Academic literature on the topic 'Brain irradiation'

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Journal articles on the topic "Brain irradiation"

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Shirato, Hiroki, Akio Takamura, Masayoshi Tomita, et al. "Stereotactic irradiation without whole-brain irradiation for single brain metastasis." International Journal of Radiation Oncology*Biology*Physics 37, no. 2 (1997): 385–91. http://dx.doi.org/10.1016/s0360-3016(96)00488-9.

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Feng, Xi, Sonali Gupta, David Chen, et al. "SCIDOT-04. REPLACEMENT OF MICROGLIA BY BRAIN-ENGRAFTED MACROPHAGES PREVENTS MEMORY DEFICITS AFTER THERAPEUTIC WHOLE-BRAIN IRRADIATION." Neuro-Oncology 21, Supplement_6 (2019): vi273. http://dx.doi.org/10.1093/neuonc/noz175.1145.

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Abstract Microglia have a distinct origin compared to blood circulating myeloid cells. Under normal physiological conditions, microglia are maintained by self-renewal, independent of hematopoietic progenitors. Following genetic or pharmacologic depletion, newborn microglia derive from the local residual pool and quickly repopulate the entire brain. The depletion of brain resident microglia during therapeutic whole-brain irradiation fully prevents irradiation-induced synaptic loss and recognition memory deficits but the mechanisms driving these protective effects are unknown. Here, we demonstra
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Feng, Xi, Sonali Gupta, David Chen, et al. "EXTH-08. REPLACEMENT OF MICROGLIA BY BRAIN-ENGRAFTED MACROPHAGES PREVENTS MEMORY DEFICITS AFTER THERAPEUTIC WHOLE-BRAIN IRRADIATION." Neuro-Oncology 21, Supplement_6 (2019): vi83—vi84. http://dx.doi.org/10.1093/neuonc/noz175.342.

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Abstract Microglia have a distinct origin compared to blood circulating myeloid cells. Under normal physiological conditions, microglia are maintained by self-renewal, independent of hematopoietic progenitors. Following genetic or pharmacologic depletion, newborn microglia derive from the local residual pool and quickly repopulate the entire brain. The depletion of brain resident microglia during therapeutic whole-brain irradiation fully prevents irradiation-induced synaptic loss and recognition memory deficits but the mechanisms driving these protective effects are unknown. Here, we demonstra
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Yuan, Hong, Judith N. Rivera, Jonathan E. Frank, Jonathan Nagel, Colette Shen, and Sha X. Chang. "Mini-Beam Spatially Fractionated Radiation Therapy for Whole-Brain Re-Irradiation—A Pilot Toxicity Study in a Healthy Mouse Model." Radiation 4, no. 2 (2024): 125–41. http://dx.doi.org/10.3390/radiation4020010.

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For patients with recurrent brain metastases, there is an urgent need for a more effective and less toxic treatment approach. Accumulating evidence has shown that spatially fractionated radiation therapy (SFRT) is able to provide a significantly higher therapeutic ratio with lower toxicity compared to conventional radiation using a uniform dose. The purpose of this study was to explore the potential low toxicity benefit of mini-beam radiotherapy (MBRT), a form of SFRT, for whole-brain re-irradiation in a healthy mouse model. Animals first received an initial 25 Gy of uniform whole-brain irradi
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OKAMOTO, Shinichiro, Hajime HANDA, Junkoh YAMASHITA, Yasuhiko TOKURIKI, and Mitsuyuki ABE. "Post-irradiation Brain Tumors." Neurologia medico-chirurgica 25, no. 7 (1985): 528–33. http://dx.doi.org/10.2176/nmc.25.528.

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Wurm, R. E., L. Schlenger, A. Kaiser, et al. "Brain metastases — Radiosurgery or whole brain irradiation?" European Journal of Cancer 35 (September 1999): S129. http://dx.doi.org/10.1016/s0959-8049(99)80896-x.

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Natsuko, Kondo, Sakurai Yoshinori, Takayuki Kajihara, et al. "ET-13 CONTROL OF ACTIVATED MICROGLIA THROUGH P2X4 RECEPTOR IN RADIATION BRAIN NECROSIS." Neuro-Oncology Advances 1, Supplement_2 (2019): ii10. http://dx.doi.org/10.1093/noajnl/vdz039.043.

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Abstract INTRODUCTION Brain radiation necrosis (RN) is severe adverse event after radiation therapy for brain tumor patients, especially in case of re-irradiation. Although corticosteroids or vitamin E, etc. are clinically used for RN, the effect is limited and underlying mechanism is to be cleared. Therefore, we established RN mouse model with irradiating right hemisphere of mouse brain using proton beam at dose of 60 Gy [Kondo et al., 2015]. In this study, we investigated change of phospholipids and lipid mediators after irradiation using this RN model in correlation with microglia activatio
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Crvenkova, S., and C. Tolevska. "314 Partial brain irradiation (PBI) or whole brain irradiation (WBI), the justified solution." European Journal of Cancer Supplements 1, no. 5 (2003): S96. http://dx.doi.org/10.1016/s1359-6349(03)90347-8.

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Romano, Mariele, Alberto Bravin, Alberto Mittone, et al. "A Multi-Scale and Multi-Technique Approach for the Characterization of the Effects of Spatially Fractionated X-ray Radiation Therapies in a Preclinical Model." Cancers 13, no. 19 (2021): 4953. http://dx.doi.org/10.3390/cancers13194953.

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The purpose of this study is to use a multi-technique approach to detect the effects of spatially fractionated X-ray Microbeam (MRT) and Minibeam Radiation Therapy (MB) and to compare them to seamless Broad Beam (BB) irradiation. Healthy- and Glioblastoma (GBM)-bearing male Fischer rats were irradiated in-vivo on the right brain hemisphere with MRT, MB and BB delivering three different doses for each irradiation geometry. Brains were analyzed post mortem by multi-scale X-ray Phase Contrast Imaging–Computed Tomography (XPCI-CT), histology, immunohistochemistry, X-ray Fluorescence (XRF), Small-
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Lissoni, P., S. Meregalli, S. Curreri, et al. "Brain Irradiation-Induced Lymphocytosis Predicts Response in Cancer Patients with Brain Metastases." International Journal of Biological Markers 23, no. 2 (2008): 111–14. http://dx.doi.org/10.1177/172460080802300207.

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Lymphocytopenia is one of the main toxicities of radiotherapy and its severity is related to the irradiation dose. The occurrence of lymphocytopenia depends on the body site of radiotherapy; it is most pronounced with pelvic irradiation, whereas the effect of brain irradiation on the lymphocyte count is to be elucidated. This preliminary study was performed to evaluate changes in lymphocyte number occurring during brain irradiation in cancer patients with brain metastases. The study included 50 patients who received brain radiotherapy for single or multiple brain metastases at a total dose of
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Dissertations / Theses on the topic "Brain irradiation"

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Madhoo, Jitesh. "Continuous low dose rate irradiation of the rat brain." Doctoral thesis, University of Cape Town, 1999. http://hdl.handle.net/11427/26785.

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The reported median survival time for patients who are diagnosed with high grade astrocytomas and who undergo postoperative radiotherapy is of the order of 24 to 40 weeks. The course of radiotherapy administered to these patients takes up a considerable portion of their expected survival time. Therefore, any means of reducing the treatment time may contribute to an enhanced quality of life for these patients. A potentially useful method for the reduction of the treatment time may be achieved with the use of continuous low dose rate external beam radiotherapy, where the treatment is administere
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Wedlock, Pauline Margaret. "Behavioural effects of low intensity laser irradiation of the rodent brain." Thesis, University of Ulster, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339311.

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Lee, Won Hee. "Molecular mechanisms of radiation-induced brain injury." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/77254.

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Radiation therapy has been most commonly used modality in the treatment of brain tumors. About 200,000 patients with brain tumors are treated with either partial large field or whole brain irradiation every year in the United States. The use of radiation therapy for treatment of brain tumor, however, can subsequently lead to devastating functional deficits several months to years after treatment. Unfortunately, there are no known successful treatments and effective strategies for mitigating radiation-induced brain injury. In addition, the specific mechanisms by which irradiation causes brain i
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Pike, G. Bruce (Gilbert Bruce). "Three dimensional stereotaxic intracavitary and external beam isodose calculation for treatment of brain lesions." Thesis, McGill University, 1986. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=65439.

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Pontén, Emeli. "Astrocyte response after irradiation of the juvenile brain : -­‐ a study on C57BL/6 strain mice (p21)." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-55163.

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Kasahara, Seiko. "Hyperintense dentate nucleus on unenhanced T1-weighted MR images is associated with a history of brain irradiation." Kyoto University, 2011. http://hdl.handle.net/2433/151912.

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Spoudeas, Helen Alexandra. "The evolution of growth hormone neurosecretory disturbance during high dose cranial irradiation and chemotherapy for childhood brain tumours." Thesis, Queen Mary, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261873.

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Pham, Thao Nguyen. "Biοmathematical insights intο radiatiοn-induced systemic immune effects in brain and head & neck cancer using preclinical and clinical mοdels". Electronic Thesis or Diss., Normandie, 2024. http://www.theses.fr/2024NORMC407.

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La radiothérapie, bien qu'efficace contre les tumeurs, peut perturber le système immunitaire et provoquer une lymphopénie, ce qui impacte négativement les résultats du traitement. Des radiothérapies plus ciblées, telles que la protonthérapie, offrent des perspectives prometteuses pour réduire la lymphopénie. Au-delà de la lymphopénie, les sous-populations de leucocytes dans les lignées lymphoïde et myéloïde ont un impact significatif sur la réponse immunitaire antitumorale. Cette thèse examine l'impact de l'irradiation cérébrale sur le système immunitaire en utilisant la modélisation biomathém
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Martigne, Patrick. "Neuropathologie radio-induite : des effets précoces aux séquelles tardives : études comportementales et métaboliques chez le rat après irradiation globale sublétale." Grenoble, 2010. http://www.theses.fr/2010GRENS012.

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Le dogme relatif à la radiorésistance du Système Nerveux Central (SNC) a vécu. Les progrès en neurosciences permettent aujourd'hui de reconsidérer les dysfonctionnements cognitifs radio-induits observés au décours des radiothérapies ou après un accident d'irradiation, et d'envisager des moyens diagnostiques et thérapeutiques adaptés. Nous avons développé un modèle Rat afin d'étudier les effets d'une irradiation gamma corps entier à dose sublétale (4,5 Gy). Celle-ci induit des troubles de l'apprentissage et de la mémorisation d'une tâche en cours d'acquisition durant le premier mois – lesquels
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Dwiri, Fatima azzahra. "Impacts de l'irradiation ciblée sur le tissu cérébral et les déficits cognitifs : études multiparamétriques et longitudinales chez le rat." Electronic Thesis or Diss., Normandie, 2023. http://www.theses.fr/2023NORMC411.

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Bien que la radiothérapie, traitement incontournable en neuro-oncologie, améliore la survie des patients, elle affecte de manière considérable le tissu cérébral sain avoisinant la tumeur conduisant à des déficits cognitifs qui sont retrouvés chez 50 à 90 % des patients. Les avancées technologiques réalisées lors de la dernière décennie ont permis de concevoir de nouvelles techniques d’irradiation avec des propriétés balistiques prometteuses. Cependant, leurs intérêts pour prévenir la radiotoxicité cérébrale reste à démontrer, en s’appuyant notamment sur des recherches précliniques pour lesquel
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Books on the topic "Brain irradiation"

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Wedlock, Pauline Margaret. Behavioural effects of low intesity laser irradiation of the rodent brain. The Author], 1995.

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International Commission on Radiological Protection. Committee 1., ed. Developmental effects of irradiation on the brain of the embryo and fetus: A report. Pergamon Press, 1986.

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Shvarts, Shifra, and Siegal Sadetzki. Ringworm and Irradiation. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780197568965.001.0001.

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The practice of using x-rays for the medical treatment of benign diseases began in the 1920s and peaked in the 1940s and 1950s. Radiation therapy was considered good medical practice during the first decades of the 20th century and was very effective at controlling and eliminating ringworm (tinea capitis), an epidemic that was spread mainly among children. Results were often immediate. In the United States, Canada, Europe, Australia, the Middle East, and North Africa, hundreds of thousands of children were treated with radiation therapy for ringworm of the scalp. X-ray treatment gradually came
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Jo, Jasmin, and David Schiff. Brain Metastases. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0141.

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In the past, detection of brain metastases signaled the conclusion of aggressive systemic treatment and shifted the focus of care toward palliation. The median survival for patients with single brain metastasis without brain-directed treatment is about a month. Whole brain radiation therapy was the traditional palliative treatment utilized, offering an additional 2 to 5 months. More recently, in addition to whole brain irradiation, the roles of surgery, stereotactic radiosurgery, chemotherapy, and targeted therapies in the definitive management of brain metastases have been investigated in num
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Thorne, M. ICRP Publication 49: Developmental Effects of Irradiation on the Brain of the Embryo and Fetus. Elsevier Science & Technology, 1987.

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Developmental effects of irradiation on the brain of the embryo and fetus: A report of a task group of committee 1 of the International Commission on Radiological Protection : adopted by the Commission in July 1986. Pergamon for the International Commission on Radiological Protection, 1986.

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Jalali, Rakesih, Patrick Y. Wen, and Takamitsu Fujimaki. Meningiomas. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199651870.003.0011.

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Meningiomas are the most common type of primary brain tumour, comprising approximately one-third of all intracranial neoplasms. It is therefore important for all neuro-oncologists to understand the biology and optimal managements of these tumours. The majority of meningiomas are World Health Organization grade I benign tumours, but grade II (atypical) or grade III (anaplastic) tumours are not uncommon. Total surgical removal is the standard of care but may not be feasible if the tumour involves critical structures such as cranial nerves or important blood vessels. Conventional radiation therap
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Hodgkiss, Andrew. Biological Psychiatry of Cancer and Cancer Treatment. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198759911.001.0001.

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As long-term cancer survival becomes a widely shared experience, the quality of life of people living with and beyond a cancer diagnosis is increasingly important. Optimizing the prevention and treatment of any psychiatric consequences of certain tumours and treatments is now central to high-quality cancer care. This book—a rather original addition to the oncology and psycho-oncology literature—aims to equip oncology clinicians with the knowledge to more expertly prevent, detect, and manage the ‘organic’ psychiatric disorders experienced by people with cancer. It will also serve as a valuable
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Book chapters on the topic "Brain irradiation"

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Nieder, Carsten, Anca L. Grosu, and Minesh P. Mehta. "Brain Metastases." In Re-irradiation: New Frontiers. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/174_2010_66.

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Gains, Jennifer E., and Susan C. Short. "Brain Tumors." In Re-irradiation: New Frontiers. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/174_2010_68.

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Nieder, Carsten, Anca L. Grosu, and Minesh P. Mehta. "Brain Metastases." In Re-Irradiation: New Frontiers. Springer International Publishing, 2016. http://dx.doi.org/10.1007/174_2016_58.

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Palmer, Joshua D., Colin Champ, Susan C. Short, and Shannon E. Fogh. "Brain Tumours." In Re-Irradiation: New Frontiers. Springer International Publishing, 2016. http://dx.doi.org/10.1007/174_2016_66.

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Alesch, François, R. Hawliczek, and W. Th Koos. "Interstitial Irradiation of Brain Metastases." In Stereotactic Neuro-Radio-Surgery. Springer Vienna, 1995. http://dx.doi.org/10.1007/978-3-7091-9399-0_7.

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Korinthenberg, R. "Irradiation-Induced Brain Dysfunction in Children." In Acute and Long-Term Side-Effects of Radiotherapy. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-84892-6_17.

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Tarbell, Nancy J., James Wallman, Patricia Eifel, and J. Robert Cassady. "Results of definitive irradiation for optic gliomas." In Biology of Brain Tumour. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2297-9_50.

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Oppel, F., H. W. Pannek, J. Voges, and M. Brock. "Interstitial Irradiation of Inoperable Brain Stem Tumors." In Surgery in and around the Brain Stem and the Third Ventricle. Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71240-1_69.

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Lafuente, J. V., J. Cervós-Navarro, and E. Gutierrez Argandoña. "Evaluation of BBB Damage in an UV Irradiation Model by Endogenous Protein Tracers." In Brain Edema IX. Springer Vienna, 1994. http://dx.doi.org/10.1007/978-3-7091-9334-1_37.

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Salcman, Michael, Wilfred Sewchand, Pradip P. Amin, and Edwin H. Bellis. "Technique and preliminary results of interstitial irradiation for recurrent glial tumors." In Biology of Brain Tumour. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2297-9_49.

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Conference papers on the topic "Brain irradiation"

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Filatov, P. V., E. S. Polovnikov, K. Yu Orlov, et al. "Multiple brain metastases irradiation with Eleka Axesse stereotactic system." In PHYSICS OF CANCER: INTERDISCIPLINARY PROBLEMS AND CLINICAL APPLICATIONS: Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17). Author(s), 2017. http://dx.doi.org/10.1063/1.5001597.

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Moore, Elizabeth, Mitra Kooshki, Lance Miller, and Mike Robbins. "Abstract 78: Fractionated whole brain irradiation modulates Homer1a expression in a brain region specific manner." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-78.

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Ojeda, Abril Damaris Iglesias, Monserrat Llaguno Munive, Efrén Hernández Ramirez, and Luis Alberto Medina Velázquez. "Dosimetry in fractionated irradiation of rat brain to evaluate radiobiological response." In PROCEEDINGS OF THE XVI MEXICAN SYMPOSIUM ON MEDICAL PHYSICS. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0051374.

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Kolesnikova, Inna, Natalia Budennaya, Yurii Severiukhin, et al. "THE EFFECT OF PROTON IRRADIATION ON THE MORPHOFUNCTIONAL STATE OF THE RAT BRAIN." In XV International interdisciplinary congress "Neuroscience for Medicine and Psychology". LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m430.sudak.ns2019-15/226-227.

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Stoica, Roberta, Mihai Radu, and Beatrice Mihaela Radu. "Functional changes in brain microvascular endothelial cells upon low-energy accelerated proton-irradiation." In RAD Conference. RAD Centre, 2021. http://dx.doi.org/10.21175/rad.abstr.book.2021.32.17.

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Moskaleva, Elizaveta, Alla Rodina, Alexander Zhirnik, et al. "STATE OF BRAIN CELLS AND COGNITIVE FUNCTIONS IN MICE AFTER NEUTRON HEAD IRRADIATION." In XVIII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2022. http://dx.doi.org/10.29003/m2854.sudak.ns2022-18/238-239.

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Chernikova, Sophia, G.-One Ahn, Shie-Chau Liu, Jason Stafford, and J. Martin Brown. "Abstract C291: Targeting SDF-1 (CXCL12) pathway to inhibit the recurrence of breast cancer brain metastases after whole-brain irradiation." In Abstracts: AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics--Oct 19-23, 2013; Boston, MA. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1535-7163.targ-13-c291.

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Momiyama, Masashi, Yukihiko Hiroshima, Atsushi Suetsugu, et al. "Abstract 5546: UVC irradiation inhibits superficial tumor growth in the brain of nude mice." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-5546.

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Xiao, Xue-Chang, Jia-Zheng Dong, Xiao-Fan Chu, et al. "SPECT study of low intensity He-Ne laser intravascular irradiation therapy for brain infarction." In Third International Conference on Photonics and Imaging in Biology and Medicine, edited by Qingming Luo, Valery V. Tuchin, Min Gu, and Lihong V. Wang. SPIE, 2003. http://dx.doi.org/10.1117/12.546102.

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Kopaeva, Marina, Anton Cherepov, Mikhail Nesterenko, and Irina Zarayskaya. "PROTECTIVE EFFECT OF LACTOFERRIN ON MOUSE BRAIN CELLS AFTER GAMMA IRRADIATION OF THE HEAD." In XVIII INTERNATIONAL INTERDISCIPLINARY CONGRESS NEUROSCIENCE FOR MEDICINE AND PSYCHOLOGY. LCC MAKS Press, 2022. http://dx.doi.org/10.29003/m2796.sudak.ns2022-18/176-177.

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Reports on the topic "Brain irradiation"

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Manley, N. B., J. I. Fabrikant, and E. L. Alpen. Cell and tissue kinetics of the subependymal layer in mouse brain following heavy charged particle irradiation. Office of Scientific and Technical Information (OSTI), 1988. http://dx.doi.org/10.2172/7191328.

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