Journal articles: 'C.p.m.p'

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Canard, JM. "C.P.R.E. et pathologie Biliaire." Acta Endoscopica 30, S5 (October 2000): 592–93. http://dx.doi.org/10.1007/bf03022898.

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Soumoy, Hubert. "Loi organique des C.P.A.S. et loi accueil : quels enjeux pour les C.P.A.S. ?" Pensée plurielle 25, no. 3 (2010): 37. http://dx.doi.org/10.3917/pp.025.0037.

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PARKER, GEOFFREY D., NIGEL R. JONES, and GRACE SCOTT. "Cervical Myelopathy in C.P.P.D. Deposition Disease." Australasian Radiology 34, no. 1 (February 1990): 82–85. http://dx.doi.org/10.1111/j.1440-1673.1990.tb02815.x.

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Robert, P. Y., J. P. Adenis, P. Tapie, and B. Melloni. "Eyelid Hyperlaxity and Obstructive Sleep Apnea (O.S.A.) Syndrome." European Journal of Ophthalmology 7, no. 3 (July 1997): 211–15. http://dx.doi.org/10.1177/112067219700700302.

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Purpose. An association between the floppy eyelid syndrome and the obstructive sleep apnea syndrome (O.S.A.) has been reported. We studied eyelid tissue elasticity and other ophthalmologic findings in a large number of patients with sleep disorders. Material and Methods. Sixty-nine patients with sleep disorders were evaluated. Two thirds were found to have O.S.A., and one third was treated at night by nasal continuous positive airway pressure (nasal C.P.A.P.). Slit lamp examination, eyelid measurements and Schirmer test were performed. Results. Eyelid hyperlaxity was increased in patients with O.S.A. The floppy eyelid syndrome (associated papillary conjunctivitis), however, was rare. Associated corneal lesions were rare, and most patients were asymptomatic. In some cases, ocular irritation was due to air leaks from nasal C.P.A.P. A significant proportion of patients required treatment for primary open angle glaucoma. Conclusions. Our study of 69 patients found an association between O.S.A. and eyelid hyperlaxity.

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Rey, J. F., P. Dellamonica, M. Greff, J. M. Bidart, and L. Mangialavori. "Infections et cholangio-pancreatographie rétrograde endoscopique (C.P.R.E.)." Acta Endoscopica 16, no. 1 (February 1986): 31–38. http://dx.doi.org/10.1007/bf02966222.

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&NA;. "C.P.M. Ankle Only Movement." Orthopaedic Nursing 7, no. 2 (March 1988): 64. http://dx.doi.org/10.1097/00006416-198803000-00011.

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Stefanescu, Dragos Cristian, Razvan Hainarosie, and Viorel Zainea. "Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea." Revista de Chimie 69, no. 6 (July 15, 2018): 1431–34. http://dx.doi.org/10.37358/rc.18.6.6340.

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Although it seems to be an exhausted subject at first glance, the therapeutic approach in obstructive sleep apnea syndrome (O.S.A.S.) is still an open subject. The continuous positive airway pressure (C.P.A.P.) represents the gold standard of therapy in O.S.A.S. However, this therapeutic process with C.P.A.P. has a low rate of compliancy, over 50% of patients quit in the first year of use. Implicitly, surgical solutions or mandibular advancement devices remain an alternative for many of these patients. High costs, complexity and risks associated with surgery have led to the identification of more accurate methods for topographic and functional diagnosis in O.S.A.S. Drug-induced sleep endoscopy (D.I.S.E.) with target-controlled infusion (T.C.I.) using propofol in the management of patients with obstructive sleep apnea is a relatively recently introduced method in Romania. The present paper describes our experience with D.I.S.E for selected patients, who have undergone surgery on the upper airway for O.S.A.S. The D.I.S.E method has led to the modification of the initial surgical plan in over 60% of patients with multi-level obstruction. Under these conditions, the surgical success rate in patients of the study increased to 80% at 6 months. Considering the specific endowment of each tertiary sleep center, the presence or absence of an operator block and the anesthetist�s experience with target-controlled (T.C.I.) infusion using propofol, more extensive and multicenter studies are needed for standardization of D.I.S.E.

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Darnell, Angela. "C.P.V.E. — A Case Study: The Implications for Pastoral Care." Pastoral Care in Education 6, no. 4 (December 1988): 20–23. http://dx.doi.org/10.1080/02643948809470638.

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Lumpkin, James R., and R. Keith Tudor. "The C.P.M. and Job Satisfaction." International Journal of Purchasing and Materials Management 27, no. 3 (June 1991): 32–37. http://dx.doi.org/10.1111/j.1745-493x.1991.tb00538.x.

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Hambleton, Ronald K. "Validity of the C.P.M. Examination Process." Journal of Purchasing and Materials Management 22, no. 2 (June 1986): 2–10. http://dx.doi.org/10.1111/j.1745-493x.1986.tb00156.x.

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Yépez-Yerovi, Fabian Eduardo, and Roberto Paúl Andrade-Salinas. "Post ERCP duodenal perforation of late diagnosis: A case report." Medwave 20, S1 (February 28, 2020): eCS03-eCS03. http://dx.doi.org/10.5867/medwave.2020.s1.cs03.

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Cannavò, S., F. Ferraù, M. Ragonese, L. Curtò, M. L. Torre, M. Magistri, A. Marchese, A. Alibrandi, and F. Trimarchi. "Increased prevalence of acromegaly in a highly polluted area." European Journal of Endocrinology 163, no. 4 (October 2010): 509–13. http://dx.doi.org/10.1530/eje-10-0465.

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ObjectiveDespite the contribution of national registries and population-based reports, data concerning the epidemiology of acromegaly is scanty. In addition, the role of the environmental context has not been investigated.DesignEpidemiology of acromegaly was studied in the province of Messina (Sicily, Italy), focusing on the influence of environmental factors.MethodsFour zones, characterized by different degrees of exposition to environmental toxins due to industrial pollution, were identified in the province: area A (76 338 inhabitants), area B (287 328 inhabitants), area C (243 381 inhabitants), and area D (47 554 inhabitants) at low, middle-low, middle, and high industrial density respectively. We identified all acromegalics who were born and resided in the province of Messina, among patients either referred to our endocrine unit or referred elsewhere but recorded in the archives of the provincial healthcare agency.ResultsIn the province of Messina, we found 64 patients (2 in area A, 24 in area B, 28 in area C, and 10 in area D). Macroadenomas were 60%, the male/female ratio was 1, and mean age at diagnosis (±s.e.m.) was 45.4±1.6 years. Overall, prevalence was 97 c.p.m. in the province (26 c.p.m. in area A, 84 c.p.m. in area B, 115 c.p.m. in area C, and 210 c.p.m. in area D). Risk ratio (RR), calculated in every area assuming area A as a reference, showed an increased risk of developing acromegaly in people residing in area D (RR=8.03; P<0.0014).ConclusionThis study confirms the prevalence of acromegaly reported recently. The increased risk of developing this disease in area D suggests that the pathogenetic role of environmental context needs to be better evaluated.

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Colin, J. Y., and P. Chrétienne. "C.P.M. Scheduling with Small Communication Delays and Task Duplication." Operations Research 39, no. 4 (August 1991): 680–84. http://dx.doi.org/10.1287/opre.39.4.680.

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Azad, N., N. LaPaglia, L. Kirsteins, S. Uddin, J. Steiner, D. W. Williams, A. M. Lawrence, and N. V. Emanuele. "Jurkat cell proliferative activity is increased by luteinizing hormone-releasing hormone." Journal of Endocrinology 153, no. 2 (May 1997): 241–49. http://dx.doi.org/10.1677/joe.0.1530241.

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Abstract Jurkat cells were used to study the immunomodulatory role of luteinizing hormone-releasing hormone (LHRH) in immune cells. The Jurkat cell, a human mature leukemic cell line, phenotypically resembles resting human T lymphocytes and has been widely used to study T cell physiology. The data from this study demonstrate that the Jurkat cell concentration of immunoreactive LHRH was 210 ± 36 pg/106 cells and that of proLHRH was 188 ± 27 pg/106 cells (means ± s.e.m.). The authenticity of this LHRH immunoreactivity is documented in two ways. First, both Jurkat LHRH and proLHRH immunoreactivity demonstrate dilutional parallelism with hypothalamic LHRH and proLHRH. Second, Jurkat lysates show LHRH bioactivity by releasing luteinizing hormone from rat anterior pituitary cells in culture. The presence of substantial amounts of LHRH in medium in which Jurkat cells were cultured for 72 h indicated that LHRH can be released from the cells. Using specific primers to exons 2 and 4 of the LHRH gene, we have found that Jurkat cells (like human T cells) express LHRH mRNA. The LHRH agonist, des-Gly10,d-Trp6-LHRH ethylamide, significantly increases the proliferative activity of Jurkat cells, as assessed by tritiated thymidine incorporation, from 15 980 ± 1491 c.p.m. in controls to 28 934 ± 3395, 30 457 ± 3861 (P=0·05 vs control) or 35 299 ± 5586 c.p.m. (P<0·01 vs control) with 10−11, 10−9 or 10−7 m agonist respectively. LHRH antagonist, [d-pGlu1,d-Phe2,d-Trp3,6]-LHRH, at a concentration of 10−8 m decreases Jurkat cell proliferative activity from 17 145 ± 526 c.p.m. in control medium to 10 653 ± 1323 c.p.m. (P=0·05). Co-incubation with the LHRH antagonist completely inhibits the proliferative stimulation induced by the LHRH agonist. Furthermore, applying monoclonal LHRH antibody to Jurkat cells inhibits the cell proliferative activity assessed by tritiated thymidine incorporation from 19 900 ± 2675 c.p.m. in controls to 15 680 ± 2254, 15 792 ± 1854 and 9700 ± 908 c.p.m. in media with 1:40, 1:20 and 1:10 dilution of purified antibody respectively (P<0·01, 1:10 dilution compared with control). In addition, the cAMP level in LHRH-stimulated Jurkat cells is decreased to 74, 27 and 57% of control levels after 15, 30 and 45 min respectively of exposure to 10−7 m LHRH agonist. In summary, Jurkat cells produce, process and release immunoreactive and bioactive LHRH, as do normal human T cells. Endogenous and exogenous LHRH increase Jurkat cell proliferative activity, and cAMP may be involved in LHRH-induced Jurkat cell proliferation. The Jurkat cell may be a useful model with which to study the role of LHRH in human T cell function. Journal of Endocrinology (1997) 153, 241–24

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Corallo, J., J. Boyer, J. M. Canard, J. Lapuelle, M. Greff, G. Schenowitz, J. F. Bretagne, et al. "Resultats de Ľenquete Française sur les conditions de la pratique de la C.P.R.E. en 1997." Acta Endoscopica 30, S5 (October 2000): 667–70. http://dx.doi.org/10.1007/bf03022932.

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Krishna, A., and P. F. Terranova. "Effect of the gonadotrophin surge at pro-oestrus on steroidogenesis and gonadotrophin binding of preantral follicles in the cyclic hamster." Journal of Endocrinology 114, no. 1 (July 1987): 49–54. http://dx.doi.org/10.1677/joe.0.1140049.

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ABSTRACT The present study describes the acute changes in steroids and human chorionic gonadotrophin (hCG) and FSH binding of preantral follicles induced by the gonadotrophin surges on the day of pro-oestrus. Preantral follicles were isolated by microdissection before (09.00–10.00 h), during (15.00–16.00 h) and after (21.00–22.00 h) the LH surge on pro-oestrus. Follicles at each time-period were pooled and steroid concentrations and gonadotrophin receptors determined. Before the LH surge, concentrations of progesterone and androstenedione were 40·8 ± 6·1 (s.e.m.) and 10·7 ± 3·9 fmol/follicle respectively. At the peak of the LH surge, progesterone and androstenedione concentrations in preantral follicles increased to 848 ± 186 and 129 ± 33 fmol/follicle respectively. Immediately after the LH surge, progesterone increased to 1238 ±97 fmol/follicle whereas androstenedione declined to 13·3 ±2·1 fmol/follicle. Oestradiol was less than 6 fmol/follicle throughout these periods. Binding of hCG and FSH to preantral follicles increased after the surge (hCG, 56± 2·6 c.p.m./follicle; FSH, 29·8 ± c.p.m./follicle) when compared with values obtained before the surge (hCG, 15·8± 4·0 c.p.m./follicle; FSH, 14·1 ± 1·9 c.p.m./follicle). Also, hCG binding increased significantly (P<0·05) from 09.00 to 21.00 h (56 ±2·6 c.p.m./follicle). In order to ascertain which follicular compartments were affected by the LH and FSH surges on pro-oestrus, granulosa cells and thecae from preantral follicles were isolated and steroid concentrations and LH and FSH binding measured. Both thecal and granulosal concentrations of androstenedione were significantly (P<0·01) higher at the peak of the LH surge (15.00 h) than at 09.00 h (before the surge) and 21.00 h (after the surge). The granulosal concentration of progesterone was lowest at 09.00 h, highest at 15.00 h and remained increased at 21.00 h. Thecal progesterone concentrations did not increase significantly until 21.00 h at pro-oestrus. Binding of hCG to theca increased significantly (P<0·01) at 15.00 and 21.00 h when compared with values at 09.00 h. Binding of FSH to theca was not detected at 09.00 h and was low at 15.00 and 21.00 h. Binding of hCG and FSH to granulosa cells did not change significantly throughout this period on pro-oestrus. These results indicate that the gonadotrophin surges on pro-oestrus induce significant stepwise increases in thecal LH binding in preantral follicles and that these coincide with parallel increases in follicular progesterone. Thus the gonadotrophin surges on pro-oestrus may be a signal regulating the onset of steroidogenesis and growth of preantral follicles. J. Endocr. (1987) 114, 49–54

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TANAKA, Kiyotaka, Yoichi TOYOMIZU, and Hiroaki KOBAYASHI. "A Study on the Maneuverability of the Ship with C.P.P." Journal of Japan Institute of Navigation 77 (1987): 175–83. http://dx.doi.org/10.9749/jin.77.175.

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Caraceni, Lina. "La vittima nel procedimento de libertate: i precari equilibri di un nuovo protagonismo ancora troppo poco meditato." Revista Brasileira de Direito Processual Penal 7, no. 3 (October 31, 2021): 1783. http://dx.doi.org/10.22197/rbdpp.v7i3.632.

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Una nuova sensibilità per le istanze di cui è portatrice la vittima del reato ha determinato un rafforzamento del suo ruolo nell’ambito del procedimento penale in una duplice dimensione: come destinataria di misure atte a proteggerla nel processo (vittimizzazione reiterata) e dal processo (vittimizzazione secondaria) e come soggetto attivo, capace di esercitare diritti e facoltà a tutela della propria integrità psico-fisica. E il sistema di protezione è stato costruito guardando prioritariamente alle vittime vulnerabili, nel perimetro delle indicazioni fornite dal diritto dell’Unione europea. I principali interventi di riforma hanno interessato la materia cautelare: sono state introdotte misure pro victima (gli artt. 282- bis e 282-ter c.p.p.) ed è stato riconosciuto alla persona offesa un diritto all’informazione sull’evoluzione dello status custodiae dell’accusato (artt. 90-ter, 282-quater e 299 comma 2-bis c.p.p.) a cui è associato un diritto di interlocuzione nel procedimento per la revoca e la sostituzione di una misura cautelare (artt. 299 commi 3 e 4-bis c.p.p.). L’analisi sarà condotta su questo secondo aspetto, evidenziando che si è trattato di scelte normative che assegnano alla vittima un nuovo protagonismo sulla scena processuale. Peccato che la traduzione normativa di tali intendimenti non abbia sortito gli effetti sperati: un lessico giuridico non sempre impeccabile, unito ad una scarsa sistematicità di novelle ripetute, non soltanto mettono in discussione l’obiettivo di protezione della vittima, ma rischiano anche di neutralizzare quel sistema di garanzie per l’accusato su cui si regge il procedimento cautelare.

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Barbu, Denisa. "Implications Generated by the Moment Established by the Law for Introducing the Civilly Responsible Party and the Moment Up Until the Injured Person Can Constitue as a Civil Party." Logos Universality Mentality Education Novelty: Law 8, no. 1 (December 10, 2020): 53–59. http://dx.doi.org/10.18662/lumenlaw/8.1/36.

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The civilly responsible party can be introduced, according to art 21, alin (1), C.p.p. as modified through CCR Decision up until the end of the criminal persecution by the person in right according to the civil law, in order to be able to formulate requests and to raise exceptions in the preliminary chamber. So, the civil party, as the person in right by the civil law, can ask to be introduced the civilly responsible party by the end of the criminal prosecution. On the other hand, the injured person can constitue as a civil party, as art. 20, alin (1) C.p.p. statues, up until the beginning of the judicial research. Therefore, in the situation that the civil party is not constituted up until the beginning of the preliminary chamber and she does not ask to be introduced the civilly responsible party is there an infringement of the right of the prosecuted? Nor the ones of the civilly responsible party? Are there any remedies?

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Capriello, Luigi. "Il regime di applicabilità dell’art. 578-bis c.p.p. in rapporto alla natura della confisca per equivalente." Fascicolo 1 | luglio-dicembre 2022, no. 1 (November 29, 2022): 1–28. http://dx.doi.org/10.35948/rdpi/2022.9.

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Le Sezioni unite della Corte di cassazione si sono recentemente pronunciate in ordine alla questione relativa alla individuazione dei limiti dell’efficacia retroattiva della disposizione ex art. 578-bis c.p.p. Il quesito oggetto di rimessione concerne l’applicabilità, o meno, di detta norma del codice di rito anche con riferimento alla confisca per equivalente disposta in relazione a un fatto di reato commesso anteriormente alla entrata in vigore dell’art. 1, comma 4, lett. f), legge 9 gennaio 2019, n. 3, che ha inserito nell'art. 578-bis c.p.p. le parole «o la confisca prevista dall’art. 322-ter cod. pen.». Alla base del contrasto che ha reso necessario l’interpello delle Sezioni unite vi sono le diverse interpretazioni offerte dalle pronunce delle Sezioni semplici in ordine al rapporto tra la natura “processuale” della disposizione di cui all'art. 578-bis c.p.p., come tale soggetta al principio tempus regit actum, e il carattere afflittivo della confisca per equivalente. La recente pronuncia fornisce lo spunto per condurre un’analisi dell’istituto su un piano generale, alla luce delle molteplici disposizioni che ne definiscono la disciplina normativa e delle numerose pronunce sul tema da parte della giurisprudenza di legittimità.   Parole chiave: Estinzione del reato per prescrizione, Confisca per equivalente, Principio di irretroattività   The relationship between the nature of the confiscation by equivalent and the applicability regime of Article 578-bis of the Code of Criminal Procedure: screening of the united Sections. The United Sections of the Court of Cassation have recently ruled on the question regarding the identification of the limits of the retroactive effective of the law provision under Article 578-bis of the Criminal Procedure Code. The question referred to the Court concerns the applicability, or not, of that law provision also with reference to the confiscation by equivalent ordered in relation to an act of crime committed prior to the entry into force of Article 1, paragraph 4, letter f), Law No. 3 of January 9, 2019, which inserted in Article 578-bis of the Code of Criminal Procedure the words “or the confiscation provided for in Article 322-ter of the Criminal Code” Underlying the contrast which made the intervention of the Joint Sections necessary are the different interpretations provided by some of the Simple Sections’ roulings regarding the relationship between the “procedural” nature of the law provision in Article 578-bis c.p.p., as such subject to the principle tempus regit actum, and the afflictive nature of confiscation for equivalent. The recent pronouncement provides the cue to conduct an analysis of the legal institution on a general level, in light of the multiple law provisions defining its legal framework and the numerous pronouncements on the subject by the jurisprudence of legitimacy.   Keywords: Extinction of the crime due to lapse of the statute of limitations, Confiscation by equivalent, Principle of non-retroactivity

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Bosscher, Ph M. "C.P.M. Slegers, Mensen uit de kringen van Brabants Heem. Heemkundebeoefening in Noord-Brabant." BMGN - Low Countries Historical Review 121, no. 2 (January 1, 2006): 307. http://dx.doi.org/10.18352/bmgn-lchr.6407.

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Broersma, M. "De hand van Romme. C.P.M. Romme als staatkundig hoofdredacteur van De Volkskrant (1945-1952)." BMGN - Low Countries Historical Review 115, no. 4 (January 1, 2000): 561. http://dx.doi.org/10.18352/bmgn-lchr.5342.

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Ullah, M. Usman. "Pak-China Partnership: U.S. And India's Response." Global Pakistan Studies Research Review IV, no. I (December 30, 2021): 40–46. http://dx.doi.org/10.31703/gpsrr.2021(iv-i).05.

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Pakistan and China have been enjoying multilayered ties. They have mutual cooperation and a supportive environment for each other. Their relationship has strengthened after the 2000s. They shifted their ties according to the global shadow. However, with the passage of time, their relationship transformed from Geo-economic to Geo-strategic. 2015 was the turning year of their ties with signing the C.P.E.C. project cost of $46Billion U.S. dollars. Both countries inked the agreement when the president of China, Xi Jinping, visited Pakistan in 2015. They are trying to safeguard their interests against the animosity of the U.S. and India. The pivot policy of the U.S. contains China's influence over the region. India is, on the other hand, sees it as a threat to its security.In this article, we are going to explore the ties between China and Pakistan and will observe the response of India and the U.S. towards them.

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Ullah, M. Usman. "Pak-China Partnership: U.S. And India's Response." Global Pakistan Studies Research Review IV, no. II (December 30, 2021): 40–46. http://dx.doi.org/10.31703/gpsrr.2021(iv-ii).05.

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Pakistan and China have been enjoying multilayered ties. They have mutual cooperation and a supportive environment for each other. Their relationship has strengthened after the 2000s. They shifted their ties according to the global shadow. However, with the passage of time, their relationship transformed from Geo-economic to Geo-strategic. 2015 was the turning year of their ties with signing the C.P.E.C. project cost of $46Billion U.S. dollars. Both countries inked the agreement when the president of China, Xi Jinping, visited Pakistan in 2015. They are trying to safeguard their interests against the animosity of the U.S. and India. The pivot policy of the U.S. contains China's influence over the region. India is, on the other hand, sees it as a threat to its security.In this article, we are going to explore the ties between China and Pakistan and will observe the response of India and the U.S. towards them.

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Seytmuratova, A. "4. Crimean Tatars: The Platform of the C.P.S.U. on Nationalities Policy and the Problems of the Crimean Tatar People Today." Nationalities Papers 17, no. 02 (1989): 244–47. http://dx.doi.org/10.1080/00905998908408122.

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Darmawidyawati, Darmawidyawati, Avit Suchitra, Emil Huriani, Susmiati Susmiati, Dally Rahman, and Elvi Oktarina. "Pengaruh Mobilisasi Dini Terhadap Penurunan Skala Nyeri Pada Pasien Post Operasi Laparatomi di Ruangan Intensive Care Unit." Jurnal Ilmiah Universitas Batanghari Jambi 22, no. 2 (July 26, 2022): 1112. http://dx.doi.org/10.33087/jiubj.v22i2.2300.

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Post Laparatomy pain can be minimized by giving pharmacological and non-pharmacological therapy. Nurses has a role to reduce the pain scale of patients with independent nursing care. One of them is early mobilization therapy. This study aims to determine the effect of early mobilization of decrease in pain scale in patients post operations laparatomy. True-experimental research design and use the pretest-posttest with a control group approach. The sampling technique uses Consecutive Sampling The number of samples was 30 people using the Slovin formula. Collection of pain scale data uses C.P.O.T and pain scale collected pre and post mobilization action, then analyzed univariate and bivariate with a Mann-Whiteney U . The results of the study were obtained by p-value <0.005 there was an effect of early mobilization of the reduction in pain scale. This research suggested that early mobilization actions can be used as one of the independent nursing interventions in dealing with pain problems in post laratomy patients at Intensive Care Unit

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Cassibba, Fabio Salvatore. "I limiti oggettivi del ne bis in idem in Italia tra fonti nazionali ed europee." Revista Brasileira de Direito Processual Penal 4, no. 3 (October 31, 2018): 953. http://dx.doi.org/10.22197/rbdpp.v4i3.186.

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É premissa consolidada que o ne bis in idem constitua um direito fundamental, protegido por uma pluralidade de fontes nacionais (art. 649 do c.p.p. italiano) e supranacionais (art. 50 CDFUE e 4° protocolo CEDH). Entretanto, exatamente a “tutela multinível” dos direitos fundamentais que caracteriza o ordenamento italiano – paradoxalmente – corre o risco de se transformar em um obstáculo à mais ampla operabilidade dessa garantia. Ademais, nos panoramas italiano e europeu, as previsões que especificam os pressupostos para a aplicabilidade dessa garantia se caracterizam por um conteúdo heterogêneo (identidade do fato; identidade da infração), destinado a incidir negativamente sobre a definição da perspectiva objetiva da proibição de dupla persecução. Por outro lado, a interpretação das mesmas previsões por parte da jurisprudência italiana, ordinária e constitucional, e pelas Cortes supranacionais torna ainda mais incertos os confins do efeito preclusivo gerado por uma decisão irrevogável. Em particular, alude-se as hipóteses em que o ne bis in idem entre em jogo em relação ao “duplo binário sancionatório”, por força do qual o mesmo fato é sancionado, contemporaneamente, em campo penal e em campo administrativo. A reconstrução da perspectiva da garantia atribuída ao art. 649 do c.p.p. italiano deve partir da valorização do princípio de legalidade processual e implica, portanto, por um lado, a recondução da unidade do pressuposto representado pelo mesmo objeto dos diferentes procedimentos; por outro lado, evitar soluções casuísticas, contrárias ao princípio de legalidade, em relação ao pressuposto da duplicação dos diferentes procedimentos que se refiram ao mesmo fato.

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Valentini, Elena. "Il “doppio binario cautelare”: la tormentata disciplina degli automatismi stabiliti dall’art. 275 comma 3 C.P.P." Revista Brasileira de Direito Processual Penal 7, no. 3 (October 31, 2021): 1669. http://dx.doi.org/10.22197/rbdpp.v7i3.631.

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Il contributo è dedicato all’analisi del cosiddetto “doppio binario cautelare”, e dunque della disciplina speciale, racchiusa nel secondo e terzo periodo dell’art. 275 comma 3 c.p.p. (oltre che nell’art. 12 comma 4-bis d. lgs. 25 luglio 1998, n. 286), che prevede alcune deviazioni dalla regolamentazione generale concernente le condizioni applicative e i criteri di scelta delle misure cautelari personali. Il saggio esordisce descrivendo la normativa prevista per i reati comuni, per poi concentrarsi sul regime derogatorio previsto per particolari categorie di delitti. A tale ultimo proposito, dopo aver descritto la travagliata evoluzione che ha contrassegnato la disciplina speciale dal 1991 ad oggi, l’A. si sofferma sulle criticità che tuttora connotano questo dispositivo di particolare rigore, nelle sue diverse declinazioni, anche alla luce della posizione espressa al riguardo dalla Corte costituzionale.

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Donovan, S. M., R. L. Hintz, and R. G. Rosenfeld. "Investigation into the potential physiological sources of rat milk IGF-I and IGF-binding proteins." Journal of Endocrinology 145, no. 3 (June 1995): 569–78. http://dx.doi.org/10.1677/joe.0.1450569.

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Abstract We have previously reported the presence of IGF-I and IGF-binding proteins (IGFBP-2, -3 and -4) in rat milk. Herein, the potential sources of rat milk IGF-I and IGFBPs were investigated. Lactating dams (day 14 postpartum) were separated from their pups and injected intraperitoneally with 0·45 μCi 125I-IGF-I or 125I-IGFBP-3. After 3 h, serum and milk of rats receiving 125I-IGF-I contained 7642 ± 3121 and 14 455 ± 7837 c.p.m./ml respectively. Serum and milk of rats given 125I-IGFBP-3 contained 7232 ± 1366 and 10 371 ± 4091 c.p.m./ml respectively. Sephacryl S-200 gel filtration chromatography demonstrated that the 125I-IGF-I in both serum and milk was primarily in the 150 kDa IGF-binding complex, whereas the distribution of 125I-IGFBP-3 differed between serum and milk. In serum, most of the 125I-IGFBP-3 was in the 150 kDa fraction, while most 125I-IGFBP-3 in milk was in the 40 kDa fraction. Northern analysis of liver showed IGFBP-1 and -3 mRNA expression, with variable expression of IGFBP-2 and -4 mRNA. In contrast, mammary tissue expressed only IGFBP-2 and -4 mRNA, suggesting that these IGFBPs in milk may arise from de novo synthesis within the mammary gland. The lack of detectable IGFBP-3 mRNA in mammary tissue and the translocation of 125I-IGFBP-3 from the serum suggest that milk IGFBP-3 arises from the maternal circulation. Journal of Endocrinology (1995) 145, 569–578

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Bex, Marie, Roger Abs, Guy T’Sjoen, Jean Mockel, Brigitte Velkeniers, Katja Muermans, and Dominique Maiter. "AcroBel – the Belgian registry on acromegaly: a survey of the ‘real-life’ outcome in 418 acromegalic subjects." European Journal of Endocrinology 157, no. 4 (October 2007): 399–409. http://dx.doi.org/10.1530/eje-07-0358.

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Objectives: To constitute a registry on acromegaly, AcroBel, to evaluate the epidemiology and quality of care of acromegaly in Belgium and Luxembourg. Design: A nationwide survey from June 2003 till September 2004 aiming to collect data from all patients with acromegaly who had visited the participating endocrine clinics after 1 January 2000. Methods: Retrospective data collection coupled to a visit within the survey period, allowing sampling of metabolic parameters and centralised determination of GH and IGF-I. Results: Four hundred and eighteen patients (51% men) were included, of which 96 were new cases, giving a mean incidence of 1.9 cases per million (c.p.m.) per year. The global prevalence was 41 c.p.m. but varied between 21 and 61 among different areas. Twenty-eight deaths were reported at a median age of 68 years in men and 74 years in women. The standardised mortality rate was significantly increased only in irradiated patients (2.70; confidence interval 1.60–4.55). Central measurements were available in 316 (75%) patients. Mean GH was ≤ 2 μg/l in 65% and IGF-I was normal for age in 56%, while both criteria were fulfilled in 49%. Multimodal treatment was more effective than primary medical therapy, since 56.5% were controlled versus 24.3% (P < 0.0001). Conclusions: AcroBel provides an excellent tool to analyse the prevalence, incidence, treatment modalities and outcome of acromegaly in Belgium. This real-life survey reveals that only half of acromegalic patients received an adequate therapy resulting in cure or disease control when stringent biochemical criteria are used.

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Ramadan, Baleanu, and Nassar. "Highly Accurate Numerical Technique for Population Models via Rational Chebyshev Collocation Method." Mathematics 7, no. 10 (October 1, 2019): 913. http://dx.doi.org/10.3390/math7100913.

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The present work introduces the application of rational Chebyshev collocation technique for approximating bio-mathematical problems of continuous population models for single and interacting species (C.P.M.). We study systematically the logistic growth model in a population, prey-predator model: Lotka-Volterra system (L.V.M.), the simple two-species Lotka-Volterra competition model (L.V.C.M.) and the prey-predator model with limit cycle periodic behavior (P.P.M.). For testing the accuracy, the numerical results for our method and others existing methods as well as the exact solution are compared. The obtained numerical results indicate the ability, the reliability and the accuracy of the present method.

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Martins, Erlon Leal. "A parte final do artigo 28 do C.P.P. e a independência funcional do Promotor de Justiça." Scientiam Juris 1, no. 1 (August 31, 2013): 18–24. http://dx.doi.org/10.6008/ess2318-3039.2013.001.0002.

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O tema tratado se refere na análise da possibilidade de o Procurador-Geral de Justiça designar um Promotor de Justiça, órgão de execução de 1º grau, para que ofereça, de forma obrigatória, a peça acusatória inicial, conforme a previsão contida na parte final do artigo 28 do Código de Processo Penal. A Constituição da República de 1988 elevou o Ministério Público a uma condição nunca vista, atribuindo novas funções, inclusive, a defesa da ordem jurídica e das instituições democráticas, e cercando-lhe de garantias para o bom desempenho de seu novo mister, elencando algumas destas à categoria de princípios, tais como a independência funcional, a unidade e a indivisibilidade, previstos no artigo 127, § 1º, da Carta Magna, que sequer podem ser suprimidos pelo Poder Constituinte Derivado, pois se assim fosse estar-se-ia a burlar as cláusulas pétreas. Por adquirir a natureza jurídica de princípio constitucional explícito, a independência funcional há de ser preservada e respeitada por todas as normas infraconstitucionais, para que não haja qualquer subordinação funcional em relação aos Procuradores e Promotores de Justiça, o que não se verifica na análise da parte final do artigo 28 do Código de Processo Penal, ao pronunciar que o Procurador-Geral de Justiça poderá designar um membro do Ministério Público para obrigatoriamente oferecer denúncia.

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La Rocca, Elvira Nadia. "L'art. 270 c.p.p. e la proporzionalità perduta : moniti per un recupero dalla Corte di giustizia UE." Archivio penale, no. 1 (2021): 131–54. http://dx.doi.org/10.12871/97888331809777.

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Bontempelli, Manfredi. "La resistenza del giudicato alla violazione del principio di legalità penale." Revista Brasileira de Direito Processual Penal 4, no. 3 (October 31, 2018): 1053. http://dx.doi.org/10.22197/rbdpp.v4i3.185.

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Deve-se submeter à atenta avaliação crítica a tese da jurisprudência e de uma parte da doutrina italiana segundo a qual a “coisa julgada” penal deveria “ceder” diante das violações dos direitos convencionais definidos pelo THDH, e das garantias constitucionais derivantes das intervenções da Corte Constitucional. O presente artigo analisa os espaços de conformidade do trânsito em julgado penal diante do juiz da execução segundo o “direito vivente”, e sobre seus relativos limites em razão da lei processual vivente. As mesmas exceções da força executiva da sentença irrevogável, previstas pelo c.p.p. taxativamente, confirmam a “intangibilidade” da “coisa julgada” e tornam implausível a hipótese de sua derrocada.

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Garcés Velásquez, Jaime. "Principios rectores del proceso penal acusatorio." Ratio Juris 1, no. 2 (September 1, 2017): 11–15. http://dx.doi.org/10.24142/raju.v1n2a1.

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De entrada, es importante resaltar dos aspectos fundamentales, a efectos de que me quedenentendibles estos supuestos que van a reglar el C.P.P. en el nuevo sistema acusatorio. Partamosde la base de que el nuevo sistema acusatorio deja intactos una serie de principios rectores que se consagran aún en todos los sistemas procesales anteriores, y que postulados como el de la DIGNIDAD HUMANA, LA COSA JUZGADA, EL JUEZ NATURAL, la DOBLE INSTANCIA, etc., que ustedes estudiaron en su cátedra de Procedimiento Pena, los conserva intactos el nuevo Código de Procedimiento Penal. De ahí, que haré énfasis en aquellos que han de ser objeto de caracterización esencial en el nuevo sisten1a acusatorio de la Legislación Procesal Penal en Colombia.

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Rodiere-Rein, C. "Les troubles dépressifs chez les schizophrènes vus en ambulatoire : Allure sémiologique et problèmes méthodologiques d’évaluation." Psychiatry and Psychobiology 1, no. 2 (1986): 131–38. http://dx.doi.org/10.1017/s0767399x00003217.

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RésuméLes symptômes d’un groupe de schizophrènes ambulatoires ont été évalués de manière transversale. 95 patients ont été inclus dans une première étude et 87 d’entre eux réévalués un an après.Les patients étaient considérés comme déprimés quand ils avaient : soit un score égal ou supérieur à 3 à une appréciation clinique globale de la dépression (de score maximum égal à 5), soit un score de 20 ou plus à la M.A.D.R.S.*.La fréquence de la dépression était de 20 % environ selon les deux modes d’évaluation.Les patients déprimés avaient aussi la symptomatologie psychiatrique d’ensemble la plus sévère comme en témoignaient leurs scores à la B.P.R.S.*, à l’échelle de schizophrénie extraite de la C.P.R.S.*, et à la check-list d’auto-évaluation S.C.L. 90*.Les deux modes d’évaluation de la dépression ont paru mesurer deux aspects différents du syndrome : dans la première étude, 20 patients étaient déprimés selon le score clinique global, 20 également selon la M.A.D.R.S., mais 12 seulement selon les deux modes d’évaluation. Comparée au score global, la M.A.D.R.S. paraît retenir des patients dont la pathologie globale et dépressive est plus sévère. Les cliniciens ont hésité à juger cliniquement comme déprimés des malades déficitaires même lorsque leurs profils cliniques avaient par ailleurs une configuration franchement dépressive.

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Salamonsen, L. A., R. J. Young, S. Garcia, and J. K. Findlay. "Mitogenic actions of endothelin and other growth factors in ovine endometrium." Journal of Endocrinology 152, no. 2 (February 1997): 283–90. http://dx.doi.org/10.1677/joe.0.1520283.

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Abstract Endothelin-1 (ET-1) is present in ovine endometrium, primarily in epithelial cells, and increases around the time of implantation. We examined the cell type expressing ET-binding sites in vitro and whether ET-1 has mitogenic actions in the endometrium, alone or in synergy with other growth factors. Purified epithelial and stromal cells were prepared from luteal-phase endometrium. Specific receptors were demonstrated by binding of 125I-ET-1 and proliferative effects of ET-1 and/or other growth factors determined by uptake of [3H]thymidine by cells in serum-free culture. 125I-ET-1 bound to both epithelial (2516 ± 820 c.p.m./well) and stromal (6368 ± 1350 c.p.m./well) cells and was displaced by ET-1 (1 μmol l−1). There were no proliferative effects of ET on epithelial cells. ET-1 (10 nmol l−1) stimulated uptake of [3H]thymidine by stromal cells under serum-free conditions in 13/20 individual cell preparations, to 149 ± 13% of control (untreated=100%) with dose-dependence between the range of 1 to 100 nmol l−1. Stimulation by fetal calf serum was to 377 ± 126% of control. The effects on proliferation by other growth factors (dose; % of control ± s.e.m., number of positives/total number of cell preparations) were: IGF-I (13 nmol l−1; 182 ± 14, 4/4), epidermal growth factor (EGF; 4·8 nmol l−1; 132 ± 5%, 7/7), platelet-derived growth factor-BB (0·4 nmol l−1; 146 ± 3, 2/2) and leukaemia inhibitory factor (0·4 nmol l−1; 110 ± 2, 3/3). All stimulations except that of EGF were significant and dose-responsive but only insulin was additive with ET (350 ± 35, 5/5). ET-1 also stimulated expression of the the AP-1 cis element c-jun, this being maximal at 60 min of exposure to mitogen. ET-1, along with other growth factors has a likely paracrine role in cellular proliferation in the endometrium, possibly in association with blastocyst implantation. Journal of Endocrinology (1997) 152, 283–290

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Ali, M. Arif, and Vijay Tukaram Salve. "Depression and COPD-association: not out of the blue." International Journal of Research in Medical Sciences 5, no. 9 (August 26, 2017): 3875. http://dx.doi.org/10.18203/2320-6012.ijrms20173698.

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Background: Depression is frequently associated with C.O.P.D. patients. Currently available treatment modalities are having limitations and chronic progression of the disease process in general causes decreased effort tolerance and poor socialization due to chronic cough and dyspnoea. Poor socialization and chronic symptoms result in mild depression to dysthymia and clinical depression. Three or more comorbidities associated with C.O.P.D. results in higher morbidity and mortality. Physician treating C.P.O.D. patients can use simple questionnaire based Hamilton depression scale to identify the patients having depressive symptoms.Methods: 50 diagnosed COPD patients as per GOLD guidelines were enrolled in the study after consideration of inclusion and exclusion criteria. Each patient was screened for depression using 17-point Hamilton depression scale. The results were tabulated and analyzed for statistical significance and compared with the data available on this topic.Results: Out of 50 stable COPD (diagnosed as per GOLD guidelines) patients enrolled for the study, 36 (72%) were males and 14 (28%) were females and in 19 (38%), (15 males and 4 females) patients HAM-D score was suggestive of depression. 10 (62.5%) patients from severe obstruction category (GOLD III) had mild depressive symptoms on HAM-D scale.Conclusions: Considering the fact that a significant number of COPD patients enrolled for the study had depressive symptoms, it is advisable to screen the patients for depression and psychiatrist consultations should be considered when required.

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Conti, Andrea. "L'ente a tutela dell'infanzia nel processo penale: l'alternativa tra costituzione di parte civile ed intervento ex artt. 91 ss. c.p.p." MINORIGIUSTIZIA, no. 3 (January 2019): 158–65. http://dx.doi.org/10.3280/mg2018-003017.

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De Souza, Marisangela Siqueira, Adriana Benevides Soares, and Clarissa Pinto Pizarro de Freitas. "Social Emotional Learning (sel) Program Among Fifth graders, Three and Six Months Later." Revista Colombiana de Psicología 31, no. 1 (January 1, 2022): 35–48. http://dx.doi.org/10.15446/rcp.v31n1.83042.

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This study carried out a follow-up three and six months after the application of a Social Emotional Learning (SEL) program, aiming to verify the maintenance of social skills in Elementary Education students in situations of social vulnerability from Rio de Janeiro, Brazil. A sample of the intervention and control groups composed of 20 students aged 10 to 13 (M = 10.3, SD = 0.8), boys and girls were selected. The SSRS (Social Skill Rating System) and the TDE (School Achievement Test) used in the intervention for teachers and students were reapplied. The results showed that the decrease in psychopathological symptoms and the improvements in academic performance were maintained after the intervention. These findings highlight the relevance of developing social emotional learning programs with elementary school students. How to cite this article: Souza, M.S., Soares, A.B., & Freitas, C.P.P. (2021). Social emotional learning (sel) program among fifth graders, three and six months later. Revista Colombiana de Psicologia, 31 (1), 35-48. https://doi.org/10.15446/rcp.v31n1.83042

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Flatt, Peter R., Adrian J. Bone, and Clifford J. Bailey. "Islet cell surface antibodies in genetically obese hyperglycaemic (ob/ob) mice." Bioscience Reports 5, no. 9 (September 1, 1985): 715–20. http://dx.doi.org/10.1007/bf01119868.

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A quantitative method for circulating islet cell surface antibodies (ICSA), based on the binding of125I-protein A to insulin-producing RINm5F cells, was used to evaluate ICSA in plasma of 4- to 40-week-old Aston obese hyperglycaemic (ob/ob) mice and normal control (+/+) mice. RINm5F cells bound 2502 ± l196 c.p.m.125I-protein A per 105 cells (mean ± S.D., n = 54) after incubation with +/+ plasma. ICSA positive plasma (defined as125I-protein A binding, mean ± 2 S.D. of +/+ plasma) was detected in 3 out of 54+/+ mice and 3 out of 54 ob/ob mice. ICSA were not observed in ob/ob mice before the onset of diabetes (7 weeks of age), but were detected at 9, 20 and 40 weeks. At 20 weeks125I-protein A binding produced by ob/ob plasma was 35% greater than +/+ plasma (P < 0.05). The low occurrence of ICSA in ob/ob mice (6%) suggests that factors other than ICSA are responsible for B-cell dysfunction and eventual islet degeneration observed in Aston ob/ob mice.

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Montalbán, Antonio. "Embedding jump upper semilattices into the Turing degrees." Journal of Symbolic Logic 68, no. 3 (September 2003): 989–1014. http://dx.doi.org/10.2178/jsl/1058448451.

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AbstractWe prove that every countable jump upper semilattice can be embedded in , where a jump upper semilattice (jusl) is an upper semilattice endowed with a strictly increasing and monotone unary operator that we call jump, and is the jusl of Turing degrees. As a corollary we get that the existential theory of 〈D, ≤T, ∨, ′〉 is decidable. We also prove that this result is not true about jusls with 0, by proving that not every quantifier free 1-type of jusl with 0 is realized in . On the other hand, we show that every quantifier free 1-type of jump partial ordering (jpo) with 0 is realized in . Moreover, we show that if every quantifier free type, p(x1,…, xn), of jpo with 0, which contains the formula x1 ≤ 0(m) & … & xn ≤ 0(m) for some m, is realized in , then every quantifier free type of jpo with 0 is realized in .We also study the question of whether every jusl with the c.p.p. and size is embeddable in . We show that for the answer is no, and that for κ = ℵ1 it is independent of ZFC. (It is true if MA(κ) holds.)

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Sánchez Gil, Iliana Andrea, and Javier Alberto Alcárcel Cepeda. "Estudio de constitucionalidad del parágrafo del articulo 57 de la ley 1453 de 2011." Revista Jurídica Mario Alario D´Filippo 9, no. 17 (January 1, 2017): 70–94. http://dx.doi.org/10.32997/2256-2796-vol.9-num.17/2017/209.

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La Ley 1453 de 2011, en el parágrafo del artículo 57, redujo el beneficio de descuento punitivo consagrado en el artículo 351 del C.P.P. cuando el imputado se allana a cargos, y fue declarado exequible por la Corte Constitucional a través de la sentencia C-645 del 24 de agosto de 2012. Este trabajo realiza un estudio de dicha normatividad a la luz de los principios de igualdad, legalidad, proporcionalidad, lealtad procesal, y además las garantías consagradas e integradas por vía del bloque de constitucionalidad, de lo cual se concluyó que no solo atenta dicha normatividad contra la estructura del sistema penal acusatorio y las garantías precitadas, sino contra los parámetros trazados por los diferentes instrumentos internacionales suscritos y aprobados por Colombia que se han integrado a nuestro ordenamiento interno, toda vez quedesconoce principios hermenéuticos que estructuran el favor rei como es el pro homine, pues ignora la interpretación más favorable en términos de sanción punitiva y de libertad del justiciable. Se deja en evidencia la falta de coherencia de la política criminal del Estado y el poco rigor jurídico en la decisión analizada de la Corte Constitucional.

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Salas Romero, Maria Dalila, and Maria Del Carmen Silva Cornejo. "CONOCIMIENTO DE LOS PADRES SOBRE SIGNOS DE ALARMA EN NIÑOS MENORES DE 5 AÑOS Y SU CONCURRENCIA INMEDIATA A UN SERVICIO DE SALUD TACNA-2007." Ciencia & Desarrollo, no. 11 (April 22, 2019): 75–78. http://dx.doi.org/10.33326/26176033.2007.11.229.

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Las Infecciones Respiratorias Agudas (IRA) y las Enfermedades Diarreicas Agudas (EDA) son las principales causas de muerte de menores de 5 años en los países en desarrollo. Los objetivos del presente trabajo fueron: Determinar la relación entre el conocimiento que tienen los padres sobre los signos de alarma en menores de 5 años y la concurrencia inmediata a un establecimiento de salud. El estudio es descriptivo - correlacional, de corte transversal en el Centro de Salud del C.P.M. Agusto B. Leguía de Tacna durante los meses de mayo a diciembre de 2007 y enero a marzo del 2008. La población estuvo determinada por las madres que llevaron a sus hijos al Centro. De las madres (n=56), el 82,1% (46) conocen por lo menos 2 signos de alarma de las Infecciones Respiratorias Agudas (IRAS), de las cuales 25 madres que conocen el riesgo llevan a sus vástagos al establecimiento de salud; comparado con el 60,7% (34) que conocen los signos de alarma sobre Enfermedad Diarreica Aguda (EDA) y solo 16 llevan al establecimiento de salud. No se encuentra relación significativa entre el conocimiento de los signos de alarma y la concurrencia al establecimiento de salud para ser atendidos.

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Angulo Salavarría, Marlon. "Análisis y revisión de la normativa que regula el funcionamiento de las sociedades de beneficencia." Ciencia Latina Revista Científica Multidisciplinar 6, no. 6 (December 27, 2022): 9912–31. http://dx.doi.org/10.37811/cl_rcm.v6i6.4108.

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El presente artículo, buscó realizar un análisis y revisión de la normativa que regula el funcionamiento de las Sociedades de Beneficencia (S.B), para ello ha sido necesario examinar la normativa que les dio origen, su evolución legislativa y otros aspectos relevantes que definen su situación actual. A fin de precisar si la naturaleza jurídico-legal de las S.B. se encuentra bien definida en la normativa vigente y saber si la promulgación del Decreto Legislativo N° 1411 y su modificación por Decreto de Urgencia 009-2020 estuvo acorde con las normas de rango superior, se analizaron distintas normas legislativas que establecieron su legalidad, basada en la fuente máxima del derecho peruano, la Constitución Política del Perú (C.P.P). Ello debido a que el planteamiento original postulaba su inconstitucionalidad; sin embargo, el análisis legal demuestra que su promulgación se encuentra en los límites que la propia carta magna faculta. Advirtiendo que no define claramente su naturaleza jurídica, vulnerando gravemente la situación legal de los trabajadores, al generar una situación laboral que establece un régimen disciplinario híbrido; a su vez, politiza y confiere mayor injerencia al gobierno central, sin promover la finalidad social para la que fueron creadas.

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Bharti, Aakanksha. "Hazard Exposure and Health Assessment of Construction Workers in New Delhi, India." International Journal of Preventive, Curative & Community Medicine 06, no. 02 (December 21, 2020): 22–27. http://dx.doi.org/10.24321/2454.325x.202009.

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Introduction: Construction workers are at a risk of a number of health-related problems, and are exposed to a plethora of occupational hazards. Due to dearth of studies on construction workers about various determinants playing key role on their health. Objectives: 1) To determine the socio-demographic status of construction workers. 2) To assess workplace hazard exposure among study subjects. 3) To evaluate the overall health of the study subjects. Method: An opportunity was created in a general health camp organised by Department of Community Medicine, VMMC and Safdarjung Hospital, Delhi in collaboration with Central Public Work Department (C.P.W.D) Officers’ Wives Association. All the construction workers attending the health camp were approached and only those who consented were included in the study. An interviewer administered questionnaire was filled for all the study subjects. Along with the questionnaire, detailed clinical examination was done, blood pressure and random blood sugar was measured. Simple tables and cross tables were made to present the data. Result: Total 129 construction workers were included in the study. Nearly 87% of the workers were employed on temporary or contract basis. 63.6% (n=82) spent 8 to 12 hours per day at work. Around half of the construction workers earned Rs. 10,000 per month or less. Thermal stress affected the maximum number of workers (54.3%), followed by dust (53.5%), followed by noise (38%). Around 10% (13) of the workers complained of having some health problem. Various complaints were generalised body ache, headache, weakness, fever, cough, cold, blood in sputum, decreased appetite and blood in stools. Conclusion: Construction workers are suffering from adverse health problems. There is the importance of regulating work hours of construction workers, periodic training on safe work culture and ways to reduce workplace injuries.

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Raeside, J. I., R. L. Renaud, R. M. Friendship, and M. W. Khalil. "Secretion of 19-hydroxyandrostenedione and 19-hydroxytestosterone by porcine Leydig cells in vitro and in vivo." Journal of Endocrinology 137, no. 2 (May 1993): 281–89. http://dx.doi.org/10.1677/joe.0.1370281.

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ABSTRACT 19-Hydroxytestosterone and 19-hydroxyandrostenedione have been identified as secretory products of the testes in the mature male domestic pig. Their isolation and identification were made by reverse-phase high-performance liquid chromatography and capillary gas chromatography-mass spectrometry (CGC-MS) of extracts from testicular vein blood and media of incubations with Leydig cells. Blood was collected from veins on the surface of the testes of anaesthetized boars. Collagenase-dispersed Percoll-purified cells (> 90% pure) were incubated (20 × 106 cells/flask) with androstenedione (8·75 μmol/l) or [3H]androstenedione (5 × 106 c.p.m.) for < 60 min. Steroids were recovered from plasma or media by solid-phase extraction and the unconjugated fractions chromatographed isocratically in two solvent systems (acetonitrile: water, 37:63 (v/v) and methanol: water, 70:30 (v/v)) before CGC-MS analysis. 19-Hydroxy-testosterone was present in greater quantities than 19-hydroxyandrostenedione in testicular vein blood; it was also seen as a quantitatively significant metabolite of unlabelled and radioactive androstenedione in the incubation studies. The demonstration of the secretion of 19-hydroxyandrogens from porcine testes thus raises questions concerning the physiological significance of a testicular, rather than an adrenal, secretion of these compounds. Journal of Endocrinology (1993) 137, 281–289

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Calliri Mamani, Henry Efrain, Gian Franco Chura Maquera, and Victor Miguel Carrillo Meléndez. "FRECUENCIA DE ENTEROBIUS VERMICULARIS EN NIÑOS ESCOLARES DEL NIVEL PRIMARIO DEL CPM "LOS PALOS"." Revista Médica Basadrina 1, no. 1 (May 14, 2019): 43–45. http://dx.doi.org/10.33326/26176068.2001.1.656.

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El nematodo Enterovirus vermicularis causa una parasitosis en el intestino y afecta con mayor frecuencia a niños y tiene carácter familiar. La forma infectante es el huevo larvado, que maduran luego de ser depositados en la periferia del ano. Esto se disemina por el rascado y son volátiles. Los síntomas en niños pueden ser: prurito anal, prurito vulvar: también alteraciones del comportamiento, reacciones alérgicas. Así un niño infectado amanece pálido y ojeroso, de aspecto apático o bien están inquietos. Este parásito es cosmopolita. El objetivo fue determinar la frecuencia de infección por Enterobius vermicularis en niños del único colegio del C.P.M. "Los Palos" de Tacna. Este poblado es zona agropecuaria, cercano a las playas de verano. Se tomaron 90 muestras de niños del nivel primario utilizando el método de la cinta celulosa (Método de Graham). Luego se buscó huevos por microscopio en dichas muestras. Se encontró 27.7% de niños parasitados por Eraerobius vermicularis siendo una frecuencia "regular" respecto a otros informes en Perú. Los niños de 6 a 9 años tuvieron mayores niveles de infección. Asimismo, se halló diferencias significativas en el sexo, en donde el 34.7% fueron positivas para el parásito en niños y solo 19.5% en niños. A pesar de que se acepte que el sexo no es factor determinante en esta parasitosis, podrían existir otros factores propios de cada población y región que influirían en estas diferencias.

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49

Clegg, R. A., D. W. West, and R. E. D. Aitchison. "Protein phosphorylation in rat mammary acini and in cytosol preparations in vitro Phosphorylation of acetyl-CoA carboxylase is unaffected by cyclic AMP." Biochemical Journal 241, no. 2 (January 15, 1987): 447–54. http://dx.doi.org/10.1042/bj2410447.

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Phosphorylation of soluble proteins in rat mammary acinar cells was investigated. When phosphorylation proceeded in intact cells, in the presence of [32P]Pi, the major non-casein phosphoproteins, including acetyl-CoA carboxylase, were unresponsive to incubation conditions that caused major increases in the intracellular concentration of cyclic AMP. The overall 32P specific radioactivity (c.p.m./microgram of protein) of acetyl-CoA carboxylase, assessed after affinity purification of the enzyme with avidin-Sepharose, was unchanged by incubation under such conditions. Furthermore, the distribution of 32P among tryptic phosphopeptides of the enzyme, resolved by reversed-phase h.p.l.c., was not altered by cyclic AMP-increasing treatments of the acinar cells. When cytosol fractions were incubated with [gamma-32P]ATP, some phosphoproteins responded to the addition of micromolar concentrations of dibutyryl cyclic AMP or cyclic AMP by undergoing an enhancement of phosphate incorporation. In these experiments in vitro, protein phosphatase activity did not make a major contribution to the net phosphorylation of individual phosphoproteins, and acetyl-CoA carboxylase was not prominent among the phosphoproteins identified after short (less than 1 min) incubations of cytosols with [gamma-32P]ATP. The resistance of protein phosphorylation to variations in the cyclic AMP concentration in intact mammary epithelial cells, demonstrated by this work, is one of several mechanisms that ensure the pleiotropic refractoriness of those cells to agents which normally cause a stimulation of adenylate cyclase activity in hormone-sensitive cells.

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Baricos, W. H., G. Murphy, Y. W. Zhou, H. H. Nguyen, and S. V. Shah. "Degradation of glomerular basement membrane by purified mammalian metalloproteinases." Biochemical Journal 254, no. 2 (September 1, 1988): 609–12. http://dx.doi.org/10.1042/bj2540609.

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Neutral metalloproteinases degrade components of the extracellular matrix, including collagen types I-V, fibronectin, laminin and proteoglycan. However, their ability to degrade intact glomerular basement membrane (GBM) has not previously been investigated. Incubation of [3H]GBM (50,000 c.p.m.; pH 7.5; 24 h at 37 degrees C) with purified gelatinase or stromelysin (2 units) resulted in significant GBM degradation: gelatinase, 46 +/- 2.2; stromelysin, 59 +/- 5.8 (means +/- S.E.M.; percentage release of non-sedimentable radioactivity; n = 4). In contrast, 2 units of collagenase released only 5.6 +/- 0.52% (n = 3) of the [3H]GBM radioactivity compared with 2.0 +/- 0.15% (n = 7) released from [3H]GBM incubated alone. Sephadex G-200 gel chromatography of supernatants obtained from incubations of [3H]GBM with either gelatinase or stromelysin confirmed the ability of these enzymes to degrade GBM and revealed both high-(800,000) and relatively low-(less than 20,000) Mr degradation products for both enzymes. GBM degradation by gelatinase and stromelysin was dose-dependent (range 0.02-2.0 units), near maximal between pH 6.0 and 8.6, and was completely inhibited (greater than 95%) by 2 mM-o-phenanthroline. Collagenase (2 units) did not enhance the degradation of GBM by either gelatinase (0.02 or 0.2 unit) or stromelysin (0.02 or 0.2 unit). Our results indicate that metalloproteinase-mediated GBM degradation by neutrophils and glomeruli may be attributable to gelatinase (neutrophils) and/or stromelysin (glomeruli) and suggest an important role for these proteinases in glomerular pathophysiology.

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Journal articles on the topic 'C.p.m.p'

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