Academic literature on the topic 'Canine oral melanoma'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Canine oral melanoma.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Canine oral melanoma"
Bergman, Philip J. "Canine Oral Melanoma." Clinical Techniques in Small Animal Practice 22, no. 2 (May 2007): 55–60. http://dx.doi.org/10.1053/j.ctsap.2007.03.004.
Full textBehra, Biswadeep, S. Vairamuthu, Natesan Pazhanivel, Periyasamy Jalantha, and Ganne Venkata Sudhakar Rao. "Histological and Immunohistochemical Features of Pulmonary Metastatic Oral Melanoma in a Labrador dog." Indian Journal of Veterinary Sciences & Biotechnology 18, no. 5 (November 7, 2022): 119–22. http://dx.doi.org/10.48165/ijvsbt.18.5.24.
Full textConrad, David, Alexandra Kehl, Christoph Beitzinger, Thomas Metzler, Katja Steiger, Nicole Pfarr, Konrad Fischer, Robert Klopfleisch, and Heike Aupperle-Lellbach. "Molecular Genetic Investigation of Digital Melanoma in Dogs." Veterinary Sciences 9, no. 2 (January 30, 2022): 56. http://dx.doi.org/10.3390/vetsci9020056.
Full textPalma, Stefano Di, Ashleigh McConnell, Sara Verganti, and Mike Starkey. "Review on Canine Oral Melanoma: An Undervalued Authentic Genetic Model of Human Oral Melanoma?" Veterinary Pathology 58, no. 5 (March 9, 2021): 881–89. http://dx.doi.org/10.1177/0300985821996658.
Full textShimoyama, Y., Y. Akihara, D. Kirat, H. Iwano, K. Hirayama, Y. Kagawa, T. Ohmachi, et al. "Expression of Monocarboxylate Transporter 1 in Oral and Ocular Canine Melanocytic Tumors." Veterinary Pathology 44, no. 4 (July 2007): 449–57. http://dx.doi.org/10.1354/vp.44-4-449.
Full textProuteau and André. "Canine Melanomas as Models for Human Melanomas: Clinical, Histological, and Genetic Comparison." Genes 10, no. 7 (June 30, 2019): 501. http://dx.doi.org/10.3390/genes10070501.
Full textDe Andrade, Gisele Braziliano, Alanderson Rodrigues Da Silva, João Bosco Vilela Campos, Joyce Katiuccia Medeiros Ramos Carvalho, Rosalina Marina Infiesta Zulim, Luciano Pereira De Barros, Cristiano Marcelo Espinola Carvalho, and Heitor Miraglia Herreira. "Canine Oral Osteocartilaginous Malignant Amelanotic Melanoma with Pulmonary Metastasis." Acta Scientiae Veterinariae 46 (July 29, 2018): 8. http://dx.doi.org/10.22456/1679-9216.87456.
Full textTellado, Matías Nicolás, Felipe Horacio Maglietti, Sebastián Diego Michinski, Guillermo Ricardo Marshall, and Emanuela Signori. "Electrochemotherapy in treatment of canine oral malignant melanoma and factors influencing treatment outcome." Radiology and Oncology 54, no. 1 (March 7, 2020): 68–78. http://dx.doi.org/10.2478/raon-2020-0014.
Full textAlmela, Ramón, and Agustina Ansón. "A Review of Immunotherapeutic Strategies in Canine Malignant Melanoma." Veterinary Sciences 6, no. 1 (February 12, 2019): 15. http://dx.doi.org/10.3390/vetsci6010015.
Full textZamarian, Valentina, Carlotta Catozzi, Lorenzo Ressel, Riccardo Finotello, Fabrizio Ceciliani, Miguel Vilafranca, Jaume Altimira, and Cristina Lecchi. "MicroRNA Expression in Formalin-Fixed, Paraffin-Embedded Samples of Canine Cutaneous and Oral Melanoma by RT-qPCR." Veterinary Pathology 56, no. 6 (September 16, 2019): 848–55. http://dx.doi.org/10.1177/0300985819868646.
Full textDissertations / Theses on the topic "Canine oral melanoma"
Kmetiuk, Louise Nicolle Bach. "Desenvolvimento e avaliação comparativa do melanoma oral em camundongos, frente sua ocorrência espontânea em cães." Universidade Estadual de Ponta Grossa, 2016. http://tede2.uepg.br/jspui/handle/prefix/2761.
Full textMade available in DSpace on 2019-03-15T11:31:48Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) Louise Nicolle Bach.pdf: 1549158 bytes, checksum: f6d6348279d210b0576bb37a8562f3a4 (MD5) Previous issue date: 2016-12-20
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
ntrodução: O Melanoma é a principal neoplasia em cavidade oral de cães domésticos. Ocorre principalmente em gengiva, e caracteriza-se pela progressão acelerada, altos índices de recidiva, metástase e resistência a terapias propostas. Tais aspectos impulsionaram o presente estudo, considerando a ausência de um modelo experimental para essa neoplasia, que possibilite a realização de ensaios pré-clínicos. Objetivos: Induzir a formação de melanoma oral murino em camundongos C57Bl/6J, e estudar suas características macroscópicas e histopatológicas. Método: trata-se de um estudo experimental. Trinta camundongos C57Bl/6J (Mus musculus) foram submetidos a indução tumoral através da injeção de células da linhagem de melanoma murino B16F10 em gengiva inferior direita porção vestibular, em duas concentrações celulares, originando dois grupos distintos: Grupo 1 (n=15) que receberam 0,1 ml contendo 1x104 células de melanoma murino B16F10; Grupo 2 (n=15) que receberam 0,1 ml contendo 5x104 células de melanoma murino B16F10. Para ambos os grupos foram realizadas eutanásias programadas aos sétimo, décimo quarto e vigésimoprimeiro dias de pós-operatório, com ressecção ex-vivo da hemicabeça direita. Após a exclusão dos indivíduos que foram a óbito antes do período determinado para eutanásia, obteve-se um número de indivíduos na amostra (n) de 21. Foi realizada análise macroscópica das formações tumorais. Para o estudo histológico comparativo, analisaram-se amostras de melanoma oral canino melânico no que tange aos aspectos morfométricos e morfológicos. Resultados: Houve diferença no desenvolvimento tumoral para cada concentração celular utilizada na indução. Notouse correlação positiva entre volume tumoral e número de células. Conclusão: A indução de melanoma oral em camundongos para fins de modelo de estudo pré-clínico para cães se mostrou uma alternativa útil, viável e reproduzível.
Introduction: Melanoma is the most common neoplasm in oral cavity of dogs. Melanoma has a predilection for the gum, and it is characterized by accelerated progression and high rates of relapse, metastasis and resistance to proposed therapies. Those factors inspires the present study, considering the lack of an experimental model for melanoma. Method: This is an experimental study. Thirty C57Bl / 6J mice (Mus musculus) were submitted to tumor induction by injecting murine melanoma B16F10 cells into the right lower gum using two different cell concentrations. Mice were divided in two groups: Group 1 (n = 15) received 1x104 murine melanoma B16F10 cells injection; Group 2 (n = 15) received 5x104 murine melanoma B16F10 cells injections. For both groups, euthanasia was scheduled at the 7th., 14th. and 21th. postoperative day, with post-mortem hemi-resection of the jaw. Individuals who died before the euthanasia period were excluded, leaving 21 mice. Macroscopic analysis of tumor formations was performed. For comparative histological study, oral canine melanoma samples were analyzed for morphological aspects. Data sete analyzed with BioStat 5.3 and submitted to non-parametric statistical tests. Results: Different tumor characteristics (tumor volume, presence of irregular margins, ulceration and dark coloration) were observed for each cell concentration used in the induction, as well perfect correlation between tumor volume and tumor growth. Conclusion: The induction of oral melanoma in mice for purposes of preclinical study model for dogs is an useful, viable and reproducible alternative.
NORDIO, LAURA. "COMPARATIVE EVALUATION OF PROGNOSTIC MARKERS IN CANINE AND FELINE MELANOMAS." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/625608.
Full textDi, Palma Stefano <1978>. "Canine oral malignant melanoma: genomic and immunohistochemical approaches to better characterize the metastatic dissemination to the lymph node." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2020. http://amsdottorato.unibo.it/9165/1/OMM%20thesis%2031102019%20final%202020.pdf.
Full textNishiya, Adriana Tomoko. "Administração intratumoral de uma toxina engenheirada ativada por uroquinase (UPA) e metaloproteinase (MMP) para o tratamento do melanoma oral canino: estudo piloto." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/5/5155/tde-06042018-132036/.
Full textMalignant melanomas in dogs are one of the most frequent malignancies diagnosed in the oral cavity. Local infiltration, recurrence (15-41%) and the high potential for regional lymph nodes metastases (18-53%) and lungs (23-27%) in the affected animals, confer a lower survival (131-818 days), emphasizing the necessity and importance of the study of new therapies for the effective treatment of the disease. Urokinase (UPA) and metalloproteinases (MMPs) are overexpressed proteases in a variety of tumor cells and are rarely present in normal physiological cells. Bacillus anthracis toxin is composed of three proteins called lethal factor (LF), edema factor (EF) and protective antigen (PA). The toxin was re-engineered for the formation of two types of PAs called PAU2-R200A and PAL1-I207R, activated by UPA and MMPs from the surface of tumor cells, respectively, forming a cell-like complex to allow the internalization of the LF. The cytotoxicity of this association PAU2-R200A, PAL1-I207R and LF occurs when LF reaches the intracellular environment and causes cell death by disruption of the MAPkinase cell signaling pathway. The objective of this study is to evaluate the therapeutic potential of UPA and MMP-dependent Bacillus anthracis toxin (PAU2- R200A, PAL1-I207R and LF) to treat oral melanomas in dogs. Three steps were proposed: cytotoxicity assay of 5 lineages of canine melanomas submitted to the reengineered toxin, immunohistochemistry study for UPA and MMP expression in paraffin samples of canine oral melanoma and intratumoral treatment with toxin in dogs with spontaneous oral melanomas. The lineage GMGD2 was the only one that showed sensitivity to the toxin studied, although 50% inhibitory concentration of the cells was high (IC50 = 4,964.16 mg / dl) in relation to the HT29-RJ control lineage (IC 50 = 179.47). Among the samples of melanomas submitted to immunohistochemistry, 76.6% expressed both urokinase and metalloproteinases. Spontaneous oral melanomas of dogs ranging volume from 231.8 to 18601.6 mm3 with no evidence of distant metastases, were treated with the applications of intratumoral re-engineered toxin prior to surgical excision. All of them has presented favorable evolution classified as stable disease and partial response. Only one animal had a local allergic reaction. None of the patients had a significant systemic side effects. The results suggest that there is a potential therapeutic effect of re-engineered anthrax toxin on canine melanomas and future clinical trials are possible in dogs and extremely important for further studies on the role of the B. anthracis toxin as a new antineoplastic agent
Hsiung, Yu-Hsing, and 熊祐興. "Detection of differential antigens expression in canine oral melanomas and construction of Melan-A expression plasmid." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/73172260077935091886.
Full text國立中興大學
獸醫學系暨研究所
97
Melanoma is the most common malignant neoplasm of oral cavity in dogs. Metastasis of this cancer is associated with poor durable response to chemotherapy or any other known treatments. Melanoma differential antigens (e.g., Melan-A, tyrosinase and gp100), which are commonly recognized by the immune system, were highly expressed in melanoma lesions. Immunohistochemistry was used to detect the expression of differential antigens of the oral melanomas obtained from the Veterinary Medical Teaching Hospital of National Chung Hsing University. All four immunohistochemistry markers showed 100 % positivity. Based on the results of immunohistochemistry staining, Melan-A was chosen with a multiepitope sequence (gp100 (280V), gp100 (210M), tyrosinase (370D) to generate an immunogenic agent for canine melanoma therapy. In our present study, Melan-A was successfully amplified from human melanoma cell line A375.S2c and was subsequently cloned into pET32a and pcDNA3.1 vector for expression in prokaryotic and mammalian system, respectively. Melan-A expression had also been detected by Western blot. The partial fragment containing two repeats of multiepitope sequence was also obtained by PCR.
Campos, André Filipe Pedro. "O rácio neutrófilo-linfócito como fator de prognóstico para melanomas da cavidade oral em cães." Master's thesis, 2019. http://hdl.handle.net/10437/9446.
Full textO melanoma é uma neoplasia dos melanócitos, células que estão presentes em diversas localizações, como a pele, mucosa oral e junções mucocutâneas do lábio e dos dígitos. Esta é a neoplasia oral mais comum em cães, tendo por norma um comportamento bastante agressivo. Dada a natureza desta neoplasia, que na maioria dos casos apresenta um mau prognóstico associado a um tempo de sobrevida curto mesmo com recurso a tratamento, nasce a necessidade de dar uma resposta mais urgente no momento da sua suspeita quanto à previsibilidade do seu comportamento. De forma a perceber quais os fatores de prognóstico mais importantes no melanoma e a sua relação com a sobrevida, realizou-se uma revisão sistemática da literatura, na qual se pôde verificar que os fatores de prognóstico com maior frequência de avaliação são o índice mitótico, o índice de Ki67 e a dimensão tumoral. O presente trabalho tem como objetivo avaliar o significado prognóstico da resposta inflamatória e imunitária do organismo, através do cálculo do rácio neutrófilo/linfócito no momento do diagnóstico de melanoma oral, e perceber como se traduzem os resultados obtidos no prognóstico e sobrevida dos animais. Avaliaram-se então, os hemogramas de 16 cães diagnosticadas com melanoma oral, obtendo-se assim uma mediana para o rácio neutrófilo/linfócito de 3,7. Esta mediana foi usada como valor ‘cut-off’, que quando avaliado em relação à sobrevida, permitiu concluir que os cães com um valor inferior a este, atingiram uma mediana de sobrevida de 13 meses, enquanto que os cães com um rácio superior a este apresentarem uma mediana de sobrevida de apenas 7 meses. Encontrando assim uma diferença estatisticamente significativa (p = 0,044) na comparação entre os 2 grupos, e concluindo que o rácio neutrófilo/linfócito possui valor como indicador prognóstico neste estudo.
Melanoma is a neoplasm originating in menalocytes that are present in various locations, such as the skin, oral mucosa and mucocutaneous joints of the lip and digits. This is the most common oral neoplasia in dogs, with a very aggressive behavior. Given the nature of this neoplasm, which in most cases is presented with a poor prognosis associated with a short survival time even with treatment, the need arises to give a more urgent response at the time of its suspicion of the predictability of its behavior. In order to understand the most important prognostic factors in melanoma and its relation with survival, a systematic review of the literature was carried out, in which it was verified that the prognostic factors with higher frequency of evaluation are the mitotic index, Ki67 index and the tumor size. The present study aims to evaluate the prognostic significance of the inflammatory and immune response of the organism by calculating the neutrophil / lymphocyte ratio at the time the oral melanoma is diagnosed and to understand how the results obtained in the prognosis and survival are translated for the animals. Hemograms of 16 dogs diagnosed with oral melanoma were then evaluated, resulting in a median for the neutrophil / lymphocyte ratio of 3.7. This median was used as a cut-off value, which when evaluated in relation to survival, allowed to conclude that dogs with a lower value reached a median survival of 13 months, while dogs with a ratio higher than have a median survival of only 7 months. Finding a statistically significant difference (p = 0.044) in the comparison between the 2 groups, and concluding that the neutrophil / lymphocyte ratio was a useful prognostic indicator in this study.
Book chapters on the topic "Canine oral melanoma"
Gavin, P. R., S. L. Kraft, C. E. DeHaan, R. D. Sande, M. Papageorges, and W. F. Bauer. "Spontaneous Canine Oral Melanoma: A Large Animal Model for BNCT." In Progress in Neutron Capture Therapy for Cancer, 411–15. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3384-9_91.
Full textPloypetch, Sekkarin, Sittiruk Roytrakul, and Gunnaporn Suriyaphol. "Salivary Proteomic Analysis of Canine Oral Melanoma by MALDI-TOF Mass Spectrometry and LC-Mass Spectrometry/Mass Spectrometry." In Methods in Molecular Biology, 429–45. New York, NY: Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1205-7_31.
Full textBlacklock, Kelly Bowlt, Zeynap Birand, Laura Selmic, Pieter Nelissen, Sue Murphy, Laura Blackwood, Joyce Bass, et al. "Genome-wide analysis of canine oral malignant melanoma (OMM) metastasis-associated gene expression." In BSAVA Congress Proceedings 2019, 453–54. British Small Animal Veterinary Association, 2019. http://dx.doi.org/10.22233/9781910443699.67.4.
Full textConference papers on the topic "Canine oral melanoma"
Pereira, Mariana Soares. "USO DE QUIMIOTERAPIA E ELETROQUIMIOTERAPIA NO CONTROLE DE MELANOMA ORAL AMELANÓTICO CANINO - RELATO DE CASO." In I Congresso On-line Nacional de Clínica Veterinária de Pequenos Animais. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/1922.
Full textRoss, Maria Laura da Rosa Dal, Vinícius Rosa Dos Santos, Luísa Sant Anna Blaskoski Cardoso, and Julia Da Costa Cunha. "MELANOMA AMELANÓTICO EM FELINO: RELATO DE CASO." In I Congresso On-line Nacional de Clínica Veterinária de Pequenos Animais. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/1933.
Full text