Journal articles: 'Calcium phosphate bioceramic'

1

Pattanayak, Deepak K., B. T. Rao, and T. R. Rama Mohan. "Calcium phosphate bioceramics and bioceramic composites." Journal of Sol-Gel Science and Technology 59, no. 3 (November 4, 2010): 432–47. http://dx.doi.org/10.1007/s10971-010-2354-y.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

FINISIE, MELLATIE R., ATCHE JOSUÉ, VALFREDO T. FÁVERE, and MAURO C. M. LARANJEIRA. "Synthesis of calcium-phosphate and chitosan bioceramics for bone regeneration." Anais da Academia Brasileira de Ciências 73, no. 4 (December 2001): 525–32. http://dx.doi.org/10.1590/s0001-37652001000400006.

Full text

Abstract:

Bioceramic composites were obtained from chitosan and hydroxyapatite pastes synthesized at physiological temperature according to two different syntheses approaches. Usual analytical techniques (X-ray diffraction analysis, Fourier transformed infrared spectroscopy, Thermo gravimetric analysis, Scanning electron microscopy, X-ray dispersive energy analysis and Porosimetry) were employed to characterize the resulting material. The aim of this investigation was to study the bioceramic properties of the pastes with non-decaying behavior from chitosan-hydroxyapatite composites. Chitosan, which also forms a water-insoluble gel in the presence of calcium ions, and has been reported to have pharmacologically beneficial effects on osteoconductivity, was added to the solid phase of the hydroxyapatite powder. The properties exhibited by the chitosan-hydroxyapatite composites were characteristic of bioceramics applied as bone substitutes. Hydroxyapatite contents ranging from 85 to 98% (w/w) resulted in suitable bioceramic composites for bone regeneration, since they showed a non-decaying behavior, good mechanical properties and suitable pore sizes.

APA, Harvard, Vancouver, ISO, and other styles

3

LIANG, H., Y. HUANG, F. HE, H. F. DING, and Y. Z. WAN. "ENHANCED CALCIUM PHOSPHATE PRECIPITATION ON THE SURFACE OF Mg-ION-IMPLANTED ZrO2 BIOCERAMIC." Surface Review and Letters 14, no. 01 (February 2007): 71–77. http://dx.doi.org/10.1142/s0218625x07009086.

Full text

Abstract:

Modification of bioceramics by ion implantation of magnesium ( Mg ) is of interest as Mg is the fourth abundant cation in the human body. In this work, magnesium was ion-implanted into a ZrO 2 based bioceramic stabilized with Y 2 O 3 and Al 2 O 3. Both Mg -implanted and unimplanted samples were soaked in a simulated body fluid (SBF) for a period of time. The deposits on the surface of various samples were characterized with scanning electron microscope (SEM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR). We find that the Mg -implanted ZrO 2 shows better bioactivity than the plain bioceramic. These results indicate that Mg -implantation can improve the bioactivity of the ZrO 2 based bioceramic. Mechanisms governing the improvement are discussed in this paper.

APA, Harvard, Vancouver, ISO, and other styles

4

Gittings, J. P., I. G. Turner, and A. W. Miles. "Calcium Phosphate Open Porous Scaffold Bioceramics." Key Engineering Materials 284-286 (April 2005): 349–52. http://dx.doi.org/10.4028/www.scientific.net/kem.284-286.349.

Full text

Abstract:

Calcium phosphate (CaP) ceramics possessing an interconnecting porosity network in the appropriate size range for vascularisation offer the possibility of providing a structural matrix for replacement of diseased or damaged bone. Such bioceramics must possess sufficient mechanical strength to avoid failure whilst offering a bioactive surface for bone regeneration. The objective of the current study was to produce a hydroxyapatite/tricalcium phosphate (HA/TCP) bioceramic that imitated the orientated trabecular structure found in cancellous bone. The structure-property relationship of these bioceramics was then analysed. It was hypothesised that the mechanical properties would be linked to the shape of the pore structure due to the orientation of the open porous scaffolds (OPS) produced. OPS bioceramics possessed an interconnected macroporosity network of 40-70% by volume with bending strengths of 0.30MPa ± 0.01MPa and apparent densities of 0.35g/cm3 ± 0.05g/cm3. Typically, pore sizes in the range of 150-300µm were produced. The fabrication of CaP OPS resulted in a wide range of macroporosity in the correct size range for osseointegration to occur. Elongating the pore structure did not affect the total porosity of the bioceramics. Strengths were low due to microcrack formation on sintering and not due to the shape of the pores present in the scaffold as initially hypothesised.

APA, Harvard, Vancouver, ISO, and other styles

5

Albuquerque, J. S. V., I. W. L. Franca, G. F. Silva, A. L. O. Ferreira, and R. E. F. Q. Nogueira. "Macroporous Calcium Phosphate Bioceramics as Drug Release Agents: A Kinetics Study of Ampicillin Release." Key Engineering Materials 396-398 (October 2008): 675–78. http://dx.doi.org/10.4028/www.scientific.net/kem.396-398.675.

Full text

Abstract:

Semi-synthetic beta-lactam antibiotics are the most important class of antibacterial agents. Their use in veterinary and human medicine is in continuous expansion. Calcium phosphate bioceramics have been used in medicine and dentistry for nearly 30 years. Calcium phosphate ceramics (CPC) are nowadays being widely used as drug delivery systems because of their desirable properties such as biocompatibility, bioresorbability, controlled release etc. In recent years In this work, kinetic models to describe ampicillin adsorption from CPC were investigated. Calcium phosphate bioceramic are analogous to the mineral component of bones, its properties make it suitable for implant materials and delivery agents of drugs

APA, Harvard, Vancouver, ISO, and other styles

6

Hussain, Wafaa A., Entessar H. A. Al-Mosawe, Mukhlis M. Ismail, and Luay H. Alwan. "Porous Biphasic Calcium Phosphate for Biomedical Application." Journal of Biomimetics, Biomaterials and Biomedical Engineering 49 (February 2021): 101–10. http://dx.doi.org/10.4028/www.scientific.net/jbbbe.49.101.

Full text

Abstract:

Excellent osteoconductivity and resorbability achieved when porous bioceramics have highsurface area that providing fast bone ingrowth. Porous samples were fabricated by using biphasic calcium phosphate BCP (achieved from HA heat treated at 850 oC) with 10 and 20 wt% of ovalbumin binder powder and mixture of carrot fibers and ovalbumin powders (1:1) then dried at 60oC and fired at 1300 oC. Structural, physical and mechanical properties of the prepared porous bioceramic were determined involved X-ray diffraction, Fourier transform infrared spectroscopy FTIR, apparent porosity, water absorption, apparent solid density and compressive strength. The results of X-ray and FTIR showed that the heat treatment of HA was succeeded in forming biphasic calcium phosphate. The apparent porosity values increased with increasing of the binder and carrot fibers content and the growths density of bacteria on bioceramics are less than natural bone. The effect of pathogenic bacteria (Pseudomonas & Staphylococcus) that cause pollution on porous calcium phosphate and natural bone (Albino mice) has been studied.

APA, Harvard, Vancouver, ISO, and other styles

7

Tavoni, Marta, Massimiliano Dapporto, Anna Tampieri, and Simone Sprio. "Bioactive Calcium Phosphate-Based Composites for Bone Regeneration." Journal of Composites Science 5, no. 9 (August 27, 2021): 227. http://dx.doi.org/10.3390/jcs5090227.

Full text

Abstract:

Calcium phosphates (CaPs) are widely accepted biomaterials able to promote the regeneration of bone tissue. However, the regeneration of critical-sized bone defects has been considered challenging, and the development of bioceramics exhibiting enhanced bioactivity, bioresorbability and mechanical performance is highly demanded. In this respect, the tuning of their chemical composition, crystal size and morphology have been the matter of intense research in the last decades, including the preparation of composites. The development of effective bioceramic composite scaffolds relies on effective manufacturing techniques able to control the final multi-scale porosity of the devices, relevant to ensure osteointegration and bio-competent mechanical performance. In this context, the present work provides an overview about the reported strategies to develop and optimize bioceramics, while also highlighting future perspectives in the development of bioactive ceramic composites for bone tissue regeneration.

APA, Harvard, Vancouver, ISO, and other styles

8

Zheng, Min, Ding Fan, Jian Bin Zhang, and Xiu Kun Li. "Effect of Ceria Additive on Microstructure and Properties of Laser-Cladded Bioceramic Coating." Key Engineering Materials 434-435 (March 2010): 586–89. http://dx.doi.org/10.4028/www.scientific.net/kem.434-435.586.

Full text

Abstract:

The calcium phosphate bioceramic coating was fabricated on titanium alloy (Ti-6Al-4V) substrate by a 5kW continuous transverse flow CO2 laser. Due to the peculiar role of rare earth oxide in laser cladding, the effect of ceria additive on the microstructure and properties of laser-cladded bioceramic coating was investigated by means of scanning electron microscope (SEM), X-ray diffraction (XRD), microhardness and corrosion resistance testing. The results indicate that the appearance of rare earth oxide ceria in the precursor powders has an impact on the microstructure and properties of the laser-cladded bioceramic coating. Calcium phosphate bioceramic such as hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) are synthesized on the top surface of laser-cladded specimens. And the addition of rare earth oxide ceria in pre-placed powders has an influence on the formation of calcium phosphate bioceramic phases. Furthermore, it reveals that the laser-cladded bioceramic coating of ceria additive in pre-placed powders has more favorable microhardness and corrosion resistance compared with the coating without rare earth oxide.

APA, Harvard, Vancouver, ISO, and other styles

9

Hesaraki, Saeed, A. Zamani, and M. Hafezi. "Montmorillonite-Added Calcium Phosphate Bioceramic Foams." Key Engineering Materials 361-363 (November 2007): 111–14. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.111.

Full text

Abstract:

The present work was performed to improve the mechanical strength of porous calcium phosphate blocks by adding a little amount of montmorillonite mineral to the calcium phosphate composition. 3.5 wt % of the montmorillonite mineral was added to the slurry of precipitated hydroxyapatite and the porosity was produced by infiltration of a polymer template. After the firing process (1200 oC), the compressive strength, phase composition, morphology and dissolution behavior of the porous bodies were evaluated by appropriate techniques. It was found that the additive improved the mechanical strength but decreased the dissolution rate of the porous calcium phosphate body. Also the final composition of the porous block (i.e. hydroxyapatite, HA, and β- tricalcium phosphate, β-TCP) was not influenced through the presence of the additive. It is suggested that the montmorillonite mineral can improve the sintering performance of the HA and β- TCP.

APA, Harvard, Vancouver, ISO, and other styles

10

Jung, Yoona, Jooseong Kim, Sukyoung Kim, Shin hye Chung, and Jinhong Wie. "Development of Cellular Signaling Pathways by Bioceramic Heat Treatment (Sintering) in Osteoblast Cells." Biomedicines 11, no. 3 (March 5, 2023): 785. http://dx.doi.org/10.3390/biomedicines11030785.

Full text

Abstract:

Bioceramics are calcium-phosphate-based materials used in medical and dental implants for replacing or repairing damaged bone tissues; however, the effect of bioceramic sintering on the intracellular signaling pathways remains unknown. In order to address this, we analyzed the impact of sintering on the cell signaling pathways of osteoblast cells using sintered and non-sintered hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP). X-ray diffraction indicated that only the morphology of HA was affected by sintering; however, the sintered bioceramics were found to have elevated the calcium concentrations in relation to the non-sintered variants. Both bioceramics inhibited the JNK signaling pathway; the sintered HA exhibited half the value of the non-sintered variant, while the sintered β-TCP rarely expressed a p-JNK value. The total Src and Raptor protein concentrations were unaffected by the sintering, while the p-Src concentrations were decreased. The p-EGFR signaling pathway was regulated by the non-sintered bioceramics, while the p-p38 concentrations were reduced by both the sintered β-TCP and HA. All of the bioceramics attenuated the total AKT concentrations, particularly the non-sintered HA, and the AKT phosphorylation concentration, except for the non-sintered β-TCP. Thus, the sintering of bioceramics affects several intracellular signaling pathways. These findings may elucidate the bioceramic function and expand their application scope as novel substrates in clinical applications.

APA, Harvard, Vancouver, ISO, and other styles

11

He, Fupo, Ye Tian, Xibo Fang, Yubin Xu, and Jiandong Ye. "Porous calcium phosphate composite bioceramic beads." Ceramics International 44, no. 11 (August 2018): 13430–33. http://dx.doi.org/10.1016/j.ceramint.2018.04.109.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Sader, Marcia, Denisar Ismério, Mônica C. Andrade, Gloria D. Soares, Ivan N. Bastos, and Gustavo M. Platt. "Characterization and Dissolution Dynamics of Tricalcium Phosphates in Acidified Solution." Journal of Biomimetics, Biomaterials and Tissue Engineering 18 (December 2013): 61–71. http://dx.doi.org/10.4028/www.scientific.net/jbbte.18.61.

Full text

Abstract:

Bioceramics used in biomedical applications must exhibit specific behaviors. In scaffolds, for instance, the degradability of bioceramics is important to allow the cell ingrowth. Therefore, the dissolution of calcium phosphates increases the ionic concentrations around the interface implant–bone, favoring a more rapid bone apposition to the graft surface. The dissolution takes place under static or dynamic conditions, but the latter is usually not performed under rigorous hydrodynamic control. In the present work, two bioceramics, β-tricalcium phosphate and β-tricalcium phosphate substituted by magnesium, were produced by pressing and sintering to form disks. They were characterized by XRD, Raman, ICP, SEM, AFM and photometric test. The influence of chemical composition in the dissolution test was conducted through strict control of the hydrodynamic conditions. The disks were rotating in a precise speed, in order to produce a dissolution under the well-controlled mass transfer. Subsequently, the calcium release was evaluated in a simulated infectious environment using pH equals to circa 4. Thus, it was possible to evaluate the fraction of dissolution related to mass transfer or surface reactions for a large rotation speed range. The magnesium added to the bioceramic inhibits the total dissolution when compared to pure tricalcium phosphate, probably related to more dense and less soluble ceramic. Moreover, the mass transfer affects relatively less the magnesium tricalcium phosphate than pure tricalcium phosphate.

APA, Harvard, Vancouver, ISO, and other styles

13

Mehdikhani, Behzad, and Bahman Mirhadi. "Densification and Hardness Behaviour of Nanocrystalline Hydroxyapatite/β-Tricalcium Phosphate Composite Powders." Journal of Biomimetics, Biomaterials and Tissue Engineering 14 (July 2012): 81–91. http://dx.doi.org/10.4028/www.scientific.net/jbbte.14.81.

Full text

Abstract:

In this study, dense, fine-grained biphasic calcium phosphate bioceramics were designed via sintering method. nanosize hydroxyapatite / β-tricalcium (HA/β-TCP) phosphate powders with average grain size of 80 nm were prepared by the wet chemical precipitation method with calcium nitrate and di-ammonium hydrogen phosphate as calcium and phosphorus precursors, respectively. The precipitation process employed was also found to be suitable for the production of sub-micrometre HA/β-TCP powder in situ. The sinterability of the nanosize powders, and the microstructure, mechanical strength of the prepared HA/β-TCP bioceramics were investigated. Bioceramic sample characterization was achieved by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), and density measurements. Powders compacted and sintered at 800, 900, 1000 and 1100°C showed an increase in relative density from 57% to 93%. The results revealed that the maximum hardness of 229 HVwas obtained for HA/β-TCP sintered at 1100°C.

APA, Harvard, Vancouver, ISO, and other styles

14

Sahin, Yesim Muge, Oguzhan Gunduz, Anton Ficai, Nazmi Ekren, Ali Tuna, Ahmet Talat Inan, and Faik Nüzhet Oktar. "Can European Sea Bass (Dicentrarchus labrax) Scale Be a Good Candidate for Nano-Bioceramics Production?" Key Engineering Materials 696 (May 2016): 60–65. http://dx.doi.org/10.4028/www.scientific.net/kem.696.60.

Full text

Abstract:

Bioceramics are commonly used biomaterials for orthopedic and dental applications. Among these bioceramics, hydroxyapatite (HA) and tricalcium phosphate (TCP) are of interest and are used in various biomedical applications. Production of bioceramics from natural materials such as bovine and sheep bones with calcination method, is possible. Lately, fish scales become an alternative biological source for bioceramic production. The present study proposes an approach to obtain HA bone-scaffolds from European Sea Bass (Dicentrarchus labrax) scales aiming to provide nano-biomaterials via calcination method. Untreated fish scales are obtained and are carefully cleaned from their meat and grease. They are washed with alkaline water several times and calcinated at 850°C for 4 hours. Energy Dispersive Spectroscopy (EDS), X-ray diffraction analysis, Scanning Electron Microscopy (SEM) studies are performed. Various calcium phosphate species (HA, TCP) are identified in the study. SEM images prove the presence of the nano-scale structures. This study indicates calcination as a simple way of nano-scale bioceramic production for drug delivery and tissue engineering applications. Being produced from wastes of a sustainable and cheap source, these bioceramics can be good candidates for future clinical applications.

APA, Harvard, Vancouver, ISO, and other styles

15

Tas, A. Cüneyt. "Combustion synthesis of calcium phosphate bioceramic powders." Journal of the European Ceramic Society 20, no. 14-15 (December 2000): 2389–94. http://dx.doi.org/10.1016/s0955-2219(00)00129-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Tikhonov, Andrey, and Valery Putlayev. "Synthesis and Thermal Behaviour of Calcium Alkyl Phosphates as Bioceramic Precursors." Ceramics 5, no. 3 (July 29, 2022): 362–71. http://dx.doi.org/10.3390/ceramics5030028.

Full text

Abstract:

Powders of alkyl phosphoric acids and calcium alkyl phosphates with various alkyl chains (butyl, octyl, and dodecyl) have been synthesized. The resulting powders were characterized by X-ray phase analysis, electron microscopy, and thermal analysis. It was shown that the calcium alkyl phosphates correspond to the composition of acid salts of calcium alkyl phosphates Ca(RPO4H)2, data on which are not presented in the literature. The thermal behaviour of calcium alkyl phosphates can be described as a complex phase transformation into biphasic calcium phosphate mixture (of Ca2P2O7 and Ca3(PO4)2) with the increase of the Ca to P ratio in comparison to initial materials. The powders thermally treated in the range of 400–600 °C could be recommended as single precursors of biphasic bioceramics.

APA, Harvard, Vancouver, ISO, and other styles

17

Yeung, H. Y., Ling Qin, K. M. Lee, K. S. Leung, and Jack C. Y. Cheng. "Objective Quantification of Porous Structure in Orthopaedic Biomaterial Implants Using Micro Computed Tomography." Key Engineering Materials 334-335 (March 2007): 1205–8. http://dx.doi.org/10.4028/www.scientific.net/kem.334-335.1205.

Full text

Abstract:

Porous calcium phosphate ceramics have been widely investigated in orthopaedic surgery as bone extensor. Attention has been given to manufacturing of a porous bioceramic that mimics the trabecular bone structure for proper bone regeneration and integration. Although different methods have been applied to manufacture the porous structure, it was unable to visualize the pores and their interconnections within the ceramic and had objective measurement of the calcium phosphate ceramics. With the advance of biomedical imaging through micro-computed tomography (microCT), the study attempted to quantify the pore structure of different calcium phosphate ceramics. Three kinds of bioceramic blocks, namely BSC, ChronOS, and THA, were synthesized by three methods and tested in the study. Six blocks of each bioceramic were evaluated by conventional water immersion method and microCT. The pore size and connectivity of the pores were evaluated with standardized protocols. The three-dimensional analysis of the pores and their distribution by microCT was presented. The ChronOS had more functional pores (200-400μm in diameter) than the BSC and THA did (p<0.05). Providing objective information on the functional pores, the microCT evaluation serves as a good standard for specification of the bioceramic-related implants.

APA, Harvard, Vancouver, ISO, and other styles

18

Chung, Ren Jei, M. F. Hsieh, K. C. Huang, Fong In Chou, and L. H. Perng. "Preparation of Porous HA/Beta-TCP Biphasic Bioceramic Using a Molten Salt Process." Key Engineering Materials 309-311 (May 2006): 1075–78. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.1075.

Full text

Abstract:

Bioceramics based on calcium phosphate is convinced to be well biocompatible after abundant researches. In this study, a biphasic bioceramic block (10 mm by 5 mm) (BBB) composed of hydroxyapatite and beta-tricalcium phosphate (40/60 in wt%) was prepared using a molten salt approach. At 800oC, the molten sodium chloride well helped the sintering of the precursor powders. A second calcination at 1000oC was then used to evaporate the salt so that a pure biphasic bioceramic block was obtained. This approach can provide porous BBB with 60% porosity, and powder x-ray diffraction patterns ensured the phasic compositions. However, the electrom probe microanalysis showed that around 2 at% of sodium was retained in the BBB. Scanning electron microscope revealed well-dispersed connective micro-pores of 3 micron and random macro-pores of >100 micron in the BBB. Because the salt was evaporated during the preparation of the BBB, the spatial voids were created, and, as a result. The compressive strength of the BBB can only reach a value of 3 MPa. Subcutaneous implantation of the BBB in mice showed that both acute and chronic imflammation were mild. In summary, the molten salt approach is feasible to fabricate biphasic calcium phosphate ceramics having controlled porosity.

APA, Harvard, Vancouver, ISO, and other styles

19

Ozyegin, L. S., Felix Sima, Carmen Ristoscu, Ismail Akin Kiyici, Ion N. Mihailescu, Onur Meydanoglu, Simeon Agathopoulos, and F. N. Oktar. "Sea Snail: An Alternative Source for Nano-Bioceramic Production." Key Engineering Materials 493-494 (October 2011): 781–86. http://dx.doi.org/10.4028/www.scientific.net/kem.493-494.781.

Full text

Abstract:

The production of nano-calcium phosphate, such as HA (hydroxyapatite), materials from synthetic chemicals could sometimes lead to a costly and tedious work. Sea creatures could be an alternative way to produce very fine and even nano-structured calcium phosphate materials. Nacres vastly consist of rich calcium carbonate and/or aragonite mater. With simple conversion methods, like hotplate stirring, various bioceramic structures could be produced suitable for thin film coatings with various methods, like pulsed laser deposition (MAPLE). This study is part of a bigger project which eventually and ultimately aims to produce nano-phases of calcium phosphate biocompatible bioceramics, which can be used for biomedical coatings. In this particular study, we focus at transforming chemically, using hotplate stirring method, local sea snail shells rapana thomasiana. Cleaned sea snail samples were provided from local markets in Istanbul. The shells were smashed down, ball-milled and the powder was sieved (<100 µm powder particles). Differential thermal analysis (DTA/TG) was employed to evaluate the exact CaCO3 content of the shells. According to these results, the required volume of H3PO4 was added in order to set the molar ratio of Ca/P (during hotplate stirring) either 10/6 or 3/2 (these ratios correspond to HA and TCP, respectively). SEM and X-ray diffraction analyses were conducted. The SEM observations showed brick-like particles were formed with sizes <5 µm. From the X-ray diffraction analysis, predominantly monetite, which can be considered as a precursor of HA and TCP, was detected. The results of this study showed that to produce HA and other bioceramic phases, hot-plate stirring method is a reliable, fast, rapid and economic method when compared to other tedious HA production methods. Moreover, sea snail shells are very good candidate materials to produce fine powders with hotplate stirring method for various tissue engineering applications.

APA, Harvard, Vancouver, ISO, and other styles

20

Mehdikhani, Behzad, and Gholam Hossein Borhani. "Densification and Mechanical Behavior of β-Tricalcium Phosphate Bioceramics." International Letters of Chemistry, Physics and Astronomy 36 (July 2014): 37–49. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.36.37.

Full text

Abstract:

Nano-size β-tricalcium phosphate powders with average grain size of 80 nm were prepared by the wet chemical precipitation method with calcium nitrate and di-ammonium hydrogen phosphate as calcium and phosphorus precursors, respectively. The precipitation process employed was also found to be suitable for the production of sub-micrometre β-TCP powder in situ. The sinterability of the nano-size powders, and the microstructure, mechanical strength of the prepared β-TCP bioceramics were investigated. Bioceramic sample characterization was achieved by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), and density measurements. Powders compacted and sintered at 800, 900, 1000 and 1100 °C showed an increase in relative density from 70 % to 93 %. The results revealed that the maximum hardness of 240 H was obtained for β-TCP sintered at 1100 °C.

APA, Harvard, Vancouver, ISO, and other styles

21

Mehdikhani, Behzad, and Gholam Hossein Borhani. "Densification and Mechanical Behavior of β-Tricalcium Phosphate Bioceramics." International Letters of Chemistry, Physics and Astronomy 36 (July 15, 2014): 37–49. http://dx.doi.org/10.56431/p-e9cl64.

Full text

Abstract:

Nano-size β-tricalcium phosphate powders with average grain size of 80 nm were prepared by the wet chemical precipitation method with calcium nitrate and di-ammonium hydrogen phosphate as calcium and phosphorus precursors, respectively. The precipitation process employed was also found to be suitable for the production of sub-micrometre β-TCP powder in situ. The sinterability of the nano-size powders, and the microstructure, mechanical strength of the prepared β-TCP bioceramics were investigated. Bioceramic sample characterization was achieved by powder X-ray diffraction (XRD), scanning electron microscopy (SEM), fourier transform infrared spectroscopy (FTIR), and density measurements. Powders compacted and sintered at 800, 900, 1000 and 1100 °C showed an increase in relative density from 70 % to 93 %. The results revealed that the maximum hardness of 240 H was obtained for β-TCP sintered at 1100 °C.

APA, Harvard, Vancouver, ISO, and other styles

22

Yang, W. Z., D. L. Zhou, G. F. Yin, and G. D. Li. "Surface modification of biphasic calcium phosphate bioceramic powders." Applied Surface Science 255, no. 2 (November 2008): 477–79. http://dx.doi.org/10.1016/j.apsusc.2008.06.182.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

Zhao, Rui, Siyu Chen, Bo Yuan, Xuening Chen, Xi Yang, Yueming Song, Hai Tang, Xiao Yang, Xiangdong Zhu, and Xingdong Zhang. "Healing of osteoporotic bone defects by micro-/nano-structured calcium phosphate bioceramics." Nanoscale 11, no. 6 (2019): 2721–32. http://dx.doi.org/10.1039/c8nr09417a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Zamparini, Fausto, Carlo Prati, Paola Taddei, Andrea Spinelli, Michele Di Foggia, and Maria Giovanna Gandolfi. "Chemical-Physical Properties and Bioactivity of New Premixed Calcium Silicate-Bioceramic Root Canal Sealers." International Journal of Molecular Sciences 23, no. 22 (November 11, 2022): 13914. http://dx.doi.org/10.3390/ijms232213914.

Full text

Abstract:

The aim of the study was to analyze the chemical–physical properties and bioactivity (apatite-forming ability) of three recently introduced premixed bioceramic root canal sealers containing varied amounts of different calcium silicates (CaSi): a dicalcium and tricalcium silicate (1–10% and 20–30%)-containing sealer with zirconium dioxide and tricalcium aluminate (CERASEAL); a tricalcium silicate (5–15%)-containing sealer with zirconium dioxide, dimethyl sulfoxide and lithium carbonate (AH PLUS BIOCERAMIC) and a dicalcium and tricalcium silicate (10% and 25%)-containing sealer with calcium aluminate, tricalcium aluminate and tantalite (NEOSEALER FLO). An epoxy resin-based sealer (AH PLUS) was used as control. The initial and final setting times, radiopacity, flowability, film thickness, open pore volume, water absorption, solubility, calcium release and alkalizing activity were tested. The nucleation of calcium phosphates and/or apatite after 28 days aging in Hanks balanced salt solution (HBSS) was evaluated by ESEM-EDX, vibrational IR and micro-Raman spectroscopy. The analyses showed for NeoSealer Flo and AH Plus the longest final setting times (1344 ± 60 and 1300 ± 60 min, respectively), while shorter times for AH Plus Bioceramic and Ceraseal (660 ± 60 and 720 ± 60 min, respectively). Radiopacity, flowability and film thickness complied with ISO 6876/12 for all tested materials. A significantly higher open pore volume was observed for NeoSealer Flo, AH Plus Bioceramic and Ceraseal when compared to AH Plus (p < 0.05), significantly higher values were observed for NeoSealer Flo and AH Plus Bioceramic (p < 0.05). Ceraseal and AH Plus revealed the lowest solubility. All CaSi-containing sealers released calcium and alkalized the soaking water. After 28 days immersion in HBSS, ESEM-EDX analyses revealed the formation of a mineral layer that covered the surface of all bioceramic sealers, with a lower detection of radiopacifiers (Zirconium for Ceraseal and AH Plus Bioceramic, Tantalum for NeoSealer Flo) and an increase in calcium, phosphorous and carbon. The calcium phosphate (CaP) layer was more evident on NeoSealer Flo and AH Plus Bioceramic. IR and micro-Raman revealed the formation of calcium carbonate on the surface of all set materials. A thin layer of a CaP phase was detected only on AH Plus Bioceramic and NeoSealer Flo. Ceraseal did not show CaP deposit despite its highest calcium release among all the tested CaSi-containing sealers. In conclusion, CaSi-containing sealers met the required chemical and physical standards and released biologically relevant ions. Slight/limited apatite nucleation was observed in relation to the high carbonation processes.

APA, Harvard, Vancouver, ISO, and other styles

25

Gintu, Agung Rimayanto, Elisabeth Betty Elok Kristiani, and Yohanes Martono. "Hydroxiapatite (HAp) Bioceramics Made from The Caletaiya presclupta Snail Shells from Poso Lake." JKPK (Jurnal Kimia dan Pendidikan Kimia) 5, no. 3 (December 31, 2020): 254. http://dx.doi.org/10.20961/jkpk.v5i3.45983.

Full text

Abstract:

Bioceramic Hydroxyapatite (HAp) was a derivated chemical synthetic compound from calcium phosphate commonly used to care for hard tissue damage. Bioceramic Hydroxyapatite can be synthesized from the compounds rich with calcium contains. This study treated the synthesis and physicochemical Characterization of the HAp made from Celetaiya persclupta snail shells obtained from Poso lake. From the characterization of the sample C. presclupta shells obtained the water contains 0.50±0.00%; ash contains 0.9913±0.0017g/g; potassium 0.0005±0.00007g/g; calcium 0.0391±0.0059g/g; phosphate 0.0221±0.0009g/g; phosphorus 0.0111±0.0005 and the ratio of Ca/P 1.7382±0.1994%. The synthesis of HAp by base precipitation method showed the yield of synthesis 85.2891±4.2496% with the level of material reduction during synthesis 18.0442±1.1684%. The result of characterization of the HAp showed that the potassium contains 0.0002±0.00003g/g; calcium 0.0121±0.0031g/g; phosphate 0.0167±0.0013g/g; phosphorus 0.0084±0.0007g/g; ratio of Ca/P 1.3724±0.2736%; porosity 9.9929±0.7626%; swelling ability 24.8416±1.4989%; and biodegradability 10.8958±1.1781%. The overall results concluded that the C. presclupta snail shells could become a source of Bioceramic Hydroxyapatite (HAp).

APA, Harvard, Vancouver, ISO, and other styles

26

Zaidi, Nur Zulaikha, Nur Raihan Ridzwan, Ahmed Hafedh Mohammed Mohammed, and Khairul Anuar Shariff. "Effect of Soaking Time on the Compositional and Morphological Changes of DCPD-Coated β-TCP Bioceramic." Key Engineering Materials 908 (January 28, 2022): 135–40. http://dx.doi.org/10.4028/p-i0p5c7.

Full text

Abstract:

The aim of this study is to investigate the effect of soaking time on the compositional and morphological changes of dicalcium phosphate dihydrate (DCPD)-coated β-tricalcium phosphate (β-TCP) bioceramic. In this study, an established method from our research group was used to prepare the β-TCP bioceramic pellets and expose them to acidic calcium phosphate solution for 2, 4, 6, and 8 hours to obtain DCPD coated layer on β-TCP pellets through dissolution-precipitation reaction. Characterization methods such as x-ray diffraction analysis (XRD) and scanning electron microscope (SEM) were carried out on the specimen. XRD and SEM analyses indicated that the peak intensity and density of DCPD crystal precipitated on the pellets were increased when increasing the soaking time. Therefore, it was confirmed that the DCPD coated layer formation on the β-TCP pellet surfaces depended on the exposure time to acidic calcium phosphate solution.

APA, Harvard, Vancouver, ISO, and other styles

27

Kel, D., Hasan Gökçe, D. Bilgiç, D. Ağaoğulları, I. Duman, M. L. Öveçoğlu, Eyup Sabri Kayali, Ismail Akin Kiyici, Simeon Agathopoulos, and F. N. Oktar. "Production of Natural Bioceramic from Land Snails." Key Engineering Materials 493-494 (October 2011): 287–92. http://dx.doi.org/10.4028/www.scientific.net/kem.493-494.287.

Full text

Abstract:

There are thousands of land snail species, ranging in size from 1 mm to the Giant African Snail growing up to a foot long. Two species, known as escargot, helix aspersa and helix pomatia, are commercially important. Helix pomatia is abundant in Turkey. Those snails are exported usually without shells. Shells are damped to trash sites or used as substitute food for animals. The shell is rich in calcium carbonate and some other minor minerals. Thus, snails’ shells can be used as a source for bioceramic production. So far, in the literature there are lot of papers about converting calcite and aragonite structures to hydroxyapatite (HA), like corals, sea shells, sea urchin and other sea creatures. However, there is very limited information about converting land snail shells to HA and other bioceramic phases. The aim of this work was to produce various phases of bioceramic materials from land snails’ shells which are left as a residue waste after their export procedures. Empty local land snails’ shells (helix pomatia) were collected in Istanbul. They were washed, dried, crushed and ball milled until a powder of 100 µm particles size was obtained. Raw powders were stirred at 80°C for 15 min on a hotplate. A second part of the raw powder was stirred with an ultrasonic stirrer at 80°C for 15 min in an ultrasonic equipment. Equivalent amount of H3PO4 was added drop by drop into the solution. The reaction lasted for 8h. Then, to evaporate the liquid part, the mixtures were put into an incubator at 100°C for 24 h and the resultant dried sediments were collected. The produced powders were analyzed with X-ray diffraction, IR and scanning electron microscope (SEM). The experimental results confirmed the formation of various Ca-phosphates, specifically monetite, fluorapatite and some other minor calcium phosphate phases. Bioceramic production from land snail is a reliable and economic way comparing to other tedious methods of producing synthetic HA and other various bioceramics phases.

APA, Harvard, Vancouver, ISO, and other styles

28

Oktar, Faik Nüzhet, Simeon Agathopoulos, Lutfiye Sevgi Ozyegin, I. G. Turner, O. Gunduz, N. Demirkol, S. Brück, et al. "Nano-Bioceramic Production via Mechano-Chemical Conversion (Ultrasonication)." Key Engineering Materials 529-530 (November 2012): 609–14. http://dx.doi.org/10.4028/www.scientific.net/kem.529-530.609.

Full text

Abstract:

The production of nano-calcium phosphate powders, such as HA (hydroxyapatite), from synthetic chemicals can be expensive and time consuming. The skeleton or shells of sea creatures (e.g. sea urchins, shells, corals) could be an alternative source of materials to produce very fine and even nano-structured calcium phosphate biomaterial powders. Ηydrothermal conversion under very high pressures or methods such as hot-plating (chemical) or ultrasonication (mechano-chemical), have been proposed to transform naturally derived CaCO3, e.g. aragonite, into apatite based materials. The aim of the present work was to prepare inexpensive nano-sized HA and TCP bioceramics powders from a local sea snail shells as a possible raw material for HA/TCP bioceramics. Empty shells of a local sea snail (Nassarius hinia reticulatus) from Marmara Sea, Turkey were collected from a beach near Istanbul. The collected shells were ground to a particle size <75µm. Thermal analyses (DTA/TGA) were performed to determine the exact CaCO3content and thermal behavior. The raw powder was suspended in an aqueous media which was placed in an ultrasonic bath. The temperature was set at 80°C for 15min. Then, an equivalent (to CaO content) amount of H3PO4was added drop by drop very gently into the solution. The reaction continued for 8h, following which the liquid component was evaporated off in an incubator at 100°C for 24h. The dried sediment was collected and heat treated at two different temperatures, 400 and 800°C. The morphology of the powders produced was examined using SEM. The crystalline phases were indentified using X-ray analysis. X-ray diffractograms indicated the presence of two calcium phosphate phases, namely HA and whitlockite. SEM observations showed that the powder produced comprised nano-sized particles. FTIR results also indicated the presence of HA and whitlockite structures. The experimental results suggest thatNassariushinia reticulatusshells could be an alternative source for the production of various mono or biphasic calcium phosphates. In this study, local sea snail shells were successfully converted to HA and whitlockite with a simple mechano-chemical (ultrasonic) conversion method without the use of complex hydrothermal methods.

APA, Harvard, Vancouver, ISO, and other styles

29

Baroth, Serge, Xavier Bourges, Eric Goyenvalle, Eric Aguado, and Guy Daculsi. "Injectable biphasic calcium phosphate bioceramic: The HYDROS® concept." Bio-Medical Materials and Engineering 19, no. 1 (2009): 71–76. http://dx.doi.org/10.3233/bme-2009-0565.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Daculsi, G., Thomas Miramond, Pascal Borget, and Serge Baroth. "Smart Calcium Phosphate Bioceramic Scaffold for Bone Tissue Engineering." Key Engineering Materials 529-530 (November 2012): 19–23. http://dx.doi.org/10.4028/www.scientific.net/kem.529-530.19.

Full text

Abstract:

The development of CaP ceramics involved a better control of the process of resorption and bone substitution. Micro Macroporous Biphasic CaP, (MBCP+) is a concept based on an optimum balance of the more stable phase of HA and more soluble TCP. The material is soluble and gradually dissolves in the body, seeding new bone formation as it releases Ca and P ions into the biological medium. The MBCP+ is selected for tissue engineering in a large European research program on osteoinduction and mesenchymal stem cell technology (REBORNE 7thEU frame work program, Regenerative Bone defects using New biomedical Engineering approaches,www.reborne.org). We have optimized the matrices in terms of their physical, chemical, and crystal properties, to improve cell colonization and to increase kinetic bone ingrowth. The fast cell colonization and resorption of the material are associated to the interconnected macropores structure which enhances the resorption bone substitution process. The micropore content involves biological fluid diffusion and suitable adsorption surfaces for circulating growth factors. The bioceramics developed for this project was fully characterized using X-Ray diffraction, FTIR, X-rays micro tomography, Hg porosimetry, BET specific surface area, compressive mechanical test, and SEM. Preclinical tests on the optimized scaffold were realized in critical size defects in several sites of implantation and animals (rats, rabbits, goats, dogs).The smart scaffold has a total porosity of 73%, constituted of macropores (>100µm), mesopores of 10 to 100µm and high micropores (<10µm) content of more or less 40%. The crystal size is <0.5 to 1 µm and the specific surface area was around 6m2/g. Thein vivoexperiment indicated higher colonization by osteogenic cells demonstrating suitable matrices for tissue engineering. The HA/TCP ratio of 20/80 was also more efficient for combination with total bone marrow or stem cell cultivation and expansion before to be implanted.

APA, Harvard, Vancouver, ISO, and other styles

31

Tas, A. Cueneyt. "ChemInform Abstract: Combustion Synthesis of Calcium Phosphate Bioceramic Powders." ChemInform 32, no. 9 (February 27, 2001): no. http://dx.doi.org/10.1002/chin.200109243.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Sadiq, Taoheed Olohunde, Izman Sudin, Jamaliah Idris, and Nor Akmal Fadil. "Synthesis Techniques of Bioceramic Hydroxyapatite for Biomedical Applications." Journal of Biomimetics, Biomaterials and Biomedical Engineering 59 (February 14, 2023): 59–80. http://dx.doi.org/10.4028/p-yqw75e.

Full text

Abstract:

The need to develop surviving implants and bone substitutes with good biocompatibility, mechanical strength and bioactivity, without causing toxicity, immune rejection and cancer had attracted the attention of many researchers over the years. Hydroxyapatite (HA) is one of the excellent calcium phosphates and major mineral component of vertebrate bone and teeth, which considerably enhances the biocompatibility, mechanical strength and bioactivity of artificial biomaterials in the body system. In addition, it creates porous and rough coated surface that aids the cell attachment, proliferation and the growth of tissue on the bone implants. Due to its high demand in biomedical applications, scientists had developed several, simple and efficient techniques to produce HA. This review outlines several techniques of manufacturing HA and summarizes the merits and demerits of each technique. Keywords: Biomaterials, calcium phosphate, hydroxyapatite, preparation techniques and bone

APA, Harvard, Vancouver, ISO, and other styles

33

Furko, Monika, Katalin Balázsi, and Csaba Balázsi. "Calcium Phosphate Loaded Biopolymer Composites—A Comprehensive Review on the Most Recent Progress and Promising Trends." Coatings 13, no. 2 (February 5, 2023): 360. http://dx.doi.org/10.3390/coatings13020360.

Full text

Abstract:

Biocompatible ceramics are extremely important in bioengineering, and very useful in many biomedical or orthopedic applications because of their positive interactions with human tissues. There have been enormous efforts to develop bioceramic particles that cost-effectively meet high standards of quality. Among the numerous bioceramics, calcium phosphates are the most suitable since the main inorganic compound in human bones is hydroxyapatite, a specific phase of the calcium phosphates (CaPs). The CaPs can be applied as bone substitutes, types of cement, drug carriers, implants, or coatings. In addition, bioresorbable bioceramics have great potential in tissue engineering in their use as a scaffold that can advance the healing process of bones during the normal tissue repair process. On the other hand, the main disadvantages of bioceramics are their brittleness and poor mechanical properties. The newest advancement in CaPs doping with active biomolecules such as Mg, Zn, Sr, and others. Another set of similarly important materials in bioengineering are biopolymers. These include natural polymers such as collagen, cellulose acetate, gelatin, chitosan, and synthetic polymers, for example, polyvinyl pyrrolidone (PVP), polyvinyl alcohol (PVA), and polycaprolactone (PCL). Various types of polymer have unique properties that make them useful in different fields. The combination of CaP particles with different biopolymers gives rise to new opportunities for application, since their properties can be changed and adjusted to the given requirements. This review offers an insight into the most up-to-date advancements in the preparation and evaluation of different calcium phosphate–biopolymer composites, highlighting their application possibilities, which largely depend on the chemical and physical characteristics of CaPs and the applied polymer materials. Overall, these composites can be considered advanced materials in many important biomedical fields, with potential to improve the quality of healthcare and to assist in providing better outcomes as scaffolds in bone healing or in the integration of implants in orthopedic surgeries.

APA, Harvard, Vancouver, ISO, and other styles

34

Wang, Ying Chun, Yu Yong Yang, and Mei Chun Wang. "Bioceramic Composite Coatings Fabricated by Nd-YAG Laser Cladding Process on Ti6Al4V Substrate." Applied Mechanics and Materials 198-199 (September 2012): 68–71. http://dx.doi.org/10.4028/www.scientific.net/amm.198-199.68.

Full text

Abstract:

Laser cladding technology was adopted to fabricate hydroxyapatite(HAP) and calcium phosphate compound coating according to the feature that a metallurgical bonding can be formed by laser cladding process. Compared with CO2laser, Nd-YAG laser has different wavelength(the former is 1.06μm and the latter is 10.06μm). Metal and ceramic material has quite different absorbance ability towards them and thus they can generate different laser cladding products by these two laser surface processings with different wavelength. This paper presents a new process and mechanism analysis to obtain bioceramic composite coating on Ti6Al4V substrate by Nd-YAG laser cladding. A bioceramic composite coating including HAP，Ca2P2O7，Ca3(PO4)2and calcium titanates and was successfully obtained by Nd-YAG laser cladding with pre-depositing mixed powders of CaHPO4•2H2O and CaCO3directly on Ti6Al4V substrate. Nd-YAG laser transmits mixed powders of CaHPO4•2H2O and CaCO3and the laser power is absorbed by Ti6Al4V substrate to produce a thin layer of molten region. There are mainly two kinds of chemical reaction systems in the coating during laser cladding processing. When CaHPO4•2H2O and CaCO3react together, they make calcium phosphate bioceramic products; The microstructure of the bioceramic composite coating is even and minute because of the rapid solidification in laser processing. A chemical metallergical bonding is formed between the boceramic composite coating and Ti6Al4V substrate. It can also be expected that Nd-YAG laser cladding technology can be used as a further modification procedure to enhance HAp/metal interface property.

APA, Harvard, Vancouver, ISO, and other styles

35

Trujillo-Hernández, Margarita, Rebeca E. Flores-Ventura, Angélica Suárez-Porras MSc, Leandro García-González PhD, Julián Hernández-Torres PhD, Luis Zamora-Peredo PhD, and José Luis Suárez-Franco DDS, MSc, PhD. "Comparative Study of the Bioactivity of Two Bioceramic Materials." Odovtos - International Journal of Dental Sciences 21, no. 2 (August 31, 2018): 73–81. http://dx.doi.org/10.15517/ijds.v21i2.37061.

Full text

Abstract:

Calcium silicate-based materials have been shown to be bioactive due to their ability to produce biologically compatible carbonated apatite. The objective of this study was to analyze the bioactivity of Biodentine ™ and MTA Repair HP® in contact with human dentine discs, which were sealed and divided randomly to form four groups: group 1 Biodentine™, group 2 MTA Repair HP®, positive control group MTA Angelus® and negative control group IRM®, which were incubated in PBS solution for 10 days, for a subsequent analysis by means of MEB-EDS and Raman spectroscopy. The three calcium-based materials analyzed in this study proved to be bioactive because upon contact with a phosphate-based solution they were triggered at the onset of amorphous calcium phosphate, as the precursor during the formation of carbonated apatite.

APA, Harvard, Vancouver, ISO, and other styles

36

Jian-Min, Zhang, Lin Chang-Jian, Feng Zu-De, and Tian Zhao-Wu. "Electrodeposition Technique for Calcium Phosphate Bioceramic Coatings on Ti6Al4V Substrate." Acta Physico-Chimica Sinica 14, no. 08 (1998): 698–703. http://dx.doi.org/10.3866/pku.whxb19980806.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Manjubala, I., and T. P. Sastry. "Structural and Morphological Analysis of Functionally Graded Calcium Phosphate Bioceramic." Key Engineering Materials 218-220 (November 2001): 89–92. http://dx.doi.org/10.4028/www.scientific.net/kem.218-220.89.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Zhu, Yizhi, Qibin Liu, Peng Xu, Long Li, Haibing Jiang, and Yang Bai. "Bioactivity of calcium phosphate bioceramic coating fabricated by laser cladding." Laser Physics Letters 13, no. 5 (March 21, 2016): 055601. http://dx.doi.org/10.1088/1612-2011/13/5/055601.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Ghosh, Rupita, and Ritwik Sarkar. "Comparative Analysis of Novel Calcium Phosphate Based Machinable Bioceramic Composites." Transactions of the Indian Ceramic Society 79, no. 3 (July 2, 2020): 131–38. http://dx.doi.org/10.1080/0371750x.2020.1773931.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Rafeek, A. D., G. Choi, and L. A. Evans. "Morphological, spectroscopic and crystallographic studies of calcium phosphate bioceramic powders." Journal of the Australian Ceramic Society 54, no. 1 (September 22, 2017): 161–68. http://dx.doi.org/10.1007/s41779-017-0137-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Mehrban, Nazia, James Bowen, Elke Vorndran, Uwe Gbureck, and Liam M. Grover. "Structural changes to resorbable calcium phosphate bioceramic aged in vitro." Colloids and Surfaces B: Biointerfaces 111 (November 2013): 469–78. http://dx.doi.org/10.1016/j.colsurfb.2013.06.020.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Hsu, Y. H., I. G. Turner, and A. W. Miles. "Fabrication and mechanical testing of porous calcium phosphate bioceramic granules." Journal of Materials Science: Materials in Medicine 18, no. 10 (June 7, 2007): 1931–37. http://dx.doi.org/10.1007/s10856-007-3128-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Yang, Sen, and Hau Chung Man. "Enhancing the Bonding Strength of Plasma-Sprayed HA Coating on Pure Ti." Materials Science Forum 561-565 (October 2007): 1553–56. http://dx.doi.org/10.4028/www.scientific.net/msf.561-565.1553.

Full text

Abstract:

A layer of bioceramic HA was coated on laser gas nitrided and grit-blasted pure Ti substrates using plasma-spraying technique, respectively. X-ray diffraction analysis showed that the microstructures of the coating were mainly composed of HA, amorphous calcium phosphate and some minute phases of tricalcium phosphate, tetracalcium phosphate and calcium oxide. The experimental results showed that the 3-D TiN dendritic scaffold structure produced on the surface of pure Ti using laser gas nitriding technique in advance could anchor the HA coating and improved the interfacial adherence significantly as compared with those on the grit blasted surfaces.

APA, Harvard, Vancouver, ISO, and other styles

44

Petronis, Sandris, Janis Locs, Vita Zalite, Mara Pilmane, Andrejs Skagers, Ilze Salma, and Girts Salms. "Impact of Biphasic Calcium Phosphate Bioceramics on Osteoporotic Hip Bone Mineralization In Vivo Six Months after Implantation." Key Engineering Materials 721 (December 2016): 229–33. http://dx.doi.org/10.4028/www.scientific.net/kem.721.229.

Full text

Abstract:

Calcium bone substitutes are successfully used for local recovery of osteoporotic bone and filling of bone defects. Previous studies revieled that biphasic calcium phosphate (BCP) show better bioactivity in compare to pure β-tricalcium phosphate or hydroxyapatite. Also increased porosity of material promotes better bone tissue response. Aim of this experiment was to evaluate immunohistologically response of osteoporotic bone of experimental animal to implantation of granules with hydroxyapatite/β-tricalcium phosphate (HAp/β-TCP) ratio of 90/10. Calcium phosphate (CaP) was synthesized by aqueous precipitation technique from calcium hydroxide and phosphoric acid. Bioceramic granules in size range from 1.0 to 1.4 mm were prepared with nanopore sizes around 200 nm. We used nine female rabbits with induced osteoporosis in this experiment. Six animals in study group underwent implantation of BCP in hip bone defect and three animals in control group left without BCP implantation. After 6 months animals were euthanized, bone samples collected and proceeded for detection of bone activity and repair markers: osteocalcin (OC), osteopontin (OP) and osteoprotegerin (OPG). Controls showed the presence of experimental bone osteoporosis. In experimental group bone showed partially resorbed bioceramic granules and in some samples new bone formation near the granuli was observed. Increase of OC and OPG up to twice as to compare to control group were detected as well. Implantation of BCP granules in osteoporotic rabbit bone increases expression of OC and OPG indicating the activation of osteoblastogenesis and bone mineralization in vivo.

APA, Harvard, Vancouver, ISO, and other styles

45

Olivier, Florian, Q. Picard, S. Delpeux, F. Fayon, J. Chancolon, F. Warmont, N. Rochet, and S. Bonnamy. "Synthesis and Characterization of Biomimetic Strontium Substituted Carbonated Calcium-Deficient Hydroxyapatite Deposited on Carbon Fiber Cloths." Key Engineering Materials 758 (November 2017): 199–203. http://dx.doi.org/10.4028/www.scientific.net/kem.758.199.

Full text

Abstract:

Calcium phosphate (CaP) ceramics, e.g. hydroxyapatite Ca10(PO4)6(OH)2 (HAP) and tricalcium phosphate Ca3(PO4)2 (TCP), are widely employed in the field of bone tissue engineering due to their controlled biodegradability and excellent biocompatibility. In the present study, the chemical composition, microtexture and structure of CaP deposits on carbon fiber cloths (CFC) are investigated. Coatings of CaP or strontium-substituted calcium phosphate (Sr-CaP) on CFC are obtained by sono-electrodeposition process using cathodic polarization. At constant potential, the deposits consist in a biomimetic carbonated calcium-deficient hydroxyapatite (CaD-HAP), having a plate-like morphology with the possibility to control the Sr2+ incorporation. In orthopaedic field, CaP or Sr-CaP coated carbon fiber cloths offer new promising bioceramic materials for bone repair and regeneration.

APA, Harvard, Vancouver, ISO, and other styles

46

Sridhar, T. M., R. Praveen, S. Shanmugaraj, S. K. Srinivas, and D. Das. "Crystallographic Changes of Bioceramic Composition of Cadever Bone on Heat Treatments." Key Engineering Materials 361-363 (November 2007): 219–22. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.219.

Full text

Abstract:

Bone is a complicated heterogeneous, viscoelastic, anisotropic material. Its properties depend on the nature of mechanical forces in addition to the location as well as the age, sex and race of the subject. Human humerus bones retrieved from cadavers were selected and separated in to cortical and cancellous parts. They were heat treated at different temperatures 400°C, 600°C and 800°C respectively to study the crystalline nature and composition of cortical and cancellous region of the humerus bone separately. Hydroxyapatite (HAP) was present as the major phase in the bone powders at 600 and 800°C with well resolved peaks along with other mineral phases of calcium phosphate. No amorphous phases were present indicating that the crystal structure of calcium phosphate compounds is present in crystalline form. FTIR studies further confirm the presence of phosphate vibrational modes of the entire bone mineral along with the presence of carbonates and hydroxyl groups.

APA, Harvard, Vancouver, ISO, and other styles

47

Ektessabi, A. M., and M. Hamdi. "Characterization of calcium phosphate bioceramic films using ion beam analysis techniques." Surface and Coatings Technology 153, no. 1 (April 2002): 10–15. http://dx.doi.org/10.1016/s0257-8972(01)01519-5.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Wang, Diangang, Chuanzhong Chen, Jie Ma, and Tingquan Lei. "Microstructure of yttric calcium phosphate bioceramic coatings synthesized by laser cladding." Applied Surface Science 253, no. 8 (February 2007): 4016–20. http://dx.doi.org/10.1016/j.apsusc.2006.08.036.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

El-Ghannam, Ahmed. "Bioceramic Drug Delivery System for Cancer Treatment and Regenerative Medicine." Key Engineering Materials 696 (May 2016): 245–49. http://dx.doi.org/10.4028/www.scientific.net/kem.696.245.

Full text

Abstract:

Silica-calcium-phosphate composite (SCPC) is a drug delivery platform that has successfully demonstrated the ability to bind and release several therapeutics including antibiotics, peptides, anticancer drugs, and growth factors. It has successfully demonstrated a unique capacity for bone regeneration. The present studies address the effect of the phosphate and silicate functional groups on drug binding and controlled release kinetics of Cisplatin (Cis). Moreover, the roles of ceramic composition and resorbability on rhBMP2 release kinetics and bone regeneration in a critical size calvarial defect in rabbit is presented.

APA, Harvard, Vancouver, ISO, and other styles

50

Wang, Ying Chun, Yan Min Li, Zhen Min Xu, Qi Lin Deng, Jian Guo Li, and Yao He Zhou. "Microstructure and Bonding Feature of the Bioceramic Composite Coating Obtained by Nd: YAG Laser Cladding." Key Engineering Materials 361-363 (November 2007): 697–700. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.697.

Full text

Abstract:

Undesirable phase and microstructure formation, and poor HAP/metal bonding strength restrict the fabrication technique to obtain HAP and other calcium phosphate ceramic coatings. In this paper a bioceramic composite coating, which includes HAP andβ-Ca2P2O7, was obtained by laser cladding with pre-depositing mixed powders of CaHPO4·2H2O and CaCO3 directly on the 316L stainless steel metal substrate. The phases, microstructure and bonding feature of the bioceramic composite coating are characterized by X-ray diffraction(XRD), scanning electron microscopy-energy dispersive spectroscopy(SEM-EDS). The microstructure of the coating consists of minute granular HAP that is distributed among the overlapped club-shapedβ-Ca2P2O7. Uniform presences of Ca, P and O in bioceramic composite coating supplie necessary elements for the synthesis of HAP andβ-Ca2P2O7. Diffusions inwards of P and O into alloying layer help form the chemical metallurgical bonding and composition gradient distributions are present. a chemical metallurgical bonding was formed between the bioceramic composite coating and metal substrate.

APA, Harvard, Vancouver, ISO, and other styles

Journal articles on the topic 'Calcium phosphate bioceramic'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles