Relevant bibliographies by topics / Bulbocapnine

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Academic literature on the topic 'Bulbocapnine'

Author: Grafiati
Published: 29 July 2024
Last updated: 30 July 2024

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Journal articles on the topic "Bulbocapnine"

1

Ribár, B., C. Mèszáros, O. Gašić, I. Kanyó, and P. Engel. "Structure of bulbocapnine." Acta Crystallographica Section C Crystal Structure Communications 47, no. 12 (December 15, 1991): 2612–14. http://dx.doi.org/10.1107/s0108270191006480.

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2

Parvin, Mst, Marcel Hrubša, Jaka Fadraersada, Alejandro Carazo, Jana Karlíčková, Lucie Cahlíková, Jakub Chlebek, Kateřina Macáková, and Přemysl Mladěnka. "Can Isoquinoline Alkaloids Affect Platelet Aggregation in Whole Human Blood?" Toxins 14, no. 7 (July 15, 2022): 491. http://dx.doi.org/10.3390/toxins14070491.

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Isoquinoline alkaloids have multiple biological activities, which might be associated with positive pharmacological effects as well as negative adverse reactions. As bleeding was suggested to be a side effect of the isoquinoline alkaloid berberine, we decided to ascertain if different isoquinoline alkaloids could influence hemocoagulation through the inhibition of either platelet aggregation or blood coagulation. Initially, a total of 14 compounds were screened for antiplatelet activity in whole human blood by impedance aggregometry. Eight of them demonstrated an antiplatelet effect against arachidonic acid-induced aggregation. Papaverine and bulbocapnine were the most potent compounds with biologically relevant IC50 values of 26.9 ± 12.2 μM and 30.7 ± 5.4 μM, respectively. Further testing with the same approach confirmed their antiplatelet effects by employing the most physiologically relevant inducer of platelet aggregation, collagen, and demonstrated that bulbocapnine acted at the level of thromboxane receptors. None of the alkaloids tested had an effect on blood coagulation measured by a mechanical coagulometer. In conclusion, the observed antiplatelet effects of isoquinoline alkaloids were found mostly at quite high concentrations, which means that their clinical impact is most likely low. Bulbocapnine was an exception. It proved to be a promising antiplatelet molecule, which may have biologically relevant effects.
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3

RIBAR, B., C. MESZAROS, O. GASIC, I. KANYO, and P. ENGEL. "ChemInform Abstract: Structure of Bulbocapnine." ChemInform 23, no. 14 (August 22, 2010): no. http://dx.doi.org/10.1002/chin.199214302.

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4

Zhang, Yong, Jung Shin, Sang Lee, So Kim, and Myung Lee. "Inhibition of Tyrosine Hydroxylase by Bulbocapnine." Planta Medica 63, no. 04 (August 1997): 362–63. http://dx.doi.org/10.1055/s-2006-957702.

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5

Shafiee, Abbas, Katayoun Morteza-Semnani, and Mohsen Amini. "(+)-Bulbocapnine-β-N-oxide fromGlaucium fimbrilligerum." Journal of Natural Products 61, no. 12 (December 1998): 1564–65. http://dx.doi.org/10.1021/np9801920.

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6

Slavík, Jiří, Ladislav Dolejš, and Leonora Slavíková. "Alkaloids from Corydalis solida (L.) SW. mass spectrometry of quaternary benzylisoquinoline alkaloids." Collection of Czechoslovak Chemical Communications 50, no. 10 (1985): 2299–309. http://dx.doi.org/10.1135/cccc19852299.

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From the strongly polar fraction from the tubers of Corydalis solida (L.) SW., a new quaternary alkaloid, (+)-N-methyllaudanidinium iodide, was isolated after conversion to iodides. Mass spectrometric behaviour of this type of quaternary alkaloids is described. In the tubers (0.37% of alkaloids) the main alkaloid component is (+)- and (±)-tetrahydropalmatine; other dominant alkaloids include protopine, (+)-corydaline, allocryptopine, dehydrocorydaline and jatrorrhizine. (±)-Corybulbine, (+)-corypalmine, (-)-isocorypalmine, (-)-scoulerine, (-)-stylopine, corysamine, palmatine, (+)-N-methyllaudanidinium hydroxide, (-)-cis-N-methylcanadinium hydroxide and cis-N-methylstylopinium hydroxide represent minor alkaloids. The last three mentioned were isolated in the form of iodides. Bulbocapnine, coptisine, berberine and columbamine were detected in trace amounts. The main alkaloid of the aerial parts of the plant (0.35% of alkaloids) is berberine, accompanied by coptisine, (-)- and (±)-canadine, (-)-stylopine, isoboldine, protopine, columbamine and (-)-cis-N-methylcanadinium hydroxide (isolated in the form of iodide) as significant components. Among minor alkaloids allocryptopine, (-)-isocorypalmine, (+)-corypalmine, (±)- and (-)-tetrahydropalmatine, corysamine, dehydrothalictricavine, palmatine and cis-N-methylstylopinium hydroxide (as iodide) were isolated and trace amounts of jatrorrhizine and bulbocapnine were detected.
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7

Kohli, Jai D., Dana Glock, and Leon I. Goldberg. "Bulbocapnine is not a selective DA1 receptor antagonist." Journal of Pharmacy and Pharmacology 38, no. 5 (May 1986): 401–2. http://dx.doi.org/10.1111/j.2042-7158.1986.tb04599.x.

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8

Sourkes, Theodore L. ""Rational hope" in the early treatment of Parkinson's disease." Canadian Journal of Physiology and Pharmacology 77, no. 6 (July 1, 1999): 375–82. http://dx.doi.org/10.1139/y99-049.

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The drug treatment of Parkinson's disease since the original description of the malady in 1817 is described. Consideration is given to the historic use of alkaloids of the belladonna, harmala, and aporphine families, and of amphetamine. The introduction of the L-dopa treatment is described. The modes of action of the various drugs employed in the past as well as those in current use are described in the context of knowledge of the functioning of the nigrostriatal tract.Key words: anticholinergic drugs, apomorphine, bulbocapnine, L-dopa, harmine.
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9

Shin, Jung Soo, Kyong Tai Kim, and Myung Koo Lee. "Inhibitory effects of bulbocapnine on dopamine biosynthesis in PC12 cells." Neuroscience Letters 244, no. 3 (March 1998): 161–64. http://dx.doi.org/10.1016/s0304-3940(98)00148-7.

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10

Kaya, G. Irem, Nehir Unver, Belkıs Gözler, and Jaume Bastida. "(−)-Capnoidine and (+)-bulbocapnine from an Amaryllidaceae species, Galanthus nivalis subsp. cilicicus." Biochemical Systematics and Ecology 32, no. 11 (November 2004): 1059–62. http://dx.doi.org/10.1016/j.bse.2004.03.006.

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Book chapters on the topic "Bulbocapnine"

1

"Bulbocapnine." In Natural Compounds, 339. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0560-3_594.

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