Dissertations / Theses on the topic 'BRG'
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Bock, Vanessa Leonie. "The Role of Brm, Brg-1, Snail 1 and Snail 2 in the Progression of Non-Melanoma Skin Cancer." Thesis, The University of Sydney, 2008. http://hdl.handle.net/2123/4091.
Full textBock, Vanessa Leonie. "The Role of Brm, Brg-1, Snail 1 and Snail 2 in the Progression of Non-Melanoma Skin Cancer." University of Sydney, 2008. http://hdl.handle.net/2123/4091.
Full textNon-melanoma skin cancer (NMSC) is the most common human cancer worldwide. Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) make up almost all NMSC. SCC usually arises from actinic keratosis (AK) as a result of exposure to sunlight. SCC and AK provide a useful clinical model to investigate changes involved in the progression of NMSC. This project examines the expression of Brm, Brg-1, Snail 1 and Snail 2 in the progression of NMSC. Brm and Brg-1 are subunits of the SWI/SNF chromatin-remodelling complex which is involved in regulating the access of cell machinery to DNA by altering the structure of chromatin. It has been suggested that loss of this function is involved in carcinogenesis as the cell is unable to access to DNA normally in order to repair mutations or activate apoptosis. The loss of Brm or Brg-1 has been described in several human cancers. Snail 1 and Snail 2 are zinc-finger transcription factors that are known for their role in epithelial to mesenchymal transition (EMT), a process vital to embryological development. Increased expression of these factors leads to a loss of cell-cell adhesion and a migratory phenotype and has been described in some human cancers. In this project, double-label immunohistochemistry was used to determine the relative expression of these proteins in human SCC, BCC, AK and normal skin. The expression of Snail was unable to be determined due to poor specificity of the antibodies used. The expression of both Brm and Brg-1 proteins was found to be dramatically and consistently decreased in SCC and BCC when compared to normal skin and AK. This loss of Brm and Brg-1 occured as the tumour progressed from benign AK to malignant SCC. This finding suggests that the loss of either Brm or Brg-1 constitutes a key step in carcinogenesis. The results of this study identify Brm and Brg-1 as putative tumour suppressors involved in the progression of non-melanoma skin cancer from benign to malignant.
STROBECK, MATTHEW WILLIAM. "THE ROLE OF CHROMATIN REMODELING IN RB-MEDIATED CELL CYCLE ARREST." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1014728057.
Full textOlson, Ted. "The 1927 Bristol Sessions: The Big Bang, or the Big Brag of Country Music?" Digital Commons @ East Tennessee State University, 2015. https://dc.etsu.edu/etsu-works/1208.
Full textPilgren, Ludvig. "Borg, berg och bygd. : Selaötraktens fornborgar under den mellersta järnåldern." Thesis, Stockholms universitet, Institutionen för arkeologi och antikens kultur, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-102046.
Full textTosato, João Miguel Toledo. "Segregação no transporte de fertilizantes comercializados em embalagens "BiG Bag"." UNIVERSIDADE ESTADUAL DE PONTA GROSSA, 2006. http://tede2.uepg.br/jspui/handle/prefix/2234.
Full textThe majority of mineral fertilizers used in Brazil are sold in the form of granules mixture in order to provide, lower storage and transportation costs, lower probability of hardening, easier handling and also to simplify its use. Despite the advantages mentioned, such mixtures, which might present two or three primary macronutrients, secondary macronutrients and micronutrients, must have these nutrients uniformly distributed, so that the distribution in the field is homogeneous. However, in this kind of mixture some problems of heterogeneity might occur due to the segregation of granules, which might result in segregation of nutrients that will produce irregular application. The segregation is worrying concerning the application of the fertilizer as well as the sampling by the inspector, once it might generate analysis result that does not match the product real composition. The volume of fertilizers in a Big Bag makes it impossible for the inspector to homogenize the product prior to sampling, as required by law, in the case of smaller packets, thus requiring its own sampling methodology. Therefore, with the aim of evaluating the segregation of fertilizers and determining a sampling methodology for the Big Bag packaging, a study was developed, based on two formulas 02-30-10 and 12-15-15 distributed into four Big Bags each. Three sampling at three different times were carried out. The first was performed soon after packaging, the second, after the Big Bags had been transported on a truck for 407 km and the last after 696 km, both on dirty road and on asphalt. A conic tip double tube steering steel probe, for the sampling of five distinct horizontal levels, five vertical, one in the middle and one in each corner of the packet as well as one diagonal, which went through granulometric and chemical analysis individually. One compound sample was produced by pushing the probe vertically at three distinct points, and later on adding to the four packets portions for analysis. The results of granulometric and chemical analysis , at several points of sampling carried out in the vertical, horizontal e diagonal as well as the compound, after packaging and transportation of the Big Bags, in both formulas studied, show that if a grain mixture fertilizer is produced with raw-material with granules of homogeneous size, within the variation of SGN ± 5%, it presents fewer segregation problems regardless the sampling points mentioned, according to what happened to the formula 12-15-15, and the use of certain raw-material with granules which are incompatible to the other components in the mixture, lead to condenation of the product both chemically and granulometrically, according to what happened to the formula 02-30-10. The compound sample method proved itself efficient despite failing the granulometric analysis of the formula 02-30-10 (after packaging and transportation for 696 km), due to greater amount, size and round format of the triple superphosphate granules (TSP).
Os fertilizantes minerais utilizados no Brasil são em sua grande maioria comercializados na forma de misturas de grânulos por propiciar, menores custos de armazenamento e transporte, além de apresentarem menor possibilidade de empedramento, maior facilidade de manuseio, simplificando a sua aplicação. Apesar das vantagens citadas, estas misturas, que podem apresentar dois ou três macronutrientes primários, macronutrientes secundários e micronutrientes, é de fundamental importância que os nutrientes estejam uniformemente distribuídos em todo o seu volume, para que haja uma distribuição homogênea na área de cultivo. Contudo, neste tipo de mistura podem ocorrer problemas de heterogeneidade pela segregação dos grânulos que também resultará na separação dos nutrientes, ocasionando uma aplicação irregular. A segregação é preocupante tanto do ponto de vista da aplicação do fertilizante, quanto do momento da amostragem por parte da fiscalização, podendo obter um resultado de análise que não corresponde à realidade da composição do produto. O volume de fertilizantes acondicionado em embalagem Big Bag impossibilita aos fiscais a homogeneização do produto previamente à amostragem, como é estabelecido pela legislação, no caso de embalagens menores, necessitando, portanto de uma metodologia de amostragem apropriada. Diante destes fatos, com o objetivo de avaliar a segregação de fertilizantes e determinar uma metodologia de amostragem para embalagem tipo Big Bag foi desenvolvido um estudo com duas fórmulas 02-30-10 e 12-15-15 acondicionadas em quatro Big Bag cada uma. Foram estabelecidas amostragens em três momentos distintos, sendo uma logo após o envase, outra após os Big Bags terem sido transportados em caminhão por 407 Km e a última após completar 696 Km, realizados em estradas de asfalto e de terra. Foi utilizada uma sonda de aço inox cano duplo com ponta cônica, para amostragem de cinco níveis distintos na horizontal, cinco no sentido vertical, uma no centro e em cada um dos cantos da embalagem e uma na diagonal, as quais individualmente foram acondicionadas para análise química e granulométrica. Retirou-se também uma amostra composta, que foi feita inserindo verticalmente a sonda em cada Big Bag em três pontos distintos, e depois foram juntadas as porções das quatro embalagens para a realização das análises. Os resultados das análises químicas e de granulometria, nos vários pontos de amostragens realizados na vertical, horizontal, diagonal, e composta, após o envase e os transportes dos Big Bag, nas duas fórmulas pesquisadas, nos indicam que se um fertilizante mistura de grânulos for elaborado com matérias-primas com grânulos de tamanhos homogêneos, dentro da variação de ± 5% do SGN, apresentam menores problemas de segregação independente dos pontos de amostragens citados, conforme o ocorrido com a fórmula 12-15-15, e o uso de determinada matéria-prima com grânulos incompatíveis aos demais componentes da mistura, levam à condenação do produto tanto química quanto granulometricamente, conforme o ocorrido com a fórmula 02- 30-10. O método de amostra composta mostrou ser eficiente apesar da reprovação granulométrica da formulação 02-30-10 (após envase e transporte de 696 km), fato justificado pela maior quantidade, tamanho e formato arredondado dos grânulos do superfosfato triplo (TSP).
Zhang, Min. "The role of SWI/SNF in regulating smooth muscle differentiation." Thesis, Connect to resource online, 2009. http://hdl.handle.net/1805/2024.
Full textTitle from screen (viewed on December 1, 2009). Department of Cellular and Integrative Physiology, Indiana University-Purdue University Indianapolis (IUPUI). Advisor(s): B. Paul Herring, Anthony B. Firulli, Frederick M. Pavalko, Simon J. Rhodes. Includes vitae. Includes bibliographical references (leaves 138-149).
AQUINO, SIBELE DIAS DE. "PSYCHOLOGY AT SHOPPING BAG: RELATIONS BETWEEN BIG FIVE, SOCIAL INFLUENCE AND IMPULSE BUYING." PONTIFÍCIA UNIVERSIDADE CATÓLICA DO RIO DE JANEIRO, 2018. http://www.maxwell.vrac.puc-rio.br/Busca_etds.php?strSecao=resultado&nrSeq=35833@1.
Full textCOORDENAÇÃO DE APERFEIÇOAMENTO DO PESSOAL DE ENSINO SUPERIOR
PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTS. DE ENSINO
PROGRAMA DE SUPORTE À PÓS-GRADUAÇÃO DE INSTITUIÇÕES COMUNITÁRIAS DE ENSINO PARTICULARES
A compra por impulso acontece sem reflexão, espontaneamente, e pode ter vários antecedentes. O objetivo desta dissertação foi testar o poder preditivo dos cinco grandes fatores de personalidade sobre a compra por impulso. Para tanto, realizaram-se dois estudos em que 1296 brasileiros, de todos os estados da federação, responderam a um questionário via internet. O estudo 1 teve o objetivo de buscar evidências de validade de um instrumento para aferir a tendência de comprar impulsivamente. Foram encontradas correlações positivas entre a tendência de comprar por impulso, a influência social normativa e traços de impulsividade do consumidor. O instrumento também foi capaz de diferenciar pessoas que fazem lista de compras das que não fazem, e pessoas que preferem ir às compras sozinhas das que preferem comprar acompanhadas. As evidências encontradas suportam o uso do instrumento para o contexto brasileiro. No segundo estudo, foi realizada uma regressão linear múltipla para testar se personalidade e influência social prediriam a compra por impulso. As variáveis investigadas explicaram 23 por cento da variância da compra por impulso. Entre preditores significativos positivos destacaram-se a influência social normativa e o fator de Neuroticismo de personalidade; entre os negativos, destacaram-se o hábito de fazer lista de compra e o fator Conscienciosidade de personalidade. Os resultados confirmam o poder preditivo de fatores de personalidade, influência social e hábitos de consumo sobre o comportamento de compra por impulso. Este estudo aprofunda os achados psicológicos sobre comportamentos de compra, alavancando a disseminação do conhecimento tanto para pesquisadores, quanto para profissionais interessados no tema.
The aim of this study was to test the predictive power of the big five factors of personality on impulse buying. In addition, sexual differences were verified for impulse buying behavior and levels of susceptibility to social influence, as well as relations of purchase with sociodemographic variables and consumption habits. Participants were 1296 Brazilians. The model tested explained 23 percent of the variance of impulse buying, the higher predictive powers were for normative influence and neuroticism, as positive; followed by the habit of making shopping list and conscientiousness, as negative predictors. The results confirm the predictive power of personality factors, consumption habits and socio-demographic variables on impulse buying.
Keenen, Bridget. "The Role of SWI/SNF Chromatin Remodeling Complex in Melanoma." University of Toledo Health Science Campus / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=mco1271819328.
Full textHolm, Anders Larsen Flemming. "To samtidige Kirkegaards og Grundtvigs kritik af hinanden /." Kbh. : Nota, 2009. http://www.e17.dk/bog/18730.
Full textGabriella, Öström, and Högström Lina. "Symtomförekomst och noceboeffekter hos individer med byggnadsrelaterad ohälsa." Thesis, Umeå universitet, Institutionen för psykologi, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-149104.
Full textBuilding Related Illness (BRI) is one of several environmental sensitivities. The two constructs Modern Health Worries (MHW) and Somatosensory Amplification (SSA) have both been shown to be linked to nocebo and are often reported by people with environmental sensitivities. The first purpose of this paper was to increase the understanding of symptoms that characterize BRI, which was investigated via 20 items selected from The Idiopathic Enviromental Intolerance Symptom Inventory (IEISI) that complies with WHO's list of BRI symptoms. The second purpose was to increase knowledge about the role of nocebo in BRI, which was investigated via Modern Health Worries Scale (MHWS) and Somatosensory Amplification Scale (SSAS). Data was obtained from an ongoing study at Umeå University. The sample consisted of 79 individuals who reported that they experienced BRI symptoms each week. Data was analyzed via correlation analyzes. The group showed variability concerning which and how many symptoms the individuals reported. The results from the correlation analyzes showed that nocebo did not play a significant role in the reporting of BRI symptoms in the selection group. The study showed that the group of BRI patients neither worry more than the norm nor was particularly sensitive to sensory impressions.
Mossberg, Magnus. "Mental kompetens : Tänk bra – må bra – prestera bra." Thesis, Halmstad University, School of Teacher Education (LUT), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-2157.
Full textSYFTE: Jag har i mitt yrke erfarit att många elever upplever skolan som stressande. Studier
stöder denna iakttagelse och visar att för många tonåringar är skolan den i särklass största
stressfaktorn. Vidare ökar stressrelaterade sjukdomar bland vuxna kraftigt. Detta gav mig en
ide att inom skolans ram försöka agera preventivt och inspirerad av coachning och kognitiv
beteendeterapi satte jag samman en kurs. Här undersökte jag huruvida träning i mental
kompetens; kunskap om kroppens känslosystem, språk för känslor, stresshantering och
problemlösningsstrategier, skulle kunna ge elever större känsla av beredskap för att hantera
livet i ett modern komplext samhälle och därmed en högre livskvalitet. METOD: Innan och
efter kursen utvärderades elevernas förmåga att hantera för dem stressiga situationer samt
aktionsberedskap i situationer som kräver handling. Under kursens gång gjordes kontinuerliga
utvärderingar och dessutom genomfördes en muntlig och skriftlig utvärdering vid kursens
slut. Vidare förde jag en personlig loggbok där för mig viktiga iakttagelser noterades.
RESULTAT: Eleverna visade avsevärd förbättring av de undersökta kompetenserna.
Dessutom upplevde så gott som samtliga att kursen behandlat för dem viktiga saker och att de
kände sig psykiskt starkare av kursen. SLUTSATS: Undersökningen visar att det på kort tid
går att avsevärt höja elevers förmågor inom mental kompetens. Skolan bör undersöka
huruvida undervisning i mental kompetens bör ingå i den ordinarie undervisningen.
Boman, Johanna, and Josephine Ekhager. "Hur bra är bra tills bra blir dåligt?" Thesis, Högskolan i Gävle, Avdelningen för ekonomi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-34173.
Full textOrtis, Fernanda. "Papel de BRG1 e Brm, reguladores globais de transcrição, na reversão fenotípica de células ST1 pela ação de glicocorticóides." Universidade de São Paulo, 2002. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-26072007-053713/.
Full textGlucocorticoid hormones (GCs) have been used as anti-inflammatory and anti-tumor agents, acting via nuclear receptors (GR) and being dependent on remodeling of the chromatin structure. As components of the global chromatin remodeling transcription complex (SWI/SNF), Brm and BRG-1 proteins play a key role in the action of GR. In order to study the mechanisms of action of GCs, we have been using the ST1 and P7 cell lines, derived from the C6, a rat glioma cell line. P7 is insensitive to the GC treatment, while ST1 displays a complete phenotypic reversion from tumoral to normal, including a G1-specific block in the cell cycle. A Brm and BRG1-specific polyclonal antiserum was generated, in rabbit, using recombinant hBRG1 protein as antigen. This antiserum was used to analyze the levels of Brm and BRG1 in these two cell lines, under GC treatment. While Brm is induced by GC, in ST1 cells, the basal level of Brm, in P7 cells, is relatively high, remaining unchanged under GC treatment. The possibility of brm mutations occurring in the P7 cells, was analyzed by DNA sequencing. Overexpression of brm and BRG1 in P7 cells led to morphological alterations (cell flattening) and decreased colony formation in agarose suspension and in solid substrate. Some of these clones became partially responsive to GC, when compared to the ST1 cell line. Co-immunoprecipitation assays revealed some differences in the SWI/SNF complex between ST1 and P7 cells.
O'Reilly, Noelle. "By the Big Big River." The Ohio State University, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=osu1492707144983958.
Full textBerg, Trenton Jeffery. "Compact, mid-infared laser source for remote sensing of gas effluents." Thesis, Montana State University, 2009. http://etd.lib.montana.edu/etd/2009/berg/BergT1209.pdf.
Full textBerg, Wayne Carl Jr. "Images in the labyrinth a reading of symbol and archetype in four quartets /." Thesis, Montana State University, 2007. http://etd.lib.montana.edu/etd/2007/berg/BergW0507.pdf.
Full textTolley, Andrew James. "From big-crunch to big-bang." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.620026.
Full textKocz, Nick. "Big Baby Hot, Big Baby Cold." Thesis, Virginia Tech, 2009. http://hdl.handle.net/10919/77493.
Full textMaster of Fine Arts
Pedreira, Vanda do Amaral V. "Espectroscopia Raman em compostos KBr-Br2, KI-Br2 e do HOPG-Br2." [s.n.], 1996. http://repositorio.unicamp.br/jspui/handle/REPOSIP/277833.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Fisica Gleb Wataghin
Made available in DSpace on 2018-07-21T21:13:10Z (GMT). No. of bitstreams: 1 Pedreira_VandadoAmaralV_M.pdf: 844584 bytes, checksum: 2a2b2be7ecb54390cbe9dab4102cf709 (MD5) Previous issue date: 1996
Resumo: Os cristais iônicos KBr e KI não apresentam atividade Raman. Espectros Raman destes cristais, após imersão em bromo líquido, exibiram linhas com freqüências identificadas como sendo devida aos compostos KBr3 e IBr, ao Br2 e às formas alotrópicas 79Br -79Br. 79Br -81Br e 81Br -81Br e aos íons Br3- e Br5-. -Espectros Raman do grafite pirolítico altamente orientado (HOPG) intercalados com Br2 foram estudados. O estágio encontrado foi n=2, evidenciado pelo pico intenso em w = 244 cm-1 e pelos seus harmônicos 2w0 ,3w0 ,4w0 ... . Estruturas menores foram observadas na região espectral dominada pelo bromo sólido
Abstract: The ionics crystals KBr and KI do not present Raman activity. Raman spectra of these crystals after immersing in liquid bromine exhibits lines with frequencies identified as been due to the compounds KBr3 and IBr, to the alotrophics forms 79Br - 79Br, 79Br- 81Br and 81Br - 81Br and to the ions Br3- and Br5-. -Raman spectra of highly oriented pyrolitic graphite (HOPG) intercalated with Br2 were also investigated. The stage number found was n=2, evidenced by the intense peak in w0 = 244 cm-1 and by its harmonics 2w0, 3w0, ... . Minor structures were also observed in the spectral region dominated by the solid bromine
Mestrado
Física
Mestre em Física
Castro, Allende Marcos. "Skola i förändring : Bra betyg = Bra demokrat?" Thesis, Linnéuniversitetet, Institutionen för statsvetenskap (ST), 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-27302.
Full textEdwards, Mannheimer Rebecca. "Mammabarnanstalt : Barn i fängelse - bra för barnet, bra för mamman, bra för samhället." Thesis, KTH, Arkitektur, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-34754.
Full textLundvall, Helena. "Big data = Big money? : En kvantitativ studie om big data, förtroende och köp online." Thesis, Uppsala universitet, Företagsekonomiska institutionen, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-451065.
Full textArrieta, Solano Lourdes Mariana. "Diseño de un sistema de costeo por órdenes para la toma de decisiones operativas en la empresa Big Bag Perú S.A.C, Chiclayo 2018." Bachelor's thesis, Universidad Católica Santo Toribio de Mogrovejo, 2021. http://hdl.handle.net/20.500.12423/3515.
Full textHermann, Danielle Christa. "Big women." [Ames, Iowa : Iowa State University], 2008.
Find full textGordon, Derek, and David Rogoff. "Big Brat." Digital Commons at Loyola Marymount University and Loyola Law School, 2011. https://digitalcommons.lmu.edu/etd/64.
Full textBarrera, Reyes Keiko Dallana, Ocampo Christian Castañeda, Arenas Geannel Yani Rosas, and Condorena Natalia Andrea Zegarra. "KEY BAG." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/653102.
Full textFor many time, plastic bags had been helpful for the costumers, many of them were got for free in every supermarket and shops. However, Nowadays there is the Law N° 30884, which made every customer have a bag to carry their products, otherwise the customer could buy a bag at the supermarket or shop they are at the moment. That is the moment when our project is born, “KEYBAG”, is a key chain bag which is designed for not planned shopping, it gives you the advantage to have a bag in your key chain, it has a thermic cloth bag which protects your products and the environment, it also allows you to organize your products, and use it to go shopping o buy you products many times. Our tempting project has an estimated time of 5 years, requires an initial investment of S/. 28005.53 and after the financial analysis it determined that the external financing S/ 11,202.21, and to the end of the project. Also, the return of investment would be a year after the commercial activities start. Finally, following the current trend about the responsible consumption we are using eco-friendly and resistant materials, what makes KeyBag a product that generates a positive impact for the environment.
Trabajo de investigación
Jennings, Brandon Davis. "Big Men." Bowling Green State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1245613714.
Full textAlenby, Löfstaf Sara. "Brf Norrby." Thesis, KTH, Arkitektur, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-298428.
Full textMy project aims to create calm place to live in the stressful society of today. I want to play with the concept where the city street meets nature and precent a living space where the opportunity to grab a coffee in a café a few stories down is as close as a calm walk in the woods. My project creates a home where nature is close, both inside and outside. Every decision I made in this project is made in consideration of the surrounding nature. Everything from plans, the esthetics of the fasades and the decisions on what materials to work with. All the apartments are given an equally sized balcony and window facing the forest even if the apartment varies in size to give everyone the same opportunity to be close to nature. The balconies have folding doors to make it possible to open up the wall and loosen the line between inside and outside. The facade facing the street mimics the strict structure of the road with smaller windows and straight lines. The facade facing the forest mirrors the playfulness of nature. The balconies and windows are stacked in a pattern to make a movement in the facade and to create privacy for the balconies.
Catter, Sánchez Diego Armando, Palomino Javier Ronald Estocalenko, and Garivoto Ámbar Beatriz Alvarado. "Big Foodie." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/624805.
Full textCreation of an application, where subscribers can have the benefit of being able to locate and discover the gourmet and delicatessen stores. The target audience is men and women between 25 and 45 years old, of socioeconomic level B, B- +. A. A- +, according to the study carried out by Arellano Marketing, the targeted districts are Jesús María, Lince, Pueblo libre, Magdalena, San Miguel, Miraflores, San Isidro, San Borja, Surco, La Molina and Barranco, which will allow us to have a larger target population. For the project has been considered a 5-year evaluation where subscribers are divided into customers "Discover" and "Premium", the estimate of subscribers for the year 2019 is 12,301 on the platform "Discover" and 1168 in the version " Premium ", with a linear growth of 10% per year.
Trabajo de investigación
Hansen, Simon, and Erik Markow. "Big Data : Implementation av Big Data i offentlig verksamhet." Thesis, Högskolan i Halmstad, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-38756.
Full textGillerberg, Katarina, and Niklas Tellbe. "Den goda matematikläraren : Vad gör en bra matematiklärare bra?" Thesis, Högskolan i Borås, Institutionen för Pedagogik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:hb:diva-16998.
Full textProgram: Lärarutbildningen
Le, Loarer François. "Dérégulation du complexe BAF dans les sarcomes épithélioïdes et leur variants génétiques." Thesis, Lyon 1, 2015. http://www.theses.fr/2015LYO10127.
Full textEpithelioid sarcomas (ES) display loss of SMARCB1 nuclear expression in 85% of cases. SMARCB1 is encoded by a tumor suppressor gene located in 22q11 which was first linked to cancer in malignant rhabdoid tumors. While investigating a series of 40 epithelioid sarcomas with BAC-FISH (Bacterial Artificial Chromosome-Fluorescence In Situ Hybridization), we demonstrated that SMARCB1 loss in ES occurred through genomic deletions in 85% of cases. We were also able to highlight the first case of ES associated with a heterozygous SMARCB1 deletion in the germ line, which feature was previously thought to be restricted to malignant rhadboid tumors (MRT). We subsequently investigated a series of 16 SMARCB1-retained ES to identify its underlying culprit gene with a focus on the candidate tumor suppressor gene SMARCA4. SMARCA4 encodes one of the ATPase subunit of BAF complexes. Interestingly, SMARCB1 is also a core submit of these complexes which regulate chromatin remodeling. We were able to identify a set of 6 cases displaying SMARCA4 inactivation with this discovery cohort. The review of medical records highlighted these cases had similar presentation : all tumors presented with large compressive and aggressive mediastinopulmonary masses. We further recruited 13 cases based on these characteristics including 5 prospective cases. The characterization of their transcriptomes by RNA-sequencing (n=13/19) confirmed their remarkable homogeneity, all our samples clustering together with MRT. However our variant diverge from malignant rhabdoid tumors as it lacks SMARCA4 alteration in the germline (n=0/11) and displays complex polyploidy genetic profiles. We therefore called this new tumor variant “SMARCA4-deficient thoracic sarcoma” (SMARCA4-DTS). The transcriptomic vicinity of SMARCA4-DTS and MRT let foresee they share common therapeutic vulnerabilities
Gabrielsson, Denise. "Bra eller mindre bra : Elevers uppfattningar om bilder och konst." Thesis, Konstfack, IBIS - Institutionen för bild- och slöjdpedagogik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-6171.
Full textNiz, Quevedo Gustavo. "The big crunch/big bang singularity in string/M-theory." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612804.
Full textvon, Strauss Mikael. "The BIG ghost." Licentiate thesis, Stockholms universitet, Fysikum, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-56801.
Full textBaryauno, Linda, and Funda Pektas. "Big Bath Accounting." Thesis, Södertörns högskola, Institutionen för samhällsvetenskaper, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-19342.
Full textTingström, Emilia, and Linus Axelsson. "Varför bestiga berg?" Thesis, Linköpings universitet, Kultur, samhälle, mediegestaltning, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-93288.
Full textLoizou, T. "Describing bog surfaces." Thesis, University of Dundee, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366994.
Full textHansson, Rasmus. "Energiutredning Brf Kruthornet." Thesis, Umeå universitet, Institutionen för tillämpad fysik och elektronik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-122665.
Full textRizk, Raya. "Big Data Validation." Thesis, Uppsala universitet, Informationssystem, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-353850.
Full textLehocký, Gabriel. "Electronic Flight Bag." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2017. http://www.nusl.cz/ntk/nusl-363806.
Full textJaber, Carolin. "Big data visualisering." Thesis, Örebro universitet, Institutionen för naturvetenskap och teknik, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-79898.
Full textPresenting data in graphical forms is important in many different industries in order tounderstand information asset from data that is being collected. The amount of data is growingfast and brings new challenges for visualizing the data in graphical representations. Systemsare dependent on data visualization for detecting defects and faults of productions. Byimproved performance of time series data visualization increases the ability of detectingfaults and defects of productions.This report takes up a methods for visualizing time series data with high velocity in toaccount and discusses how big data of multivariable can be visualized with PCA.
Andersson, Anne-Marie, and Mats Andersson. "Geografi - kunskapens bro." Thesis, Malmö högskola, Lärarutbildningen (LUT), 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-30097.
Full textKúšik, Lukáš. "Electronic Flight Bag." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2021. http://www.nusl.cz/ntk/nusl-449169.
Full textBlahová, Leontýna. "Big Data Governance." Master's thesis, Vysoká škola ekonomická v Praze, 2016. http://www.nusl.cz/ntk/nusl-203994.
Full textDelacruz, Gian. "Punching bag trainer." Click here to view, 2009. http://digitalcommons.calpoly.edu/eesp/11/.
Full textProject advisor: David Braun. Title from PDF title page; viewed on Feb. 4, 2010. Includes bibliographical references. Also available on microfiche.
Casagrande, Federico <1994>. "Big Data Valuation." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19687.
Full textEkström, Jenny, and Tove Johansson. "Den som äter bra, arbetar bra : Skolmatens påverkan - ur ett elevperspektiv." Thesis, University of Kalmar, School of Human Sciences, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hik:diva-1328.
Full textSyftet med vår uppsats är att undersöka hur eleverna upplever att de påverkas av skolmaten. Forskning visar att det finns ett samband mellan matens näringsinnehåll och vår prestationsförmåga. Vår undersökning gjordes i form av kvalitativa intervjuer av 16 elever, från två olika grundskolor. Resultatet av studien visar på ett samband mellan den mat eleverna serveras i skolan och hur väl de klarar av skolarbetet.
Gustafsson, Sofia. "Big money, Big responsibility : A study of active and responsible ownership." Thesis, Umeå University, Umeå School of Business, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1276.
Full textABSTRACT
Social Responsible Investments and Corporate Social Responsibility are terms that have become increasingly important in the business world of today. Fund companies have during the last years increased their work with issues such as human rights, environmental impact and business ethics before making an investment. The trend of today is rather to work as active owners and influence companies to change rather than passively excluding certain industries. Other investors whose business idea is to buy, create value and sell companies also use a very active owner strategy but historically focus has been on issues such as industrial development and financial performance and CSR issues have been left out. With this background I came up with the purpose of this study.
The purpose of this study is to create an understanding of if/how investors work with social responsible investments by engaging in corporate social responsibility issues, mainly during the ownership of a company. Further on the study aims to identify the differences between investment companies compared to fund companies when it comes to interest in and promotion of CSR issues as owners. Finally the study intends to create an understanding for the attitudes towards corporate social responsibility and social responsible investments from the investors’ point of view.
I have chosen to study five investors, two fund companies known for their work as active owners by engaging in CSR issues, and three investment companies who all work with engaging in CSR issues to different degrees. To be able to fulfill the purpose I needed deep information about the subject of study and I therefore chose a qualitative method and collected data from semi structured interviews at the investors’ offices in Stockholm. The empirical data was analyzed and interpreted with theories within the area of CSR, SRI and active ownership. The lack of specific theories on active ownership through engagement in CSR issues required the golden middle road as scientific approach since this approach enabled me to interact between theory and empirical reality.
Conclusions to be drawn from this study is that investment companies do not to a great extent work as social responsible investors by engaging in CSR issues. The reason for this is that the investment companies do not perceive that they are responsible but that the responsibility is rather on each of their holding companies. Another reason for not working with CSR issues is because their shareholders do not require them to do so. There is still a great lack of understanding of CSR and its possible connection to financial performance. If the investment company work with CSR it is either due to risk minimizing reasons or pure philanthropic reasons and not at all based on the fact that CSR can lead to innovation and competitive advantage.
The main difference between the fund companies and investment companies is that the fund companies have formalized their work with SRI and engage actively in CSR issues as owners but only in the so called SRI funds which are a significant small part of total invested capital and it is still hard to integrate CSR into the mainstream analysis. The other difference is that investment companies have greater ability to influence its holding companies if compared to the fund companies, and the investment companies use this possibility but mainly in issues such as strategic planning and financial performance and not so much in social or environmental issues.
KEY CONCEPTS
Following concepts are the key concepts that are central and constantly recurring throughout this study.
• Corporate Social Responsibility
• Social Responsible Investments
• Engagement
• Holding companies
• Active ownership
• Investment companies
• Fund companies