Relevant bibliographies by topics / Carbocyclic compounds

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  2. Dissertations / Theses
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Academic literature on the topic 'Carbocyclic compounds'

Author: Grafiati
Published: 7 September 2023
Last updated: 18 May 2024

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Journal articles on the topic "Carbocyclic compounds"

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Murarka, Sandip, and Andrey Antonchick. "Metal-Catalyzed Oxidative Coupling of Ketones and Ketone Enolates." Synthesis 50, no. 11 (May 3, 2018): 2150–62. http://dx.doi.org/10.1055/s-0037-1609715.

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Recent years have witnessed a significant advancement in the field of radical oxidative coupling of ketones towards the synthesis of highly useful synthetic building blocks, such as 1,4-dicarbonyl compounds, and biologically important heterocyclic and carbocyclic compounds. Besides oxidative homo- and cross-coupling of enolates, other powerful methods involving direct C(sp3)–H functionalizations of ketones­ have emerged towards the synthesis of 1,4-dicarbonyl compounds. Moreover, direct α-C–H functionalization of ketones has also allowed an efficient access to carbocycles and heterocycles. This review summarizes all these developments made since 2008 in the field of metal-catalyzed/promoted radical-mediated functionalization of ketones at the α-position.1 Introduction2 Synthesis of 1,4-Dicarbonyl Compounds3 Synthesis of Heterocyclic Scaffolds4 Synthesis of Carbocyclic Scaffolds5 Conclusion
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Sidi Mohamed, Bemba, Christian Périgaud, and Christophe Mathé. "Revaluation of biomass-derived furfuryl alcohol derivatives for the synthesis of carbocyclic nucleoside phosphonate analogues." Beilstein Journal of Organic Chemistry 13 (February 9, 2017): 251–56. http://dx.doi.org/10.3762/bjoc.13.28.

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The racemic synthesis of new carbocyclic nucleoside methylphosphonate analogues bearing purine bases (adenine and guanine) was accomplished using bio-sourced furfuryl alcohol derivatives. All compounds were prepared using a Mitsunobu coupling between the heterocyclic base and an appropriate carbocyclic precursor. After deprotection, the compounds were evaluated for their activity against a large number of viruses. However, none of them showed significant antiviral activity or cytotoxicity.
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Biteau, Nicolas G., Sarah A. Amichai, Niloufar Azadi, Ramyani De, Jessica Downs-Bowen, Julia C. Lecher, Tamara MacBrayer, Raymond F. Schinazi, and Franck Amblard. "Synthesis of 4′-Substituted Carbocyclic Uracil Derivatives and Their Monophosphate Prodrugs as Potential Antiviral Agents." Viruses 15, no. 2 (February 16, 2023): 544. http://dx.doi.org/10.3390/v15020544.

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Over the past decades, both 4′-modified nucleoside and carbocyclic nucleoside analogs have been under the spotlight as several compounds from either family showed anti-HIV, HCV, RSV or SARS-CoV-2 activity. Herein, we designed compounds combining these two features and report the synthesis of a series of novel 4′-substituted carbocyclic uracil derivatives along with their corresponding monophosphate prodrugs. These compounds were successfully prepared in 19 to 22 steps from the commercially available (-)-Vince lactam and were evaluated against a panel of RNA viruses including SARS-CoV-2, influenza A/B viruses and norovirus.
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Ando, Wataru. "Polyorganosilicon Compounds in Strained Carbocyclic Systems." Bulletin of the Chemical Society of Japan 69, no. 1 (January 1996): 1–16. http://dx.doi.org/10.1246/bcsj.69.1.

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Yavari, Issa, and Aliyeh Khajeh-Khezri. "Recent Advances in the Synthesis of Hetero- and Carbocyclic Compounds­ and Complexes Based on Acenaphthylene-1,2-dione." Synthesis 50, no. 20 (August 16, 2018): 3947–73. http://dx.doi.org/10.1055/s-0037-1610209.

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Acenaphthylene-1,2-dione has been utilized in a wide range of reactions as a starting material for the synthesis of hetero- and carbocyclic compounds and complexes. This review provides a short summary of the recent advances in the application of acenaphthylene-1,2-dione in the synthesis of hetero- and carbocyclic systems and bioactive compounds. In addition, the applications of acenaphthylene-1,2-dione in the synthesis of spiro compounds, propellanes, and ligands in catalyst reactions, from 2002 to early 2018, are included.1 Introduction2 Synthesis of Spiro Compounds Employing Acenaphthylene-1,2-dione2.1 Methods for the Construction of Spiro Compounds2.1.1 By 1,3-Dipolar Cycloaddition of Acenaphthylene-1,2-dione via Azomethine Ylides2.1.2 By Multicomponent Reactions of Acenaphthylene-1,2-dione with C–H Acidic Compounds2.1.3 By Reaction of Acenaphthylene-1,2-dione with Zwitterionic Intermediates2.1.4 By Substitution and Multicomponent Reactions of Acenaphth- ylene-1,2-dione with Different Nucleophiles3 Synthesis of Propellanes by Employing Acenaphthylene-1,2-dione3.1 Methods for the Construction of Propellanes Based on Acenaph- thylene-1,2-dione3.1.1 By Reaction of Acenaphthylene-1,2-dione with Nucleophiles3.1.2 By Reaction of Acenaphthylene-1,2-dione with Binucleophiles4 Synthesis of Ligands Employing Acenaphthylene-1,2-dione for Catalyst Reactions5 Synthesis of Novel Hetero- and Carbocyclic Compounds Employing Acenaphthylene-1,2-dione5.1 By Reaction of Acenaphthylene-1,2-dione with Nucleophiles5.2 By Reaction of Acenaphthylene-1,2-dione with Zwitterionic Intermediates5.3 By Ring Opening and Ring Enlargement6 Conclusion
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Gaber, Hatem M., Mark C. Bagley, Zeinab A. Muhammad, and Sobhi M. Gomha. "Recent developments in chemical reactivity of N,N-dimethylenamino ketones as synthons for various heterocycles." RSC Advances 7, no. 24 (2017): 14562–610. http://dx.doi.org/10.1039/c7ra00683g.

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Halimehjani, Azim Ziyaei, Irishi N. N. Namboothiri, and Seyyed Emad Hooshmand. "Nitroalkenes in the synthesis of carbocyclic compounds." RSC Advances 4, no. 59 (June 24, 2014): 31261. http://dx.doi.org/10.1039/c4ra04069d.

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Bartulewic, D., A. Markowska, S. Wołczyński, M. Dabrowska, and A. Rózański. "Molecular modelling, synthesis and antitumour activity of carbocyclic analogues of netropsin and distamycin--new carriers of alkylating elements." Acta Biochimica Polonica 47, no. 1 (March 31, 2000): 23–35. http://dx.doi.org/10.18388/abp.2000_4059.

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A series of netropsin and distamycin analogues was synthesised and investigated by molecular modelling. The lowest-energy conformations of four carbocyclic lexitropsins, potential carriers of alkylating elements, were obtained using the HyperChem 4.0 program, and compared with the DNA-lexitropsin crystal structures from the Brookhaven National Laboratory Protein Data Bank. A method for synthesis of carbocyclic lexitropsins was elaborated, with the use of a nitro group or azobenzene as precursors for the aromatic amino group. The influence of methoxy group in ortho position with respect to amide groups on the activity of the new compounds was investigated. All of the compounds tested showed high antitumour activity in the standard cell line of mammalian tumour MCF-7.
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Niu, Ben, Yin Wei, and Min Shi. "Recent advances in annulation reactions based on zwitterionic π-allyl palladium and propargyl palladium complexes." Organic Chemistry Frontiers 8, no. 13 (2021): 3475–501. http://dx.doi.org/10.1039/d1qo00273b.

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Carbocyclic and heterocyclic compounds could be constructed through the palladium-catalyzed annulation reactions of zwitterionic π-allyl palladium or propargyl palladium complexes with unsaturated electrophiles.
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Liu, Yuxiao, Yu Liu, Charles S. Shanahan, Xichen Xu, and Michael P. Doyle. "A survey of enoldiazo nucleophilicity in selective C–C bond forming reactions for the synthesis of natural product-like frameworks." Org. Biomol. Chem. 12, no. 28 (2014): 5227–34. http://dx.doi.org/10.1039/c4ob00709c.

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Dissertations / Theses on the topic "Carbocyclic compounds"

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Phun, Lien Hoang. "Innovative approaches to carbocyclic and heterocyclic compounds using strained carbocycles." Diss., Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/47542.

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Natural products and small molecules play a major role in drug development. However, using natural products as a source of medicine comes with many challenges, such as lack of natural abundance and difficulty in isolation. Consequently, synthetic organic chemistry is a solution in order to access these compounds in usable quantities. However, synthetic chemisty comes with its own challenges such as efficiency, chemoselectivity, stereoselectivity and enantioselectivity. Therefore, synthetic tools that addresses these challenges are required solve these limitations. This thesis discusses new methodologies using strained carbocycles (cyclopropanes and cyclopropenes) as the reactive subunit for the construction of different carbocyclic and heterocyclic compounds. The homo-Nazarov cyclization of alkenyl and heteroaryl cyclopropyl ketones was used in order to construct cyclohexenones, cyclohexenols, heteroaryl ring-fused cyclohexenones, dihydrofurans, furans and furanones in a mild and efficient manner. Benzofused heteroaromatic compounds were achieved via the Lewis acid-catalyzed cycloisomerization of cyclopropene-3,3-dicarbonyls and furan-3-carboxylates. These heteroaromatic compounds can be applied to medicinal chemistry and material science.
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Das, Jayanta. "Trans formative reactions on carbocyclic compounds." Thesis, University of North Bengal, 2015. http://ir.nbu.ac.in/handle/123456789/1863.

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Ghosh, Pranab. "Studies on chemical reactions of carbocyclic compounds." Thesis, University of North Bengal, 1991. http://hdl.handle.net/123456789/767.

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Bright, Steven. "Acid induced cationic rearrangements of carbocyclic compounds." Thesis, University of Canterbury. Chemistry, 1988. http://hdl.handle.net/10092/7597.

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This thesis examines fluorosulfonic acid as a reagent for use in organic synthesis. The acid strength of fluorosulfonic acid gives access to rearrangement products not available with weaker acids. The reaction of a selected series of benzyl carbinols with HSO₃F are reported. Reaction of 1-benzyl-2-methylcyclohexanol (1) gave cis-4a-methyl-1,2,3,4,4a,9a-hexahydrofluorene (2), while 1-benzyl -3-methylcyclohexanol (10) and 1-benzyl-4-methylcyclohexanol (11) were reduced to cis-1-benzyl-3-methylcyclohexane (12) and trans-1-benzyl-4-methylcyclohexane (13) respectively. [Diagram in thesis] 6-Benzylspiro[4.5]decan-6-ol (4) underwent a ring expansion to give the propellane, tetracyclo[7.4.4.0¹⁹.0²⁷]heptadeca-2,4,6-triene (5). Reaction of 1-benzyl-trans-decalin-1-ol (6) with HSO₃F gave the natural product (±)-9a-carba-14α-morphinan (7), while spiro[3-exobenzylbicyclo[2,2,1]heptan-3-endo-ol-2,1'-cyclopentane] (41) gave pentacyclo [9.7.0.0¹,¹⁴.0³,⁸.0⁹,¹⁴]octadeca-3,5,7-triene (42). The mechanism of rearrangement of 2-exo-benzylbicyclo[2.2.1] heptan-2-endo-ol (14) to 6-phenylbicyclo[3.2.1]oct-6-ene (16) was elucidated by the use of deuterium labeled substrates. Reaction of phenylethyl carbinols with HSO₃F afforded a route to bicyclic systems, for example 1-(2-phenylethyl)cyclohexanol (59) gave cis-1,2,3,4,4a,9,10,10a-octahydrophenanthrene (61) and spiro[cyclohexane-1,1-indane] (60), while 2-methyl-1-(2- phenylethyl)cyclohexanol (64) gave a mixture of cis- (65) and trans-4a-methyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene (66). [Diagram in thesis] Reaction of 1-(2-phenylethyl)-2,2,6-trimethylcyclohexanol (70) gave predominantly 1β,4aβ, 10 aβ-trimethyl-1,2,3,4,4a,9,10,10a octahydrophenanthrene (72) with a small amount of the 1a,4aβ,10aβ-trimethyl-isomer (73) while reaction of 2-exo-(2- phenylethyl)bicyclo[2,2,1 ]heptan-2-endo-ol (74) gave tetracyclo[10.2.1.0¹,¹⁰.0⁴,⁹]pentadeca-4,6,8-triene (75). Phenylpropyl carbinols provide an entry to spiro products. Reaction of 1-(3-phenylpropyl)cyclohexanol (85) gave spiro[cyclohexane-1,1-tetralin] (86), while 2-methyl-1-(3- phenylpropyl)cyclohexanol (87) gave trans-2'-methylspiro[ cyclohexane-1,1-tetralin] (88). [Diagram in thesis] 1,4-Diphenylbutan-1-ol (95) afforded 1-phenyl-1,2,3,4- tetrahydronapthalene (96) and 2,5-diphenylpentan-2-ol (97) gave an analogous product (98). 1,4-Di-(1-hydroxy-4-phenylbutan-1-yl)benzene (99) gave the two diastereoisomers of 1,4-di-(1,2,3,4-tetrahydronapth-1-yl)benzene (100), which on oxidation gave 1,4-di-(1-naphthyl) benzene (101). Fluorosulfonic acid has been shown to be a synthetic reagent for the generation of several novel spiro, reduction, cyclisation and rearrangement products not accessible under weaker acid conditions.
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Van, Eeden Nestor. "Synthesis of some potential antimicrobial carbocyclic compounds." Thesis, Cape Technikon, 1994. http://hdl.handle.net/20.500.11838/745.

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Thesis (M. Diploma in Technology (Chemistry))--Cape Technikon, 1994
Some naturally occurring compounds containing the naphtho [2,3 - c] pyran ring system have been found to be useful antibiotic agents and thus the laboratory synthesis ofthese compounds and their derivatives are of importance in the medical field. Their antibiotic and even antineoplastic activities are attributed to their potential to act as alkylating agents, via a bioreductive process. This thesis deals with studies directed towards the synthesis of some benzo [c] pyrans as these compounds also possess the correct structural configuration to undergo the bioreductive process, and act as alkylating agents to cellular nucleic acids. Chapter Two describes the synthesis 00,4 dihydro - 1,3 - dimethyl- IH - benzo - [cl pyran - 5,8 - quinone (13) by employing a base induced cyclization with potassium tertiary butoxide. This compound was proven to be biologically active against both Gram positive and Gram negative organisms. (±) (1R, 3R, 4R) - 3,4 - Dihydro - 4 - hyroxy -1,3 - dimethyl- 1H - benzo [e] pyran - 5,8quinone (17) and its 4 S diastereomer (18) were synthesized with cerium (IV) ammonium nitrate as the cyclizing reagent. Antimicrobial evaluation ofcompound (17) displayed inhibitory activity against both Gram positive and Gram negative organism growth. This is discussed in Chapter Three. In Chapter Four, the synthesis ofthe benzo analogue ofthe naturally occurring naphthopyran antibiotic, hongconin, is discussed. The synthetic route used for this synthesis could well be applied to synthesise hongconin.
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Pradhan, Nagendra Narayan. "Studies on the chemical reactions of carbocyclic compounds." Thesis, University of North Bengal, 2002. http://hdl.handle.net/123456789/743.

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Mothay, jyotsna. "Studies on the transformative reactions of carbocyclic compounds." Thesis, University of North Bengal, 2002. http://hdl.handle.net/123456789/771.

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Singha, Rabindranath. "Chemical transformation of carbocyclic compounds and development of novel reaction protocols." Thesis, University of North Bengal, 2021. http://ir.nbu.ac.in/handle/123456789/4326.

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Dutta, Gopal. "Chemical investigation of naturally occurring carbocyclic ring compounds." Thesis, University of North Bengal, 1989. http://hdl.handle.net/123456789/836.

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Lau, Clifford James. "A study of several interesting carbocyclic molecules /." The Ohio State University, 1987. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487584612166485.

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Books on the topic "Carbocyclic compounds"

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1936-, Ōsawa Eiji, and Yonemitsu Osamu 1930-, eds. Carbocyclic cage compounds: Chemistry and applications. New York, N.Y: VCH, 1992.

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Carbocycle construction in terpene synthesis. New York, N.Y: VCH, 1988.

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The chemistry of conjugated cyclic compounds: To be or not to be like benzene? Chichester: Wiley, 1989.

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E, Osawa, and Yonemitsu O, eds. Carbocyclic Cage Compounds: Chemistry and Applications. VCH Verlagsgesellschaft, Germany, 1992.

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Carbocyclic Three- and Four-membered Ring Compounds. G.Thieme Verlag,Germany, 1996.

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Carbocyclic Three- and Four-membered Ring Compounds. G.Thieme Verlag,Germany, 1997.

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Meijere, Armin De, (Ed.), ed. Carbocyclic Three- and Four-membered Ring Compounds. G.Thieme Verlag,Germany, 1996.

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(Editor), Eiji Osawa, and Osamu Yonemitsu (Editor), eds. Carbocyclic Cage Compounds: Chemistry and Applications (Methods in Stereochemical Analysis). Wiley-VCH, 1992.

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Worakun, Tanachat. Palladium and rhodium catalysed construction of carbocyclic and heterocyclic compounds. 1987.

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Yonemitsu, Osamu. Carbocyclic Cage Compounds: Chemistry and Applications (Methods in Stereochemical Analysis). VCH Publishers, 1992.

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Book chapters on the topic "Carbocyclic compounds"

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Thummel, R. P. "Carbocyclic Annelated Pyridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs, 253–445. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186701.ch2.

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Ninomiya, I., and T. Naito. "Preparation of Carbocyclic Compounds." In Photochemical Synthesis, 51–134. Elsevier, 1989. http://dx.doi.org/10.1016/b978-0-12-519490-7.50012-8.

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"Substituted Carbocyclic Aromatic Compounds." In Environmental Degradation and Transformation of Organic Chemicals, 455–522. CRC Press, 2007. http://dx.doi.org/10.1201/9781420006773.ch9.

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"Carbocyclic Aromatic Compounds without Halogen Substituents." In Organic Chemicals in the Environment, 713–808. CRC Press, 2012. http://dx.doi.org/10.1201/b12492-12.

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"Carbocyclic Aromatic Compounds without Halogen Substituents." In Environmental Degradation and Transformation of Organic Chemicals, 385–454. CRC Press, 2007. http://dx.doi.org/10.1201/9781420006773.ch8.

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Spitzner, D. "Of Three-Membered Carbocyclic or Heterocyclic Compounds." In Six-Membered Hetarenes with One Nitrogen or Phosphorus Atom, 1. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-015-00167.

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Spitzner, D. "Of Five-Membered Carbocyclic or Heterocyclic Compounds." In Six-Membered Hetarenes with One Nitrogen or Phosphorus Atom, 1. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-015-00176.

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"2.1.1. Rearrangement of Homoallylic Compounds." In Carbocyclic Three- and Four-Membered Ring Compounds, edited by Armin de Meijere. Stuttgart: Georg Thieme Verlag, 1997. http://dx.doi.org/10.1055/b-0035-113163.

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"Primary Syntheses from Aliphatic or Carbocyclic Synthons." In Chemistry of Heterocyclic Compounds: A Series Of Monographs, 1–58. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470187975.ch1.

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"3.5. From Cyclopropenes and Metal Carbonyl Compounds." In Carbocyclic Three- and Four-Membered Ring Compounds, edited by Armin de Meijere. Stuttgart: Georg Thieme Verlag, 1997. http://dx.doi.org/10.1055/b-0035-112564.

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