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1
Shah, Madad Ali. "Brunel DGPS system for blind navigation." Thesis, Brunel University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392073.
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Latif, Mohammad. "Innovation in university education : a case study of Brunel University." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.292836.
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Vencato, Massimo M. "Development and validation of the Brunel lifestyle physical activity questionnaire." Thesis, Brunel University, 2009. http://bura.brunel.ac.uk/handle/2438/4446.
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The purpose of the present programme was to develop and validate a theoretically-grounded instrument to measure the planned and unplanned dimensions of lifestyle PA (PPA and UPA; Dunn, Andersen, & Jakicic, 1998). In Study 1, two samples of British adults (Internet: N = 742; paper: N = 563) were used to establish the content validity of the Brunel Lifestyle Physical Activity Questionnaire (BLPAQ). Exploratory factor analysis yielded a two-factor model (UPA and PPA) that produced acceptable fit indices using confirmatory factors analyses with both samples. The purpose of Study 2 was to examine the test-retest reliability of the BLPAQ over 5 weeks using a sample of leisure centre users, university staff members, and university students (N = 337). High correlations were observed between the two administrations (range = .93-.98; p < .01). Thereafter, the data were subjected to proportion of agreement (PoA) analysis as advocated by Nevill, Lane, Kilgor, Bowes, and Whyte (2001). Both PPA and UPA demonstrated satisfactorily high internal agreement (PoA > 95%). In Study 3, the BLPAQ was cross-validated using two criterion measures: the Baecke Questionnaire of Habitual Physical Activity (Baecke, Burema, & Frijters, 1982) and the Godin’s Leisure-Time Exercise Questionnaire (Godin & Shephard, 1985). Multiple linear regressions were performed to predict PPA and UPA from the subscales of the two reference measures. The predictive models differed markedly in terms of gender. Subsequently, the sample of 338 British adults was divided into two subsamples, and these were subjected to a cross-validation using the Limits of Agreement (LoA) methodology advocated by Bland and Altman (1986). The agreement plots revealed that both BLPAQ subscales demonstrated acceptable inter-sample agreement when compared to the criterion measures. In Study 4, a series of structural equation models were tested with the aim of predicting PPA and UPA using the variables that constitute the Theory of Planned Behaviour (TPB). The TPB was able to predict PPA but not UPA. The addition of a direct path between past behaviour to UPA did not result in a significant prediction. Further work is required to examine the factorial structure of the PPA subscale and to increase the number of items in the UPA subscale. In sum, the programme has contributed a valid and reliable theory-based measure of PA as well as evidence to support the utility of the TPB in PA research. However, the TPB framework may require the addition of predictors such as past behaviour and actual behavioural control.
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Ahmad, Ariffin May Faezah. "The Role of Trade in the Economic Diversification of Brunel Darussalam." Thesis, University of Kent, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499713.
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Greenfield, David John. "I.K. Brunel and William Gravatt, 1826-1841 : their professional and personal relationship." Thesis, University of Portsmouth, 2011. https://researchportal.port.ac.uk/portal/en/theses/ik-brunel-and-william-gravatt-18261841-their-professional-and-personal-relationship(7b88ef95-7ee5-4d61-962c-d0bd379c9c68).html.
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The study concerns the personal and working relationship between Isambard Kingdom Brunel and William Gravatt during the design and construction of civil engineering projects in which they were jointly involved between 1826 and 1841. Brunel and Gravatt first worked together on the Thames Tunnel construction in 1826-1828 where, according to Brunel, they became 'intimate friends.' Subsequently Brunel employed Gravatt to assist him during the parliamentary process leading up to the passage of the second Great Western Railway Bill in August 1835. Gravatt then superintended, under Brunel, the design of bridges in the early stages of construction of the GWR. Having accepted the position of Engineer to the promoters of a railway from Bristol to Exeter in October 1835, Brunel selected Gravatt to manage the parliamentary survey for the line. Afterwards he engaged him as his Resident Engineer on the B&ER when construction of the line began in 1836. Meanwhile, the promoters of a scheme to improve navigation on the river Parrett engaged Brunel in late 1835 to appraise their proposals and to assist them in gaining their Act in 1836. On Brunel's recommendation, the newly incorporated Parrett Navigation Company engaged Gravatt as their Engineer. By 1839 Brunel and Gravatt were arguing vehemently over 'important engineering questions' affecting the B&ER. Their personal relationship deteriorated rapidly, culminating in Brunel dismissing Gravatt from the B&ER in June 1841. The study examines evidence of their working and personal relationship, with three objectives: firstly to establish their particular roles in the projects, secondly to establish the circumstances that led to the breakdown in their relationship, and thirdly to evaluate aspects of Brunel's leadership qualities based on the evidence of his professional and personal relationship with Gravatt.
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Tyson, Sarah F. "The assessment of posture and balance post-stroke." Thesis, Brunel University, 2002. http://bura.brunel.ac.uk/handle/2438/5546.
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Physiotherapy for people with stroke has been found to be beneficial but details of the most effective interventions are unclear. Further development of the evidence base for stroke physiotherapy is limited by a lack of clinical practice models, sensitive clinically based outcome measures and effective stratification techniques to characterise homogenous groups of subjects. These issues are addressed here with regard to balance and posture. These aspects were chosen because they form a cornerstone of stroke physiotherapy as they are thought essential for the rehabilitation of functional activities. A systematic review of assessment methods in the literature revealed a lack of measurement tools which met the utility criteria: reliability, validity, sensitivity to short-term change, suitability for a wide range of abilities, ease of use and suitability for different settings. This prompted the development of a new measurement tool. Firstly, a model of the clinical assessment process was developed using an adapted focus group method with neurological physiotherapists. This informed the content of a new measurement tool which combined an ordinal scale with functional performance tests- the Brunel Balance Assessment. The tool was evaluated in a series of studies involving 92 stroke patients. It was hierarchical (coefficient of reproducibility= 0.99, coefficient of scalability = 0.69), reliable (100% agreement) and valid as a measure of balance disability (r=0.58-0.97). The psychometric properties of the individual functional performance tests were also tested and found to be reliable (ICCs =0.88-1) and valid (r=0.32-0.63). Measurement error ranged 0-40% and the minimum change needed to detect true clinical change was calculated for each test. Balance disability, measured with the Brunel Balance Assessment, is heterogeneous with sitting, standing and stepping balance forming distinct levels of ability (p<0.027). Consequently, the BBA could be used to stratify people with stroke according to balance ability. Weakness, sensation and age were significant independent contributors to balance disability (r2=82.7%). Balance ability was a strong contributor to independence in ADL (p<0.0001). The findings of this thesis address the issues that have limited research into stroke physiotherapy with regard to balance disability. In relation to clinical practice, a robust measurement and stratification tool has been developed.
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Pilc, J. "Surfactants and enhanced oil recovery." Thesis, Brunel University, 1988. http://bura.brunel.ac.uk/handle/2438/5458.
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A large number of commercial and some novel Brunel synthesised surfactants have been studied with a view to their potential usefulness for enhanced oil recovery (EOR) application. Ethoxylated phenols and their sulphonated derivatives were given especially high priority. The surfactants were well-characterised in order to understand their EOR potential. High pressure liquid chromatography, mass spectrometry, Raman spectrometry, nuclear magnetic resonance spectrometry and other quantitative techniques were used. Aspects of their behaviour (as single components and as blends with co-surfactants and co-solvents) which have been considered in terms of: (i) phase behaviour with brine and hydrocarbons (ii) adsorption onto various oxide surfaces (iii) interfacial properties such as surface tension, wetting, contact angles and viscosity (iv) stability Three different blends using sulphonated surfactants which: (i) produce a microeinulsion which is stable to high salinity brines over a large temperature range (ii) exhibit low adsorption onto reservoir rock (iii) interfacial tension as low as 10-2mNm-1 have been subsequently optimised. Core flooding tests carried out under reservoir conditions produced an additional 20% of the original-oil-in-place.
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Brunel, Robert [Verfasser], Alfons [Akademischer Betreuer] [Gutachter] Kemper, and Torsten [Gutachter] Grust. "Enhancing Relational Database Systems for Managing Hierarchical Data / Robert Brunel ; Gutachter: Alfons Kemper, Torsten Grust ; Betreuer: Alfons Kemper." München : Universitätsbibliothek der TU München, 2017. http://d-nb.info/1147968195/34.
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Nicouleau-Brunel, Dominique. "Les examens morphologiques dans la pyélonéphrite aigüe de l'enfant : essai de corrélations à propos de 43 cas/ par Dominique Nicouleau épouse Brunel." Montpellier 1, 1996. http://www.theses.fr/1996MON11166.
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Moritz, Augustin [Verfasser], Klaus [Akademischer Betreuer] Obermayer, Klaus [Gutachter] Obermayer, Nicolas [Gutachter] Brunel, and Maurizio [Gutachter] Mattia. "Network dynamics of adaptive spiking neurons: model reduction and numerical analysis / Augustin Moritz ; Gutachter: Klaus Obermayer, Nicolas Brunel, Maurizio Mattia ; Betreuer: Klaus Obermayer." Berlin : Technische Universität Berlin, 2017. http://d-nb.info/1156187036/34.
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Wood, Philip Leslie. "The hydrodynamics of countercurrent chromatography in J-type centrifuges." Thesis, Brunel University, 2002. http://bura.brunel.ac.uk/handle/2438/5554.
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Countercurrent chromatography (CCC) is an advanced liquid-liquid extraction technique that purifies chemical components from complex mixtures. The Brunel CCC' is a J-type centrifuge based upon this technique. This machine can process 5g quantities of sample every 5 hours [Sutherland 1998]. To process 1 tonne of sample per year would require 200 Brunel CCCs, which is not practical as an industrial process. A practical alternative is to use one machine with 200 times the processing capability. To construct such a machine requires a greater understanding of the stationary phase retention inside a coil (column) and the column efficiency (mass transfer between the mobile and stationary phases). This thesis contains research into stationary phase retention. A hypothesis that all J-type centrifuges act as constant pressure drop pumps is proposed. This hypothesis combined with the Hagan-Poiseuille equation for laminar flow produces a theoretical basis for plotting the stationary phase retention against the square root of the mobile phase flow rate as proposed by Du et al [1999]. Supporting experimental evidence is presented showing that the mobile phase flows in a laminar manner and that the pressure drop across a coil is constant for a given set of operating conditions. It is shown that the pressure drop is the same in both normal and reverse phase modes if specific conditions are met. The pressure drop is shown to be independent of tubing bore for helical coils provided that the same helical pitch is used. The experimental results also show how the pressure drop varies with the phase system and rotational speed. Hopefully this is a significant advance in predicting the stationary phase retention of industrial scale J-type centrifuges.
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Gomes, Véronique. "Structure et propriétés interactives de l'antigène variable de Trypanosoma brucei brucel." Grenoble 2 : ANRT, 1988. http://catalogue.bnf.fr/ark:/12148/cb37613990k.
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Brunel-Geuder, Lisa [Verfasser], and Michael [Akademischer Betreuer] Lux. "Ist die Betreuung von Frauen mit einem familiären Mammakarzinomrisiko finanzierbar? Gesundheitsökonomische Betrachtung der genetischen Testung, intensivierten Früherkennung und präventiver Maßnahmen aus der Sicht des Gesundheitswesens und des Leistungserbringers / Lisa Brunel-Geuder. Gutachter: Michael Lux." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2015. http://d-nb.info/1076399118/34.
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Abarca, Cordero Julio César. "Jerome Seymour Bruner (1915-2016)." Pontificia Universidad Católica del Perú, 2017. http://repositorio.pucp.edu.pe/index/handle/123456789/102410.
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Haji, Wahsalfelah Siti Norkhalbi. "Traditional woven textiles : tradition and identity construction in the 'new state' of Brunei Darussalam." University of Western Australia. Anthropology and Sociology Discipline Group, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0013.
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Since its independence in 1984, politicians and nationalists in Brunei Darussalam have appealed to traditions in their efforts to create a national identity based on Brunei Darussalam’s national philosophy, `Malay Islamic Monarchy’. Weaving is one of the traditions related to Brunei traditional culture, thus traditional textile is used to construct national identity. This study focuses on the role played by powerful institutions in the creation of new tradition in order to foster national awareness in the `new state’ of Brunei Darussalam and I examine how traditional textiles are incorporated into the project of nation building. In Bruneian society, traditional woven cloths have multiple roles whose meanings vary according to the situation in which the traditional cloth is utilized. This research explores the significance of traditional textiles in Brunei Darussalam, focusing on the consumption of locally woven textiles in its traditions and the relationships to the expression and construction of identity. Since Islam came to Brunei Darussalam, it has become one of the predominant markers of identity of the Malays. This study analyse the influence of Islam in the production and consumption of traditional textile in Brunei Darussalam. The continuity of the production and consumption of traditional woven textile in Brunei Darussalam is very much dependent on its significant in the traditions of Brunei society as a whole. In order to prove this, this study focuses its investigation upon the production and uses of traditional textiles in the social customs of Malay society in Brunei Darussalam. Traditional woven textiles are employed to construct social identity in the reproduction of distinction. Traditional textiles are also offered to signify privilege and power. I examine how traditional textile is being used to distinguish social status and political prominence, denote offices, and display wealth and prestige.
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Mohammad, Harunthmarin Nur Qistin. "Culture, Tradition and the Series of Bruneian Folklore." Thesis, Griffith University, 2017. http://hdl.handle.net/10072/365267.
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This project is the first scholarly study on The Series of Bruneian Folklore and its significance as a legacy for the culture of Brunei. It is also the first English translation of selected tales in the Series. The broad trajectory of this thesis examines the survival of Brunei’s powerful oral narrative heritage which existed for 500 years as a vital part of traditional Bruneian society, and which still survives in the form of published children’s literature. Amidst modern culture, however, it is considered an outdated object of the past; this explains its deteriorating presence as a formative cultural force in the Brunei of today.
This dissertation transforms this perception of the Series and recognizes it as the embodiment of an important cultural and historical heritage. The main theoretical foundation is Homi Bhabha’s, The Location of Culture (1994) and the main literary framework is the Gothic mode: together they both serve as an overarching framework for analysis in each chapter. International literary perspectives are employed to achieve a cross-cultural examination of the Series, addressing this published expression of Brunei’s complex narrative heritage within the context of recent literary discourse. As a product of hybrid cultural influences and historical practices, published in a contemporary time frame, the Series has been approached with reference to Western literary concepts and modes of critique, including Postcolonialism, Feminism and the Gothic, addressing its importance as the reflection of a unique narrative heritage.Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Humanities, Languages and Social science
Arts, Education and Law
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Budde, Heike. "Antioxidant defense in Trypanosoma brucei brucei." [S.l.] : [s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=968912192.
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Jackman, Simon Andrew. "Dihydrolipoamide dehydrogenase in Trypanosoma brucei brucei." Thesis, University of Bath, 1991. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.760619.
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Razak, Abdul. "Brunei Bay northwest Borneo : depositional system." Thesis, University of Aberdeen, 2001. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=206630.
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Brunei Bay in Northwest Borneo is a semi circular marine embayment formed during the last marine transgression. It represent a complex tropical depositional system in a micro-mesotidal setting in which the following elements can be recognised - an elongate bird's foot delta with abandoned lobes, drowned river valleys, cuspate delta and classic tidal estuary - all within 50 krn of each other. Understanding the control on the morphology of the sand bodies produced within the overall depositional system is of great importance because it is believed that many of the subsurface hydrocarbon reservoirs in Northwest Borneo were deposited in a depositional setting similar to that of modern-day Brunei Bay. This study therefore has major implications for defining the architecture and connectivity of subsurface reservoirs. A detailed bathymetry survey of western Brunei Bay has been undertaken which acted as guide for subsequent hydrodynamic measurements and coring programme. The results of this study indicate that the localised depositional setting plays a key role in understanding sandbody geometry because the orientation of sandbodies and facies distribution varies considerably. Tidal processes playa significant role in shaping the sediment distribution and facies characteristic of the area although locally wave processes can play a significant role. Tidal sandbodies parallel to the direction of drowned rivers, form a large arcuate-shaped complex less constrained by the structural trend. This study suggests that within Brunei Bay, morphology and tidal range is not a good indicator of the dominant process. Mud, exceptionally rich in plant debris derived from the mangrove swamps, accumulates in low energy environments peripheral to the distributary channel, reinterpretation of many coal horizons in the Miocene of the region which have largely been ascribed to a raised setting. This study indicates that the present day Brunei Bay is an excellent analog for the tidally influenced succession of Northwest Borneo. Conversely, it also indicates that the Baram Delta located approximately 100 krn west of Brunei Bay is not a suitable analog for the interpreted wave influenced Miocene succession of Northwest Borneo.
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Gruer, Emmanuel. "Les tumeurs brunes osseuses de l'hyperparathyroïdie." Dijon, 1996. http://www.theses.fr/1996DIJOM026.
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"Les méthodes de diagnostic actuelles permettent dans la majorité des cas le diagnostic d'hyperparathyroïdie avant la survenue de complications graves, notamment rénales et osseuses, et parfois à un stade asymptomatique. Le principal examen complémentaire utilisé en cas de suspicion d'une hyperparathyroïdie est le dosage immunologique de la PTH intacte. Les techniques de localisation préparatoire ne sont le plus souvent pas indispensables, la cervicotomie exploratrice permettant à la fois le dépistage des lésions parathyroïdiennes et le traitement de la maladie de façon efficace. Certains auteurs préconisent dans ces cas particuliers un traitement médical conservateur. Les tumeurs brunes, dont nous rapportons une observation, sont une des manifestations osseuses pseudotumorales de l'hyperparathyroïdie. Avec la disparition des formes évoluées de cette maladie, ces tumeurs sont devenues plus rares. Il est cependant important de les inclure dans le diagnostic différentiel de lésions osseuses lytiques du squelette [. . . ]. " [Source : 4e de couv. ]
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Patočka, Radim. "Evropský justiční prostor - nařízení Brusel I." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-18167.
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The scope of this thesis is regulation (EC)No. 44/2001 on jurisdiction and the recognition and enforcement of judgements in civil and commercial matters. The provisions of Regulation is aiming the improvement and simplification of the recognition and enforcement of foreign judgements within the territory of the EU. According to the title of regulation this tesis is diveded in several parts explaining the key elements of developing the other maxime of the EU-free movement of judgements. First part includes the general fundamentals for determination of jurisdiction in cases with transborder element which is essential for aplication of this regulation as a part of legislation on international private law. Thanks to the nearly identical wording of Brussels I Regulation and Convention dealing with the same matter from the year 1968, all legal opinions of European Court of Justice related to that Convention can be invoked nowdays. Second part and third part turn to recognition and enforcement of foreign judgements in order to ensure the situation when "the declaration that a judgement is enforceable should be issued virtually automatically after purely formal checks of the documents supplied, without there being any possibility for the court to raise of its own motion on any of the ground for non-enforcement provided by this Regulation". The last part contents future trend in this sphere which can be seen from application of other regulation (European enforcement order, European order for payment procedure)giving rise to rapid and simple mechanism in specific cases. Especially it treats of cancellation special exequator proceeding which should be undertaken to achieve that foreign judgement would be enforceable.
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Tejralová, Pavlína. "Evropský justiční prostor: Nařízení Brusel I." Master's thesis, Vysoká škola ekonomická v Praze, 2011. http://www.nusl.cz/ntk/nusl-81851.
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The theme of my diploma thesis is one of the most important judicial acts of European private international law of civil procedure - Brussels I Regulation. The aim of my thesis was to analyse the Regulation from many views with an emphasis on the jurisprudence of European Court of Justice and of domestic national courts. First part of the thesis aims to describe the whole legal branch of european private international law of civil procedure and therefore place the Regulation in the context of the whole legal branch. second part of the thesis deals with the Regulation in its entirety and desribes every single article of the Regulation and tries to determine the boundaries of its application and interpretation. The last, third part, states othre relevant legal acts related to Regulation which are considered to be its alternative, and sums up the pros and cons of their application.
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Nannestad, Charles Leif. "The Role Of Students: Perceptions In Modifying Science And Mathematics Classroom Activities." Thesis, Curtin University, 2002. http://hdl.handle.net/20.500.11937/2077.
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The aim of this study was to provide teachers with a practical means to obtain timely indications of their students reactions to individual activities. Teachers could then modify their presentations of activities cognisant of those students perceptions. The study set out to establish a suitable instrument, and then to evaluate its use by classroom teachers.Five experienced science and mathematics teachers identified five characteristics of interest when considering students perceptions of classroom activities: Understand Content, Communication, Relevancy, Work Output, and Enjoyment. A fifteen-item instrument based upon these characteristics was developed for this study. The viability of the survey for use by busy classroom teachers was increased by the short and succinct format, as well as the provision of a computer graphing template to process and display responses. The combination of the survey and computer template is called the Students' Perceptions of an Activity Instrument and Display (SPAID).Teachers appreciated the provision of a structure to assist their reviewing the use of activities, and the rapidity with which the information was available. Students' responses provided timely support for teachers' decisions to engage classes in the activities and increased teachers' confidence in the worth of the activities. Alterations to activities were small in scale and idiosyncratic to the student cohorts. Teachers' use of the SPAID package was also noted to enhance cooperation with colleagues within the government secondary schools of Brunei Darussalam.
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Marie-Pierre, Hasne. "Amino acid transporters in Trypanosoma brucei brucei." Thesis, University of Glasgow, 2001. http://theses.gla.ac.uk/6544/.
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Two approaches have been used to investigate the nature of amino acid transport in T. brucei. The first approach involved studying the uptake of radiolabelled amino acids by the parasite, the second approach involved the identification, cloning and expression in a heterologous system of a gene encoding for a putative amino acid transporter. The biochemical approach revealed that methionine uptake was of relatively high affinity in procyclic and bloodstream forms and dependent on a proton motive force. The recognition motif of this transporter encompasses the amino acid core as well as the two carbon atoms of the side chain. The anionic amino acids, aspartate and glutamate, were shown to be taken up poorly or not at all by specific transport mechanisms in the two forms of the parasite. The aromatic amino acids, phenylalanine, tyrosine and tryptophan, are taken up via several different routes indicating the importance of these amino acids for the parasite. The cloning and expression of TbAATP1 in Xenopus oocytes revealed that this gene encodes for an amino acid transporter that is able to transport tyrosine, glutamine and glutamate. TbAATP1 is the first member of what was subsequently shown to be a family of genes, encompassing at least twelve members present on three different chromosomes (IV, VI, VIII). On chromosome IV six of these genes appeared to form a cluster.
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Pengiran, Haji Osman/Othman Pengiran Karim. "The evidence of oriental ceramic and earthenware distributions in Brunei Darussalam as an aid in understanding protohistoric Brunei." Thesis, University of Southampton, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242692.
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Haji, Mohd Daud Sabrina. "An examination of the challenges to implementing integrated land-use and transport (LUT) strategies to reduce transport emissions : a case study of Brunei-Muara and its sub-districts and their associated villages." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648324.
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Galland, Franck. "Planètes et naines brunes autour d'étoiles chaudes." Phd thesis, Université Joseph Fourier (Grenoble), 2006. http://tel.archives-ouvertes.fr/tel-00108982.
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Dans le cadre de la recherche de planètes extrasolaires et de naines brunes, cette thèse innove en se focalisant sur le cas d'étoiles naines de type spectral A et F, plus chaudes que le Soleil. J'ai développé une nouvelle méthode de mesure de vitesses radiales, que j'ai testée puis appliquée lors de recherches systématiques avec les spectrographes ELODIE et HARPS, qui a abouti pour le moment à la découverte de deux planètes et d'une naine brune, et de nombreux candidats. J'ai aussi développé des diagnostics de la présence de pulsations ou d'activité affectant la surface stellaire et les vitesses radiales mesurées. J'ai aussi conduit cette recherche en imagerie directe à haute résolution angulaire, en utilisant les instruments PUEO et NACO. Les compagnons candidats détectés doivent être confirmés. Cette recherche permettra d'établir les caractéristiques des planètes et naines brunes autour d'étoiles A et F, et l'influence de la masse de l'étoile-hôte sur les processus de formation.
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Salleh, Norzamni. "Sharing spatial data in Brunei government departments." Thesis, University of Salford, 2010. http://usir.salford.ac.uk/26890/.
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Spatial data are items of information related to a location on earth. The early forms of spatial data included maps, survey plans, coastal charts and geodetic triangulation. With the advancement of technology, this spatial data have increased its importance. Decision makers from many disciplines tend to rely on up-to-date relevant, wider and accessible spatial data as an essential input in supporting their operational and strategic decisions. The demand to access multi-organisations spatial data continue to increase and this has pushed organisation to share their spatial data as rarely all these data sets reside within one organisation. However, there are persistent challenges that limit the utilization of available spatial data across organizations. The existence of these challenges is a global phenomenon and Brunei, a small country in south East Asia is no exception. The main purpose of this research is to identify factors that impede spatial data sharing within government departments in Brunei and use the findings to develop a framework for sharing spatial data within the government departments. The proposed framework took the innovative approach of combining both technical and non- technical factors, which have not been currently addressed. This research adopted multiple holistic case studies in 3 selected government departments in Brunei. A comprehensive literature review of relevant topics helped in designing a preliminary guideline for research in spatial data sharing. This guideline is used as a basis for data collection and at the same time refined by the case studies. Both content analysis and cognitive mapping techniques were applied to help in customizing the framework for sharing spatial data in Brunei, the ultimate product of this research. The framework comprises of two different components, which include the contextual component and the collaborative process component. Under the collaborative process component, there were 5 key elements that are crucial in spatial data sharing. This includes leadership, formal agreement, IT structure, monitoring and review and security. The framework was not empirically validated due to the immaturity of spatial data sharing in Brunei, unable the framework to be validated empirically. At such, opinions from the experts on the appropriateness of the framework were elicited as an initial validation. Efforts were also made by assessing the impact of each key element to the past data sharing projects in Brunei. The research concluded that the proposed framework offers a viable and effective formal mechanism for data sharing and coordination of spatial activities within government departments in Brunei. It is envisaged that with minor amendments to the policy aspects, the framework is expandable for application to private sectors.
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Pg, Haji Hassan Dk Noor Hasharina Binti. "Everyday finances and consumption in Brunei Darussalam." Thesis, University of Southampton, 2010. https://eprints.soton.ac.uk/192863/.
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After the financial global crisis in 2008, there has been a growing interest in studying financialisation in economic geography mainly in Anglo-American societies. Most attempts in understanding finance in Geography focus on macro level finance culture i.e. examining financial structures and institutions. With financial iberalisation, financial institutions play a significant role in influencing the financial markets in Anglo-America while government interference has been declining. Social scientists such as Langley (2008) and Lee et al. (2009) identified a dearth of literature in economic geography that focuses on everyday personal finances of consumers and relate consumers’ borrowing culture to their consumption patterns which are shaped by social intermediaries including governments, family and traditions. This thesis fills this gap in contemporary areas in economic geography. The aim of the thesis is to examine the development of personal finances and consumption in Brunei Darussalam. Brunei makes a relevant case study due to its distinctive evolving personal finance and consumption culture where the government plays a significant role through the monitoring and regulating of financial institutions. Regulating Brunei’s financial structure was a pro-active action taken by the government to address problems of Bruneians’ dependency on borrowing to consume rather than as a reaction to the global financial crisis. Moreover, this study shows how individual choices and actions as well as traditional cultural intermediaries (du Gay et al., 1997) particularly the family and traditions shape Bruneians’ financial access and consumption culture. My thesis demonstrates that financialisation and consumption culture are not homogenised across different geographies, thus stresses the importance of acknowledging and need to consider social and cultural practices of consumers and governments in order to understand the financial and consumption culture and development of different societies.By employing mixed methods in particular qualitative research methods, this thesis also presents empirical evidence of the transformation in financial culture and identifies functions and motivators of consumption that affect consumers’ everyday finances in Brunei which are different from other geographies including Anglo- America
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Haji, Zaine Norafizah. "Establishment of the Brunei Diabetic Foot Registry." Thesis, The University of Sydney, 2015. http://hdl.handle.net/2123/13761.
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The overall aim of this thesis was to characterise the clinical features of diabetic and non-diabetic foot ulcers in one of the largest tertiary public hospitals in Australia and establish the first Diabetic Foot Registry in Brunei Darussalam to explore incidence, risk factors and optimal treatment pathways for the local community. For the first study, a total of 195 outpatients with diabetic foot ulcers were extracted from the Westmead Hospital’s Foot Wound Clinic Registry. It was concluded that diabetic foot ulcers are more likely to present on the plantar surface of the foot with a duration of 1 week to 3 months and largely affect older, overweight males with a long standing history of diabetes. Our findings were in accordance with the EURODIALE benchmark study in Europe. In contrast to patients with diabetic foot ulcers, our results for 202 outpatients with non-diabetic foot ulcers largely affect, on average, elderly males and females with normal BMI, on the plantar and dorsal aspect of the foot with a duration of 1 week to 3 months. In comparison with diabetic foot ulcers, socioeconomic status was also not related. The final studies were conducted to validate the Brunei Diabetic Foot Registry. The validation process involved test-retest of all Registry items in 26 patients by four podiatrists in the Podiatry Unit in Brunei, and a prospective 6 month pilot study of 56 patients to assess content validity of 63 items. All continuous data items exhibited “excellent” reliability (ICC1,1>0.94) and 67% revealed “almost perfect” agreement of nominal data items. Pilot data demonstrated that the Registry items comprehensively covered the presence, severity and characteristics of the diabetic foot ulcer cohort. In conclusion, the findings of this thesis have implications for clinical and health policy decisions and emphasise the importance of accurate patient registries in determining incidence, characteristics and treatment pathways of patients with diabetic foot ulcers.
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Kassim, Mona Yati Mohd. "Tourism in Brunei Darussalam : content and context." Thesis, Loughborough University, 2003. https://dspace.lboro.ac.uk/2134/34408.
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The purpose of this research was to analyse the content and context of tourism stakeholder management in Negara Brunei Darussalam and to investigate stakeholder views on tourism management, planning and development. The author attempted to identify the web of stakeholders as perceived by the main key groups of players in the tourism industry in the months leading up to the sultanate's first ever 'Visit Brunei Year 2001'. In addition, she attempted to investigate the underlying causes of ineffective tourism management in Negara Brunei Darussalam, which operates under a strict Malay Muslim Monarchy ('Melayu Islam Beraja' or'MIB') system of governance and national philosophy. Many hold the view that developing the tourism industry in Negara Brunei Darussalam is a necessary stepping-stone towards diversification from its dependence on oil and gas. However, very little effort has been made to educate the general community on its benefits and disadvantages. In addition, only a very select group of people are directly involved in its planning and development leading to conflict in the community. Little has been said about real community support of tourism development and on the impact it may have on its stakeholders. The present study has attempted to do this. Problems in tourism management, planning and development are expected to arise because of Negara Brunei Darussalam's inexperience in this field, lack of coordination and planning between government and private sectors; and, perhaps due to conflict between its MIB philosophy and the perceived negative nature of the tourism industry. Research was conducted in several stages from November 1999 to February 2001. Data collection from the fieldwork was elicited through questionnaires administered by four trained interviewers in all four districts in Negara Brunei Darussalam and through in-depth interviews with selected tourism stakeholders by the author. The author observed that key players of tourism were relatively unaware of the concept of community participation in tourism development and planning, as well as the identity of a wider range of tourism stakeholders. The community at large does support tourism development and planning and expectations for accrual of tourism revenue and benefits are high. Many in the private sector have voiced the view that the government should do more to give this industry a boost. Similarly, the governmental body believes that a pro-active private sector is needed for sustainability of this industry. An alternative model to western stakeholder management is proposed that is applicable to this small Muslim sultanate.
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Lionneton, Eric. "Elaboration d'une carte génétique de la moutarde brune (Brassica juncea L. ) et marquage moléculaire de caractères liés à la qualité de la graine." Dijon, 2002. http://www.theses.fr/2002DIJOS023.
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Brutel-Vuilmet, Claire Guyader Jean-Louis. "Prise en compte de l'angle d'incidence dans la caractérisation en laboratoire de la transmission acoustique des éléments de façade." Villeurbanne : Doc'INSA, 2006. http://docinsa.insa-lyon.fr/these/pont.php?id=brutel-vuilmet.
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Mohamad, Hanapi. "Promoting creativity in early childhood education in Brunei." University of Western Australia. Graduate School of Education, 2006. http://theses.library.uwa.edu.au/adt-WU2006.0130.
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[Truncated abstract] The overall aim of this study was to examine Bruneian preschool teachers’ conceptions about creativity (including factors related to creativity), their beliefs on how to promote children’s creativity in the classroom, how their beliefs may influence their actual practice and whether their practices are consistent with the requirements of the Brunei National Curriculum. It will also try to identify any factors that constrain or influence teachers’ practice. The research employed a grounded theory approach involving semi-structured interviews and classroom observations of preschool teachers. The findings of this study indicate that the teachers primarily conceptualise creativity as something mainly but not exclusively to do with art work . . . Teachers’ actual practice mainly consists of teacher control, enforcement of obedience, rote learning, teacher directed and teacher chosen activities and heavy emphasis on whole-class teaching. Other mediating constraints on their promotion of creativity included: pressure from Primary 1 teachers, parents and the officials in Ministry of Educations to complete and adhere to the National Curriculum; teachers’ own pedagogical limitations; large class size; lack of adult help and the presence of special children in the classroom; lack of resources and pressure from other non-teaching commitments. The implication of the findings are that further research needs to be conducted into Brunei’s preschool teacher training programmes, to identify contradictory messages about the value of creativity and to find a more culturally appropriate way of promoting children’s creativity through the curriculum.
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Herrboldt, Amy A. Dolskaya-Ackerly Olga. "Humanistic influences on the career of Antoine Brumel." Diss., UMK access, 2006.
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Thesis (M.M.)--Conservatory of Music. University of Missouri--Kansas City, 2006."A thesis in music history and literature." Typescript. Advisor: Olga Dolskaya-Ackerly. Vita. Title from "catalog record" of the print edition Description based on contents viewed Oct. 31, 2007. Includes bibliographical references (leaves 74-81). Online version of the print edition.
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Levy, Ruth. "Community structure of ants in Brunei rain forest." Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240586.
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Haji, Md Sum Hisham. "Educational dependency : a case study on Brunei Darussalam." Thesis, University of Reading, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335887.
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Haji, Awang Radzuan Mohammad Sofian. "Evolving Brunei Darussalam's economy towards technology-based industries." Thesis, University of Sussex, 2016. http://sro.sussex.ac.uk/id/eprint/65634/.
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Technology-Based Industries continue to be at the forefront of a nation's sustainable economic development. These account for the largest share of employment, business activity and labour income in most primary sectors. Technology-Based Industries contribute to multi-lateral development of a nation's economy through innovation, new technologies and use of new knowledge. The government of Brunei Darussalam sought in the past decade to diversify the economy with limited success. Oil and gas and government spending still account for most of Brunei's economic activity. The small size of the domestic market discourages foreign direct investment in Brunei Darussalam. Brunei's government encourages foreign investment especially when it involves emerging new technologies and technology transfers. The research question is: how to transfer new technologies into Brunei Darussalam industry and to quantify the impact of these Technology-Based Industries; can a resource based-economy offer a solution to tackle the difficulties in industrial advancement that Brunei Darussalam is currently struggling with. This research aims to study factors for the successful transfer of technology-based industries and identify the key issues in technology transfers that significantly affect the rate of technological integration and evaluate the concept of technology transfers and its contribution to the sustainable economic development of a small state economy. It adopts multiple techniques both inductive and deductive approaches through SWOT-analysis and case studies to explore and later analyze the importance of the visionary drive underlying the technology-based industrial strategy that contributes to policy improvement, via awareness of alternatives and discovery of latent policy constraints and opportunities from investigation of others' experience. The bottom line of this research is to provide the basis for government policies on how the technology transfer can be achieved in the Brunei Darussalam industrial context.
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Zhao, Lee Zhuo. "Brunet-Derrida particle systems and selectively accessible paths." Thesis, University of Cambridge, 2014. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708315.
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Ebil, Syazana. "Assessment of demersal fishery resources in Brunei Darussalam." Thesis, University of Warwick, 2013. http://wrap.warwick.ac.uk/57704/.
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A problem commonly encountered in stock assessments of tropical marine resources in developing countries is data paucity, which invariably results from the lack of both human and economic capacity within the government to implement and maintain programmes for data collection and analysis. With special reference to the demersal fishery of Brunei Darussalam, this thesis examines approaches for extracting useful information from data-poor fisheries to assess the state of resources and inform fishery management actions. By using official fishery statistics, augmented by local ecological knowledge (LEK) obtained from fishers engaged in either the large-scale (LS) or small-scale (SS) fisheries in Brunei, changes in demersal fishery resources over the years were assessed. The sustainability of Brunei’s demersal capture fishery was evaluated in the face of its ongoing development and climate change. Using trophodynamic indicators such as mean trophic level (MTL), Fishing-in- Balance (FiB), trophic spectra (TS) and community structure analyses, LS fishery catches of Brunei between 2000 and 2009 revealed a deteriorating state of the coastal demersal ecosystem. Closer examination of the abundance of overall demersal finfish stocks, using the Catch-Per-Unit-Effort (CPUE) index – standardised for other factors not related to abundance – indicated a declining trend, even when total catches remained stationary, although trends in abundance of the different demersal fish families varied. This rapid significant change in recent years is further supported by fishers’ LEK on relative abundance of Brunei marine resources. The study on LEK has also revealed the ‘shifting baseline syndrome’ (SBS) among currently active fishers and their exploited populations, a phenomenon not previously reported for Brunei fisheries. Findings from the study are synthesised with other information, where a number of key issues and policy options are discussed, and recommendations for the management of the fishery are made. This thesis demonstrates that researchers in data-poor fisheries can utilise different assessment tools, given the resources at their disposal, to assist in the management of marine resources.
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Sabtu, K. "Evaluation of diabetic retinopathy screening in Brunei Darussalam." Thesis, London School of Hygiene and Tropical Medicine (University of London), 2015. http://researchonline.lshtm.ac.uk/2391561/.
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In recognition of the increasing prevalence of diabetes in Brunei, and the expected increase in diabetic retinopathy (DR), primary health centre based DR screening was introduced in 2006 for seven health centres in the Brunei-Muara district. The Brunei National Prevention of Blindness from Diabetic Retinopathy is a policy document calling for DR screening to be made systematic at a national level. However, the effectiveness of the model in practice was not evaluated and the DR screening programme was launched without a baseline survey and situation assessment. Consequently, the responsiveness of the health system to embed a systematic approach to DR screening has faced many constraints and was slow to evolve. This study has provided evidence to support the implementation of the policy document and baseline information on the gaps and challenges within the key service provision stages for DR screening and treatment. The overall objective of this thesis was to evaluate the DR screening model in the Brunei-Muara District. Results from this study suggest that the DR screening model in Brunei-Muara is partially systematic. The main findings showed that key processes are in place at different stages of DR screening and treatment and that sufficient resources have been allocated to detect sight threatening diabetic retinopathy (STDR) at primary health centres (PHCs) and to treat STDR at the national eye centre (NEC). This was supported by the good DR annual screening uptake rates (77%) and low DR prevalence rates (5.8%) reported in this study. However, the lack of monitoring of both the implementation processes and screening effectiveness was viewed as key limitations in the programme. This was evident through process gaps observed throughout the DR screening and treatment pathway including the identification of patients for screening at PHCs, GP to DR referral process, referral for treatment processes to NEC and disease registers that were not integrated and lacked accuracy. This was also backed by evidence that DR screening coverage rates were low (56%) across all health centres. Based on a generic framework to analyse development of DR screening programmes used in this study, the existing screening model could be enhanced by improving screening coverage rates, universal access to DR treatment, trained and certified workforce, implementation of a call and recall system and systematic digital photography screening system. However, further studies are required before these recommendations could be implemented.
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Delfosse, Xavier. "Naines brunes et étoiles de très faible masse." Phd thesis, Université Joseph Fourier (Grenoble), 1997. http://tel.archives-ouvertes.fr/tel-00686419.
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Bien qu'elles dominent en nombre la population stellaire de la Galaxie, les étoiles de très faible masse et les naines brunes sont longtemps restées difficiles (voir impossibles) à observer, à cause de leur faible luminosité. Les progrès récents des techniques instrumentales (et en particulier des détecteurs infrarouges) permettent maintenant de s'y intéresser et de commencer à répondre à de nombreuses questions. Parmi celles-ci, deux sont particulièrement importantes et nécessitent une bonne détermination de la fonction de masse (nombre d'objets par intervalle de masse): l'influence de cette population sur la dynamique Galactique, et le comportement de la fonction initiale de masse à l'approche du régime naine brune. Ces objets permettent d'autre part des tests sévères de notre compréhension de la physique des objets dégénérés, et des atmosphères denses et froides dominées par les opacités moléculaires. Dans cette thèse, j'ai d'abord déterminé la fonction de luminosité (nombre d'objets par intervalle de luminosité) jusqu'à la limite étoiles-naines brunes, ce qui est la première étape de la construction de la fonction de masse. Pour cela j'ai utilisé le relevé DENIS (a Deep Near Infrared Southern sky survey qui est parfaitement adapté à la détection de ces objets, et étudié les biais importants de la fonction de luminosité introduits par le bruit. Au cours de ces travaux la première naine brune confirmée du champ a été découverte et une étude spectroscopique des naines brunes froides a été entreprise. Pour passer de cette fonction de luminosité à la fonction de masse, il est ensuite necessaire, 1- de corriger le biais important de la fonction de luminosité causé par les étoiles binaires, et 2- de disposer d'une bonne relation masse-luminosité. Ces deux étapes de la détermination de la fonction de masse passent par une étude de binarité. Une recherche systématique de binaires spectroscopiques a donc été entreprise dans cette thèse. Elle a révélé que le voisinage solaire (à moins de 9 pc) reste mal connu, et qu'un nombre important de compagnons y reste à découvrir (11 ont été mis en évidence ici). La distance des systèmes doubles non identifiés est également sous-estimée. Enfin, l'étude de la rotation des naines M du champ a été un sous-produit important du programme de recherche de binaires. Elle a clairement montré que l'activité chromosphérique de ces objets, depuis longtemps connue, est bien due à leur rotation. L'allongement du temps de freinage aux type spectraux les plus tardifs est ainsi demontrée jusqu'à des âges beaucoup plus grands, et jusqu'à des masses où les étoiles sont entièrement convectives.
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Delfosse, Xavier. "Naines brunes et étoiles de très faible masse." Phd thesis, Université Joseph Fourier (Grenoble ; 1971-2015), 1997. http://www.theses.fr/1997GRE10189.
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Bien qu'elles dominent en nombre la population stellaire de la Galaxie, les étoiles de très faible masse et les naines brunes sont longtemps restées difficiles à observer, à cause de leur faible luminosité. Les progrès récents des techniques instrumentales permettent maintenant de s'y intéresser et de commencer à répondre à de nombreuses questions. Parmi celles-ci, deux sont particulièrement importantes et nécessitent une bonne détermination de la fonction de masse : l'influence de cette population sur la dynamique galactique, et le comportement de la fonction initiale de masse à l'approche du régime naine brune. J'ai d'abord détermine la fonction de luminosité jusqu'à la limite étoiles-naines brunes, ce qui est la première étape de la construction de la fonction de masse. Pour cela j'ai utilisé le relevé infrarouge DENIS qui est parfaitement adapté à ce travail, et étudié les biais importants de la fonction de luminosité introduits par le bruit. Au cours de ces travaux l'une des deux premières naines brunes confirmées du champ a été découverte et une étude spectroscopique des naines brunes froides a été entreprise. Pour passer de cette fonction de luminosité à la fonction de masse, il est ensuite nécessaire de corriger le biais important de la fonction de luminosité causé par les étoiles binaires, et de disposer d'une bonne relation masse-luminosité. Une recherche systématique de binaires spectroscopiques a été entreprise dans cette thèse. Elle a révélé que le voisinage solaire reste mal connu, et qu'un nombre important de compagnons y reste à découvrir (11 ont été mis en évidence ici). La distance des systèmes doubles non identifiés est également sous-estimée. Enfin, l'étude de la rotation des naines M du champ a été un sous-produit important du programme de recherche de binaires. Elle a clairement montré que l'activité chromosphérique de ces objets est bien due à leur rotation. L'allongement du temps de freinage aux types spectraux les plus tardifs est ainsi démontré jusqu'à des âges beaucoup plus grands, et jusqu'à des masses où les étoiles sont entièrement convectives.
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Delorme, Philippe. "Les naines brunes dans les relevés grand champ." Phd thesis, Grenoble 1, 2008. http://www.theses.fr/2008GRE10155.
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Mon travail de recherche au cours de ces trois années de thèse sous la direction de Thierry Forveille et de Xavier Delfosse au laboratoire d'astrophysique de Grenoble a été consacré à la recherche de naines brunes dans un relevé grand champ de nouvelle génération que nous avons appelé le Canada-France Brown Dwarf Survey -CFBDS-. La thématique de ma thèse est centrée sur l'étude des naines brunes froides et la constitution d'un grand échantillon de naines brunes, comme base pour une analyse statistique photométrique et spectroscopique. Tétais chargé en premier lieu de la mise au point du pipeline d'analyse et de sélection des candidats au sein de la collaboration internationale dédiée à la recherche de naines brunes et de quasars à grand décalage vers le rouge. Dans le chapitre l, je fais un récapitulatif rapide de l'ensemble des avancées scientifiques dans le domaine des naines brunes avant la présente thèse. Le chapitre 2 présente le Canada- France Brown Dwarf Survey, qui fournit les données au coeur de mon travail, ainsi que notre stratégie d'analyse. Le chapitre 3 détaille le pipeline que j'ai mis en place pour identifier au mieux les naines brunes dans les images grand champs et présente une évaluation de ses performances. Les candidats ainsi identi és sur la base de leur photométrie sont présentés dans le chapitre 4. Dans ce chapitre je décris mes méthodes d'estimation des biais statistiques du CFBDS, ainsi que la fonction de luminosité des naines brunes du champ que nous en avons extraite. Enfin le chapitre 5 donne une revue des informations contenues dans le spectre des naines brunes. J'y présente ensuite les résultats issus de nos observations spectroscopiquesMy PhD research work, under the supervision of Thierry Forveille and Xavier Delfosse at the laboratoire d'astrophysique de Grenoble, is centered on identifying brown dwarfs in a new-generation wide-field survey, the Canada-France Brown Dwarfs Survey -CFBDS-. Its main goals are to identify cooler and low metallicity brown dwarfs for detailed study, and to assemble a large sample of more ordinary brown dwarfs for statistical analyses. My role, as the only full-time member of this international collaboration, included the programming of an analysis and selection pipeline to identify the rare brown dwarf candidates in the very large image database, as well as coordination of the internation collaboration. Chapter 1 summarizes the state of brown dwarf science at the start of this PhD. Chapter 2 presents the Canada-France Brown Dwarfs and our analysis strategy. Chapter 3 describes the pipeline 1 developed to optimally identify brown dwarfs (as well as high redshift quasars) candidates in the CFBDS images. This chapter also describes the Point Spread Function -PSF- fitting module which 1 added to the well known \textit{Source Extractor} image analysis package. Chapter 4 presents the resulting brown dwarf candidates, assesses the statistical biases of the CFBDS survey, and evaluates the associated field brown dwarfs luminosity function. Finally, Chapter 5 briefly reviews the the physical informations which can be extracted from brown dwarfs spectra, and examines in that light the spectra which we obtained for two dozen of our candidates. It ends with discussions of our disco very of the cooldest brown dwarf published to date, CFBDS0059, and of what is likely the first T subdwarf
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Delorme, Philippe. "Les naines brunes dans les relevés grand champ." Phd thesis, Université Joseph Fourier (Grenoble), 2008. http://tel.archives-ouvertes.fr/tel-00351010.
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Mon travail de recherche au cours de ces trois années de thèse sous la direction de Thierry Forveille et de Xavier Delfosse au laboratoire d'astrophysique de Grenoble a été consacré à la recherche de naines brunes dans un relevé grand champ de nouvelle génération que nous avons appelé le Canada-France Brown Dwarf Survey -CFBDS-. La thématique de ma thèse est centrée sur l'étude des naines brunes froides et la constitution d'un grand échantillon de naines brunes, comme base pour une analyse statistique photométrique et spectroscopique. J'étais chargé en premier lieu de la mise au point du pipeline d'analyse et de sélection des candidats au sein de la collaboration internationale dédiée à la recherche de naines brunes et de quasars à grand décalage vers le rouge. En tant que seul membre de la collaboration à travailler à plein temps sur le projet, j'ai toutefois été amené à m'impliquer fortement dans presque toutes les facettes du projet. En parallèle du travail scientique que je présente dans ce manuscript, j'ai consacré une part importante de ma thèse à la coordination du travail entre les différentes personnes impliquées dans le CFBDS de par le monde. Dans le chapitre 1, je fais un récapitulatif rapide de l'ensemble des avancées scientiques dans le domaine des naines brunes avant la présente thèse. Le chapitre 2 présente le Canada- France Brown Dwarf Survey, qui fournit les données au coeur de mon travail, ainsi que notre stratégie d'analyse. Le chapitre 3 détaille le pipeline que j'ai mis en place pour identier au mieux les quelques centaines d'astres qui nous intéressent parmi les dizaines de millions de sources que comptent les images du CFBDS. Ce chapitre met aussi en évidence les performances de la fonctionnalité d'analyse d'image par ajustement de fonction d'étalement du point -PSF- que j'ai adjointe au logiciel Source Extractor. Les candidats ainsi identiés sur la base de leur photométrie sont présentés dans le chapitre 4. Dans ce chapitre je décris mes méthodes d'estimation des biais statistiques du CFBDS, ainsi que la fonction de luminosité des naines brunes du champ que nous en avons extraite. Enn le chapitre 5 donne une revue détaillée des informations contenues dans le spectre des naines brunes. J'y présente ensuite nos observations spectroscopiques ainsi que les résultats associés, notamment la découverte d'absorption par l'ammoniac dans le spectre de la naine brune la plus froide publiée à ce jour, CFBDS0059, ainsi que la découverte de la première naine T sous-métallique.
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Guéno, Josselin. "Détermination et différenciation sexuelle chez les algues brunes." Electronic Thesis or Diss., Sorbonne université, 2019. http://www.theses.fr/2019SORUS629.
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Chez de nombreux eucaryotes, le sexe est déterminé génétiquement par des chromosomes sexuels tels que XY, ZW et UN. Chez de nombreuses algues brunes, le sexe est déterminé génétiquement par les chromosomes IJ et V, plus précisément par la présence de régions spécifiques U (femelles) ou V (mâles) sur ces chromosomes. Un gène candidat pour la détermination du sexe mâle a été découvert dans la région spécifique du chromosome V. Ce gène appartient à la famille des gènes codant pour les protéines à domaine HMG, qui intervient notamment dans la détermination du sexe chez les mammifères et les champignons. Bien que la détermination du sexe soit déclenchée par un gène présent sur les chromosomes sexuels, la différenciation sexuelle est principalement déterminée par l'expression de gènes sexuellement biaisés au niveau des autosomes, qui sont donc présents chez les mâles et les femelles, mais dont le niveau d'expression diffère entre les deux sexes. Le but de ma thèse était d'améliorer notre compréhension des mécanismes qui sous-tendent la détermination et la différenciation du sexe chez les algues brunes. J'ai étudié la protéine HMG liée à la région spécifique mâles chez Ectocarpus, par des techniques de double hybride en levures et de DAP-seq. Par ailleurs, afin de comprendre comment les programmes de développement sexuel sont établis et régulés chez les algues brunes, j'ai examiné les paysages chromatiniens entre les deux sexes à différentes échelles que ce soit au niveau du génome, au niveau chromosomique et au niveau des gènes sexuellement biaisés par une méthode ChlP-seq contre des modifications post-traductionnelles d'histoneIn many eukaryotes, sex is genetically determined by sex chromosomes such as XY, ZW and IJIV. In many brown algae, sex is genetically determined by the U and V chromosomes, more precisely by the presence of U (female) or V (male)-specific regions on these chromosomes. A candidate gene for male sex deterrnination has been discovered at the V (male)-specific region. This gene belongs to the HMG-domain protein coding gene family, that is involved in gender determination in mammals and fungi. Although sex determination is triggered by a gene present on the sex chromosomes, sexual differentiation is mainly driven by autosomal sex-biased gene expression, which are therefore present in both males and females. My thesis's goal was to increase our understanding of the mechanisms underlying sex determination and differentiation in brown algae. I studied the HMG protein linked to the (male)-specific regions in Ectocarpus, by a yeast two hybrid method and DAP-seq. In order to understand how sex-specific developmental programs are established and regulated in the brown algae, I examined the sex- and chromosome-specific chromatin landscapes by a ChlP-seq method, and explored variant lines that are impaired in the expression of their sex-specific developmental programs
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Brune, André [Verfasser]. "Elektrisch erregte Synchronmaschinen als Fahrantriebe / André Brune." Garbsen : TEWISS - Technik und Wissen GmbH, 2019. http://d-nb.info/1176166190/34.
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Le, Bail Aude. "Morphogenèse précoce de l'algue brune Ectocarpus siliculosus." Paris 6, 2009. http://www.theses.fr/2009PA066477.
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Cette thèse initie l’étude de la morphogenèse de l’algue brune modèle Ectocarpus siliculosus, qui est formée d’un filament primaire unisérié comportant des embranchements. Dans un premier temps, l’étude du patron de développement précoce a mis en évidence une croissance apicale des filaments suivie d’une différenciation cellulaire centripète aboutissant à deux types de cellules. Ces données ont ensuite été utilisées pour modéliser le développement d’E. Siliculosus grâce à une approche par simulation informatique, révélant qu’aux stades très précoces, la connaissance par chaque cellule de l’identité des cellules voisines est suffisante pour créer des filaments identiques à ceux observés en culture. Cette hypothèse est appuyée par l’étude du mutant de morphogenèse étoile, qui possède une capacité de prolifération cellulaire accrue et met en évidence l’importance de protéines transmembranaires à domaine Notch dans la mise en place du patron de développement. En parallèle, la phytohormone auxine a été détectée dans les filaments avec une concentration maximale aux apices, et semble jouer un rôle dans la morphogenèse de l’algue en procurant aux cellules une information de position globale permettant la mise en place du patron d’embranchements. De plus, l’analyse du génome a permis de montrer qu’E. Siliculosus possède la machinerie enzymatique nécessaire à la synthèse de l’acide indole-3-acétique. La morphogenèse d’E. Siliculosus pourrait ainsi requérir l’intervention de deux types de mécanismes, une signalisation paracrine faisant intervenir des protéines transmembranaires à domaine Notch, et une signalisation à distance par l’intermédiaire d’un gradient d’auxine.
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Matumba, Tshifhiwa Given. "Genetics and thermal biology of littorinid snails of the genera Afrolittorina, Echinolittorina and Littoraria (Gastropoda: Littorinidae) from temperate, subtropical and tropical regions." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/d1001953.
Full textAbstract:
With the anticipated effects of climate change due to global warming, there is concern over how animals, especially ectotherms, will respond to or tolerate extreme and fluctuating environmental temperature stress. Littorinid snails are intertidal ectotherms that live high on the shore where they experience both extreme and variable conditions of temperature and desiccation stress, and are believed to live close to their tolerance limits. This study investigated the thermal biology of littorinid snails of the genera Afrolittorina, Echinolittorina and Littoraria from temperate, subtropical and tropical regions in South Africa and Brunei Darussalam using thermal tolerance, heart function, and proteome approaches. The effects of conditions, such as rate of change in temperature, acclimation, heat shock, season and starvation were also tested. In addition, the evolutionary relationships and genetic diversity between and within the South African Afrolittorina spp. were investigated using mitochondrial and nuclear markers. Genetic results confirmed that these are two distinct species, with the brown to black A. knysnaensis predominant in the cool-temperate region of South Africa and the pale blue-grey A. africana in the subtropical region. There was low genetic variation and differentiation within each species, suggesting high gene flow among populations as a result of the effects of ocean currents on the dispersal of their planktotrophic larvae. Tests using exposure to high temperatures revealed differences in the thermal tolerances, heart performance and protein profiles of species from different latitudes, regions and zones on the shore. Thermal tolerance conformed to expectations, with clear, statistically significant trends from high tolerance in subtropical species to lower tolerance in temperate species. However, for Afrolittorina spp., there were no significant differences in the thermal tolerances of conspecifics from different regions, though there was a significant difference in thermal tolerance between juveniles and adults. Overall, adults of all species showed higher thermal tolerances than juveniles. Although lethal temperatures for these species were higher in summer than winter, laboratory acclimation had no effect on heat coma temperatures. All species showed some regulation of heart rate, with a degree of independence of heart rate from temperature across mid-range temperatures. The tropical species showed quick induction and good regulation of heart rate followed by the subtropical and temperate species, which displayed mixed responses including regulation, partial regulation and lack of regulation. Overall, tropical Echinolittorina spp. showed good regulation, while the subtropical E. natalensis and Littoraria glabrata exhibited a mixture of partial regulation and regulation. The subtropical/temperate Afrolittorina spp. showed high individual variability, some animals exhibiting regulation, while others did not. These effects seem to be largely phylogenetically determined as there were no differences in the heart rate responses of Afrolittorina spp. from different regions. The temperatures at which heart rate became independent of temperature (thermoneutral zone) were within the range experienced under natural conditions. In addition, there were differences in Arrhenius breakpoint and endpoint temperatures, showing a trend from higher in tropical animals to lower for temperate animals. Conditions such as acclimation, heat shock and starvation had little or no effect on heart performance. However, a slow increase in temperature induced good regulation of heart rate with noticeable shifts of breakpoints and endpoints for Afrolittorina spp. Lastly, there were differences in the proteome responses between and within Afrolittorina spp. as a function of species, size and treatment. Although both large and small A. knysnaensis had a greater number of protein spots in their proteome than A. africana (though the difference was not significant), the later showed significantly higher differential expression of certain proteins following heat stress. In addition, juveniles of both species displayed greater numbers of protein spots in their proteome than adults. The results indicate a difference in the physiological and biochemical responses (i.e. adaptations) of these snails to temperature, and this seems to relate to differences in biogeography, phylogeny, species identity and ecology. The ability to regulate heart rate is phylogenetically determined, while thresholds and lethal limits correspond to biogeography and species ecology. The proteome seems to correspond to species ecology. The results also indicate that these littorinids can tolerate high temperature stress and in this respect they are well suited to life in the intertidal zones or habitats where temperature and other stresses or conditions are extreme and can change abruptly. However, the limited ability of these snails to acclimate to different temperatures suggests that they are already living close to their tolerance limits with small safety margins or narrow thermal windows and so may be vulnerable to small rises in substratum temperature and/or solar radiation.
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Ebikeme, Charles E. "Amino acid transporters and amino acid metabolism in trypanosoma brucei brucei." Connect to e-thesis, 2007. http://theses.gla.ac.uk/55/.
Full textAbstract:
Thesis (Ph.D.) - University of Glasgow, 2007.Ph.D. thesis submitted to the Division of Infection and Immunity, Institute of Biomedical and Life Sciences, University of Glasgow, 2007. Includes bibliographical references.