Journal articles on the topic 'Brandt’s voles'

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1

Lou, Mei-Fang, Xue-Ying Zhang, Rong-Shu Fu, and De-Hua Wang. "Effects of dietary fiber content on energetics in nonreproductive and reproductive Brandt’s voles (Lasiopodomys brandtii)." Canadian Journal of Zoology 93, no. 4 (April 2015): 251–58. http://dx.doi.org/10.1139/cjz-2014-0243.

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Food quality can affect many physiological characteristics in small mammals. Reproduction is a highly energy-demanding period especially for the females to produce and feed their offspring. We hypothesized that energy intake was constrained at different levels in nonreproductive and reproductive females and thus they adopted diverse energy strategies in response to diet changes. Here, we tested the effects of low fiber diet (3.5% vs. 12.4%) on energy intake and thermogenesis in nonreproductive and reproductive Brandt’s voles (Lasiopodomys brandtii (Radde, 1861)), a herbivorous species. We found that the voles decreased food intake while keeping a stable digestible energy intake (DEI) in response to the low fiber diet, but DEI was increased in reproductive voles at peak lactation. Uncoupling protein 1 content in brown adipose tissue decreased in nonreproductive voles, but was stable in reproductive voles on the low fiber diet. Litter mass on day 18 of age tended to increase in the low fiber group compared with that in the control group. Our findings demonstrate that the voles have a target intake to maintain energy balance when diet composition changes and energy intake may be constrained at a high level for the reproductive voles to improve their offspring’s fitness.
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2

Song, Hongjie, Yuyang Cheng, Linchao Fan, and Hong Sun. "Expression patterns of clock genes in the kidney of two Lasiopodomys species." Animal Biology 72, no. 1 (February 9, 2022): 51–61. http://dx.doi.org/10.1163/15707563-bja10067.

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Abstract Previous studies showed that the kidney has its own molecular circadian clock expression regulation that maintains the homeostasis of physiological processes. However, limited information is available on the molecular mechanisms of the kidney circadian rhythm in subterranean rodents. Here, we report circadian gene expression in the kidney of subterranean Mandarin voles and the related aboveground Brandt’s voles, reared under 12L:12D (LD) or dark (DD) conditions, respectively. The results showed that the rhythmic genes were represented in Brandt’s voles in higher numbers under LD than DD conditions, but the number of rhythmic genes in Mandarin voles was similar between the two treatment conditions. The gene expression levels at different timepoints all showed reduced results under DD conditions compared with those in the LD cycle in Brandt’s voles, whereas the expression levels of the tested genes at certain Zeitgeber timepoints showed higher results than in the LD cycle in Mandarin voles. The gene expression peak showed chaotic resetting under DD conditions in both voles. We thus suggest that Mandarin and Brandt’s voles have different molecular circadian clock expression adjustment patterns in the kidney as an adaptation to different living environments. Mandarin voles seem to be more adapted to the dark environment, while Brandt’s voles are more dependent on external light conditions.
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Dai, Xin, Ling-Yu Zhou, Ting-Ting Xu, Qiu-Yue Wang, Bin Luo, Yan-Yu Li, Chen Gu, et al. "Reproductive responses of the male Brandt’s vole, Lasiopodomys brandtii (Rodentia: Cricetidae) to tannic acid." Zoologia 37 (November 3, 2020): 1–11. http://dx.doi.org/10.3897/zoologia.37.e52232.

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Tannins are polyphenols that are present in various plants, and potentially contain antioxidant properties that promote reproduction in animals. This study investigated how tannic acid (TA) affects the reproductive parameters of male Brandt’s voles, Lasiopodomys brandtii (Radde, 1861). Specifically, the anti-oxidative level of serum, autophagy in the testis, and reproductive physiology were assessed in males treated with TA from the pubertal stage. Compared to the control, low dose TA enhanced relative testis and epididymis weight and sperm concentration in the epididymis, and significantly increased the level of serum superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px). mRNA levels of autophagy related genes LC3 and Beclin1 decreased significantly with low dose TA compared to the control. However, compared to the control, high dose TA sharply reduced the levels of serum SOD, GSH-Px, CAT, serum testosterone (T), and mRNA level in steroidogenic acute regulatory protein (StAR) in the testis. Both sperm abnormality and mortality increased with high dose TA compared to the control and low dose TA. Collectively, this study demonstrated that TA treatment during puberty had a dose-dependent effect on the reproductive responses of male Brandt’s voles. TA might mediate autophagy in the testis, through both indirect and direct processes. TA mainly affected the reproductive function of male Brandt’s voles by regulating anti-oxidative levels. This study advances our understanding of the mechanisms by which tannins influence reproduction in herbivores.
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Li, Hui, Yun-shang Piao, Zhi-bin Zhang, Christopher M. Hardy, and Lyn A. Hinds. "Molecular cloning and assessment of the immunocontraceptive potential of the zona pellucida subunit 3 from Brandt's vole (Microtus brandti)." Reproduction, Fertility and Development 18, no. 3 (2006): 331. http://dx.doi.org/10.1071/rd05049.

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A full-length cDNA encoding Brandt’s vole (Microtus brandti) zona pellucida glycoprotein subunit 3 (vZP3) was isolated using rapid amplification of cDNA ends–polymerase chain reaction (RACE-PCR). The cDNA contains an open reading frame of 1254 nucleotides encoding a polypeptide of 418 amino acid residues. The deduced amino acid sequence of vZP3 revealed high overall homology with hamster (82.1%), mouse (81.3%) and rat (80.6%). A synthetic vZP3 peptide corresponding to amino acid residues 328–343 was conjugated to keyhole limpet hemocyanin (KLH-vZP3328–343) and used to immunise female Brandt’s voles in order to test the efficacy of this peptide as a contraceptive antigen. High IgG antibody levels to the vZP3328–343 peptide were present in the sera of female voles immunised with KLH-vZP3328–343 and these also cross-reacted to the zona pellucida in ovaries of Brandt’s vole. The fertility of the KLH-vZP3328–343-immunised voles was reduced by 50% compared with controls without evidence of significant ovarian pathology.
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Liu, Min, Xue-Ying Zhang, Chen-Zhu Wang, and De-Hua Wang. "Recruitment of Muscle Genes as an Effect of Brown Adipose Tissue Ablation in Cold-Acclimated Brandt’s Voles (Lasiopodomys brandtii)." International Journal of Molecular Sciences 24, no. 1 (December 25, 2022): 342. http://dx.doi.org/10.3390/ijms24010342.

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Skeletal muscle-based nonshivering thermogenesis (NST) plays an important role in the regulation and maintenance of body temperature in birds and large mammals, which do not contain brown adipose tissue (BAT). However, the relative contribution of muscle-based NST to thermoregulation is not clearly elucidated in wild small mammals, which have evolved an obligate thermogenic organ of BAT. In this study, we investigated whether muscle would become an important site of NST when BAT function is conditionally minimized in Brandt’s voles (Lasiopodomys brandtii). We surgically removed interscapular BAT (iBAT, which constitutes 52%~56% of total BAT) and exposed the voles to prolonged cold (4 °C) for 28 days. The iBAT-ablated voles were able to maintain the same levels of NST and body temperature (~37.9 °C) during the entire period of cold acclimation as sham voles. The expression of uncoupling protein 1 (UCP1) and its transcriptional regulators at both protein and mRNA levels in the iBAT of cold-acclimated voles was higher than that in the warm group. However, no difference was observed in the protein or mRNA levels of these thermogenesis-related markers except for PGC-1α in other sites of BAT (including infrascapular region, neck, and axilla) between warm and cold groups either in sham or iBAT-ablated voles. The iBAT-ablated voles showed higher UCP1 expression in white adipose tissue (WAT) than sham voles during cold acclimation. The expression of sarcolipin (SLN) and sarcoplasmic endoplasmic reticulum Ca2+-dependent adenosine triphosphatase (SERCA) in skeletal muscles was higher in cold than in warm, but no alteration in phospholamban (PLB) and phosphorylated-PLB (P-PLB) was observed. Additionally, there was increased in iBAT-ablated voles compared to that in the sham group in cold. Moreover, these iBAT-ablated voles underwent extensive remodeling of mitochondria and genes of key components related with mitochondrial metabolism. These data collectively indicate that recruitment of skeletal muscle-based thermogenesis may compensate for BAT impairment and suggest a functional interaction between the two forms of thermogenic processes of iBAT and skeletal muscle in wild small mammals for coping cold stress.
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Dai, Xin, Xiao-Feng Sun, Ai-Qin Wang, Wan-Hong Wei, and Sheng-Mei Yang. "Effect of gallic acid on the reproduction of adolescent male Brandt’s voles (Lasiopodomys brandtii)." Canadian Journal of Zoology 99, no. 9 (September 2021): 783–91. http://dx.doi.org/10.1139/cjz-2020-0293.

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Gallic acid (GA), a phenol that is present in various plants, potentially contains antioxidant properties. This study aimed to investigate the effects of GA on the reproduction of adolescent male Brandt’s voles (Lasiopodomys brandtii (Radde, 1861)). Antioxidant levels and apoptosis in the testis, as well as reproductive physiology, were evaluated in adolescent males treated with GA. The results showed that a low dose of GA enhanced relative epididymis mass and the sperm density in the epididymis, increased the mRNA levels of steroidogenic acute regulatory protein in the testis, and reduced the percentages of abnormal and dead sperm. In addition, a low dose of GA significantly increased the levels of superoxide dismutase, catalase, and glutathione peroxidase, and decreased the level of malondialdehyde in the testis, as well as the mRNA and protein levels of the apoptosis-related gene, caspase-3. However, a high dose of GA sharply reduced the mean diameter of the seminiferous tubules compared with a low dose. Collectively, these findings demonstrate that GA treatment during puberty affects the reproductive responses of male Brandt’s voles in a dose-dependent manner by regulating antioxidant levels and apoptosis.
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7

Su, Qian-Qian, Yi Chen, Jiao Qin, Tong-Liang Wang, De-Hua Wang, and Quan-Sheng Liu. "Effects of mifepristone and quinestrol on the fertility of female Brandt’s voles (Lasiopodomys brandtii) in different reproductive phases." Animal Biology 66, no. 2 (2016): 133–43. http://dx.doi.org/10.1163/15707563-00002492.

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Mifepristone and quinestrol are effective drugs for controlling rodent fertility, but their inhibitory effectiveness during premating, early pregnancy, and late pregnancy is unknown. In this study, six groups of eight female Brandt’s voles (Lasiopodomys brandtii) were administered with mifepristone, quinestrol, or a control for three days during premating, early pregnancy, or late pregnancy. In the mifepristone-treated groups, the premating females bred, whereas the early and late pregnant females did not. The reproductive rate, litter size, average body mass at birth, and survival rate of pups did not significantly differ between the mifepristone-treated premating group and the control group. By contrast, quinestrol treatment completely inhibited fertility during the three reproductive phases. In addition, fertility was not completely restored in the second pairing. The reproductive rates were higher for mifepristone, both during early and late pregnancy, than for quinestrol, but both were lower than the control. Thus, mifepristone and quinestrol both inhibited the fertility of female Brandt’s voles at different reproductive periods. These results suggest that these two sterilants could be delivered during the reproductive season of the target pest animal.
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8

Shi, Luye, Xiujuan Li, Zhihong Ji, Zishi Wang, Yuhua Shi, Xiangyu Tian, and Zhenlong Wang. "The reproductive inhibitory effects of levonorgestrel, quinestrol, and EP-1 in Brandt’s vole (Lasiopodomys brandtii)." PeerJ 8 (June 11, 2020): e9140. http://dx.doi.org/10.7717/peerj.9140.

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Background Rodent pests can inflict devastating impacts on agriculture and the environment, leading to significant economic damage associated with their high species diversity, reproductive rates and adaptability. Fertility control methods could indirectly control rodent pest populations as well as limit ecological consequences and environmental concerns caused by lethal chemical poisons. Brandt’s voles, which are common rodent pests found in the grasslands of middle-eastern Inner Mongolia, eastern regions of Mongolia, and some regions of southern Russia, were assessed in the present study. Methods We evaluated the effects of a 2-mg/kg dose of levonorgestrel and quinestrol and a 1:1 mixture of the two (EP-1) on reproductive behavior as well as changes in the reproductive system, reproductive hormone levels, and toxicity in Brandt’s voles. Results Our results revealed that all three fertility control agents can cause reproductive inhibition at a dosage of 2 mg/kg. However, quinestrol caused a greater degree of toxicity, as determined by visible liver damage and reduced expression of the detoxifying molecule CYP1A2. Of the remaining two fertility control agents, EP-1 was superior to levonorgestrel in inhibiting the secretion of follicle-stimulating hormone and causing reproductive inhibition. We believe that these findings could help promote the use of these fertility control agents and, in turn, reduce the use of chemical poisons and limit their detrimental ecological and environmental impacts.
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9

Winters, Ann M., Wilson K. Rumbeiha, Scott R. Winterstein, Amanda E. Fine, B. Munkhtsog, and Graham J. Hickling. "Residues in Brandt’s voles (Microtus brandti) exposed to bromadiolone-impregnated baits in Mongolia." Ecotoxicology and Environmental Safety 73, no. 5 (July 2010): 1071–77. http://dx.doi.org/10.1016/j.ecoenv.2010.02.021.

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10

Xu, Xiaoming, and Zhibin Zhang. "Sex- and age-specific variation of gut microbiota in Brandt’s voles." PeerJ 9 (June 8, 2021): e11434. http://dx.doi.org/10.7717/peerj.11434.

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Background Gut microbiota plays a key role in the survival and reproduction of wild animals which rely on microbiota to break down plant compounds for nutrients. As compared to laboratory animals, wild animals face much more threat of environmental changes (e.g. food shortages and risk of infection). Therefore, studying the gut microbiota of wild animals can help us better understand the mechanisms animals use to adapt to their environment. Methods We collected the feces of Brandt’s voles in the grassland, of three age groups (juvenile, adult and old), in both sexes. We studied the gut microbiota by 16S rRNA sequencing. Results The main members of gut microbiota in Brandt’s voles were Firmicutes, Bacteroidetes and Proteobacteria. As voles get older, the proportion of Firmicutes increased gradually, and the proportion of Bacteroides decreased gradually. The diversity of the microbiota of juveniles is lower, seems like there is still a lot of space for colonization, and there are large variations in the composition of the microbiome between individuals. In adulthood, the gut microbiota tends to be stable, and the diversity is highest. In adult, the abundances of Christensenellaceae and Peptococcus of female were significantly higher than male voles. Conclusions The gut microbiota of Brandt’s vole was influenced by sex and age, probably due to growth needs and hormone levels. Gut microbiota of wild animals were much influenced by their life-history reflected by their age and sex. Future studies will be directed to identify functions of these “wild microbiota” in regulating physiological or behavioral processes of wild animals in different life stage or sexes.
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11

Zhao, Zhi-Jun, and De-Hua Wang. "Short photoperiod influences energy intake and serum leptin level in Brandt’s voles (Microtus brandtii)." Hormones and Behavior 49, no. 4 (April 2006): 463–69. http://dx.doi.org/10.1016/j.yhbeh.2005.10.003.

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Liu, Quan-Sheng, Ji-Yuan Li, and De-Hua Wang. "Ultradian rhythms and the nutritional importance of caecotrophy in captive Brandt’s voles (Lasiopodomys brandtii)." Journal of Comparative Physiology B 177, no. 4 (January 9, 2007): 423–32. http://dx.doi.org/10.1007/s00360-006-0141-4.

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13

Tian, Lin, Yan Chen, Da-Wei Wang, and Xiao-Hui Liu. "Validation of Reference Genes via qRT-PCR in Multiple Conditions in Brandt’s Voles, Lasiopodomys brandtii." Animals 11, no. 3 (March 21, 2021): 897. http://dx.doi.org/10.3390/ani11030897.

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The choice of optimal reference gene is challenging owing to the varied expression of reference genes in different organs, development stages, and experimental treatments. Brandt’s vole (Lasiopodomys brandtii) is an ideal animal to explore the regulatory mechanism of seasonal breeding, and many studies on this vole involve gene expression analysis using quantitative real-time polymerase chain reaction (qRT-PCR). In this study, we used the method of the coefficient of variation and the NormFinder algorithm to evaluate the performance of nine commonly used reference genes Gapdh, Hprt1, β-actin, PPIA, Rpl13a, Tbp, Sdha, Hmbs, and B2M using qRT-PCR in eight different tissues, five developmental stages, and three different photoperiods. We found that all nine genes were not uniformly expressed among different tissues. B2M and Rpl13a were the optimal reference genes for different postnatal development stages in the hypothalamus for males and females, respectively. Under different photoperiods in the hypothalamus, none of the selected genes were suitable as reference genes at 6 weeks postnatal; β-actin and PPIA were the optimal reference genes at 12 weeks postnatal; Hprt1, β-actin, PPIA, Hmbs, and B2M were excellent reference genes at 24 weeks postnatal. The present study provides a useful basis for selecting the appropriate reference gene in Lasiopodomys brandtii.
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Sun, Hong, Kaihong Ye, Denghui Liu, Dan Pan, Shiming Gu, and Zhenlong Wang. "Evolution of Hemoglobin Genes in a Subterranean Rodent Species (Lasiopodomys mandarinus)." Biology 9, no. 5 (May 20, 2020): 106. http://dx.doi.org/10.3390/biology9050106.

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The Mandarin vole (Lasiopodomys mandarinus), a typical subterranean rodent, has undergone hematological adaptations to tolerate the hypoxic/hypercapnic underground environment. Hemoglobin (Hb) genes encode respiratory proteins functioning principally in oxygen binding and transport to various tissues and organs. To investigate the evolution of α- and β-hemoglobin (Hb) in subterranean rodent species, we sequenced Hb genes of the Mandarin vole and the related aboveground Brandt’s vole (L. brandtii). Sequencing showed that in both voles, α-globin was encoded by a cluster of five functional genes in the following linkage order: HBZ, HBA-T1, HBQ-T1, HBA-T2, and HBQ-T2; among these, HBQ-T2 is a pseudogene in both voles. The β-globin gene cluster in both voles also included five functional genes in the following linkage order: HBE, HBE/HBG, HBG, HBB-T1, and HBB-T2. Phylogenetic analysis revealed that the Mandarin vole underwent convergent evolution with its related aboveground species (Brandt’s vole) but not with other subterranean rodent species. Selection pressure analyses revealed that α- and β-globin genes are under strong purifying selection (ω < 1), and branch-site analyses identified positive selection sites on HBAT-T1 and HBB-T1 in different subterranean rodent species. This suggests that the adaptive evolution of these genes enhanced the ability of Hb to store and transport oxygen in subterranean rodent species. Our findings highlight the critical roles of Hb genes in the evolution of hypoxia tolerance in subterranean rodent species.
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Dai, Xin, Jia Shi, Mei Han, Ai Qin Wang, Wan Hong Wei, and Sheng Mei Yang. "Effect of photoperiod and 6-methoxybenzoxazolinone (6-MBOA) on the reproduction of male Brandt’s voles (Lasiopodomys brandtii)." General and Comparative Endocrinology 246 (May 2017): 1–8. http://dx.doi.org/10.1016/j.ygcen.2017.03.003.

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Xu, De-Li, Meng-Meng Xu, and De-Hua Wang. "Effect of temperature on antioxidant defense and innate immunity in Brandt’s voles." Zoological Research 40, no. 4 (2019): 305–16. http://dx.doi.org/10.24272/j.issn.2095-8137.2019.045.

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Bo, Ting-Bei, Xue-Ying Zhang, Jing Wen, Ke Deng, Xiao-Wei Qin, and De-Hua Wang. "The microbiota–gut–brain interaction in regulating host metabolic adaptation to cold in male Brandt’s voles (Lasiopodomys brandtii)." ISME Journal 13, no. 12 (August 27, 2019): 3037–53. http://dx.doi.org/10.1038/s41396-019-0492-y.

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Zhang, Min, and Hongxuan He. "Parasite-mediated selection of major histocompatibility complex variability in wild brandt’s voles (Lasiopodomys brandtii) from Inner Mongolia, China." BMC Evolutionary Biology 13, no. 1 (2013): 149. http://dx.doi.org/10.1186/1471-2148-13-149.

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Liu, Jing, Shuli Huang, Xin Zhang, Guoliang Li, Erdenetuya Batsuren, Wei Lu, Xiaoming Xu, Chen He, Yiran Song, and Zhibin Zhang. "Gut microbiota reflect the crowding stress of space shortage, physical and non-physical contact in Brandt’s voles (Lasiopodomys brandtii)." Microbiological Research 255 (February 2022): 126928. http://dx.doi.org/10.1016/j.micres.2021.126928.

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Pan, Y., L. Xu, Z. Wang, and Z. Zhang. "Expression of Oestrogen Receptor α in the Brain of Brandt’s Voles (Lasiopodomys brandtii ): Sex Differences and Variations During Ovarian Cycles." Journal of Neuroendocrinology 23, no. 10 (September 23, 2011): 926–32. http://dx.doi.org/10.1111/j.1365-2826.2011.02210.x.

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Yin, Baofa, Guoliang Li, Xinrong Wan, Guozhen Shang, Wanhong Wei, and Zhibin Zhang. "Large manipulative experiments reveal complex effects of food supplementation on population dynamics of Brandt’s voles." Science China Life Sciences 60, no. 8 (July 21, 2017): 911–20. http://dx.doi.org/10.1007/s11427-017-9114-9.

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Wu, Ruiyong, Yefeng Huang, Yuan Liu, Qiuyi Shen, Yuxuan Han, Shengmei Yang, and Wanhong Wei. "Repeated predator odor exposure alters maternal behavior of postpartum Brandt’s voles and offspring’s locomotor activity." Behavioural Processes 177 (August 2020): 104143. http://dx.doi.org/10.1016/j.beproc.2020.104143.

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Tang, G. B., J. G. Cui, and D. H. Wang. "Hypothalamic Suppressor-of-Cytokine-Signalling 3 mRNA is Elevated and Pro-Opiomelanocortin mRNA is Reduced During Pregnancy in Brandt’s Voles (Lasiopodomys brandtii )." Journal of Neuroendocrinology 20, no. 9 (September 2008): 1038–44. http://dx.doi.org/10.1111/j.1365-2826.2008.01764.x.

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Liu, Xin-Yu, and De-Hua Wang. "Effects of leptin supplementation to lactating Brandt’s voles (Lasiopodomys brandtii) on the developmental responses of their offspring to a high-fat diet." Journal of Comparative Physiology B 181, no. 6 (March 3, 2011): 829–39. http://dx.doi.org/10.1007/s00360-011-0560-8.

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Wu, Ruiyong, Xueyan Wu, Shan Li, Guran Li, Ziyi Jiang, Haocheng Zhong, Bo Wang, Shengmei Yang, and Wanhong Wei. "Predator odor exposure increases social contact in adolescents and parental behavior in adulthood in Brandt’s voles." Behavioural Processes 186 (May 2021): 104372. http://dx.doi.org/10.1016/j.beproc.2021.104372.

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Li, Xing‐Sheng, and De‐Hua Wang. "Photoperiod and Temperature Can Regulate Body Mass, Serum Leptin Concentration, and Uncoupling Protein 1 in Brandt’s Voles (Lasiopodomys brandtii) and Mongolian Gerbils (Meriones unguiculatus)." Physiological and Biochemical Zoology 80, no. 3 (May 2007): 326–34. http://dx.doi.org/10.1086/513189.

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Zhang, Xue-Ying, Yu-Lian Li, and De-Hua Wang. "Large litter size increases maternal energy intake but has no effect on UCP1 content and serum-leptin concentrations in lactating Brandt’s voles (Lasiopodomys brandtii)." Journal of Comparative Physiology B 178, no. 5 (February 19, 2008): 637–45. http://dx.doi.org/10.1007/s00360-008-0255-y.

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Li, Guoliang, Baofa Yin, Xinrong Wan, Wanhong Wei, Guiming Wang, Charles J. Krebs, and Zhibin Zhang. "Successive sheep grazing reduces population density of Brandt’s voles in steppe grassland by altering food resources: a large manipulative experiment." Oecologia 180, no. 1 (October 7, 2015): 149–59. http://dx.doi.org/10.1007/s00442-015-3455-7.

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Wu, Ruiyong, Shan Li, Yefeng Huang, Jinyue Pang, Yongjian Cai, Xinyue Zhang, Tianyi Jiang, Shengmei Yang, and Wanhong Wei. "Postpartum maternal exposure to predator odor alters offspring antipredator behavior, basal HPA axis activity and immunoglobulin levels in adult Brandt’s voles." Behavioural Brain Research 416 (January 2022): 113532. http://dx.doi.org/10.1016/j.bbr.2021.113532.

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Liu, Xiao Hui, Ling Fen Yue, Da Wei Wang, Ning Li, and Lin Cong. "Inbreeding Avoidance Drives Consistent Variation of Fine-Scale Genetic Structure Caused by Dispersal in the Seasonal Mating System of Brandt’s Voles." PLoS ONE 8, no. 3 (March 14, 2013): e58101. http://dx.doi.org/10.1371/journal.pone.0058101.

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Li, Qilin, and Li Zhang. "Parent–offspring recognition in Brandt's voles, Lasiopodomys brandti." Animal Behaviour 79, no. 4 (April 2010): 797–801. http://dx.doi.org/10.1016/j.anbehav.2009.12.001.

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Tang, Gang-Bin, Jian-Guo Cui, and De-Hua Wang. "Role of hypoleptinemia during cold adaptation in Brandt's voles (Lasiopodomys brandtii)." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 297, no. 5 (November 2009): R1293—R1301. http://dx.doi.org/10.1152/ajpregu.00185.2009.

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Brandt's voles Lasiopodomys brandtii exhibit large increases in nonshivering thermogenesis to cope with chronic cold exposure, resulting in compensatory hyperphagia and fat mobilization. These physiological events are accompanied by a remarkable reduction in serum leptin levels. However, the role of hypoleptinemia in cold adaptation in this species is still unknown. In the present study, we tested the hypothesis that hypoleptinemia contributes to increases in food intake and brown adipose tissue (BAT) thermogenesis by modifying hypothalamic neuropeptides in cold-exposed Brandt's voles. Adult male voles were transferred to 5°C for 28 days. Accompanied by a decrease in serum leptin levels, hypothalamic agouti-related protein (AgRP) mRNA levels were significantly increased, but there were no changes in the long form of leptin receptor (Ob-Rb), suppressor of cytokine signaling 3 (SOCS3), neuropeptide Y (NPY) mRNA, proopiomelanocortin (POMC), and cocaine- and amphetamine-regulated peptide (CART) mRNA levels in the hypothalamus. When cold-exposed voles were returned to warm (23°C) for 28 days, body mass, food intake, serum leptin, and AgRP mRNA were restored to control levels. Leptin administration in cold-exposed voles decreased food intake as well as hypothalamic AgRP mRNA levels. There were no significant effects of leptin administration on hypothalamic Ob-Rb, SOCS3, NPY, POMC, CART mRNA, and uncoupling protein 1 levels under cold conditions. These results suggest that hypoleptinemia partially contributes to cold-induced hyperphagia, which might involve the elevation of hypothalamic AgRP gene expression.
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Liu, He, De-Hua Wang, and Zu-Wang Wang. "ENERGY REQUIREMENTS DURING REPRODUCTION IN FEMALE BRANDT'S VOLES (MICROTUS BRANDTII)." Journal of Mammalogy 84, no. 4 (November 2003): 1410–16. http://dx.doi.org/10.1644/brg-030.

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Hegab, Ibrahim M., Yajuan Jin, Manhong Ye, Aiqin Wang, Baofa Yin, Shengmei Yang, and Wanhong Wei. "Defensive responses of Brandt's voles (Lasiopodomys brandtii) to stored cat feces." Physiology & Behavior 123 (January 2014): 193–99. http://dx.doi.org/10.1016/j.physbeh.2013.10.030.

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Hegab, Ibrahim M., Guoshen Shang, Manhong Ye, Yajuan Jin, Aiqin Wang, Baofa Yin, Shengmei Yang, and Wanhong Wei. "Defensive responses of Brandt's voles (Lasiopodomys brandtii) to chronic predatory stress." Physiology & Behavior 126 (March 2014): 1–7. http://dx.doi.org/10.1016/j.physbeh.2013.12.001.

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Chen, Yan, Lan Liu, Zhengguang Li, Dawei Wang, Ning Li, Ying Song, Cong Guo, and Xiaohui Liu. "Molecular cloning and characterization of kiss1 in Brandt's voles ( Lasiopodomys brandtii )." Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 208-209 (June 2017): 68–74. http://dx.doi.org/10.1016/j.cbpb.2017.04.006.

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Zhi-long, Liu, Liu Zhong-min, and Sun Ru-yong. "Seasonal Water Turnover Rates of Free-Living Brandt's Voles Microtus brandti." Physiological Zoology 65, no. 1 (January 1992): 215–25. http://dx.doi.org/10.1086/physzool.65.1.30158247.

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Yu, Xiaodong, Ruyong Sun, and Jiming Fang. "Effect of kinship on social behaviors in Brandt's voles ( Microtus brandti )." Journal of Ethology 22, no. 1 (January 1, 2004): 17–22. http://dx.doi.org/10.1007/s10164-003-0097-8.

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WANG, DENG, and DAZHAO SHI. "Isolation and characterization of polymorphic microsatellite loci from Brandt's voles (Lasiopodomys brandtii)." Molecular Ecology Notes 7, no. 4 (December 20, 2006): 671–73. http://dx.doi.org/10.1111/j.1471-8286.2006.01673.x.

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Cai, Xiao-Quan, Ming Yang, Wen-Qin Zhong, and De-Hua Wang. "Humoral immune response suppresses reproductive physiology in male Brandt's voles (Lasiopodomys brandtii)." Zoology 112, no. 1 (January 2009): 69–75. http://dx.doi.org/10.1016/j.zool.2008.04.006.

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Li, Xing-Sheng, and De-Hua Wang. "Suppression of thermogenic capacity during reproduction in primiparous brandt's voles (Microtus brandtii)." Journal of Thermal Biology 30, no. 6 (August 2005): 431–36. http://dx.doi.org/10.1016/j.jtherbio.2005.05.005.

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ZHAO, Meirong, Ming LIU, Dong LI, Xinrong WAN, Lyn A. HINDS, Yanling WANG, and Zhibin ZHANG. "Anti-fertility effect of levonorgestrel and quinestrol in Brandt's voles (Lasiopodomys brandtii )." Integrative Zoology 2, no. 4 (December 2007): 260–68. http://dx.doi.org/10.1111/j.1749-4877.2007.00059.x.

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Zhang, Xue-Ying, and De-Hua Wang. "Metabolic adaptations during pregnancy and lactation in primiparous Brandt's voles (Lasiopodomys brandtII)." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 148, no. 4 (November 2008): 473. http://dx.doi.org/10.1016/j.cbpc.2008.10.093.

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Lu, Qin, Wen-Qin Zhong, and De-Hua Wang. "Individual variation and repeatability of the aerobic performance in Brandt's voles (Lasiopodomys brandtii)." Journal of Thermal Biology 32, no. 7-8 (October 2007): 413–20. http://dx.doi.org/10.1016/j.jtherbio.2007.08.001.

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Li, Xing-Sheng, and De-Hua Wang. "Regulation of body weight and thermogenesis in seasonally acclimatized Brandt's voles (Microtus brandti)." Hormones and Behavior 48, no. 3 (September 2005): 321–28. http://dx.doi.org/10.1016/j.yhbeh.2005.04.004.

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Zhang, X. Y., and D. H. Wang. "Thermogenesis, food intake and serum leptin in cold-exposed lactating Brandt's voles Lasiopodomys brandtii." Journal of Experimental Biology 210, no. 3 (February 1, 2007): 512–21. http://dx.doi.org/10.1242/jeb.02659.

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Hegab, Ibrahim M., Aiqin Wang, Baofa Yin, Shengmei Yang, and Wei Wanhong. "Behavioral and neuroendocrine response of Brandt's voles, Lasiopodomys brandtii, to odors of different species." European Journal of Wildlife Research 60, no. 2 (December 28, 2013): 331–40. http://dx.doi.org/10.1007/s10344-013-0790-z.

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Cui, J. G., G. B. Tang, and D. H. Wang. "Hypothalamic neuropeptides, not leptin sensitivity, contributes to the hyperphagia in lactating Brandt's voles, Lasiopodomys brandtii." Journal of Experimental Biology 214, no. 13 (June 8, 2011): 2242–47. http://dx.doi.org/10.1242/jeb.054056.

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Lu, Q., W. Q. Zhong, and D. H. Wang. "Effects of photoperiod history on body mass and energy metabolism in Brandt's voles (Lasiopodomys brandtii)." Journal of Experimental Biology 210, no. 21 (November 1, 2007): 3838–47. http://dx.doi.org/10.1242/jeb.010025.

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Zhang, Xue-Ying, and De-Hua Wang. "Energy intake, thermogenic capacity and serum leptin in cold-exposed pregnant Brandt's voles (Lasiopodomys brandtII)." Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 148, no. 4 (November 2008): 473. http://dx.doi.org/10.1016/j.cbpc.2008.10.094.

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