Dissertations / Theses on the topic 'Borel measure'

In this thesis we study descriptive-set-theoretic and measure-theoretic properties of Polish groups, with a thematic emphasis on the contrast between groups which are locally compact and those which are not. The work is divided into three major sections. In the first, working jointly with Robert Kallman, we resolve a conjecture of Gleason regarding the Polish topologization of abstract groups of homeomorphisms. We show that Gleason's conjecture is false, and its conclusion is only true when the hypotheses are considerably strengthened. Along the way we discover a new automatic continuity result for a class of functions which behave like but are distinct from functions of Baire class 1. In the second section we consider the descriptive complexity of those subsets of the permutation group S? which arise naturally from the classical Levy-Steinitz series rearrangement theorem. We show that for any conditionally convergent series of vectors in Euclidean space, the sets of permutations which make the series diverge, and diverge properly, are ?03-complete. In the last section we study the phenomenon of Haar null sets a la Christensen, and the closely related notion of openly Haar null sets. We identify and correct a minor error in the proof of Mycielski that a countable union of Haar null sets in a Polish group is Haar null. We show the openly Haar null ideal may be distinct from the Haar null ideal, which resolves an uncertainty of Solecki. We show that compact sets are always Haar null in S? and in any countable product of locally compact non-compact groups, which extends the domain of a result of Dougherty. We show that any countable product of locally compact non-compact groups decomposes into the disjoint union of a meager set and a Haar null set, which gives a partial positive answer to a question of Darji. We display a translation property in the homeomorphism group Homeo+[0,1] which is impossible in any non-trivial locally compact group. Other related results are peppered throughout.

Дисертацiя присвячена диференцiйовним мiрам на банахових многовидах з рiвномiрною структурою. Запропоновано метод побудови асоцiйованих мiр на поверхнях скiнченної корозмiрностi, вкладених у банахiв многовид з рiвномiрною структурою. Введено поняття асоцiйованої диференцiальної форми поверхнi та строго трансверсального до поверхнi набору векторних полiв. Доведено теорему “про узгодженiсть”, згiдно з якою поверхнева мiра задається однозначно асоцiйованою диференцiальною формою поверхнi. Показано транзитивнiсть запропонованої конструкцiї. На прикладi мiри Лебега в скiнченновимiрному просторi Rn та мiри об’єму на рiмановому многовидi з рiвномiрною структурою обґрунтовано її адекватнiсть. Отримано узагальнення низки результатiв з теорiї диференцiйовних мiр на лiнiйних просторах на випадок банахових многовидiв з рiвномiрною структурою. Доведено критерiй слабкої диференцiйовностi мiри уздовж обмеженого векторного поля, що узагальнює вiдомий результат В. I. Богачова.

Trembling aspen (Populus tremuloides Michx.) is one of the most common tree species in the boreal and temperate forests of North America. It grows on many different sites and associates with a variety of tree species. In BC, aspen is frequent throughout all submontane and montane continental forested zones. Relationships between environmental factors and forest productivity have been the subjects of many studies. Most of these studies, using various topographic, soil, physical and chemical properties as independent variables, had limited success in accounting for the variation in SI over a large geographic area. The objectives of this study were (1) to quantify relationships between aspen SI and environmental factors at two spatial scales, and (2) to develop predictive SI models from easily measurable environmental factors.

Abstract Maintaining connectivity in boreal streams by rehabilitation procedures is a challenging task that requires ecological understanding based on empirical research. In this thesis, I examined the effects of stream rehabilitation on densities and growth of brown trout (Salmo trutta L.), as well as on benthic biodiversity. As streams are known to be closely connected to their watersheds, I also examined the effects of watershed drainage activities on stream organisms. The results of this thesis have implications for enhancing salmonid populations, as well for maintaining stream biodiversity. First, regional climatic variability was shown to override local impacts of watershed management on stream biota. This highlights the importance of placing results from local studies in a regional context. Second, increased sedimentation that typically follows anthropogenic actions in the watershed did not only cause direct mortality on the early life stages of brown trout, but also forced them to emerge earlier from gravel and constrained their development. Thus, sedimentation may have far-reaching fitness consequences on juvenile salmonids. Third, while instream rehabilitation did enhance habitat diversity for salmonid fish, there were only marginal effects on juvenile fish and benthic biodiversity. Therefore, the factors limiting stream biota, and obscuring positive effects of rehabilitation, are to be found elsewhere. For this purpose, my thesis offers at least three potential, not mutually exclusive explanations: (i) land use changes have altered watersheds and this can be seen as decreased stream biodiversity that cannot be corrected through local-scale restoration efforts; (ii) a habitat-forming organism group, stream bryophytes, is dispersal limited, slowing down any positive responses to restoration by fish or invertebrates that depend strongly on bryophytes; and (iii) changes to stream habitat heterogeneity caused by channelization for timber floating were rather modest to start with, and therefore any effects of stream habitat rehabilitation on stream biota are likely to be subtle. Based on these findings, I suggest that future restoration efforts should be prioritized according to a comprehensive watershed assessment. Also, monitoring of projects should be more rigorous and preferably multidisciplinary, documenting the ecological as well as hydrological and socioeconomic outcomes of rehabilitation projects.

Bien que les stratégies de gestion du risque et de l'incertitude soient de plus en plus reconnues comme une dimension critique de l’aménagement des ressources naturelles, leur mise en œuvre reste encore à développer. Cependant la gravité du risque, les dommages potentiels qui y sont associés ainsi que sa probabilité d’occurrence demeurent souvent méconnus. Cette étude analyse différentes stratégies de gestion des risques utilisées dans la planification de l’aménagement forestier. Nous avons évalué des stratégies qui pouvaient protéger le niveau de récolte face aux risques de feu. Un modèle d'optimisation et de simulation a été conçu pour évaluer l'impact du risque de feu sur les calculs de possibilité forestière dans un contexte d’aménagement écosystémique de la zone boréale de la province de Québec au Canada. Nous avons comparé deux stratégies de mitigation des impacts. La stratégie dans laquelle les coûts d’une prime d'assurance sont pris en compte s’est révélée relativement meilleure que celle consistant à une mise en réserve de bois (chapitre I). Nous avons également évalué une stratégie menant à l’exclusion des peuplements les plus vulnérables au feu en raison de leur faible taux de croissance (chapitre II). Cette stratégie s’est également révélée meilleure que celle visant la mise en réserve de bois. Finalement, nous avons évalué le potentiel que présente la coupe partielle comme stratégie visant à réduire le temps d’exposition au risque. Combinée la mise en réserve de bois (fond de réserve), la coupe partielle s’avère un outil des plus utile (chapitre III). L’étude révèle qu’une stratégie ciblée telle que l’exclusion des peuplements vulnérables ou l’augmentation de la proportion des coupes partielles performe mieux qu’une stratégie non ciblée telle que le fond de réserve. Bien que nous ayons abordé différentes stratégies d’aménagement forestier dans cette thèse, des points importants restent encore à éclaircir, en particulier la tolérance au risque et le contexte dans lequel il se développe.
Bien que les stratégies de gestion du risque et de l'incertitude soient de plus en plus reconnues comme une dimension critique de l’aménagement des ressources naturelles, leur mise en œuvre reste encore à développer. Cependant la gravité du risque, les dommages potentiels qui y sont associés ainsi que sa probabilité d’occurrence demeurent souvent méconnus. Cette étude analyse différentes stratégies de gestion des risques utilisées dans la planification de l’aménagement forestier. Nous avons évalué des stratégies qui pouvaient protéger le niveau de récolte face aux risques de feu. Un modèle d'optimisation et de simulation a été conçu pour évaluer l'impact du risque de feu sur les calculs de possibilité forestière dans un contexte d’aménagement écosystémique de la zone boréale de la province de Québec au Canada. Nous avons comparé deux stratégies de mitigation des impacts. La stratégie dans laquelle les coûts d’une prime d'assurance sont pris en compte s’est révélée relativement meilleure que celle consistant à une mise en réserve de bois (chapitre I). Nous avons également évalué une stratégie menant à l’exclusion des peuplements les plus vulnérables au feu en raison de leur faible taux de croissance (chapitre II). Cette stratégie s’est également révélée meilleure que celle visant la mise en réserve de bois. Finalement, nous avons évalué le potentiel que présente la coupe partielle comme stratégie visant à réduire le temps d’exposition au risque. Combinée la mise en réserve de bois (fond de réserve), la coupe partielle s’avère un outil des plus utile (chapitre III). L’étude révèle qu’une stratégie ciblée telle que l’exclusion des peuplements vulnérables ou l’augmentation de la proportion des coupes partielles performe mieux qu’une stratégie non ciblée telle que le fond de réserve. Bien que nous ayons abordé différentes stratégies d’aménagement forestier dans cette thèse, des points importants restent encore à éclaircir, en particulier la tolérance au risque et le contexte dans lequel il se développe.
Although, management strategies dealing with risk and uncertainty have become a critical issue over the past several years, solutions are still to be developed. However, how can one judge the severity of risk when the potential damage and its probability are unknown? This study develops a framework for analyzing risk management strategies in forest management planning. We delineated how these management strategies could address the risk to protect timber harvest against disruptions. We tested optimization and simulation model to estimate the impact of risk associated with fire in timber supply calculations in an ecosystem context in boreal zone of the province of Quebec, Canada. Since paying, an insurance premium appeared to produce better results than partitioning buffer stock, (chapter I). The rating of wood volume available to harvest as a function of its vulnerability to fire can be used to reduce the impacts of fire on timber supply (chapter II). This idea was extended to test the adaptability of partial cutting coupled with buffer stock and accounting for the uncertainty induced by fire and projected climate scenarios (chapter III). As there are different levels of risk and different levels of tolerance to risk, the study results have shown that the process of risk evaluation itself needs to be accepted in its degree of uncertainties and its severity. As far as the insurance is concerned, it looks like a good strategy, but find an insurance company that is interested enough to believe there are enough potential customers to pay the premiums to make a profit could be required. The results also reveal that a targeted strategy such as excluding vulnerable stands from timber supply or adaptation of silvicultural treatment such as partial cutting may greatly interesting when facing risk scenario. Although, we covered different forest management strategies in this thesis, important issues still need to be considered in order to improve the knowledge associated with risk of fire; especially the context in which it develops.
Although, management strategies dealing with risk and uncertainty have become a critical issue over the past several years, solutions are still to be developed. However, how can one judge the severity of risk when the potential damage and its probability are unknown? This study develops a framework for analyzing risk management strategies in forest management planning. We delineated how these management strategies could address the risk to protect timber harvest against disruptions. We tested optimization and simulation model to estimate the impact of risk associated with fire in timber supply calculations in an ecosystem context in boreal zone of the province of Quebec, Canada. Since paying, an insurance premium appeared to produce better results than partitioning buffer stock, (chapter I). The rating of wood volume available to harvest as a function of its vulnerability to fire can be used to reduce the impacts of fire on timber supply (chapter II). This idea was extended to test the adaptability of partial cutting coupled with buffer stock and accounting for the uncertainty induced by fire and projected climate scenarios (chapter III). As there are different levels of risk and different levels of tolerance to risk, the study results have shown that the process of risk evaluation itself needs to be accepted in its degree of uncertainties and its severity. As far as the insurance is concerned, it looks like a good strategy, but find an insurance company that is interested enough to believe there are enough potential customers to pay the premiums to make a profit could be required. The results also reveal that a targeted strategy such as excluding vulnerable stands from timber supply or adaptation of silvicultural treatment such as partial cutting may greatly interesting when facing risk scenario. Although, we covered different forest management strategies in this thesis, important issues still need to be considered in order to improve the knowledge associated with risk of fire; especially the context in which it develops.

Cette thèse est constituée de trois parties. Dans la première partie, on s'intéresse au problème de trace au bord d'une solution positive de l'équation de Hamilton-Jacobi (E1) $-\Delta u+g(|\nabla u|)=0$ dans un domaine borné $\Omega$ de ${\mathbb R}^N$, satisfaisant (E2) $u = \mu$ sur $\partial \Omega$. Si $g(r) \geq r^q$ avec $q > 1$, on prouve que toute solution positive de (E1) admet une trace au bord considérée comme une mesure de Borel régulière, pas nécessairement localement bornée. Si $g(r) = r^q$ avec $1 < q < q_c = \frac{N+1}{N}$ , on montre l'existence d'une solution positive dont la trace au bord est une mesure de Borel régulière $\nu \not \equiv \infty$ et on caractérise les singularités frontières isolées de solutions positives. Si $g(r) = r^q$ avec $q_c \leq q < 2$, on établit une condition nécessaire de résolution en terme de capacité de Bessel $C_{\frac{2-q}{q},q'} . On étudie aussi des ensembles éliminables au bord pour des solutions modérées. La deuxième partie est consacrée à étudier la limite, lorsque $k \to \infty$, de solutions d'équation $\partial_t u - \Delta u + f(u) =0$ dans ${\mathbb R}^N \times (0;\infty)$ avec donnée initiale $k\delta_0$ où $0$ est la masse de Dirac concentrée à l'origine et f est une fonction positive, continue, croissante et satisfaisant $f(0) = f^{-1}(0) = 0$. On prouve, sous certaines hypothèses portant sur f, qu'il existe essentiellement trois types de comportement possible en fonction des valeurs finies ou infinies des intégrales $\int_1^\infty f^{-1}(s)ds$ et $\int_1^\infty F^{-1/2}(s)ds$, où $F(s)=\int_0^s f(r)dr$. Grâce à ces résultats, on donne une nouvelle construction de la trace initiale et quelques résultats d'unicité et de non-unicité de solutions dont la donnée initiale n'est pas bornée. Dans la troisième partie, on élargit le cadre de nos investigations et généralise les résultats obtenus dans la deuxième partie au cas où l'opérateur est non-linéaire. En particulier, on s'intéresse à des propriétés qualitatives de solutions positives de l'équation $ \partial_t u-\Delta_p u+f(u)=0$ où $p > 1, \Delta_p u = div(\abs{\nabla u}^{p-2}\nabla u)$ et $f$ est une fonction continue, croissante, positive et satisfaisant $f(0) = 0 = f^{-1}(0)$. Si $p > \frac{2N}{N+1}$, on fournit une condition suffisante portant sur f pour l'existence et l'unicité des solutions fondamentales de données initiales $k\delta_0$ et on étudie la limite, lorsque $k \to \infty$, qui dépend du fait que $f^{-1}$ et $F^{-1/p}$ soient intégrables à l'infini ou pas, où $F(s) =\int_0^s f(r)dr. On donne aussi de nouveaux résultats de non-unicité de solutions avec donnée initiale non bornée. Si $p \geq 2$, on prouve que toute solution positive admet une trace initiale dans la classe de mesures de Borel régulières positives. Finalement on applique les résultats ci-dessus au cas modèle $f(u)=u^\alpha \ln^\beta(u+1)$ avec $\alpha>0$ et $\beta>0$.

Objectifs : La maladie de Crohn (MC) et la colite ulcéreuse (CU) sont associées à un fardeau socio-économique important. Au Canada, les analyses de coûts-utilité (ACU) sont privilégiées afin d’assurer l’allocation optimale des ressources. La mesure d’utilité est essentielle pour réaliser une ACU. L’objectif de ce projet visait à identifier les mesures d’utilité et d’estimer l’impact de ces mesures sur le ratio coût-utilité incrémental (RCUI) des traitements indiqués pour la MC. Méthodes : Un arbre décisionnel a été développé pour mesurer l’impact des valeurs d’utilité du EQ-5D, de l’échelle visuelle analogue (VAS), de l’arbitrage temporel (TTO) et du pari standard (SG), sur le RCUI d’Infliximab (IFX) + Traitements standards (TS) (prednisone, mesalazine (MZ), azathioprine (AZA), 6-mercaptopurine (6-MP)) vs Placébo + TS. Le modèle a porté sur un horizon temporel d’un an, selon les perspectives du système de soins et sociétale. Les moyennes pondérées des mesures d’utilité ont été estimées à partir d’une revue systématique de la littérature. Des analyses de sensibilités déterministes et probabilistes ont également été effectuées. Résultats : L’ensemble des RCUIs, variaient entre 67 068 $/QALY (TTO) et 268 385 $/QALY (EQ-5D). À un seuil de propension à payer de 50 000 $/QALY, la probabilité qu’IFX + TS soit coût efficace était nulle pour l’ensemble des analyses, à l’exception de celle du TTO (4,0%). Conclusion : La variabilité des mesures d’utilité a un impact considérable sur les RCUIs et nécessite une attention particulière de la part des preneurs de décisions, plus précisément au niveau des analyses de sensibilité.
Objectives: Crohn’s disease (CD) and ulcerative colitis are both associated with a high socioeconomic burden. In Canada, cost-utility analyses (CUA) are privileged in order to allocate healthcare spending efficiently. Since utility measures are essential for CUA, the objective of this study was to assess the impact utility values on the incremental cost-utility ratio (ICUR) of CD treatments. Methods: A decision-tree model was developed to assess the impact of utility values derived from the EQ-5D, the visual analogue scale (VAS), the time trade off (TTO) and the standard gamble (SG), on the resulted ICUR of Infliximab (IFX) + Standard of Care (SoC) (prednisone, mesalazine (MZ), azathioprine (AZA), 6-mercaptopurine (6-MP)) versus Placebo (Pbo) + SoC. The model was conducted over a one-year time horizon from the Canadian healthcare and societal perspectives. The weighted averages of utility values were estimated based on a systematic literature evaluation. Both deterministic and probabilistic sensitivity analyses were also conducted. Results: The ICURs ranged from $67,068/QALY (TTO) to $268,385/QALY (EQ-5D). At a $50,000/QALY threshold, the probability of IFX + SoC of being cost-effective was of 0% in most analyses except for the TTO method (4.0%). Conclusion: The variability of utility measures has a considerable impact on the ICURs and requires a special attention from decision-makers, in regards of sensitivity analyses.

Tese de Doutoramento em Psicologia, na especialidade de Psicologia Clínica, apresentada à Faculdade de Psicologia e de Ciências da Educação
Chronic illness is an increasingly predominant problem among the world population which vastly impacts on physical and mental health, quality of life and social functioning. Although chronic illnesses merit a long-term and complex response which would be ideally delivered by a multidisciplinary team of health professionals, most of the current healthcare for chronic illnesses still focus on acute episodes of illness. The third wave of cognitive and behavioural approaches on psychological problems, in particular mindfulness, Acceptance and Commitment Therapy, and evolutionary and compassion-based approaches have presented promising perspectives on behavioural medicine. Nevertheless, the efficacy of third wave interventions in improving well-being and mental health in chronic illness, although promising, is not yet clear. This doctoral dissertation aimed to contribute to a greater understanding of the psychological mechanisms that influence the vulnerability and persistence of psychological, social, and physical impairment in chronic illness. The role of verbal and emotion regulation processes aligned with third wave approaches’ conceptualizations of psychological problems in the comprehension of psychosocial and physical problems in chronic illness was thus explored in this dissertation. With this information, this thesis also aimed to develop, apply and test the efficacy of a new integrative acceptance, mindfulness, and compassion-based intervention for cancer. Methods: This dissertation includes 18 empirical studies with cross-sectional and longitudinal designs, including the development and test of efficacy of the MIND programme for cancer patients. The majority of these studies were conducted in samples of inflammatory bowel disease patients and breast cancer patients. Some studies also included individuals from the general population, as well as mixed samples of chronic patients. Generally, participants were recruited via internet or from hospital outpatient units. Data was collected through self-report measures and, in some specific studies, from medical records. Results: Overall, the studies revealed that: i) The Engaged Living Scale and its new shorter version (ELS-9), and the Committed Action Questionnaire are valid measures of engaged living and committed action for the Portuguese population. ii) The new chronic illness-specific measures – the Chronic Illness-related Shame Scale (CISS) and the Cognitive Fusion Questionnaire - Chronic Illness (CFQ-CI) – are robust and valid instruments that enable the assessment of chronic illness-related shame and chronic illness-related cognitive fusion, respectively. iii) The studied verbal and emotion regulation processes (cognitive fusion, experiential avoidance, self-criticism, fear of compassion from others, and lack of committed action) seem to be more important to the comprehension of psychosocial problems in chronic illness than physical symptomatology and contextual variables, and seem to mediate the effects of these variables, as well as the effects of chronic illness shame and body image dissatisfaction, on psychological, social, and physical health outcomes. Cognitive fusion and experiential avoidance in particular were identified as fundamental causal processes in the determination of the level of psychological health and perceived physical health in chronic patients. iv) The integration of acceptance, mindfulness, and compassion-based approaches in chronic illness seems to be feasible. The MIND programme for cancer patients presented a seemingly increased efficacy on the improvement of psychological health in relation to other mindfulness-based interventions in the context of breast cancer. Preliminary results suggested that the programme is a feasible, useful, accessible and cost-effective complement to the treatment of breast cancer. Conclusions: This dissertation clarifies the role of verbal and emotion regulation processes in chronic illness, presenting particularly innovative data in inflammatory bowel disease. The findings give support to the pertinence of acceptance, mindfulness, and compassion-based approaches, as well as their complementary integration, in behavioural medicine. The findings were integrated in a new transdiagnostic model for the comprehension of psychosocial and physical impairment in chronic illness. This dissertation provides new opportunities for future research, especially regarding the application of the MIND programme in other chronic illness populations.
A doença crónica é um problema cada vez mais predominante entre a população mundial que impacta significativamente na saúde física e mental, qualidade de vida e funcionamento social dos doentes. Embora as doenças crónicas mereçam uma resposta complexa que idealmente incluiria uma equipa multidisciplinar de profissionais de saúde, a maioria dos cuidados de saúde dos doentes crónicos ainda se foca em episódios agudos de doença. As abordagens aos problemas psicológicos oferecidas pelas terapias cognitivocomportamentais de terceira geração, em particular a Terapia de Aceitação e Compromisso e as terapias baseadas no mindfulness e compaixão, têm apresentado perspetivas promissoras no contexto da medicina comportamental. No entanto, a eficácia de intervenções de terceira geração na melhoria de indicadores de bem-estar e saúde mental na doença crónica, embora prometedora, não é ainda clara. Esta dissertação de doutoramento pretende contribuir para uma melhor compreensão dos mecanismos psicológicos que influenciam a vulnerabilidade e manutenção de problemas psicológicos, sociais e físicos na doença crónica. Assim, esta dissertação pretendeu explorar o papel de processos verbais e de regulação emocional, alinhados com as conceptualizações dos modelos de terceira geração, na compreensão de problemas psicossociais e físicos no contexto da doença crónica. Com esta informação, este trabalho procurou também desenvolver, aplicar e testar a eficácia de uma nova intervenção integradora, baseada em aceitação, mindfulness, e compaixão, desenhada para doentes oncológicos. Métodos: Esta dissertação inclui 18 estudos empíricos com desenhos transversais e longitudinais, incluindo o desenvolvimento e teste de eficácia do programa MIND para doentes oncológicos. A maioria destes estudos foram conduzidos em amostras de doentes com doença inflamatória intestinal e doentes com cancro da mama. Alguns estudos também incluíram indivíduos da população geral, assim como amostras mistas de doentes crónicos. A maioria dos participantes foram recrutados através da internet ou através de serviços hospitalares de consulta externa. Os dados foram recolhidos através de medidas de autorresposta e, em alguns estudos específicos, através de registos médicos. Resultados: De um modo geral, os estudos revelaram que: i) A Engaged Living Scale e a sua nova versão mais curta (ELS-9), e o Committed Action Questionnaire são medidas válidas de vida comprometida e de ação comprometida com valores para a população Portuguesa. ii) As medidas específicas para a doença crónica desenvolvias no âmbito deste trabalho – a Chronic Illness-related Shame Scale (CISS) e o Cognitive Fusion Questionnaire - Chronic Illness (CFQ-CI) – são instrumentos válidos e robustos que permitem, respetivamente, a avaliação de vergonha e fusão cognitiva especificamente relacionados com doença crónica. iii) Os processos verbais e de regulação emocional estudados (fusão cognitiva, evitamento experiencial, autocriticismo, medo da compaixão dos outros, e falta de compromisso com ação valorizada) parecem ter um papel mais importante na compreensão dos problemas psicológicos na doença crónica, do que a sintomatologia física e variáveis contextuais, e parecem mediar os efeitos destas variáveis, assim como os efeitos da vergonha associada à doença crónica e insatisfação com a imagem corporal, em indicadores de saúde psicológica, social e física. A fusão cognitiva e o evitamento experiencial foram, em particular, identificados como processos causais fundamentais na determinação do nível de saúde psicológica e saúde física percebida em doentes crónicos. iv) A integração de abordagens baseadas em aceitação, mindfulness, e compaixão na doença crónica parece ser viável. O programa MIND para doentes oncológicos parece ter apresentado uma eficácia acrescida na melhoria da saúde psicológica, relativamente a outras intervenções baseadas em mindfulness no contexto do cancro da mama. Resultados preliminares sugerem que programa é um complemento útil, acessível e vantajoso para o tratamento do cancro da mama. Conclusões: Esta dissertação clarifica o papel de processos verbais e de regulação emocional na doença crónica, apresentando dados particularmente inovadores na doença inflamatória intestinal. Os resultados oferecem suporte à pertinência das abordagens baseadas na aceitação, mindfulness e compaixão, assim como da sua integração complementar, na medicina comportamental. Os dados obtidos foram integrados num novo modelo transdiagnóstico para a compreensão das dificuldades físicas e psicológicas na doença crónica. Esta dissertação proporciona novas oportunidades a investigações futuras, em particular em relação à aplicação do programa MIND em outras populações de doentes crónicos.