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Journal articles on the topic 'CAE'

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Author: Grafiati

Published: 4 June 2021

Last updated: 11 March 2023

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1

Luo, Yu, Jiani Tang, Xu Liu, Jianping Qiu, Zi Ye, Yan Lai, Yian Yao, Jimin Li, Xiaodong Wang, and Xuebo Liu. "Coronary Artery Aneurysm Differs From Coronary Artery Ectasia: Angiographic Characteristics and Cardiovascular Risk Factor Analysis in Patients Referred for Coronary Angiography." Angiology 68, no. 9 (August 27, 2016): 823–30. http://dx.doi.org/10.1177/0003319716665690.

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The differences in angiographic characteristics and cardiovascular (CV) risk factors between coronary artery aneurysm (CAA) and coronary artery ectasia (CAE) have not been compared systematically. Of 10 876 patients undergoing coronary angiography, patients with CAA (n = 85) and CAE (n = 51) were screened. The prevalence of CAA was greater than that of CAE ( P < .05). The right coronary artery was the most involved (70.6%) in CAE compared with left circumflex (52.9%) and left anterior descending (41.2%). Coronary artery aneurysm coexisted with coronary artery disease (CAD) more frequently than CAE ( P = .002), and the modified Gensini score of CAA was also higher than that of CAE ( P < .001). The average maximum diameter was smaller, and corrected Thrombolysis in Myocardial Infarction (TIMI) frame count was lower in CAA than CAE in all 3 coronary arteries ( P < .001). Multivariate analysis showed that hyperlipidemia ( P = .02), smoking ( P = .04), and family history of CAD ( P = .02) were the independent variables most strongly associated with CAA, but not CAE. This study suggests that there are significant differences in coronary angiographic characteristics and CV risk factors between CAA and CAE.

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2

Babu, Numbury Surendra, and Didugu Jayaprakash. "Computational Study of the Stability of Tautomers and equilibrium constants of Cyanuric acid (CA) in Different solvents." JOURNAL OF ADVANCES IN CHEMISTRY 11, no. 2 (January 22, 2015): 3485–97. http://dx.doi.org/10.24297/jac.v11i2.6691.

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In the present investigation, the tautomeric and equilibrium of Cyanuric acid has been studied using Hartifock (HF) method in the gas phase and different solvents using the PCM model. The relative energies of these tautomers have been calculated at the HF level of theory using 6-311++ G (d,p) basis set. Energetics and relative stabilities of the tautomers were compared and analyzed in both the gaseous and different solvents. The results indicate that the keto tautomer (CA1) is the most stable form in the gas phase and other solvents. The order of stability of isomers was found to be CA1 > CA3> CA11> CA2> CA6> CA10> CA7> CA4> CA5> CA9>CA8. Having the largest dipole moment the CA8 tautomer is expected to have the strongest interaction with polar solvents. The HF method calculated tautomeric equilibrium constants with respect to the most stable tautomer CA1 of Cyanuric acid both in the gas and in different solvents. The of the equilibrium constants calculated starting from the general outline of interconversion.

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3

KASE, Kiwamu. "An Introduction of Outline of CAD/CAE/CAM/CAT (1)." Journal of the Japan Society for Precision Engineering 79, no. 2 (2013): 144–47. http://dx.doi.org/10.2493/jjspe.79.144.

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4

KASE, Kiwamu. "An Introduction of Outline of CAD/CAE/CAM/CAT (2)." Journal of the Japan Society for Precision Engineering 79, no. 3 (2013): 223–26. http://dx.doi.org/10.2493/jjspe.79.223.

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5

KASE, Kiwamu. "An Introduction of Outline of CAD/CAE/CAM/CAT (3)." Journal of the Japan Society for Precision Engineering 79, no. 4 (2013): 309–13. http://dx.doi.org/10.2493/jjspe.79.309.

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6

Thilmany, Jean. "CAD meets CAE." Mechanical Engineering 121, no. 10 (October 1, 1999): 66–69. http://dx.doi.org/10.1115/1.1999-oct-4.

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This article focuses on engineering developments to integrate computer-aided engineering (CAE) and computer-aided design (CAD) capabilities in a software. CAD/CAE software suites are making their way to the forefront of current design practices, because they contain capabilities that allow designers to build an initial prototype that has already been analyzed by the CAE system for design flaws. Engineers at Cannondale have used an integrated CAD/CAE package to cut one year from the design time of their full-suspension Raven frame, which is both lightweight and stiff and has a suspension fork and a rear swing arm. The CAD software is used to design the bicycle frame while the CAE software immediately analyzes design flaws, which are then corrected, eliminating the need for continual prototyping. Companies are finding that the easy-to-learn nature of these CAD/CAE programs allows them to put analysis capability in the hands of design engineers for the first time.

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7

Yildirim, Nesligul, Ishak Ozel Tekin, Mehmet Arasli, and Mustafa Aydin. "Further Increase in the Expression of Activation Markers on Monocyte-Derived Dendritic Cells in Coronary Artery Disease Patients with Ectasia Compared to Patients with Coronary Artery Disease Alone." Mediators of Inflammation 2010 (2010): 1–6. http://dx.doi.org/10.1155/2010/748919.

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Background. Coronary artery ectasia (CAE) is defined as localized or diffuse dilation of the coronary arteries. There are scarce data about the role of dendritic cells in CAE development. In this study we investigated the activation markers on the surface of monocyte-derived dendritic cells (mDCs) in coronary artery disease (CAD) patients with or without CAE.Method. The study consisted of 6 patients who had obstructive CAD with CAE, 6 CAD patients without CAE and 6 subjects with angiographically normal coronary arteries. mDCs were cultivated from peripheral blood monocytes. Surface activation markers were detected by flow cytometry.Results. CAD patients with CAE were detected to have significantly higher mean fluorescence intensities of CD11b, CD11c, CD54 , CD83, CD86 and MHC Class II molecules on mDCs in comparison to CAD patients without CAE and normal controls ( for all). A significant positive correlation was found between the number of vessels with CAE and the levels of CD11c, CD86, and MHC Class II molecules.Conclusion. mDCs display an increased cell surface concentration of activation molecules in CAD patients with CAE compared to patients with CAD alone. DC activation may play an important role for CAE development in patients with CAD.

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8

Tony, Hasahya, Kai Meng, Bangwei Wu, and Qiutang Zeng. "Among Ectasia Patients with Coexisting Coronary Artery Disease, TIMI Frame Count Correlates with Ectasia Size and Markis Type IV Is the Commonest." Cardiology Research and Practice 2015 (2015): 1–5. http://dx.doi.org/10.1155/2015/282170.

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Background. Coronary artery ectasia (CAE) occurs in 0.3 to 5.3% of patients undergoing coronary angiography. TIMI frame count (TFC) is an index of coronary flow that correlates with flow velocity. In ectasia patients, there is delayed coronary flow with increased TFC.Methods.We evaluated angiograms of 789 patients for presence of CAE, coronary artery disease (CAD), and Markis type of CAE. We measured ectasia size and length and their correlation with TFC in ectatic right coronary arteries (RCA) of patients with CAE and CAD.Results.30 patients had CAE (3.8%). Of these 16.7% had isolated CAE, while 83.87% had CAE and CAD. Among CAE and CAD patients, the RCA was most involved (70.4%), and Markis type IV CAE was the commonest (64%). In isolated CAE, the RCA, LAD, and LCx were equally involved (33.3%). Patients with CAE and CAD had significantly higher TFC compared to controls,P=0.035. There was a positive correlation of moderate strength, between ectasia size and TFC,r(17) = 0.598,P=0.007. Ectasia length was not significantly correlated with TFC, rho (17) = 0.334,P=0.163.Conclusion.Among patients undergoing angiography, CAE has a prevalence of 3.8% and Markis type IV is the commonest. Larger ectasias are associated with slower coronary flow.

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9

Lu, Ya Ping, Lie Qin Wu, and Meng Chen. "Research and Exploit on the Integrated System of Plastic Mold CAD/CAE." Advanced Materials Research 503-504 (April 2012): 159–62. http://dx.doi.org/10.4028/www.scientific.net/amr.503-504.159.

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An Integrated System of Plastic Mold CAD/CAE for key parts of large scale plastic mold is established, which consists of the three subsystems the CAD subsystems, the CAE subsystems and the materials query subsystem. The functions of the integrated system are realized based on Visual Studio platform, by using SQL Server Database, Pro/E, Pro/TOOLKIT and ANSYS Optimum Design. The integrated system provides seamless integration functionality through sharing and exchange of the same parameters between the CAD subsystem and the CAE subsystem. The parameters of the parts are saved in the SQL Server in the integrated system of plastic mold CAD/CAE. Firstly, the parameters values can be identified by CAD primary design in the CAD subsystem; secondly, The CAE subsystem reads these parameters and gains the material parameters from the materials query subsystem. Then, the remote optimization is conducted in the CAE subsystem; lastly, the CAD subsystem obtains final parameters values from the CAE subsystem, according to the results of remote optimization

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10

Demirkol, Sait, Sevket Balta, Turgay Celik, Murat Unlu, Zekeriya Arslan, Mustafa Cakar, Ugur Kucuk, et al. "Carotid Intima Media Thickness and Its Association With Total Bilirubin Levels in Patients With Coronary Artery Ectasia." Angiology 71, no. 5 (January 27, 2013): 425–30. http://dx.doi.org/10.1177/0003319712473796.

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Atherosclerosis plays an important role in the etiopathogenesis of coronary artery ectasia (CAE). The relationship between total bilirubin (TBil) and carotid intima media thickness (cIMT) in patients with CAE has not been fully investigated. Hence, we evaluated the relationship between TBil levels and cIMT in 142 consecutive eligible patients with CAE, newly diagnosed coronary artery disease (CAD), and normal coronary arteries. There were no significant differences in TBil ( P = .772) and cIMT ( P = .791) between the CAE and CAD groups. Bilirubin levels were significantly lower in both CAE and CAD groups compared to the controls ( P < .01). The cIMT was significantly higher in both CAE and CAD groups compared to control participants ( P < .01). A negative correlation between cIMT and TBil was found in all the groups ( P < .01, r = .354). We show for the first time that patients with CAE and CAD have lower TBil and greater cIMT compared to controls with normal coronary angiograms.

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11

Ali, Nur Shidaa Mohd, Abu Bakar Salleh, Thean Chor Leow, Raja Noor Zaliha Raja Abd Rahman, and Mohd Shukuri Mohamad Ali. "The Influence of Calcium toward Order/Disorder Conformation of Repeat-in-Toxin (RTX) Structure of Family I.3 Lipase from Pseudomonas fluorescens AMS8." Toxins 12, no. 9 (September 9, 2020): 579. http://dx.doi.org/10.3390/toxins12090579.

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Calcium-binding plays a decisive role in the folding and stabilization of many RTX proteins, especially for the RTX domain. Although many studies have been conducted to prove the contribution of Ca2+ ion toward the folding and stabilization of RTX proteins, its functional dynamics and conformational structural changes remain elusive. Here, molecular docking and molecular dynamics (MD) simulations were performed to analyze the contribution of Ca2+ ion toward the folding and stabilization of the RTX lipase (AMS8 lipase) structure. AMS8 lipase contains six Ca2+ ions (Ca1–Ca6). Three Ca2+ ions (Ca3, Ca4, and Ca5) were bound to the RTX parallel β-roll motif repeat structure (RTX domain). The metal ion (Ca2+) docking analysis gives a high binding energy, especially for Ca4 and Ca5 which are tightly bound to the RTX domain. The function of each Ca2+ ion is further analyzed using the MD simulation. The removal of Ca3, Ca4, and Ca5 caused the AMS8 lipase structure to become unstable and unfolded. The results suggested that Ca3, Ca4, and Ca5 stabilized the RTX domain. In conclusion, Ca3, Ca4, and Ca5 play a crucial role in the folding and stabilization of the RTX domain, which sustain the integrity of the overall AMS8 lipase structure.

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12

Halpern, Mar. "Pushing the Design Envelope with CAE." Mechanical Engineering 120, no. 11 (November 1, 1998): 66–71. http://dx.doi.org/10.1115/1.1998-nov-2.

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This article examines the growing usefulness of computer-aided engineering (CAE) programs for the design of electronics packaging. CAE combined with expert interpretation, can help manufacturers quickly satisfy demand for increasingly small yet reliable products. Currently, three classes of software specifically support electronics packaging design: integrated computer-aided design (CAD) CAE software, general-purpose CAE software, and specialty CAE software solutions. The integrated CAE software emphasizes automatic creation and updating of finite-element-analysis (FEA) models based on CAD geometry. The effectiveness of this associativity between CAD and FEA depends on the product behavior to be evaluated and the quality of implementation. CAE simulation can calculate the maximum acceptable loads on pins, as well as the vibration characteristics of components. Solids-based CAD helps detect interference problems across components, as in these exploded views of a disc drive and a headset. While several general-purpose CAE suppliers permit engineers to build customized environments for automating model creation, specialty suppliers such as Pacific Numerix deliver the specific automated capabilities and connector libraries.

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13

Li, Shen, Xiao Dong Shao, and Xiao Bo Ge. "A Kind of CAD/CAE Integrated Modeling Technology Based on FEATURE." Advanced Materials Research 97-101 (March 2010): 3436–42. http://dx.doi.org/10.4028/www.scientific.net/amr.97-101.3436.

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A kind of CAD/CAE integrated modeling method based on feature is proposed. Firstly, analysis features are attached to CAD model of part and standard part library is formed. Secondly, the CAD model is created using standard parts. Thirdly, geometry information of analysis features is extracted from CAD model and is reconstructed automatically under CAE environment. Finally, based on feature-based meshing and combination technique, CAE model is built quickly. A prototype software for large-scale antenna structure (LSAS) CAD/CAE integrated modeling has been developed and used in performance analysis of a 16-meter-diameter LSAS. The method has been proved to be useful for improving speed, accuracy and consistency of complicated structure CAE modeling notably.

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14

Erkan, Hakan, Mustafa T. Ağaç, Seda Akyol, Levent Korkmaz, Abdulkadir Kiriş, Merve Erkan, Zeydin Acar, et al. "Coronary artery calcification score is increased in patients with isolated coronary artery ectasia." Clinical & Investigative Medicine 36, no. 4 (August 1, 2013): 191. http://dx.doi.org/10.25011/cim.v36i4.19952.

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Purpose: Coronary artery calcification (CAC) is an indicator of coronary atherosclerosis and is associated with future adverse cardiac events. Isolated coronary artery ectasia (CAE) is defined as localized or diffuse dilation of the coronary arteries without coronary stenosis. The aim of this study was to assess the relationship between CAC and isolated CAE. Methods: Thirty-four patients with isolated CAE and 50 controls subjects, with normal coronary arteries, were enrolled in the study. Baseline demographic features and atherosclerosis risk factors were similar in both groups. Results: Patients with CAE had higher total CAC than control subjects (84±111 vs. 33.5 ± 103.5; p < 0.001). There was also a significant correlation between per-segment CAC and ectatic segment length (r=0.32; p=0.01) but no correlation with diameter (r=0.09; p=0.5). Conclusion: Patients with isolated CAE had higher CAC than control subjects, suggesting that atherosclerosis may be involved in the pathogenesis of isolated CAE. Patients with isolated CAE may have increased cardiovascular risk and should receive appropriate risk stratification and relevant medical treatment.

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Richards, Gavin H. C., Kathryn L. Hong, Michael Y. Henein, Colm Hanratty, and Usama Boles. "Coronary Artery Ectasia; Review of the Non-Atherosclerotic Molecular and Pathophysiologic Concepts." International Journal of Molecular Sciences 23, no. 9 (May 6, 2022): 5195. http://dx.doi.org/10.3390/ijms23095195.

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Coronary artery ectasia (CAE) is frequently encountered in clinical practice, conjointly with atherosclerotic CAD (CAD). Given the overlapping cardiovascular risk factors for patients with concomitant CAE and atherosclerotic CAD, a common underlying pathophysiology is often postulated. However, coronary artery ectasia may arise independently, as isolated (pure) CAE, thereby raising suspicions of an alternative mechanism. Herein, we review the existing evidence for the pathophysiology of CAE in order to help direct management strategies towards enhanced detection and treatment.

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Chen, Tao. "Research on CAD/CAE Information Integrated System Based on Web Services." Applied Mechanics and Materials 220-223 (November 2012): 2740–45. http://dx.doi.org/10.4028/www.scientific.net/amm.220-223.2740.

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The information integrated plan based on Web services was proposed, in view of the informations in current CAD, CAE systems are heterogeneous, distributed and diversity. Combined with the CAD/CAE information integrated system to expound the realization process of Web Services. On the basis of overall analysis of the CAD/CAE information integrated system, provided the framework of information integrated system with PDM functions as the core, which based on Web services technology. The development of CAD/CAE information integrated system based on Web services offerrs a possibility for remote collaboration in a distributed enviorment.

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Shen, Yuan, Dong Cai Liu, Ya Lin Shen, and Chan Gan Zhu. "Research and Design on Universal Framework for Integration CAD / CAE System." Advanced Materials Research 211-212 (February 2011): 595–99. http://dx.doi.org/10.4028/www.scientific.net/amr.211-212.595.

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This paper, which studied the structure of CAD/ CAE system, has proposed a universal CAD / CAE integration framework. This system, with good compatibility and being convenient to be used, can be the basic platform for all CAD / CAE systems. This framework, with a unified structure of command processor, the message processing system, selection mechanism, can transform the development of CAD / CAE integrated system to that of functional command module. With the help of this framework, functional development no longer relies on framework. Therefore, the framework greatly enhances the efficiency of software system development.

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HAGIWARA, Ichiro. "341 Present Status and Future Prospect of CAD/CAE." Proceedings of The Computational Mechanics Conference 2006.19 (2006): 433–34. http://dx.doi.org/10.1299/jsmecmd.2006.19.433.

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Yılmaz, Mücahid, Hasan Korkmaz, Mehmet Nail Bilen, Ökkeş Uku, and Ertuğrul Kurtoğlu. "Could neutrophil/lymphocyte ratio be an indicator of coronary artery disease, coronary artery ectasia and coronary slow flow?" Journal of International Medical Research 44, no. 6 (November 10, 2016): 1443–53. http://dx.doi.org/10.1177/0300060516664637.

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Objective To determine whether neutrophil/lymphocyte ratio (NLR) differed between patients with isolated coronary artery disease (CAD), isolated coronary artery ectasia (CAE), coronary slow flow and normal coronary anatomy. Methods Patients who underwent coronary angiography were consecutively enrolled into one of four groups: CAD, coronary slow flow, CAE and normal coronary anatomy. Results The CAD ( n = 40), coronary slow flow ( n = 40), and CAE ( n = 40) groups had similar NLRs (2.51 ± 0.7, 2.40 ± 0.8, 2.6 ± 0.6, respectively) that were significantly higher than patients with normal coronary anatomy ( n = 40; NLR, 1.73 ± 0.7). Receiver operating characteristics demonstrated that with NLR > 2.12, specificity in predicting isolated CAD was 85% and sensitivity was 75%, with NLR > 2.22 specificity in predicting isolated CAE was 86% and sensitivity was 75%. With NLR > 1.92, specificity in predicting coronary slow flow was 89% and sensitivity was 75%. Multivariate logistic regression analyses identified NLR as an independent predictor of isolated CAE (β = −0.499, 95% CI −0.502, −0.178; P < 0.001), CAD (β = −0.426, 95% CI −1.321, −0.408; P < 0.001), and coronary slow flow (β = −0.430, 95% CI −0.811, −0.240; P = 0.001 Table 2 ). Conclusions NLR was higher in patients with CAD, coronary slow flow and CAE versus normal coronary anatomy. NLR may be an indicator of CAD, CAE and coronary slow flow.

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Toprak, Kenan, Mustafa Kaplangoray, and Ali Palice. "The Impact of C-Peptide and Diabetes Mellitus on Coronary Ectasia and Effect of Coronary Ectasia and C-Peptide on Long-Term Outcomes: A Retrospective Cohort Study." International Journal of Clinical Practice 2022 (October 8, 2022): 1–18. http://dx.doi.org/10.1155/2022/7910566.

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Background. Coronary artery ectasia (CAE) is an entity frequently associated with atherosclerotic coronary artery disease (CAD) in clinical practice. Although it has common risk factors with atherosclerotic CAD in its development, the pathophysiology of CAE is not fully known and it is not seen in every CAD suggesting that different determinants may play a pivotal role in the development of CAD. This study aimed to reveal the impact of C-peptide and diabetes mellitus (DM) on CAE and the effect of C-peptide and coronary ectasia on long-term outcomes in patients who underwent coronary angiography. Methods. A total of 6611 patients who underwent coronary angiography were followed up retrospectively, and their major adverse cardiovascular event (MACE) status of an average of sixty months was recorded. According to their angiographic features, the patients were divided into two groups those with and without CAE. MACE development was accepted as the primary endpoint. Results. A total of 552 patients had CAE and MACE developed in 573 patients. Patients with CAE and higher C-peptide levels (Q4 + Q3) showed higher rates of MACE as compared to those without CAE and lower C-peptide levels (Q1 + Q2) (20.8% vs 7.6%; 70.1% vs 29.1%; p < 0.001 , for both of them). In multivariate regression analysis, high C-peptide levels were determined as an independent risk factor for CAE (OR 2.417; 95% CI 2.212–2.641; p < 0.001 ). The Kaplan–Meier cumulative survival curves showed that the risks for MACE increased as the C-peptide levels increased. The Cox regression analysis for 5-years MACE related to the plasma C-peptide levels and presence of CAE, C-peptide, and CAE were found to be independent predictors of MACE (HR = 1.255, 95% CI: 1.164–1.336, p < 0.001 and HR = 1.012, 95% CI: 1.002–1.023, p = 0.026 , respectively). Conclusion. Our study revealed that a high C-peptide level is an independent risk factor for CAE and that CAE and C-peptide are independent predictors for the development of MACE.

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Liao, Dun Ming, Li Liang Chen, Jian Xin Zhou, and Rui Xiang Liu. "CAD/CAE Technology and its Application on Nonferrous Alloy Casting." Advanced Materials Research 139-141 (October 2010): 1113–16. http://dx.doi.org/10.4028/www.scientific.net/amr.139-141.1113.

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The nonferrous alloy castings will be much demanded with the development of aerospace, light-weight weapons and automotive industry. Casting CAD/CAE technology has played an increasingly important role in foundry. It can help technician to design casting process and simulate heat transferring and molten metal flowing before actual production. Firstly, the main contents and basic principles, mathematical models of casting CAD and CAE were introduced. Secondly, the casting CAD/CAE technology route was interpreted, and then several CAD/CAE applications of casting process design and simulating were carried out on nonferrous alloys, such as aluminum, magnesium and copper. The results indicate that CAD/CAE technology can be applied to casting process design and predict casting defects which usually occur during the casting mold filling and solidification process, it can provide references to optimize casting process, so as to improve casting quality, reduce the rejection rate and shorten the development cycle of new products.

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Yuan, Shi-Min. "Inflammatory mediators of coronary artery ectasia." Jornal Vascular Brasileiro 13, no. 3 (September 2014): 198–207. http://dx.doi.org/10.1590/jvb.2014.027.

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The exact mechanisms underlying coronary artery ectasia (CAE) remain uncertain. This study aims to investigate whether and how inflammatory mediators play a role in the pathogenesis of CAE. The data sources of this study were located by literature searches on MEDLINE, Highwire Press and Google search engine for the year range 2000-2013. The most sensitive of the four types of plasma inflammatory mediators were cell adhesion molecules and systemic inflammatory markers followed by cytokines, while proteolytic substances were the least sensitive indicators of CAE. Hypersensitive C-reaction protein, homocysteine, intercellular adhesion molecule 1, vascular cell adhesion molecule 1, matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-2, vascular endothelial growth factor and neopterin levels were significantly higher in CAE and coronary artery disease (CAD) patients than in controls without CAE. The percentage of granulocytes was higher in CAE, in comparison with individuals with normal coronary arteries. Polymerase chain reaction determination of angiotensin converting enzyme genotypes showed that the DD genotype was more prevalent in CAE patients than in CAD patients, while prevalence of the I allele was higher in CAD than in CAE patients. CAE is more a result of inflammatory processes than of extracellular matrix degradation, as demonstrated by investigations of plasma inflammatory mediators, activation markers and angiotensin converting enzyme genotypes. Contemporary theories are unable to explain CAE's predilection for the right coronary artery or the occurrence of multi-vessel and multi-segment involvement.

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Wang, Sha Na, Fu Yun Liu, Yun Ze Yang, Kun Xu, and Ning Jia. "Research on the Variant Design Method Based on the Integration of CAD/CAE." Applied Mechanics and Materials 224 (November 2012): 248–51. http://dx.doi.org/10.4028/www.scientific.net/amm.224.248.

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Component variant design method based on parametric design technology and parametric CAE technology are discussed. Based on the integration of CAD and CAE, a variant design method with the function to satisfy engineering constraints is put forward. Using VC++ and Jscript as developing tools, CAD system (SolidWorks) and CAE system (ANSYS) are redeveloped and integrated. A variant design method based on the integration of CAD/CAE is realized. A prototype system of the above variant design method is developed. As an example, variant design of workbench of a machine tool is realized. The variant design method and the variant design prototype system are verified.

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Shelar, Vaibhav, Selamani Subramani, and Jebaseelan Davidson. "R-tree data structure implementation for Computer Aided Engineering (CAE) tools." International Journal for Simulation and Multidisciplinary Design Optimization 12 (2021): 6. http://dx.doi.org/10.1051/smdo/2021005.

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Searching and handling geometric data are basic requirements of any Computer Aided Engineering application (CAE). Spatial search and local search has greater importance in CAD and CAE applications for reducing the model preparation time. There are many efficient algorithms being made to search geometrical data. Current neighbour search strategy is limited and not efficient in different CAE platforms. R-tree is tree data structure used for spatial access methods. This paper presents a review of R-tree data structure with its implementation in one of the CAE tool for neighbour search and local search. It satisfies current neighbour search requirements in CAE tools. Results shows considerable amount of time saving compared to the conventional approach. This work concludes that R-tree implementation can be helpful in identifying neighbour part and reducing model preparation time in CAD and CAE tools.

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Wang, Cheng, Xiong Wei Yang, and Bao Kun Yang. "Problems in the Application of Commercial CAD/CAE Software and Improvement Methods." Advanced Materials Research 201-203 (February 2011): 36–39. http://dx.doi.org/10.4028/www.scientific.net/amr.201-203.36.

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CAD / CAE technology has led traditional product design and analysis to digital. However, commercial CAD / CAE software also has its problems. Problems in the application of commercial CAD / CAE software are summarized in these this paper. From perspective development of software engineer, new technology such as integrated design, design reuse, intelligence and automation, workflow customization, application development, experimental and simulation complement each other are introduced to overcome these problems in this paper.

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Zhao, Yu. "Based on the CAD / CAE Technology Product Simulation Design System." Advanced Materials Research 479-481 (February 2012): 186–89. http://dx.doi.org/10.4028/www.scientific.net/amr.479-481.186.

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The paper analyze the existing CAD / CAE methods and differences in product design requirements. It points out that firstly, performance analysis and design is the core of mechanical product design; Secondly, integrated CAD / CAE technology, product design should be based on CAE-centric the design process. It proposes simulation-based design methods and constructs a performance-oriented product design system.

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Merkel, M., and A. Schumacher. "An Automated Optimization Process for a CAE Driven Product Development." Journal of Mechanical Design 125, no. 4 (December 1, 2003): 694–700. http://dx.doi.org/10.1115/1.1631570.

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Within the product development the need for generating design variants is given in many situations, for example to optimize an existing initial design with respect to new or modified requirements. For an efficient process it is essential that these variations can be done very easily within a small timeframe. In the virtual product development the physical characteristic of a component is determined by numerical simulation. Commercial software products exist for nearly each physical phenomenon. Often these methods are covered under CAE. A fundamental issue for building and analyzing variants easily and fast is a seamless interaction between the CAD and CAE software tools. This paper presents a powerful CAD/CAE sequence to the engineer’s community, where in contrast to other approaches results of the CAE analysis directly interact with CAD data. This strategy is supported by describing the product’s geometry by parameters. The CAD/CAE sequence is integrated in an optimization loop. The presented application example is an automotive part.

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Vinodh, S., and D. Kuttalingam. "Computer‐aided design and engineering as enablers of agile manufacturing." Journal of Manufacturing Technology Management 22, no. 3 (March 15, 2011): 405–18. http://dx.doi.org/10.1108/17410381111112747.

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PurposeThe purpose of this paper is to investigate computer‐aided design (CAD) and computer‐aided engineering (CAE) as enablers of agile manufacturing (AM).Design/methodology/approachBased on the literature review, the importance of technology integration enabling AM has been found. CAD technology has been used for modelling baseline product; CAE has been used for deriving optimized parameters; new designs have been derived.FindingsThe feasibility of CAD and CAE as enablers of AM has been ensured.Research limitations/implicationsThe study has been conducted only in one automotive sprocket manufacturing organization.Practical implicationsThe practical feasibility of generating new products through technology integration has been ensured.Originality/valueVery little research has been reported on technology‐integrated AM practices. In this study, CAD and CAE have been used for enabling product development.

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Pan, Zhiyi, Xin Wang, Rumin Teng, and Shunde Gao. "A Synchronous CAD/CAE Modeling Method and Applications in Parametric Parts Library." Open Mechanical Engineering Journal 9, no. 1 (April 17, 2015): 189–95. http://dx.doi.org/10.2174/1874155x01509010189.

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Current parametric parts library cannot contribute to the reuse of finite element model. It is essential to remodel or exchange model for parts in CAE software. This paper presents a synchronous CAD/CAE modeling method, which can be employed in parts library based on Siemens NX software. Primary CAD and CAE information in part are merged into master model, which acts as cornerstone for solid model, FE model and simulation model. Thus, part models from parts library can be directly used into simulation analysis, and parametric amendment and change propagation is sustained. A software package developed for designers is helpful to search and achieve desired part from parts library. Three case studies are carried out to clarify synchronous CAD/CAE modeling process and change propagation procedure.

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Kshyvetskyy, B. Ya, and V. R. Solonynka. "ІМІТАЦІЙНЕ МОДЕЛЮВАННЯ ТЕРМОПЛАСТИЧНИХ КЛЕЙОВИХ З'ЄДНАНЬ ДЕРЕВИНИ В CAD/CAE СИСТЕМАХ." Scientific Bulletin of UNFU 25, no. 8 (October 29, 2015): 215–21. http://dx.doi.org/10.15421/40250836.

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Наведено результати імітаційного моделювання термопластичних полівінілацетатних клейових з'єднань деревини з використанням CAD/CAE систем. Розроблено алгоритм імітаційного моделювання в CAD/CAE системах напружено-деформаційного стану термопластичних клейових з'єднань деревини залежно від зміни температури та вологості. Доповнено бібліотечну базу даних CAD/CAE систем фізико-механічними та фізико-хімічними характеристиками різних порід деревини та клейовими матеріалами на термопластичній основі. Розроблений алгоритм імітаційного моделювання та сформована база даних дає змогу моделювати зміну вологості, температури та напружено-деформаційного стану у будь-якій точці термопластичного клейового з'єднання деревини залежно від зміни вологості та температури.

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Dereli, Seçkin, İdris Buğra Çerik, Ahmet Kaya, and Osman Bektaş. "Assessment of the Relationship Between C-Reactive Protein-to-Albumin Ratio and the Presence and Severity of Isolated Coronary Artery Ectasia." Angiology 71, no. 9 (June 10, 2020): 840–46. http://dx.doi.org/10.1177/0003319720930983.

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We investigated the relationship between C-reactive protein-to-albumin ratio (CAR) and coronary artery ectasia (CAE). The retrospective study population included 150 patients with isolated CAE, 150 with obstructive coronary artery disease (CAD), and 150 with a normal coronary artery angiogram (NCA). The severity of isolated CAE was determined according to the Markis classification. C-reactive protein-to-albumin ratio was significantly higher in patients with isolated CAE than in those with obstructive CAD and NCA (10.5 [5.9-30.9], 5.7 [1.8-13.2] and 3.0 [0.9-8.9], respectively). Logistic regression analysis showed that CAR (odds ratio [OR]: 3.054, 95% CI: 1.021-9.165, P = .001), platelet-to-lymphocyte ratio (PLR; OR: 1.330, 95% CI: 1.025-1.694, P = .044), and monocyte-to-high density cholesterol ratio (MHR; OR: 1.031, 95% CI: 1.009-1.054, P = .006) were independently associated with the presence of isolated CAE. Receiver operating characteristic curve analysis showed that CAR (area under the curve [AUC] ± standard error [SE] = 0.838 ± 0.016; P < .001) had a stronger diagnostic value for detecting significant CAE than PLR (AUC ± SE = 0.632 ± 0.023) and MHR (AUC ± SE = 0.726 ± 0.022). C-reactive protein-to-albumin ratio had a significantly strong correlation with the severity of isolated CAE (r = 0.536, P < .001). To the best of our knowledge, this study showed for the first time that CAR was significantly associated with CAE presence and severity.

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Li, Qing, Li Dai, Zhi Gao Huang, and Hua Min Zhou. "The Design and Implementation of a CAD/CAE Integrated System for Plastic Injection Molding." Advanced Materials Research 314-316 (August 2011): 1287–94. http://dx.doi.org/10.4028/www.scientific.net/amr.314-316.1287.

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In the plastic injection molding process, interaction between design and analysis is very intensive. However, current computer-aided systems (CAD and CAE) are realized as isolated modules. Thus, designers need to transform data models between CAD and CAE systems. Defects of many data errors and duplicated work are inevitable. This paper presents a CAD/CAE integrated system, building on top of existing CAD and CAE systems. The framework of the system is designed. A parametric integration model is established to achieve bidirectional association between the two systems. Details of key technologies in pre- and post- processing are discussed, such as mesh generation, feature recognition, and automatic evaluation of analysis results. A practical engineering case is studied to illustrate that the system can effectively avoid mesh repair and remodeling in pre-processing, reduce the dependency on experience in analysis result evaluation, and greatly improve the efficiency of iterative design-analysis-optimization process.

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Yokoyama, Atsushi. "CAE." Seikei-Kakou 23, no. 7 (June 20, 2011): 409–13. http://dx.doi.org/10.4325/seikeikakou.23.409.

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Yokoyama, Atsushi. "CAE." Seikei-Kakou 22, no. 7 (June 20, 2010): 353–57. http://dx.doi.org/10.4325/seikeikakou.22.353.

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Seto, Masahiro. "CAE." Seikei-Kakou 22, no. 9 (August 20, 2010): 468_1. http://dx.doi.org/10.4325/seikeikakou.22.468_1.

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Seto, Masahiro. "CAE." Seikei-Kakou 21, no. 9 (August 20, 2009): 518_2. http://dx.doi.org/10.4325/seikeikakou.21.518_2.

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Nakayama, Yasuya. "CAE." Seikei-Kakou 21, no. 7 (June 20, 2009): 385–88. http://dx.doi.org/10.4325/seikeikakou.21.385.

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Aoki, Gen, and Hiroki Otsuka. "CAE." Seikei-Kakou 15, no. 7 (July 20, 2003): 468–71. http://dx.doi.org/10.4325/seikeikakou.15.468.

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Shimomai, Ken. "CAE." Seikei-Kakou 17, no. 7 (July 20, 2005): 448–50. http://dx.doi.org/10.4325/seikeikakou.17.448.

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Yasuda, Takeshi, and Shuichi Tanoue. "CAE." Seikei-Kakou 18, no. 7 (July 20, 2006): 468–71. http://dx.doi.org/10.4325/seikeikakou.18.468.

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Nakayama, Yasuya. "CAE." Seikei-Kakou 20, no. 7 (July 20, 2008): 405–8. http://dx.doi.org/10.4325/seikeikakou.20.405.

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Yasuda, Takeshi. "CAE." Seikei-Kakou 19, no. 7 (July 20, 2007): 409–12. http://dx.doi.org/10.4325/seikeikakou.19.409.

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Seto, Masahiro. "CAE." Seikei-Kakou 24, no. 9 (August 20, 2012): 511. http://dx.doi.org/10.4325/seikeikakou.24.511.

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Seto, Masahiro. "CAE." Seikei-Kakou 25, no. 10 (September 20, 2013): 452_2. http://dx.doi.org/10.4325/seikeikakou.25.452_2.

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Taniguchi, Takashi. "CAE." Seikei-Kakou 26, no. 5 (April 20, 2014): 210_2. http://dx.doi.org/10.4325/seikeikakou.26.210_2.

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Kushizaki, Yoshiyuki. "CAE." Seikei-Kakou 26, no. 7 (June 20, 2014): 331–33. http://dx.doi.org/10.4325/seikeikakou.26.331.

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Okada, Yuji. "CAE." Seikei-Kakou 26, no. 11 (October 20, 2014): 505. http://dx.doi.org/10.4325/seikeikakou.26.505.

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Yamanoi, Mikio. "CAE." Seikei-Kakou 27, no. 5 (April 20, 2015): 165_1. http://dx.doi.org/10.4325/seikeikakou.27.165_1.

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Kushizaki, Yoshiyuki. "CAE." Seikei-Kakou 27, no. 7 (June 20, 2015): 275–79. http://dx.doi.org/10.4325/seikeikakou.27.275.

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Yamanoi, Mikio. "CAE." Seikei-Kakou 28, no. 7 (June 20, 2016): 275–78. http://dx.doi.org/10.4325/seikeikakou.28.275.

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