Academic literature on the topic 'Cancer colorectal – Cytologie'
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Journal articles on the topic "Cancer colorectal – Cytologie"
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Lucha, Paul A., Romeo Ignacio, Dennis Rowley, and Michael Francis. "The Incidence of Positive Peritoneal Cytology in Colon Cancer: A Prospective Randomized Blinded Trial." American Surgeon 68, no. 11 (November 2002): 1018–21. http://dx.doi.org/10.1177/000313480206801117.
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Many investigators have attempted to explain the suspected increased incidence of port site metastasis in patients undergoing laparoscopic colorectal resections for cancer with animal models in which cancer is simulated by injection of a tumor slurry into the peritoneal cavity. This approach makes the basic assumption that all patients with colorectal malignancies have viable cancer cells freely circulating within the peritoneal cavity. Recent reports in open colorectal resections have conflicting results. Some suggest that the true incidence is negligible and related to advanced-stage cancers whereas others implicate a much higher incidence. We initiated a prospective blinded trial to establish the true incidence of malignant peritoneal cytology in colorectal cancer. One hundred eight consecutive colon resections underwent conventional peritoneal cytologic evaluation. The patients included those with inflammatory conditions of the colon as well as malignant disease. The cytopathologist was blinded as to the indications for surgery as well as the final pathology result. In only one case—stage IV rectal cancer with peritoneal carcinomatosis—was the cytologic specimen positive. Malignant cytology appears to be an infrequent occurrence and is restricted to advanced-stage cancer.
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Kobayashi, Hirotoshi, Kenjiro Kotake, Kenichi Sugihara, and Yoichi Ajioka. "Peritoneal lavage cytology in patients with curative resection for stage II and III colorectal cancer: A multi-institutional prospective study." Journal of Clinical Oncology 42, no. 3_suppl (January 20, 2024): 11. http://dx.doi.org/10.1200/jco.2024.42.3_suppl.11.
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11 Background: Although various prognostic factors in patients with colorectal cancer has been reported, the usefulness of intraoperative lavage cytology in patients with colorectal cancer is controversial. The aim of this study was to clarify the usefulness of intraoperative lavage cytology in patients with curative resection for pSage II-III colorectal cancer in a prospective multicenter study. Methods: The 20 member hospitals of the Japanese Society for the Cancer of the Colon and Rectum prospectively registered the patients diagnosed as stage II or III colorectal cancer preoperatively between 2013 and 2017. Among these patients, pStage II-III patients went through analysis. Lavage cytology was performed twice during surgery. The first procedure was performed right after laparotomy, and the second was performed right after specimen retrieval. The primary endpoint of this study was an effect of lavage cytology on 5-year relapse-free survival (RFS) in patients with pStage II-III colorectal cancer. The secondary endpoint was an effect of lavage cytology on 5-year overall survival (OS) and peritoneal recurrence in patients with pStage II-III colorectal cancer. Results: A total of 1378 patients were eligible and went through analysis. The number of patients with pStage II and III colorectal cancer were 670 and 708, respectively. Among 1378 patients, 54 (3.9%) had positive cytology. The median follow-up period of the entire cohort was 5.3 years. In pStage II patients, the 5-year RFS rate with positive and negative cytology was 61.1% and 81.6%, respectively (P = 0.023). The 5-year OS rate of pStage II patients with positive and negative cytology was 67.1% and 91.7%, respectively (P = 0.0083). However, there was no difference in RFS and OS between patients with positive and negative cytology in pStage III patients. Thirty-three patients had peritoneal recurrence. The peritoneal recurrence rate was 11.8% and 1.5% in pStage II patients with positive and negative lavage cytology, respectively (P = 0.032). That was 10.5% and 2.5% in pStage III patients with positive and negative lavage cytology, respectively (P = 0.022). In total, 11.1% of patients with positive lavage cytology had peritoneal recurrence in this cohort. Conclusions: The pStage II colorectal cancer patients with negative cytology had better RFS and OS compared to those with positive cytology. Peritoneal lavage cytology was useful in predicting peritoneal recurrence after curative resection for pStage II-III colorectal cancer. Clinical trial information: UMIN000026070 .
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Tatomirovic, Zeljka, Vesna Skuletic, Ivana Tufegdzic, Ljiljana Tomic, Jelena Dzambas, and Dino Tarabar. "The value of brush cytology and biopsy for the diagnosis of colorectal cancer." Vojnosanitetski pregled 74, no. 7 (2017): 659–65. http://dx.doi.org/10.2298/vsp160112115t.
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Background/Aim. Although it is well-known the high sensitivity of brush cytology for the diagnosis of colorectal adenocarcinoma, this kind of diagnostics is not routinely used, and for the past years it has even been declining. The purpose of this study was to evaluate the value of brush cytology for the diagnosis of colorectal carcinoma, by comparison the results of brush cytology and biopsy, and then the results of both diagnostic methods with the final patohistological diagnosis of colorectal resection. Methods. This retrospective study included 173 patients with brush cytology of colorectal region during colonoscopy. In 166 patients concomitant biopsy specimens were obtained, and in 116 of them resection of the intestine as well. A total of the 106 patients underwent to all three diagnostic procedures. Results. Out of 166 patients who went through both brush cytology and biopsy, the congruent diagnosis was made in 129 (77.7%) patients: in 109 (65.7%) adenocarcinoma was diagnosed, which was confirmed after the resection of the intestine in 75 of the patients, and in 14 (8.4%) benign lesion, so there was no need for resection of the intestine. In 6 (3.6%) of the patients, both cytology and biopsy were negative, but the resected specimen was malignant. In 10 of the patients with malignant cytology in whom biopsy was not done, resection of the intestine confirmed malignancy. The sensitivity of detecting malignancy by brush cytology and biopsy were 87.9% and 78.3%, respectively (but this difference was not statistically significant, p = 0.083). Both methods had specificity and positive predictive values 100%. Negative predictive values for cytology and biopsy were 50% and 37.8%, respectively. The accuracy of cytology and biopsy was 89.2% and 80.8%, respectively. The combination of the results of brush cytology and biopsy increased the sensitivity of preoperative diagnostics to 94.8% which was significantly higher than sensitivity of biopsy (p < 0.001), but not than sensitivity of cytology (p = 0.102). Conclusion. Brush cytology could be a routine method, along with biopsy, in the diagnosis of colorectal malignancy. Both methods have comparable both sensitivity and accuracy, and its combination increases sensitivity of preoperative diagnostics of colorectal adenocarcinoma, which gives opportunity to better estimation of further diagnostic and therapeutic approach.
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Bhasin, DeepakK, Arvind Rajwanshi, Rakesh Kochhar, and SatishK Mehta. "BRUSH CYTOLOGY FOR COLORECTAL CANCER." Lancet 333, no. 8647 (May 1989): 1133–34. http://dx.doi.org/10.1016/s0140-6736(89)92404-5.
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Banerjee, Anjan, and Matt Seymour. "Peritoneal cytology in colorectal cancer." Diseases of the Colon & Rectum 42, no. 5 (May 1999): 686–87. http://dx.doi.org/10.1007/bf02234153.
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Jacobi, Elizabeth M., Gene Landon, Russell R. Broaddus, and Sinchita Roy-Chowdhuri. "Evaluating Mismatch Repair/Microsatellite Instability Status Using Cytology Effusion Specimens to Determine Eligibility for Immunotherapy." Archives of Pathology & Laboratory Medicine 145, no. 1 (March 30, 2020): 46–54. http://dx.doi.org/10.5858/arpa.2019-0398-oa.
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Context.— The approval of pembrolizumab for treatment of patients with microsatellite instability-high (MSI-H) or mismatch repair–deficient (dMMR) advanced cancers has led to increased requests for MSI and/or MMR immunoperoxidase (IPOX) testing. Diagnoses for patients with advanced-stage cancer are frequently made from cytology specimens. Objective.— To investigate the feasibility of using cell block (CB) preparations of effusions for MMR IPOX evaluation. Design.— Surgical pathology cases of colorectal and endometrial carcinomas with known MMR/MSI status and matched effusions with available CBs were identified. Cell block sections were evaluated for adequacy and stained with MMR IPOX (MSH2, MSH6, MLH1, and PMS2). The CBs were reviewed, the number of tumor cells quantified, and MMR IPOX was interpreted as retained, lost, suboptimal, or noncontributory. Results.— We identified 748 cases with MMR/MSI testing on surgical specimens having matched effusions. Of these, 131 cases (17.5%) had an available CB and 53 were deemed adequate for MMR IPOX staining. MMR IPOX results between effusion CBs and surgical pathology specimens were concordant in 45 of 53 (85%), inconclusive in 6 of 53 (11%), and discordant in 2 of 53 (4%) cases. Conclusions.— There was high concordance of MMR IPOX testing between cytologic and surgical specimens, with no false-positive and 2 false-negative CB results. Limited tumor cells, staining in cells indefinite as tumor, tumor staining heterogeneity, and lack of internal control staining were problematic in some cases. Our findings indicate that cytologic effusion specimens may be suitable substrates for MMR IPOX biomarker testing; however, inconclusive cases need to be interpreted with caution.
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Vilella, Angels, Magdalena Garcia-Bonafe, Carlos Dolz, Hernan Andreu, Alvaro Brotons, and Javier Ibarra. "Cytologic Study for Endoscopic Diagnosis of Colorectal Cancer." Gastrointestinal Endoscopy 61, no. 5 (April 2005): AB266. http://dx.doi.org/10.1016/s0016-5107(05)01395-7.
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Zhang, Min, Lin Li, Ping Liu, and C. D’Arcy J. Holman. "Green tea for the prevention of cancer: evidence of field epidemiology." Functional Foods in Health and Disease 2, no. 10 (October 15, 2012): 339. http://dx.doi.org/10.31989/ffhd.v2i10.79.
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Background: Tea is derived from the leaf of Camellia sinensis, a natural beverage widely consumed around the world. Geological and botanical evidence suggests that the tea plant originated from China. Varying methods of processing tea leaves lead to green tea, black tea, or Oolong tea, which differ in their concentrations of polyphenols. Green tea polyphenols appear to have anti-tumorigenic properties, and form 30-40% of the dry weight of green tea compared with only 3-10% of black tea. Numerous studies in multiple animal models and different cancer cell lines have demonstrated the anti-tumorigenesis by green tea polyphenols. Despite the consistency of laboratory results, evidence of this effect occuring in humans has been inconclusive to date.Objective: To investigate if green tea consumption was associated with longer survival rates in ovarian cancer patients, and a lower risk of ovarian, breast, and colorectal cancer, in addition to adult leukemiaMethods: We have conducted one prospective cohort study in ovarian cancer patients, and five case-control studies in ovarian, breast, and colorectal cancers, and leukemia over the past decade. Tea consumption was measured using a structured questionnaire by face-to-face interviews. The validity and reliability of the questionnaire was assessed in a preliminary study, and then evaluated by a test–retest. Cox proportional hazards regression models were used to obtain hazard ratios(HRs), 95% confidence intervals(95% CIs), and were adjusted for age at diagnosis, locality, body mass index(BMI), parity, International Federation of Gynecology and Obstetrics (IFGO) stage, histologic grade of differentiation, cytology of ascites, residual tumour, and chemotherapeutic status. Odds ratios(ORs) and 95% CIs were obtained using logistic regression analyses, which accounted for demographic, lifestyle, hormonal and family cancer factors, and potential confounders. Results: Higher green tea consumption was consistently observed as being associated with a lower risk of mortality due to ovarian cancer, and a decreased risk of ovarian, breast, and colorectal cancers, and adult leukemia occurrences in our observational studies. The adjusted HR and 95% CI for case mortality from ovarian cancer was 0.40(0.18-0.90) in the patients who consumed green tea at the highest level compared with non-tea drinkers. Compared with never or seldom tea drinkers, the adjusted ORs ranged from 0.07 to 0.61 for ovarian, breast, and colorectal cancers, and adult leukemia in those who consumed green tea at the highest level. Significant inverse dose-response relationships were also observed for quantity, duration, and frequency of green tea consumed.Conclusion: We concluded that regular consumption of green tea enhanced survival of ovarian cancer, and decreased risks of ovarian, breast, and colorectal cancers, and adult leukemia. Evidence from our observational studies supported the protective effect of green tea against cancers, and this evidence will provide a knowledge platform from which to launch interventional studies for cancer prevention in the next stage.Key words: Green tea, nutrition epidemiology, case-control studies, cohort studies, risk factor, cancer survival, breast cancer, colorectal cancer, adult leukemia, ovarian cancer
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Alyautdina, O. S., and O. V. Sinicina. "Intraepithelial colorectal lesions in women with cervical infection with human papillomavirus." Clinical Medicine (Russian Journal) 96, no. 5 (October 12, 2018): 459–62. http://dx.doi.org/10.18821/0023-2149-2018-96-5-459-462.
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Human papillomavirus (HPV)-induced cervical cancer and colorectal cancer are closely related. Women with cervical HPV infection have more than 3 times the high risk of anal infection. Some studies indicate a persistent relationship between colorectal cancer caused by HPV infection and a similar genotype of cervical cancer. In our research, using the method of liquid cytology, a comparison of colorectal HPV lesion in patients with dysplasia of the cervix in history and a control group without pathology of the cervix was carried out. The cytological study was performed using the method of liquid cytology BDShurePath using the automated scanning system BDFocalPoint. Detection of HPV genotypes of high oncogenic risk (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68) was carried out by hybrid capture (HPVdigene-test hybrid capture ll).The results of our studies showed that 24% of patients at high risk in the cytological examination of scrapings from the rectum had an intraepithelial lesion of the rectal epithelium, most likely associated with HPV infection. In the control group, these changes were not observed. The results show that HPV-associated pathology of the cervix is a risk factor for intraepithelial damage to the rectum. Such patients are in a group at high risk of developing colorectal cancer and should undergo a regular appropriate examination.
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FURUYAMA, Nobuaki. "Direct vision brushing cytology of colorectal cancer." Journal of the Japanese Society of Clinical Cytology 24, no. 2 (1985): 157–64. http://dx.doi.org/10.5795/jjscc.24.157.
Full textDissertations / Theses on the topic "Cancer colorectal – Cytologie"
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Pasquier, Nicolas. "Integrin-mediated regulation of apicobasal polarity, cell states and cancer progression." Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASL048.
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Les intégrines sont des protéines régulant l'adhésion, la migration et l'architecture cellulaires, jouant un rôle tant dans le développement des tissus sains que dans la progression cancéreuse. Bien que les intégrines aient été largement étudiées dans divers modèles biologiques, la manière dont leur disponibilité agit sur la polarité apicobasale, la migration et la capacitation cellulaires n'est pas entièrement connue à ce jour.Ici, nous étudions le rôle des intégrines, et principalement de l'intégrine-β1, sur l'établissement de la polarité apicobasale ainsi que sur la migration cellulaire dans des modèles cancéreux. Nous décryptons également leur action sur l'établissement de l'identité cellulaire en étudiant leur rôle dans la capacitation des cellules souches pluripotentes induites humaines (hiPSCs).Les résultats de cette thèse permettent d'identifier une nouvelle une boucle de recyclage de l'intégrine-β1, dépendante de SorLA, HER2 et HER3, permettant aux cellules de cancer du côlon de percevoir la matrice et d'orienter leur polarité apicobasale. Nous approfondissons également la compréhension de la migration de cellules cancéreuses sur la matrice extra-cellulaire en identifiant deux compositions matricielles (collagène + laminine et laminine + ténascine C) permettant aux cellules cancéreuses d'ostéosarcome et aux fibroblastes de migrer indépendamment de la rigidité du substrat grâce à une augmentation du nombre de points d'ancrage moléculaires impliquant l'intégrine-β1. Nous investiguons également le rôle de l'intégrine-β1 dans le processus de capacitation des cellules souches et montrons que l'inhibition de l'intégrine-β1 maintient un phénotype similaire à l'état naïf chez les hiPSCs.Ensemble, ces données soulignent l'importance des intégrines, et principalement de l'intégrine-β1, dans de nombreux processus cellulaires parmi les modèles, expliquant ainsi son importance dans l'adhésion cellulaire, l'architecture des cellules cancéreuses ainsi que dans l'établissement de l'identité cellulaireIntegrins regulate cell adhesion, migration and architecture which play a role both in development of healthy tissues and disease. While integrins have been widely studied amongst models, the way their availability acts on polarity, spreading and cell capacitation is not fully understood.Here we investigate the role of integrins, and mainly integrin-β1, on polarity establishment as well as cell spreading in cancer models. We also decipher their action on cell states by studying their role in human induced pluripotent stem cells (hiPSCs) capacitation.This thesis reveals a newly described SorLA, HER2 and HER3-dependent Integrin-β1 recycling loop, allowing colon cancer cells to sense the matrix and orient their polarity accordingly. We also go deeper in cancer cell spreading on matrix, by identifying two matrix compositions (collagen + laminin and laminin + tenascin C) allowing osteosarcoma cancer cells and fibroblasts to spread in a stiffness-independent fashion through an increased amount of integrin-β1-positive molecular clutches. We also investigate the role of Integrin-β1 on the capacitation process of stem cells and show that inhibition of integrin-β1 maintains a naïve-like phenotype in hiPSCs.Taken together, these data highlight the importance of integrins, and mainly integrin-β1, in many cell processes amongst models, thus explaining its key role in cell adhesion, cancer cell architecture and cell state establishment
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Walter, Alexander. "A comparison of continuum and cell-based models of colorectal cancer." Thesis, University of Nottingham, 2009. http://eprints.nottingham.ac.uk/10763/.
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Colorectal cancer is thought to originate in the epithelial cells that line the colorectal crypt and, in most cases, is associated with a mutation in Wnt-signalling pathway. These mutations cause cells to alter their proliferative behaviour, make their cytoskeleton less deformable and increase their levels of cell-cell and cell-substrate adhesion. In this thesis we develop three different types of models for the proliferation and movement of epithelial cells in a colorectal crypt. We use these models to investigate how changing the cell adhesion, cytoskeleton and proliferation properties of mutant cells affects their ability to establish a mutant population within the crypt. First we develop a continuum model of two cell populations, normal and mutant, using a spatially-varying source term to model Wnt-dependent proliferation and using Darcy's law to describe cell movement down pressure gradients. We distinguish between mutant cells and normal cells by assuming the former have a spatially independent source term, representing proliferation, and a different viscosity to normal cells, to model changes in their cytoskeleton and levels of adhesion. The model is solved analytically by an asymptotic expansion of the variables and numerically using a collocation method. The results show that the ability of mutant cells to remain in the crypt depends on the position of the initial mutation and their viscosity: the further up the crypt a cell suffers a mutation the more rigid and adhesive the cell must be for a mutation to persist. We then consider a discrete cell-centre model based on the work of Meineke et al. (2001). Cell-cell interaction forces are modelled by springs and are balanced by a viscous drag term. Adaptations to Meineke et al. (2001) include unpinning of stem cells from the bottom of the crypt, dependence of cell-drag on cell size, dependence of cell-cell interaction forces on their area of contact and the inclusion of mutant cells. Using agile software engineering techniques, the software environment, CHASTE, is developed and used to solve the model numerically and to reproduce experimental findings such as crypt homoeostasis and monoclonality. The results again reveal that increasing the drag on the mutant cells increases the likelihood of a mutant population establishing itself within the crypt. The third approach is a discrete cell-vertex model. The model decouples cell-cell adhesion forces from cell deformation forces and movement is determined by a free-energy gradient balanced by a viscous drag term. Numerical simulations show that the model can generate similar results to the cell-centre model, and reveal that increased cell-cell adhesion of the mutant cells increases the likelihood of the mutant population invading the crypt. Finally the three models are compared in terms of their suitability for modelling epithelial tissue.
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Mayo, de las Casas Clara de la Caridad. "Control de la diferenciación celular in vitro en células HT-29 de cáncer colorectal." Doctoral thesis, Universitat Pompeu Fabra, 2005. http://hdl.handle.net/10803/7081.
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La línea celular HT-29 M6 es una línea tumoral humana derivada de adenocarcinoma de colon, con capacidad de diferenciación in vitro hacia un fenotipo mucosecretor, obtenida por selección con 10-7 M y 10-6 M de metotrexato, en tratamientos sucesivos, de la línea parental indiferenciada HT-29 (Lesuffleur T, et al, 1990). Nosotros utilizamos esta línea celular como modelo para estudiar el proceso de diferenciación in vitro que ocurre de manera espontánea durante el crecimiento hacia confluencia. Los resultados que presentamos en este trabajo aportan evidencias sólidas acerca del papel del calcio extracelular como modulador no sólo de la epitelialización, sino también del ciclo celular y de la expresión génica durante la diferenciación in vitro. Aunque puede existir más de un mecanismo por el que el calcio extracelular sea responsable de los efectos observados, los resultados obtenidos son consistentes con el requerimiento de contactos de adhesión para la diferenciación epitelial. Además, los resultados sugieren que reguladores del ciclo celular, concretamente ciclina D1 y p27, desempeñan un papel determinante en el control del programa de expresión génica durante la diferenciación. Este resultado es muy relevante ya que: (1) su función parece tener lugar de manera general sobre el programa de expresión génica, y (2) al estar estas proteínas implicadas en la progresión tumoral, su mecanismo de acción emerge como una diana para manipular el fenotipo de diferenciación celular y con ello la tumorigenicidad. Por otro lado, hemos descubierto que parte del proceso de diferenciación in vitro es independiente de la formación de contactos de adhesión y de la epitelialización, concretamente niveles basales de expresión génica asociada a diferenciación y la producción de vesículas de moco. Asimismo, en condiciones de no adherencia celular, las células no adquieren capacidad invasiva, lo cual nos está indicando que la desdiferenciación celular observada en tumores y la adquisición de capacidad invasiva podría tener lugar por vías separadas. Finalmente, hemos obtenido evidencias preliminares acerca de la existencia de una vía de regulación de APC sobre p21CIP1 cuya inactivación podría estar relacionada con la reversibilidad del programa de diferenciación in vitro y con su incapacidad para llevar a término un programa de diferenciación terminal.
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"Transient cell cycle arrest and autophagy induction in colorectal cancer HT29 cell line by sodium 5,6-benzylidene-L-ascorbate." 2008. http://library.cuhk.edu.hk/record=b5893623.
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Cheung, Wing Ki.Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.
Includes bibliographical references (leaves 100-112).
Abstracts in English and Chinese.
Acknowledgments
Abbreviations
Abstract 一 English --- p.i
- Chinese --- p.iii
Chapter Chapter 1 --- General Introduction
Chapter 1.1. --- Colon Cancer
Chapter 1.1.1. --- Colon cancer statistic in Hong Kong --- p.1
Chapter 1.1.2. --- Development of Colon cancer --- p.1
Chapter 1.1.3. --- Treatment --- p.2
Chapter 1.2. --- Chemistry of ascorbates
Chapter 1.2.1. --- Sodium-L-ascorbate --- p.3
Chapter 1.2.2. --- "Sodium 5,6-benazylidene-L-ascorbate" --- p.4
Chapter 1.3. --- "Reactive oxygen species and reactive nitrogen species, and their biological consequences" --- p.5
Chapter 1.4. --- Cell cycle --- p.7
Chapter 1.5. --- Autophagy --- p.8
Chapter 1.6. --- Human colon cancer HT29 cells for anti-tumor study --- p.9
Chapter 1.7 --- Aim of study --- p.10
Chapter Chapter 2 --- Comparative studies of cytotoxicity of SAA and SBA in short term treatment
Chapter 2.1. --- Introduction --- p.11
Chapter 2.2. --- Materials and Methods --- p.14
Chapter 2.3. --- Results --- p.17
Chapter 2.4. --- Discussion --- p.26
Chapter Chapter 3 --- Comparative studies of SAA and SBA in oxidative stress induction and their corresponding ROS inhibitors
Chapter 3.1. --- Introduction --- p.28
Chapter 3.2. --- Materials and Methods --- p.31
Chapter 3.3. --- Results --- p.35
Chapter 3.4. --- Discussion --- p.42
Chapter Chapter 4 --- "Effects of SAA and SBA treatments on cell cycle regulatory proteins and the induction of transient cell cycle arrests in Gl, S and G2 phases Cell Cycle"
Chapter 4.1. --- Introduction --- p.45
Chapter 4.2. --- Materials and Methods --- p.49
Chapter 4.3. --- Results --- p.53
Chapter 4.4. --- Discussion --- p.69
Chapter Chapter 5 --- Autophagy induction during SBA treatment and autophagy inhibition during SAA treatment
Chapter 5.1. --- Introduction --- p.72
Chapter 5.2. --- Materials and Methods --- p.74
Chapter 5.3. --- Results --- p.77
Chapter 5.4. --- Discussion --- p.91
Chapter Chapter 6 --- General Discussion --- p.93
References --- p.100
Conference papers on the topic "Cancer colorectal – Cytologie"
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Ueda, Koji, Takeshi Yamada, Michihiro Koizumi, Seiichi Shinji, Akihisa Matsuda, Ryo Ohta, Goro Takahashi, et al. "Abstract 6470: Possibility of digital cytology of intraoperative ascites and lavage fluid in patients with colorectal cancer." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-6470.
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