Relevant bibliographies by topics / Cancer in children Epidemiology

Academic literature on the topic 'Cancer in children Epidemiology'

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Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "Cancer in children Epidemiology"

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Piovesan, Dana, Chantal Attard, Paul Monagle, and Vera Ignjatovic. "Epidemiology of venous thrombosis in children with cancer." Thrombosis and Haemostasis 111, no. 06 (2014): 1015–21. http://dx.doi.org/10.1160/th13-10-0827.

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SummaryThere has been an extensive body of research focusing on the epidemiology of thrombosis in adult cancer populations; however, there is significantly less knowledge about thrombosis in paediatric cancer populations. Thrombosis is diagnosed with increasing frequency in children being treated for cancer, and there is an urgent need to increase our understanding of the epidemiology of thrombosis in this population. Currently, there are no guidelines for identification of high-risk groups, prophylaxis or management of thrombotic complications in paediatric cancer patients. We reviewed the available literature regarding the epidemiology, mechanisms, risk factors, prophylaxis and outcomes of thrombosis in children with cancer and identified areas that require further research. The reported incidence of symptomatic venous thromboembolism (VTE) in children with cancer ranges between 2.1% and 16%, while the incidence of asymptomatic events is approximately 40%. Approximately 30% of VTE in this population is associated with central venous lines (CVL). The most common location of VTE is upper and lower extremity deep venous thrombosis (43 to 50% of events, respectively), while 50% of events in ALL patients occur in the central nervous system. Key characteristics that increase the risk of thrombosis include the type of cancer, age of the patient, the presence of a CVL, presence of pulmonary/intra thoracic disease, as well as the type of chemotherapy. Outcomes for paediatric cancer patients with VTE include post-thrombotic syndrome, pulmonary embolism, recurrent thromboembolism, destruction of upper venous system and death. Prospective studies aimed at enabling risk stratification of patients are required to facilitate development of paediatric specific recommendations related to thromboprophylaxis in this population.
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Horner, Marie-Josèphe, Ande Salima, Chrissie Chilima, Matthews Mukatipa, Wiza Kumwenda, Coxcilly Kampani, Fred Chimzimu, et al. "Frequent HIV and Young Age Among Individuals With Diverse Cancers at a National Teaching Hospital in Malawi." Journal of Global Oncology, no. 4 (December 2018): 1–11. http://dx.doi.org/10.1200/jgo.17.00174.

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Purpose Cancer surveillance provides a critical evidence base to guide cancer control efforts, yet population-based coverage in Africa is sparse. Hospital-based registries may help fill this need by providing local epidemiologic data to guide policy and forecast local health care needs. We report the epidemiology of patients with cancer recorded by a de novo hospital-based cancer registry at Kamuzu Central Hospital, Malawi, the sole provider of comprehensive oncology services for half the country and location of a high-volume pathology laboratory. Methods We conducted active case finding across all hospital departments and the pathology laboratory from June 2014 to March 2016. Patient demographics, tumor characteristics, treatment, and HIV status were collected. We describe epidemiology of the cancer caseload, registry design, and costs associated with registry operations. Results Among 1,446 registered patients, Kaposi sarcoma and cervical cancer were the most common cancers among men and women, respectively. Burkitt lymphoma was most common cancer among children. The current rate of pathology confirmation is 65%, a vast improvement in the diagnostic capacity for cancer through the hospital’s pathology laboratory. Among leading cancer types, an alarming proportion occurred at young ages; 50% of Kaposi sarcoma and 25% of esophageal, breast, and cervical cancers were diagnosed among those younger than 40 years of age. A systematic, cross-sectional assessment of HIV status reveals a prevalence of 58% among adults and 18% among children. Conclusion We report a high caseload among typically young patients and a significant burden of HIV infection among patients with cancer. In low- and middle-income countries with intermittent, sparse, or nonexistent cancer surveillance, hospital-based cancer registries can provide important local epidemiologic data while efforts to expand population-based registration continue.
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Abood, Rafid A., Kareem A. Abdahmed, and Seena S. Mazyed. "Epidemiology of Different Types of Cancers Reported in Basra, Iraq." Sultan Qaboos University Medical Journal [SQUMJ] 20, no. 3 (October 5, 2020): 295. http://dx.doi.org/10.18295/squmj.2020.20.03.008.

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Objectives: This study aimed to report the incidence and pattern of various types of cancers and their distribution across various demographic groups in Basra, Iraq. Methods: Cancer cases recorded during 2017 at the Basra Cancer Control Centre, the Department of Pathology and Forensic Medicine, the Basra Oncology and Hematology Centre, the Basra Children’s Hospital and at private laboratories were included in the study. Patients’ records were analysed for information related to age, gender, residence and type of cancer. Incidences for different geographical regions and distribution of incidences across age groups were recorded as percentages. The mean age was recorded for patients of different genders and age groups. Incidence rates per 100,000 were calculated for different types of cancer. Results: A total of 2,163 cancer cases were identified of which 2,020 were in adults (93.4%) and 143 were in children (6.6%). Among adults, most cancers were found in females (59%). Patients’ mean age at diagnosis was 51.4 ± 19.6 years for adults and 6.4 ± 4.23 years for children. Cancer incidence rates per 100,000 people increased with age. Breast cancer was the most frequent cancer type found in adult females, with an incidence rate of 60.64 per 100,000 people. The most common types of cancer found in adult males were urinary bladder and lung and bronchus cancers; leukaemia was the most common cancer in children. Conclusion: The findings from this study can be used for predicting cancer epidemiology in Basra, Iraq, and to identify subsets of the population at high risk of cancer incidence. This information will help healthcare providers to adequately respond to the demands of diagnosis, treatment and palliative care for such patients.Keywords: Neoplasms; Incidence; Epidemiology; Demography; Iraq.
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Stacy, Shaina L., Jeanine M. Buchanich, Zhen-qiang Ma, Christina Mair, Linda Robertson, Ravi K. Sharma, Evelyn O. Talbott, and Jian-Min Yuan. "Maternal Obesity, Birth Size, and Risk of Childhood Cancer Development." American Journal of Epidemiology 188, no. 8 (May 20, 2019): 1503–11. http://dx.doi.org/10.1093/aje/kwz118.

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Abstract Infants and children are particularly vulnerable to in utero and early-life exposures. Thus, a mother’s exposures before and during pregnancy could have important consequences for her child’s health, including cancer development. We examined whether birth certificate–derived maternal anthropometric characteristics were associated with increased risk of subsequent childhood cancer development, accounting for established maternal and infant risk factors. Pennsylvania birth and cancer registry files were linked by the state Department of Health, yielding a virtual cohort of births and childhood cancers from 2003 through 2016. The analysis included 1,827,875 infants (13,785,309 person-years at risk), with 2,352 children diagnosed with any cancer and 747 with leukemia before age 14 years. Children born to mothers with a body mass index (weight (kg)/height (m)2) of ≥40 had a 57% (95% confidence interval: 12, 120) higher leukemia risk. Newborn size of ≥30% higher than expected was associated with 2.2-fold and 1.8-fold hazard ratios for total childhood cancer and leukemia, respectively, relative to those with expected size. Being <30% below expected size also increased the overall cancer risk (P for curvilinearity < 0.0001). Newborn size did not mediate the association between maternal obesity and childhood cancer. The results suggest a significant role of early-life exposure to maternal obesity- and fetal growth–related factors in childhood cancer development.
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Sung, T. I., P. C. Chen, and J. D. Wang. "Cancer in Children of Electronics Industry Employees." Epidemiology 17, Suppl (November 2006): S188. http://dx.doi.org/10.1097/00001648-200611001-00476.

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Heath, John A., Elizabeth Smibert, Elizabeth M. Algar, Gillian S. Dite, and John L. Hopper. "Cancer Risks for Relatives of Children with Cancer." Journal of Cancer Epidemiology 2014 (2014): 1–4. http://dx.doi.org/10.1155/2014/806076.

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We determined the extent and distribution of cancers in relatives of 379 children newly diagnosed with cancer. Family history was collected from 1,337 first-degree and 3,399 second-degree relatives and incidence compared with national age- and gender-specific rates. Overall, 14 children (3.7%) had a relative with a history of childhood cancer and 26 children (6.9%) had a first-degree relative with a history of cancer, with only one of these having an identifiable familial cancer syndrome. There was a higher than expected incidence of childhood cancer among first-degree relatives (parents and siblings) (standardized incidence ratio (SIR) 1.43; 95% CI 0.54–5.08). There was also a higher than expected incidence of adult cancers among first-degree relatives (SIR 1.45; 95% CI 0.93–2.21), particularly in females (SIR 1.82; 95% CI 1.26–3.39). The increased family cancer history in first-degree females was largely attributable to an effect in mothers (SIR 1.78; 95% CI 1.27–3.33). The gender-specific association was reflected in higher than expected incidence rates of breast cancer in both mothers (SIR 1.92; 95% CI 0.72–6.83) and aunts (SIR 1.64; 95% CI 0.98–2.94). These findings support the hypothesis that previously undetected familial cancer syndromes contribute to childhood cancer.
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Saab, Raya, and Wayne L. Furman. "Epidemiology and Management Options for Colorectal Cancer in Children." Pediatric Drugs 10, no. 3 (2008): 177–92. http://dx.doi.org/10.2165/00148581-200810030-00006.

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Padma, Maneya, Nuthan Kumar, Prerana S. Nesargi, B. S. Aruna Kumari, L. Appaji, and Aarthi Viswanathan. "Epidemiology and clinical features of retinoblastoma." South Asian Journal of Cancer 09, no. 01 (January 2020): 56–58. http://dx.doi.org/10.4103/sajc.sajc_89_19.

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Abstract Introduction: Retinoblastoma (RB) is a prototype of heritable cancers. It is more common in the lower socioeconomic strata. Delayed presentation significantly reduces the overall outcome. We have analyzed the epidemiological and clinical data of children who were diagnosed with RB between the years 2009 and 2014. Aim: RB being a disease of the poor, delayed presentation is common due to lack of awareness. We have analyzed the epidemiological profile of our patients and tried to establish the link between delayed presentation and the presence of high-risk features. High-risk features are associated with higher chance of metastasis and poor rates of vision salvage in RB. Methodology: Data were collected in a retrospective manner from the patient case files retrieved from the Medical Records Department, Kidwai cancer Institute. The data were analyzed using Excel and SPSS software (IBM Corp. released 2016, IBM SPSS statistics software for Mac OS, version 24, IBM Corp., Armonk, NY). Results: A total of 53 patients were diagnosed with RB in the years 2009–2014. There was a male predominance with 1.2:1 incidence. Bilateral RB was present in 21 cases. The mean age of children with bilateral RB was 2.1 years, against 1.5 years in unilateral cases. High-risk features such as optic nerve invasion, choroidal invasion, intracranial extension, and orbital involvement were found in 12, 6, 5, and 5 eyes, respectively. Bone marrow involvement was detected in 5% and lung metastasis in 2%. Intracranial involvement was found in 10.4% and cerebrospinal fluid positivity in 15%. Children with high-risk features had a significant delay in presentation in comparison to those without high-risk features (P = 0.035). Conclusion: Incidence of metastatic disease and delayed presentation is still high in developing countries. Routine eye examination during vaccination visits can ensure early diagnosis and appropriate referral in many of these children.
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Bunin, Greta R., Tanya S. Surawicz, Philip A. Witman, Susan Preston-Martin, Faith Davis, and Janet M. Bruner. "The descriptive epidemiology of craniopharyngioma." Journal of Neurosurgery 89, no. 4 (October 1998): 547–51. http://dx.doi.org/10.3171/jns.1998.89.4.0547.

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Object. In this report the authors describe the epidemiology of craniopharyngioma. Methods. The incidence of craniopharyngioma in the United States was estimated from two population-based cancer registries that include brain tumors of benign and borderline malignancy: the Central Brain Tumor Registry of the United States (CBTRUS) and the Los Angeles county Cancer Surveillance Program. Information on additional pediatric tumors was available from the Greater Delaware Valley Pediatric Tumor Registry (GDVPTR). The overall incidence of craniopharyngioma was 0.13 per 100,000 person years and did not vary by gender or race. A bimodal distribution by age was noted with peak incidence rates in children (aged 5–14 years) and among older adults (aged 65–74 years in CBTRUS and 50–74 years in Los Angeles county). Survival information was available from GDVPTR and the National Cancer Data Base (NCDB), a hospital-based reporting system. In the NCDB, the 5-year survival rate was 80% and decreased with older age at diagnosis. Survival is higher among children and has improved in recent years. Conclusions. Craniopharyngioma is a rare brain tumor of uncertain behavior that occurs at a rate of 1.3 per million person years. Approximately 338 cases of this disease are expected to occur annually in the United States, with 96 occurring in children from 0 to 14 years of age.
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Bunin, Greta R., Tanya S. Surawicz, Philip A. Witman, Susan Preston-Martin, Faith Davis, and Janet M. Bruner. "The descriptive epidemiology of craniopharyngioma." Neurosurgical Focus 3, no. 6 (December 1997): E3. http://dx.doi.org/10.3171/foc.1997.3.6.4.

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The incidence of craniopharyngioma in the United States was estimated from two population-based cancer registries that include brain tumors of benign and borderline malignancy: the Central Brain Tumor Registry of the United States (CBTRUS) and Los Angeles county. Information on additional pediatric tumors was available from the Greater Delaware Valley Pediatric Tumor Registry (GDVPTR). The overall incidence of craniopharyngioma was 0.13 per 100,000 person years and did not vary by gender or race. A bimodal distribution by age was noted with peak incidence rates in children (aged 5-14 years) and among older adults (aged 65-74 years in CBTRUS and 50-74 years in Los Angeles county). Survival information was available from GDVPTR and the National Cancer Data Base (NCDB), a hospital-based reporting system. In the NCDB, the 5-year survival rate was 80% and decreased with older age at diagnosis. Survival is higher among children and has improved in recent years. Approximately 338 cases of craniopharyngiomas are expected to occur annually in the United States, with 96 occurring in children from 0 to 14 years of age.
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Dissertations / Theses on the topic "Cancer in children Epidemiology"

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KRALLMAN, KELLI ALICIA. "The Cancerogenic Effects of Exposure to Uranium: Are Children More At Risk?" University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1218647724.

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Davis, Jonathan. "Cancer risk in children of agricultural health study participants." Diss., University of Iowa, 2017. https://ir.uiowa.edu/etd/5926.

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This study examines the risk of cancer in children of pesticide applicators from the Agricultural Health Study. The study includes 36,537 children of Iowa participants who were evaluated for cancer incidence during 1975 through 2013 from birth through the age of seventeen. Standard incidence rates for any cancer and specific groups of cancers classified using the International Classification of Childhood Cancer was calculated using rates from the general population of Iowa controlling for year of follow, age, sex, and race. Hazard ratios for Group I-III cancers and paternal exposure to specific pesticides were calculated using exposure information collected on 50 pesticides during phase 1 and 2 of the Agricultural Health Study. The exposure information allowed for calculation of intensity-weighted days of exposure to pesticides using the Agricultural Health Study exposure algorithm. Additionally, maternal ever exposure to specific pesticides was used to evaluate risk of childhood cancer. There were 118 cancers identified in children of Agricultural Health Study participants. The all-cancer standardized incidence ratio was significantly elevated (SIR = 1.27 95% CI: 1.04-1.50). The most common groups of cancers were Group I leukemia, myeloproliferative disease, and myelodysplastic disease (n=34) followed by Group III central nervous system (CNS) and miscellaneous intracranial and intraspinal neoplasms (n=25). For paternal intensity-weighted days of exposure, there were 31 of 50 specific pesticides that had sufficient cases of cancer to investigate using Cox proportional hazard models. The herbicide trifluralin significantly increased the risk for Group I childhood cancers for any parental pesticide exposure 2 years before birth through birth when compared to children with no paternal exposure (HR = 2.72 95% CI: 1.15, 6.44). This was consistent with results found from analyzing exposure split into two quantiles based on median exposure of exposed children with a Group I cancer. Parental use of the herbicide S-Ethyl-dipropylthiocarbamate (EPTC) did not result in a sufficient number of Group III cancer cases to look at levels of exposure to EPTC, but ever exposure showed an increased hazard ratio when compared to children with unexposed fathers (HR = 2.56 95% CI: 1.06, 6.20). Other pesticides (dicamba, cyanazine, and terbufos) showed mixed evidence of an association with specific childhood cancers, but were either under powered to evaluate with sensitivity analysis or showed inconsistent risk across exposure levels. Less extensive exposure information was available for mothers of children of the Agricultural Health Study, so analysis was restricted to ever or never exposure to pesticides during a mother’s lifetime. Additionally, there were a limited number of cases of cancer for which maternal exposure to specific pesticides was reported resulting in only 4 pesticides being evaluated for childhood cancer risk (glyphosate, 2,4-dichlorophenoxyacetic acid (2,4-D), carbaryl, and malathion). For these four pesticides, this study did not detect any increased risk of childhood cancer from maternal exposure. In summary, this study provides the first epidemiological evidence of an increased risk of childhood cancer for trifluralin and EPTC. Since this study provides the first evidence of this increased risk, additional analysis is needed to validate the results. This study demonstrates how pesticide exposure information from participants of the AHS can be used in the evaluation of their children’s cancer risk. Additional follow-up and analysis of this cohort beyond the age of 17 would provide further insight into cancer risk during early adulthood from early life pesticide exposure.
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Dang-Tan, Tam 1976. "Epidemiology of delays in care of children and adolescents diagnosed with cancer in Canada." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=115664.

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Background: Although rare relative to adult cancers, cancer is still the leading cause of disease-related death in children in developed countries, including Canada. Few studies have specifically examined the epidemiology and public health significance of diagnosis and treatment delays in childhood cancer. This study aimed to investigate the nature of delays in care for children and adolescents with cancer in Canada and to assess the potential impact of such delays on clinical outcomes.
Study Design: I conducted a prospective cohort study to investigate the delays of cancer symptoms reporting, diagnosis, and treatment in children between 0-19 years of age in Canada. This study used a database from Health Canada's Treatment and Outcomes component of the Canadian Childhood Cancer Surveillance and Control Program.
Methodology: Patients were identified from 17 paediatric cancer centres across Canada. Subjects included in this study were residents of Canada, aged less than 20 years, diagnosed with a malignant tumour and had information on date of first symptoms, diagnosis, treatment and outcome available. Descriptive statistics and regression techniques (linear, logistic and Cox regression) were used as appropriate. I measured the individual impact of patient and provider delays on disease severity and prognosis by using judicious control for potential confounding mechanisms and mediating factors.
Study Findings and Significance: By measuring various types of delays in Canada, I found that varying lengths of patient and referral delay, across age groups, types of cancers, and Canadian settings, are the main contributors to diagnosis, HCS and overall delay. Factors relating to the patients, the parents, healthcare and the cancer may all exert different influences on different segments of cancer care. I also found a negative association between diagnosis delay and disease severity for lymphoma and CNS tumour patients. Furthermore, I found that diagnosis and physician delay had a negative effect, while patient delay had a positive effect, on survival for patients diagnosed with CNS tumours. The information provided from this study may form the basis for new effective policies aimed at eliminating obstacles in cancer the diagnostic and care trajectories for Canadian children with cancer and for improving their prognosis.
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Oliveira, Friestino Jane Kelly 1984. "Panorama do câncer em crianças e adolescentes sob a perspectiva da Saúde Coletiva = Overview of cancer among children and adolescents in the perspective of Collective Health." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312569.

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Orientador: Djalma de Carvalho Moreira Filho
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
Made available in DSpace on 2018-08-27T20:51:08Z (GMT). No. of bitstreams: 1 OliveiraFriestino_JaneKelly_D.pdf: 2892489 bytes, checksum: fdc2a35ce3e46aaf292c913864bc673d (MD5) Previous issue date: 2015
Resumo: A assistência à saúde da criança e adolescente necessita contemplar as particularidades e características intrínsecas a essa fase da vida. Os cânceres que acometem crianças e adolescentes têm fatores de riscos e características que diferem daqueles que acometem a população adulta. No Brasil, pouco se conhece a respeito da magnitude das neoplasias no universo infanto-juvenil, bem como as características da população acometida. Objetivou-se estudar o panorama do câncer em crianças e adolescentes sob a perspectiva da Saúde Coletiva, e neste âmbito, apontar ferramentas de monitoramento; conhecer as dificuldades e percepções dos profissionais de saúde que atuam na atenção básica, em relação a suspeita e diagnóstico de câncer em crianças; e, analisar os padrões de distribuição espacial das incidências e sobrevivências de crianças diagnosticadas com neoplasias. Para atender aos objetivos, foram utilizados métodos qualitativos e quantitativos com dados obtidos em Registros de Câncer de Base Populacional e também em Grupos Focais realizados com trabalhadores da Atenção Primária à Saúde. Os resultados foram apresentados em capítulos correspondentes a três artigos. No primeiro artigo, "Câncer Infantil: monitoramento da informação através dos Registros de Câncer de Base Populacional RCBP", realizou-se uma pesquisa bibliográfica da incidência de tumores raros em menores de 20 anos, em três países. Nesta busca identificou-se que a primeira publicação específica sobre câncer em crianças e adolescentes no Brasil foi divulgada em 2008. As publicações do Brasil, Alemanha e Estados Unidos apresentam as informações com critérios heterogêneos, tanto em relação ao modo como a incidência é apresentada, quanto em relação à faixa etária adotada. No segundo trabalho, "Suspeita e Diagnóstico de Câncer em Crianças e Adolescentes na Atenção Primária à Saúde", foram identificados pontos fortes e fragilidades no que concerne ao sentimento dos profissionais; a suspeita e diagnóstico na rede de cuidados primários e a relação dos profissionais e a família. Em todas as categorias de profissionais, as percepções foram negativas com demonstração de insegurança em relação ao tema na atenção básica. No terceiro estudo, "Câncer em crianças e adolescentes: incidência e sobrevivência no município de Campinas-SP, Brasil", os resultados apontaram taxa de incidência global para os grupos de Leucemias (Grupo I); Linfomas (Grupo II); Tumores do Sistema Nervoso Central (Grupo III) e Sarcomas de Partes Moles (Grupo IX) de 54,2 por milhão, com uma incidência padronizada de 59,1 por milhão (Grupo I¿28,8; Grupo II-11,6; Grupo III-7.5 e Grupo IX-4,3). Diferenças nos padrões espaciais não foram encontradas. Diferenças significativas em tempos de sobrevivência foram verificadas por Grupos de diagnóstico ajustados para idade e sexo (p=0,001). Os achados desse estudo demonstraram diferentes possibilidades de abordagem do câncer infantil utilizando o saber científico da Epidemiologia. Os resultados apontam para a necessidade de uma sistematização das informações de tumores raros na infância e na adolescência, e uma inclusão do tema câncer infantil aos profissionais de saúde que atuam na Atenção Primária à Saúde. A utilização de metodologias epidemiológicas como análise da incidência, uso da estatística espacial e análises de sobrevivência contribuem para a construção do panorama do câncer infantil na Saúde Coletiva.
Abstract: The health care to the children and adolescents needs to contemplate the particularities and intrinsic characteristics of this phase of life. Occurrences of childhood cancer have risk factors and specific characteristics that differ from tumours in adults. In Brazil, little is known about the magnitude of childhood cancer, as well as the characteristics of the affected population. Our goal to study cancer among children and adolescents in the perspective of Collective Health, and in this context, point monitoring tools in the health information systems; identify the difficulties and perceptions of workers in primary health care, in relation to suspicion and diagnosis of childhood cancer; and finally analyse the distribution patterns of spatial incidence and survival of children who have been diagnosed with cancer. To achieve the objectives, we used qualitative and quantitative methods with data by Population-based Cancer Registries and also in focus groups conducted with workers of Primary Health Care. Results are presented in three articles on chapters. In the first article, "Childhood Cancer: Information Followed in Population-Based Cancer Registry", we conducted a literature search of tumours incidence in children under 20 years of age in three countries. This research identified that first specific publication about cancer among children and adolescents in Brazil was released in 2008. Publications of Brazil, Germany and the United States have the information with heterogeneous criteria, both in relation to how the incidence is presented and in relation to age adopted, being difficult to compare. In the second study, "Suspicion and Diagnosis of Cancer among Children and Adolescents in Primary Health Care", were identified strong points and weaknesses concerning regarding feeling of professionals, suspicion and diagnosis the primary care network and relationship between professionals and family. In all professional¿s categories perceptions were negative with demonstration of insecurity in primary care. In the study, "Cancer Incidence and survival among children and adolescents in Campinas ¿ SP, Brazil", the results showed overall crude incidence rate for Leukaemia (Group I); Lymphomas (Group II); CNS neoplasms (Group III), and Soft tissue sarcomas (Group IX) was 54.2 per million and standardized incidence rates was 59.1 (Group I-28.8, Group II-11.6, Group III-7.5 and Group IX-4.3). Spatial differences were not found. Significant differences in survival times were found by diagnostic Groups adjusted for age and sex (p=0.001). In conclusion, higher incidence was found in Group-I and 5-year survival is higher in children than in adolescents similar to the findings reported in the literature. The findings of this study showed different approach possibilities of childhood cancer using scientific knowledge of collective health. The results indicate the need for systematic information of rare tumours in childhood, and including the theme to health professionals working in primary health care. The use of such epidemiological methods analysis of incidence, use of spatial statistics and survival analyses contribute to the construction of the panorama of childhood cancer in Collective Health
Doutorado
Epidemiologia
Doutora em Saúde Coletiva
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Kroll, Mary Eileen. "Time trends in childhood cancer : Britain 1966-2005." Thesis, University of Oxford, 2009. http://ora.ox.ac.uk/objects/uuid:8be887be-36e7-4b77-a7af-5887f3a1df8c.

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Increasing time trends in the recorded incidence of childhood cancer have been reported in many different settings. The extent to which these trends reflect real changes in incidence, rather than improvements in methods for diagnosis and registration, is controversial. Using data from the National Registry of Childhood Tumours (NRCT), this thesis investigates time trends in cancer diagnosed under age 15 in residents of Britain during 1966-2005 (54650 cases), and considers potential sources of artefact in detail. Several different methods are used to estimate completeness of NRCT registration. The history of methods for diagnosis and registration of childhood cancers in Britain is described, and predictions are made for effects on recorded incidence. For each of the 12 main diagnostic groups, Poisson regression is used to fit continuous time trends and ‘step’ models to the annual age-sex-standardised rates by year of birth and year of diagnosis. Age-specific rates by period, and quinquennial standardised rates for diagnostic subgroups, are shown graphically. For three broad groups (leukaemia, CNS tumours and other cancer), geographical variation is compared by period of diagnosis. The results of these analyses are discussed in relation to the predicted artefacts. The evidence for a positive association between affluence and recorded incidence of childhood leukaemia is briefly reviewed. A special form of diagnostic artefact, the ‘fatal infection’ hypothesis, is proposed as an explanation of both this association and the leukaemia time trend. This hypothesis is examined in a novel test based on clinical data. The recorded incidence of childhood cancer in Britain increased in each of 12 diagnostic groups during 1966-2005 (from 0.5% per year for bone cancer to 2.5% for hepatic cancer, with 0.7% for leukaemia). Evidence presented here suggests that these increases are probably artefacts of diagnosis and registration. The potential implications for epidemiological studies of childhood cancer should be considered.
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Tanaka, Luana Fiengo. "A epidemiologia do câncer em crianças e adolescentes com Aids no Município de São Paulo: um estudo de base populacional." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/6/6132/tde-18042017-150014/.

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Introdução: A associação entre a infecção pelo vírus da imunodeficiência humana (HIV) e o câncer tem sido documentada desde os primórdios da epidemia da síndrome da imunodeficiência adquirida (Aids). A introdução da highly active antirretroviral therapy (HAART) alterou, profundamente, o curso da epidemia da Aids, reduzindo, drasticamente, a incidência de manifestações definidoras da síndrome, incluindo cânceres. No entanto, existem informações limitadas sobre a incidência de câncer em crianças e adolescentes com Aids vivendo em países em desenvolvimento. Objetivo: Descrever a epidemiologia do câncer em crianças e adolescentes com Aids no Município de São Paulo, no período de 1997 a 2012. Métodos: Trata-se de um estudo de base populacional, utilizando as bases de dados do Registro de Câncer de Base Populacional do Município de São Paulo e do Sistema de Informações de Agravos de Notificação (SINAN). As crianças e adolescentes (< 20 anos) com Aids e câncer foram identificadas por meio de um processo de linkage probabilístico entre as bases de dados supracitadas. Foram calculadas as taxas de incidência brutas e ajustadas por milhão de habitantes. Para comparar a incidência de câncer na população com Aids e a população geral foi calculada a razão de incidência padronizada (RIP) e respectivos intervalos de confiança de 95 por cento (IC 95 por cento ). A análise de tendência foi feita por meio do cálculo do annual percent change (APC) e IC 95 por cento correspondentes. A análise da sobrevida global de cinco anos após o câncer entre pacientes com Aids e na população geral foi calculada por meio do estimador produto limite de Kaplan-Meier e modelos univariados de riscos proporcionais de Cox. Mapas coropléticos em escalas monocromáticas foram gerados para descrever a distribuição de casos no Município. Resultados: Foram identificados 24 casos de câncer em pacientes com Aids menores de 20 anos, sendo 62,5 por cento cânceres definidores de Aids. Os cânceres mais incidentes foram o linfoma não Hodgkin, incluindo o linfoma de Burkitt (12; 50,0 por cento ), o linfoma de Hodgkin (6; 25,0 por cento ) e o sarcoma de Kaposi (3; 12,5 por cento ). A taxa bruta de incidência foi de 1.461,3 casos/milhão. A análise de tendência revelou redução significativa da incidência para todos os cânceres (APC= -14,5), influenciada pela queda nos cânceres definidores de Aids (APC= -17,0). O risco para câncer se mostrou aumentado (RIP= 3,9), sobretudo para o linfoma não Hodgkin, excluindo linfoma de Burkitt (RIP= 22,5), linfoma de Burkitt (RIP= 29,7) e linfoma de Hodgkin (RIP= 18,7). A probabilidade acumulada de sobrevida aos cinco anos foi de 56,3 por cento em crianças e adolescentes com Aids versus 87,5 por cento na população geral. A hazard ratio para óbito foi 5,2 (IC 95 por cento = 2,0; 13,6). O mapa da distribuição geográfica mostrou concentração dos casos nas áreas de classes sociais mais baixas do Município. Conclusão: Houve redução acentuada da incidência de cânceres definidores de Aids, como provável resultado da introdução da HAART. No entanto, crianças e adolescentes com Aids permanecem sob risco aumentado para o desenvolvimento de câncer quando comparadas à população geral. Para aquelas que desenvolveram câncer, o risco para óbito também se mostrou substancialmente elevado
Introduction: The association between human immunodeficiency virus (HIV) infection and cancer has been documented since the beginning of the epidemic of the acquired immunodeficiency syndrome (AIDS). The introduction of the highly active antiretroviral therapy (HAART) has profoundly altered the course of the AIDS epidemic, drastically reducing the incidence of AIDS-defining manifestations, including cancers. Nevertheless, there is limited information on the incidence of cancer in children and adolescents with AIDS living in developing countries. Objective: To describe the cancer epidemiology in children and adolescents with AIDS in the Municipality of São Paulo from 1997 to 2012. Methods: It is a population-based study, using the databases of the Population-based Cancer Registry of São Paulo and the Notifiable Diseases Information System (SINAN). Children and adolescents (< 20 years) with AIDS and cancer have been identified by means of a probabilistic record linkage process between the aforementioned databases. Crude and age-standardized incidence rates per million inhabitants were calculated. To compare the incidence of cancer in people with AIDS and that of the general population, standardized incidence ratio (SIR) and respective 95 per cent confidence intervals (95 per cent CI) were calculated. We examined trends by calculating the annual percent change (APC) and corresponding 95 per cent CI. The analyses of the overall five-year survival after cancer diagnosis among children and adolescents with AIDS and that of the general population were based on the Kaplan-Meier product limit estimator and univariate Cox proportional hazards models. Choropleth maps on monochromatic scales were generated to describe the distribution of cases across the Municipality. Results: We identified 24 cases of cancer in patients with AIDS aged 20 years and younger, of which, 62.5 per cent were AIDS-defining malignancies. The most incident cancers were non-Hodgkin\'s lymphoma, including Burkitt\'s lymphoma (12; 50.0 per cent ), Hodgkin\'s lymphoma (6; 25.0 per cent ) and Kaposi sarcoma (3; 12.5 per cent ). The age-standardized incidence rate was 1,461.3 cases/million. The trend analyses revealed a significant reduction in the incidence of all cancers (APC= -14.5), driven by the decrease in AIDS-defining cancers (APC= -17.0). The overall risk for cancer was significantly increased (SIR= 3.9), especially for non-Hodgkin lymphoma, excluding Burkitts lymphoma (SIR= 22.5), Burkitt\'s lymphoma (SIR= 29.7) and Hodgkin\'s lymphoma (SIR= 18.7). The overall probability of survival at five years after cancer was 56.3 per cent in children and adolescents with AIDS versus 87.5 per cent in the general population. The hazard ratio for death was 5.2 (95 per cent CI= 2.0, 13.6). The map of the geographical distribution showed a concentration of cases in the low-income areas of the Municipality. Conclusion: There was a marked reduction in the incidence of AIDS-defining cancers, likely to be a result of the introduction of HAART. However, children and adolescents with AIDS remain at increased risk for the development of cancer when compared to the general population. For those who developed cancer, the risk of death was also significantly higher
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Wiklund, Fredrik. "Genetic epidemiology of prostate cancer." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-281.

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Cheng, Kar Keung. "The epidemiology of oesophageal cancer." Thesis, University of Cambridge, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309275.

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Rigby, Janette Elizabeth. "An epidemiology of breast cancer." Thesis, Lancaster University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311870.

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Macfarlane, Gary John. "The epidemiology of oral cancer." Thesis, University of Bristol, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.357309.

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Books on the topic "Cancer in children Epidemiology"

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International Agency for Research on Cancer., ed. Epidemiology of childhood cancer. Lyon, France: International Agency for Research on Cancer, 1999.

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M, Parkin D., and International Agency for Research on Cancer., eds. International incidence of childhood cancer. Lyon: International Agency for Research on Cancer, 1998.

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Ballew, Carol. Childhood cancer in the Northern Plains states, 2001-2005: A four-state collaborative report. Helena, Mont: Montana Dept. of Public Health and Human Services, 2008.

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Lederman, Ruth I. Childhood cancer in Massachusetts, 1982-1986. Boston, Mass. (150 Tremont St., Boston 02111): Massachusettes Dept. of Public Health, 1989.

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C, Adamson Peter, National Cancer Policy Board (U.S.). Committee on Shortening the Time Line for New Cancer Treatments., Institute of Medicine (U.S.), National Research Council (U.S.), and National Academy of Sciences (U.S.), eds. Making better drugs for children with cancer. Washington, D.C: National Academies Press, 2005.

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Group, Children's Oncology. Cancer epidemiology in older adolescents and young adults 15 to 29 years of age: Including SEER incidence and survival, 1975-2000. Bethesda, MD]: U.S. Dept. of Health and Human Services, National Institutes of Health, National Cancer Institute, 2006.

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Campleman, Sharan L. Childhood cancer in California 1988 to 1999. Sacramento, CA: Cancer Surveillance Section, Cancer Control Branch, Division of Chronic Disease and Injury Control, California Dept. of Health Services, 2004.

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Verma, Mukesh, ed. Cancer Epidemiology. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-59745-416-2.

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Verma, Mukesh, ed. Cancer Epidemiology. Totowa, NJ: Humana Press, 2009. http://dx.doi.org/10.1007/978-1-60327-492-0.

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Mukesh, Verma, ed. Cancer epidemiology. New York: Humana, 2009.

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Book chapters on the topic "Cancer in children Epidemiology"

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Terracini, B. "Aetiology and Epidemiology." In Cancer in Children, 3–11. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-84722-6_1.

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Miller, R. W. "Aetiology and Epidemiology." In Cancer in Children, 3–8. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-96889-1_1.

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Riccabona, Georg. "Epidemiology." In Thyroid Cancer, 6–17. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71210-4_2.

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Pande, Mala, and Marsha L. Frazier. "Epidemiology." In Colorectal Cancer, 1–26. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118337929.ch1.

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Won, Young-Joo. "Epidemiology." In Pancreatic Cancer, 3–9. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-47181-4_1.

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Salvatore, Silvia, and Yvan Vandenplas. "Epidemiology." In Gastroesophageal Reflux in Children, 1–14. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-60678-1_1.

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Barra, Williams Fernandes, Samia Demachki, Geraldo Ishak, and Paulo Pimentel de Assumpção. "Epidemiology." In Diffuse Gastric Cancer, 5–14. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-95234-5_2.

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Dubois, A. "Epidemiology." In Exocrine Pancreatic Cancer, 1–10. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71178-7_1.

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Muir, C. S., and M. C. Gran. "Cancer Epidemiology." In Surgical Oncology, 31–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-72646-0_4.

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Boffetta, Paolo. "Cancer Epidemiology." In Encyclopedia of Cancer, 1–4. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_806-2.

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Conference papers on the topic "Cancer in children Epidemiology"

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Omaki, E., W. Shields, E. McDonald, P. Delgado, R. Stefanos, B. Solomon, and A. Gielen. "0074 Epidemiology of falls in young children." In Injury and Violence Prevention for a Changing World: From Local to Global: SAVIR 2021 Conference Abstracts. BMJ Publishing Group Ltd, 2021. http://dx.doi.org/10.1136/injuryprev-2021-savir.51.

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Angelova, Sirma, Teodora Targova, Vladimir Panov, Dimitrichka Bliznakova, and Radosveta Andreeva. "Epidemiology of Tooth Decay in Children with Pyelonephritis." In The 5th Virtual Multidisciplinary Conference. Publishing Society, 2017. http://dx.doi.org/10.18638/quaesti.2017.5.1.360.

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Omar Hasan Kasule, SR. "Epidemiology of breast cancer in Malaysia." In Asian Breast Diseases Association (ABDA) 3rd Teaching Course: Advances in the Management of Breast Diseases. Kuantan, Malaysia: Asian Breast Diseases Association, 2005. http://dx.doi.org/10.2349/biij.1.1.e6-14.

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Schüz, J. "OCCUPATIONAL CANCER EPIDEMIOLOGY: OPPORTUNITIES AND CHALLENGES." In The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-621-623.

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Abstract. It is estimated that exposure to carcinogens at the workplace are responsible for around 3-5% of the total cancer burden in Europe; this figure may be even somewhat higher for the Russian Federation due to its large industrial workforce. As most occupational exposures are modifiable risk factors, occupational hygiene and safety has a major role in primary cancer prevention. While both experimental and epidemiological studies contribute to the identification of carcinogens, ultimately the epidemiology is needed for determining the risk of individuals and populations under real-life exposure conditions and co-exposures. Occupational cohort studies are a very strong methodology to obtain this scientific evidence and with the conduct of a large-scale study of chrysotile workers in Asbest, Sverdlovsk Oblast, a blueprint has been developed on how to conduct further studies of that type in other industries. This will inform the elimination strategy of occupational cancer in the Russian Federation as well as our understanding of occupational cancers on global scale.
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Lane, Crystal, Amy Kennedy, Michelle Brotzman, Amy Miller, Gabriel Lai, Muin Khoury, and Daniela Seminara. "Abstract LB-195: Supporting cancer epidemiology research through cohort registration: NCI's cancer epidemiology cohort descriptive database." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-lb-195.

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McDougall, Catherine M., Robert Adderley, David F. Wensley, and Michael D. Seear. "Long-Term Ventilation In Children: Epidemiology Of An Epidemic." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a6276.

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Shushkevich, A., and A. Petrasheuski. "455 Epidemiology of endometrium cancer in Belarus." In IGCS 2020 Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2020. http://dx.doi.org/10.1136/ijgc-2020-igcs.395.

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Schildkraut, Joellen M. "Abstract IA31: Molecular epidemiology of ovarian cancer." In Abstracts: Eighth AACR Conference on The Science of Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; November 13-16, 2015; Atlanta, Georgia. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7755.disp15-ia31.

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Sitorus, Rico Januar, Chairil Anwar, and Novatria. "Epidemiology of Pediculosis Capitis of Foster Children in Orphanages Palembang, Indonesia." In 2nd Sriwijaya International Conference of Public Health (SICPH 2019). Paris, France: Atlantis Press, 2020. http://dx.doi.org/10.2991/ahsr.k.200612.028.

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Jerbi, Amira, Imene Fodha, Meriam Ben Hmida, Haifa Bennour, Imene Ataoui, Mouna Ben Hadj Fredj, and Abdelhalim Trabelsi. "Molecular epidemiology of respiratory syncytial virus in hospitalized children in Tunisia." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa1051.

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Reports on the topic "Cancer in children Epidemiology"

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Trock, Bruce J. Molecular Epidemiology of Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, January 2005. http://dx.doi.org/10.21236/ada439125.

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Neuhausen, Susan L. Genetic Epidemiology of Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, June 2005. http://dx.doi.org/10.21236/ada442276.

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Bowtell, David, Adele Green, Georgia Chenevix-Trench, Anna DeFazio, Dorota Gertig, David Purdie, Penelope Webb, and David Whiteman. Molecular Epidemiology of Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2005. http://dx.doi.org/10.21236/ada444073.

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Bowtell, David, Adele Green, Georgia Chenevix-Trench, Anna deFazio, and Dorota Gertig. Molecular Epidemiology of Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada409447.

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Neuhausen, Susan L. Genetic Epidemiology of Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, March 2006. http://dx.doi.org/10.21236/ada454886.

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Bowtell, David, Adele Green, Georgia Chenevix-Trench, Anna DeFazio, and Dorota Gertig. Molecular Epidemiology of Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2004. http://dx.doi.org/10.21236/ada430282.

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Neuhausen, Susan L. Genetic Epidemiology of Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, March 2007. http://dx.doi.org/10.21236/ada470273.

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Nazario, Cruz M. Breast Cancer Epidemiology in Puerto Rico. Fort Belvoir, VA: Defense Technical Information Center, June 2009. http://dx.doi.org/10.21236/ada512884.

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Nazario, Cruz M. Breast Cancer Epidemiology in Puerto Rico. Fort Belvoir, VA: Defense Technical Information Center, June 2012. http://dx.doi.org/10.21236/ada584895.

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Nazario, Cruz M. Breast Cancer Epidemiology in Puerto Rico. Fort Belvoir, VA: Defense Technical Information Center, June 2010. http://dx.doi.org/10.21236/ada584896.

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