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Published: 4 June 2021
Last updated: 11 March 2023

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1

Aldén, Gustaf. "A pilot framework for BRM training." Thesis, Linnéuniversitetet, Sjöfartshögskolan (SJÖ), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-95155.

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Human error has been a key factor in grounding- and collision incidents in the past and continues to present a challenge to the maritime industry in the present day. The feasibility of a pilot framework for Bridge Resource Management (BRM) training lies at the heart of this study, its objective being to gauge the possibility of the construction of such a model. The result is thought to open up for further research and highlight the most relevant and effective BRM tools that can be used, by the bridge team, to prevent collision and grounding. The study was carried out in two stages. Firstly, four key personnel within the shipping industry were interviewed. These respondents were tasked with prioritising what they regarded as the most effective BRM tools. Secondly, the effectiveness of these tools was tested on marine incident cases. A document analysis was carried out on six collision and grounding cases, as investigated by the Marine Accident Investigation Branch (MAIB). The majority of the respondents were in agreement regarding which three BRM tools they regarded as the most relevant and effective. The result from the interviews was repeated in the result from the document analysis.  The conclusions that were drawn are that: it is possible to construct a pilot framework for BRM training and it is also possible to measure the effectiveness of the BRM tools. Additionally, suggestions for further research that arose from this thesis pertain to the study of the relationship between different BRM tools.
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2

Bock, Vanessa Leonie. "The Role of Brm, Brg-1, Snail 1 and Snail 2 in the Progression of Non-Melanoma Skin Cancer." Thesis, The University of Sydney, 2008. http://hdl.handle.net/2123/4091.

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Non-melanoma skin cancer (NMSC) is the most common human cancer worldwide. Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) make up almost all NMSC. SCC usually arises from actinic keratosis (AK) as a result of exposure to sunlight. SCC and AK provide a useful clinical model to investigate changes involved in the progression of NMSC. This project examines the expression of Brm, Brg-1, Snail 1 and Snail 2 in the progression of NMSC. Brm and Brg-1 are subunits of the SWI/SNF chromatin-remodelling complex which is involved in regulating the access of cell machinery to DNA by altering the structure of chromatin. It has been suggested that loss of this function is involved in carcinogenesis as the cell is unable to access to DNA normally in order to repair mutations or activate apoptosis. The loss of Brm or Brg-1 has been described in several human cancers. Snail 1 and Snail 2 are zinc-finger transcription factors that are known for their role in epithelial to mesenchymal transition (EMT), a process vital to embryological development. Increased expression of these factors leads to a loss of cell-cell adhesion and a migratory phenotype and has been described in some human cancers. In this project, double-label immunohistochemistry was used to determine the relative expression of these proteins in human SCC, BCC, AK and normal skin. The expression of Snail was unable to be determined due to poor specificity of the antibodies used. The expression of both Brm and Brg-1 proteins was found to be dramatically and consistently decreased in SCC and BCC when compared to normal skin and AK. This loss of Brm and Brg-1 occured as the tumour progressed from benign AK to malignant SCC. This finding suggests that the loss of either Brm or Brg-1 constitutes a key step in carcinogenesis. The results of this study identify Brm and Brg-1 as putative tumour suppressors involved in the progression of non-melanoma skin cancer from benign to malignant.
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3

Bock, Vanessa Leonie. "The Role of Brm, Brg-1, Snail 1 and Snail 2 in the Progression of Non-Melanoma Skin Cancer." University of Sydney, 2008. http://hdl.handle.net/2123/4091.

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Master of Medicine
Non-melanoma skin cancer (NMSC) is the most common human cancer worldwide. Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) make up almost all NMSC. SCC usually arises from actinic keratosis (AK) as a result of exposure to sunlight. SCC and AK provide a useful clinical model to investigate changes involved in the progression of NMSC. This project examines the expression of Brm, Brg-1, Snail 1 and Snail 2 in the progression of NMSC. Brm and Brg-1 are subunits of the SWI/SNF chromatin-remodelling complex which is involved in regulating the access of cell machinery to DNA by altering the structure of chromatin. It has been suggested that loss of this function is involved in carcinogenesis as the cell is unable to access to DNA normally in order to repair mutations or activate apoptosis. The loss of Brm or Brg-1 has been described in several human cancers. Snail 1 and Snail 2 are zinc-finger transcription factors that are known for their role in epithelial to mesenchymal transition (EMT), a process vital to embryological development. Increased expression of these factors leads to a loss of cell-cell adhesion and a migratory phenotype and has been described in some human cancers. In this project, double-label immunohistochemistry was used to determine the relative expression of these proteins in human SCC, BCC, AK and normal skin. The expression of Snail was unable to be determined due to poor specificity of the antibodies used. The expression of both Brm and Brg-1 proteins was found to be dramatically and consistently decreased in SCC and BCC when compared to normal skin and AK. This loss of Brm and Brg-1 occured as the tumour progressed from benign AK to malignant SCC. This finding suggests that the loss of either Brm or Brg-1 constitutes a key step in carcinogenesis. The results of this study identify Brm and Brg-1 as putative tumour suppressors involved in the progression of non-melanoma skin cancer from benign to malignant.
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4

Farrell, Andrew William. "The Role of Brm in Non-­‐Melanoma Skin Cancer Progression." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/16438.

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Background: Australia has the highest incidence of non-melanoma skin cancer (NMSC) in the world. These cancers are predominantly caused by exposure to ultraviolet radiation (UVR) in sunlight. Brm is an ATPase subunit that drives chromatin remodelling via the SWI/SNF complex. Thus, Brm is able to regulate access to transcription factors and repair enzymes to DNA, in addition to cell division. The loss of Brm has been observed in several cancer types, where its loss correlates with decreased patient survival. The loss of Brm has been identified in NMSC, but not pre-malignant lesions, suggesting Brm plays a role in the progression of a benign skin lesion into a malignant skin cancer. Brm-deficient mice also harbour excessive levels of epidermal hyperplasia as well as heightened tumour incidence following UVR as compared to mice with wildtype Brm. Moreover, a novel hotspot mutation of Brm (Q203K) has also been discovered in 17% of NMSC studied, which was the first mutation of Brm discovered in any type of cancer. Aims: This thesis aims to study the function of the Q203K mutation as compared to the loss of Brm in several key aspects of keratinocyte responses to UV-induced DNA damage: proliferation, cell cycle regulation, UVR-induced cell death and DNA repair. Methods: The loss of Brm was studied with keratinocytes grown ex vivo from neonatal Brm-/- mice and compared to keratinocytes grown from Brm+/+ mice. Further, a human keratinocyte cell line, HaCaT was also studied, in combination with Brm miRNAs to knockdown Brm expression in these cells. The overexpression of either wildtype or Q203K Brm was also studied in HaCaTs. These cells were treated with UV, and their responses were observed using assays for cell growth, cell death, cell cycle regulation and DNA repair. Results: In neonatal mouse keratinocytes, as well as HaCaT cells, the loss of Brm expression led to an altered cellular response to UVR. Cells lacking Brm exhibited increased proliferative potential following UVR due to a reduced time spent in G1 cell cycle arrest. Further, Brm-deficient cells displayed increased formation of UVR-induced cyclobutane pyrimidine dimers (CPDs) in the dark. Interestingly, when Brm was knocked down in the immortalised human keratinocyte cell line HaCaT, these cells were not as sensitive to the loss of Brm in combination with UVR, and showed less prominent effects on both cell cycle regulation and CPD formation. It was hypothesised that primary neonatal keratinocytes were more sensitive to UVR due to these cells being naïve, whereas HaCaT cells already exhibit several UVR-induced mutations, such as that of p53. Therefore, the loss of Brm in mouse neonatal keratinocytes was more catastrophic to the cell. Lastly, the mutation of Q203K did not lead to increased cellular sensitivity to UVR, suggesting the presence of this mutation in NMSC was most likely non-functional. However, increasing levels of Brm in HaCaT cells did lead to enhanced levels of cell viability at high density, which the Q203K mutation was able to reverse, suggesting Q203K does display some functionality, and thus may play a role in other functions not studied in this thesis. Conclusions: The loss of Brm but not the Q203K mutant in combination with UVR is enough to cause increased cellular sensitivity in the cell, leading to the proliferation of cells whilst harbouring DNA damage via defective cell cycle checkpoints. This would likely lead to heightened levels of mutations in the cell, and increased carcinogenesis downstream, as previously witnessed in Brm-deficient mice. The Q203K mutation was not comparable to the loss of Brm, and this thesis suggests that the Q203K mutation in NMSC is not likely to contribute to increased carcinogenesis, however further testing would have to be conducted to fully determine this.
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5

Oddgeirsson, Edmark Henrik. "Varje fartyg är unikt : Sjöbefäls upplevelser av BRM och hur det tränas." Thesis, Linnéuniversitetet, Sjöfartshögskolan (SJÖ), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-82489.

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Bridge Resource Management (förkortat BRM) är idag en naturlig del av handhavandet av fartyg, med syfte att öka säkerheten. Olyckorna till sjöss minskar däremot inte i den takt som de borde. Studien har därför ställt frågan om hur aktiva sjöbefäl upplever att träning i BRM kan förbättras för att bidra till ökad säkerhet, med icke-tekniska förmågor som teoretisk utgångspunkt. Slutsatsen är att inget fartyg är det andra likt när det gäller arbetet med BRM, och förhållandevis abstrakta egenskaper hos besättningen som inställning och beteende i kombination med praktisk nautisk kompetens och erfarenhet är nyckelkomponenter för fartygets säkra framförande. Varje tillfälle för BRM-träning bör också hanteras som unikt, framför allt utifrån deltagarnas specifika behov och bakgrund.
Bridge Resource Management (in short BRM) is today a natural part of ship handling, with its purpose of enhancing safety. The accidents, on the other hand, are not declining by a desired rate. This study has therefore posed the question of how working deck officers experience training in BRM and how it is contributing to safety. The theoretical basis is the concept of non-technical skills. The conclusion is that every vessel is unique when it comes to BRM. Seemingly abstract faculties as attitude and behavior shown by the crewmembers combined with practical, nautical competence and experience are key factors for safe ship handling. Every moment of BRM-training should be a unique event, and therefore arranged keeping the specific needs and background of the participants in mind.
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6

SCATTOLINI, DANIELE. "LA GESTIONE DELLA RELAZIONE NELLA SUPPLY CHAIN: DAL TRADE MARKETING AL BRM." Doctoral thesis, Università Politecnica delle Marche, 2016. http://hdl.handle.net/11566/243101.

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Il presente lavoro, sviluppato nell’ambito del dottorato di ricerca cofinanziato dal Gruppo Fileni, riguarda il rapporto tra l’industria e la distribuzione; nello specifico, si sviluppa nell’osservare quali azioni l’impresa di produzione può intraprendere per migliorare la relazione e la gestione della relazione stessa con le imprese commerciali. Nella tesi l’attenzione si è concentrata sul’evoluzione del marketing tradizionale, verso nuove forme di marketing relazionale, esaminando in particolare il trade marketing. L’aspetto innovativo è rappresentato, invece, dalle possibilità applicative del Buyer Relationship Management (BRM), evoluzione del CRM, con specifico riferimento al Gruppo Fileni. L’obiettivo principale è, pertanto, comprendere sotto quali condizioni organizzative e sotto quale approccio manageriale sia possibile implementare un percorso di sviluppo in grado di far conseguire alle imprese industriali risultati utili. La ricerca ha permesso di portare avanti, oltre ad una riflessione teorica sul rapporto industria-distribuzione, due indagini empiriche: la prima, basata sul metodo del caso di studio multiplo, ha rappresentato il supporto di verifica per l’analisi della tematica del trade marketing, analizzando quattro differenti best practices di aziende di calibro nazionale e internazionale; la seconda, basata sul metodo del caso di studio singolo, in una logica di action research, ha riguardato un esempio di percorso evolutivo da seguire per creare valore nella supply chain. Le due analisi presentano interessanti implicazioni teoriche e operative. A livello teorico, la prima ha consentito di arricchire con interessanti contributi la tematica del trade marketing; la seconda, invece, di concettualizzare un modello innovativo, il BRM, capace di avanzare gli studi in materia di CRM. A livello operativo, invece, le indagini offrono utili indicazioni ai manager sul percorso da seguire per migliorare la relazione e, soprattutto, la gestione del rapporto con le imprese commerciali.
This work, developed within PhD studies co-financed by the Fileni Group, addresses the issue of the relationship between the supplier and the retailer. More specifically, the present study investigates which supplier actions are suitable for improving the management of relationships with retailers. This thesis focuses on the evolution of the traditional concept of marketing towards new forms of relationship marketing, examining in particular trade marketing. The innovative aspect of this work is the possible application to the Fileni Group of Buyer Relationship Management (BRM), which is a development of CRM. The main objective is, from the supplier’s perspective, to understand which organizational conditions and managerial approach will encourage progressive development and hence lead to good performance. In addition to a theoretical discussion on the supplier-retailer relationship, this work also allowed two empirical studies to be carried out: the first, based on the multiple case study method, confirms the relevance of the trade marketing literature and analyzes four different best practices adopted by national and international companies; the second, which uses the single case study method and ongoing action research, presents an example of development which can create supply chain value. The two analyses have interesting theoretical and operational implications. The first empirical analysis has, to a certain extent, contributed to existing literature by updating studies on the subject of trade marketing, while the second study has allowed an innovative model, the BRM, to be implemented, which is capable of furthering CRM studies. From a more operational point of view, the analyses may provide supplier managers with considerable insight not only into how to enhance relationships with retailers but, above all, into how to improve the management of these relationships.
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7

Sut, Caroline. "Détermination des prédicteurs de sévérité des effets indésirables receveurs au cours des transfusions de concentrés plaquettaires." Thesis, Lyon, 2017. http://www.theses.fr/2017LYSES061/document.

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La transfusion sanguine est une thérapeutique indispensable pour laquelle il n’existe pas actuellement de substitut. La transfusion de produits sanguins labiles est dans la grande majorité des cas très bien tolérée mais elle peut être à l’origine d’effets indésirables chez les receveurs (EIR) notamment de type inflammatoire. Ceci dépend de facteurs liés aux produits eux-mêmes et/ou aux receveurs de par leur prédisposition génétique et de leur état clinique. Les concentrés plaquettaires (CP) sont la principale source de manifestations inflammatoires et/ou allergiques. Ceci est notamment dû, en partie, à la capacité des plaquettes à sécréter une multitude de molécules ayant une activité inflammatoire. De plus, les processus de collecte, de préparation et de conservation induisent un stress vis-à-vis des cellules, qui peut activer les plaquettes et donc induire la production de produits inflammatoires dans les CP. Le but de ce travail de thèse a été dans un premier temps d’identifier les molécules les plus impliquées dans les manifestations inflammatoires. Le sCD40L en particulier est identifié comme étant largement impliqué dans les EIR après transfusion de CP, mais pas systématiquement. Aussi, la composante inflammatoire de ces réactions est multifactorielle. De plus, nous avons évalué le potentiel inflammatoire des CP sur l’endothélium vasculaire. Des différences d’activation des cellules endothéliales, dans un modèle in vitro, ont été observées lorsqu’elles sont en présence de surnageants de CP ayant induits un EIR. Ce travail de thèse poursuit l’effort entrepris par notre équipe de recherche, en vue de prédire la survenue d’EIR et de préciser les mécanismes qui influencent la physiopathologie plaquettaire transfusionnelle ; un corollaire de ces travaux est ainsi d’optimiser les processus de production et de conditionnement des CP transfusés afin de réduire ces réactions inflammatoires
Blood transfusion is an indispensable therapy for which there is currently no substitute. Transfusion of blood products is in the great majority of cases very well tolerated but it can be at the origin of serious adverse reactions (SARs), notably of inflammatory reactions. This depends on the factors related to the products themselves and/or to the recipients, their genetic predisposition and clinical condition. Platelet concentrates (PCs) are the main source of inflammatory and/or allergic manifestations. This is due, in part, to the ability of platelets to secrete a multitude of molecules with inflammatory activity. In addition, the collection, processing and storage conditions induce stress on cells, which can activate platelets and thus induce the production of inflammatory products in PCs. The purpose of this work is to identify the molecules involved in inflammatory manifestations. sCD40L was identified as being involved in SARs after PCs transfusion, but not systematically. Also, the inflammatory component of these reactions is multifactorial. In addition, we evaluated the inflammatory potential of PCs on the vascular endothelium. Differences in endothelial cell activation, in an in vitro model, were observed when they were in the presence of PC supernatants involved in SARs. This thesis work continues the effort undertaken by our research team to predict the occurrence of SARs and to clarify the mechanisms that influence transfusional platelet physiopathology; a corollary of this work is to optimize the production and conditioning process of PCs transfused in order to reduce these inflammatory reactions
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8

Zhang, Min. "The role of SWI/SNF in regulating smooth muscle differentiation." Thesis, Connect to resource online, 2009. http://hdl.handle.net/1805/2024.

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Thesis (Ph.D.)--Indiana University, 2009.
Title from screen (viewed on December 1, 2009). Department of Cellular and Integrative Physiology, Indiana University-Purdue University Indianapolis (IUPUI). Advisor(s): B. Paul Herring, Anthony B. Firulli, Frederick M. Pavalko, Simon J. Rhodes. Includes vitae. Includes bibliographical references (leaves 138-149).
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9

Krzystyniak, Joanna. "Epigenetic modulation of intestinal homeostasis and tumorigenesis by Brm SWI/SNF chromatin remodelling factor." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/73083/.

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SWI/SNF chromatin remodelling complexes are one of the well-characterized cellular machineries capable of regulation of gene expression. Numerous lines of evidence indicate that SWI/SNF complexes are involved in a wide range of cellular processes and the maintenance of homeostasis whereas aberrant expression of those proteins contributes towards cancer development. Colorectal cancer remains one of the most clinically significant cancers due to its high incidence in developed countries and previous studies have demonstrated that SWI/SNF complexes are aberrantly regulated in a significant proportion of patients with this disease. However, whilst the sequence of molecular events leading to CRC has been well-established, the role of SWI/SNF chromatin remodelling complex ATPase subunits Brm and its paralogue Brg1 in the colorectal tumorigenesis remains elusive. The chromatin remodelling catalytic subunit Brm has been found to interact with the Notch pathway effectors ICD-22 and CBF-1 and also to be necessary for expression of the Wnt target gene CD44 and for Rb-mediated cell cycle arrest. In this PhD thesis, the potential of Brm to modulate Wnt-driven intestinal tumorigenesis was addressed. Initially, a murine model carrying constitutively deleted Brm was used to assess the consequences of this loss on homeostasis of the small intestinal and colonic epithelia. The effects of Brm deficiency were also examined in the context of Wnt-activated epithelium via conditional loss of Apc. Additionally, the effect of concomitant loss of Brm and Brg1 was addressed in the contexts of both normal homeostasis and aberrant Wnt signalling. The results presented here demonstrate that Brm plays an important role in the small intestine by regulating the distribution of proliferating cells and cell fate decisions mediated through Notch pathway effectors. Furthermore, Brm deficiency was found to modulate intestinal phenotype of Wnt activation through the attenuation of the Wnt transcriptional programme and the suppressed expression of the intestinal stem cell marker Olfm4. Thus while Brg1 has been widely characterized as a bone fide tumour suppressor, the function of Brm continues to remain elusive especially in the light of contrasting effects co-mediated by Brm on proliferation, differentiation and gene expression. Taken together, these results elucidate the tissue-specific role of Brm, the catalytic subunit of SWI/SNF chromatin remodelling complex, on both normal intestinal homeostasis and acute activation of Wnt pathway while the extent of these Brm-dependent effects depend upon the gradient of Wnt signalling throughout the epithelium of small and large intestine.
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10

Pantak, N. "Hitting the target but missing the point : Merseyside Police's response to the BRM satisfaction gap." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3010080/.

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The study is an evaluation of how Merseyside Police attempted to narrow the Black and Racial Minority (BRM) satisfaction gap, as measured by the Home Office performance indicator. The research considers the sense with which both police officers and, more importantly, victims made of the policies and processes used. It asks whether this activity resulted in an improvement to the service being provided, therefore benefitting the victim, or in the construction of performance data thereby benefitting the organisation. The research was undertaken between 2011 and 2015 and completed as a case study. It involved the views of those people within Merseyside Police who were responsible for the design and implementation of policy along, with some of those responsible for delivering the service to the public. The research also includes the narrative of victims who had taken part in Merseyside Police’s monthly victim satisfaction survey. The BRM satisfaction gap was initially proposed by the Macpherson Report, which had examined the murder of black teenager Stephen Lawrence. It was one of ten performance indicators intending to monitor and assess whether trust and confidence in the police was improving within BRM communities. Previous research had identified factors other than the quality of police contact as influencing a person’s level of satisfaction. However, this research shows how the BRM satisfaction gap was treated as a single subject by Merseyside Police, who chose to focus purely on service delivery to improve victim satisfaction. Warnings regarding statistical relevance of the BRM satisfaction gap, along with concerns as to whether the victim satisfaction survey was fit for purpose, were ignored in their efforts to ensure the performance indicator was on target. The research highlights how New Public Management (NPM) principles of performance management were used to produce organisational focus and develop a system which closely tracked the service provided to BRM victims by individual officers. However, it shows that although it resulted in a good knowledge amongst senior officers, this was not embedded amongst those delivering the service. Instead, reporting officers developed their own working practices to deliver Merseyside Police’s required ‘Gold Service’ to BRM victims, whilst many victims remained confused and frustrated with the service provided. Merseyside Police did statistically narrow the BRM satisfaction gap. However, the research highlights the influence of performance construction and questions whether the recorded improvement in performance was as result of an improved service or was manufactured by gaming techniques. Although the BRM satisfaction gap was intended to measure trust and confidence, the research concludes this was never a consideration for Merseyside Police who, instead, focussed their efforts on improving their performance indicator.
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11

Bonicoski, Orival. "Gerenciamento dos cuidados de enfermagem em uma comunidade jesuítica da província do brasil meridional (BRM)." Universidade do Vale do Rio dos Sinos, 2013. http://www.repositorio.jesuita.org.br/handle/UNISINOS/4508.

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O presente estudo teve como objetivo a implantação do gerenciamento dos cuidados de enfermagem na comunidade João Paulo II da Província do Brasil Meridional (BRM), localizada em Florianópolis/SC, como unidade piloto do estudo. Descreve-se características demográficas, clínicas e de saúde, identificando as necessidades de saúde, sistematizando os cuidados prestados à saúde e construindo um fluxograma dos acompanhamentos clínicos desta comunidade. Caracteriza-se como um estudo de intervenção, com enfoque quantitativo. Trata-se de uma comunidade de 13 religiosos jesuítas, com idades variadas e atividades laborativas diversificadas. O gerenciamento das ações de enfermagem implantadas centraliza-se no Instituto São José, Casa de Saúde dos jesuítas da BRM em São Leopoldo/RS. A idade variou de 33 a 82 anos, quanto à procedência, a maioria são descendentes do estado do Rio Grande do Sul. Na escolaridade, aparece o ensino superior com maior evidência. Em relação à categoria religiosa, tiveram-se Padres, Irmãos e Escolásticos, com ocupações diversificadas, de acordo com a categoria religiosa e missão recebida. O fato de serem proprietários da instituição, faz com que a jornada de trabalho seja máxima estabelecida por lei. Outro ponto pesquisado foi o lazer, esse aparece entre todos de forma variada. Nos dados clínicos, no que se refere ao Índice Massa Corporal (IMC) e a Mini Avaliação Nutricional (MAN), foram encontrados jesuítas, abaixo do peso, risco de desnutrição, desnutridos, com sobrepeso e obesos. Também apareceu o hábito de fumar e de ingerir álcool. . Poucos realizaram a prática de atividade física. Os diagnósticos clínicos que mais apareceram foi de HAS e DM2. A maioria não tem médico assistente e não realizam exames médicos periodicamente. Nenhum dos pesquisados possuem o esquema vacinal de forma completa e atualizada. No uso das redes de apoio em saúde, à procura ocorre entre os postos de saúde, farmácias, centro de exames diagnósticos e radiológicos e clinica de fisioterapia. As medicações são gerenciadas pelos próprios sujeitos pesquisados e prescritas de acordo com os diagnósticos clínicos. Na auto percepção em saúde, a avaliação ficou entre “boa” e “muito boa”, o que leva a crer, que todos tem uma percepção positiva de sua saúde. A espiritualidade dos jesuítas, demonstrou que, há uma relação intima entre o transcendente e o imanente. De acordo com as situações de saúde dos Jesuítas, enumeraram-se diagnósticos de enfermagem e intervenções de acordo com a taxonomia da Classificação Internacional das Práticas de Enfermagem em Saúde Coletiva (CIPESC), permitindo elaborar um plano de cuidados de enfermagem para a comunidade João Paulo II e outro de caráter individual. Esse plano de cuidados deve ser acompanhado periodicamente pelo enfermeiro, através de um fluxograma. Outras situações encontradas como, não realizar exames médicos periódicos; não possuir médico assistente; não usufruir de redes de apoio, não ter orientações sobre espiritualidade e o uso de medicações, não são contemplados com os diagnósticos e intervenções da CIPESC. Espera-se, com essas intervenções, facilitar a elaboração de um instrumento para uma boa gestão em saúde dos Jesuítas das demais residências da Província BRM.
The present study aimed to the implementation of management of nursing care in the community John Paul II the Province of Southern Brazil (BRM), located in Florianópolis / SC as pilot plan study. Describes the demographic, clinical and health by identifying health needs, streamlining the health care and building a flowchart of clinical accompaniments of this community. Characterized as an intervention study with quantitative approach. It is a community of 13 Jesuits, of varying ages and diverse work activities. The management of nursing actions implemented focuses on the Institute of St. Joseph, Jesuit House Health of BRM in São Leopoldo / RS. The age ranged from 33 to 82 years, on the merits, the majority are descendants of the state of Rio Grande do Sul The members have higher education appears more clearly. Regarding the religious category, had to priests, brothers and scholastics, with diverse occupations, according to the religious category and mission received. The fact that they are owners of the institution, makes the workday is maximum established by law. Another point was researched leisure, this appears among all so varied. Clinical data in relation to Body Mass Index (BMI) and the Mini Nutritional Assessment (MNA), were found jesuits, underweight, risk of malnutrition, undernourished, overweight and obese. Also appeared in the habit of smoking and drinking alcohol. . Few realized the physical activity. Clinical diagnoses that appeared was more hypertension and T2DM. Most have no doctor and do not conduct medical examinations periodically. None of the respondents have the vaccination schedule so complete and updated. The use of support networks in health, looking occurs between health centers, pharmacies, examination center and radiological diagnostics and physiotherapy clinic. Medications are managed by the subjects researched and prescribed according to clinical diagnoses. In self-perception in health assessment was between "good" and "very good", which leads us to believe that everyone has a positive perception of their health. The spirituality of the Jesuits, has shown that there is an intimate relationship between the transcendent and the imminent. According to the health situation of the Jesuits, were listed nursing diagnoses and interventions according to the taxonomy of the International Classification of Nursing Practice in Public Health (CIPESC), allowing a plan of nursing care to the community John Paul II and another individual character. This care plan must be monitored periodically by a nurse, via a flowchart. Other conditions as found, do not perform periodic medical examinations; has no doctor, do not take advantage of support networks, not guidelines on spirituality and the use of medications, are not included with the diagnoses and interventions CIPESC. It is expected, with these interventions, facilitate the development of an instrument for good health management Jesuit Province of the other residences BRM.
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12

Keenen, Bridget. "The Role of SWI/SNF Chromatin Remodeling Complex in Melanoma." University of Toledo Health Science Campus / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=mco1271819328.

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13

RIGAMONTI, AURORA. "Functional characterization of SMARCA2 gene." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2016. http://hdl.handle.net/10281/130275.

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My PhD project is based on the characterization of the SMARCA2 gene. On one hand, I focused my attention on the role of SMARCA2 product, the protein brahma (BRM), in the regulation of alternative pre-mRNA splicing. On the other hand, I investigated the transcriptional regulation of SMARCA2 expression. My first project derived from a comparative evaluation and validation of microarray data from two mitochondrial stress models. The first model represented by an acute mitochondrial stress is constituted by human SH-SY5Y neuroblastoma cells treated with Paraquat (PQ), while the second model is a chronic model constituted from the same cell line stably overexpressing the Superoxide Dismutase 1 carrying the most common mutation found in familiar ALS (SOD1 G93A). The merge of these microarrays data showed that oxidative stress affects the choice of specific alternative last exons (ALEs) increasing the production of transcripts variants terminating at a more proximal ALE. Moreover, oxidative stress induces the transcriptional downregulation of the SMARCA2 gene product BRM, one of the two alternative ATPase subunits of the SWI/SNF complex. I found that in normal condition BRM is enriched on the proximal ALE. In addition, I observed the accumulation of BARD1, a protein that forms a functional heterodimer with BRCA1, which has E3 ubiquitin-ligase activity and interacts with the 50 kDa subunit of CstF inhibiting 3’ end processing. Consistent with these observations, I detected an ubiquitinated pool of CstF50 and showed that ubiquitination is mediated by BARD1/BRCA1. Taken together, these results suggested that the presence of BRM on the proximal exon leads to the BARD1/BRCA1-mediated ubiquitination of CstF50 and the inhibition of 3’ end processing at the proximal poly(A). This in turn allows transcription to proceed to the distal terminal exon. In the same microarray data used as a starting point for my first project we detected a shift in SMARCA2 expression towards shorter mRNA isoforms upon oxidative stress. Thus, my second project dealt with the characterization of these transcripts. Bioinformatic analysis revealed that the shorter mRNA variants are evolutionarily conserved and are most likely generated from an internal promoter. Interestingly, in zebrafish the short isoform is produced as an independent gene on the same chromosome of the long isoform but in its reverse strand. This peculiar genomic organization hints to a potentially relevant function for this alternative isoform of the BRM protein. Bioinformatic analyses revealed that the short isoform encode a protein that lacks the N-terminal, catalytic ATP-ase domain but shares the C-terminal region that contains a Bromodomain, a protein motif that is known to bind to acetylated histones. First, I identified the potential alternative promoter region using bioinformatic tools and cloned this region. Using a luciferase reporter system I demonstrated the existence of the alternative promoter. Next, I cloned the short, most conserved isoform and I tested it for interaction with known partners of the full-length BRM protein by Co-Immunoprecipitation (Co-IP). I discovered that BRM-s interacts with histone H3 but not with core component of the SWI/SNF complex. Considering that short isoform does not display an ATPase domain, the Co-IP suggests a possible “dominant negative” role for this protein. If short isoforms works as negative dominant of Brm, the ratio between long and short expressed proteins could become very important for BRM target genes in development and differentiation. In particular, this alteration of ratio could have a negative effect on the cells since several tumor cell lines show a very low level of the long protein. (i.e. human lung tumor cell lines).
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14

Coisy-Quivy, Marjorie. "Rôle de Brm dans le contrôle du cycle cellulaire et Étude de l'équilibre prolifération/différenciation des kératinocytes." Phd thesis, Université Montpellier II - Sciences et Techniques du Languedoc, 2004. http://tel.archives-ouvertes.fr/tel-00192360.

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Les principaux régulateurs de la prolifération cellulaire sont les Cdk (cyclin dependent kinase), dont l'activité dépend de leur association avec leurs partenaires, les cyclines. Le contrôle du niveau d'expression des cyclines représente le premier mécanisme par lequel l'activité des Cdk est régulée. Cette régulation est essentielle pour maintenir l'équilibre prolifération/différenciation de la peau. Cependant, les mécanismes mis en jeu restent peu connus.
Nous avons montré que Brm, protéine des complexes de remodelage de la chromatine SWI/SNF, est responsable de la répression de la cycline A par la mise en place ou le maintien de deux nucléosomes situés sur les sites d'initiation de la transcription. De plus, nous avons mis en évidence que l'absence de brm conduit à accélérer la progression des cellules dans le cycle cellulaire en jouant sur le déroulement de la phase S. Cependant, les cellules dépourvues de brm présentent également une mitose rallongée et des aberrations chromosomiques. Ceci pourrait être la conséquence de la dérégulation de trois oncogènes : c-myc, cycline A et cycline E et pourrait expliquer pourquoi brm est mutée dans de nombreux cancers.
Enfin, nous avons montré que l'entrée en différenciation des kératinocytes s'accompagne d'une forte expression de p21 qui entraîne un arrêt en G2/M en inhibant les complexes Cycline A/Cdk. Cependant, les kératinocytes en différenciation ne peuvent maintenir cet arrêt et entre dans un état G1 à 4N, caractérisé par une forte expression de la Cycline E et l'absence de Cyclines de G2/M.
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Coisy, Quivy Marjorie. "Rôle de Brm dans le contrôle du cycle cellulaire et étude de l'équilibre prolifération/différenciation des kératinocytes." Montpellier 2, 2004. http://www.theses.fr/2004MON20173.

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16

YOSHII, SAIJI, IZUMI NAKASHIMA, KOICHI ANDO, HIIZU AOKI, KATSUYA KATO, and MASAO IINUMA. "Purified Protein Derivative (PPD) Tuberculin as a Biological Response Modifier: I. Suppression of Tumor Markers by Intravenous Administration of PPD." Nagoya University School of Medicine, 1988. http://hdl.handle.net/2237/17502.

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17

Ortis, Fernanda. "Papel de BRG1 e Brm, reguladores globais de transcrição, na reversão fenotípica de células ST1 pela ação de glicocorticóides." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-26072007-053713/.

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Os hormônios glicocorticóides (GCs) têm sido amplamente empregados como agentes antiinflamatórios e anti-tumorais. Sua ação ocorre via receptores nucleares (GR) sendo dependente da remodelação da estrutura da cromatina. As proteínas Brm e BRG1, componentes essenciais de um complexo regulador global da transcrição (SWI/SNF), por remodelamento da cromatina, exercem um papel-chave na ação de GR. Para estudar o mecanismo de ação de GCs, foram utilizadas as linhagens celulares ST1 e P7, derivadas da linhagem celular C6, de glioma de rato. P7 é insensível ao tratamento com GC, enquanto ST1 apresenta reversão fenotípica tumoral→normal, gerando um bloqueio específico na fase G1. Um anti-soro policlonal específico para Brm e BRG1, foi gerado através da inoculaçâo de coelha com a proteína hBRG1 recombinante. Este antisoro foi utilizado para análisar os níveis destas proteínas nas duas linhagens celulares, sob ação de GC. Enquanto em ST1, Brm é induzida por GC, em células P7, o nível basal de Brm é relativamente alto, mantendo-se inalterado na presença de GC. A possíbilidade de existirem mutações no gene brm de células P7, foi investigada através de amplificação do DNA, por PCR, e seqüenciamento. A superexpressão de brm e BRG1 em células P7 mostrou que clones isolados apresentavam, de um modo geral, achatamento celular, diminuição da taxa de crescimento e da eficiência de plaqueamento em substrato sólido e semi-sólido. Alguns destes clones passaram a responder ao tratamento com GC, porém não tão drasticamente como as células ST1. Co-imunonoprecipitação mostrou algumas diferenças entre os complexos SWI/SNF de células ST1 e P7.
Glucocorticoid hormones (GCs) have been used as anti-inflammatory and anti-tumor agents, acting via nuclear receptors (GR) and being dependent on remodeling of the chromatin structure. As components of the global chromatin remodeling transcription complex (SWI/SNF), Brm and BRG-1 proteins play a key role in the action of GR. In order to study the mechanisms of action of GCs, we have been using the ST1 and P7 cell lines, derived from the C6, a rat glioma cell line. P7 is insensitive to the GC treatment, while ST1 displays a complete phenotypic reversion from tumoral to normal, including a G1-specific block in the cell cycle. A Brm and BRG1-specific polyclonal antiserum was generated, in rabbit, using recombinant hBRG1 protein as antigen. This antiserum was used to analyze the levels of Brm and BRG1 in these two cell lines, under GC treatment. While Brm is induced by GC, in ST1 cells, the basal level of Brm, in P7 cells, is relatively high, remaining unchanged under GC treatment. The possibility of brm mutations occurring in the P7 cells, was analyzed by DNA sequencing. Overexpression of brm and BRG1 in P7 cells led to morphological alterations (cell flattening) and decreased colony formation in agarose suspension and in solid substrate. Some of these clones became partially responsive to GC, when compared to the ST1 cell line. Co-immunoprecipitation assays revealed some differences in the SWI/SNF complex between ST1 and P7 cells.
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Boughzala, Oualid. "Contribution à la modélisation et à l'optimisation des bioréacteurs à membranes immergées (BRM) pour le traitement des eaux usées urbaines." Caen, 2015. http://www.theses.fr/2015CAEN2074.

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Le bioréacteur à membranes immergées (BRM) est une technologie performante pour le traitement des eaux usées urbaines. Elle améliore leur épuration et permet de délivrer un effluent exempt de matières en suspension. Toutefois, du fait de la rétention partielle de certains produits microbiens solubles (SMP), il est nécessaire de bien gérer le colmatage et d’optimiser l'utilisation des membranes. Cela nécessite une bonne connaissance et une modélisation fiable des processus microbiens impliqués. Les modèles ASM classiques montrent des écarts importants par rapport au fonctionnement réel des BRM. Le calibrage des paramètres des modèles existants s'avère complexe et délicat. Ce travail présente une synthèse et une analyse critique des principaux développements sur les SMP. Un modèle original basé sur l'ASM1 est alors proposé. Il décrit les processus biologiques associés aux SMP et prend en compte leur rétention partielle par les membranes. Ce nouveau modèle a nécessité la reformulation de certaines variables du ASM1 et l'introduction de nouvelles. Il a été testé et validé sur des données réelles de BRM, données issues de la littérature, couvrant différentes configurations (aérobie avec ou sans anoxie) et échelles (laboratoire, pilote et STEP). Le modèle intègre également les effets de la concentration en MES sur les constantes associées à l'utilisation de l'oxygène et plus généralement, les effets de la température. Enfin, il a été utilisé pour réaliser une étude sur l’optimisation du fonctionnement des BRM. Cette étude met en avant l'importance du choix des consignes en oxygène dissous, en relation avec la température, sur la qualité de traitement ciblée
Membrane bioreactor (MBR) is a powerful technology for wastewater treatment; it improves their purification and allows delivery a free suspended solids effluent. However, due to the partial retention of certain soluble microbial products (SMP), it is necessary to manage the fouling and optimize the use of membranes. This requires a good knowledge and reliable modeling of microbial processes involved. The use of conventional activated sludge models (ASM) shows significant deviations compared to the actual operation of MBR. The calibration of existing models parameters proves to be complex and delicate. This work presents a synthesis and a critical analysis of the principal developments on SMP. An original model based on the ASM1 is then proposed. It describes the biological processes associated to SMP and considers their partial retention by membranes. This new model has required the reformulation of certain variables of the ASM1 and the introduction of new ones. It was tested and validated on real data of BRM, data resulting from the literature, covering various configurations (aerobic with or without anoxic) and scales (laboratory, pilot, and MBR plant). The model also integrated the total suspended solids (TSS) effects on the oxygen uptake constants and more generally, the temperature effects. Finally, the model was used to optimize the BRM performance, highlighting the importance of choosing dissolved oxygen set-point, in relation with temperature, on targeted quality treatment
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19

Grani, Francesco. "The efficiency of xylem network in trees: a theoretical and experimental approach." Doctoral thesis, Università degli studi di Padova, 2011. http://hdl.handle.net/11577/3421650.

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In the trees, water moves through a negative pressure gradient established between roots and leaves, through a network of xylem cells whose length can reach the order of magnitude of 100 meters in the higher plants on the planet. The grandeur of the transport system involves the need for the plant to implement some tricks to cope with the increasing hydraulic resistance related with the dramatic lengthening of the water path throughout the ontogeny. That is to say that the increase in plant height is accompanied by a consequent increase of the total hydraulic resistance within the xylem conduits. The most effective solution to contain the increase of hydraulic resistance seems to be the tapering of the conduit elements. The introduction by WBE (West, Brown, Enquist 1997, 1999) model of the hypothesis of universality of the degree of xylem conduit tapering in vascular plants, leads to introduce a threshold value of the "optimal" degree of tapering such that the hydraulic resistance of a path is approximately constant regardless of its length (the conduit is always potentially capable of growing). It was therefore suggested that the nature of hydraulic limitations to growth in plant height may be the result of a sub-optimality of the degree of tapering caused by the physical inability to increase cell diameter at the base indefinitely. Alternatively, it is possible that a sub-optimality of the overall transportation system can occur at some point of the development in height (and therefore in length and volume of xylem conduits) due to the impossibility of maintaining a state of optimum equilibrium of the conduction system, designed as a transport network optimized (Banavar, Maritan, Rinaldo 1999) when the volume of service inside the network and the hydraulic resistance resulting in the displacement of this volume, are both minimized in a logical solution of a minimum equilibrium bound problem. One of the objectives of this work has been put together two of the main models proposed recently to the attention of the scientific community (the WBE model and the model BMR) and to collect them in the development of a new unique model, to try to answer the fundamental question implied in this research topic: "which factors causes the plants to stop growing in height?".
All'interno degli alberi, l'acqua si muove per mezzo di un gradiente negativo di pressione, che si instaura tra le radici e le foglie, attraverso una rete di cellule xilematiche la cui lunghezza può raggiungere l'ordine di grandezza di 100 metri nelle piante più alte del pianeta. Questa imponenza del sistema di trasporto comporta la necessità da parte della pianta di porre in atto degli stratagemmi per far fronte alla crescente resistenza idraulica che si sviluppa assieme al drastico allungamento di percorso idrico durante tutta l'ontogenesi. Vale a dire che l'aumento in altezza delle piante è accompagnato da un conseguente aumento di resistenza idraulica all'interno dello xilema. La più efficace delle soluzioni per contenere questo aumento di resistenza idraulica sembrerebbe essere la rastremazione degli elementi di conduzione. L'introduzione da parte del modello WBE (West, Brown, Enquist 1997, 1999) dell'ipotesi di universalità del grado di rastremazione dei condotti xilematici nelle piante vascolari, porta ad introdurre una soglia di rastremazione "ottimale" tale da rendere all'incirca costante la resistenza idraulica di un percorso a prescindere dalla sua lunghezza (potenzialmente sempre suscettibile di crescita). E' stato dunque ipotizzato che le limitazioni di natura idraulica alla crescita in altezza delle piante possano essere conseguenti all'insorgere di una sub-ottimalità del grado di rastremazione dei condotti proveniente dall'impossibilità fisica di aumentare indefinitamente il loro diametro alla base, od in alternativa che una sub-ottimalità generale del sistema di trasporto idraulico all'interno della pianta possa manifestarsi ad un certo punto dello sviluppo in altezza (e quindi in lunghezza ed in volume dei condotti xilematici) in conseguenza alla non possibilità di mantenimento di uno stato d'equilibrio ottimo del sistema di conduzione, pensato come una rete di trasporto ottimizzata (Banavar, Maritan, Rinaldo 1999) in cui il volume di servizio presente all'interno della rete e la resistenza idraulica conseguente allo spostamento di tale volume, siano entrambi minimizzati in una logica di soluzione d'equilibrio di minimo vincolato. Uno degli obiettivi di questo lavoro è stato mettere assieme due dei principali modelli recentemente proposti all'attenzione della comunità scientifica (il modello WBE ed il modello BMR) e di raccogliere nello sviluppo di un nuovo unico modello di scala le ipotesi e le intuizioni principali dei due, per cercare di dare una risposta alla domanda fondamentale sott'intesa in questo argomento di ricerca: "per l'insorgenza di quali fattori le piante smettono di crescere in altezza?".
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20

Le, Loarer François. "Dérégulation du complexe BAF dans les sarcomes épithélioïdes et leur variants génétiques." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10127.

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Les sarcomes épithélioides sont caractérisés dans 85% des cas par une perte d'expression nucléaire de la protéine SMARCB1, codée par un gène suppresseur de tumeurs situés en 22q11 impliqué dans la génèse des tumeurs rhabdoides malignes. L'exploration par BAC-FISH (Bacterial Artificial Chromosome- Fluorescence In Situ Hybridization) d'une série de 40 sarcomes épithélioides a permis d'établir que cette perte d'expression était secondaire dans 85% des cas à des délétions homozygotes et a mis en évidence le premier cas de sarcome épithélioide associé à une délétion germinale de SMARCB1, altération jusqu'alors uniquement identifiée dans les tumeurs rhabdoides malignes. Nous avons par la suite testé le gène suppresseur de tumeurs SMARCA4 comme gène candidat impliqué dans les sarcomes épithélioides SMARCB1-conservés à partir d'une série rétrospective de 16 cas. SMARCA4 code la sous-unité ATPase du complexe BAF dont SMARCB1 représente une sous unité. Ce screening initial a permis d'identifier 6 cas de sarcomes SMARCA4-inactivés dont la localisation était exclusivement thoracique et dont les caractéristiques clinique et anatomopathologique stéréotypées ont permis le recrutement prospectif et rétrospectif de nouveaux cas. L'étude par RNA-sequencing d'une fraction de notre cohorte (n=13/19) a confirmé leur homogénéité transcriptomique et souligné leur parenté avec les tumeurs rhabdoides SMARCB1 et SMARCA4 déficientes. L'absence de mutation germinale fréquente (n=1/11) a fait proposer le terme de sarcome thoracique SMARCA4-déficient (SMARCA4-DTS) en proscrivant l'utilisation du qualificatif « rhabdoide ». La parenté transcriptomique de ces tumeurs laisse entrevoir des vulnérabilités thérapeutiques communes qui restent à identifier
Epithelioid sarcomas (ES) display loss of SMARCB1 nuclear expression in 85% of cases. SMARCB1 is encoded by a tumor suppressor gene located in 22q11 which was first linked to cancer in malignant rhabdoid tumors. While investigating a series of 40 epithelioid sarcomas with BAC-FISH (Bacterial Artificial Chromosome-Fluorescence In Situ Hybridization), we demonstrated that SMARCB1 loss in ES occurred through genomic deletions in 85% of cases. We were also able to highlight the first case of ES associated with a heterozygous SMARCB1 deletion in the germ line, which feature was previously thought to be restricted to malignant rhadboid tumors (MRT). We subsequently investigated a series of 16 SMARCB1-retained ES to identify its underlying culprit gene with a focus on the candidate tumor suppressor gene SMARCA4. SMARCA4 encodes one of the ATPase subunit of BAF complexes. Interestingly, SMARCB1 is also a core submit of these complexes which regulate chromatin remodeling. We were able to identify a set of 6 cases displaying SMARCA4 inactivation with this discovery cohort. The review of medical records highlighted these cases had similar presentation : all tumors presented with large compressive and aggressive mediastinopulmonary masses. We further recruited 13 cases based on these characteristics including 5 prospective cases. The characterization of their transcriptomes by RNA-sequencing (n=13/19) confirmed their remarkable homogeneity, all our samples clustering together with MRT. However our variant diverge from malignant rhabdoid tumors as it lacks SMARCA4 alteration in the germline (n=0/11) and displays complex polyploidy genetic profiles. We therefore called this new tumor variant “SMARCA4-deficient thoracic sarcoma” (SMARCA4-DTS). The transcriptomic vicinity of SMARCA4-DTS and MRT let foresee they share common therapeutic vulnerabilities
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Robertson, John Graham Stuart. "Meeting optimally the environmental challenge : a methodology for the lead industry." Thesis, Brunel University, 2001. http://bura.brunel.ac.uk/handle/2438/5405.

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Does the lead industry have a future, in the face of the developing environmental challenge? This thesis addresses this question and concludes, it should have for the foreseeable future, providing it adopts the changes detailed. These changes are posited within a framework, which consists of a strategy, approaches and tools. The changes are both technical and philosophical. They are technical, in the sense that the tools and approaches provide practical means whereby the environmental `risks' may be identified, assessed and managed. They are philosophical, because they set out and identify the features of a new conceptual paradigm, whose basis is in the concept of the `risk society'. The paradigm is significantly more holistic, multi-dimensional, inherently flexible, and is intended to be reflexive. Adoption of the elements of the framework, will facilitate a more effective establishment, and management of environmental `risk' credentials, which will help encourage better environmental decision making. Hence, it will facilitate, the balancing of resource consumption and environmental impact costs, versus social and economic benefits, in an improved manner. The modelling approaches, and selected inventory and environmental impact assessment tools, enclosed within this thesis, have been designed to facilitate the development of, and to function within, the new paradigm. These have been developed for BRM and MIM case studies, and function at the site-specific and the cradle-to-gate scales. The former consider the company site of Britannia Refined Metals (BRM) Ltd., where refining to produce primary and secondary refined lead products takes place, whilst the latter consider the life-cycle of the refined primary lead products of MIM Ltd. The modelling approaches have also been designed so, that they may be re-aggregated into models able to operate at many different scales, as required. The framework, and its elements, are applicable for all industries facing similar challenges.
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Castañeda, Okamura Carlos Alejandro, Delgado Rocío Mejía, Bazán Guillermo Adrian Otoya, and Ramírez Marco Antonio Pizarro. "Diseño de una Metodología para la Dirección de Proyectos Basada en la Guía del PMBOK® 6ta. Edición y la Guía Práctica de Gestión de Realización de Beneficios (BRM) en la Empresa CIME Ingenieros S.R.L." Master's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/652952.

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En la dirección de proyectos actual, se ha fortalecido la tendencia de una gestión de realización de beneficios, los cuales están directamente relacionados con los objetivos organizacionales de la empresa que desea materializar estos beneficios. Este proceso plantea, al inicio de los proyectos, una identificación de beneficios, para luego asegurar durante el desarrollo del proyecto que estos se realicen y se sostengan cuando el proyecto culmine. Es por ello, que ante la evolución vertiginosa de la competencia en el sector servicios, la empresa CIME busca generar valor en la entrega de trabajos de construcción y mantenimiento industrial en refinerías. Para esto, es necesario lograr que sus proyectos se entreguen de forma exitosa a sus clientes y que estos logren materializar los beneficios propuestos para la compañía. En el presente trabajo de investigación se propone desarrollar una metodología para la dirección de proyectos de la empresa CIME basada en los lineamientos de la Guía de los Fundamentos del PMBOK® 6ª. Ed. y en la Guía Práctica de Realización de Beneficios, ambas publicaciones del Project Management Institute (PMI). Esta metodología buscará cerrar la brecha existente entre la situación actual de la empresa y la situación deseada en relación a la Dirección de Proyectos y la Gestión de Realización de Beneficios desde el origen del proyecto, buscando formalizar sus procesos y estandarizar las actividades promoviendo una gestión óptima de los proyectos. Además, la metodología velará por la búsqueda de una alineación estratégica de sus proyectos a los objetivos organizacionales. En el desarrollo de este trabajo de investigación se diseñarán procesos que abarcarán desde la evaluación de ejecución del proyecto hasta el logro de los beneficios que contribuirán a la implementación de la estrategia de CIME. Para cada uno se especifican sus entradas, herramientas y técnicas, salidas, plantillas y subprocesos de fácil uso del Director del Proyecto y su equipo.
In the current project management, the trend of managing the realization of benefits has been strengthened; those benefits are directly related to the organizational objectives of the company that wishes to materialize them. This process proposes, at the beginning of the projects, to identify the benefits, and then guarantee, during the development of the project, that these are realized and sustained when the project ends. For this reason, given the dizzying evolution of competition in the service sector, the CIME Company seeks to generate value in the delivery of construction and industrial maintenance work in refineries. For this, it is necessary to ensure that their projects are successfully delivered to their clients and that they achieve the proposed benefits for the company. In this research work it is proposed to develop a methodology for project management of the Company CIME based on the guidelines of the PMBOK® Guide 6th. Ed. and in the “Benefits Realization Management: A practice guide”, both publications of the Project Management Institute (PMI). This methodology will seek to close the gap between the current situation of the company and the desired situation in relation to Project Management and Benefits Realization Management from the beginning of the project, seeking to formalize its processes and standardize activities promoting optimal management of projects. In addition, the methodology will ensure the search for a strategic alignment between its projects and the organizational objectives. In the development of this research work, processes will be designed, ranging from the project evaluation to the achievement of project benefits and contribution to CIME’s strategic implementation; for each of them, its inputs, tools and techniques, outputs and threads are specified in a user friendly way for the project manager and his team.
Trabajo de investigación
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23

Benoni, Daniel. "Business Activity Monitoring v řešení Business Intelligence." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-15593.

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Business Activity Monitoring (BAM) is an acronym of Gartner Inc. to describe systems that are intended to provide "Real-time access to critical business performance indicators to improve the speed and efficiency of business operations. BAM systems help enterprises improve their operational efficiency and increase the ability of understanding and responding to events that have a significant impact on their business processes. Despite the fact that most businesses today are in urgent need to improve their operating performance, BAM systems as a solution seams to don't approach. The reality is that many software vendors supplied new BAM systems solutions by simply adding new features to existing products. In addition, there are no formal standards to define which specific features of the BAM system should contain. Another problem is the lack of theoretical models to support comparative analysis between the different systems of BAM. The aim of my thesis is to contribute to the improvement of the existing theoretical basis for the use of Business Activities Monitoring (BAM) as part of BI solutions, by providing an understanding of the relationship between the needs of decision support systems in real time and current applications of systems BAM. This work provides evidence that the relationship between the Real-time Business Intelligence needs of enterprises and BAM solution is determined by the need to ensure that the BAM system deliver current Real-time information to enable BAM users, who are often operating managers directly responsible for business processes, effectively respond to referred alert, supplied by the BAM system. To increase users' ability to effectively respond to events generated by the BAM system depends primarily on two basic operational issues. First, it is necessary to ensure adequate response for BAM users, to ensure necessary actions associated with the event. Second, BAM user must be able to understand the nature of the problem associated with the event, to initiate the proper steps to resolve the problem. Here it shows that, apart from insufficient knowledge of the nature of problems, BAM system needs, beside generation alerts in very low latency, also add context to these alerts, to provide enough information for BAM users to understand the nature of the problem associated with the event.
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AbuElmaati, Ahmed, and Trym Sørensen Bernløv. "Effectiveness of Benefits Management Frameworks : in monitoring and controlling public sectors projects in the United Kingdom." Thesis, Umeå universitet, Företagsekonomi, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-183066.

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Purpose – This research aims to explore the effectiveness of utilising Benefits Realisation Management (BRM) as part of comprehensive success measures, emphasising the stage in-between appraisal and evaluation of projects in the UK public sector. Design/methodology/approach – The study is constructed as a qualitative case study. Semi-structured interviews are used as part of the inductive, exploratory approach to achieve the study's objectives. It employs an approach based on grounded theory for its analysis. Findings – This paper suggests that Benefits Realisation Management is not used effectively in the UK public sector during projects lifetime to control and monitor projects and ensure their success. The current reviews of projects and programmes, through their execution, may not be sufficient. Research limitations/implications – This study offers contributions to the project success literature and benefits management literature by adding empirically supported insights about BM utilisation during project reviews. The research may be limited primarily by the research method – predominantly the snow-balling data collection. The assumptions made about the UK public sector may limit the broader generalisation of the findings. Practical implications – This research may be used to advise the practising managers of the need to maintain benefits orientation after appraisal throughout a project's lifetime and after delivery. Project governance structures are advised to update and improve their current project review practices. The study additionally identifies possible obstacles to the process and biases. Originality/value – This paper attempts to fill a literature gap by providing empirical results that explore the success definition and measures and the effectiveness of BRM during project execution and gate reviews. Keywords: Benefits Management; Project Success; Project Performance; Performance Measurement; Public Sector. Paper type: Research Thesis
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Martins, Ladigenia Tereza. "Bom e bem e suas multifunções na fala da região sul do Brasil." Florianópolis, SC, 2003. http://repositorio.ufsc.br/xmlui/handle/123456789/84608.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Linguística.
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Particularmente centrados nos pressupostos teóricos do Funcionalismo Lingüístico e da Teoria da Variação, procuramos nesta pesquisa descrever o comportamento discursivo das palavras bom e bem na fala de informantes da região sul do Brasil. Para isso, utilizamos dados extraídos de uma amostra composta por 288 entrevistas, pertencente ao Banco de Dados do VARSUL (Variação Lingüística Urbana no Sul do Brasil). A partir de uma análise qualitativa, apresentamos as atuações de bom e bem nos diversos contextos discursivos e caracterizamos suas respectivas funções. Ligados à propriedade comum de chamada de atenção para a informação, tratamos as lexias como variantes de uma mesma variável lingüística e, conseqüentemente, dispensamos às formas uma análise quantitativa.
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Lehmkuhl-Dakhwe, K. Virginia. "Regulation of p53, p21, ARF, BIM, and BAX by the Transcription Factor Trip-Br1." Ohio University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1194549826.

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Silva, Cornejo Ignacio Agustín. "Modelamiento de sistema de monitoreo de rendimiento de servicios sobre arquitectura SOA." Tesis, Universidad de Chile, 2007. http://repositorio.uchile.cl/handle/2250/104774.

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El principal objetivo de este trabajo de memoria es definir, especificar requerimientos y modelar todos los elementos, componentes, relaciones y dependencias que dan forma a una arquitectura SOA, para la capa VAS de una empresa de telefonía móvil. Sobre esta arquitectura, se definirá y planteará la estructura y organización necesaria para la implantación de un sistema BAM, de manera de cubrir las necesidades técnicas y de negocio que la arquitectura SOA no logra cubrir.
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Reblin, Lisa, and Saman Sharif. "Effektivisering av ritningsredovisning av broar med hjälp av BIM : En fallstudie där en bro modelleras i Tekla Structures." Thesis, KTH, Byggteknik och design, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-192074.

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Mossberg, Magnus. "Mental kompetens : Tänk bra – må bra – prestera bra." Thesis, Halmstad University, School of Teacher Education (LUT), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-2157.

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SYFTE: Jag har i mitt yrke erfarit att många elever upplever skolan som stressande. Studier

stöder denna iakttagelse och visar att för många tonåringar är skolan den i särklass största

stressfaktorn. Vidare ökar stressrelaterade sjukdomar bland vuxna kraftigt. Detta gav mig en

ide att inom skolans ram försöka agera preventivt och inspirerad av coachning och kognitiv

beteendeterapi satte jag samman en kurs. Här undersökte jag huruvida träning i mental

kompetens; kunskap om kroppens känslosystem, språk för känslor, stresshantering och

problemlösningsstrategier, skulle kunna ge elever större känsla av beredskap för att hantera

livet i ett modern komplext samhälle och därmed en högre livskvalitet. METOD: Innan och

efter kursen utvärderades elevernas förmåga att hantera för dem stressiga situationer samt

aktionsberedskap i situationer som kräver handling. Under kursens gång gjordes kontinuerliga

utvärderingar och dessutom genomfördes en muntlig och skriftlig utvärdering vid kursens

slut. Vidare förde jag en personlig loggbok där för mig viktiga iakttagelser noterades.

RESULTAT: Eleverna visade avsevärd förbättring av de undersökta kompetenserna.

Dessutom upplevde så gott som samtliga att kursen behandlat för dem viktiga saker och att de

kände sig psykiskt starkare av kursen. SLUTSATS: Undersökningen visar att det på kort tid

går att avsevärt höja elevers förmågor inom mental kompetens. Skolan bör undersöka

huruvida undervisning i mental kompetens bör ingå i den ordinarie undervisningen.

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Boman, Johanna, and Josephine Ekhager. "Hur bra är bra tills bra blir dåligt?" Thesis, Högskolan i Gävle, Avdelningen för ekonomi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-34173.

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Akbarieh, Arghavan. "Developing a systematic approach to investigate interoperability issues between Building Information Modeling (BIM) tools and Building Energy Modeling (BEM) tools." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/15673/.

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Integrated building design necessitates the Architecture-Engineering-Construction-Owner-Operator (AECOO) Industry’s participants to collaborate efficiently with each other through the different phases of a building. Nevertheless, to reduce the energy consumption and CO2 emissions of a building, the emphasis is on the early design phases, since if accurate energy calculations and strategies are developed in an early design stage, the sustainable footprint of the building will be significantly reduced. That said, Building Information Modelling (BIM) promotes collaboration among the stakeholders by allowing them to design and store and access the data related to a project into one building information model. Furthermore, this model can be used for energy analysis through Building Energy Modelling (BEM) tools in the early design stages of the project, and through the whole life-cycle. For this, BIM and BEM tools must be able to communicate and exchange information with one another, seamlessly. This means that these tools should be interoperable. However, currently, there are some issues in the BIM to BEM exchange process, which obliges the user to check for the interoperability issues and fix them manually. Therefore, as a result of these interoperability issues, the BIM to BEM process in not automated, and creating an accurate BIM-based BEM is quite time-consuming, laborious and prone to human-made errors. Hence, this thesis aims to systematically investigate the interoperability issues and the state of automated data exchange between BIM and BEM tools, based on the Industry Foundation Class (IFC) exchange data schema. For this, Revit and IDA-ICE are used as BIM, and BEM tools, respectively. The outcome is the presentation of a set of interoperability issues that were found based on the investigation of 19 case studies, with some suggestions for Revit and IDA-ICE developers and future researchers in the end.
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Gabriella, Öström, and Högström Lina. "Symtomförekomst och noceboeffekter hos individer med byggnadsrelaterad ohälsa." Thesis, Umeå universitet, Institutionen för psykologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-149104.

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Byggnadsrelaterad ohälsa (BRO) är en av flera miljökänsligheter. De två konstrukten modern hälsooro (MHO) och somatosensorisk förstärkning (SSA) har båda visat sig kopplade till nocebo och de uppvisas ofta hos personer med miljökänsligheter. Det första syftet med uppsatsen var att öka förståelsen för vilka symtom som kännetecknar BRO, vilket undersöktes via 20 items utvalda från The Idiopathic Enviromental Intolerance Symtom Inventory (IEISI) vilka överensstämmer med WHOs lista över BRO-symtom. Det andra syftet var att öka kunskapen om vilken roll nocebo har i BRO, vilket undersöktes via Modern Health Worries (MHWS) och Somatosensory Amplification Scale (SSAS). Data inhämtades från en pågående studie vid Umeå Universitet. Urvalsgruppen utgjordes av 79 individer som uppgett att de upplevde BRO-symtom varje vecka. Data analyserades via korrelationsanalyser. Gruppen uppvisade variation i vilka och hur många symtom individerna rapporterade. Resultatet från korrelationsanalyserna visade sammantaget på att nocebo inte hade en betydande roll i rapporterandet av BRO-symtom i urvalsgruppen. Studien visade att gruppen med BROpatienter varken oroade sig mer än norm eller var särskilt känsliga för sensoriska intryck.
Building Related Illness (BRI) is one of several environmental sensitivities. The two constructs Modern Health Worries (MHW) and Somatosensory Amplification (SSA) have both been shown to be linked to nocebo and are often reported by people with environmental sensitivities. The first purpose of this paper was to increase the understanding of symptoms that characterize BRI, which was investigated via 20 items selected from The Idiopathic Enviromental Intolerance Symptom Inventory (IEISI) that complies with WHO's list of BRI symptoms. The second purpose was to increase knowledge about the role of nocebo in BRI, which was investigated via Modern Health Worries Scale (MHWS) and Somatosensory Amplification Scale (SSAS). Data was obtained from an ongoing study at Umeå University. The sample consisted of 79 individuals who reported that they experienced BRI symptoms each week. Data was analyzed via correlation analyzes. The group showed variability concerning which and how many symptoms the individuals reported. The results from the correlation analyzes showed that nocebo did not play a significant role in the reporting of BRI symptoms in the selection group. The study showed that the group of BRI patients neither worry more than the norm nor was particularly sensitive to sensory impressions.
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Jahn, Alexandre. "Estilo de vida e percepção de bem-estar em trabalhadores da Associação Franciscana de Ensino Senhor Bom Jesus em Santa Catarina." reponame:Repositório Institucional da UFSC, 2012. http://repositorio.ufsc.br/xmlui/handle/123456789/93217.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2009
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O objetivo do estudo foi analisar o estilo de vida e os indicadores de saúde de funcionários da Associação Franciscana de Ensino Senhor Bom Jesus, das cidades de Blumenau, Florianópolis e Jaraguá do Sul, do Estado de Santa Catarina. Os dados foram coletados com a aplicação de questionário já validado e aplicado com trabalhadores da indústria com as devidas adaptações para a pesquisa em escolas. Os questionários (n=327) foram distribuídos a todos os professores e funcionários das três unidades de ensino, obtendo-se um retorno de 130 questionários respondidos de forma completa. Foi utilizado o programa SPSS for Windows (versão 16.0) para análise dos dados. Quanto às características demográficas obtiveram-se os seguintes resultados: a maioria possui menos de 40 anos de idade (67,7%); são casados (61,2%); possuem pós-graduação (57,5%); recebem acima de cinco salários mínimos (60,6%) e tem um ou mais filhos (60%). Relativamente à autopercepção de saúde, somente 19,4% entre os homens e 16% entre as mulheres tem percepção negativa com relação ao seu atual estado de saúde. Mais da metade dos homens (52,8%) e das mulheres (60,9%) tem percepção positiva com relação ao bem-estar no lazer. Na percepção de bem-estar no lar os resultados mostram que 91,7% dos homens e 87% das mulheres se sentem bem ou muito bem. No item relacionado ao bem-estar no trabalho, 91,7% dos homens e 87% das mulheres tem percepção positiva. Como fatores relevantes para o bom desempenho no seu trabalho, 40,5% destacam as condições físicas e materiais adequados; 30,2% respeito por parte do cliente (alunos e pais); e 23,3% reconhecimento dos superiores. Quanto à prática de atividade física, mais de 80% dos sujeitos deslocam-se de maneira passiva para os colégios. Em geral, 76,4% realizam atividades domésticas mais pesadas em pelo menos um dia da semana. A atividade física no lazer é um hábito mais significativo entre os homens, com participação de 83,3% dos entrevistados contra 53,8% das mulheres. Comparando com pessoas de mesma idade e sexo a sua condição física, 38,9% dos homens se vêem em melhor condição e 46,2% das mulheres se vêem em condição semelhante. Quanto ao fumo, 94,5% dos entrevistados afirma não fumar e 79,8% não fazem uso de bebida alcoólica. Quanto ao IMC observou-se que 52,8% dos homens apresentam-se com excesso de peso, enquanto apenas 20,9% das mulheres encontram-se nesta condição. Observando a frequência de almoço fora de casa, 42% dos entrevistados almoçam fora todos os dias de trabalho. Já a refeição matinal é feita em número maior ou igual a cinco dias semanais por 73% dos trabalhadores. Em geral, observa-se que os sujeitos têm uma percepção bastante positiva de bem-estar no trabalho, no lar e, um pouco menos positiva, no lazer. Os indicadores do estilo de vida também se apresentam, em geral, como positivos, com os homens apresentando mais comportamentos negativos que as mulheres.
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Pedreira, Vanda do Amaral V. "Espectroscopia Raman em compostos KBr-Br2, KI-Br2 e do HOPG-Br2." [s.n.], 1996. http://repositorio.unicamp.br/jspui/handle/REPOSIP/277833.

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Orientador: Gilberto M. Gualberto
Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Fisica Gleb Wataghin
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Resumo: Os cristais iônicos KBr e KI não apresentam atividade Raman. Espectros Raman destes cristais, após imersão em bromo líquido, exibiram linhas com freqüências identificadas como sendo devida aos compostos KBr3 e IBr, ao Br2 e às formas alotrópicas 79Br -79Br. 79Br -81Br e 81Br -81Br e aos íons Br3- e Br5-. -Espectros Raman do grafite pirolítico altamente orientado (HOPG) intercalados com Br2 foram estudados. O estágio encontrado foi n=2, evidenciado pelo pico intenso em w = 244 cm-1 e pelos seus harmônicos 2w0 ,3w0 ,4w0 ... . Estruturas menores foram observadas na região espectral dominada pelo bromo sólido
Abstract: The ionics crystals KBr and KI do not present Raman activity. Raman spectra of these crystals after immersing in liquid bromine exhibits lines with frequencies identified as been due to the compounds KBr3 and IBr, to the alotrophics forms 79Br - 79Br, 79Br- 81Br and 81Br - 81Br and to the ions Br3- and Br5-. -Raman spectra of highly oriented pyrolitic graphite (HOPG) intercalated with Br2 were also investigated. The stage number found was n=2, evidenced by the intense peak in w0 = 244 cm-1 and by its harmonics 2w0, 3w0, ... . Minor structures were also observed in the spectral region dominated by the solid bromine
Mestrado
Física
Mestre em Física
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Dallilo, Felipe Diniz. "Uma abordagem multinível para a obtenção de alinhamento estratégico no gerenciamento de processos de negócio." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/55/55134/tde-08072014-100834/.

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Teoricamente, o Alinhamento Estratégico pode ser obtido com um bom Gerenciamento de Processos de Negócio (BPM na sigla em inglês), porém a relação entre esses temas é, na maioria das vezes, assumida implicitamente e pouco elaborada, tornando-se difícil a visualização e vínculo entre as estratégias e os modelos de processos detalhados, sendo necessário empreender pesquisas na direção de uma união efetiva dos dois temas. O presente trabalho desenvolveu um metamodelo multinível, para ligar os objetivos estratégicos com os processos de negócio da organização através da modelagem de processos de negócio. O trabalho conceitual foi acrescido por uma ferramenta de suporte à modelagem que permite a geração de modelos com base no metamodelo multinível e também a representação dos modelos em diferentes formas de abstração. A abordagem foi aplicada em uma grande multinacional e posteriormente foi conduzida uma avaliação experimental no qual foram realizadas entrevistas com funcionários de diferentes níveis hierárquicos para validar a eficiência e eficácia do trabalho desenvolvido. Como resultado foi possível constatar não apenas a efetividade em alcançar os objetivos propostos como também a facilidade na utilização e compreensão da abordagem em níveis devido a simplicidade na representação dos elementos e seus possíveis relacionamentos
Theoretically, the Strategic Alignment can be accomplished with a good Business Process Management, but the relationship between these themes is, most often, implicitly assumed and little developed, making it difficult to visualize and link between the strategies and the models of detailed processes, being necessary to undertake research towards an effective union of the two themes. This study developed a multilevel metamodel for connecting strategic objectives with organizational business processes through modeling of business processes. The conceptual work was increased by a support tool for modeling that allows the generation of models based on multilevel metamodel and also the representation of models in different forms of abstraction. The approach was applied in a large multinational and was subsequently conducted an experimental evaluation in which interviews with employees from different hierarchical levels were performed to validate the efficiency and effectiveness of their work. As a result it was possible to not only the effectiveness in achieving the proposed objectives as well as the ease of use and understanding of the tiered approach because of the simplicity in the representation of the elements and their possible relationships
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Castro, Allende Marcos. "Skola i förändring : Bra betyg = Bra demokrat?" Thesis, Linnéuniversitetet, Institutionen för statsvetenskap (ST), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-27302.

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Title: School in Change : Good Grades = Good Democrat?   Level: Final assignment for Bachelor Degree in Political Science   Author: Marcos Castro Allende   Supervisor: Per Strömblad   Date: 2013 – May   Aim: The background to this study is a book published by Staffan. I Lindberg & Richard Svensson where they presented a hypothesis that the decline in trusting democracy within Swedish youth is a result of the deregulation of the education in Sweden. The aim of this study is to test this hypothesis and see if the declinne in democracy can be seen already before graduating from elementary school.   Method: The method used in this study consist of a survey distributed to students at two elementary schools that differentiates in question of grades and social status. By comparing and analyzing the results of this survey with the claims of the hypothesis, former studies and Lipsets theory of the working-class authoritarism a conclusion is made of the hypothesis credibility.   Result & Conclusions: The results showed that there may be a a difference trusting democracy between students with higher grades and those with lower grades. The result also showed that there is a difference in trusting politicans, a claim that was of great importance for the hypothesis. Therefore further research must be done to address this anti-hypothesis factor.   Contribution of the thesis: This study can, inspite its minor scale, contribute with a little more specific material for proving Lindberg & Svenssons hypothesis and also be used as a help to further research in the issues between school quality and trust in democracy.
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Edwards, Mannheimer Rebecca. "Mammabarnanstalt : Barn i fängelse - bra för barnet, bra för mamman, bra för samhället." Thesis, KTH, Arkitektur, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-34754.

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Synen på vad som är bäst för barnet då modern sitter på anstalt har förändrats. Det har visat sig att det bästa för barnet i många fall är att stanna hos sin moder trots fängelsevistelse, snarare än att separeras och placeras i fosterhem vilket tidigare varit den rådande uppfattningen. Mitt förslag är ett ställningstagande i en nu rådande het debatt.
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Lindén, Anna, and Peter Dehlin. "BIM i planeringsarbetet : Effective planning by using BIM." Thesis, Tekniska Högskolan, Högskolan i Jönköping, JTH, Byggnadsteknik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-19131.

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Abstract The importance of good construction planning affects the final costs of the production and the timing of the project. Planning for building projects has been studied with the aim of identifying how three week planning appears in the construction industry today. A case study has been conducted in Navisworks Simulate to assess whether the software is suitable to connect the task schedule with the BIM model to create a 4D model. 4D models are used for performing 4D construction simulation to visualize the project. In order to use the benefits of the model, investment in equipment and software is required. This means higher costs for the companies. Therefore inexpensive software is needed so that it will be profitable to use 4D models even in the production of small projects. The survey which aims to identify planning in the construction industry shows that planning varies between the different sectors, but also that planning technique depends on the knowledge of those who actually carry out the planning. The conclusion is that education in planning techniques and computer aided planning tools is needed to implement BIM in the planning process. With a detailed schedule and a BIM model which is adjusted to the construction of the building, Navisworks Simulate is a suitable program to use in the creation of Building Information Models. When using Navisworks Simulate to create a 4D model, the natural choice would be Navisworks Freedom software for visualization of the project in the production. This is because the Navisworks creates its own file format, which can only be opened in software created by Autodesk. This study was aimed to improve three week planning and increase the use of assimilating feedback by using BIM in the construction industry. The conclusion is that the choice of software for the creation of a 4D model affects the application that later can be used for visualization.
Sammanfattning Vikten av god produktionsplanering ligger till grund för dels den ekonomiska produktionskostnaden, dels tidsaspekten i projektet. Som bakgrund till rapporten har planering i byggproduktionen studerats med syftet att kartlägga hur treveckorsplaneringen ser ut inom bygg- och anläggningsbranschen i dagsläget. En fallstudie har genomförts i Navisworks Simulate för att undersöka om programvaran lämpar sig att sammankoppla treveckorsplanering med BIM-modell för att skapa en 4D-modell. 4D-modellen används för att på ett tydligt vis visualisera arbetet i projektet. För att utnyttja modellen krävs investeringar i utrustning och programvaror vilket innebär dyra kostnader för företagen. För visualisering av projektet eftersträvas därför en programvara till låg kostnad så att det ska bli lönsamt att använda 4D-modellen i produktionen även på mindre projekt. Den utredning som genomförts med syftet att kartlägga planeringsarbetet inom bygg- och anläggningsbranschen visar att planeringsarbetet varierar dels mellan bygg- och anläggningsprojekt men även att planeringsteknik beror på kunskapssnivå hos den som ska genomföra planeringsarbetet. Slutsatsen är att utbildning i planeringsteknik och datorstödda planeringsverktyg behövs för att kunna implementera BIM i planeringsarbetet. Med en detaljerad tidsplanering och produktionsanpassad projektering är Navisworks Simulate ett utmärkt program att använda vid skapandet av BIM-modeller. Vid användandet av Navisworks Simulate för skapande av 4D-modellen är Navisworks Freedom det naturliga valet av program för visualisering ute på arbetsplatsen i produktionen. Detta beror på att Navisworks skapar sitt eget filformat, vilket endast går att öppna i programvaror från Autodesk. Slutsatsen blir att valet av programvara för skapandet av en 4D-modell påverkar vilka program som senare kan användas för visualisering. Examensrapporten syftar till att förbättra treveckorsplaneringen, samt att öka utnyttjandet av erfarenhetsåterföringen inom produktionen genom användande av CAD-samordning och BIM.
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AL-Hindi, Rafah, and Yousef Yousef. "BIM Byggnadsinformationsmodellering BIM-användning hos de olika aktörerna." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-61162.

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Clarus arkitekter som projekteringsföretag får ofta beställningar från entreprenörer och beställare där de efterfrågar en BIM-modell. I de flesta fallen så används inte BIM modellen helt utan man tar fram 3D-ritningar eller 2D-ritningar. Då ställs frågan “Har beställaren/entreprenören rätt uppfattning om vad BIM är?” Olika aktörer har olika riktlinjer och krav som projektören ska följa. Frågan som arbetet kommer svara på är “hur ska konsulten göra för att på bästa sätt kunna erbjuda rätt tjänst samt mot vilka mål ska konsulten jobba.” Syftet med den här fallstudien är att ta reda på hur BIM användningen skulle kunna underlätta arbetet samt kommunikationen mellan de olika aktörerna som är inblandade i ett byggprojekt. Att undersöka hur kompetensnivån ligger till hos Beställare, Entreprenör och projektörer/arkitekter och svara på frågan “Vad ligger bakom kompetensskillnaden som finns?” Arbetet inleddes med litteraturstudier för insamling och sammanställning av information. Frågor kommer att ställas upp för att senare kunna användas under intervjuerna med olika personer från olika företag. Intervjuerna kommer att ske med bland annat med individer från konsult-, entreprenör- och beställare företag. Intresset att använda BIM är stort i branschen men tyvärr så finns det stor kompetensbrist. Beställare och entreprenörer har planer att börja använda sig av BIM mer vilket kommer att ske de kommande åren, men i nuläget så vill man inte ta nya risker och föredrar att använda sig av traditionella metoder som är mer säkra. För att man skulle kunna tillämpa BIM mer i byggbranschen så behövs det mer kunskap.
Clarus Arkitekter as design companies often receive orders from contractors and clients asking for a BIM model. In most cases, the BIM model is not fully used, but 3D drawings or 2D drawings are available. Then asks the question "Does the client / contractor have the correct understanding of what BIM is?" Different players have different guidelines and requirements that the projector should follow, which can be perceived as defective by the projector just to know what is demanded from each client. The question the thesis will answer is "How should the consultant do the best to offer the right service and what goals the consultant will do. The purpose of this master thesis is to find out how BIM usage could facilitate the work as well as the communication between the various actors who is involved in a construction project. To investigate how the level of competence lies with the Client, Entrepreneur and Projectors / Architects and answerthe question "what is behind the skill difference that exists?". The work began with literature studies for the collection and compilation of information. Questions will be set up to later use them during interviews with different people from different companies. The interviews will take place with individuals from consultancy, contractor and client company. The interest in using BIM is high in the industry, but unfortunately there is a great deal of skills shortage. Customers and entrepreneurs plan to start using BIM more, which will happen in the coming years, but now, they do not want to take new risks and prefer to use traditional methods that are more secure. To be able to apply BIM more in the construction industry, more knowledge is needed.
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Wikström, David, and Tobias Karlemi. "Varför BIM?" Thesis, Jönköping University, JTH, Civil Engineering, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-1370.

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Is the new technology always the best? This final project tries to determine if BIM is the melody of today, or if traditional 2D drawing is recommended. Perhaps a compromise is necessary, utilizing both methods.

In order to answer this question, different views from the industry have been retrieved through reports, producers of software and users. The approach has consisted in building a 3D model of the school Råslättsskolan, house 01, along with interviews with people involved in the building process.

When working in 2D it is hard to include the third dimension, mistakes are done and collisions happen that must be corrected, in most cases at the construction site. BIM is an incredible help since the model allows you to detect collisions and correct them. Another time when models are preferred is when you need production plans, for example, different steel details that will be joined together at the work shop before shipping to the construction site.

Skanska and NCC, in densely developed urban areas, already require BIM today, something that most likely will be customary within the nearest future. It is not hard to understand that more and more clients require BIM when you realize its advantages. With the correct method, these 3D models can minimize risks of errors, optimize the production and save money.When it comes to introducing BIM today at BGK the students can’t do anything but make a recommendation. The improved quality, the future prospect and that the advantages of BIM is not depending by project size will make it attractive for BGK to begin a transition already today. BIM is the melody of the future, not the only song being sung, but clearly the strongest one.

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Knutsen, Erik. "BIM-Koordinering." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for bygg, anlegg og transport, 2014. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-25557.

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BIM handler om mer enn kun 3D-modeller. Det handler også om mennesker og prosesser. Innføring av BIM endrer prosessene og krever nye kunnskaper av menneskene i prosjektorganisasjonen. Implementering av BIM har ført til nye begreper som BIM-koordinering og BIM-koordinator. Formålet med denne oppgaven er å gå dypere inn i hva BIM-koordinering som funksjon er og hvordan BIM-koordinering håndteres på best mulig måte i prosjekter, samt om det er en sammenheng mellom hvordan BIM-koordinering håndteres og type prosjekt. Oppgaven har sett på hva BIM-koordinering er i administrerende prosesser, hvor BIM-koordinering handler om å koordinere og lage en BIM-plan som definerer målet med BIM, strukturen til modellen og hvem som skal gjøre hva og når. I prosjekteringsprosessen handler det om å koordinere de prosjekterende til å levere etter- og følge BIM-planen med riktig struktur og til riktig tid. Det handler også om å sammenstille modeller, kontrollere dem og koordinere og løse konflikter fra kollisjonskontroller. Siste prosess oppgaven har tatt for seg er produksjonsprosessen. I den prosessen handler BIM-koordinering i stor gran om å tilrettelegge for de utførende slik at de kan ta i bruk BIM. BIM-modellene må også her sammenstiller og kontrolleres, samt koordinering slik at as built modellen blir riktig. På hvilken BIM-koordinering bør håndteres kan grovt sett deles inn i to metoder. Enten opprette en egendefinert BIM-koordinatorrolle til å ivareta BIM-koordinering eller at funksjonen fordeles på de eksisterende rollene hvor prosjektorganisasjonen kan få støtte av en sentral BIM-koordinator i kortere perioder. Oppgaven ser det som mest hensiktsmessig at prosjekteringslederen har hovedansvaret med støtte fra andre roller og en sentral BIM-koordinator da det er mulig og prosjektorganisasjonen har tilstrekkelig kunnskap og kapasiteten. Behov til prosjektorganisasjonens kunnskapsnivå avhenger av målet med modellen med nivå på BIM-anvendelse, nivå på detaljeringsgrad samt størrelse og kompleksitet til prosjektet. Er det et for stort «kunnskapsgap» mellom prosjektorganisasjonen og målet med modellen og type prosjekt, kan det være nødvendig og mest hensiktsmessig å opprette en egendefinert BIM-koordinatorrolle. Fordelen ved å fordele BIM-koordineringsfunksjonen på eksisterende roller er tilsynelatende bedre læring, kompetanseutvikling, implementering/integrering av BIM samt mindre grensesnittproblematikk.
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Alenby, Löfstaf Sara. "Brf Norrby." Thesis, KTH, Arkitektur, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-298428.

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I ett allt mer stressat samhälle vill jag skapa bostäder som blir en lugn plats i vardagen. Jag vill leka med konceptet där naturen möter staden och erbjuda ett boende där möjligheten till att ta en kaffe på ett fik några trappor ner är lika nära som en lugn promenad i naturen. Jag vill ge chansen att gå ut direkt i skogen eller njuta av naturens fördelar från den egna balkongen.  Alla val i projektet, så som planernas utformning, fasadens estetik och val av material har utgått från naturen. Planerna ger varje lägenhet oavsett storlek samma möjligheter att ta del av naturen utanför. Varje lägenhet får varsin balkong och fönsternisch med samma mått för att öppna upp mot skogen. Balkongerna förses med vikdörrar för möjlighet att öppna upp hela glaspartiet och tänja på gränsen mellan ute och inne.  Fasaderna speglar omgivningen. Fasaden mot skogen spelar naturens lekfullhet och öppnar upp med stora fönster i de sociala ytorna. Fönsternischer och balkonger placeras omlott för  skapa en rörelse i fasaden och ge varje balkong avskildhet mot grannar. Fasaden mot gatan speglar istället gatans strikta struktur med mindre fönster och raka enkla linjer.
My project aims to create calm place to live in the stressful society of today. I want to play with the concept where the city street meets nature and precent a living space where the opportunity to grab a coffee in a café a few stories down is as close as a calm walk in the woods. My project creates a home where nature is close, both inside and outside.  Every decision I made in this project is made in consideration of the surrounding nature. Everything from plans, the esthetics of the fasades and the decisions on what materials to work with. All the apartments are given an equally sized balcony and window facing the forest even if the apartment varies in size to give everyone the same opportunity to be close to nature. The balconies have folding doors to make it possible to open up the wall and loosen the line between inside and outside.  The facade facing the street mimics the strict structure of the road with smaller windows and straight lines. The facade facing the forest mirrors the playfulness of nature. The balconies and windows are stacked in a pattern to make a movement in the facade and to create privacy for the balconies.
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Gillerberg, Katarina, and Niklas Tellbe. "Den goda matematikläraren : Vad gör en bra matematiklärare bra?" Thesis, Högskolan i Borås, Institutionen för Pedagogik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-16998.

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BakgrundI bakgrunden gör vi först en historisk tillbakablick på läraren och lärarrollen. Därefter beskriver vi kompetens i allmänhet och lärarkompetens i synnerhet samt de delar som tillsammans formar den helhet som lärarrollen innebär. Vi berör även centrala styrdokument samt andra sociala påverkansfaktorer på yrket.SyfteDenna studie avser att öka förståelsen för vilka förväntningar som matematiklärare möter. Har elever, vårdnadshavare, matematiklärare och skolledare samma syn på vad en god matematiklärare är?MetodArbetet är en kvantitativ studie och som redskap användes en enkätundersökning. Enkäten genomfördes med elever i årskurs 8 och 9 och deras vårdnadshavare samt matematiklärare och skolledare.ResultatResultatet visar att undersökningens fyra grupper; elever, vårdnadshavare, matematiklärare och skolledare, har en förhållandevis samstämmig syn på vad som gör en bra matematiklärare bra. Denna samstämmighet mellan grupperna kan förklaras genom att bilden på ”Den goda matematikläraren” inte enbart är en individuell åsikt utan den skapas i det sociala samspelet med andra individer och grupper. Bilden på ”Den goda matematikläraren” skapas inte bara inom skolans värld utan påverkas också av historien och politiska svängningar. Dessutom befästs bilden av rapportering i media.
Program: Lärarutbildningen
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Prejner, Magnus. "BIM Undersökning : Undersökning av kompetens och erfarenhet för BIM." Thesis, Umeå universitet, Institutionen för tillämpad fysik och elektronik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-136112.

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BIM är ett steg i rätt riktning för att klara av den höga produktionstakten som krävs för populationsökningen i Sverige samt den rådande bostadsbristen. Det är viktigt att alla små och medelstora byggföretag hänger med på den omfattande digitaliseringen som sker av byggsektorn för att kunna fortsätta vara konkurrenskraftiga i både Sverige och Europa. Increase Competence in Northern Building är ett projekt som startat för att se till att små och medelstora företag i Norden fortsätter att vara konkurrenskraftiga i Europa. ICNB är ett interregnord projekt tillsammans med Norge och Finland.   Building Information Modeling avser processer att hantera information gällande en byggnads hela livscykel eller delar av den. Det finns en mängd fördelar med att använda BIM. Det är även en av de största faktorerna till att det är viktigt att hänga med i digitaliseringen för att fortsätta vara konkurrenskraftiga i Europa. Genom intervjustudie med olika branschorganisationer och ett par företag tillhörande respektive branschgren ska kompetens och erfarenhet för BIM undersökas.   Resultatet visar att företagen är eniga i de positiva aspekterna av BIM-användning. Fokuset på kompetensutbildningar varierar mellan konsultföretagen och NCC, där det huvudsakliga syftet med utbildningarna är den största skillnaden mellan dem. Konsultföretagen och NCC utbildar rent praktiskt men NCC jobbar även med att utveckla tankesättet och förståelsen för BIM.
Building Information Modeling is a step in the right path to be able to handle the production rate that is needed for the increase in population in Sweden and handle the current housing shortage. It is important that the small and medium sized enterprises follow the extensive digitization which is happening to the construction sector, and it is also essential to keep being competitive in both Sweden and Europe. Increase Competence in Northern Building is a project which started to make sure the small and medium sized enterprises from the Nordic countries keep being competitive in Europe. ICNB is an interregional project together with Norway and Finland.   Building Information Modeling refers to the process of handling information regarding a buildings whole life cycle or parts of it. There are plenty of benefits from using BIM, and it is also one of the biggest reasons that it is important to follow this digitization to keep being competitive in Europe. Through interviews with different trade organizations and a couple of companies from each industry branch will competence and experience for BIM be investigated.   The results show that the companies agree on the positive aspects with usage of BIM. It varies a lot between NCC and the consulting companies what focus the educations have, where the main purpose with the educations is the biggest difference between them. The consulting companies educate purely to be able to use the software practically, where NCC also works with developing the mind-set and understanding for BIM.
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Holmberg, Marc. "Life Time BoM : BoM-effektivisering ur ett Lean-perspektiv." Thesis, Umeå universitet, Institutionen för tillämpad fysik och elektronik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-165185.

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Beskrivning och analys av ett effektiviseringsprojekt på Sanminas fabrik i Örnsköldsvik. Projektet ska effektivisera BoM-hanteringsprocessen primärt genom tre förändringar. 1: Införa en BoM istället för flera. 2: Datorstöd istället för manuell hante-ring. 3: En konform hantering för alla projekt. Analysen av projektet grundas påLean-principer. Centrala begrepp som Lean och BoM beskrivs. En kvalitativ studiegenomförs med en fokusgrupp bestående av komponentingenjörer. Resultatet fråndenna ligger till grund för analysen. Ny metodik tolkas som effektivare än gammalmetodik på alla tre relevanta punkter. Ny metodik löser dock inte alla de bristersom finns i den gamla processen. Detta då de verktyg avsedda för interna processerinte har större inverkan på externa problem. Förändringarna tolkas som ett steg moten mer Lean BoM-hanteringsprocess. Fullständig analys kommer kunna genomförasnär ny metodik är implementerad. Diskussion kring tolkning av data och osäkerhet i analys av densamma. Detta då datan är kvalitativ.
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A, Taher Ali. "BIM Software Capability and Interoperability Analysis : An analytical approach toward structural usage of BIM software (S-BIM)." Thesis, KTH, Byggnadsteknik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-184856.

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This study focused on the structuralanalysis of BIM models. Different commercial software (Autodesk products and Rhinoceros)are presented through modelling and analysis of different structures with varying complexity,section properties, geometry, and material. Beside the commercial software, differentarchitectural and different tools for structural analysis are evaluated (dynamo, grasshopper,add-on tool, direct link, indirect link via IFC).
BIM and Structural BIM (S-BIM)
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Gabrielsson, Denise. "Bra eller mindre bra : Elevers uppfattningar om bilder och konst." Thesis, Konstfack, IBIS - Institutionen för bild- och slöjdpedagogik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-6171.

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Mot bakgrund av bildämnets centrala innehåll där det tydligt framgår att eleverna ska få tillfälle till att “läsa, skriva och samtala om bilders utformning och budskap” så är denna undersökning baserad på elevers egna kommentarer kring bilder och annan samtida konst.[1]   Denna undersökning har som avsikt att diskutera konst ur ett elevperspektiv. Eleverna har i ett intervjusammanhang fått definiera vad de uppfattar som bra respektive mindre bra bildkonst samt fått chansen att beskriva vad de själva anser att det generella begreppet konst innebär. I samtalen med eleverna så har det diskuterats tekniker, färgval och uttryck, samt ifall det finns hierarkier i dessa element. Empirin har sedan analyserats utifrån ett socialkonstruktionistiskt perspektiv där yttre påverkan så som tradition och trender tas med i beräkningen.   Undersökningens syfte är att få en inblick i elevers förförståelse kring konst för att kritiskt kunna reflektera och göra väl övervägda val i bildundervisningen som känns samtida och med tydlig koppling till den kultur vi upplever utanför skolans diskurs.   Som gestaltande del till detta arbete har jag under intervjuerna låtit eleverna ge mig direktiv om vad för element som bör finnas med för att man ska uppleva en målning som bra, och utifrån dessa direktiv har jag målat en tavla. [1]Sverige, Skolverket (2011). Läroplan för grundskolan, förskoleklassen och fritidshemmet 2011. Stockholm: Skolverket.
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Herrera, Erik. "Byggnadsinformationsmodellering (BIM) - Användning under byggprocessen : Möjligheter och hinder med BIM." Thesis, Mälardalens högskola, Akademin för ekonomi, samhälle och teknik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-30924.

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ABSTRACT The construction industry represents one of the largest and most important industries in Sweden with a large throughput per year. Problems often arise in construction projects which lead to unnecessary construction costs, material costs and waste of time. A solution to those problems can be BIM-Building Information Modeling. BIM is a collective concept of how information is created, stored and used in different stages using a BIM 3D-model. The information should contain important data like height, volume, area, pressure etc. and be digital, measurable and available throughout the whole construction process.    The purpose of this study is to explore how BIM can make the construction industry more efficient regarding construction costs and time and to obtain a comprehensive view of BIM concept and functions during the construction process. The theoretical part includes benefits and disadvantages of BIM during the project planning, production and management stages. The implementation part describes the background of several of the interviewed actors and the implementation of a BIM-model in the program Autodesk Revit. The results are mainly based on interviews of different actors from project planning, production and management stages, but also from a BIM-model of a simple component. The interview result is a summary and reports the features and benefits of the use of BIM.  Former research in one residential shows that BIM perhaps give a saving in 5.15% of the costs. In conclusion BIM represents many advantages that will change and improve the construction process including time saving and less costs. BIM will be the leading approach in the construction industry with more education and better adapted software.
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Österblom, Fredrik, and Andreas Thunell. "BIM: KOMMUNIKATION MELLAN PROJEKTERING OCH PRODUKTION : - Hur BIM effektiviserar informationsflödet." Thesis, KTH, Byggteknik och design, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-192687.

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Denna rapport syftar till att bistå projekterings- och produktionspersonal med effektiviserande verktyg och metoder för att med BIM som bas öka och förenkla informationsutbytet. NCC använder idag BIM-metoder för projektering av projekt, däremot nyttjas inte BIM-metodernas fulla potential för samarbetet mellan disciplinerna i projekten.   För att undersöka behovet inom produktionen hölls intervjuer med personal från ett brett spektrum av åldrar och befattningar. Intervjuerna låg sedan till grund för kriterier till utvärdering av BIM-verktyg. Intervjuerna hölls även med personal med befattningar som projekteringsledare, modellsamordnare och konstruktör, för att med deras kunskaper utvärdera BIM-verktyg.   För att på ett verklighetsförankrat vis utvärdera digitala verktyg i form av BIM-verktyg modellerades ett hus i Tekla Structures 21.1 och Revit 2015. Även A- och K-modellerna för NCCs projekt Trollhättan 33, T33 fanns att tillgå för tester.   Från utvärderingarna utkristalliserades två program som författarna anser vara bäst i respektive stadium av byggprocessen i det studerade projektet, T33. Solibri Model Checker, SMC anses som bäst lämpat verktyg i projekteringsskedet och Trimble Connect anses bäst under produktionsskedet. Solibri Model Checker har bäst möjligheter för validering och kvalitetskontroller och Trimble Connect är ett verktyg där modeller och handlingar kan lagras för enkel kommunikation och samarbete i projektgrupper. Verktyget har även möjlighet att visuellt presentera modeller och handlingar på en dator, surfplatta eller mobiltelefon. De BIM-verktyg som utvärderades var: Solibri Model Checker v9.6 Autodesk Navisworks Manage 2016 Autodesk BIM 360 Glue Trimble Tekla BIMsight Trimble Connect
The purpose of this report is to enable project management and construction personnel to use BIM tools and methods more efficiently. Although NCC is currently using some functionality of such digital tools, NCC is not using the full tool suite to better manage their projects, specifically to leverage the cross discipline collaboration capabilities.   In order to gather a comprehensive view of construction personnel requirements, interviews were conducted across a varied and wide range of age, seniority, and job position. These interviews formed the basis for the evaluation criteria of the BIM tools. Additional interviews were held with other staff, including project leads, model coordinators and construction engineers to ensure their knowledge was incorporated into the evaluation.   To compliment the interviews, and further evaluate the digital tools for cross collaboration capabilities a house was modeled in Tekla Structures and Revit. Also the architectural and construction models of NCC project Trollhättan 33, T33, was available for testing.   Two programs emerged as ‘best in class’ post the assessment, differentiated primarily by which phase of the construction lifecycle they were used for. Solibri Model Checker, SMC was considered most suitable tool in the project management phase and Trimble Connect considered best during the construction phase. SMC is suited for validation and quality control and Trimble Connect is a tool, in which models and documents can be stored for easy collaboration in project teams as well as visualizing models, which are easily shared via computer, tablet or mobile phone. The following BIM tools were tested: Solibri Model Checker v9.6 Navisworks Manage 2016 Autodesk BIM 360 Glue Trimble Tekla BIMsight Trimble Connect
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Thunell, Andreas, and Fredrik Österblom. "BIM: KOMMUNIKATION MELLAN PROJEKTERING OCH PRODUKTION : Hur BIM effektiviserar informationsflödet." Thesis, KTH, Byggteknik och design, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-192901.

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