Academic literature on the topic 'C1 Complex'

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Journal articles on the topic "C1 Complex"

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Guiot, Bernard, and Richard G. Fessler. "Complex atlantoaxial fractures." Journal of Neurosurgery: Spine 91, no. 2 (October 1999): 139–43. http://dx.doi.org/10.3171/spi.1999.91.2.0139.

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Object. The authors conducted a retrospective study to evaluate the treatment of complex C1–2 fractures. Methods. There were 10 cases of complex C1–2 fractures. Six patients were men (median age 58 years) and four patients were women (median age 55.5 years). Injuries resulted from seven falls, two motor vehicle accidents, and one diving incident. Three patients suffered from upper-extremity weakness. Neurological function in seven patients was intact preoperatively. Fracture combinations included six Jefferson/Type II odontoid, two anterior ring/Type II odontoid, one posterior ring/Type II odontoid, and one posterior ring/Type III odontoid/Type III hangman's fracture. All patients underwent surgery, five after halo immobilization for an average of 4 months failed to provide stability. Treatment included placement of six odontoid screws, one posterior C1–2 transarticular screw, one odontoid screw with anterior C1–2 transarticular screw fixation, one C1–2 transarticular screw with C1–2 Songer cable fusion, and one odontoid screw with bilateral C-2 pedicle screw fixation. Specific treatment was determined by the combination of fractures. Postoperatively, all patients were immobilized in a hard collar for 3 months. There were no intraoperative surgery-related complications. The mean follow-up period was 28.5 months. Neurological recovery was observed in one of three patients who presented with neurological deficits. Fusion occurred in all cases. Conclusions. The goals in treating these complex fractures are to achieve early maximum stability and minimum reduction in range of motion. These are often competing phenomena. Frequently in cases of atlas—axis fracture, odontoid screw fixation combined with hard collar immobilization is the best therapy, provided the transverse atlantal ligament is competent. If not, C1–2 stabilization with placement of transarticular screws is required for best results.
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Colomb, Maurice, and Gérard Arlaud. "C1 complex of human complement." Journal of Molecular Biology 195, no. 2 (May 1987): 435. http://dx.doi.org/10.1016/0022-2836(87)90662-0.

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Mortensen, Simon A., Bjørn Sander, Rasmus K. Jensen, Jan S. Pedersen, Monika M. Golas, Steffen Thiel, and Gregers R. Andersen. "Models of the complement C1 complex." Proceedings of the National Academy of Sciences 115, no. 17 (April 13, 2018): E3866. http://dx.doi.org/10.1073/pnas.1803577115.

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Weiss, V., and J. Engel. "Functional models of the C1 complex." Journal of Molecular Biology 195, no. 2 (May 1987): 437–38. http://dx.doi.org/10.1016/0022-2836(87)90663-2.

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Levine, Alan M., Jeffrey Fischgrund, and Charles Edwards. "Fractures of the C1–2 Complex." Journal of Orthopaedic Trauma 7, no. 2 (April 1993): 172. http://dx.doi.org/10.1097/00005131-199304000-00053.

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Vilela, Marcelo D., Charles Jermani, and Bruno P. Braga. "C1 lateral mass screws for posterior segmental stabilization of the upper cervical spine and a new method of three-point rigid fixation of the C1-C2 complex." Arquivos de Neuro-Psiquiatria 64, no. 3b (September 2006): 762–67. http://dx.doi.org/10.1590/s0004-282x2006000500012.

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OBJECTIVE: To describe our experience with C1 lateral mass screws as part of a construct for C1-2 stabilization and report an alternate method of C1-C2 complex three-point fixation. METHOD: All patients that had at least one screw placed in the lateral mass of C1 as part of a construct for stabilization of the C1-C2 complex entered this study. In selected patients who had a higher chance of nonunion an alternate construct was used: transarticular C1-C2 screws combined with C1 lateral mass screws. RESULTS: Twenty-one C1 lateral mass screws were placed in 11 patients. In three patients the alternate construct was used. All patients had a demonstrable solid and stable fusion on follow-up. CONCLUSION: C1 lateral mass screws are safe and provide immediate stability. The use of C1-C2 transarticular screws combined with C1 lateral mass screws is a feasible and also an excellent alternative for a three-point fixation of the C1-C2 complex.
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GOEL, VIJAY K., JOHN M. WINTERBOTTOM, KARYR SCHULTE, HAN CHANG, LARS G. GILBERTSON, ARTHUR G. PUDGIL, and JONG K. GWON. "Ligamentous Laxity Across C0-C1-C2 Complex." SPINE 15, no. 10 (October 1990): 990–96. http://dx.doi.org/10.1097/00007632-199010000-00002.

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GOEL, VIJAY K., JOHN M. WINTERBOTTOM, KARYR SCHULTE, HAN CHANG, LARS G. GILBERTSON, ARTHUR G. PUDGIL, and JONG K. GWON. "Ligamentous Laxity Across C0-C1-C2 Complex." SPINE 15, no. 10 (October 1990): 990–96. http://dx.doi.org/10.1097/00007632-199015100-00002.

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Arlaud, Gérard J., Christine Gaboriaud, Wai Li Ling, and Nicole M. Thielens. "Structure of the C1 complex of complement." Proceedings of the National Academy of Sciences 114, no. 29 (July 12, 2017): E5766—E5767. http://dx.doi.org/10.1073/pnas.1703977114.

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ARLAUD, GÉRARD J., NICOLE M. THIELENS, and CHANTAL ILLY. "Arrangement of the C1 complex of complement." Biochemical Society Transactions 18, no. 6 (December 1, 1990): 1148–51. http://dx.doi.org/10.1042/bst0181148.

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Dissertations / Theses on the topic "C1 Complex"

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Alnagi, Omar. "Reaction de la trimethylphosphine sur les sels de cobalt (ii) : synthese des complexes pentacoordonnes cox::(2)(pme::(3))::(3) (x=c1**(-), br**(-), i**(-), ncs**(-), no::(2)**(-)), reactivite vis-a-vis de petites molecules co, no et o::(2)." Toulouse 3, 1987. http://www.theses.fr/1987TOU30048.

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Synthese et etude physicochimique des complexes. Reactivite. Etude cristallographique de la structure indiquant une geometrie de bipyramide trigonale deformee quand x**(-)=cl**(-),br**(-),i**(-),ncs**(-) et une geometrie de pyramide a base carree pour x=no::(2)**(-). Etude des substitutions par co,no et o::(2)
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Baer, Kimberly Kay. "Protein Coevolution and Coadaptation in the Vertebrate bc1 Complex." Diss., CLICK HERE for online access, 2007. http://contentdm.lib.byu.edu/ETD/image/etd1994.pdf.

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Hunt, Jamie. "C1- and C2- Symmetrical Metal-Salen Complexes and their Application to Asymmetric Catalysis." Thesis, University of Newcastle Upon Tyne, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515075.

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Mann, Tyler J. "Stereoselective Olefin Metathesis Reactions Catalyzed by Molybdenum Monoaryloxide Monopyrrolide Complexes." Thesis, Boston College, 2016. http://hdl.handle.net/2345/bc-ir:104995.

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Thesis advisor: Amir H. Hoveyda
Chapter 1: Efficient Z-Selective Cross-Metathesis of Secondary Allylic Ethers Efficient Z-selective cross-metathesis of secondary allylic ethers were catalyzed by monoaryloxide monopyrrolide molybdenum complexes. Reactions involving both silyl and benzyl protected ethers were demonstrated, as well as ethers containing alkyl, aryl and alkynyl substituents. Mechanistic studies were performed, and the reactions were applied to the total synthesis of several ene-diyne natural products. Chapter 2. Stereoselective Total Synthesis of Disorazole C1 The stereoselective total synthesis of disorazole C1 is reported. The synthesis was completed in 12 longest linear steps. Our synthesis demonstrates the utility of Z-selective cross-metathesis to form both alkenyl borons and alkenyl halides. Another key transformation was a one-pot Suzuki-dimerization reaction to form a symmetric 30 membered ring in relatively high yield. Chapter 3. Stereoselective Cross-Metathesis to Form Trisubstituted Alkenes Initial studies into the stereoselective formation of trisubstituted olefins through molybdenum catalyzed cross-metathesis have been performed. Our mechanistic understanding of the reaction lead us to focus on the synthesis of alkenyl halides, which can be obtained in up 90% yield and 75:25 E:Z selectivity. Chapter 4: Ring-Closing Metathesis in the Synthesis of Natural Products Development of highly efficient and selective ring-closing metathesis reactions have enabled collaborators to successfully implement routes in total synthesis endeavors. A diastereoselective seven-membered ring-closing metathesis enabled the successful synthesis of (±)-tetrapetalone A methyl-aglycon. An enantioselective ring-closing metathesis to form a six membered ring has provided access to enantioenriched aspidosperma alkaloids
Thesis (PhD) — Boston College, 2016
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Chemistry
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Illy, Chantal. "Structures et mécanismes impliqués dans l'assemblage et l'activation du complexe C1 de la voie classique du complément humain." Grenoble 1, 1992. http://www.theses.fr/1992GRE10152.

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Le complexe c1 du systeme complementaire humain est une protease multimoleculaire (comprenant 2 sous-unites, c1q et c1s-c1r-c1r-c1s), dont l'activation declenche la cascade proteolytique de la voie classique du complement. Le travail presente dans cette these a pour objet la caracterisation des sites responsables des interactions ca#2#+-dependantes c1s/c1s, c1r/c1s et c1q/c1s-c1r-c1r-c1s, et des mecanismes d'activation de c1. L'iodation catalysee par la lactoperoxydase de c1s sous ses formes monomere et dimere a permis de definir plus precisement les portions de c1s impliquees dans sa dimerisation. Cette etude nous a egalement permis de proposer un modele des 2 types d'interaction ca#2#+-dependantes c1s/c1s et c1r/c1s. Par l'approche des modifications chimiques specifiques de certains residus, nous avons montre que l'assemblage du complexe c1 implique une interaction ionique majeure entre les residus basiques (probablement des lysines) de c1q localises dans sa region de type collagene et partage par au moins 2 chaines, et des residus acides du tetramere localises dans c1r. L'etude du mecanisme d'activation de c1 apprehende par differentes approches a montre que: les tetes globulaires de c1q jouent un role indirect important dans l'activation de c1, les domaines catalytiques de c1s ne sont pas necessaires a l'activation de c1, des residus lysine des domaines catalytiques de c1r sont impliques dans son mecanisme d'autoactivation et des residus acides de c1r interviennent dans la regulation de son autoactivation exercee par le ca#2#+. Consideres dans leur ensemble, ces resultats permettent d'affiner le modele structural et fonctionnel de c1, propose par le laboratoire en 1984
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Procter, Martin James. "Nucleophilic addition to #pi#-allyl molybdenum complexes : a synthesis of the C1-C9 fragment of salinomycin." Thesis, University of Southampton, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243118.

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Bernadet, Philippe. "Propriétés spectroscopiques de complexes formés entre un hydracide (HC1, HBr, HI) et l'oxyde d'ethylène (EO) en matrice d'argon et d'azone analyse du profil de la bande d'absorption HC1 des complexes H(D)C1, EO et H(D)C1." Grenoble 2 : ANRT, 1986. http://catalogue.bnf.fr/ark:/12148/cb375959760.

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Maceno, Marcelo Adriano Corrêa. "Resíduo de palma como substrato para a produção do complexo enzimático celulolítico - Subprojeto C1 projeto BIOPAL - Vale S. A." reponame:Repositório Institucional da UFPR, 2014. http://hdl.handle.net/1884/37847.

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Orientadora : Profa. Dra. Michele Rigon Spier
Co-orientador : Prof. Dr. Carlos Ricardo Soccol
Co-orientadora : Profª. Dra. Luciana Porto de Souza Vandenberghe
Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Tecnologia, Programa de Pós-Graduação em Engenharia de Bioprocessos e Biotecnologia. Defesa: Curitiba, 14/05/2014
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Área de concentração: Agroindústria e biocombustíveis
Resumo: Complexos celulolíticos são compostos por três tipos de celulases: endoglucanases, exoglucanases e ?-glicosidases. Industrialmente os fungos mais utilizados para a produção de celulases são o Trichoderma reesei e o Aspergillus niger, utilizando processo de fermentação submersa com sólido em suspensão (FSS), sendo que há poucas indústrias que utilizam resíduos para a produção desse complexo enzimático. As celulases possuem aplicação na indústria de alimentos, têxtil, de papel e celulose, na produção de biocombustíveis, entre outras aplicações. Este trabalho, um subprojeto da Projeto BioPal (Vale S.A), teve como objetivo a seleção de microrganismos, otimização da produção, concentração do produto e aumento de escala, para produção de celulases a partir de resíduo de palma. Neste trabalho foram testadas linhagens de Trichoderma sp., Aspergillus niger, Phanerochaete sp., Ganoderma sp. e Lentinus sp. para a produção de enzimas celulolíticas, usando resíduo de cacho de fruto vazio de palma como substrato em Fermentação submersa com sólidos suspensos. Com o fungo Phanerochaete sp obteve-se maior produção de celulases, porém, este fungo é conhecido por ser um bom produtor de enzimas ligninolíticas. A máxima produção de celulases foi alcançada no 4? dia de fermentação a 28 ?C, pH 5.7, com o fungo Phanerochaete sp., atingindo valores de atividade de FPase de 364 IU/L (aumento de 296 % em relação à atividade após a escolha da fonte de nitrogênio) e CMCase de 2864 IU/L (aumento de 180 % em relação à atividade após a escolha da fonte de nitrogênio), utilizando o resíduo sólido de palma (cacho de fruto vazio) como fonte de carbono. A granulometria do resíduo sólido de palma utilizado foi entre 0,35 mm e 0,85 mm e concentração de 15 g/L, ureia como fonte de nitrogênio (2 g/L), KH2PO4 (4 g/L), celulose microcristalina avicel como indutor (2 g/L) e utilizando a fermentação submersa com sólidos suspensos. Com esse trabalho pode-se verificar a produção do complexo celulolítico Phanerochaete sp. (PH-HD), abrindo espaço para novos estudos utilizando este fungo, para o qual não há muitos relatos na literatura, na produção do complexo celulolítico. Palavras-chave: palma, celulase, Phanerochaete, fermentação submersa
Abstract: Cellulolytic complex are enzymes that are composed of three cellulases: endoglucanases, exoglucanases and ?-glucosidades. Industrially, the most used fungi for the production of cellulases, are Trichoderma reesei and Aspergillus niger, using submerged fermentation, and there are just a few industries that use residues to the enzyme production. Cellulases are applicable in the food, textile, pulp and paper industries, biofuel, among other applications. This work, a subproject of the Project Biopal (Vale S.A) had, like objective, the screening of microorganisms, optimization of the production, product concentration and scaleup of the process, to production of cellulases using palm residue as substrate. In this work the strains Trichoderma sp., Aspergillus niger, Phanerochaete sp., Ganoderma sp. and Lentinus sp. were tested for cellulases complexes production under SFFs. Phanerochaete sp. (PH-HD) presented higher capacity of cellulases production, although this fungi is known to be a producer of lignolytic enzymes. The higher production of cellulases was achieved in the 4th day of fermentation, at 28 ?C, pH 5.7, with the fungi Phanerochaete sp., reaching values of FPase activity of 364 IU L-1 (an increase of 296 % related to the activity after the choice of the nitrogen source) and CMCase of 2864 IU L-1 (an increase of 180 % related to the activity after the choice of the nitrogen source), using palm residue (empty fruit bunch) as carbon source. The granulometry of the palm residue used was betweenm0,35 mm e 0,85 mm and 15 g/L of concentration,under SFFs using palm residue as carbon source, urea as nitrogen source (2 g/L), KH2PO4 (4 g/L), microcrystalline cellulose avicel as inducer (2 g/L) . With this work the cellulolytic complex production was verified with Phanerochaete sp., opening new studies using this fungi, which is not a lot related in the literature. Key words: palma, cellulase, Phanerochaete, Submerged fermentation.
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Rossi, Véronique. "Structure et fonction d'une protéase modulaire : étude de la région catalytique de la sous-unité C1s du complexe C1 du complément humain." Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10033.

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La sous-unite catalytique du complexe c1 du systeme complementaire humain est un tetramere ca#2#+-dependant (c1s-c1r-c1r-c1s) constitue de deux proteases a serine modulaires homologues, c1s et c1r. La protease c1s (673 acides amines, pm 79800), activee par c1r a la suite de la fixation de c1q a un activateur, declenche la voie classique du complement, par proteolyse de ses substrats c4 et c2. La proteolyse limitee de c1s par la plasmine produit le fragment catalytique gammab (270-673) constitue de deux modules ccp (complement control protein repeat) contigus, 4 et 5 (environ 60 residus chacun), d'un segment intermediaire (15 residus) et d'un domaine protease a serine (251 residus). Le travail presente dans cette these se situe dans le cadre de l'etude des relations structure-fonction de la protease c1s et a pour objectifs principaux: (i) l'etude de l'assemblage de la region catalytique de c1s, (ii) l'etude de l'implication des modules ccp 4 et 5 non proteasiques dans la proteolyse de ses substrats naturels, c4 et c2. Dans un premier temps, nous avons elabore un modele tridimensionnel de l'agencement des modules ccp 4, 5, du segment intermediaire et du domaine protease a serine. Une deuxieme partie du travail a consiste a verifier les hypotheses emises a l'aide du modele 3d, selon lesquelles les deux modules ccp 4 et 5, non proteasiques, confereraient a la protease c1s, sa haute specificite vis-a-vis du substrat c4. Cette partie du travail a egalement ete focalisee sur l'etude des regions de c1s impliquees dans la reconnaissance du deuxieme substrats de c1s, c2, pour lequel nous n'avons aucune indication. Deux fragments tronques de la region catalytique gammab de c1s, correspondant a une deletion du module ccp 4 seul, ou des deux modules ccp 4 et 5, ont ete produits sous forme proenzyme, dans un systeme eucaryote, cellules d'insecte sf21/baculovirus, en utilisant le systeme bac-to-bac#t#m. Nous avons montre que le fragment 5-b est activable par c1r de la meme maniere que c1s intact. Nous avons egalement montre que les informations necessaires pour la proteolyse de c2 sont toutes contenues dans le fragment 5-b tandis que certains elements de reconnaissance de c4 sont contenus dans le module ccp 4
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Stephens, Susanna Louise. "Investigations of non-covalent interactions : microwave spectroscopy of halogen-bonded complexes B...CF3I and metal-containing complexes C2Hn...M-C1, (n=2 or 4, M=Cu or Ag)." Thesis, University of Bristol, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.684746.

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Microwave spectroscopy allows study of the bond lengths and angles of molecules and molecular complexes. Gas phase molecules are exposed to microwave radiation while entrained within a molecular beam. The observed microwave spectrum can be used to calculate the physical dimensions of the molecules being excited. This thesis primarily discusses the building and modification of a chirped-pulse Fourier transform microwave (CP-FTMW) spectrometer and its use in conjunction with an established Balle-Flygare Fourier transform microwave (BF-FTMW) spectrometer in order to efficiently record and assign spectra. The CP-FTMW spectrometer was built and extensively used to observe spectra in the 6.5-19 GHz range. It is possible to measure a spectrum in one day using this spectrometer when it would require many weeks of manual measurements on the BF-FTMW spectrometer to do so. This thesis will explore weakly-bound complexes involving two subunits, the first being a Lewis base such as ethene, ethyne, ammonia or carbon monoxide, and the second an electron acceptor such as the iodine in CF3I, or the metal in the metal halides, AgCl or CuCl. These weakly bound molecular complexes present an opportunity to examine the fundamental interactions between the electron donor of the Lewis base molecules and the electron acceptor of the partner molecule. Five molecular complexes in their ground rotational state consisting of CF3I bonding to various Lewis bases have been investigated. These weakly bound complexes in the form CF3I ·· . B have the structure of a C3v molecule. Under this treatment CF3I··· Kr, CF3I··· CO, CF3I··· NH3, CF3I···N(CH3)3 and CF3I···PH3 have been found to have quartic force constants, kδ of between 3 and 12 Nm-1. The complexes CF3I···NH3, CF3I···N(CH3)3 and CF3I··· PH3 have been found to display evidence for internal rotation of the smaller Lewis base subunits with respect to the heavier CF3I subunit on the C3 axis of symmetry. These are assigned as A and E states, to which the internal rotation quantum number m transitions correspond to m = 0 and m = ±1 respectively. Several complexes in the form C2Hn···M - Cl where n = 2 or 4 and M = Cu or Ag. These molecules are found to have planar C2v symmetry.
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Books on the topic "C1 Complex"

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Huang, Jinfan. Gaseous electron-diffraction investigations: I. Molecular structures of Os(CO)₅, Ru(CO)₅, and CrOF₄. II. Molecular structures and anti-gauche compositions of BrCH₂,CH₂,F, BrCH₂CH₂C1, C1CH₂CH₂F,C1₂CHCHC1₂, and FCH₂CH₂OH. 1989.

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Book chapters on the topic "C1 Complex"

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Weinberg, Alvin M. "Nuclear energy and the agro-industrial complex." In ASA Special Publications, 1–14. Madison, WI, USA: American Society of Agronomy, 2015. http://dx.doi.org/10.2134/asaspecpub14.c1.

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Lorusso, M., T. Cocco, and D. Boffoli. "The Mitochondrial b-c1 Complex: Polypeptide Composition and Enzymatic Activities." In Organelles in Eukaryotic Cells, 209–18. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4613-0545-3_15.

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Gabellini, Nadia A. "Structural Homologies in the Cytochrome B/C1 Complex from Rhodobacter." In Cytochrome Systems, 35–40. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1941-2_4.

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Nałȩcz, M. J., and A. Azzi. "Functional Reconstitution of the Mitochondrial Cytochrome b-c1 Complex: Effect of Cholesterol." In Membrane Proteins, 151–59. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71543-3_16.

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Papa, S., F. Guerrieri, M. Lorusso, and D. Boffoli. "Mechanism of Proton Translocation by the b-c1 Complex of Mitochondrial Respiratory Chain." In Water and Ions in Biological Systems, 549–57. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4899-0424-9_53.

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Boffoli, D., M. Lorusso, and S. Papa. "Effect of Antimycin on the Kinetics of Reduction of b and c1 Cytochromes in Single Turnover of the Mitochondrial b-c1 Complex." In Cytochrome Systems, 669–71. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1941-2_91.

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Arrabaça, João Daniel, and Ana Maria Tenreiro. "The Effects of Inhibitors of the B-C1 Complex on the Respiration of Mitochondria from Aged Potato Discs." In Plant Mitochondria, 85–88. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4899-3517-5_11.

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Solaini, G., M. Crimi, F. Ballester, M. Degli Esposti, and G. Lenaz. "The Circular Dichroism Properties of the Rieske Protein and the b and c1 Cytochromes of the Mitochondrial bc1 Complex." In Cytochrome Systems, 337–38. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1941-2_44.

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Cocco, T., S. Meinhardt, D. Gatti, M. Lorusso, T. Ohnishi, and S. Papa. "Effects of Proteolytic Digestion and Chemical Modification of b-c1 Complex on the Fe-S Center and the Stable Ubisemiquinone (SQc)." In Cytochrome Systems, 559–60. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4613-1941-2_77.

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Suzuki, Hiroshi, Yoshitaka Hosokawa, Haruo Toda, Morimitsu Nishikimi, Akio Matsukage, Michihiro C. Yoshida, and Takayuki Ozawa. "Nuclear Genes Encoding Two Subunits of Human Mitochondrial Cytochrome bc1 Complex, Cytochrome c1 and Ubiquinone-Binding Protein: Their Structural Organization of the 5′-Flanking Regions and Chromosomal Localization." In Bioenergetics, 353–62. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4684-5835-0_33.

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Conference papers on the topic "C1 Complex"

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de Agostini, A., F. Barja, S. Carrel, P. C. Harpel, and M. Schapira. "C1 -INHIBITOR: STRUCTURE-ACTIVITY RELATIONSHIPS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642903.

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Cl-inhibitor [C1 -In] and other protease inhibitors of the serpin superfamily inactivate serine proteases by forming bimolecular enzyme-inhibitor complexes, a reaction that is associated with changes in the inhibitor conformation. To determine the significance of these changes, we have examined the influence of various treatments on the binding to C1-In of monoclonal antibody 4C3. This antibody was previously shown to bind to an epitope created during the reaction of C1-In with the Arg-specific protease plasma kallikrein [K]: the site for 4C3 was expressed on the K-C1-In complex, on C1-In cleaved at position Pi and released from K-C1-In [C1-In*], but not on unreacted C1-In. The binding of 4C3 to the various forms of C1-In was now measured by radioimmunoassay and Western blot. Following inactivation by C1-In of the Arg-specific enzymes factor XII active fragment [Xllf] or C1s, the binding site for 4C3 was detectable on XIIf-CI-In, C1s-C1-In and C1-In*. However, when K or Xllf were incubated with heat-inactivated C1-In, bo+h enzymes remained active, no complex was formed, and the site for 4C3 was not created. When C1-In was cleaved by neutrophil elastase [E] (a Met-orVal-specific protease that is not inhibited by C1 -In), the 1st cleavage product C1-In’ retained inhibitory activity (as shown by its ability to form a complex with Xllf) but did not bind 4C3. However, subsequent cleavage of C1-In’ by E at position P3 yielded C1-In’, a product which was inactive but bound 4C3. Thus, identical conformational changes of C1-In (as assessed by the emergence of the site for 4C3) are seen when Cl-In inactivates its target enzymes while being cleaved at Pi or when the inhibitor is catalytically inactivated by cleavage at P3. Therefore, these changes are necessary but not sufficient for observing enzyme inactivation.
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2

Hao Zhang and Jing Bai. "Nonlinear Finite Element Analysis of C0-C1-C2 Complex under Physiologic Loads." In 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference. IEEE, 2005. http://dx.doi.org/10.1109/iembs.2005.1615902.

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3

Dobran, Mauro, Erika Carrassi, Valentina Liverotti, Alessio Iacoangeli, Alessandro Di Rienzo, Bizzocchi Gianluca, Pasquale Dorato, and Maurizio Iacoangeli. "“Extreme” Indication of the Endoscopic Endonasal Approach for Complex C1–C2 Fractures." In 31st Annual Meeting North American Skull Base Society. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1743796.

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4

Niu, Wei, Wensheng Niu, and Juan Cheng. "Withdrawal: Applications of Derived Grey Model for Complex System Forecasting." In 2018 Modeling and Simulation Technologies Conference. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2018. http://dx.doi.org/10.2514/6.2018-3750.c1.

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5

Brown, Martha C., and Michael G. Jones. "Correction: Investigation of Liner Axial Displacement in a Complex Acoustic Environment." In 25th AIAA/CEAS Aeroacoustics Conference. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2019. http://dx.doi.org/10.2514/6.2019-2566.c1.

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6

Hasbestan, Jaber J., and Inanc Senocak. "Withdrawal: rebl-AMR : A Parallel Red-Black Tree Adaptive Mesh Refinement Software for Complex Geometry Flow Simulations." In 2018 Fluid Dynamics Conference. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2018. http://dx.doi.org/10.2514/6.2018-3556.c1.

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7

Holevo, A. A., and V. M. Misiuchenka. "ENVIRONMENTAL IMPACT DURING THE CONSTRUCTION OF THE PETRIKOV MINING AND PROCESSING COMPLEX." In SAKHAROV READINGS 2021: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2021. http://dx.doi.org/10.46646/sakh-2021-2-362-368.

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The analysis of the main impacts on the environment during the construction of a mining and processing complex in Petrikov was carried out. The analysis showed that the most significant impact was on atmospheric air and groundwater. The scattering calculation showed that the greatest influence was exerted by nitrogen (II) oxide, nitric acid, potassium chloride, carbon oxide, unsaturated hydrocarbons, saturated aliphatic hydrocarbons C1-C10. The volume of surface runoff and the volume of chloride removal from the industrial site in the event of an emergency were also calculated. As water protection measures, complete isolation of the surface of the sites was envisaged, as well as the installation of a canal-water conduit with further purification of the drain and its use in the technological scheme provided for the operation of the mining enterprise.
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Xie, Ziyi, and Franklin L. Duan. "Withdrawal: A Novel Design for Thin Film Smart Sensors on Complex Aero-Engine Surface for High Temperature Measurement." In AIAA Scitech 2021 Forum. Reston, Virginia: American Institute of Aeronautics and Astronautics, 2021. http://dx.doi.org/10.2514/6.2021-1506.c1.

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9

"Dynamic modelling of complex systems under deep uncertainty using an exploratory multi-method approach." In 22nd International Congress on Modelling and Simulation. Modelling and Simulation Society of Australia and New Zealand (MSSANZ), Inc., 2017. http://dx.doi.org/10.36334/modsim.2017.c1.moallemi.

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10

Veloso, D., M. Shapira, F. Kueppers, and R. W. Colman. "MONOCLONAL ANTIBODY 13G11 RECOGNIZES PREKALLIKREIN, KALLIKREIN AND COMPLEXES OF KALLIKREIN WITH,C1-INHIBITOR AND. α2-MACR0GL0BULIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642901.

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Abnormal prekallikrein (PK) levels in plasma can be due to decreased biosynthesis or increased activation either by surface-activated factor XIIa (e.g., in septicemia) or by other proteases (e.g., in pancreatites). To study the products of activation of PK in plasma, intact normal plasma and plasma exposed to either activating surfaces or factor XII fragment, was immunoblotted from SDS-gels. MAb 13G11 which recognizes purified PK, kallikrein (KAL) and the complexes of KAL with Cl-inhibitor (Cl-Inh) and α2macroglobulin (α2M) formed from purified proteins detected a doubLet (88- and 85-kDa) which comigrated with PK and KAL but was not visible in PK-deficient plasma. Transfer of either PK in normal plasma (25-125 ng) or KAL (50-300 ng) added to PK-deficient plasma was proportional to the amount of protein applied to the SDS-gels. Activation of plasma decreased the intensity of the PK bands with the formation of new bands with molecular weights similar to those of KAL-Cl-Inh and KAL-α2M. Identity was confirmed by MAb 4C3 (reacts with KAL-Cl-In, not with KAL) and a polyclonal antibody to α2M. Increase of incubation temperature from 24 to 37 increased KAL-Cl-Inh and decreased KAL-α2M. Addition of an excess of a2M before surface activation caused an increase of KAL-α2M complex and a decrease of KAL-Cl-Inh. Addition of an excess of Cl-Inh increased KAL-Cl-Inh and decreased KAL-α2M. In addition, activation of Cl-Inh-deficient plasma showed lower KAL-Cl-Inh and higher KAL-a2M than those when normal plasma was activated. When the deficient plasma was treated with CH3NH2 to inactivate α2M, an increase at KAL position was observed since no inhibitors were active. These studies indicate that 13G11 will be useful to detect changes in the distribution of PK, KAL, KAL-Cl-Inh and KAL-α2M associated with abnormal activation of PK and/or abnormal availability of inhibitors in disease.
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Reports on the topic "C1 Complex"

1

Nimz, G. J. Feasibility of Using 36 C1 to Depict Water Infiltration at the Pit 7 Complex, LLNL Site 300. Office of Scientific and Technical Information (OSTI), January 2002. http://dx.doi.org/10.2172/15013386.

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