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1

Aina-Badejo, Danielle. Elucidating the Unknown Role of Cyclin Dependent Kinase 5 in Cardiac Pathophysiological Conditions. [publisher not identified], 2021.

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2

Shave, Robert E. The impact of exercise duration and environmental conditions upon the incidence of exercise induced cardiac fatigue (EICF). University of Wolverhampton, 2003.

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3

Rath, Matthias. Why animals don't get heart attacks-- but people do!: The discovery that will eradicate heart disease : the natural prevention of heart attacks, strokes, high blood pressure, diabetes, high cholesterol and many other cardiovascular conditions. 4th ed. MR Pub., 2003.

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4

G, Yanowitz Frank, and Wilson Philip K, eds. Cardiac rehabilitation, adult fitness, and exercise testing. 3rd ed. Williams & Wilkins, 1995.

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5

Fardy, Paul S. Cardiac rehabilitation, adult fitness, and exercise testing. 2nd ed. Lea & Febiger, 1988.

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6

Bernis: Le cardinal des plaisirs. Gallimard, 1998.

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7

Bergin, Joseph. Cardinal Richelieu: Power and the pursuit of wealth. Yale University Press, 1985.

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8

Morgan, Rhodri. Cardiff: Half-and-half a capital. Gomer, 1994.

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9

Cardiff Bay Opera House Trust. Cardiff Bay Opera House architectural competition =: Cystadleuaeth Bensaernïol T^y Opera Bae Caerdydd : competition conditions and design brief. s.n.], 1994.

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10

Martin, Nicholas. Cardiac MRI. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0034.

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Magnetic resonance imaging (MRI) is an important tool for investigating congenital cardiac conditions. It provides excellent images of the cardiac anatomy and is unrivalled in its ability to illuminate the pulmonary vessels. Conservation of femoral vessels and absence of ionizing radiation gives it an advantage over cardiac catheterization. Apart from the challenges of anesthetizing a child with an uncorrected congenital heart condition, the MRI environment presents some unique challenges to the anesthesiologist. It is usually remote from the main operating suite, and the permanent strong magn
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11

Kisiel, Maria, and Alison Smith. Cardiac surgery. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199642663.003.0026.

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Coronary heart disease is caused by the build-up of atherosclerotic plaques which, over time, narrow the lumen of the coronary arteries. Acute coronary syndrome describes a spectrum of conditions caused by coronary artery disease; these are unstable angina, ST-elevation myocardial infarction (STEMI), and non-ST-elevation myocardial infarction (NSTEMI). Coronary artery disease is the leading cause for cardiac surgical interventions, but other causes are hypertension, valve disease, arrhythmias, cardiomyopathies, infections, and congenital abnormalities. This chapter provides an overview of the
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12

Lancellotti, Patrizio, and Bernard Cosyns. Cardiac Source of Embolism (SOE) and Cardiac Masses. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713623.003.0014.

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Embolism of cardiac origin accounts for around 15–30 per cent of ischaemic strokes. The diagnosis of a cardio-embolic source of stroke is frequently uncertain and relies on the identification of a potential cardiac source of embolism in the absence of significant cerebrovascular occlusive disease. In this respect, echocardiography (both transthoracic and/or transoesophageal) serves as a cornerstone in the evaluation, diagnosis, and managementof these patients. A clear understanding of the various types of cardiac conditions associated with cardio-embolic stroke and their intrinsic risk is ther
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13

Iskandrian, Ami E., and Ernest V. Garcia, eds. Nuclear Cardiac Imaging. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199392094.001.0001.

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Nuclear cardiac imaging refers to cardiac radiological diagnostic techniques performed with the aid of radiopharmaceuticals, which are perfused into the myocardium as markers. These imaging studies provide a wide range of information about the heart, including the contractility of the heart, the amount of blood supply to the heart and whether parts of the heart muscle are alive or dead. This is essential information for cardiologists, and nuclear imaging has become an increasingly important part of the cardiologist's armamentarium. Chapters in Nuclear Cardiac Imaging cover historical, technica
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14

Yoris, Adrián, Adolfo M. García, Paula Celeste Salamone, Lucas Sedeño, Indira García-Cordero, and Agustín Ibáñez. Cardiac interoception in neurological conditions and its relevance for dimensional approaches. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198811930.003.0010.

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Dimensional and transdiagnostic approaches have revealed multiple cognitive/emotional alterations shared by several neuropsychiatric conditions. While this has been shown for externally triggered neurocognitive processes, the disruption of interoception across neurological disorders remains poorly understood. This chapter aims to fill this gap while proposing cardiac interoception as a potential common biomarker across disorders. It focuses on key aspects of interoception, such as the mechanisms underlying different interoceptive dimensions; the relationship among interoception, emotion, and s
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15

Madhuri, GB. Textbook of Physiotherapy for Cardiorespiratory Cardiac Surgery & Thoracic Surgery Conditions. Jaypee Brothers Medical Publishers (P) Ltd., 2008. http://dx.doi.org/10.5005/jp/books/10946.

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16

Madhuri, G. B. Textbook of Physiotherapy for Cardio-Respiratory Cardiac Surgery and Thoracic Surgery Conditions. Jaypee Brothers Medical Publishers, 2008.

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17

Creasia, Joan Labelle. FACTORS ASSOCIATED WITH HEALTH OUTCOMES OF PATIENTS HOSPITALIZED WITH SELECTED CARDIAC CONDITIONS. 1987.

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18

Medforth, Janet, Linda Ball, Angela Walker, Sue Battersby, and Sarah Stables. Medical conditions during pregnancy. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198754787.003.0010.

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This chapter comprises a review of common medical conditions, including asthma, thyroid conditions, cardiac conditions, and renal diseases. There is a small section on renal transplant and care of the woman during pregnancy. Insulin-dependent diabetes, non-insulin-dependent diabetes, gestational diabetes, and their impact on pregnancy are discussed. The effect of pregnancy on the conditions themselves is reviewed, along with recognition and management of pregnancy changes due to the condition. Pregnancy management options, including altered physiology and pharmacological treatment, are discuss
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19

Presbitero, Patrizia, Dennis Zavalloni, and Benedetta Agnoli. Cardiac emergencies in pregnancy. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0063.

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Cardiac diseases are an increasingly important cause of morbidity and mortality in pregnant women. Pregnancy leads to several changes in physiological processes, and the cardiovascular system progressively adapts to modifications that may worsen pre-existing pathological conditions or unmask previously undiagnosed diseases. Furthermore, pregnancy may be complicated by specific pathologies, which are harmful for patients with cardiac diseases. Admission to the intensive cardiac care unit is a rare event (0.1–0.9% of deliveries), but mortality rates range from 3.5% to 21%. When treating pregnant
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20

Lancellotti, Patrizio, and Bernard Cosyns. Systemic Disease and Other Conditions. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713623.003.0017.

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This chapter describes the effect of various activities on the heart and associated disorders. It details the echocardiographic findings of athlete’s heart and differential diagnosis. It considers pregnancy which induces several haemodynamic changes: increase in heart rate, stroke volume, cardiac output, and decrease in systemic vascular resistance. Several echocardiographic changes may also present in normal pregnancy and these must be recognized. Echocardiography should be performed in each pregnant woman with cardiac signs or symptoms to search for new cardiac disease occurring during pregn
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21

Demetriades, Demetrios, Leslie Kobayashi, and Lydia Lam. Cardiac complications in trauma. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0062.

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Post-traumatic cardiac complications may occur after penetrating or blunt injuries to the heart or may follow severe extracardiac injuries. The majority of victims with penetrating injuries to the heart die at the scene and do not reach hospital care. For those patients who reach hospital care, an immediate operation, sometimes in the emergency room, cardiac injury repair, and cardiopulmonary resuscitation provide the only possibility of survival. Many patients develop perioperative cardiac complications such as acute cardiac failure, cardiac arrhythmias, coronary air embolism, and myocardial
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22

Demetriades, Demetrios, Leslie Kobayashi, and Lydia Lam. Cardiac complications in trauma. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0062_update_001.

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Post-traumatic cardiac complications may occur after penetrating or blunt injuries to the heart or may follow severe extracardiac injuries. The majority of victims with penetrating injuries to the heart die at the scene and do not reach hospital care. For those patients who reach hospital care, an immediate operation, sometimes in the emergency room, cardiac injury repair, and cardiopulmonary resuscitation provide the only possibility of survival. Many patients develop perioperative cardiac complications such as acute cardiac failure, cardiac arrhythmias, coronary air embolism, and myocardial
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23

Lam, Lydia, Leslie Kobayashi, and Demetrios Demetriades. Cardiac complications in trauma. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0062_update_002.

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Post-traumatic cardiac complications may occur after penetrating or blunt injuries to the heart or may follow severe extracardiac injuries. The majority of victims with penetrating injuries to the heart die at the scene and do not reach hospital care. For those patients who reach hospital care, an immediate operation, sometimes in the emergency room, cardiac injury repair, and cardiopulmonary resuscitation provide the only possibility of survival. Many patients develop perioperative cardiac complications such as acute cardiac failure, cardiac arrhythmias, coronary air embolism, and myocardial
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24

Lam, Lydia, Leslie Kobayashi, and Demetrios Demetriades. Cardiac complications in trauma. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0062_update_003.

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Post-traumatic cardiac complications may occur after penetrating or blunt injuries to the heart or may follow severe extracardiac injuries. The majority of victims with penetrating injuries to the heart die at the scene and do not reach hospital care. For those patients who reach hospital care, an immediate operation, sometimes in the emergency room, cardiac injury repair, and cardiopulmonary resuscitation provide the only possibility of survival. Many patients develop perioperative cardiac complications such as acute cardiac failure, cardiac arrhythmias, coronary air embolism, and myocardial
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25

Ruiz-Villalba, Adrián, Nikolaos Frangogiannis, and José Maria Pérez-Pomares. Origin and diversity of cardiac fibroblasts: developmental substrates of adult cardiac fibrosis. Edited by José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0012.

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Cardiac connective tissues are primarily formed by cardiac fibroblasts (CF) of diverse embryonic origins. Whereas CF specific roles in cardiac morphogenesis remain under-researched, their involvement in adult cardiac fibrosis is clinically relevant. Cardiac fibrosis is a common element of several chronic cardiac conditions characterized by the loss of ventricular wall mechanical function, ultimately driving to heart failure. In the ischaemic heart early reparative fibrosis evidences the very restricted regenerative potential of the myocardium. In non-ischaemic diseases fibrosis is activated by
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26

Katritsis, Demosthenes G., Bernard J. Gersh, and A. John Camm. Conduction disease in specific conditions. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199685288.003.1501_update_002.

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27

Griffiths, Mark. Management of Cardiovascular Conditions of Adults in Acute Care. Blackwell Publishers, 2008.

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28

Thorne, Sara, and Paul Clift, eds. Rare conditions presenting in adulthood. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199228188.003.0026.

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Coronary anomalies 190Sinus of valsalva aneurysm 192 See Table 15.1.• Rare.• Occur in isolation or with associated congenital cardiac lesions.• Clinical significance depends on potential of the anomaly to cause ischaemia and sudden death.• Ischaemia is main indication for surgical repair and is associated with:...
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29

A Physical assessment of the Philips DCI-S digital cardiac imaging system under field conditions. Department of Health, Medical Devices Directorate, 1992.

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30

Morley, Peter Thomas. Pathophysiology and causes of cardiac arrest. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0061.

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Sudden cardiopulmonary arrest (CPA) is still the commonest cause of death globally. CPAs are usually categorized according to where they occur, with out-of-hospital arrests accounting for approximately 75% of CPA deaths and in-hospital the remaining 25%. The arrests are also sub-categorized according to the initial rhythm, with the best outcomes associated with shockable rhythms. Large registries have demonstrated a variable incidence of out-of-hospital CPAs in adults (50–150/100,000 person years), with a range of outcomes (3–16% survival to hospital discharge). The majority of CPAs in adults
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31

Mavrides, Nicole, and Charles Nemeroff. Biological Effects of Depression in Cardiac Illness. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190603342.003.0004.

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Both depression and cardiac disease are extremely common medical conditions, both separately and together. Depression in patients with cardiovascular disease (CVD) and coronary artery disease (CAD) has long been associated with poor functional and cardiovascular outcomes. Studies for the past 20 years have demonstrated that not only can depression affect the risk of CAD, but so can anxiety, panic, personality types, trauma, and stress. More recently, the studies have focused more on the pathophysiological processes that can characterize depression in cardiac disease; such as inflammation, hear
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32

Hagendorff, Andreas. Systemic diseases and other conditions: introduction. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0054.

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Cardiac structures and their function as well as the vascular system can be affected by general systemic influences. Exceptional physiological conditions like competitive sports or pregnancy cause typical, but normally reversible alterations in the heart. Certain systemic diseases will cause cardiovascular alteration and damage, which can be life-threatening or can introduce the development of myocardial failure due to humoral, immunological, or inflammatory affections on the myocardium or the valves. In the following chapters in this section, the echocardiographic findings which can be docume
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33

Scott, Jillian. Cycling for Heart Health: A Comprehensive Guide to Managing Cardiac and AFIB Conditions with Biking Exercises. Independently Published, 2022.

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34

O’Mahony, Constantinos. Hypertrophic cardiomyopathy: prevention of sudden cardiac death. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198784906.003.0354.

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Sudden cardiac death (SCD) secondary to ventricular arrhythmias is the most common mode of death in hypertrophic cardiomyopathy (HCM) and can be effectively prevented with an implantable cardioverter defibrillator (ICD). The risk of SCD in HCM relates to the severity of the phenotype and regular risk stratification is an integral part of routine clinical care. For the primary prevention of SCD, risk stratification involves the assessment of seven readily available clinical parameters (age, maximal left ventricular wall thickness, left atrial diameter, left ventricular outflow tract gradient, n
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35

Dawson, Ellen Adele. The impact of exercise duration, exercise intensity, fitness and environmental conditions on the development of exercise induced cardiac fatigue (E.I.C.F.). 2003.

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36

Ranucci, Marco, Serenella Castelvecchio, and Andrea Ballotta. Perioperative management of the high-risk surgical patient: cardiac surgery. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0077.

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During the last decade, as a result of continually improving surgical strategy and the technology which supports it (e.g. anaesthesia), cardiac surgery is offered to patients with advanced age and those with increasingly complex co-existing conditions that were previously considered to be contraindications. In addition, an increasing number of patients have previously undergone angioplasty, thereby delaying their initial coronary artery bypass graft surgery to a more advanced age. In general, candidates for cardiac surgery may now be not only older than in the past, but also more likely to hav
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37

Ranucci, Marco, Serenella Castelvecchio, and Andrea Ballotta. Perioperative management of the high-risk surgical patient: cardiac surgery. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199687039.003.0077_update_001.

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During the last decade, as a result of continually improving surgical strategy and the technology which supports it (e.g. anaesthesia), cardiac surgery is offered to patients with advanced age and those with increasingly complex co-existing conditions that were previously considered to be contraindications. In addition, an increasing number of patients have previously undergone angioplasty, thereby delaying their initial coronary artery bypass graft surgery to a more advanced age. In general, candidates for cardiac surgery may now be not only older than in the past, but also more likely to hav
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38

Ranucci, Marco, Serenella Castelvecchio, and Andrea Ballotta. Perioperative management of the high-risk surgical patient: cardiac surgery. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199687039.003.0077_update_002.

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During the last decade, as a result of continually improving surgical strategy and the technology which supports it (e.g. anaesthesia), cardiac surgery is offered to patients with advanced age and those with increasingly complex co-existing conditions that were previously considered to be contraindications. In addition, an increasing number of patients have previously undergone angioplasty, thereby delaying their initial coronary artery bypass graft surgery to a more advanced age. In general, candidates for cardiac surgery may now be not only older than in the past, but also more likely to hav
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39

Ranucci, Marco, Serenella Castelvecchio, and Andrea Ballotta. Perioperative management of the high-risk surgical patient: cardiac surgery. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0077_update_003.

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During the last decade, as a result of continually improving surgical strategy and the technology which supports it (e.g. anaesthesia), cardiac surgery is offered to patients with advanced age and those with increasingly complex co-existing conditions that were previously considered to be contraindications. In addition, an increasing number of patients have previously undergone angioplasty, thereby delaying their initial coronary artery bypass graft surgery to a more advanced age. In general, candidates for cardiac surgery may now be not only older than in the past, but also more likely to hav
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40

The use of TENS for non-painful conditions. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199673278.003.0010.

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Peripheral nerves consist of afferent and efferent neurones with different functions. TENS can be used to excite somatic efferents to influence the activity of skeletal muscle, and autonomic efferents to influence the activity of smooth muscle, cardiac muscle, and glands. There are physiological rationale to support the use of TENS to manage various non-painful conditions. Clinical experience suggests TENS is often beneficial. The purpose of this chapter is to describe the mechanism of action, clinical use and clinical efficacy for TENS when used to manage non-painful conditions. The chapter c
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41

D’Andrea, Antonello, André La Gerche, and Christine Selton-Suty. Systemic disease and other conditions: athlete’s heart. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0055.

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The term ‘athlete’s heart’ refers to the structural, functional, and electrical adaptations that occur as a result of habitual exercise training. It is characterized by an increase of the internal chamber dimensions and wall thickness of both atria and ventricles. The athlete’s right ventricle also undergoes structural, functional, and electrical remodelling as a result of intense exercise training. Some research suggests that the haemodynamic stress of intense exercise is greater for the right heart and, as a result, right heart remodelling is slightly more profound when compared with the lef
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42

Pasquet, Agnes, Marcia Barbosa, and Jo-Nan Liao. Systemic disease and other conditions: the heart during pregnancy. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0056.

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Normal pregnancy represents a haemodynamic challenge for the heart. The main changes are increases in blood (plasma) volume and cardiac output, and a decrease in systemic vascular resistance. These change start early during pregnancy and will be maximal around the 24th week of gestation. This translates into echocardiographic changes such as increase in ventricular volume, stroke volume, and changes in geometry. Peripartum cardiomyopathy is a left ventricular dysfunction without any underlying cause, arising near the end of the gestation or in the early postpartum period. Echocardiography is t
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43

McKenzie, Ian. Single Ventricle Physiology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0031.

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Congenital cardiac abnormalities in which there is functionally only a single ventricle are a heterogeneous group of conditions. These include patients with marked hypoplasia of one ventricle, usually with hypoplasia or atresia of the inflow of the ventricle, such as in hypoplastic left heart syndrome or conditions where surgical separation of the flow to each ventricle is not possible, such as double-inlet left ventricle. The most common pathway for palliating these conditions will be to use cavopulmonary connections to provide lung blood flow direct from systemic venous return (reliant on sy
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44

Gardiner, Matthew D., and Neil R. Borley. Cardiothoracic surgery. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199204755.003.0002.

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This chapter begins by discussing the basic principles of cardiac physiology and respiratory physiology, before focusing on the key areas of knowledge, namely congenital heart disease, coronary artery bypass grafting, heart valve disease, thoracic aortic dissection, thoracic aortic aneurysm, miscellaneous cardiac and mediastinal conditions, lung cancer, and miscellaneous thoracic conditions. The chapter concludes with relevant case-based discussions.
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45

Trivedi, Premal M., and Pablo Motta. Tetralogy of Fallot. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0027.

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Congenital heart conditions can be characterized as cyanotic or acyanotic. This chapter discusses one of the most common cyanotic congenital cardiac conditions: tetralogy of Fallot. Tetralogy of Fallot is composed of distinct anomalies which result in left-to-right shunting of blood resulting in cyanotic spells, under certain conditions such as pain (and associated tachycardia) decreased oxygenation, decreased venous return, or hypotension. Recognizing factors that accentuate the left-to-right shunting of blood in this condition is essential for adequate management of a TET spell which is freq
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46

Ramrakha, Punit, and Jonathan Hill, eds. Oxford Handbook of Cardiology. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199643219.001.0001.

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47

Saeed, Sahrai, and Eva Gerdts. Echocardiography. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198722366.003.0010.

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Current guidelines recommend extensive cardiovascular imaging in patients who experience ischaemic stroke or a transient ischaemic attack to prevent recurrent stroke. High-quality echocardiography is crucial for detection of the wide range of cardiac and proximal aortic conditions that can predispose to cerebral embolism. These conditions may be classified as major, minor, or uncertain risk sources of embolism. Although both transthoracic (TTE) and transoesophageal echocardiography (TOE) have substantial clinical utility in patients with cryptogenic stroke, these methods offer complementary in
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48

Morar, Nadia. Fast to Burn Fat with Low Fat Cookbook: A Low Fat Cookbook with over 100+ Quick and Easy Recipes for People with Cardiovascular Disease, High Blood Pressure, or Other Cardiac-Related Conditions. Independently Published, 2022.

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49

Morley-Smith, Andrew C., André R. Simon, and John Pepper. Implanted cardiac support devices. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199687039.003.0031.

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Mechanical circulatory support forms a crucial and expanding element of advanced heart failure management. Short-term assistance is delivered in emergency situations or where the underlying condition is likely to quickly worsen, and these approaches are discussed in Chapter 30. This chapter focuses on implantable devices intended for the medium and long term. The first half of the chapter is aimed directly at practical clinical management, whilst the second half considers the evidence base for contemporary practice. The chapter concludes by considering new paradigms for implantable cardiac sup
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50

Morley-Smith, Andrew C., André R. Simon, and John Pepper. Implanted cardiac support devices. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199687039.003.0031_update_001.

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Mechanical circulatory support forms a crucial and expanding element of advanced heart failure management. Short-term assistance is delivered in emergency situations or where the underlying condition is likely to quickly worsen, and these approaches are discussed in Chapter 30. This chapter focuses on implantable devices intended for the medium and long term. The first half of the chapter is aimed directly at practical clinical management, whilst the second half considers the evidence base for contemporary practice. The chapter concludes by considering new paradigms for implantable cardiac sup
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