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Radcliffe-Branch, Deborah S. "The contribution of interactive health communication (IHC) and constructed meaning to psychosocial adjustment among women newly diagnosed with breast cancer /." Thesis, McGill University, 2005. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=85956.
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This doctoral dissertation, as part of a large and ongoing CIHR-funded study, used a subset of the total sample to evaluate the contribution of interactive health communication (IHC) as a complement to more traditional means of informational support (Care-as-usual) to optimal adjustment of women newly diagnosed with breast cancer (N = 135). According to the study protocol, participants in the experimental group received an IHC educational intervention for an eight-week period. Measures of psychosocial adjustment and information-related variables were administered in interviews at Time 1 (pre-intervention) within 8 weeks of initial diagnosis, and again 8 weeks post-intervention (Time 2). Psychosocial adjustment variables included: depressive symptoms (CESD), anxiety (STAI-Y), well-being (IWB), and quality of life (SF-36)-mental and physical health components. Information-related variables included: the need for information related to cancer, cancer-specialist, and family or friend's informational support, and overall satisfaction with information. Optimism and Constructed meaning were evaluated at Time 1 and 2, respectively. A GLM MANCOVA model tested overall F-ratios and regression coefficients using difference scores. Predictors in the model were: group (experimental versus control), constructed meaning, and optimism. The overall model (df = 8, 121) was significant for Group, F = 3.66, p < .001, effect size eta2 = .20, Constructed Meaning, F = 3.04, p < .004, effect size eta2 = .17, and Optimism, F = 2.95, p < .005, effect size eta2 = .16. Participants in the dissertation experimental group had significant improvements in QOL-physical health and overall satisfaction with information when compared with the control group. Constructed meaning was significantly associated with beneficial changes in all of the adjustment-related variables. The results of this dissertation clarify the potentially significant roles IHC and constructed meaning pl
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Kyei, Kofi Adesi. "Assessment of Anxiety and Depression Among Breast Cancer Patients Undergoing Treatment in Ghana." ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/4526.
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Breast cancer patients undergoing radiotherapy often experience severe levels of anxiety and depression. There is a gap in the research literature from Africa, particularly from Ghana, with few studies focusing on the assessment of anxiety and depression among breast cancer patients undergoing radiation treatment. A better understanding was essential to promote efforts to help breast cancer patients cope with their diagnosis and treatment and increase their overall quality of life. This mixed method study examined breast cancer patients in Ghana undergoing radiotherapy and their responses related to anxiety and depression through a concurrent triangulation involving an interview with selected professional participants and a detailed patient survey. Patients completed 2 modified scales, the Patient Health Questionnaire and Depression Anxiety Stress Scale. The sample consisted of 100 patients between the ages of 20-89. Individual interviews were held with 6 professionals with a minimum of 5 years of work experience. Themes were generated through open coding of the interview data, while multiple regression was performed to determine the relationship between depression and anxiety with the independent variables . Findings of this study indicated the need intervene through counseling and education on behalf of patients in Ghana as they undergo breast cancer treatment. Age and monthly income of patients were statistically significant in predicting the anxiety and depression among the patients. The study's implications will lead to positive change when all stakeholders take on the responsibility of implementing measures to promote coping strategies for breast cancer patients in Ghana.
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Ferlatte, Christy. "Patient preferences for an appropriate time for cancer genetic counseling and BRCA testing for women diagnosed with breast cancer." Waltham, Mass. : Brandeis University, 2009. http://dcoll.brandeis.edu/handle/10192/23193.
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Coltri, Julia Anne. "Transgender male patients and hereditary breast cancer risk: broaching difficult topics to reduce healthcare disparities." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555683611281611.
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Alsulaiman, Reem Jawad. "Exploring women's experiences with breast cancer and the effectiveness of psychotherapeutic interventions in relation to mental wellbeing and treatment compliance in patients residing in the state of Qatar." Thesis, Regent's University London, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738185.
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Introduction: An insufficient number of studies have been carried out in the Middle East exploring the variables that contribute to breast cancer patients’ psychological distress. In addition, very few studies exist that evaluate the role of structured psychotherapeutic interventions in enhancing breast cancer patients’ psychological well-being and quality of life. This study has been designed to address this limitation by conducting a mixed-method approach to explore women’s experiences with the diagnosis of breast cancer and with two structured psychotherapeutic interventions, namely, ‘crisis counselling’ and ‘psycho-education’. Methods: A total of 201 women with early stage breast cancer from the State of Qatar were recruited and randomised into either the control group or one of the treatment groups (crisis counselling and psycho-education). The aim of the quantitative approach was to evaluate the short- and long-term benefits of the crisis counselling and psycho-education interventions, in terms of improving patients’ psychological well-being, quality of life and treatment compliance. This was achieved by asking all patients to complete the DASS21 and QLQ-C30 instruments at different points in time and by monitoring their compliance with treatment. Later, a qualitative approach was utilised: twelve Arab patients from the treatment groups were invited to attend focus-group interviews in order to explore their experience with the diagnosis of breast cancer and with the study interventions. Results: the qualitative results of this study revealed that fear of social stigma, difficulty coping with fatigue and body image changes, and altered intrafamilial/sexual relationships contribute significantly to Arab women’s psychological distress. The quantitative results revealed that both of the study interventions were effective in improving women’s psychological well-being and quality of life over time but had no impact on patients’ compliance with treatment. In addition, the study showed that psycho-education conferred a greater advantage than did the crisis counselling model, especially on improving women’s psychological well-being over time. Conclusion: The results of this study will significantly aid health care professionals in the State of Qatar to improve the care of breast cancer patients, through awareness-raising education about the disease and its associated social stigma and by initiating changes to the psychotherapeutic services through the implementation of crisis counselling and psycho-education interventions in the future.
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Grobbelaar, Frederik Russouw. "Die invloed van 'n mastektomie op die man-vrou verhouding : 'n pastorale ondersoek." Thesis, Stellenbosch : Stellenbosch University, 1993. http://hdl.handle.net/10019.1/19405.
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Thesis (MTh)--Stellenbosch University, 1993ENGLISH ABSTRACT: Seeing that breast cancer is the most common cancer in women and that it has such a high incidence that every woman should be aware of it, time has come for the theology, and especially for pastoral care, to provide some answers on the possible problems that accompany the illness. Treatment of breast cancer almost always include a degree of surgical intervention through which part of or a whole breast, and in extreme cases even the underlying tissue, is being removed. This procedure, to some extent, influences a woman's experience of her physique which in turn has an effect on the intimate space of her marriage. The mastectomy patient may experience that the operation, with all the psychological affects it has, disturbs her inner life rythm and that results in her relationships also being pressurised. The crisis of a mastectomy should be handled as a relationship crisis within a marriage, in which the husband can play an important therapeutic role. The husbands contribution will be greatly effected by: a) His commitment to the relationship and b) The correlation between his male identity, his sexuality and his perceptions of the female physique. Within the crisis of mastectomy, the woman's body-image should not be separated from her faith identity and the quality of her marriage - there exists a dynamic interaction between these three, which means that the handling of the crisis of a mastectomy is directly dependent on the quality if her loving relationship and on the way in which she experiences her faith. The faith factor plays an important role in the handling of the crisis, by creating a distance between the trauma of the loss and the way in which she experiences her identity. Pastoral care can play a vital role in the handling of the crisis of a mastectomy by means of guidance and support, as it proclaims the active presence of God through the marrid body of Jesus Christ. The husband of the mastectomy patient can, in his therapeutic role, be guided to be much more sensitive for the emotional needs of his wife, in regard to aspect of sexuality. This would give her the support she needs and work constructively towards the goal of healing.
AFRIKAANSE OPSOMMING: Aangesien borskanker die algemeenste kanker onder vroue is en dit sulke geweldige afmetings aangeneem het dat elke vrou daarmee moet rekening hou, het dit tyd geword dat die teologie, en met name die pastoraat, ditself ook ten opsigte van die moontlike problematiek wat daarmee saamgaan, moet verantwoord. Die behandeling van borskanker behels in die meerderheid van gevalle 'n mate van chirurgiese ingrepe waardeur 'n deel van of die hele bors, en in ekstreme gevalle ook die onderliggende weefsel, verwyder word. Hierdie prosedure oefen, in 'n mindere of meerdere mate, 'n invloed op die vrou se belewing van haar liggaamlikheid uit wat weer na die intieme band van die huwelik kan deurwerk. Die mastektomiepasiënt kan ervaar dat die operasie, met al die sielkundige effekte wat dit inhou, haar innerlike lewensritme versteur sodat die verhoudinge waarin sy leef ook onder druk geplaas word. Binne die huwelik sou 'n mens dan die krisis van 'n mastektomie as 'n verhoudingskrisis moet hanteer, waarin die eggenoot 'n belangrike terapeutiese funksie kan vervul. Die man se bydrae word egter deurslaggewend bepaal deur: a) Sy verbintenis aan die verhouding en b) Die korrelasie tussen sy manlike identiteit, seksualiteit en die persepsies met betrekking tot die liggaamlikheid van die vrou. Binne die krisis van 'n mastektomie kan die vrou se liggaamsbeeld nie van haar geloofsidentiteit en die kwaliteit van haar huwelik losgemaak word nie - hierdie drie staan in 'n interdinamiese verband en beteken dat die verwerking van die krisis van 'n mastektomie direk van die kwaliteit van die liefdesverhouding en die ervaring van geloof, afhang. In die verwerking van die krisis vervul die geloofsfaktor 'n deurslaggewende rol om afstand tussen die emosionele trauma van die verlies en die ervaring van identiteit te skep. Die pastoraat kan 'n belangrike funksie vervul ten opsigte van begeleiding en ondersteuning in die verwerking van die krisis van 'n mastektomie deurdat dit God se aktiewe betrokkenheid by die situasie, aan die hand van die liggaamlikheid van Jesus Christus, verkondig. As terapeut kan die eggenoot begelei word om, op die gebied van die seksuele, baie sterker op die emosionele behoeftes van die mastektomiepasiënt ingestel te wees, om haar sodoende te ondersteun en in die proses van heling mee te werk.
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Dasch, Kimberly B. "Affective differentiation in breast cancer patients." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 70 p, 2009. http://proquest.umi.com/pqdweb?did=1885670961&sid=7&Fmt=2&clientId=8331&RQT=309&VName=PQD.
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Lagergren, Jakob. "Immediate breast reconstruction with implants in breast cancer patients /." Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-230-9/.
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Yeung, Shuk-chong Rene. "Self-evaluation of coping resources of cancer patients /." Hong Kong : University of Hong Kong, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B22330914.
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Cheng, Wing-ming Edward. "Emotional well-being in Chinese lung cancer patients." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B3197157X.
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Wolfman, Jessica Heather Kloss Jacqueline D. "Cancer specific stress and insomnia severity among breast cancer patients /." Philadelphia, Pa. : Drexel University, 2009. http://hdl.handle.net/1860/3024.
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Daniels, Tasneem. "Bi-rads final assessment categories in breast cancer patients." Thesis, Cape Peninsula University of Technology, 2019. http://hdl.handle.net/20.500.11838/2969.
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Thesis (MSc (Radiography))--Cape Peninsula University of Technology, 2019INTRODUCTION: The Breast Imaging Reporting and Data System (BI-RADS) was developed by the American College of Radiology (ACR). The BI-RADS is an internationally accepted method of assessing and reporting on mammograms and breast ultrasound images. The BI-RADS consists of a lexicon (descriptors) and assessment categories. The ACR aimed to standardise mammography reporting and placing the findings in the appropriate assessment category. The aim of this study was to establish the accuracy of the BI-RADS assessment categories for mammography and breast ultrasound images in women diagnosed with breast cancer. METHOD: Data were retrieved from 77 patients who were diagnosed with breast cancer from 1 January 2013 to 31 December 2014. Seven did not meet the inclusion criteria and were excluded. The study sample size was 70 (n=70) patients. All mammography reports included a BI-RADS assessment category of all patients diagnosed with breast cancer within the study period. These reports were analysed and compared with histopathology results. The BI-RADS assessment category and descriptors were collected from the mammogram reports; the histopathology report indicated the type of breast cancer. All reports were obtained from the patients' folders at the research site. In addition, questionnaires were distributed among radiologists to assess whether their experience and training had an influence on the accuracy of reporting in the BI-RADS assessment categories. Descriptive and inferential statistical analysis was used for data analysis. RESULTS: The most common malignancy diagnosed was invasive ductal carcinoma with a total of 70% (n=54), followed by ductal carcinoma in situ with 10.4% (n=8) and invasive lobular carcinoma with 9.1% (n=7). The histology results confirmed breast cancer for all BI-RADS 4 and 5 assessment categories. The mammogram was able to detect 93.5% of abnormalities and breast ultrasound 84.4% of abnormalities in this study sample. Breast ultrasound was used as an adjunct to mammography and hence an overall combined diagnostic rate was 100%. Mammography descriptors: The more common malignancy findings were spiculated mass margin, 35.1% (n=27). Ultrasound descriptors: The more common malignancy findings were hypoechoic echo pattern, 55.8% (n=43). There was no significant association (p=0.152) between the radiologists' years of experience and BI-RADS 3, 4 and 5 assessment category reporting. Of the 15 responses, 67% agreed that the BI-RADS standardises breast imaging reporting and reduces confusion, 33% agreed that the BI-RADS allows better communication between radiologists and referring physicians, and 40% agreed that the BI-RADS clarifies further management for patients by helping to stratify risk management. CONCLUSION: The outcome of this study indicated that the use of BI-RADS assessment categories is useful for predicting the likelihood of malignancy when used correctly. The outcome of BI-RADS 4 and BI-RADS 5 had a positive predictive value of 100%, which corresponded well with histology results. The descriptor findings suggested that spiculated mass margins, irregular-shaped masses, hypoechoic echo pattern and posterior shadowing were high predictors of malignancy and warranted a placement in the BI-RADS 5 assessment category.
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Alburai'Si, Kholoud Mubarak. "Stratification of breast cancer patients : a proteomic approach." Thesis, King's College London (University of London), 2016. https://kclpure.kcl.ac.uk/portal/en/theses/stratification-of-breast-cancer-patients(a8102723-9f21-4495-8401-d3e8ce503968).html.
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Breast cancer represents a heterogeneous collection of different diseases characterized by different pathological and biological features, clinical presentation, clinical behaviour, response to treatment and outcome. In current practice, pathological diagnosis and classification of breast cancer is based mainly on well-established traditional morphologic features. However, morphological features alone do not adequately reveal the molecular heterogeneity and complexity of breast cancer. Still, there are relatively few biomarkers widely used in prognostication in invasive breast cancer and in predicting response to targeted therapies, and even fewer of value in the clinical management of the pre-invasive disease of ductal carcinoma in situ (DCIS). There is therefore an unmet need for biomarkers for better classification, better prediction of prognosis and of prediction of response to therapy for both invasive breast carcinoma and DCIS. The co-expression of a HER2/HER3 combination results in more aggressive tumour growth and is associated with endocrine and chemotherapy resistance, driven not simply by receptor expression but also by signalling via the receptors dimers. Therefore, methods which directly query signalling pathway activation in breast cancer specimens are anticipated to provide important insights into the molecular ‘‘logic’’ that distinguishes cancer from normal tissues and potentially to have an important impact on personalized intervention strategies. The aim of this thesis has been directed at evaluating candidate biomarkers in breast cancer. This has been targeted at examining attributes associated with known functional properties of candidate drivers of disease or resistance to treatment rather than those traditionally based on altered expression of these biomarkers. Specifically, the work was directed at the HER1-3 members of the EGFR family of growth factor receptor in breast cancer. In this project I have in part developed, tested and evaluated two methods, which have the ability to detect protein-protein complexes at a single molecule level and thus allow the study of signalling pathways in situ. The first method is an in-house coincidence detection technology created from two recombinant fusion proteins and the second is a commercially available proximity ligation assay (PLA) method. Both approaches were able to detect the target proteins with high sensitivity and specificity, however the proximity ligation assay was subsequently used here to assess the protein complexes and activation status of the EGFR family in breast cancer patient’s samples. The patient study cohort is derived from a consecutive series of approximately 293 cases of primary operable invasive breast cancers obtained from the Guy’s and St Thomas (King’s Health Partner’s) Breast Cancer Biobank archive presenting between 1990 and 1992. In these cases, 9 different biomarkers were studied for HER family expression level, dimer expression and activation status using proximity ligation assays (PLAs). The relationship between HER activation status, dimer expression and relapse free survival (RFS) was investigated and stratified multivariate regression analysis identified factors influencing patient prognosis. In conclusion, PLA successfully and reproducibly detected HER protein complexes and phosphorylation in vivo. A significant association was identified between high levels of phosphorylated HER2 and reduced recurrence-free survival (RFS) in invasive lobular carcinoma (p = 0.04, HR 0.99, 95% CI: 0.997-1.002). High levels of HER1/HER3 dimers were associated with reduced RFS in T1 (<2cm) breast cancer patients, (p = 0.02, HR 1.84, 95% CI: 1.08-3.13). Similarly, high levels of HER1/HER3 and HER2/HER3 dimers were associated with reduced RFS in breast cancer patients with N1 nodal status (p <0.0001, HR 1.84, 95% CI: 0.58-1.93) and (p <0.0001, HR 0.64, 95% CI: 0.45-0.90) respectively). Work in this thesis demonstrates that in situ detection of HER protein complexes and activation status can be monitored robustly and with specificity in clinical specimens, providing novel prognostic information. This technique was also applied successfully to assess the HER family in a smaller number of DCIS cases. This novel technique and approach could potentially be applied for patient stratification and assist in the selection of more individualized treatment options according to tumour molecular characteristics.
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Molenaar, Jacobus. "Treatment decision support for early breast cancer patients." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2004. http://dare.uva.nl/document/77496.
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Blackwelder, Reid B. "Integrative Approaches to Treating Patients with Breast Cancer." Digital Commons @ East Tennessee State University, 2007. https://dc.etsu.edu/etsu-works/6985.
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Jansen, Catherine E. "Cognitive function in breast cancer patients undergoing chemotherapy." Diss., Search in ProQuest Dissertations & Theses. UC Only, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3261235.
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Donaghy, Kathleen B. "Biopsychosocial factors in breast cancer." Virtual Press, 1997. http://liblink.bsu.edu/uhtbin/catkey/1115723.
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In the treatment of early stage breast cancer, both mastectomy and lumpectomy followed by radiation therapy have been recognized as having similar survival rates. Increasingly, women are being given the opportunity to choose which of these surgical treatment options they wish to pursue. Decisions tend to be made rather quickly, and some women may later regret their treatment choice. In this study, an instrument (Breast Cancer Treatment Inventory (BCTI)) was developed that identified five primary sources of influence that affect women's breast cancer treatment decisions: cosmetic outcome, preparedness, physician's choice, short-term effects, and long-term effects. Items were generated and refined by oncology professionals and breast cancer survivors, followed by a pilot study conducted with members of a breast cancer support group. The resulting 28-item scale was completed by 139 early stage breast cancer patients. A series of oblique factor analyses yielded a five-factor solution with reliabilities ranging from .66 - .87. Content validity was enhanced by involving oncology experts and women with breast cancer in the item generation procedures. Use of the BCTI may assist women through a methodical and effective decision-making process. The BCTI may also be appropriate for research studiesinvolving the process and prediction of treatment selection since it meets requirements for ease of administration, brevity, reliability, and validity.Department of Counseling Psychology and Guidance Services
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Mak, Wai-ming Vivian. "Psychological predictors of marital adjustment in breast cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1998. http://hub.hku.hk/bib/B29726426.
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Bailey, A. Kathleen (Ann Kathleen). "Interactional Patterns in Families of Patients with Breast Cancer." Thesis, North Texas State University, 1985. https://digital.library.unt.edu/ark:/67531/metadc330997/.
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This study utilized ethnographic methodology to describe the communicative interactional patterns in families with a member who has breast cancer. Three breast cancer patients whose families were between the adolescent and launching of children developmental lifestage (McGoldrick & Carter, 1982) were chosen for the study. Data were collected from a series of three interview sessions over a period of four weeks with a two week time lapse between each of the interview sessions. Interview sessions were conducted in the families' homes by the researcher. All interviews were video and audio tape recorded for the purpose of preserving data for transcribing and coding. Research questions examined individual perception of meaning in regard to the disease, the structure and organization of the family in relation to the illness, and the effects of family communicative interaction on the course and management of the disease. Findings indicated that family members' responses to the diagnosis of "breast cancer were influenced by multi-generational "beliefs. All three families formulated a collective belief which supported the mother's belief about the disease. Each of the three families were mother-centered, and each mother seemed to use a metacommunicative approach to mediating family transactions. Each of the three fathers were reported as having been isolated and withdrawn within the family at various times. However, each father appeared to play a protective role in deflecting tension and stress away from the mother. All three couples appeared to have constructed an egalitarian relationship with an implicit agreement as to who was more skilled to hold the power within a particular context. In all three families, the generational boundaries were clearly defined. Conflict and affect were most generally expressed in an indirect manner through wit and sarcasm. However, because each of these three families were structured to allow for personal autonomous functioning of each individual member, patients were supported in seeking a modality outside of the family system to express more ambivalent feelings.
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Hadjisavvas, Andreas. "BRCA1, BRCA2 molecular study of Cypriot breast cancer patients." Thesis, Brunel University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250211.
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Poon, Yuet-fai Helena. "The psychological reactions of breast cancer patients with mastectomy." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B29697475.
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Shaw, Clare Elizabeth. "Diet, body weight and lymphodoema in breast cancer patients." Thesis, King's College London (University of London), 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.402098.
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Tahir, Mohammad. "Optimising the management of breast cancer in older patients." Thesis, University of Leicester, 2014. http://hdl.handle.net/2381/28827.
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This study aimed to optimise the treatment of early breast cancer in older patients. It tested the hypothesis that comprehensive geriatric assessment (CGA) could be used to predict two-year survival in older breast cancer patients. Based on the CGA scoring a treatment algorithm was devised that could help in recommending whether primary endocrine treatment (PET) or surgery plus endocrine treatment would be best indicated in individual patients. Methods: The study included women >70 years of age with early breast cancer, seen in a dedicated Leicester clinic between 01/2005 and 04/2007. All patients had comprehensive assessment including documentation of Satariano Index of Co-morbidities (SIC), Mini-Mental State Examination (MMSE), Geriatric Depression Score (GDS), Activities of Daily Living (ADL), Instrumental Activities of Daily Living (IADL) and American Society of Anaesthesiologists (ASA) grade. Logistic regression analysis explored any association between these components and two-year survival. Components with positive association were formulated into a Breast Cancer in Elderly Treatment Algorithm (BCETA). Results: 123 patients were included, age range 70-94 (median-82). Twenty-two patients died within two years. Logistic regression analysis found MMSE, ADL, and ASA score to have an independent association with two-year survival. The scores of these components were formulated into a BCETA. Logistic regression revealed a statistically significant association between the BCETA score and two-year survival (p-value 0.00). Other results for the BCETA prognostic model were: sensitivity 89%, specificity 46%, positive predictive value 87%, negative predictive value 52%, odds ratio 7.1 (95% CI 2.5-20.2), and overall accuracy of 81%. C-statistic value (area under ROC curve) for the BCETA score was 0.70. Conclusion: Breast Cancer in Elderly Treatment Algorithm is a new approach to optimise the management of breast cancer in elderly patients. It can help in identifying high-risk patients with expected short-survival who may benefit from PET, if their cancer is hormone receptor positive. Patients with predicted longer life expectancy (lowrisk) may be recommended standard treatment. Further studies are needed to validate it in a larger population.
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Cheng, Wing-ming Edward, and 鄭永明. "Emotional well-being in Chinese lung cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B3197157X.
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Opincariu, Marius. "Counseling the terminally ill patients with cancer in hospital." Online full text .pdf document, available to Fuller patrons only, 2003. http://www.tren.com.
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Swartz, Esti. "Emotional intelligence and locus of control of adult breast cancer patients receiving treatment." Thesis, Nelson Mandela Metropolitan University, 2010. http://hdl.handle.net/10948/d1015686.
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Breast cancer is the most prevalent cancer of women in South Africa, with one in twenty-seven women diagnosed with breast cancer in their lifetime. By building on human strengths, ways can be found to cope effectively with adversity. This will contribute to psychological well-being and result in living constructive and meaningful lives. Emotional intelligence and locus of control are two constructs which, according to previous research, may be associated with psychological wellbeing. Limited research has been conducted on these constructs in populations facing adversity. Adaptation to breast cancer treatment is considered to be an extremely difficult process. The research aimed to explore and describe emotional intelligence and locus of control within an adult breast cancer population. A sample of 67 breast cancer patients receiving treatment was approached to complete a biographical questionnaire and two pencil-and-paper questionnaires. Descriptive and inferential statistics were be used to analyze the data. The results of the quantitative analysis indicated a significant negative correlation between emotional intelligence and locus of control which shows that patients with higher levels of emotional intelligence possess more internal locus of control orientations, while patients with lower emotional intelligence possess more external locus of control orientations. The population presented with above average emotional intelligence and an internal locus of control orientation. The study can be regarded as the first step in opening a field of research which could contribute to more effective coping and the overall psychological well-being of individuals facing adversity in South Africa. Furthermore, the findings of the study contributed to understanding the role of emotional intelligence and locus of control in these populations and encouraged further research and the development and implementation of programmes that promote skills development in these areas.
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Zucchero, Renee A. "Marital adjustment of older adult couples with breast cancer, prostate cancer, and couples without cancer." Virtual Press, 1998. http://liblink.bsu.edu/uhtbin/catkey/1117099.
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The purpose of this study was to explore the marital adjustment of older adult couples with breast cancer, prostate cancer, and couples who have experienced neither. Participants were 64 couples in which at least one of the spouses was over 55 years of age, including 19 breast cancer couples, 20 prostate cancer couples, 25 couples who had experienced neither of these cancers. Most participants were young-old, Protestant, Caucasians from a high socioeconomic class. The breast cancer and prostate cancer participants had completed treatment an average of 39.5 months prior to participation. The methodology was a mail survey. Participants completed a demographic questionnaire, the Marital Satisfaction Questionnaire for Older Adults (MSQFOP) (Haynes et al., 1992), Primary Communication Inventory (PCI) (Navran, 1967), Miller Social Intimacy Scale (MSIS) (Miller & Lefcourt, 1982), and the Index of Sexual Satisfaction (ISS) (Hudson et al., 1981).There were no differences in the amount of discordance between the couples groups' level of marital satisfaction, communication, intimacy, and sexual satisfaction. In addition, there were no differences in the level of marital satisfaction, communication, intimacy, and sexual satisfaction between the participant groups. There was a significantly greater correlation between the prostate cancer couples' scores on the ISS than the correlation between the breast cancer couples' scores and the scores of the couples who had not experienced breast cancer or prostate cancer.The level of marital satisfaction, communication, intimacy, and sexual satisfaction reported was similar to that of the normative samples. There was no difference between the marital adjustment of the cancer couples and older couples who had experienced neither type of cancer. These results are good news for breast and prostate cancer survivors, and professionals. Older adults may be better able to incorporate the experience of cancer into their lives or are better prepared for chronic illness through anticipatory socialization. The high degree of agreement between the prostate cancer spouses on the ISS may be related to the sexual dysfunction that frequently accompanies treatment for this cancer. Future research should be qualitative and longitudinal and continue to explore the psychosocial implications of prostate cancer.Center for Gerontology
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Hauser, Robert Sean. "Utilities of metastatic breast cancer patients treated with taxanes compared to utilities of oncology nurses." Access restricted to users with UT Austin EID Full text (PDF) from UMI/Dissertation Abstracts International, 2001. http://wwwlib.umi.com/cr/utexas/fullcit?p3035947.
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Hackman, Marcia. "Coping strategies of women with breast cancer." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276869.
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An ethnographic study was utilized to identify coping strategies of women with breast cancer. Five women were interviewed; four were interviewed on three separate occasions, and one was interviewed twice. The data were analyzed for specific coping strategies taken by the women to deal with the stresses of breast cancer. These strategies were compared and organized into categories of coping strategies: Actions Taken, Emotional Support, Positive Outcomes, Getting Control, and Keeping a Positive Attitude. These five categories were integrated as new coping incidents appeared in the data. The original five categories were merged into three categories: Getting Control, Compensating, and Emotional Support. From these three categories the theory was written: Women with breast cancer will obtain support, get control over what they can control, and compensate for what they cannot control.
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Göthlin, Eremo Anna. "Biological profiles of endocrine breast cancer." Doctoral thesis, Örebro universitet, Institutionen för hälsovetenskap och medicin, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-43963.
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Funding: Magnus Bergvall Cancer Foundation; Percy Falk foundation for research in breast and prostate cancer; Nyckelfonden; Örebro University Hospital; Lions cancer research foundation, Region Uppsala-Örebro
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Lo, Hau-yan Phyllis. "Understanding breast cancer patients a 3-year follow-up study on psychosocial support groups /." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42182189.
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Fertsch, Sonia Maria [Verfasser], and Christoph [Akademischer Betreuer] Andree. "Cancer recurrence risk after lipofilling in breast cancer patients with DIEP flap reconstruction." Freiburg : Universität, 2016. http://d-nb.info/1122743343/34.
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Möller, Ernst Lodewicus. "Patient reported outcome measures (PROMs) in breast cancer patients after immediate breast reconstruction using the Breast-Q." Master's thesis, Faculty of Health Sciences, 2021. http://hdl.handle.net/11427/32865.
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Background Mastectomy is the mainstay of surgical treatment for women with breast cancer in South Africa. The increase in breast reconstruction after a mastectomy has prompted the need to evaluate patient reported outcome measures (PROMs) for this set of operative intervention. This study aimed to assess clinical and patient reported outcome measures in immediate breast reconstruction patients using the BREAST-Q and compare these with international cohorts. Methods A cross-sectional study was performed on all patients who underwent immediate breast reconstruction between January 2011 and December 2016. This consisted of a retrospective clinical record review of perioperative outcomes, and a quality of life analysis using the BREAST-Q Post-Reconstruction questionnaire. Outcome predictors were identified using Chi-square, Fisher exact, One-way ANOVA, Student t-tests and Kruskal Wallis analysis of variance. A random-effect single arm meta-analysis was performed to compare the BREASTQ scores with international cohorts. Results A total of 52 patients were included with a mean age of 43.2 (+/-9.5) years. Eighteen patients (34.6%) developed early complications; of these 8 (44.4%) were major. Thirty-one patients (59.6%) developed late complications; of these 18 (58.1%) were major. Fifteen patients (28.8%) had failed reconstruction. There was a significantly higher risk of failure following a total mastectomy (TM) (p=0.02), tissue expander reconstruction (TE) (p< 0.01) and stage 2 breast cancer (p=0.01). Patients who underwent nipple reconstruction and immediate-delayed reconstruction before 12 months, reported higher well-being and satisfaction scores. Compared to international cohorts our BREAST-Q scores were lower but fall within the 95% confidence interval for Sexual Well-Being and Satisfaction with Nipples and Care. Conclusion Immediate breast reconstruction poses a high risk of complications and reconstructive failure especially, with TM and TE. Our BREAST-Q scores are comparable to international studies and may be useful in guiding patient consent.
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Yuen, Hang-yuk. "A study of sexual dysfunction in female breast cancer patients /." Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19470794.
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Ramroth, Johanna Rankin. "Radiotherapy dose-fractionations and outcomes in cancer patients." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:8c5a99de-7d8c-4b19-9a91-e6cf4efa7bd2.
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Radiotherapy cures many cancers, but the optimum total doses and fractionations used to treat different cancer types remain uncertain. While conventional fractionation (≈2 Gy per fraction) is common in many countries, UK practice has been highly variable. This thesis compared different curative-intent radiotherapy dose-fractionations used in non-small cell lung and breast cancer. These two cancers together make up over a quarter of UK cancer incidence and mortality, and radiotherapy can increase cure rates of both cancers. Two studies were conducted: (A) A meta-analysis of randomised radiotherapy trials in non-small cell lung cancer and (B) A cohort study of non-small cell lung and breast cancer radiotherapy in the Thames Valley. For the meta-analysis, a systematic search was conducted. Eligible studies were randomised comparisons of two or more radiotherapy regimens. Median survival ratios were calculated for each comparison and pooled. 3,795 patients in 25 randomised comparisons of radiotherapy dose were studied. When radiotherapy was given alone, the higher dose within-trial resulted in increased survival (median survival ratio 1.13, 95% confidence interval 1.04-1.22). When radiotherapy was given with concurrent chemotherapy, the higher dose within-trial resulted in decreased survival (median survival ratio 0.83, 95% confidence interval 0.71-0.97). For the cohort study, multiple Public Health England data sources were combined to obtain information on radiotherapy, patient characteristics, and outcomes. Multivariable Cox regressions were conducted separately by cancer site. 324 non-small cell lung, 8,879 invasive breast, and 477 ductal carcinoma in situ patients were studied. In analyses of both non-small cell lung and invasive breast cancer, increasing radiotherapy dose was associated with improved survival in some treatment centres, while in other centres the opposite was true. These opposite trends by treatment centre were unlikely to be explained by chance, and they suggest that differences in patient selection were driving results. There were insufficient events among ductal carcinoma in situ patients to assess associations. Findings from the meta-analysis support consideration of further radiotherapy dose escalation trials, making use of modern methods to reduce toxicity. Findings from the cohort study suggest that it is not possible to use observational studies to examine causal effects of radiotherapy dose-fractionation. This thesis therefore shows the continued importance of conducting sufficiently large randomised trials to ascertain optimal dose-fractionation in radiotherapy.
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Wilczek, Brigitte. "Application of nuclear medicine methods in patients with breast cancer /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-340-X/.
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Soerjomataram, Isabelle. "Multiple primary cancers in patients with breast ans skin cancer." [S.l.] : Rotterdam : [The Author] ; Erasmus University [Host], 2007. http://hdl.handle.net/1765/10779.
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Teh, Li Ling Grace. "Psychological and biochemical parameters of stress in breast cancer patients /." Adelaide, 1997. http://web4.library.adelaide.edu.au/theses/09ARPS/09arpst261.pdf.
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Taylor, Kimberly. "Fertility education needs and disparities in female breast cancer patients." Connect to resource, 2008. http://hdl.handle.net/1811/32238.
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Brennan, Sarah Frances Mary. "Diet, lifestyle and quality of life in breast cancer patients." Thesis, Queen's University Belfast, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579612.
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Despite much research investigating the role of diet and lifestyle in breast cancer, the evidence for many dietary factors remains uncertain. The main focus of this thesis concerns the role of dietary patterns and fat in breast cancer risk and also recurrence and survival in breast cancer patients. Meta-analyses conducted in this thesis have suggested that a prudent dietary pattern may reduce the risk of breast cancer, whilst a drinker dietary pattern may increase risk. High saturated fat intake was also found to be associated with breast cancer mortality. Data obtained from participants of the DietCompLyf study, a prospective cohort of breast cancer patients in the UK, was used in this thesis to investigate dietary patterns and fat intake in relation to breast cancer recurrence and quality of life. The physical activity questionnaire used in the DietCompLyf study was also retrospectively validated in this thesis to determine how best to use the physical activity information as a confounder in the" diet and breast cancer recurrence and quality of life analyses in this thesis. In participants of the DietCompLyf study, adherence to a Traditional dietary pattern was associated with an increased risk of breast cancer recurrence. A prudent dietary pattern was associated with a better quality of life, whilst Western dietary patterns associated with a poorer quality of life in unadjusted analyses. The complicated nature of the diet and quality of life relationship was highlighted when adjustment for potential confounders modified and attenuated the observed associations. Results observed in this thesis suggest possible roles for diet in both risk of breast cancer and breast cancer mortality. Further analyses of data obtained from the DietCompLyf cohort should be conducted in the future to clarify theses observations.
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Brazil, Lucy Caroline Alexandra. "Gene Expression in High-risk Breast and Ovarian Cancer Patients." Thesis, Institute of Cancer Research (University Of London), 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.504783.
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Germline mutations in human BRCA 1 and BRCA2 genes confer a lifetime risk of breast cancer of between 60 and 85% and a lifetime risk of ovarian cancer of between 15 and 40%. Identification of mutations in these genes either in healthy carriers or in those who have already developed cancer is important for clinical management, including prophylactic measures to reduce the risk of disease. BRCA 1 and BRCA2 were identified more than 10 years ago, but due to a number of features such as large gene size and heterogeneity of mutations, genetic testing of BRCA is both labour intensive and often inconclusive. The aim of this project is to find a characteristic phenotype that is indicative of BRCA heterozygosity in individuals without clinical signs of disease. This could be used as a functional preliminary screen for these high-risk patients. Previous studies have illustrated the differences in gene expression profiles between 'normal' and BReA derived tumours. Studies using chicken DT 40 cell lines have shown that a Brca2 heterozygote phenotype exil:?ts but, this is as yet to be conClusively demonstrated in humans. . In this study, gene expression profiles, from 'healthy' patients who are heterozygous for BRCA have been analysed using data from microarrays. RNA was prepared from immortalized Epstein-Barr virus transformed human lymphocyte (EBVTL) cell lines, taken from normal controls and carriers for BRCA 1 and BRCA2 mutations. Gene expression profiies were also assessed before and after exposure to DNA damaging agents.
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Yuen, Hang-yuk, and 袁亨玉. "A study of sexual dysfunction in female breast cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1996. http://hub.hku.hk/bib/B31250336.
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Kanatas, Anastasios. "Development of a breast cancer specific patients concerns inventory (PCI)." Thesis, University of Liverpool, 2013. http://livrepository.liverpool.ac.uk/13339/.
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Introduction: Treating breast cancer is based on a combination of therapies: surgery, radiotherapy, chemotherapy, as well as hormonal and biological agents. The full impact of the disease and its treatment at a human level is often underestimated, and the benefits of holistic cancer care are increasingly recognised. Furthermore, patients often face a frightening and uncertain journey that presents a variety of needs. Moreover, recovery is not necessarily the end-point of the cancer experience. The many complexities and challenges in the identification of patient issues along this journey can lead to unmet needs. This can be particularly difficult in the confines of a busy clinic, where time constraints, together with an over-reliance on verbal communication, can pose significant barriers to effective consultations. A novel tool, known as the patient concerns inventory (PCI), has been successfully developed and introduced for use in patients with head and neck cancer. In this setting, it has helped to formulate an individualized record of patient concerns, needs, and priorities, thereby structuring outpatient consultations, and promoting and facilitating a multidisciplinary approach. This study aimed to develop and assess a PCI specific to breast cancer and to evaluate its impact on patient care; that is, to provide a “proof of concept” for a breast cancer PCI. Methods: This was a four-phase study, as follows. (1) Item generation through a literature review, input from clinicians (n = 10), four patient focus groups (n = 24), and national breast cancer charities (n = 3). (2) A survey of breast cancer patients (n = 200) for cross-sectional validation, to compare the PCI with an established quality of life tool and to look at the relative frequency of items and any associations. (3) A pilot, before and after study, assessing the PCI in a clinical setting with breast cancer patients (n = 53). (4) Semi-structured interviews with a breast surgeon (n = 1) and specialist nurses (n = 2) who used the PCI during clinics, to identify the perceived benefits of using the PCI. Results: In total 277 patients responded and participated in this work. The literature review identified 164 items; following input from clinicians, focus groups, and national charities, 56 items remained. The cross sectional study (phase 2; n=200, 80 % response rate) revealed that patients wanted to discuss the following: breast sensitivity or pain (46 %), fatigue (46 %), hot flushes (44 %), sleep (34 %); breast appearance (30 %), unable to control weight (28 %), mastectomy appearance (19 %), overall physical appearance (17 %); fear of recurrence (62 %), fear of cancer spreading (39 %), fear about the future (32 %), or one or more of these (72 %); ‘mood’ (15 %), ‘anxiety’ (21 %), ‘depression’ (17 %), or one or more of these (35 %); Phase 3 found that the PCI resulted in a focused consultation and no increase in consultation time. All the patients from phase 3 wanted to see a breast surgeon. Phase 4 revealed that clinicians involved with the PCI supported its use, and stated several advantages. In its final format, the breast cancer specific PCI had 57 items over several domains, with 16 referral options. Conclusions: The PCI could identify issues that patients would like to discuss in the breast oncology clinic. The routine use of the PCI in follow-up clinics could ultimately improve care for women with breast cancer; however, the clinical environment continues to make it difficult to screen for issues related to intimacy, relationship, and sex. Further research is essential to evaluate the breast cancer specific PCI. A larger patient cohort, a longitudinal approach, qualitative input, and a link to possible interventions, would each improve our understanding of the issues faced by breast cancer patients.
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Yeung, Shuk-chong Rene, and 楊淑莊. "Self-evaluation of coping resources of cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B31250750.
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Ho, Tin-hung Rainbow. "Psychophysiological effects of psychosocial interventions : an example of breast cancer patients in Hong Kong." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31049060.
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Chan, Yu. "An exploratory study on spiritually and psychosocial well-being in chinese breast cancer patients." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B40887832.
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Walsh, Dicks Elizabeth L. "Surgery for breast cancer in St. John's : the statistics, the surgeons' view, the patients' view /." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0032/MQ47486.pdf.
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Chan, Wing-chiu Michelle. "Relationships between attentional bias, posttraumatic growth, and psychopathology in breast cancer patients." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41712614.
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Wade, Walsh Margo. "Women Receiving Genetic Counseling for Breast Cancer Risk: Cancer Worry, Psychological Distress, and Risk Recall Accuracy." Thesis, University of North Texas, 1999. https://digital.library.unt.edu/ark:/67531/metadc2185/.
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This follows an earlier study of the same data set, which, through its findings, presented new questions that are investigated in this study. Both studies used a prospective controlled design, wherein women receiving genetic counseling for breast cancer risk were randomized into two groups. Subjects receiving an audiotaped recording of their genetic consultation (tape group) were compared to subjects who also had a genetic consultation but did not receive an audiotaped recording of it (no-tape group). Participants were drawn from attendees at the genetic clinics of two London hospitals and included 115 women with a family history of breast cancer. Cancer worry and psychological distress were assessed before genetic consultation (baseline), and at one- and six-month follow-ups by post. Objective risk was estimated by the geneticist during the consultation, and subjective risk was assessed at one month follow-up. The goals of the current study were to investigate relationships between cancer worry, psychological distress, and recall of genetic risk for breast cancer in a sample of women receiving genetic counseling for breast cancer risk, and to investigate the role sociodemographic variables on cancer worry, psychological distress, or risk recall for these women. Results for this sample of women with a family history of breast cancer found that there were consistent relationships between cancer worry, psychological distress, objective risk, and subjective risk before and after genetic consultation. This suggests that women=s psychological responses are appropriate to their level of cancer risk. There were no differences found between the tape and no-tape groups for objective or subjective risk, or for nearness of recall accuracy or degree of under-/over-estimation. Provision of an audiotaped recording of the genetic consultation did not appear to enhance recall of risk information. The role of sociodemographic variables on the psychological and risk variables assessed in this study was very minor. Age was mildly correlated with cancer worry, and employment was predictive of cancer worry only at baseline.
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Wu, Peihua, and 吳佩樺. "Effects Of A Psycho-Education Counseling Program With Breast Cancer Patients Undergoing Chemotherapy." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/59917749993930044846.
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碩士義守大學
管理學院管理碩士在職專班
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This research investigated the effect of the psycho-education counseling program on anxiety, depression, disease-specific knowledge, quality of life, self-efficacy and resilience among breast cancer patients during the chemotherapy period. A total of 40 patients over 20 years old with a diagnosis of breast cancer were recruited from a medical teaching hospital in the southern Taiwan. The psycho-education counseling program and educational manual were used as intervention programmes in this study. The purpose of the educational manual was to describe important health issues associated with cancer management and self-care and to provide a user-friendly guide. The contents of the educational information and materials consisted of six themes, namely provision of social and emotional support and disease-specific knowledge, promotion of emotional expression, education messages, case analysis, related scenarios, self-monitoring, essays and and evaluation, and use of complementary and alternative medicine. Participants in the experimental group (n = 20) received six sessions of psycho-education counseling program and the educational manual. Participants in the control group (n= 20) were exposed only to the traditional education approach (consultation from psychiatrists and information sheets). The research instruments included basic characteristics of participants and scales of hospital anxiety and depression, chemotherapeutic knowledge, quality of life for cancer patients, self-efficacy and the resilience. Data were collected just before the chemotherapy (T1), the 3rd (T2) and 5th chemotherapy (T3), and 2 weeks after the final session of chemotherapy (T4). The results revealed that the levels of both anxiety and depression of the experimental group were lower than the control group, and showed significant differences at T4. Disease-specific knowledge scores increased in the experimental group, compared with the control group, and also had significant differences at T2 and T4. Quality of life at T4 was significantly improved between groups. Self-efficacy at T2 showed no significant differences in both groups; however, it was significantly improved at T3 and T4 between groups. Resilience was improved significantly between groups at T4. The results indicated that the psycho-education counseling program improved breast cancer patient’s anxiety, depression, disease-specific knowledge, quality of life, self-efficacy and resilience. Nurses can apply this intervention in breast cancer patients undergoing chemotherapy to promote their quality of life, and improve the quality of oncology nursing care.