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Journal articles on the topic 'Carcinoma Endometrio'

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1

Morán Mejía, Javier Alberto, Rosario Velásquez, Victor Argueta, and Roberto Orozco. "Carcinoma endometriode sincrónico que afecta útero y trompa uterina." Revista médica (Colegio de Médicos y Cirujanos de Guatemala) 159, no. 1 (2020): 41–43. http://dx.doi.org/10.36109/rmg.v159i1.173.

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La aparición de tumores sincrónicos en el aparato genital femenino es infrecuente. Se conoce poco sobre la presentación simultánea de carcinomas endometrioides del endometrio y la trompa uterina. Presentamos un caso de una paciente femenina de 38 años, nulípara, con historia de hemorragia vaginal de un mes de evolución, a quien se le realizó histerectomía y salpingooforectomía izquierda, donde el estudio anatomopatológico definitivo fue carcinoma endometriode de endometrio y de trompa uterina sincrónico.
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2

Cruz Muñóz, Héctor. "Sobre el diagnóstico, pronóstico y tratamiento del carcinoma endometrial." Revista Peruana de Ginecología y Obstetricia 12, no. 3 (2015): 324–72. http://dx.doi.org/10.31403/rpgo.v12i884.

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El diagnóstico clínico del carcinoma endometrial en sus estadíos iniciales es muy difícil porque ni la sintomatología ni el examen objetivo proporcionan elementos de juicio lo suficientemente característicos como para poder afirmarlo con alguna certeza. El síntoma que hace pensar siempre en una neoplasia maligna del endometrio es la metrorragia que ocurre en una mujer que está en la época post-menopáusica, pero este síntoma no es de manera alguna propia del carcinoma endometrial desarrollado en este período de la vida. En efecto, en un estudio efectuado en la Clínico Ginecológica Universitaria
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3

Aqueche, Gabriela, and Marisol Gramajo. "Carcinoma de células escamosas primario de endometrio." Revista médica (Colegio de Médicos y Cirujanos de Guatemala) 160, no. 3 (2021): 298–300. http://dx.doi.org/10.36109/rmg.v160i3.382.

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El carcinoma de células escamosas primario de endometrio, es una entidad poco común, que para ser considerado como primario debe llenar los criterios de Fluhmman, de 1928: 1) ausencia simultánea de adenocarcinoma, 2) que no haya continuidad entre el tumor endometrial y el epitelio que reviste el cuello uterino y 3) comprobar que no exista proliferación de un carcinoma primario de células escamosas del cuello. Se presenta el caso de mujer de 80 años quien consulta a la emergencia de ginecología por hemorragia vaginal de 5 días.
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4

Díaz, Juan, Marco Martell, Jorge Pomatanta, Luz Cisneros, Guillermo Fonseca, and Rafael Roeder. "Carcinoma de endometrio: cuadro clínico-patológico." Revista Peruana de Ginecología y Obstetricia 43, no. 3 (2015): 202–8. http://dx.doi.org/10.31403/rpgo.v43i1072.

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Con la finalidad de identificar el cuadro clínico patológico y determinar el estadío clínico, se analizó retrospectivamente información de 38 pacientes con carcinoma de endometrio admitidas al hospital Belén, Trujillo, Perú, desde 1966 a 1996. La edad promedio en la serie total fue 53,1 ± 11,4 años (rango, 22 a 8,3 años).La edad media de presentación de la menarquía fue 13,4 ± 1,6 años y de la menopausia (n=25) 48,2 ± 3,6 años. Once pacientes, fueron nulíparas (28,9%), cinco (13,2%) presentaron ovario poliquístico, cuatro (10,5%) tuvieron historia previa de hipertensión arterial, dos (5,3%) di
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5

Wood, Juan, Alfredo Durán, Sergio Fuensalida, and Alberto Guzmán. "Relación entre la hiperplasia endometrial y el adenocarcinoma del endometrio." Revista Peruana de Ginecología y Obstetricia 1, no. 2 (2015): 1–13. http://dx.doi.org/10.31403/rpgo.v1i896.

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El material histopatológico que se considera en esta ocasión demuestra que la hiperplasia endometrial, como manifestación de un estado estrogénico persistente e incontrarrestado, desempeña un rol importante en la génesis del carcinoma endometria1. Las imágenes histológicas en estas circunstancias pueden corresponder a una hiperplasia glándulo-quística o a una hiperplasia adenomatosa. La hiperplasia endometrial glándulo-quística durante la menacma y el climaterio premenopáusico, reflejo de desequilibrios endocrinos, no tiene mayor importancia en estos períodos, pero cuando se hace presente en l
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6

Aguilar, Ceny. "Carcinoma de Endometrio de Casos." Anales de la Facultad de Medicina 56, no. 1 (2014): 17. http://dx.doi.org/10.15381/anales.v56i1.4918.

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El carcinoma de endometrio es un tumor maligno originado a expensas del epitelio, el que resultaría ser consecuencia de un hiperestronismo relativo o absoluto. Según algunos autores, pasaría por una gama de lesiones preliminares como las hiperplasias adenomatosas. En nuestro trabajo, revisamos 62 casos diagnosticados microcóspicamente en el Servicio de Anatomía Patológica del Hospital Daniel A. Carrión en sus 24 años de funcionamiento. El 75% refirió ginecorragia de más de un mes de evolución: el 68% de casos corresponde a mujeres puérperas, nulíparas o con baja paridad. Al examen físico, en l
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7

Elmore, Lynne W., Kelly Domson, Jonathan R. Moore, Michael Kornstein, and R. Tucker Burks. "Expression of c-Kit (CD117) in Benign and Malignant Human Endometrial Epithelium." Archives of Pathology & Laboratory Medicine 125, no. 1 (2001): 146–51. http://dx.doi.org/10.5858/2001-125-0146-eockci.

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Abstract Background.—The proto-oncogene c-kit encodes a tyrosine kinase receptor (CD117) with a molecular weight of 145 kd. Previous studies, predominantly utilizing immunohistochemistry, have led to contradictory findings regarding the expression of CD117 in the endometrium. To help resolve this issue, we analyzed a series of benign and malignant endometrial tissues using both immunohistochemistry and Western blot analysis. Objective.—To examine the expression of CD117 in benign and malignant human endometrial tissues. Methods.—The expression of CD117 in 35 benign endometrial tissues (7 hyper
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8

Pérez Montiel, Camilo, María Murillo Salas, César Redondo Bermúdez, and Katherine Redondo de Oro. "Endometritis xantogranulomatosa asociada a carcinoma escamocelular de cérvix: presentación de un caso y revisión de la literatura." Revista Ciencias Biomédicas 8, no. 2 (2020): 105–10. http://dx.doi.org/10.32997/rcb-2019-2877.

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Introducción: la endometritis xantogranulomatosa es un proceso inflamatorio raro del endometrio, que se caracteriza por la presencia de abundantes histiocitos espumosos asociados a células inflamatorias mixtas. La importancia de este hallazgo histopatológico es su asociación con neoplasias malignas de origen endometrial y cervical, por lo cual el patólogo debe realizar un correcto abordaje morfológico e inmunohistoquímico. Se presenta un caso de endometritis xantogranulomatosa asociado a carcinoma escamocelular mal diferenciado de cérvix.Caso Clínico: paciente femenina de 75 años de edad, con
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9

Pérez-Montiel, Camilo Andrés. "Nueva clasificación molecular del carcinoma de endometrio: impacto en el diagnóstico histopatológico, tratamiento y pronóstico." MedUNAB 24, no. 3 (2022): 365–74. http://dx.doi.org/10.29375/01237047.4015.

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Introducción. El carcinoma de endometrio es una patología heterogénea a nivel patogénico, histopatológico y molecular. En los últimos años se han sumado esfuerzos para esclarecer y aumentar el conocimiento de las bases moleculares, logrando así dividir las pacientes en cuatro subgrupos descritos por el Atlas del Genoma del Cáncer (TCGA, por sus siglas en inglés), obteniéndose valiosa información que afecta el diagnóstico, tratamiento y pronóstico de las pacientes con esta enfermedad. El objetivo de la siguiente revisión es exponer la nueva clasificación molecular del carcinoma de endometrio, a
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10

Ferrero, S., C. Esteve, I. Mora, J. Sabrià, E. González, and J. M. Lailla. "Carcinoma de endometrio y ovario sincrónicos." Clínica e Investigación en Ginecología y Obstetricia 34, no. 2 (2007): 77–79. http://dx.doi.org/10.1016/s0210-573x(07)74478-7.

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11

Soihet, Samoel. "Estrogenoterapia Prolongada en Postmenopausicas y Carcinoma de Endometrio: 20 Años de Seguimiento." Revista Peruana de Ginecología y Obstetricia 28, no. 1 y 2 (2015): 33–39. http://dx.doi.org/10.31403/rpgo.v28i664.

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Con el fin de mejorar los síntomas climatéricos, desde 1960 se comenzó a administrar de 6 -7.5 mg diarios de estrógenos, con la consecuente hemorragia. Algunos legrados mostraron hiperplasia endometrial quística. Luego, se realizaron estudios del endometrio, previos al tratamiento de las candidatas. Durante 20 años fueron seleccionadas 2814 mujeres. Fueron separadas del estudio aquellas con patología cervical, endometrial o mamaria; se les administró estradiol sintético y/o estrógenos conjugados: 0,265-1,25 mg en forma interdiaria. A pesar de los estudios clínicos y epidemiológicos retrospecti
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12

Serteva, D., E. Poryazova, and Ts Velikova. "Endometriosis Locations and Coexistence with other Uterine Conditions in a Bulgarian Sample of Patients." American International Journal of Multidisciplinary Scientific Research 5, no. 2 (2019): 5–9. http://dx.doi.org/10.46281/aijmsr.v5i2.255.

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Endometriosis is a non-tumor, estrogen-dependent, chronic gynecological disease, which is characterized by the presence of endometrial glands and stroma outside the endometrium of the uterus. Endometriosis affects between 10% and 15% of women in reproductive age. It is often associated with chronic pelvic pain and reproductive difficulties. Endometriosis can be classified as ovarian, extra-ovarian or mixed. Adenomyosis is considered, by some authors, as a separate variant of endometriosis. It is diagnosed as the presence of ectopic benign endometrial glands and stroma in the myometrium, where
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13

Elhafey, Ahmed S., John C. Papadimitriou, Mohamed S. El-Hakim, Ahmed I. El-Said, Bahaa B. Ghannam, and Steven G. Silverberg. "Computerized Image Analysis of p53 and Proliferating Cell Nuclear Antigen Expression in Benign, Hyperplastic, and Malignant Endometrium." Archives of Pathology & Laboratory Medicine 125, no. 7 (2001): 872–79. http://dx.doi.org/10.5858/2001-125-0872-ciaopa.

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Abstract Context.—The endometrium is an intrinsically dynamic tissue with great capability for regeneration and proliferation; consequently, there is some overlap between features seen in benign, premalignant, and malignant lesions. This leads to marked intrabiopsy, interbiopsy, and interobserver variability. Objective.—We studied the specificity and sensitivity of computerized image analysis of molecular markers to evaluate its potential use as a diagnostic tool. Design.—Specimens from 100 patients were examined and the following histologic diagnoses were assigned: proliferative endometrium (
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14

Lara, Ernesto. "Neoplasia intraepitelial endometrial: una lesión precursora de cáncer de endometrio." Revista de Obstetricia y Ginecología de Venezuela 81, no. 01 (2021): 75–85. http://dx.doi.org/10.51288/00810111.

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Endometrial cancer represents worldwide the sixth most common malignant pathology in the female population, the endometroid type constitutes the most common form, usually developed from a typical sequence of endometrial hyperplasia secondary to sustained exposure to unopposed estrogens balanced by progestogens. Different classification systems for endometrial hyperplasia have been described, the most recent, published by the World Health Organization in 2014, proposes two categories: 1) hyperplasia without atypia, and 2) atypical hyperplasia or endometrial intraepithelial neoplasia. This class
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15

Quddus, M. Ruhul, Predrag Latkovich, William J. Castellani, et al. "Expression of Cyclin D1 in Normal, Metaplastic, Hyperplastic Endometrium and Endometrioid Carcinoma Suggests a Role in Endometrial Carcinogenesis." Archives of Pathology & Laboratory Medicine 126, no. 4 (2002): 459–63. http://dx.doi.org/10.5858/2002-126-0459-eocdin.

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Abstract Context.—Endometrioid carcinoma is often preceded by characteristic histopathologic lesions known as endometrial hyperplasia. Estrogen appears to be involved in the development of endometrioid carcinoma. Other mechanisms of endometrial carcinogenesis include mutations in p53 and PTEN tumor suppressor genes and overexpression of cyclin D1. However, the pattern of cyclin D1 expression is not well defined in normal, hyperplastic, neoplastic, and metaplastic endometrium. Design.—Cyclin D1 immunohistochemical analysis was used to evaluate 108 fixed, paraffin-embedded endometrial biopsy spe
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16

Laguna Olmos, Mariano, Ana Cristina Ruiz Peña, María José Puente Martínez, et al. "Carcinoma endometrioide sincrónico de ovario y endometrio." Revista chilena de obstetricia y ginecología 85, no. 3 (2020): 263–69. http://dx.doi.org/10.4067/s0717-75262020000300263.

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17

Gallego Noreña, Gildardo, Jaime Uribe Duque, and Juan Luis Londoño. "Carcinoma de endometrio. Quince años de experiencia." Revista Colombiana de Obstetricia y Ginecología 37, no. 4 (1986): 299–307. http://dx.doi.org/10.18597/rcog.1932.

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El Cáncer Endometrial ocupa el tercer lugar en frecuencia entre las neoplasias genitales malignas de la mujer. Las publicaciones a nivel mundial indican un incremento en la frecuencia, en oposición al cáncer cérvico uterino que muestra una franca disminución.
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18

Alcaide, Noelia, Benito Velayos, Guillermo González Redondo, et al. "Fístulas ileocólicas tras radioterapia por carcinoma de endometrio." Gastroenterología y Hepatología 39, no. 1 (2016): 23–24. http://dx.doi.org/10.1016/j.gastrohep.2014.12.009.

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19

Arai, Y., and M. Nishida. "Differential diagnosis between normal endometrium and endometrial hyperplasia with immunostaining cytology using anti-LeY monoclonal antibody." International Journal of Gynecologic Cancer 13, no. 1 (2003): 42–46. http://dx.doi.org/10.1136/ijgc-00009577-200301000-00008.

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We have previously reported that both endometrial cancer and endometrial hyperplasia stain positively for the anti-LeY monoclonal antibody, whereas normal endometrium does not. Endometrial hyperplasia is a premalignant change associated with the eventual development of endometrial carcinoma. However, it can be difficult to differentiate hyperplasia from normal endometrium in cytology. This study illustrates the use of immunocytochemical cytology using anti-LeY monoclonal antibody to differentiate between endometrial hyperplasia and normal endometrium. Immunostaining using anti-LeY monoclonal a
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20

Bedoya Hevia, Mariano. "Lesiones pre-malignas del endometrio." Revista Peruana de Ginecología y Obstetricia 18, no. 1-2-3 (2015): 225–27. http://dx.doi.org/10.31403/rpgo.v18i1488.

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La hiperplasia genuina, macroscópicamente puede confundirse con el cáncer; pero se le distingue porque el último presenta necrosis y friabilidad. La hiperplasia adenomatosa puede confundirse con el cáncer; en opinión de varios autores (Gundberg, Kaplan), los cambios atípicos están relacionados con una prolongada estimulación estrogénica. Novack reconoce la existencia de cierta correlación entre hiperplasia post-menopáusica y adenocarcinoma. Wilson y Beecham y Carrington, expresan que la hiperplasia adenomatosa exhibe evidencias suficientes para ser consideradas como lesiones pre cancerosas o c
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21

Okuda, Tsuyoshi, Akihiko Sekizawa, Yuditiya Purwosunu, et al. "Genetics of Endometrial Cancers." Obstetrics and Gynecology International 2010 (2010): 1–8. http://dx.doi.org/10.1155/2010/984013.

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Endometrial cancers exhibit a different mechanism of tumorigenesis and progression depending on histopathological and clinical types. The most frequently altered gene in estrogen-dependent endometrioid endometrial carcinoma tumors isPTEN. Microsatellite instability is another important genetic event in this type of tumor. In contrast,p53mutations or Her2/neu overexpression are more frequent in non-endometrioid tumors. On the other hand, it is possible that the clear cell type may arise from a unique pathway which appears similar to the ovarian clear cell carcinoma.K-rasmutations are detected i
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22

Sangwan, Karuna, Monika Garg, Nayana Pathak, and Lavleen Bharti. "Expression of Cyclin D1 in Hyperplasia and Carcinoma of Endometrium and Its Correlation with Histologic Grade, Tumor Type, and Clinicopathological Features." Journal of Laboratory Physicians 12, no. 03 (2020): 165–70. http://dx.doi.org/10.1055/s-0040-1721150.

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Abstract Background Endometrial carcinoma is often preceded by characteristic histopathologic lesions known as endometrial hyperplasia. Estrogen, p53, PTEN, and overexpression of cyclin D1 appear to be involved in the development of endometrial carcinogenesis. Design We evaluated and compared the expression profile of cyclin D1 expressions in 50 endometrial samples submitted as either endometrial curetting (n = 34) or hysterectomy (n = 16) specimens, which were diagnosed as simple hyperplasia (n = 10), complex hyperplasia (n = 06), atypical hyperplasia (n = 04), and endometrial carcinoma (n =
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23

Álvarez, Guillermo, Pedro Salazar, and Silvio Alvarado. "Sonohisterografía en el estudio de la infertilidad." Revista Peruana de Ginecología y Obstetricia 42, no. 3 (2015): 23–26. http://dx.doi.org/10.31403/rpgo.v42i1800.

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OBJETIVO: La sonohisterografía en el estudio de la infertilidad. MATERIAL: Quince pacientes infértiles estudiadas con histerosalpingografía y sonohisterografía. MÉTODO: Relleno de la cavidad uterina con solución salina estéril, a través de un catéter y bajo control sonográfico, RESULTADOS: La sonohisterografía nos permite una mejor diferenciación de las capas entre el endometrio y miometrio durante el ciclo menstrual. En alteraciones uterinas, visualiza lesiones intracavitarias con mayor precisión que la endosonografía habitual; pólipos y sinequias endometriales, miomas submucosos o carcinoma
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Amalinei, Cornelia, Raluca Balan, Luminita Ivan, Razvan Socolov, Demetra Socolov, and Coriolan Cotutiu. "Multiple primary malignant neoplasms — case report." Open Medicine 1, no. 1 (2006): 87–98. http://dx.doi.org/10.2478/s11536-006-0004-0.

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AbstractThe synchronous occurence of primary carcinomas of endometrium and ovary is well recognized. Malignant peripheral nerve sheath tumours (MPNSTs) may also rarely occur in patients diagnosed with malignancies of the female genital tract. We report a rare case of synchronous primary carcinomas of endometrium and ovary, followed by a metachronous retroperitoneal MPNST. Ascites cytology and endometrial biopsy, followed by hysterectomy and bilateral adnexectomy, were performed to remove the synchronous tumors. Histology was suggestive of synchronous endometrial endometrioid carcinoma and ovar
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25

Abu-Rustum, Nadeem, Catheryn Yashar, Rebecca Arend, et al. "Uterine Neoplasms, Version 1.2023, NCCN Clinical Practice Guidelines in Oncology." Journal of the National Comprehensive Cancer Network 21, no. 2 (2023): 181–209. http://dx.doi.org/10.6004/jnccn.2023.0006.

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Adenocarcinoma of the endometrium (also known as endometrial cancer, or more broadly as uterine cancer or carcinoma of the uterine corpus) is the most common malignancy of the female genital tract in the United States. It is estimated that 65,950 new uterine cancer cases will have occurred in 2022, with 12,550 deaths resulting from the disease. Endometrial carcinoma includes pure endometrioid cancer and carcinomas with high-risk endometrial histology (including uterine serous carcinoma, clear cell carcinoma, carcinosarcoma [also known as malignant mixed Müllerian tumor], and undifferentiated/d
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SAVCI, Gamze, and Kadir BAKAY. "A rare case of synchronous genital carcinoma involving endometrium and unilateral fallopian tube in a 24 years old patient." Journal of Experimental and Clinical Medicine 39, no. 1 (2022): 308–9. http://dx.doi.org/10.52142/omujecm.39.1.62.

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Multifocal synchronous development of malignancies of the female genital tract is a rare occurrence and less than 3% of primary malignancies of this region is synchronous. Although the simultaneous presentation of endometrial and ovarian carcinoma of the endometrioid type is well described little is known about a similar phenomenon involving the endometrium and fallopian tube. The relationship between the synchronous tumours is uncertain. More illuminating studies are being conducted on the relationship between synchronized endometrial and ovarian carcinomas in recent studies.This case is abou
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27

Lahori, M., and N. Borazan. "Concurrently Presenting Endometrial And Ovarian Endometrioid Adenocarcinomas- A Clinicopathologic Study Of 52 Cases." American Journal of Clinical Pathology 154, Supplement_1 (2020): S48. http://dx.doi.org/10.1093/ajcp/aqaa161.102.

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Abstract Introduction/Objective Concurrent presentation of endometrioid adenocarcinomas in endometrium and ovary is uncommon, but oft-noted. They may arise from ovarian metastasis of endometrial carcinoma, endometrial metastasis of ovarian carcinoma, or synchronous development of independent primary lesions. Scully and Young criteria have been widely used to differentiate the site of origin.1 Role of a field effect in the genesis of synchronous carcinomas is supported by increasing evidence that endometrioid ovarian carcinomas arise from endometriosis. 2–5 Methods All cases of concurrent endom
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Munakata, Satoru, Hanae Kushibiki, Taishi Akimoto, Tsuyoshi Yamashita, and Norihiko Shimoyama. "A Case of Endometrial Carcinosarcoma Containing Sertoliform Endometrioid Carcinoma Component." Case Reports in Pathology 2021 (September 20, 2021): 1–9. http://dx.doi.org/10.1155/2021/5868818.

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Carcinosarcomas (CSs) of the endometrium have admixture of malignant epithelial and mesenchymal components. The carcinomatous component exhibit endometrioid, serous, or clear cell differentiation, or are undifferentiated. CSs are considered homologous or heterologous according to the type of sarcomatous component. Sertoliform endometrioid carcinomas (SECs) of the endometrium which comprise a rare subtype of endometrial cancer, typically occur in the ovary. SECs as a carcinomatous component of CS of the endometrium have not been reported. Here, we report an endometrial carcinosarcoma that conta
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Horrée, Nicole, Paul J. van Diest, Petra van der Groep, Daisy M. D. S. Sie-Go, and A. Peter M. Heintz. "Hypoxia and Angiogenesis in Endometrioid Endometrial Carcinogenesis." Analytical Cellular Pathology 29, no. 3 (2007): 219–27. http://dx.doi.org/10.1155/2007/434731.

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Background: Hypoxia-inducible factor 1α (HIF-1α) plays an essential role in the adaptive response of cells to hypoxia, triggering biologic events associated with aggressive tumor behavior. Methods: Expression of HIF-1α and proteins in the HIF-1α pathway (Glut-1, CAIX, VEGF) in paraffin-embedded specimens of normal (n = 17), premalignant (n = 17) and endometrioid endometrial carcinoma (n = 39) was explored by immunohistochemistry, in relation to microvessel density (MVD). Results: HIF-1α overexpression was absent in inactive endometrium but present in hyperplasia (61%) and carcinoma (87%), with
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Posligua, Lorena, Anais Malpica, Jinsong Liu, Jubilee Brown, and Michael T. Deavers. "Combined Large Cell Neuroendocrine Carcinoma and Papillary Serous Carcinoma of the Endometrium With Pagetoid Spread." Archives of Pathology & Laboratory Medicine 132, no. 11 (2008): 1821–24. http://dx.doi.org/10.5858/132.11.1821.

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Abstract Neuroendocrine carcinomas of the endometrium are rare tumors that can be pure, combined with endometrioid adenocarcinoma, or a component of malignant mixed müllerian tumor. Recently, a case of combined small cell carcinoma and papillary serous carcinoma of the endometrium was described for the first time. We report the first case, to our knowledge, of combined large cell neuroendocrine carcinoma and papillary serous carcinoma of the endometrium, with an unusual pagetoid spread of the neuroendocrine component into normal endometrial and endocervical glands. The endometrial carcinoma ha
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Guzmán G, Pablo, and María José Iriarte C. "Carcinoma epidermoide de cuello uterino con extensión superficial a endometrio." Revista chilena de obstetricia y ginecología 81, no. 2 (2016): 122–25. http://dx.doi.org/10.4067/s0717-75262016000200007.

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32

Reyna-Villasmil, E., D. Torres-Cepeda, M. Colmenares-Vega, O. Delgado-Delgado, and I. Sabatini-Saéz. "Carcinoma neuroendocrino de células pequeñas del endometrio. Reporte de caso." Clínica e Investigación en Ginecología y Obstetricia 36, no. 2 (2009): 70–72. http://dx.doi.org/10.1016/j.gine.2007.12.004.

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33

Baquedano, L., P. J. Coronado, M. A. Martínez-Maestre, et al. "Factores de riesgo para carcinoma de endometrio de alto grado." Clínica e Investigación en Ginecología y Obstetricia 45, no. 2 (2018): 64–68. http://dx.doi.org/10.1016/j.gine.2016.07.004.

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34

Henson, Donald Earl, Arnold M. Schwartz, Amy Tilara, Philip M. Grimley, and William F. Anderson. "Population-Based Analysis of Pathologic Data: A New Approach to the Investigation of Uterine Endometrial and Ovarian Endometrioid Carcinomas." Archives of Pathology & Laboratory Medicine 131, no. 9 (2007): 1337–42. http://dx.doi.org/10.5858/2007-131-1337-paopda.

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Abstract Context.—Population-based analysis of the histopathology of endometrioid adenocarcinoma of the endometrium and ovary combined with epidemiologic techniques offer a new approach to exploring the relationship of tumors that share a similar range of morphologic phenotypes. Objective.—To evaluate the contribution of the Surveillance, Epidemiology, and End Results database to our understanding of gynecologic pathology. Specifically, to test and compare whether the etiology/pathogenesis of ovarian endometrioid cancer is as dependent upon the reproductive environment as uterine endometrial c
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Navarro, M., A. J. Muñoz, and R. Martínez de la Ossa. "Carcinoma escamoso in situ de endometrio y vagina asociado a carcinoma microinvasivo de cérvix." Clínica e Investigación en Ginecología y Obstetricia 35, no. 5 (2008): 190–92. http://dx.doi.org/10.1016/s0210-573x(08)73075-2.

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Hachisuga, T., K. Fukuda, M. Uchiyama, N. Matsuo, T. Iwasaka, and H. Sugimori. "Immunohistochemical study of p53 expression in endometrial carcinomas: correlation with markers of proliferating cells and clinicopathologic features." International Journal of Gynecologic Cancer 3, no. 6 (1993): 363–68. http://dx.doi.org/10.1046/j.1525-1438.1993.03060363.x.

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Using anti-p53 (PAb1801 and PAb240), anti-DNA polymerase α and Ki-67 monoclonal antibodies, the expression of p53 was studied in 11 normal endometria, 14 endometrial hyperplasias and 27 endometrial carcinomas and its relationship to the proliferative activity of the tumors was examined. Normal endometria and simple hyperplasias were completely negative for p53. The PAb1801 indices of complex hyperplasias and complex atypical hyperplasias were 2.5±1.8% and 5.0±3.2%, respectively. The PAb1801 indices of grade 1, grade 2 and grade 3 endometrial carcinomas were 10.2±14.2%, 44.4±29/0% and 45.0±32.5
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37

Erkanli, S., F. Kayaselcuk, E. Kuscu, et al. "Expression of survivin, PTEN and p27 in normal, hyperplastic, and carcinomatous endometrium." International Journal of Gynecologic Cancer 16, no. 3 (2006): 1412–18. http://dx.doi.org/10.1136/ijgc-00009577-200605000-00071.

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We aimed to investigate if expressions of survivin and p27 proteins are involved in the development of endometrioid carcinoma, along with whether there are any correlations between these proteins and loss of wild-type PTEN that is found in up to 80% of endometrial carcinomas. We also studied their correlations with classical prognostic factors and survival in endometrial carcinoma. To our knowledge, this is the first time survivin expression is investigated in endometrial hyperplasia along with endometrioid adenocarcinoma. For immunohistochemical analysis, 29 endometrioid adenocarcinoma, 38 en
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Han, Jiheun, and Hyun-Soo Kim. "Abdominopelvic Metastasis of Endometrial Serous Carcinoma Initially Misdiagnosed as Early-Stage Low-Grade Endometrioid Carcinoma: The Importance of Recognizing Minimal Uterine Serous Carcinoma." Case Reports in Oncology 13, no. 3 (2020): 1537–44. http://dx.doi.org/10.1159/000511701.

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Minimal uterine serous carcinomas (MUSCs) include serous carcinomas with invasion confined to the endometrium (superficial serous carcinoma) and those without stromal invasion (serous endometrial intraepithelial carcinoma). Although these tumors are confined to the endometrium proper, they have highly metastatic potential for disseminating to extra-uterine sites. We report here a case of MUSC that was initially misdiagnosed as early-stage low-grade endometrioid carcinoma but later metastasized to the abdominopelvic peritoneum. The patient was a 61-year-old woman who was diagnosed with grade 1
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Zhan, Xiangbo, Lei Li, Ming Wu, and Jinghe Lang. "The prognosis of stage IA synchronous endometrial endometrioid and ovarian carcinomas." Archives of Gynecology and Obstetrics 300, no. 4 (2019): 1045–52. http://dx.doi.org/10.1007/s00404-019-05288-5.

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Abstract Introduction Little is known about the prevalence and prognosis of synchronous endometrial and ovarian carcinomas. This report explores the survival outcomes of synchronous stage IA endometrioid endometrial and stage IA ovarian carcinomas in a retrospective cohort study. Methods All cases of pathological confirmed synchronous stage IA endometrial endometrioid and ovarian carcinomas from June 1, 2010, to June 1, 2017, in a teaching hospital were reviewed. Patients were followed up to February 1, 2019. Survival outcomes were compared between patients with and without synchronous carcino
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Cruz Tovar, Diana, and Sandra Liliana Garzón. "Citología endometrial de toma directa. Estudio comparativo." Revista Repertorio de Medicina y Cirugía 12, no. 1 (2003): 25–26. http://dx.doi.org/10.31260/repertmedcir.v12.n1.2003.307.

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El carcinoma endometrial se ha convertido en la lesión maligna más frecuente del cuerpo uterino. Se presentan anualmente 34.000 nuevos casos, de los cuales 6.000 ocasionan defunciones, lo que lo convierte en la séptima causa de muerte en mujeres; es más agresivo con el aumento de la edad. Es así como surge la idea de realizar un estudio cuidadoso con la citología endometrial de toma directa, que permita investigar y diagnosticar lesiones hormonales, premalignas y malignas del endometrio, y promueva la citología endometrial de toma directa como un método de tamización para usar con mayor frecue
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Baquedano Mainar, Laura, Pilar Del Tiempo Marqués, Ignacio Adiego Calvo, et al. "Acetato de ulipristal en el diagnóstico diferencial de carcinoma de endometrio." Revista chilena de obstetricia y ginecología 81, no. 2 (2016): 113–16. http://dx.doi.org/10.4067/s0717-75262016000200005.

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Fernández, Esther, M. Carmen Barrera, Cristina Gervás, Emma Salvador, Melcior Sentís, and Borja Rivero. "Carcinoma de endometrio: valor de la estadificación prequirúrgica por resonancia magnética." Radiología 45, no. 3 (2003): 115–23. http://dx.doi.org/10.1016/s0033-8338(03)77873-4.

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43

Salibay, Christine, and Oluwole Fadare. "High-Grade Endometrioid Carcinoma of the Endometrium With a GATA-3-Positive/PAX8-Negative Immunophenotype Metastatic to the Breast: A Potential Diagnostic Pitfall." International Journal of Surgical Pathology 28, no. 6 (2020): 631–36. http://dx.doi.org/10.1177/1066896920913114.

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This report describes clinicopathologic findings from the case of a patient with a breast mass that was ultimately diagnosed as a metastatic high-grade endometrioid carcinoma of endometrial origin. The breast lesion as well as the solid areas of the endometrial lesion displayed a similar immunoprofile: GATA3-positive; synaptophysin positive; negative for mammaglobin, gross cystic disease fluid protein-15, chromogranin, estrogen receptor, progesterone receptor, and HER2/neu; and intact expression of the DNA mismatch repair proteins MLH1, MSH2, MSH6, and PMS2. The breast lesion was negative for
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Perez-Medina, T., V. Engels, F. Salazar, et al. "Anatomopathologic Subtypes of Endometrial Carcinoma: Case-Control Study of 122 Cases. Epidemiology and Ultrasound." Clinical medicine. Oncology 1 (January 2007): CMO.S367. http://dx.doi.org/10.4137/cmo.s367.

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Objective To determine the epidemiological and sonographic characteristics of patients with endometrial carcinoma of endometrioid and non-endometrioid subtype to analyse if any differences can be observed between the groups. Study design A case-control study was performed considering 122 patients with endometrial carcinoma where 96 (78.69%) had endometrioid carcinomas (controls) and 26 (21.31%) had non-endometrioid carcinomas (cases). Epidemiological, clinical, and sonographic variables (endometrial thickness and sonographic suspicion of myometrial invasion of the tumour) were analysed. Qualit
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Rodríguez, Alba, Jara Gallardo, Zoraida Frías, et al. "Tumor sincrónico de endometrio y ovario. Patología infrecuente en ginecología oncológica." Revista de Obstetricia y Ginecología de Venezuela 80, no. 04 (2020): 348–55. http://dx.doi.org/10.51288/00800412.

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Endometrial cancer remains the most common gynecological tumor in women in the United States of America. The simultaneous finding of endometrial and ovarian neoplasm, as a synchronous tumor, accounts for about 5 - 10 % of endometrial and ovarian tumors. Therefore, is a rare entity. Consideration as restricted metastases or pseudometastasis to define the spread of this kind of tumor, is becoming more relevant nowadays thanks to the latest advances in the field of immunohistochemistry and molecular biology. In this article we present the case of a 57-year-old patient initially diagnosed with FIG
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López Fernández, J. A., L. Luque Martínez, M. T. Casanova Sanchís, E. M. Moreno Ruiz, J. C. Martínez Escoriza, and F. M. Peiró-Marqués. "Diagnóstico precoz de carcinoma de endometrio en una paciente tratada con tamoxifeno." Progresos de Obstetricia y Ginecología 45, no. 10 (2002): 448–52. http://dx.doi.org/10.1016/s0304-5013(02)75819-6.

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47

Silverberg, Steven G. "The Endometrium." Archives of Pathology & Laboratory Medicine 131, no. 3 (2007): 372–82. http://dx.doi.org/10.5858/2007-131-372-te.

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Abstract Context.—Endometrial tissue specimens are commonly encountered in daily practice. It is well known that a number of problematic diagnostic scenarios occur relative to these specimens. Objective.—To emphasize practical aspects of endometrial specimen handling and reporting, with selected comments on common diagnostic pitfalls, including (1) the diagnosis of endometrial intraepithelial carcinoma in atrophic endometrial biopsy specimens, (2) evaluation of adequacy of endometrial sampling specimens, (3) problems in diagnosing and measuring the depth of myometrial invasion in endometrial c
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48

Nishimura, N., T. Hachisuga, T. Saito, and T. Kawarabayashi. "Subsequent endometrial carcinoma with adjuvant tamoxifen treatment in Japanese breast cancer patients." International Journal of Gynecologic Cancer 11, no. 4 (2001): 272–76. http://dx.doi.org/10.1136/ijgc-00009577-200107000-00003.

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Abstract.Nishimura N, Hachisuga T, Saito T, Kawarabayashi T. Subsequent endometrial carcinoma with adjuvant tamoxifen treatment in Japanese breast cancer patients.This study aimed to detail the clinicopathologic features of endometrial carcinomas that developed in Japanese patients receiving adjuvant tamoxifen treatment for breast cancer patients. Ten endometrial carcinomas in tamoxifen-treated breast cancer patients were collected from two medical centers. The endometrial carcinomas included two stage Ia, four stage Ib, two stage Ic and two stage IIIc. Three tumors were Grade 1, six were Grad
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Opric, Dejan, Amer Suskic, Sanela Halilovic Suskic, Gorana Nikolic, and Isidora Filipovic. "Value of p53 and estrogen receptors immunohistochemical staining in endometrial carcinoma." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 8, no. 12 (2019): 4885. http://dx.doi.org/10.18203/2320-1770.ijrcog20195339.

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Background: Since there are many articles dealing with estimating prognostic and diagnostic value of ER and p53, using different, usually complex ICH interpretation methods, we wanted to evaluate significance of p53 and ER ICH positivity in endometrial carcinoma, using easily applicable criteria that would help pathologists and clinicians to be sure in ICH findings noted in the report.Methods: This paper deals with data of the patients treated for endometrial carcinoma in Public Hospitals in Travnik, gynecological department in the period from 1st January 2013 to 1st January 2019. The study in
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Bell, Daphne W., and Lora Hedrick Ellenson. "Molecular Genetics of Endometrial Carcinoma." Annual Review of Pathology: Mechanisms of Disease 14, no. 1 (2019): 339–67. http://dx.doi.org/10.1146/annurev-pathol-020117-043609.

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Endometrial cancer is the most commonly diagnosed gynecologic malignancy in the United States. Endometrioid endometrial carcinomas constitute approximately 85% of newly diagnosed cases; serous carcinomas represent approximately 3–10% of diagnoses; clear cell carcinoma accounts for <5% of diagnoses; and uterine carcinosarcomas are rare, biphasic tumors. Longstanding molecular observations implicate PTEN inactivation as a major driver of endometrioid carcinomas; TP53 inactivation as a major driver of most serous carcinomas, some high-grade endometrioid carcinomas, and many uterine carcinosarc
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