Relevant bibliographies by topics / Boswellic acid

Academic literature on the topic 'Boswellic acid'

Author: Grafiati
Published: 4 June 2021
Last updated: 19 February 2022

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Journal articles on the topic "Boswellic acid"

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Ota, Masahiro, and Peter J. Houghton. "Boswellic Acids with Acetylcholinesterase Inhibitory Properties from Frankincense." Natural Product Communications 3, no. 1 (January 2008): 1934578X0800300. http://dx.doi.org/10.1177/1934578x0800300105.

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Frankincense, a gum resin secreted from barks of Boswellia species, is reputed in Arabian folk medicine to improve the memory. In this study, the acetylcholinesterase inhibitory effect of extracts of frankincense and their constituents were investigated. The ethyl acetate soluble fraction from methanol extracts showed the greatest inhibition of acetylcholinesterase. Bioassay-guided fractionation was carried out to isolate several boswellic acids, and their structures were determined spectroscopically. The boswellic acids showing the most inhibitory activity on acetylcholinesterase were 11α-hydroxy-β-boswellic acid (1) and 11-keto-β-boswellic acid (5), whilst others isolated i.e. 3α-acetyl-11-keto-β-boswellic acid (2), 3α-acetyl-11α-hydroxy-β-boswellic acid (3), 11α-methoxy-β-boswellic acid (4), β-boswellic acid (6) and α-boswellic acid (7) were inactive. Acetylcholinesterase inhibitory activity appears to be associated with the presence of either the free hydroxyl group or keto group at C-11 and of the free hydroxyl group at C-3 in the ursane skeleton.
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Schmiech, Michael, Judith Ulrich, Sophia Johanna Lang, Berthold Büchele, Christian Paetz, Alexis St-Gelais, Tatiana Syrovets, and Thomas Simmet. "11-Keto-α-Boswellic Acid, a Novel Triterpenoid from Boswellia spp. with Chemotaxonomic Potential and Antitumor Activity against Triple-Negative Breast Cancer Cells." Molecules 26, no. 2 (January 12, 2021): 366. http://dx.doi.org/10.3390/molecules26020366.

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Boswellic acids, and particularly 11-keto-boswellic acids, triterpenoids derived from the genus Boswellia (Burseraceae), are known for their anti-inflammatory and potential antitumor efficacy. Although boswellic acids generally occur as α-isomers (oleanane type) and β-isomers (ursane type), 11-keto-boswellic acid (KBA) was found only as the β-isomer, β-KBA. Here, the existence and natural occurrence of the respective α-isomer, 11-keto-α-boswellic acid (α-KBA), is demonstrated for the first time. Initially, α-KBA was synthesized and characterized by high-resolution mass spectrometry (HR-MS) and nuclear magnetic resonance (NMR) spectroscopy, and a highly selective, sensitive, and accurate high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS) method was developed by Design of Experiments (DoE) using a pentafluorophenyl stationary phase. This method allowed the selective quantification of individual 11-keto-boswellic acids and provided evidence for α-KBA in Boswellia spp. oleogum resins. The contents of α-KBA as well as further boswellic acids and the composition of essential oils were used to chemotaxonomically classify 41 Boswellia oleogum resins from 9 different species. Moreover, α-KBA exhibited cytotoxicity against three treatment-resistant triple-negative breast cancer (TNBC) cell lines in vitro and also induced apoptosis in MDA-MB-231 xenografts in vivo. The respective β-isomer and the acetylated form demonstrate higher cytotoxic efficacies against TNBC cells. This provides further insights into the structure-activity relationship of boswellic acids and could support future developments of potential anti-inflammatory and antitumor drugs.
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Wolfram, Ratna Kancana, Anja Barthel-Niesen, Renate Schäfer, Lucie Heller, Ahmed Al-Harrasi, and René Csuk. "Synthesis and cytotoxic screening of beta-boswellic acid derivatives." Mediterranean Journal of Chemistry 6, no. 4 (July 15, 2017): 142–64. http://dx.doi.org/10.13171/mjc64/01707151548-csuk.

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Beta-boswellic acids are triterpenoids being generic to the plants of genus boswellia. Although they were shown to exhibit different biological activities, the cytotoxic potential of b-boswellic acid derivatives remained by and large unexploited. To expand the potential of these compounds we developed simple procedures for the interconversion of the most important b-boswellic acids 1-4 and prepared several other derivatives 5-48. These compounds were screened for their cytotoxic activity in sulforhodamine B assays employing several human tumor cell lines and nonmalignant mouse fibroblasts. One of these compounds, a difluoromethylester of 3-O-acetyl-11-keto-beta-boswellic acid 23, was cytotoxic for human breast adenocarcinoma cells MCF-7 (EC50 = 6.5 mM) while being significantly less cytotoxic for the mouse fibroblasts.
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Badria, Farid A., Botros R. Mikhaeil, Galal T. Maatooq, and Mohamed M. A. Amer. "Immunomodulatory Triterpenoids from the Oleogum Resin of Boswellia carterii Birdwood." Zeitschrift für Naturforschung C 58, no. 7-8 (August 1, 2003): 505–16. http://dx.doi.org/10.1515/znc-2003-7-811.

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Abstract The immunomodulatory bioassay-guided fractionation of the oleogum resin of frankincense (Boswellia carterii Bird wood) resulted in the isolation and identification of 9 compounds; palmitic acid and eight triterpenoids belonging to lupane, ursane, oleanane, and tirucallane skeleta were isolated form the resin. These triterpenoids are lupeol, β-boswellic acid, 11-keto-β-boswellic acid, acetyl β-boswellic acid, acetyl 11-keto-β-boswellic acid, acetyl- α-boswellic acid, 3-oxo-tirucallic acid, and 3-hydroxy-tirucallic acid. The structures of the isolated compounds were deduced based on spectroscopic evidences. The lymphocyte transformation assay of the isolated compounds proved that the total extract retained more activity than that of any of the purified compounds.
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Siemoneit, Ulf, Lars Tausch, Daniel Poeckel, Michael Paul, Hinnak Northoff, Andreas Koeberle, Johann Jauch, and Oliver Werz. "Defined Structure-Activity Relationships of Boswellic Acids Determine Modulation of Ca2+ Mobilization and Aggregation of Human Platelets by Boswellia serrata Extracts." Planta Medica 83, no. 12/13 (April 12, 2017): 1020–27. http://dx.doi.org/10.1055/s-0043-107884.

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AbstractBoswellic acids constitute a group of unique pentacyclic triterpene acids from Boswellia serrata with multiple pharmacological activities that confer them anti-inflammatory and anti-tumoral properties. A subgroup of boswellic acids, characterized by an 11-keto group, elevates intracellular Ca2+ concentrations [Ca2+]i and causes moderate aggregation of human platelets. How different BAs and their mixtures in pharmacological preparations affect these parameters in activated platelets has not been addressed, so far. Here, we show that boswellic acids either antagonize or induce Ca2+ mobilization and platelet aggregation depending on defined structural determinants with inductive effects predominating for a B. serrata gum resin extract. 3-O-Acetyl-11-keto-β-boswellic acid potently suppressed Ca2+ mobilization (IC50 = 6 µM) and aggregation (IC50 = 1 µM) when platelets were activated by collagen or the thromboxane A2 receptor agonist U-46619, but not upon thrombin. In contrast, β-boswellic acid and 3-O-acetyl-β-boswellic acid, which lack the 11-keto moiety, were weak inhibitors of agonist-induced platelet responses, but instead they elicited elevation of [Ca2+]i and aggregation of platelets (≥ 3 µM). 11-Keto-β-boswellic acid, the structural intermediate between 3-O-acetyl-11-keto-β-boswellic acid and β-boswellic acid, was essentially inactive independent of the experimental conditions. Together, our study unravels the complex agonizing and antagonizing properties of boswellic acids on human platelets in pharmacologically relevant preparations of B. serrata gum extracts and prompts for careful evaluation of the safety of such extracts as herbal medicine in cardiovascular risk patients.
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Greve, Hippolyt L., Marcel Kaiser, Pascal Mäser, and Thomas J. Schmidt. "Boswellic Acids Show In Vitro Activity against Leishmania donovani." Molecules 26, no. 12 (June 15, 2021): 3651. http://dx.doi.org/10.3390/molecules26123651.

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In continuation of our search for leads from medicinal plants against protozoal pathogens, we detected antileishmanial activity in polar fractions of a dichloromethane extract from Boswellia serrata resin. 11-keto-β-boswellic acid (KBA) could be isolated from these fractions and was tested in vitro against Leishmania donovani axenic amastigotes along with five further boswellic acid derivatives. 3-O-acetyl-11-keto-β-boswellic acid (AKBA) showed the strongest activity with an IC50 value of 0.88 µM against axenic amastigotes but was inactive against intracellular amastigotes in murine macrophages
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Lu, Cheng Wei, Tzu Yu Lin, and Su Jane Wang. "11-Keto-β-Boswellic Acid Attenuates Glutamate Release and Kainic Acid-Induced Excitotoxicity in the Rat Hippocampus." Planta Medica 86, no. 06 (February 25, 2020): 434–41. http://dx.doi.org/10.1055/a-1107-9337.

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AbstractExcessive glutamate concentration induces neuronal death in acute brain injuries and chronic neurodegenerative diseases. Natural compounds from medicinal plants have attracted considerable attention for their use in the prevention and treatment of neurological disorders. 11-Keto-β-boswellic acid, a triterpenoid found in the medicinal plant Boswellia serrata, has neuroprotective potential. The present study investigated the effect of 11-keto-β-boswellic acid on glutamate release in vitro and kainic acid-induced glutamate excitotoxicity in vivo in the rat hippocampus. In rat hippocampal nerve terminals (synaptosomes), 11-keto-β-boswellic acid dose-dependently inhibited 4-aminopyridine-stimulated glutamate release. This effect was dependent on extracellular calcium, persisted in the presence of the glutamate transporter inhibitor DL-threo-β-benzyloxyaspartate, and was blocked by the vesicular transporter inhibitor bafilomycin A1. In addition, 11-keto-β-boswellic acid reduced the 4-aminopyridine-induced increase in intrasynaptosomal Ca2+ levels. The N- and P/Q-type channel blocker ω-conotoxin MVIIC and the protein kinase A inhibitor H89 significantly suppressed the 11-keto-β-boswellic acid-mediated inhibition of glutamate release, whereas the intracellular Ca2+-releasing inhibitors dantrolene, CGP37157, and xestospongin C, mitogen-activated protein kinase inhibitor PD98059, as well as protein kinase C inhibitor calphostin C had no effect. In a rat model of excitotoxicity induced by intraperitoneal kainic acid injection (15 mg/kg), intraperitoneal 11-keto-β-boswellic acid administration (10 or 50 mg/kg) 30 min before kainic acid injection considerably ameliorated kainic acid-induced glutamate concentration elevation and CA3 neuronal death. These data suggested that 11-keto-β-boswellic acid inhibits glutamate release from the rat hippocampal synaptosomes by suppressing N- and P/Q-type Ca2+ channels and protein kinase A activity, as well as exerts protective effects against kainic acid-induced excitotoxicity in vivo.
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Alyahya, AbdulRahman A. I., Mohammed Asad, Syed Mohammed Basheeruddin Asdaq, Yahya Mohzari, Ahmed Alrashed, Hamdan Najib Alajami, Awad Othman Aljohani, Abdullah Ali Al Mushtawi, AssilNajib Alajmi, and Hanan Nageeb Alajmi. "Haematotoxic effects of methanolic extract of Boswellia sacra oleo gum resin (frankinccense) in rats." Science Progress 104, no. 2 (April 2021): 003685042110151. http://dx.doi.org/10.1177/00368504211015102.

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In several parts of the world, Boswellia sacra Fluck. is one of the most commonly used herbs for the treatment of arthritis. Its usage should be validated in light of recent findings of haematotoxicity. This study was aimed to determine the effect of chronic administration of standardized methanolic extract of frankincense on blood cell count in experimental animals. Using high-performance liquid chromatography, the active constituents of B. sacra extract; boswellic acids were analyzed. The effect of three different doses of the extract (250, 500, and 1000 mg/kg) on different blood cells and associated parameters was investigated. The behavior, food, and water consumption of the rats were recorded. Boswellic acids were present in varying amounts with α-boswellic acid and β-boswellic acid present in more amounts compared to other boswellic acids in the extract. All three doses tested had no effect on the animals’ behavior, food consumption, or weight gain. The administration of a low (500 mg/kg) and high (1000 mg/kg) dose of the extract resulted in a non-dose dependent reduction in MCH ( p < 0.01 and p < 0.05, respectively), but no other blood parameters were significantly affected. The B. sacra extract produces hypochromic normocytic anemia in rats at higher doses of 500 and 1000 mg/kg and this effect was not dose-dependent.
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Soliman, Alaa M., Raniah R. Majeed, Hala F. Ali Himyari, Dhanalekshmi UM, and Shah A. Khan. "In vitro Cytotoxic, Antioxidant and Antimicrobial Activities of Alcoholic and Chloroform Extracts of Dhofari Frankincense." Dhaka University Journal of Pharmaceutical Sciences 19, no. 2 (December 10, 2020): 105–10. http://dx.doi.org/10.3329/dujps.v19i2.50624.

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Omani (Dhofari) frankincense is world famous for its high quality and fragrance. The oleo-gum resin obtained from the tree of Omani species i.e., Boswellia sacra (local name: luban) is widely used by the natives. The aim of the study was to determine the presence of phytochemicals in chloroform and ethanol extracts of B. sacra resin and to evaluate the in vitro cytotoxic, antimicrobial- and antioxidant-activities. The ethanol and chloroform extracts of Hojari luban were obtained in good yield. The extracts were subjected to phytochemical screenings, quantification of total phenolics (TP) and evaluation of in vitro biological activities viz. antioxidant, antibacterial and cytotoxic potential. The bioactivities of four boswellic acids, the major constituents of the oleo-gum resin, were also predicted with the help of PASS and CLC-pred software. Both the extracts showed similar level of TP (14.67 mg/g and 14.79 mg/g in terms of gallic acid equivalent) but polar fraction was noted to be more active against E. coli. A moderate antioxidant activity was shown by the resin extracts however their cytotoxic activity was observed to be quite remarkable at 1000 μg/l which could be attributed to their high boswellic acid content. Results of in silico PASS studies showed boswellic acids to possess an array of useful biological activities including chemopreventive activity. Further, CLC-pred software revealed that only keto boswellic acid is expected to exert antineoplastic activity against pancreatic carcinoma cell lines, however all the four major boswellic acids are likely to be active against non-tumor embryonic lung fibroblast (MRC5). The study confirmed that frankincense is rich in bioactive metabolites which are of significant economic and therapeutic importance. Dhaka Univ. J. Pharm. Sci. 19(2): 105-110, 2020 (December)
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Ghorpade, Ravi, Arvind Chopra, and Tukaram Nikam. "Influence of organic supplements on accumulation of β-boswellic acid, acetyl-β-boswellic acid, 11-keto-β-boswellic acid and acetyl-11-keto-β-boswellic acid in callus culture of Boswellia serrata Roxb." Acta Physiologiae Plantarum 34, no. 6 (June 6, 2012): 2275–83. http://dx.doi.org/10.1007/s11738-012-1028-5.

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Dissertations / Theses on the topic "Boswellic acid"

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Swarup, Ashish, and ash198@gmail com. "Application of Traditional Medicines on Textiles." RMIT University. Fashion and Textiles, 2007. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080521.114106.

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As science and technology has developed, the manner by which drugs can be delivered has grown. This research explores an alternative method for the delivery of therapeutic compounds to the body. The basis of the study involves the application of traditional medicines on textiles. Boswellia Serrata Extract (B.S.E.) is a common traditional medicine used for curing body pains. The most common form of B.S.E. based products are creams that are applied directly to the skin. Experiments show that these creams were not suitable as a basis for applying to textile materials because the creams contain highly volatile compounds, which on drying the treated textile, post application, cause almost total loss of the B.S.E. The approach used was the application on textiles of a 'commercial' topical medicine applied as a cream for, where B.S.E. is a major constituent. Cotton woven fabric was padded with this cream and tested for washing and rubbing fastness. The presence of highly volatile substances in the topical cream resulted in a negligible amount of the medicine on the dried treated fabric. Another approach was used for the application of B.S.E. onto the textile substrate. A commercially available B.S.E. powder was applied to woven fabric using a pad mangle. Tests were carried out to validate the
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Henkel, Arne [Verfasser], and Oliver [Akademischer Betreuer] Werz. "Novel Molecular Targets of Boswellic Acids and Characterization of Bioactive Ingredients of Frankincense / Arne Henkel ; Betreuer: Oliver Werz." Tübingen : Universitätsbibliothek Tübingen, 2011. http://d-nb.info/1162698950/34.

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Basar, Simla [Verfasser]. "Phytochemical investigations on Boswellia species : comparative studies on the essential oils, pyrolysates and boswellic acids of Boswellia carterii Birdw., Boswellia serrata Roxb., Boswellia frereana Birdw., Boswellia neglecta S. Moore and Boswellia rivae Engl. / by Simla Basar." 2005. http://d-nb.info/975255932/34.

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Tausch, Lars [Verfasser]. "Novel anti-inflammatory targets and mechanisms of boswellic acids and celecoxib / von Lars Tausch." 2008. http://d-nb.info/1001824369/34.

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Pöckel, Daniel [Verfasser]. "Pharmacological actions and targets of boswellic acids in human leukocytes and platelets / von Daniel Pöckel." 2006. http://d-nb.info/982417829/34.

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Siemoneit, Ulf [Verfasser]. "Anti-inflammatory actions of boswellic acids : identification and critical evaluation of molecular targets and signaling pathways = Entzündungshemmende Wirkungen von Boswelliasäuren / vorgelegt von Ulf Siemoneit." 2009. http://d-nb.info/996706674/34.

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Books on the topic "Boswellic acid"

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Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia. Elsevier, 2019. http://dx.doi.org/10.1016/c2016-0-04058-5.

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Book chapters on the topic "Boswellic acid"

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Park, Yong Seok, Joung H. Lee, Jyoti A. Harwalkar, Judy Bondar, Hasan Safayhi, and Mladen Golubic. "Acetyl-11-Keto-ß-Boswellic Acid (Akba) is Cytotoxic for Meningioma Cells and Inhibits Phosphorylation of the Extracellular-Signal Regulated Kinase 1 and 2." In Advances in Experimental Medicine and Biology, 387–93. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0193-0_60.

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Ammon, H. P. T. "Boswellic Acids and Their Role in Chronic Inflammatory Diseases." In Advances in Experimental Medicine and Biology, 291–327. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-41334-1_13.

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Satpathy, Raghunath. "Therapeutic Importance and Application of Boswellic Acid From the Plant Boswellia serrata." In Advanced Pharmacological Uses of Medicinal Plants and Natural Products, 302–15. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-2094-9.ch016.

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Traditionally, the gum resin produced from the Boswellia serrata plant has been used in as a therapeutical compound. The gum that contains a chemical known as boswellic acid, AKBA (3-O-acetyl-11 keto-β-boswellic acid), and widely in ayurvedic medicines. This is used to treat the disease like reduction in various inflammatory conditions of the skin, eye, as well as respiratory disorders such as asthma, bronchitis, and laryngitis. The boswellic acids were also found capable to inhibit both hemolysis and chemotaxis of leukocytes and were shown to work by inhibiting C3-convertase, a key enzyme of the classical complementary pathway. In addition to this, the compound shows beneficial effects in various pharmacological properties like immunomodulation activity, polyarthritis, activity against Hepatitis C-virus and other harmful microbes, Colitis and Crohn's disease, and so on. The boswellic acid is also used to treat patients with memory disorders. In this chapter, the chemical nature and isolation of boswellic acid and its therapeutic importance have been highlighted.
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Al-Harrasi, Ahmed, Hidayat Hussain, Rene Csuk, and Husain Y. Khan. "Biological Activities of Boswellic Acids." In Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia, 67–109. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-08-102441-6.00003-7.

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Al-Harrasi, Ahmed, Hidayat Hussain, Rene Csuk, and Husain Y. Khan. "Taxonomy of Boswellia Tree, Traditional Medicinal Uses of Frankincense and Historical Aspects of Boswellic Acids." In Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia, 1–7. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-08-102441-6.00001-3.

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"Boswellic Acids as Potential Cancer Therapeutics." In Cancer Preventive and Therapeutic Compounds: Gift From Mother Nature, edited by Manjeet Kumar, Arvind Kumar, Omkar P. Dhamale, and Bhahwal Ali Shah, 32–63. BENTHAM SCIENCE PUBLISHERS, 2017. http://dx.doi.org/10.2174/9781681084916117010006.

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Al-Harrasi, Ahmed, Hidayat Hussain, Rene Csuk, and Husain Y. Khan. "Chemistry of Boswellic Acids and Other Terpenoids." In Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia, 9–66. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-08-102441-6.00002-5.

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Al-Harrasi, Ahmed, Hidayat Hussain, Rene Csuk, and Husain Y. Khan. "Biological Activities of Boswellia Extract." In Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia, 111–25. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-08-102441-6.00004-9.

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Al-Harrasi, Ahmed, Hidayat Hussain, Rene Csuk, and Husain Y. Khan. "Frankincense in Modern Medicine." In Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia, 127–36. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-08-102441-6.00005-0.

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"Front-matter." In Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia, i—iii. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-08-102441-6.00006-2.

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Conference papers on the topic "Boswellic acid"

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Kaya, Ayşenur. "The Apoptotic Effect of the Acetyl-11-keto-beta-boswellic acid (AKBA) to Anaplastic Thyroid Cancer." In 15th International Congress of Histochemistry and Cytochemistry. Istanbul: LookUs Scientific, 2017. http://dx.doi.org/10.5505/2017ichc.pp-130.

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AlSalmani, Kamla KSA, Marcus S. Cooke, Ikram A. Burney, and Mark D. Evans. "Abstract A43: Evaluation of the cytotoxic effects of 3-O-acetyl-11-keto-β-boswellic acid in ovarian cancer cells." In Abstracts: AACR Special Conference on Advances in Ovarian Cancer Research: From Concept to Clinic; September 18-21, 2013; Miami, FL. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1078-0432.ovca13-a43.

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Toden, Shusuke, Yoshinaga Okugawa, Keun Hur, Thomas A. Jascur, Constanze Burhrmann, Durgha Nattamai, Esperanza Anguiano, Mehdi Shakibaei, C. Richard Boland, and Ajay Goel. "Abstract 4119: Novel evidence for chemopreventive effects of curcumin and boswellic acid through regulation of mir-27a and mir-34a in human colorectal cancer." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4119.

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Boren, Richard M., Charles F. Hammel, and Mark R. Bleckinger. "Multi-Pollution Removal System Using Oxides of Manganese." In ASME 2004 Power Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/power2004-52081.

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Pending legislation suggests there will be a need for increased removal of NOx, SO2, Hg (Mercury) and PM 2.5 from coal-fired power plants. Current commercial technologies only handle one of these pollutants so several different technologies must be combined to remove all of these pollutants. The Pahlman™ Process developed by Enviroscrub Technologies removes NOx, SO2 and Hg in one step. The Pahlman™ Process is a sorbent-based technology, which utilizes a proprietary Oxides of Manganese compound to remove SO2, NOx and Hg. The sorbent is spray-dried into the exhaust duct downstream of the current particulate control device. Spray drying is used to control the particle size (40 micron mean) and increases the surface area of the particle (∼300 m2 /gram). The sorbent is collected in a fabric filter baghouse, which serves two purposes: (1) it captures the entrained sorbent and (2) provides additional residence time for gas-solid contact between the sorbent and the target pollutants. The loaded sorbent is removed from the baghouse and routed to regeneration. Sorbent regeneration occurs in an aqueous solution under temperature and pressure while the solution is maintained in the proper pH and Eh ranges. The reacted manganese is oxidized back to its starting state and sulfate and nitrate byproduct compounds are produced. The insoluble oxides of manganese are then filtered out of the solution and returned to the spray-dryer for re-use. The soluble sulfate and nitrate compounds are separated and the nitrate by-products are sold as fertilizer. The sulfates are further processed and re-used in the regeneration process with excess sulfate by-products sold as fertilizer or used to produce sulfuric acid. Testing over the last three years has resulted in consistent SO2 removal of over 99% and NOx removal of greater than 95%. Testing performed in June 2003 at DTE Energy’s River Rouge Power Station Unit#3 in Detroit, Michigan showed removal rates of >99% for SO2, >98% for NOx and 97% for oxidized Mercury (Hg2+). Mercury testing was performed by the Energy and Environmental Research Center (EERC) and paid for by DTE Energy and the DOE. Testing performed in December 2003 through January 2004 at Minnesota Power’s Boswell Energy Center Unit#4 in Cohasset, Minnesota showed removal rates of >98% for SO2, >94% for NOx and 99.2% for elemental (Hg0) and 94% for total Mercury (HgT).
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