Journal articles on the topic 'Brd7'
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Hay, Duncan A., Catherine M. Rogers, Oleg Fedorov, Cynthia Tallant, Sarah Martin, Octovia P. Monteiro, Susanne Müller, Stefan Knapp, Christopher J. Schofield, and Paul E. Brennan. "Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomains." MedChemComm 6, no. 7 (2015): 1381–86. http://dx.doi.org/10.1039/c5md00152h.
Full textAli, Maria Mushtaq, Sajda Ashraf, Mohammad Nure-e-Alam, Urooj Qureshi, Khalid Mohammed Khan, and Zaheer Ul-Haq. "Identification of Selective BRD9 Inhibitor via Integrated Computational Approach." International Journal of Molecular Sciences 23, no. 21 (November 4, 2022): 13513. http://dx.doi.org/10.3390/ijms232113513.
Full textShi, Mingsong, Jun He, Tiantian Weng, Na Shi, Wenyan Qi, Yong Guo, Tao Chen, Lijuan Chen, and Dingguo Xu. "The binding mechanism of NHWD-870 to bromodomain-containing protein 4 based on molecular dynamics simulations and free energy calculation." Physical Chemistry Chemical Physics 24, no. 8 (2022): 5125–37. http://dx.doi.org/10.1039/d1cp05490b.
Full textLim, Ratana, Caitlyn Nguyen-Ngo, and Martha Lappas. "Targeting bromodomain-containing proteins to prevent spontaneous preterm birth." Clinical Science 133, no. 23 (December 2019): 2379–400. http://dx.doi.org/10.1042/cs20190919.
Full textKapoor, Sabeeta, and Roderick H. Dashwood. "Abstract 5712: Dietary polyphenols as BRD7 and 9 inhibitors for cancer interception." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5712. http://dx.doi.org/10.1158/1538-7445.am2022-5712.
Full textLee, Junsik M., Renyan Liu, and Sang Won Park. "The regulatory subunits of PI3K, p85α and p85β, differentially affect BRD7-mediated regulation of insulin signaling." Journal of Molecular Cell Biology 13, no. 12 (November 9, 2021): 889–901. http://dx.doi.org/10.1093/jmcb/mjab073.
Full textClark, Peter G. K., Darren J. Dixon, and Paul E. Brennan. "Development of chemical probes for the bromodomains of BRD7 and BRD9." Drug Discovery Today: Technologies 19 (March 2016): 73–80. http://dx.doi.org/10.1016/j.ddtec.2016.05.002.
Full textPark, Sang Won, and Junsik M. Lee. "Emerging Roles of BRD7 in Pathophysiology." International Journal of Molecular Sciences 21, no. 19 (September 27, 2020): 7127. http://dx.doi.org/10.3390/ijms21197127.
Full textCrodian, Jennifer S., Bethany M. Weldon, Yu-Chun Tseng, Birgit Cabot, and Ryan Cabot. "Nuclear trafficking dynamics of Bromodomain-containing protein 7 (BRD7), a switch/sucrose non-fermentable (SWI/SNF) chromatin remodelling complex subunit, in porcine oocytes and cleavage-stage embryos." Reproduction, Fertility and Development 31, no. 9 (2019): 1497. http://dx.doi.org/10.1071/rd19030.
Full textKZHYSHKOWSKA, Julia, Andre RUSCH, Hans WOLF, and Thomas DOBNER. "Regulation of transcription by the heterogeneous nuclear ribonucleoprotein E1B-AP5 is mediated by complex formation with the novel bromodomain-containing protein BRD7." Biochemical Journal 371, no. 2 (April 15, 2003): 385–93. http://dx.doi.org/10.1042/bj20021281.
Full textSample, Reilly A., and Rachel Paolini. "77232 The role of the bromodomain and extra-terminal motif (BET) family of proteins in head and neck cancer tumorigenic phenotype." Journal of Clinical and Translational Science 5, s1 (March 2021): 5. http://dx.doi.org/10.1017/cts.2021.415.
Full textRiching, Kristin M., James D. Vasta, Scott J. Hughes, Vittoria Zoppi, Chiara Maniaci, Andrea Testa, Marjeta Urh, Alessio Ciulli, and Danette L. Daniels. "Translating PROTAC chemical series optimization into functional outcomes underlying BRD7 and BRD9 protein degradation." Current Research in Chemical Biology 1 (2021): 100009. http://dx.doi.org/10.1016/j.crchbi.2021.100009.
Full textZhou, Ming, Xiao-Jie Xu, Hou-De Zhou, Hua-Ying Liu, Jia-Jin He, Xiao-Ling Li, Cong Peng, et al. "BRD2 is one of BRD7-interacting proteins and its over-expression could initiate apoptosis." Molecular and Cellular Biochemistry 292, no. 1-2 (June 20, 2006): 205–12. http://dx.doi.org/10.1007/s11010-006-9233-4.
Full textKim, A. L., G. C. Jin, Y. Zhu, and D. R. Bickers. "227 Bromodomain-containing proteins BRD7 and BRD9 are novel interacting regulators of BCC resistance." Journal of Investigative Dermatology 138, no. 5 (May 2018): S38. http://dx.doi.org/10.1016/j.jid.2018.03.232.
Full textYu, Zhifeng, Angela F. Ku, Justin L. Anglin, Rajesh Sharma, Melek Nihan Ucisik, John C. Faver, Feng Li, et al. "Discovery and characterization of bromodomain 2–specific inhibitors of BRDT." Proceedings of the National Academy of Sciences 118, no. 9 (February 26, 2021): e2021102118. http://dx.doi.org/10.1073/pnas.2021102118.
Full textTseng, Yu-Chun, Jennifer S. Crodian, and Ryan Cabot. "Depletion of SMARCB1 and BRD7, two SWI/SNF chromatin remodelling complex subunits, differentially impact porcine embryo development." Reproduction, Fertility and Development 34, no. 7 (March 17, 2022): 549–59. http://dx.doi.org/10.1071/rd21251.
Full textWu, Wen-Jing, Kai-Shun Hu, Dong-Liang Chen, Zhao-Lei Zeng, Hui-Yan Luo, Feng Wang, De-Shen Wang, Zhi-Qiang Wang, Fan He, and Rui-Hua Xu. "Prognostic relevance of BRD7 expression in colorectal carcinoma." European Journal of Clinical Investigation 43, no. 2 (December 7, 2012): 131–40. http://dx.doi.org/10.1111/eci.12024.
Full textLiu, Huaying, Cong Peng, Ming Zhou, Jie Zhou, Shourong Shen, Houde Zhou, Wei Xiong, et al. "Cloning and Characterization of the BRD7 Gene Promoter." DNA and Cell Biology 25, no. 6 (June 2006): 346–58. http://dx.doi.org/10.1089/dna.2006.25.346.
Full textCoudé, Marie-Magdelaine, Thorsten Braun, Jeannig Berrou, Mélanie Dupont, Raphael Itzykson, Aline Masse, Emmanuel Raffoux, et al. "Bromodomain Inhibition By OTX015 Regulates c-MYC and HEXIM1 in a Panel of Human Acute Leukemia Cell Lines." Blood 124, no. 21 (December 6, 2014): 5957. http://dx.doi.org/10.1182/blood.v124.21.5957.5957.
Full textKempen, Herman J., Daniel Bellus, Oleg Fedorov, Silke Nicklisch, Panagis Filippakopoulos, Sarah Picaud, and Stefan Knapp. "Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding." Lipid Insights 6 (January 2013): LPI.S13258. http://dx.doi.org/10.4137/lpi.s13258.
Full textStonestrom, Aaron J., Sarah C. Hsu, Kristen S. Jahn, Peng Huang, Cheryl A. Keller, Belinda M. Giardine, Stephan Kadauke, et al. "Functions of BET proteins in erythroid gene expression." Blood 125, no. 18 (April 30, 2015): 2825–34. http://dx.doi.org/10.1182/blood-2014-10-607309.
Full textOttinger, Matthias, Thomas Christalla, Kavita Nathan, Melanie M. Brinkmann, Abel Viejo-Borbolla, and Thomas F. Schulz. "Kaposi's Sarcoma-Associated Herpesvirus LANA-1 Interacts with the Short Variant of BRD4 and Releases Cells from a BRD4- and BRD2/RING3-Induced G1 Cell CycleArrest." Journal of Virology 80, no. 21 (August 23, 2006): 10772–86. http://dx.doi.org/10.1128/jvi.00804-06.
Full textLong, Mengping, Wei Hou, Yiqiang Liu, and Taobo Hu. "A Histone Acetylation Modulator Gene Signature for Classification and Prognosis of Breast Cancer." Current Oncology 28, no. 1 (February 17, 2021): 928–39. http://dx.doi.org/10.3390/curroncol28010091.
Full textPARK, SANG, YOUNGAH HAN, and MARIO A. SALAZAR HERNANDEZ. "The Regulation of BRD7 in the Insulin Signaling Pathway." Diabetes 67, Supplement 1 (May 2018): 1983—P. http://dx.doi.org/10.2337/db18-1983-p.
Full textWang, Lifei, Yan Wang, Juan Zhao, Yingxia Yu, Nianqian Kang, and Zhiyong Yang. "Theoretical exploration of the binding selectivity of inhibitors to BRD7 and BRD9 with multiple short molecular dynamics simulations." RSC Advances 12, no. 26 (2022): 16663–76. http://dx.doi.org/10.1039/d2ra02637f.
Full textWang, Lifei, Yan Wang, Juan Zhao, Yingxia Yu, Nianqian Kang, and Zhiyong Yang. "Theoretical exploration of the binding selectivity of inhibitors to BRD7 and BRD9 with multiple short molecular dynamics simulations." RSC Advances 12, no. 26 (2022): 16663–76. http://dx.doi.org/10.1039/d2ra02637f.
Full textRashad, Maha M., Mona K. Galal, Adel M. EL-Behairy, Eman M. Gouda, and Said Z. Moussa. "Maternal exposure to di-n-butyl phthalate induces alterations of c-Myc gene, some apoptotic and growth related genes in pups’ testes." Toxicology and Industrial Health 34, no. 11 (September 19, 2018): 744–52. http://dx.doi.org/10.1177/0748233718791623.
Full textLEE, JUNSIK M., YOO KIM, MARIO A. SALAZAR HERNANDEZ, and SANG PARK. "305-LB: BRD7 Deficiency Leads to the Development of Obesity." Diabetes 68, Supplement 1 (June 2019): 305—LB. http://dx.doi.org/10.2337/db19-305-lb.
Full textGao, Yushun, Bing Wang, and Shugeng Gao. "BRD7 Acts as a Tumor Suppressor Gene in Lung Adenocarcinoma." PLOS ONE 11, no. 8 (August 31, 2016): e0156701. http://dx.doi.org/10.1371/journal.pone.0156701.
Full textYU, Ying. "Screening of BRD7 interacting proteins by yeast two-hybrid system." Science in China Series C 45, no. 5 (2002): 546. http://dx.doi.org/10.1360/02yc9060.
Full textPark, Young-Ae, Jeong-Won Lee, Jung-Joo Choi, Hye-Kyung Jeon, YoungJae Cho, ChelHun Choi, Tae-Joong Kim, Nak Woo Lee, Byoung-Gie Kim, and Duk-Soo Bae. "The interactions between MicroRNA-200c and BRD7 in endometrial carcinoma." Gynecologic Oncology 124, no. 1 (January 2012): 125–33. http://dx.doi.org/10.1016/j.ygyno.2011.09.026.
Full textWang, Xiao-meng, Ying-cui Wang, Xiang-juan Liu, Qi Wang, Chun-mei Zhang, Li-ping Zhang, Hui Liu, Xin-yu Zhang, Yang Mao, and Zhi-ming Ge. "BRD7 mediates hyperglycaemia-induced myocardial apoptosisviaendoplasmic reticulum stress signalling pathway." Journal of Cellular and Molecular Medicine 21, no. 6 (December 13, 2016): 1094–105. http://dx.doi.org/10.1111/jcmm.13041.
Full textLiu, Huaying, Ming Zhou, Xiaomin Luo, Liming Zhang, Zhaoxia Niu, Cong Peng, Jian Ma, et al. "Transcriptional regulation of BRD7 expression by Sp1 and c-Myc." BMC Molecular Biology 9, no. 1 (2008): 111. http://dx.doi.org/10.1186/1471-2199-9-111.
Full textWang, Na, Fudong Li, Hongyu Bao, Jie Li, Jihui Wu, and Ke Ruan. "NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains." ChemBioChem 17, no. 15 (June 27, 2016): 1456–63. http://dx.doi.org/10.1002/cbic.201600184.
Full textWang, Xin, Ana P. Kutschat, Moyuru Yamada, Evangelos Prokakis, Patricia Böttcher, Koji Tanaka, Yuichiro Doki, Feda H. Hamdan, and Steven A. Johnsen. "Bromodomain protein BRDT directs ΔNp63 function and super-enhancer activity in a subset of esophageal squamous cell carcinomas." Cell Death & Differentiation 28, no. 7 (March 3, 2021): 2207–20. http://dx.doi.org/10.1038/s41418-021-00751-w.
Full textCiulli, Alessio. "Targeted Protein Degradation with Small Molecules: How PROTACs Work." Proceedings 22, no. 1 (December 16, 2019): 115. http://dx.doi.org/10.3390/proceedings2019022115.
Full textMantovani, Fiamma, Jarno Drost, P. Mathijs Voorhoeve, Giannino Del Sal, and Reuven Agami. "Gene regulation and tumor suppression by the bromodomain-containing protein BRD7." Cell Cycle 9, no. 14 (July 15, 2010): 2849–53. http://dx.doi.org/10.4161/cc.9.14.12309.
Full textZhang, Zili, Mei Guo, Min Shen, Desong Kong, Feng Zhang, Jiangjuan Shao, Shanzhong Tan, et al. "The BRD7-P53-SLC25A28 axis regulates ferroptosis in hepatic stellate cells." Redox Biology 36 (September 2020): 101619. http://dx.doi.org/10.1016/j.redox.2020.101619.
Full textChiu, Yu-Hsin, Jennifer Y. Lee, and Lewis C. Cantley. "BRD7, a Tumor Suppressor, Interacts with p85α and Regulates PI3K Activity." Molecular Cell 54, no. 1 (April 2014): 193–202. http://dx.doi.org/10.1016/j.molcel.2014.02.016.
Full textGolick, Lena, Youngah Han, Yoo Kim, and Sang Won Park. "BRD7 regulates the insulin-signaling pathway by increasing phosphorylation of GSK3β." Cellular and Molecular Life Sciences 75, no. 10 (November 10, 2017): 1857–69. http://dx.doi.org/10.1007/s00018-017-2711-x.
Full textDrost, Jarno, Fiamma Mantovani, Francesca Tocco, Ran Elkon, Anna Comel, Henne Holstege, Ron Kerkhoven, et al. "BRD7 is a candidate tumour suppressor gene required for p53 function." Nature Cell Biology 12, no. 4 (March 14, 2010): 380–89. http://dx.doi.org/10.1038/ncb2038.
Full textXu, Liang, Ye Chen, Anand Mayakonda, Lynnette Koh, Yuk Kien Chong, Dennis L. Buckley, Edwin Sandanaraj, et al. "Targetable BET proteins- and E2F1-dependent transcriptional program maintains the malignancy of glioblastoma." Proceedings of the National Academy of Sciences 115, no. 22 (May 15, 2018): E5086—E5095. http://dx.doi.org/10.1073/pnas.1712363115.
Full textXu, Chunmei, Miao Yu, Qingqing Zhang, Zhisheng Ma, Kang Du, Huiqin You, Jing Wei, Deshou Wang, and Wenjing Tao. "Genome-Wide Identification and Characterization of the BRD Family in Nile Tilapia (Oreochromis niloticus)." Animals 12, no. 17 (September 1, 2022): 2266. http://dx.doi.org/10.3390/ani12172266.
Full textLiu, Zhixiong, Minbiao Yan, Yaoji Liang, Min Liu, Kun Zhang, Dandan Shao, Rencai Jiang, et al. "Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination." Neuron 102, no. 3 (May 2019): 587–601. http://dx.doi.org/10.1016/j.neuron.2019.02.018.
Full textKarim, Rezaul Md, Alice Chan, Jin-Yi Zhu, and Ernst Schönbrunn. "Structural Basis of Inhibitor Selectivity in the BRD7/9 Subfamily of Bromodomains." Journal of Medicinal Chemistry 63, no. 6 (February 24, 2020): 3227–37. http://dx.doi.org/10.1021/acs.jmedchem.9b01980.
Full textClark, Peter G. K., Lucas C. C. Vieira, Cynthia Tallant, Oleg Fedorov, Dean C. Singleton, Catherine M. Rogers, Octovia P. Monteiro, et al. "LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor." Angewandte Chemie 127, no. 21 (April 13, 2015): 6315–19. http://dx.doi.org/10.1002/ange.201501394.
Full textClark, Peter G. K., Lucas C. C. Vieira, Cynthia Tallant, Oleg Fedorov, Dean C. Singleton, Catherine M. Rogers, Octovia P. Monteiro, et al. "LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor." Angewandte Chemie International Edition 54, no. 21 (April 13, 2015): 6217–21. http://dx.doi.org/10.1002/anie.201501394.
Full textShang, Enyuan, Glicella Salazar, Thomas E. Crowley, Xiang Wang, Rocio A. Lopez, Xiangyuan Wang, and Debra J. Wolgemuth. "Identification of unique, differentiation stage-specific patterns of expression of the bromodomain-containing genes Brd2, Brd3, Brd4, and Brdt in the mouse testis." Gene Expression Patterns 4, no. 5 (September 2004): 513–19. http://dx.doi.org/10.1016/j.modgep.2004.03.002.
Full textOttinger, Matthias, Daniel Pliquet, Thomas Christalla, Ronald Frank, James P. Stewart, and Thomas F. Schulz. "The Interaction of the Gammaherpesvirus 68 orf73 Protein with Cellular BET Proteins Affects the Activation of Cell Cycle Promoters." Journal of Virology 83, no. 9 (February 25, 2009): 4423–34. http://dx.doi.org/10.1128/jvi.02274-08.
Full textHagiwara, Masayuki, Atsushi Fushimi, Nami Yamashita, Atrayee Bhattacharya, Hasan Rajabi, Mark D. Long, Yota Yasumizu, Mototsugu Oya, Song Liu, and Donald Kufe. "MUC1-C activates the PBAF chromatin remodeling complex in integrating redox balance with progression of human prostate cancer stem cells." Oncogene 40, no. 30 (June 23, 2021): 4930–40. http://dx.doi.org/10.1038/s41388-021-01899-y.
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