiac stress test were compared using a Bland–Altman plot and Cohen’s kappa. Results. Exercise cardiac stress test quantified METs were on average 3.3 METS higher than the METs estimated by the preoperative evaluation history. Only 9% of patients had lower METs quantified by the cardiac stress test than by history. Conclusions. The METs of a patient estimated by preoperative history often underestimates the METs measured by exercise stress testing. This demonstrates that the preoperative assessments of patients’ METs are often conservative which errs on the side of patient safety as it lowers the threshold for deciding to order further cardiac stress testing for screening for ischemia or cardiac failure.

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Vajauskas, Donatas, Vytė Valerija Maneikienė, Algirdas Edvardas Tamošiūnas, Kęstutis Ručinskas, Raminta Lukšaitė, and Evelina Balčiūnaitė. "Correlation of cardiac 123I-MIBG imaging with conventional markers of the heart failure." Seminars in Cardiovascular Medicine 20, no. 2 (December 1, 2014): 5–9. http://dx.doi.org/10.2478/semcard-2014-0002.

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Summary Objectives: Quantitative values of cardiac iodine-123 metaiodobenzylguanidine (123I-MIBG) global and regional adrenergic innervation showed promising results in predicting clinical course of heart failure. Nevertheless data is lacking how global and regional cardiac 123I-MIBG imaging parameters correlate with patient’s clinical data and conventional heart failure markers. Patients and methods: Eighty-six patientswith class II-IVNewYorkHeartAssociation (NYHA) heart failure were investigated. Patients underwent early and late cardiac 123I-MIBG planar and single photon emission computed tomography (SPECT) scanning. Global and regional cardiac 123I-MIBG scores were calculated and compared to conventional heart failure markers (left ventricular ejection fraction (LVEF), B-type natriuretic peptide (BNP) and maximum rate of oxygen consumption (VO2 max)), followed by NYHA functional class clinical assessment at the time of investigation. Results: Weak statistically significant correlation was noted between LVEF and global and regional cardiac adrenergic denervation scores, between BNP and VO2 max and global cardiac adrenergic denervation scores. Global and regional cardiac adrenergic denervation scores significantly differed within LVEF ranges. Global cardiac adrenergic denervation scores significantly differed within BNP levels and NYHA functional class. Conclusions: Conventional cardiac heart failure markers had weak correlation with global and regional cardiac 123I-MIBG imaging parameters. Cardiac 123I-MIBG imaging markers differed significantly depending on LVEF and BNP levels, and NYHA functional class.

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Mahnken, Andreas H. "Multidetector-row Computed Tomography in the Assessment of Coronary Artery Disease – New Techniques and Insights." European Cardiology Review 6, no. 2 (2010): 43. http://dx.doi.org/10.15420/ecr.2010.6.2.43.

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Over the last decade, cardiac computed tomography (CT) technology has experienced revolutionary changes and gained broad clinical acceptance in the work-up of patients suffering from coronary artery disease (CAD). Since cardiac multidetector-row CT (MDCT) was introduced in 1998, acquisition time, number of detector rows and spatial and temporal resolution have improved tremendously. Current developments in cardiac CT are focusing on low-dose cardiac scanning at ultra-high temporal resolution. Technically, there are two major approaches to achieving these goals: rapid data acquisition using dual-source CT scanners with high temporal resolution or volumetric data acquisition with 256/320-slice CT scanners. While each approach has specific advantages and disadvantages, both technologies foster the extension of cardiac MDCT beyond morphological imaging towards the functional assessment of CAD. This article examines current trends in the development of cardiac MDCT.

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Sumin, A. N. "Actual Issues of the Cardiac Complications Risk Assessment and Correction in Non-Cardiac Surgery." Rational Pharmacotherapy in Cardiology 16, no. 5 (November 4, 2020): 749–58. http://dx.doi.org/10.20996/1819-6446-2020-10-08.

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Worldwide, more than 200 million non-cardiac surgeries are performed annually, and this number is constantly increasing; cardiac complications are the leading cause of death in such surgeries. So, in a multicenter study conducted in 27 countries, cardiovascular complications were present in 68% of cases of death in the postoperative period. Registers of recent years have shown that the number of such complications remains high, for example, with a dynamic assessment of troponins, perioperative myocardial damage was detected in 13-18% of cases. This review provides a critical analysis of the step-by-step algorithm for assessing cardiac risk of non-cardiac operations considering the emergence of new publications on this topic. The review discusses new data on risk assessment scales, functional state assessment, the use of non-invasive tests, biomarkers, the role of preventive myocardial revascularization in the preoperative period, and drug therapy. The issues of non-cardiac operations after percutaneous coronary intervention, perioperative myocardial damage are considered separately. The review emphasizes the difficulties in obtaining evidence, conducting randomized clinical trials in this section of medicine, which do not allow obtaining unambiguous conclusions in most cases and lead to inconsistencies and ambiguities in the recommendations of various expert groups. This review will help practitioners navigate this issue and help to use the optimal diagnostic and treatment strategy before performing non-cardiac surgery.

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Asante-Korang, Alfred. "Echocardiographic evaluation before and after cardiac transplantation." Cardiology in the Young 14, S1 (February 2004): 88–92. http://dx.doi.org/10.1017/s1047951104006365.

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Transplantation of the heart remains a viable option not only as primary treatment for hypoplastic left heart syndrome, but also for end-stage problems after the Norwood sequence of palliations. In this review, I discuss the pre-operative, intra-operative, and post-operative echocardiographic evaluation of these patients, with special emphasis on hemodynamic and functional assessment as well as surveillance for rejection and coronary arterial disease.

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Cromhout, Pernille Fevejle, Selina Kikkenborg Berg, Philip Moons, Sune Damgaard, Samer Nashef, and Lau Caspar Thygesen. "Updating EuroSCORE by including emotional, behavioural, social and functional factors to the risk assessment of patients undergoing cardiac surgery: a study protocol." BMJ Open 9, no. 7 (July 2019): e026745. http://dx.doi.org/10.1136/bmjopen-2018-026745.

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IntroductionConventional risk assessment in cardiac surgery focus on medical and physiological factors and have been developed to predict mortality. Other relevant risk factors associated with increased risk of poor outcomes are not included. Adding non-medical variables as potential prognostic factors to risk assessments direct attention away from specific diagnoses towards a more holistic view of the patients and their predicament. The aim of this paper is to describe the method and analysis plan for the development and validation of a prognostic screening tool as a supplement to the European System for Cardiac Operative Risk Evaluation (EuroSCORE) to predict mortality, readmissions and prolonged length of admission in patients within 90 days after cardiac surgery, as individual outcomes.Methods and analysisThe development of a prognostic screening tool with inclusion of emotional, behavioural, social and functional factors complementing risk assessment by EuroSCORE will adopt the methods recommended by the PROGnosis RESearch Strategy Group and report using the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis statement. In the development stage, we will use data derived from three datasets comprising 1143, 3347 and 982 patients for a prospective cohort study of patients undergoing cardiac surgery, respectively. We will construct logistic regression models to predict mortality, prolonged length of admission and 90-day readmissions. In the validation stage, we will use data from a separate sample of 333 patients planned to undergo cardiac surgery to assess the performance of the developed prognostic model. We will produce validation plots showing the overall performance, area under the curve statistic for discrimination and the calibration slope and intercept.Ethics and disseminationThe study will follow the requirements from the Ethical Committee System ensuring voluntary participation in accordance with the Helsinki declarations. Data will be filed in accordance with the requirements of the Danish Data Protection Agency.

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GHISTA, DHANJOO N., LIANG ZHONG, THU-THAO LE, and RU-SAN TAN. "CARDIAC CONTRACTILITY MEASURES OF LEFT VENTRICULAR SYSTOLIC FUNCTIONAL ASSESSMENT OF NORMAL AND DISEASED HEARTS." Journal of Mechanics in Medicine and Biology 09, no. 04 (December 2009): 555–78. http://dx.doi.org/10.1142/s0219519409003139.

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Left ventricular (LV) contraction is the basis of LV systolic function, impairment of which underlies heart failure pathophysiology. Its accurate quantification in the form of LV contractility indices is imperative for diagnostic and follow-up assessment of LV systolic function in heart failure. Herein, we analyze LV contractile performance by focusing on LV contractility indices at different physiological organizational levels: from sarcomere dynamics to LV myocardial properties (such as elastic modulus and elastance), and from LV wall contractile stress development to the generation of intra-LV blood flow velocities and pressure distributions. Further, we present the development analyses of these indices and their medical applications. Using improved development of invasive and noninvasive techniques for measuring ventricular pressure, geometry, and volume, we show how these indices have become more amenable for clinical usage to obtain better patient assessment. The purpose of this paper is to present a comprehensive coverage of LV contraction physiology, indices to qualify LV contraction, formulation, and medical applications of some major intrinsic LV contractility indices, so as to provide the basis of functional assessment of normal versus diseased hearts.

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Panov, A. V., E. V. Kuleshova, N. L. Lokhovinina, M. Z. Alugishvili, I. T. Abesadze, I. V. Titenkov, and Yu A. Kudaev. "Assessment of cardiovascular risk and prevention of complications in non-cardiac surgery in patients with coronary heart disease." "Arterial’naya Gipertenziya" ("Arterial Hypertension") 26, no. 6 (January 18, 2021): 629–39. http://dx.doi.org/10.18705/1607-419x-2020-26-6-629-639.

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The incidence of cardiovascular complications in non-cardiac surgery is about 3 %. The review presents the data on the assessment of cardiovascular risk (CVR) in non-cardiac surgery. The algorithm of decisionmaking considers the functional state of the patient and the category of CVR of the upcoming surgery. Functional testing is not indicated for patients with low CVR. Stress tests should be considered in high-risk patients if the test results may change the perioperative drug therapy, the method of anesthesia, or the surgical approach. Routine coronary revascularization does not reduce perioperative risks and is used for special indications. Percutaneous coronary intervention and associated dual antiplatelet therapy may delay the timing of non-cardiac operations. Perioperative drug therapy (beta-blockers, aspirin, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers and statins) should be prescribed taking into account the individual risk of the patient.

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Tang, Chloe Pek Sang, Andre La Gerche, Julie McMullen, Erin Howden, Sasanka M. Handunnetti, Isaac Goncalves, Jenny Ooi, and Constantine S. Tam. "Prospective, Comprehensive Cardiac Assessment in Patients Receiving BTK Inhibitor Therapy." Blood 134, Supplement_1 (November 13, 2019): 4301. http://dx.doi.org/10.1182/blood-2019-129808.

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The development of Bruton Kinase Inhibitors (BTKi) has been a major advance in the treatment of chronic lymphocytic leukaemia and related B cell malignancies, but atrial fibrillation (AF) and sudden cardiac deaths are emerging as unique side effects of BTKi. The pathophysiology of cardiac side effects in BTKi treated patients is not known, and an excess of cardiac diseases is not exhibited in the congenital BTK deficiency population. Our group has previously shown in cell models that ibrutinib inhibits the phosphoinositide 3-kinase (PI3K)-AKT pathway in the heart, providing a potential explanation for cardiotoxicity. The PI3K pathway is the major cardioprotective mechanism in the heart under stress conditions, and mice with cardiomyopathy and reduced PI3K can display AF, ventricular arrhythmias and develop severe cardiomyopathy. Concerningly, given the above information, cardiac surveillance has not been routinely incorporated in BTKi trials. We therefore sought to prospectively and systemically assess cardiac function and rhythm in patients commencing BTKi therapy. Method: This is a prospective, multicentre study with the aim of conducting comprehensive cardiac assessment of patients commencing BTKi. This assessment involved 2 domains: 1) detection of subclinical arrhythmias by performing baseline and 3 month follow-up Holter Monitor testing, 2) quantification of subclinical structural changes including dynamic atrial and ventricular contractile function using transthoracic echocardiogram (TTE) and exercise cardiac magnetic resonance imaging (MRI) at baseline and 3 months. The primary outcome assessed was significant reduction in left atrial(LA) volume as a measure of ibrutinib-induced myocardial dysfunction. A 12.5% difference in LA volume is clinically meaningful given that it has been associated with greater AF risk in predisposed individuals. A sample size of 40 provides adequate power of 0.8, α = 0.05 for detecting a 12.5% increase in LA volume from an expected baseline of -18±3. Secondary outcomes measured were: 1) Reduction in ventricular ejection fraction during exercise cardiac MRI, 2) reduction in VO2 max on cardiopulmonary exercise testing. Results: A total number of 40 patients with median age of 68 years were recruited over median follow-up of 12 months (Table 1). 6/40 patients demonstrated significant reduction in left atrial volume at 3 month follow-up. They were not clinically symptomatic and did not have co-existing history of AF. Functional testing with VO2 max on cardiopulmonary exercise testing showed significant reduction in VO2 max in 8/40 patients. There were no significant reduction in ventricular ejection fraction during exercise cardiac MRI. 1/40 patients developed symptomatic AF 257 days after commencing ibrutinib and symptoms were controlled with a beta blocker. He had normal baseline TTE but was found to have enlargement of LA volume during follow-up. One patient with Waldenstrom Macroglobulinameia with normal baseline cardiac testing died from presumed ventricular tachycardia 3 months after commencing trial drug, before reassessment could be conducted. Overall, our data indicated that despite thorough cardiac surveillance, no significant cardiac abnormalities were detected at 3 month follow-up. Conclusion: This prospective and comprehensive cardiac study demonstrated no significant evidence of functional, structural or rhythm abnormalities at 3 month follow-up of patients commencing BTKiinhibitor, as assessed by Holter monitor, exercise cardiac MRI, cardiopulmonary testing and transthoracic echocardiography. Longer follow-up and additional electrophysiological studies may be required to further delineate the cause of BTKi induced cardiotoxicity. Disclosures McMullen: CLL Global Research Funding: Research Funding. Handunnetti:Gilead: Honoraria; Abbvie: Other: Travel Grant. Tam:Abbvie, Janssen: Research Funding; Abbvie, Janssen, Beigene, Roche, Novartis: Honoraria.

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Barczuk-Falęcka, Marzena, Łukasz A. Małek, Hubert Krysztofiak, Danuta Roik, and Michał Brzewski. "Cardiac Magnetic Resonance Assessment of the Structural and Functional Cardiac Adaptations to Soccer Training in School-Aged Male Children." Pediatric Cardiology 39, no. 5 (March 8, 2018): 948–54. http://dx.doi.org/10.1007/s00246-018-1844-5.

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Bossone, Eduardo, Filippo Cademartiri, Hani AlSergani, Salvatore Chianese, Rahul Mehta, Valentina Capone, Carlo Ruotolo, et al. "Preoperative Assessment and Management of Cardiovascular Risk in Patients Undergoing Non-Cardiac Surgery: Implementing a Systematic Stepwise Approach during the COVID-19 Pandemic Era." Journal of Cardiovascular Development and Disease 8, no. 10 (October 3, 2021): 126. http://dx.doi.org/10.3390/jcdd8100126.

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Major adverse cardiac events, defined as death or myocardial infarction, are common causes of perioperative mortality and major morbidity in patients undergoing non-cardiac surgery. Reduction of perioperative cardiovascular risk in relation to non-cardiac surgery requires a stepwise patient evaluation that integrates clinical risk factors, functional status and the estimated stress of the planned surgical procedure. Major guidelines on preoperative cardiovascular risk assessment recommend to establish, firstly, the risk of surgery per se (low, moderate, high) and the related timing (elective vs. urgent/emergent), evaluate the presence of unstable cardiac conditions or a recent coronary revascularization (percutaneous coronary intervention or coronary artery bypass grafting), assess the functional capacity of the patient (usually expressed in metabolic equivalents), determine the value of non-invasive and/or invasive cardiovascular testing and then combine these data in estimating perioperative risk for major cardiac adverse events using validated scores (Revised Cardiac Risk Index (RCRI) or National Surgical Quality Improvement Program (NSQIP)). This stepwise approach has the potential to guide clinicians in determining which patients could benefit from cardiovascular therapy and/or coronary artery revascularization before non-cardiac surgery towards decreasing the incidence of perioperative morbidity and mortality. Finally, it should be highlighted that there is a need to implement specific strategies in the 2019 Coronavirus disease (COVID-19) pandemic to minimize the risk of transmission of COVID-19 infection during the preoperative risk assessment process.

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Journal articles on the topic 'Cardiac Functional Assessment'

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