Log in

Relevant bibliographies by topics / Breast Cancer Patients Malaysia / Dissertations / Theses

Dissertations / Theses on the topic 'Breast Cancer Patients Malaysia'

To see the other types of publications on this topic, follow the link: Breast Cancer Patients Malaysia.

Author: Grafiati

Published: 10 December 2022

Last updated: 29 January 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 dissertations / theses for your research on the topic 'Breast Cancer Patients Malaysia.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.

1

Dasch, Kimberly B. "Affective differentiation in breast cancer patients." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 70 p, 2009. http://proquest.umi.com/pqdweb?did=1885670961&sid=7&Fmt=2&clientId=8331&RQT=309&VName=PQD.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Lagergren, Jakob. "Immediate breast reconstruction with implants in breast cancer patients /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-230-9/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Yeung, Shuk-chong Rene. "Self-evaluation of coping resources of cancer patients /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22330914.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Cheng, Wing-ming Edward. "Emotional well-being in Chinese lung cancer patients." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B3197157X.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Wolfman, Jessica Heather Kloss Jacqueline D. "Cancer specific stress and insomnia severity among breast cancer patients /." Philadelphia, Pa. : Drexel University, 2009. http://hdl.handle.net/1860/3024.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Daniels, Tasneem. "Bi-rads final assessment categories in breast cancer patients." Thesis, Cape Peninsula University of Technology, 2019. http://hdl.handle.net/20.500.11838/2969.

Full text

Abstract:

Thesis (MSc (Radiography))--Cape Peninsula University of Technology, 2019
INTRODUCTION: The Breast Imaging Reporting and Data System (BI-RADS) was developed by the American College of Radiology (ACR). The BI-RADS is an internationally accepted method of assessing and reporting on mammograms and breast ultrasound images. The BI-RADS consists of a lexicon (descriptors) and assessment categories. The ACR aimed to standardise mammography reporting and placing the findings in the appropriate assessment category. The aim of this study was to establish the accuracy of the BI-RADS assessment categories for mammography and breast ultrasound images in women diagnosed with breast cancer. METHOD: Data were retrieved from 77 patients who were diagnosed with breast cancer from 1 January 2013 to 31 December 2014. Seven did not meet the inclusion criteria and were excluded. The study sample size was 70 (n=70) patients. All mammography reports included a BI-RADS assessment category of all patients diagnosed with breast cancer within the study period. These reports were analysed and compared with histopathology results. The BI-RADS assessment category and descriptors were collected from the mammogram reports; the histopathology report indicated the type of breast cancer. All reports were obtained from the patients' folders at the research site. In addition, questionnaires were distributed among radiologists to assess whether their experience and training had an influence on the accuracy of reporting in the BI-RADS assessment categories. Descriptive and inferential statistical analysis was used for data analysis. RESULTS: The most common malignancy diagnosed was invasive ductal carcinoma with a total of 70% (n=54), followed by ductal carcinoma in situ with 10.4% (n=8) and invasive lobular carcinoma with 9.1% (n=7). The histology results confirmed breast cancer for all BI-RADS 4 and 5 assessment categories. The mammogram was able to detect 93.5% of abnormalities and breast ultrasound 84.4% of abnormalities in this study sample. Breast ultrasound was used as an adjunct to mammography and hence an overall combined diagnostic rate was 100%. Mammography descriptors: The more common malignancy findings were spiculated mass margin, 35.1% (n=27). Ultrasound descriptors: The more common malignancy findings were hypoechoic echo pattern, 55.8% (n=43). There was no significant association (p=0.152) between the radiologists' years of experience and BI-RADS 3, 4 and 5 assessment category reporting. Of the 15 responses, 67% agreed that the BI-RADS standardises breast imaging reporting and reduces confusion, 33% agreed that the BI-RADS allows better communication between radiologists and referring physicians, and 40% agreed that the BI-RADS clarifies further management for patients by helping to stratify risk management. CONCLUSION: The outcome of this study indicated that the use of BI-RADS assessment categories is useful for predicting the likelihood of malignancy when used correctly. The outcome of BI-RADS 4 and BI-RADS 5 had a positive predictive value of 100%, which corresponded well with histology results. The descriptor findings suggested that spiculated mass margins, irregular-shaped masses, hypoechoic echo pattern and posterior shadowing were high predictors of malignancy and warranted a placement in the BI-RADS 5 assessment category.

APA, Harvard, Vancouver, ISO, and other styles

7

Alburai'Si, Kholoud Mubarak. "Stratification of breast cancer patients : a proteomic approach." Thesis, King's College London (University of London), 2016. https://kclpure.kcl.ac.uk/portal/en/theses/stratification-of-breast-cancer-patients(a8102723-9f21-4495-8401-d3e8ce503968).html.

Full text

Abstract:

Breast cancer represents a heterogeneous collection of different diseases characterized by different pathological and biological features, clinical presentation, clinical behaviour, response to treatment and outcome. In current practice, pathological diagnosis and classification of breast cancer is based mainly on well-established traditional morphologic features. However, morphological features alone do not adequately reveal the molecular heterogeneity and complexity of breast cancer. Still, there are relatively few biomarkers widely used in prognostication in invasive breast cancer and in predicting response to targeted therapies, and even fewer of value in the clinical management of the pre-invasive disease of ductal carcinoma in situ (DCIS). There is therefore an unmet need for biomarkers for better classification, better prediction of prognosis and of prediction of response to therapy for both invasive breast carcinoma and DCIS. The co-expression of a HER2/HER3 combination results in more aggressive tumour growth and is associated with endocrine and chemotherapy resistance, driven not simply by receptor expression but also by signalling via the receptors dimers. Therefore, methods which directly query signalling pathway activation in breast cancer specimens are anticipated to provide important insights into the molecular ‘‘logic’’ that distinguishes cancer from normal tissues and potentially to have an important impact on personalized intervention strategies. The aim of this thesis has been directed at evaluating candidate biomarkers in breast cancer. This has been targeted at examining attributes associated with known functional properties of candidate drivers of disease or resistance to treatment rather than those traditionally based on altered expression of these biomarkers. Specifically, the work was directed at the HER1-3 members of the EGFR family of growth factor receptor in breast cancer. In this project I have in part developed, tested and evaluated two methods, which have the ability to detect protein-protein complexes at a single molecule level and thus allow the study of signalling pathways in situ. The first method is an in-house coincidence detection technology created from two recombinant fusion proteins and the second is a commercially available proximity ligation assay (PLA) method. Both approaches were able to detect the target proteins with high sensitivity and specificity, however the proximity ligation assay was subsequently used here to assess the protein complexes and activation status of the EGFR family in breast cancer patient’s samples. The patient study cohort is derived from a consecutive series of approximately 293 cases of primary operable invasive breast cancers obtained from the Guy’s and St Thomas (King’s Health Partner’s) Breast Cancer Biobank archive presenting between 1990 and 1992. In these cases, 9 different biomarkers were studied for HER family expression level, dimer expression and activation status using proximity ligation assays (PLAs). The relationship between HER activation status, dimer expression and relapse free survival (RFS) was investigated and stratified multivariate regression analysis identified factors influencing patient prognosis. In conclusion, PLA successfully and reproducibly detected HER protein complexes and phosphorylation in vivo. A significant association was identified between high levels of phosphorylated HER2 and reduced recurrence-free survival (RFS) in invasive lobular carcinoma (p = 0.04, HR 0.99, 95% CI: 0.997-1.002). High levels of HER1/HER3 dimers were associated with reduced RFS in T1 (<2cm) breast cancer patients, (p = 0.02, HR 1.84, 95% CI: 1.08-3.13). Similarly, high levels of HER1/HER3 and HER2/HER3 dimers were associated with reduced RFS in breast cancer patients with N1 nodal status (p <0.0001, HR 1.84, 95% CI: 0.58-1.93) and (p <0.0001, HR 0.64, 95% CI: 0.45-0.90) respectively). Work in this thesis demonstrates that in situ detection of HER protein complexes and activation status can be monitored robustly and with specificity in clinical specimens, providing novel prognostic information. This technique was also applied successfully to assess the HER family in a smaller number of DCIS cases. This novel technique and approach could potentially be applied for patient stratification and assist in the selection of more individualized treatment options according to tumour molecular characteristics.

APA, Harvard, Vancouver, ISO, and other styles

8

Molenaar, Jacobus. "Treatment decision support for early breast cancer patients." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2004. http://dare.uva.nl/document/77496.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Blackwelder, Reid B. "Integrative Approaches to Treating Patients with Breast Cancer." Digital Commons @ East Tennessee State University, 2007. https://dc.etsu.edu/etsu-works/6985.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Jansen, Catherine E. "Cognitive function in breast cancer patients undergoing chemotherapy." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3261235.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Donaghy, Kathleen B. "Biopsychosocial factors in breast cancer." Virtual Press, 1997. http://liblink.bsu.edu/uhtbin/catkey/1115723.

Full text

Abstract:

In the treatment of early stage breast cancer, both mastectomy and lumpectomy followed by radiation therapy have been recognized as having similar survival rates. Increasingly, women are being given the opportunity to choose which of these surgical treatment options they wish to pursue. Decisions tend to be made rather quickly, and some women may later regret their treatment choice. In this study, an instrument (Breast Cancer Treatment Inventory (BCTI)) was developed that identified five primary sources of influence that affect women's breast cancer treatment decisions: cosmetic outcome, preparedness, physician's choice, short-term effects, and long-term effects. Items were generated and refined by oncology professionals and breast cancer survivors, followed by a pilot study conducted with members of a breast cancer support group. The resulting 28-item scale was completed by 139 early stage breast cancer patients. A series of oblique factor analyses yielded a five-factor solution with reliabilities ranging from .66 - .87. Content validity was enhanced by involving oncology experts and women with breast cancer in the item generation procedures. Use of the BCTI may assist women through a methodical and effective decision-making process. The BCTI may also be appropriate for research studiesinvolving the process and prediction of treatment selection since it meets requirements for ease of administration, brevity, reliability, and validity.
Department of Counseling Psychology and Guidance Services

APA, Harvard, Vancouver, ISO, and other styles

12

Mak, Wai-ming Vivian. "Psychological predictors of marital adjustment in breast cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B29726426.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

Bailey, A. Kathleen (Ann Kathleen). "Interactional Patterns in Families of Patients with Breast Cancer." Thesis, North Texas State University, 1985. https://digital.library.unt.edu/ark:/67531/metadc330997/.

Full text

Abstract:

This study utilized ethnographic methodology to describe the communicative interactional patterns in families with a member who has breast cancer. Three breast cancer patients whose families were between the adolescent and launching of children developmental lifestage (McGoldrick & Carter, 1982) were chosen for the study. Data were collected from a series of three interview sessions over a period of four weeks with a two week time lapse between each of the interview sessions. Interview sessions were conducted in the families' homes by the researcher. All interviews were video and audio tape recorded for the purpose of preserving data for transcribing and coding. Research questions examined individual perception of meaning in regard to the disease, the structure and organization of the family in relation to the illness, and the effects of family communicative interaction on the course and management of the disease. Findings indicated that family members' responses to the diagnosis of "breast cancer were influenced by multi-generational "beliefs. All three families formulated a collective belief which supported the mother's belief about the disease. Each of the three families were mother-centered, and each mother seemed to use a metacommunicative approach to mediating family transactions. Each of the three fathers were reported as having been isolated and withdrawn within the family at various times. However, each father appeared to play a protective role in deflecting tension and stress away from the mother. All three couples appeared to have constructed an egalitarian relationship with an implicit agreement as to who was more skilled to hold the power within a particular context. In all three families, the generational boundaries were clearly defined. Conflict and affect were most generally expressed in an indirect manner through wit and sarcasm. However, because each of these three families were structured to allow for personal autonomous functioning of each individual member, patients were supported in seeking a modality outside of the family system to express more ambivalent feelings.

APA, Harvard, Vancouver, ISO, and other styles

14

Hadjisavvas, Andreas. "BRCA1, BRCA2 molecular study of Cypriot breast cancer patients." Thesis, Brunel University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250211.

Full text

APA, Harvard, Vancouver, ISO, and other styles

15

Poon, Yuet-fai Helena. "The psychological reactions of breast cancer patients with mastectomy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B29697475.

Full text

APA, Harvard, Vancouver, ISO, and other styles

16

Shaw, Clare Elizabeth. "Diet, body weight and lymphodoema in breast cancer patients." Thesis, King's College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402098.

Full text

APA, Harvard, Vancouver, ISO, and other styles

17

Tahir, Mohammad. "Optimising the management of breast cancer in older patients." Thesis, University of Leicester, 2014. http://hdl.handle.net/2381/28827.

Full text

Abstract:

This study aimed to optimise the treatment of early breast cancer in older patients. It tested the hypothesis that comprehensive geriatric assessment (CGA) could be used to predict two-year survival in older breast cancer patients. Based on the CGA scoring a treatment algorithm was devised that could help in recommending whether primary endocrine treatment (PET) or surgery plus endocrine treatment would be best indicated in individual patients. Methods: The study included women >70 years of age with early breast cancer, seen in a dedicated Leicester clinic between 01/2005 and 04/2007. All patients had comprehensive assessment including documentation of Satariano Index of Co-morbidities (SIC), Mini-Mental State Examination (MMSE), Geriatric Depression Score (GDS), Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL) and American Society of Anaesthesiologists (ASA) grade. Logistic regression analysis explored any association between these components and two-year survival. Components with positive association were formulated into a Breast Cancer in Elderly Treatment Algorithm (BCETA). Results: 123 patients were included, age range 70-94 (median-82). Twenty-two patients died within two years. Logistic regression analysis found MMSE, ADL, and ASA score to have an independent association with two-year survival. The scores of these components were formulated into a BCETA. Logistic regression revealed a statistically significant association between the BCETA score and two-year survival (p-value 0.00). Other results for the BCETA prognostic model were: sensitivity 89%, specificity 46%, positive predictive value 87%, negative predictive value 52%, odds ratio 7.1 (95% CI 2.5-20.2), and overall accuracy of 81%. C-statistic value (area under ROC curve) for the BCETA score was 0.70. Conclusion: Breast Cancer in Elderly Treatment Algorithm is a new approach to optimise the management of breast cancer in elderly patients. It can help in identifying high-risk patients with expected short-survival who may benefit from PET, if their cancer is hormone receptor positive. Patients with predicted longer life expectancy (lowrisk) may be recommended standard treatment. Further studies are needed to validate it in a larger population.

APA, Harvard, Vancouver, ISO, and other styles

18

Cheng, Wing-ming Edward, and 鄭永明. "Emotional well-being in Chinese lung cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B3197157X.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Swartz, Esti. "Emotional intelligence and locus of control of adult breast cancer patients receiving treatment." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/d1015686.

Full text

Abstract:

Breast cancer is the most prevalent cancer of women in South Africa, with one in twenty-seven women diagnosed with breast cancer in their lifetime. By building on human strengths, ways can be found to cope effectively with adversity. This will contribute to psychological well-being and result in living constructive and meaningful lives. Emotional intelligence and locus of control are two constructs which, according to previous research, may be associated with psychological wellbeing. Limited research has been conducted on these constructs in populations facing adversity. Adaptation to breast cancer treatment is considered to be an extremely difficult process. The research aimed to explore and describe emotional intelligence and locus of control within an adult breast cancer population. A sample of 67 breast cancer patients receiving treatment was approached to complete a biographical questionnaire and two pencil-and-paper questionnaires. Descriptive and inferential statistics were be used to analyze the data. The results of the quantitative analysis indicated a significant negative correlation between emotional intelligence and locus of control which shows that patients with higher levels of emotional intelligence possess more internal locus of control orientations, while patients with lower emotional intelligence possess more external locus of control orientations. The population presented with above average emotional intelligence and an internal locus of control orientation. The study can be regarded as the first step in opening a field of research which could contribute to more effective coping and the overall psychological well-being of individuals facing adversity in South Africa. Furthermore, the findings of the study contributed to understanding the role of emotional intelligence and locus of control in these populations and encouraged further research and the development and implementation of programmes that promote skills development in these areas.

APA, Harvard, Vancouver, ISO, and other styles

20

Zucchero, Renee A. "Marital adjustment of older adult couples with breast cancer, prostate cancer, and couples without cancer." Virtual Press, 1998. http://liblink.bsu.edu/uhtbin/catkey/1117099.

Full text

Abstract:

The purpose of this study was to explore the marital adjustment of older adult couples with breast cancer, prostate cancer, and couples who have experienced neither. Participants were 64 couples in which at least one of the spouses was over 55 years of age, including 19 breast cancer couples, 20 prostate cancer couples, 25 couples who had experienced neither of these cancers. Most participants were young-old, Protestant, Caucasians from a high socioeconomic class. The breast cancer and prostate cancer participants had completed treatment an average of 39.5 months prior to participation. The methodology was a mail survey. Participants completed a demographic questionnaire, the Marital Satisfaction Questionnaire for Older Adults (MSQFOP) (Haynes et al., 1992), Primary Communication Inventory (PCI) (Navran, 1967), Miller Social Intimacy Scale (MSIS) (Miller & Lefcourt, 1982), and the Index of Sexual Satisfaction (ISS) (Hudson et al., 1981).There were no differences in the amount of discordance between the couples groups' level of marital satisfaction, communication, intimacy, and sexual satisfaction. In addition, there were no differences in the level of marital satisfaction, communication, intimacy, and sexual satisfaction between the participant groups. There was a significantly greater correlation between the prostate cancer couples' scores on the ISS than the correlation between the breast cancer couples' scores and the scores of the couples who had not experienced breast cancer or prostate cancer.The level of marital satisfaction, communication, intimacy, and sexual satisfaction reported was similar to that of the normative samples. There was no difference between the marital adjustment of the cancer couples and older couples who had experienced neither type of cancer. These results are good news for breast and prostate cancer survivors, and professionals. Older adults may be better able to incorporate the experience of cancer into their lives or are better prepared for chronic illness through anticipatory socialization. The high degree of agreement between the prostate cancer spouses on the ISS may be related to the sexual dysfunction that frequently accompanies treatment for this cancer. Future research should be qualitative and longitudinal and continue to explore the psychosocial implications of prostate cancer.
Center for Gerontology

APA, Harvard, Vancouver, ISO, and other styles

21

Hauser, Robert Sean. "Utilities of metastatic breast cancer patients treated with taxanes compared to utilities of oncology nurses." Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3035947.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Hackman, Marcia. "Coping strategies of women with breast cancer." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276869.

Full text

Abstract:

An ethnographic study was utilized to identify coping strategies of women with breast cancer. Five women were interviewed; four were interviewed on three separate occasions, and one was interviewed twice. The data were analyzed for specific coping strategies taken by the women to deal with the stresses of breast cancer. These strategies were compared and organized into categories of coping strategies: Actions Taken, Emotional Support, Positive Outcomes, Getting Control, and Keeping a Positive Attitude. These five categories were integrated as new coping incidents appeared in the data. The original five categories were merged into three categories: Getting Control, Compensating, and Emotional Support. From these three categories the theory was written: Women with breast cancer will obtain support, get control over what they can control, and compensate for what they cannot control.

APA, Harvard, Vancouver, ISO, and other styles

23

Göthlin, Eremo Anna. "Biological profiles of endocrine breast cancer." Doctoral thesis, Örebro universitet, Institutionen för hälsovetenskap och medicin, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-43963.

Full text

Abstract:

Funding: Magnus Bergvall Cancer Foundation; Percy Falk foundation for research in breast and prostate cancer; Nyckelfonden; Örebro University Hospital; Lions cancer research foundation, Region Uppsala-Örebro

APA, Harvard, Vancouver, ISO, and other styles

24

Lo, Hau-yan Phyllis. "Understanding breast cancer patients a 3-year follow-up study on psychosocial support groups /." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42182189.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Fertsch, Sonia Maria [Verfasser], and Christoph [Akademischer Betreuer] Andree. "Cancer recurrence risk after lipofilling in breast cancer patients with DIEP flap reconstruction." Freiburg : Universität, 2016. http://d-nb.info/1122743343/34.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Möller, Ernst Lodewicus. "Patient reported outcome measures (PROMs) in breast cancer patients after immediate breast reconstruction using the Breast-Q." Master's thesis, Faculty of Health Sciences, 2021. http://hdl.handle.net/11427/32865.

Full text

Abstract:

Background Mastectomy is the mainstay of surgical treatment for women with breast cancer in South Africa. The increase in breast reconstruction after a mastectomy has prompted the need to evaluate patient reported outcome measures (PROMs) for this set of operative intervention. This study aimed to assess clinical and patient reported outcome measures in immediate breast reconstruction patients using the BREAST-Q and compare these with international cohorts. Methods A cross-sectional study was performed on all patients who underwent immediate breast reconstruction between January 2011 and December 2016. This consisted of a retrospective clinical record review of perioperative outcomes, and a quality of life analysis using the BREAST-Q Post-Reconstruction questionnaire. Outcome predictors were identified using Chi-square, Fisher exact, One-way ANOVA, Student t-tests and Kruskal Wallis analysis of variance. A random-effect single arm meta-analysis was performed to compare the BREASTQ scores with international cohorts. Results A total of 52 patients were included with a mean age of 43.2 (+/-9.5) years. Eighteen patients (34.6%) developed early complications; of these 8 (44.4%) were major. Thirty-one patients (59.6%) developed late complications; of these 18 (58.1%) were major. Fifteen patients (28.8%) had failed reconstruction. There was a significantly higher risk of failure following a total mastectomy (TM) (p=0.02), tissue expander reconstruction (TE) (p< 0.01) and stage 2 breast cancer (p=0.01). Patients who underwent nipple reconstruction and immediate-delayed reconstruction before 12 months, reported higher well-being and satisfaction scores. Compared to international cohorts our BREAST-Q scores were lower but fall within the 95% confidence interval for Sexual Well-Being and Satisfaction with Nipples and Care. Conclusion Immediate breast reconstruction poses a high risk of complications and reconstructive failure especially, with TM and TE. Our BREAST-Q scores are comparable to international studies and may be useful in guiding patient consent.

APA, Harvard, Vancouver, ISO, and other styles

27

Yuen, Hang-yuk. "A study of sexual dysfunction in female breast cancer patients /." Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19470794.

Full text

APA, Harvard, Vancouver, ISO, and other styles

28

Ramroth, Johanna Rankin. "Radiotherapy dose-fractionations and outcomes in cancer patients." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:8c5a99de-7d8c-4b19-9a91-e6cf4efa7bd2.

Full text

Abstract:

Radiotherapy cures many cancers, but the optimum total doses and fractionations used to treat different cancer types remain uncertain. While conventional fractionation (≈2 Gy per fraction) is common in many countries, UK practice has been highly variable. This thesis compared different curative-intent radiotherapy dose-fractionations used in non-small cell lung and breast cancer. These two cancers together make up over a quarter of UK cancer incidence and mortality, and radiotherapy can increase cure rates of both cancers. Two studies were conducted: (A) A meta-analysis of randomised radiotherapy trials in non-small cell lung cancer and (B) A cohort study of non-small cell lung and breast cancer radiotherapy in the Thames Valley. For the meta-analysis, a systematic search was conducted. Eligible studies were randomised comparisons of two or more radiotherapy regimens. Median survival ratios were calculated for each comparison and pooled. 3,795 patients in 25 randomised comparisons of radiotherapy dose were studied. When radiotherapy was given alone, the higher dose within-trial resulted in increased survival (median survival ratio 1.13, 95% confidence interval 1.04-1.22). When radiotherapy was given with concurrent chemotherapy, the higher dose within-trial resulted in decreased survival (median survival ratio 0.83, 95% confidence interval 0.71-0.97). For the cohort study, multiple Public Health England data sources were combined to obtain information on radiotherapy, patient characteristics, and outcomes. Multivariable Cox regressions were conducted separately by cancer site. 324 non-small cell lung, 8,879 invasive breast, and 477 ductal carcinoma in situ patients were studied. In analyses of both non-small cell lung and invasive breast cancer, increasing radiotherapy dose was associated with improved survival in some treatment centres, while in other centres the opposite was true. These opposite trends by treatment centre were unlikely to be explained by chance, and they suggest that differences in patient selection were driving results. There were insufficient events among ductal carcinoma in situ patients to assess associations. Findings from the meta-analysis support consideration of further radiotherapy dose escalation trials, making use of modern methods to reduce toxicity. Findings from the cohort study suggest that it is not possible to use observational studies to examine causal effects of radiotherapy dose-fractionation. This thesis therefore shows the continued importance of conducting sufficiently large randomised trials to ascertain optimal dose-fractionation in radiotherapy.

APA, Harvard, Vancouver, ISO, and other styles

29

Wilczek, Brigitte. "Application of nuclear medicine methods in patients with breast cancer /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-340-X/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Soerjomataram, Isabelle. "Multiple primary cancers in patients with breast ans skin cancer." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/10779.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Teh, Li Ling Grace. "Psychological and biochemical parameters of stress in breast cancer patients /." Adelaide, 1997. http://web4.library.adelaide.edu.au/theses/09ARPS/09arpst261.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Taylor, Kimberly. "Fertility education needs and disparities in female breast cancer patients." Connect to resource, 2008. http://hdl.handle.net/1811/32238.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Brennan, Sarah Frances Mary. "Diet, lifestyle and quality of life in breast cancer patients." Thesis, Queen's University Belfast, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579612.

Full text

Abstract:

Despite much research investigating the role of diet and lifestyle in breast cancer, the evidence for many dietary factors remains uncertain. The main focus of this thesis concerns the role of dietary patterns and fat in breast cancer risk and also recurrence and survival in breast cancer patients. Meta-analyses conducted in this thesis have suggested that a prudent dietary pattern may reduce the risk of breast cancer, whilst a drinker dietary pattern may increase risk. High saturated fat intake was also found to be associated with breast cancer mortality. Data obtained from participants of the DietCompLyf study, a prospective cohort of breast cancer patients in the UK, was used in this thesis to investigate dietary patterns and fat intake in relation to breast cancer recurrence and quality of life. The physical activity questionnaire used in the DietCompLyf study was also retrospectively validated in this thesis to determine how best to use the physical activity information as a confounder in the" diet and breast cancer recurrence and quality of life analyses in this thesis. In participants of the DietCompLyf study, adherence to a Traditional dietary pattern was associated with an increased risk of breast cancer recurrence. A prudent dietary pattern was associated with a better quality of life, whilst Western dietary patterns associated with a poorer quality of life in unadjusted analyses. The complicated nature of the diet and quality of life relationship was highlighted when adjustment for potential confounders modified and attenuated the observed associations. Results observed in this thesis suggest possible roles for diet in both risk of breast cancer and breast cancer mortality. Further analyses of data obtained from the DietCompLyf cohort should be conducted in the future to clarify theses observations.

APA, Harvard, Vancouver, ISO, and other styles

34

Brazil, Lucy Caroline Alexandra. "Gene Expression in High-risk Breast and Ovarian Cancer Patients." Thesis, Institute of Cancer Research (University Of London), 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.504783.

Full text

Abstract:

Germline mutations in human BRCA 1 and BRCA2 genes confer a lifetime risk of breast cancer of between 60 and 85% and a lifetime risk of ovarian cancer of between 15 and 40%. Identification of mutations in these genes either in healthy carriers or in those who have already developed cancer is important for clinical management, including prophylactic measures to reduce the risk of disease. BRCA 1 and BRCA2 were identified more than 10 years ago, but due to a number of features such as large gene size and heterogeneity of mutations, genetic testing of BRCA is both labour intensive and often inconclusive. The aim of this project is to find a characteristic phenotype that is indicative of BRCA heterozygosity in individuals without clinical signs of disease. This could be used as a functional preliminary screen for these high-risk patients. Previous studies have illustrated the differences in gene expression profiles between 'normal' and BReA derived tumours. Studies using chicken DT 40 cell lines have shown that a Brca2 heterozygote phenotype exil:?ts but, this is as yet to be conClusively demonstrated in humans. . In this study, gene expression profiles, from 'healthy' patients who are heterozygous for BRCA have been analysed using data from microarrays. RNA was prepared from immortalized Epstein-Barr virus transformed human lymphocyte (EBVTL) cell lines, taken from normal controls and carriers for BRCA 1 and BRCA2 mutations. Gene expression profiies were also assessed before and after exposure to DNA damaging agents.

APA, Harvard, Vancouver, ISO, and other styles

35

Yuen, Hang-yuk, and 袁亨玉. "A study of sexual dysfunction in female breast cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B31250336.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Kanatas, Anastasios. "Development of a breast cancer specific patients concerns inventory (PCI)." Thesis, University of Liverpool, 2013. http://livrepository.liverpool.ac.uk/13339/.

Full text

Abstract:

Introduction: Treating breast cancer is based on a combination of therapies: surgery, radiotherapy, chemotherapy, as well as hormonal and biological agents. The full impact of the disease and its treatment at a human level is often underestimated, and the benefits of holistic cancer care are increasingly recognised. Furthermore, patients often face a frightening and uncertain journey that presents a variety of needs. Moreover, recovery is not necessarily the end-point of the cancer experience. The many complexities and challenges in the identification of patient issues along this journey can lead to unmet needs. This can be particularly difficult in the confines of a busy clinic, where time constraints, together with an over-reliance on verbal communication, can pose significant barriers to effective consultations. A novel tool, known as the patient concerns inventory (PCI), has been successfully developed and introduced for use in patients with head and neck cancer. In this setting, it has helped to formulate an individualized record of patient concerns, needs, and priorities, thereby structuring outpatient consultations, and promoting and facilitating a multidisciplinary approach. This study aimed to develop and assess a PCI specific to breast cancer and to evaluate its impact on patient care; that is, to provide a “proof of concept” for a breast cancer PCI. Methods: This was a four-phase study, as follows. (1) Item generation through a literature review, input from clinicians (n = 10), four patient focus groups (n = 24), and national breast cancer charities (n = 3). (2) A survey of breast cancer patients (n = 200) for cross-sectional validation, to compare the PCI with an established quality of life tool and to look at the relative frequency of items and any associations. (3) A pilot, before and after study, assessing the PCI in a clinical setting with breast cancer patients (n = 53). (4) Semi-structured interviews with a breast surgeon (n = 1) and specialist nurses (n = 2) who used the PCI during clinics, to identify the perceived benefits of using the PCI. Results: In total 277 patients responded and participated in this work. The literature review identified 164 items; following input from clinicians, focus groups, and national charities, 56 items remained. The cross sectional study (phase 2; n=200, 80 % response rate) revealed that patients wanted to discuss the following: breast sensitivity or pain (46 %), fatigue (46 %), hot flushes (44 %), sleep (34 %); breast appearance (30 %), unable to control weight (28 %), mastectomy appearance (19 %), overall physical appearance (17 %); fear of recurrence (62 %), fear of cancer spreading (39 %), fear about the future (32 %), or one or more of these (72 %); ‘mood’ (15 %), ‘anxiety’ (21 %), ‘depression’ (17 %), or one or more of these (35 %); Phase 3 found that the PCI resulted in a focused consultation and no increase in consultation time. All the patients from phase 3 wanted to see a breast surgeon. Phase 4 revealed that clinicians involved with the PCI supported its use, and stated several advantages. In its final format, the breast cancer specific PCI had 57 items over several domains, with 16 referral options. Conclusions: The PCI could identify issues that patients would like to discuss in the breast oncology clinic. The routine use of the PCI in follow-up clinics could ultimately improve care for women with breast cancer; however, the clinical environment continues to make it difficult to screen for issues related to intimacy, relationship, and sex. Further research is essential to evaluate the breast cancer specific PCI. A larger patient cohort, a longitudinal approach, qualitative input, and a link to possible interventions, would each improve our understanding of the issues faced by breast cancer patients.

APA, Harvard, Vancouver, ISO, and other styles

37

Yeung, Shuk-chong Rene, and 楊淑莊. "Self-evaluation of coping resources of cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31250750.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Ho, Tin-hung Rainbow. "Psychophysiological effects of psychosocial interventions : an example of breast cancer patients in Hong Kong." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31049060.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Chan, Yu. "An exploratory study on spiritually and psychosocial well-being in chinese breast cancer patients." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40887832.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Walsh, Dicks Elizabeth L. "Surgery for breast cancer in St. John's : the statistics, the surgeons' view, the patients' view /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0032/MQ47486.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Chan, Wing-chiu Michelle. "Relationships between attentional bias, posttraumatic growth, and psychopathology in breast cancer patients." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41712614.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Brand, Juanita M. "The lived experiences of six women during adjuvant chemotherapy for Stage I or II breast cancer." Virtual Press, 2005. http://liblink.bsu.edu/uhtbin/catkey/1317926.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Kirshbaum, Marilyn. "Disseminating research evidence to breast care nurses : the case of exercise for breast cancer patients." Thesis, University of Manchester, 2004. http://eprints.hud.ac.uk/10717/.

Full text

Abstract:

Background: Historically, nursing has struggled to introduce researchbased interventions into routine clinical practice. Reasons for this difficulty range from poor communication between clinically and academically based nurses to limitations within organisations that obstruct the implementation of new ideas. Aims: To identify the barriers to research utilisation and the preferred methods of research dissemination amongst breast care nurses (BCNs), to develop a dissemination intervention for BCNs and to evaluate a dissemination intervention for BCNs. Method: The study was conducted in three stages. In Stage 1, a national survey was conducted using the Barriers to Research Utilisation Scale (Funk et al. 1991), questions about dissemination preferences and a demographic questionnaire. In Stage 2, the Conceptual Framework for Selecting a Targeted Experimental Dissemination Method based on social interactionalist theory was developed. In Stage 3, a pre-test/post-test randomised controlled design was used to evaluate the dissemination method developed in Stage 2; the unit of randomisation and analysis were hospital clusters of BCNs. Sample: 263 BCNs from 13 regions within the U.K. comprised the sample in Stage 1. In Stage 3, the sample consisted of 92 BCNs from 62 hospitals in the north of England. Analysis: In Stage 1 analysis was undertaken using descriptive and nonparametric statistics. In Stage 3, analysis consisted of descriptive statistics 19 and clustered regression techniques with estimation of robust standard errors: clustered logistic regression for knowledge items, clustered linear regression for knowledge scores, ologit for attitude and reported practice items and clustered multiple regression for paired and multiple variable analyses. Findings: The results from the Barriers Scale revealed ‘statistical analyses not understandable’, ‘insufficient time on the job to implement new ideas’, ‘facilities inadequate for implementation’, ‘research not reported clearly and readably’ and ‘no time to read research’ as the greatest barriers to research utilisation. Free text responses revealed additional problems with communication and conditions within provider organisations and identified facilitators for research utilisation and dissemination. These data led to the selection and production of a targeted information booklet, entitled Exercise and Breast Cancer: A Booklet for Breast Care Nurses, specifically designed to be accessible, time efficient, understandable and relevant to the target audience. In evaluation, the booklet was shown to overcome the perceived barriers of the sample associated with accessing and understanding research. A statistically significant increase in knowledge and changes of reported practice and attitudes were found. Robust variables affecting knowledge acquisition were identified as the promotion of health, promotion of exercise and understanding of how exercise can reduce cancer-related fatigue. Implications: This study has demonstrated that printed materials can be used as an effective dissemination method provided that they are developed in line with the needs, values and context of a target audience. The 20 Conceptual Framework can be followed to develop similar booklets on different topics and could provide a purposeful contribution to the promotion of evidence-based practice for all nurses.

APA, Harvard, Vancouver, ISO, and other styles

44

Daniels, Danielle-Kirsty. "Exploring the experiences of patients with breast cancer from diagnosis through management." Thesis, University of the Western Cape, 2011. http://hdl.handle.net/11394/3955.

Full text

Abstract:

Magister Artium (Psychology) - MA(Psych)
The aim of this study is to explore the role of communication between the physician and women with breast cancer, and to examine women’s coping mechanisms from diagnosis through the management of the illness to its resolution. A qualitative methodology was utilised, with purposive sampling of participants from a public hospital in the Western Cape. A semi-structured interview was used to gather the data, after which a thematic analysis was conducted. The findings reveal the information exchange between physician and patient was clear, direct and understandable. Furthermore, the participants coped by accessing and using support from family and friends, by recourse to spirituality and prayer (bargaining with God, questioning of God), and by developing a positive attitude, with hope for recovery and acceptance. There were also emotional and psychological reactions from women in the sample when they received their diagnoses. This study may provide valuable insights into the experiences of women with stages I to III of breast cancer

APA, Harvard, Vancouver, ISO, and other styles

45

Jacobs, Christine June. "Communication about genetic testing and hereditary cancer management with breast and ovarian cancer patients." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10046946/.

Full text

Abstract:

Background: Women with breast or ovarian cancer (patients) are increasingly offered genetic testing shortly after diagnosis to guide management and identify future cancer risks. As a result, new approaches to communication about hereditary cancer are needed to inform decision-making amongst patients and their relatives. Aims: This thesis aimed to investigate expert opinion and guideline recommendations about the communication needs of patients undergoing genetic testing, the information communicated by genetics health professionals and recalled by patients and their relatives and the experience of patients with newly diagnosed breast cancer who undergo genetic testing. Methods: A scoping review and five studies were conducted using UK data from patients and health professionals: an observational study, a Delphi survey, a content analysis, a document analysis and mixed methods matrix and a qualitative study. Results: Accuracy of information recall was low amongst patients and relatives following genetic counselling, especially about hereditary cancer management. Expert health professionals and service users agreed on the key messages required by patients to inform decision-making for themselves and their relatives. However, during genetic counselling, half of the key messages were communicated to patients and fewer key messages were communicated about hereditary cancer management than genetic testing. Recommended information to communicate to patients was identified from international genetics guidelines. Recommendations about hereditary cancer management were infrequently reflected in expert opinion, communicated by genetics health professionals or recalled by patients. Newly diagnosed patients experienced growing uncertainty and concern about inheritance and surgical decision-making, especially when their genetic test result was unexpected. Conclusions: Patients received insufficient information to understand their future cancer risks and make informed decisions about managing hereditary cancer. Steps are needed to improve information provision, especially when results are unexpected. These findings can help guide refinements to communication as genetic testing is integrated into mainstream oncology.

APA, Harvard, Vancouver, ISO, and other styles

46

Thornton, Lisa Marie. "Stress and immunity in a longitudinal study of breast cancer patients." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1117578022.

Full text

APA, Harvard, Vancouver, ISO, and other styles

47

Oh, Daniel S. Perou Charles M. "Prediction of outcome in breast cancer patients using gene expression profiling." Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2006. http://dc.lib.unc.edu/u?/etd,501.

Full text

Abstract:

Thesis (Ph. D.)--University of North Carolina at Chapel Hill, 2006.
Title from electronic title page (viewed Oct. 10, 2007). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Curriculum in Genetics and Molecular Biology." Discipline: Genetics and Molecular Biology; Department/School: Medicine.

APA, Harvard, Vancouver, ISO, and other styles

48

Prochazka, Michaela. "The risk of second primary lung carcinoma in breast cancer patients /." Stockholm, 2006. http://diss.kib.ki.se/2006/91-7140-649-2/.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Wagner, Gina Marie. "Exploring breast cancer memoir." 2008. http://0-proquest.umi.com/pqdweb?did=1597602761&sid=2&Fmt=2&clientId=14215&RQT=309&VName=PQD.

Full text

Abstract:

Thesis (Ph.D.)--University of Nebraska-Lincoln, 2008.
Title from title screen (site viewed Feb. 17, 2009). PDF text: iv, 173 p. ; 687 K. UMI publication number: AAT 3325857. Includes bibliographical references. Also available in microfilm and microfiche formats.

APA, Harvard, Vancouver, ISO, and other styles

50

Cardoso, Raquel Alexandra Lobo. "Neoadjuvant endocrine therapy in breast cancer patients." Master's thesis, 2016. https://repositorio-aberto.up.pt/handle/10216/89307.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!