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1

Medicine, Conference on Skeletal Biology and. Skeletal biology and medicine. Boston, Mass: Published by Blackwell Pub. on behalf of the New York Academy of Sciences, 2007.

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2

NATO Advanced Study Institute on Advances in Bone Regulatory Factors: Morphology, Biochemistry, Physiology, and Pharmacology (1989 Erice, Italy). Bone regulatory factors: Morphology, biochemistry, physiology, and pharmacology. New York: Plenum Press, 1990.

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3

Jacques, Arlet, and Mazières B, eds. Bone circulation and bone necrosis: Proceedings of the IVth International Symposium on Bone Circulation, Toulouse (France), 17th-19th September 1987. Berlin: Springer-Verlag, 1990.

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4

Mone, Zaidi, New York Academy of Sciences, and Mount Sinai School of Medicine, eds. Skeletal biology and medicine. Boston, Mass: Blackwell Pub., on behalf of the New York Academy of Sciences, 2007.

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5

Conference on Skeletal Biology and Medicine (4th 2011 New York, N.Y.). Skeletal biology and medicine II: Bone and cartilage homeostasis and bone disease. Edited by Zaidi Mone. Boston, Mass: Published by Blackwell Pub. on behalf of the New York Academy of Sciences, 2011.

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6

Behari, Jitendra. Biophysical bone behavior. Singapore: John Wiley, 2009.

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7

Mone, Zaidi, and New York Academy of Sciences, eds. Skeletal biology and medicine. Boston, Mass: Published by Blackwell Pub. on behalf of the New York Academy of Sciences, 2010.

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8

NATO Advanced Study Institute on Advances in Bone Regulatory Factors: Morphology, Biochemistry, Physiology, and Pharmacology (1989 Erice, Italy). Bone regulatory factors: Morphology, biochemistry, physiology, and pharmacology. New York: Plenum Press, 1990.

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9

Linda-Joy, Lee, and Vleeming Andry, eds. The pelvic girdle: An integration of clinical expertise and research. 4th ed. Edinburgh: Elsevier/Churchill Livingstone, 2011.

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10

Lundon, Katie. Orthopedic rehabilitation science: Principles for clinical management of nonmineralized connective tissue. Amsterdam: Butterworth-Heinemann, 2003.

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11

Rosen, Vicki. The cellular and molecular basis of bone formation and repair. New York: Springer, 1995.

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12

1957-, Thies Robert Scott, ed. The cellular and molecular basis of bone formation and repair. Austin: R.G. Landes, 1995.

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13

The pelvic girdle: An approach to the examination and treatment of the lumbo-pelvic-hip region. Edinburgh: C. Livingstone, 1989.

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14

Lee, Diane. The pelvic girdle: An approach to the examination and treatment of the lumbo-pelvic-hip region. 2nd ed. Edinburgh: Churchill Livingstone, 1999.

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15

The pelvic girdle: An approach to the examination and treatment of the lumbo-pelvic-hip region. 3rd ed. Edinburgh: Churchill Livingstone, 2004.

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16

1917-, Bonfiglio Michael, and Campbell Crawford J, eds. Orthopedic pathophysiology in diagnosis and treatment. New York: Churchill Livingstone, 1990.

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17

Foucar, Kathryn. Bone marrow pathology. Chicago: ASCP Press, 1995.

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18

Foucar, Kathryn. Bone marrow pathology. 2nd ed. Chicago: ASCP Press, 2001.

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19

s, Arne Aara. Postural load and the development of musculo-skeletal illness. Oslo: Distributed by Almquist [sic] & Wiksell, 1987.

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20

Enneking, William F. Clinical musculoskeletal pathology. 3rd ed. Gainesville: University of Florida Press/J. Hillis Miller Health Science Center, 1990.

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21

B, Renner Jordan, ed. Diagnostic musculoskeletal surgical pathology: Clinicoradiologic and cytologic correlations. Philadelphia: W.B. Saunders, 2004.

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22

Henry J., M.D. Mankin. Pathophysiology or Orthopaedic Diseases (Great Educators). American Academy of Orthopaedic Surgeons, 2006.

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23

Khurana, Jasvir S. Bone Pathology. Humana, 2016.

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24

Bone Pathology. 2nd ed. Humana Press, 2008.

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25

Hammett-Stabler, Catherine A. Osteoporosis: From Pathophysiology to Treatment: Special Topics in Diagnostic Testing. American Association for Clinical Chemistry, 2004.

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26

Mekhanika biologicheskikh sistem pri patologicheskikh sostoi͡a︡nii͡a︡kh. Riga: "Zinatne", 1988.

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27

(Editor), Allan L. Goldstein, and Enrico Garaci (Editor), eds. Thymosins in Health and Disease: First International Conference (Annals of the New York Academy of Sciences). Wiley-Blackwell, 2007.

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28

1948-, Regling Günter, ed. Wolff's law and connective tissue regulation: Modern interdisciplinary comments on Wolff's law of connective tissue regulation and rational understanding of common clinical problems. Berlin: W. de Gruyter, 1992.

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29

Hukkanen, Mika V. J., 1962-, Polak Julia M, Hughes Sean, and Royal Postgraduate Medical School, eds. Nitric oxide in bone and joint disease. Cambridge, UK: Cambridge University Press, 1998.

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30

Bone Regulatory Factors: Morphology, Biochemistry, Physiology, and Pharmacology (Nato Science Series: A:). Springer, 1990.

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31

Takahashi, H. E. Mechanical Loading Of Bones And Joints. Edited by H. E. Takahashi. Springer, 1999.

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32

M, Lichtman David, and Alexander A. H, eds. The wrist and its disorders. 2nd ed. Philadelphia: Saunders, 1997.

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33

A, Schoutens, and NATO Advanced Research Workshop on Bone and Bone Marrow Circulation in Normal and Pathological Conditions (1992 : Brussels, Belgium), eds. Bone circulation and vascularization in normal and pathological conditions. New York: Plenum Press, 1993.

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34

Skeletal Biology and Medicine, Part A: Aspects of Bone Morphogenesis and Remodeling (Annals of the New York Academy of Sciences). Wiley-Blackwell, 2008.

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35

Orthopedic Rehabilitation Science: Principles for Clinical Management of Non-Mineralized Connective Tissue. Butterworth-Heinemann, 2002.

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36

Lundon, Katie. Orthopedic Rehabilitation Science: Principles for Clinical Management of Bone. Butterworth-Heinemann, 2000.

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37

Skeletal Biology And Medicine. Wiley-Blackwell, 2011.

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38

I, Tovey F., and Stamp T. C. B, eds. The measurement of metabolic bone disease. New York: Parthenon Pub. Group, 1995.

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39

R, Turner-Smith Alan, and Oxford Orthopaedic Engineering Centre, eds. Micromovement in orthopaedics. Oxford: Claredon Press, 1993.

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40

Theis, R. Scott, and Vicki Rosen. Cellular & Molec Basis Bone Format (Molecular Biology Intelligence Unit). Springer, 1996.

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41

Bone metastasis: Mechanisms and pathophysiology. Austin: R.G. Landes, 1996.

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42

Goldring, Steven R. Pathophysiology of periarticular bone changes in osteoarthritis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0005.

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Under physiological conditions, the subchondral bone of diarthrodial joints such as the hip, knee, and phalanges forms an integrated biocomposite with the overlying calcified and hyaline articular cartilage that is optimally organized to transfer mechanical load. During the evolution of the osteoarthritic process both the periarticular bone and cartilage undergo marked changes in their structural and functional properties in response to adverse biomechanical and biological signals. These changes are mediated by bone cells that modify the architecture and properties of the bone through active cellular processes of modelling and remodelling. These same biomechanical and biological factors also affect chondrocytes in the cartilage matrix altering the composition and structure of the cartilage and further disrupting the homeostatic relationship between the cartilage and bone. This chapter reviews the structural alterations and cellular mechanisms involved in the pathogenesis of osteoarthritis bone pathology and discusses potential approaches for targeting bone remodelling to attenuate the progression of the osteoarthritic process.
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43

Vleeming, Andry, Vert Mooney, Chris J. Snijders, Rob Stoeckart, and Thomas A. Dorman. Movement, Stability and Low Back Pain: The Essential Role of the Pelvis. Churchill Livingstone, 1997.

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44

Andry, Vleeming, ed. Movement, stability, and low back pain: The essential role of the pelvis. New York: Churchill Livingstone, 1997.

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45

(Editor), F. William Orr, and Gurmit Singh (Editor), eds. Bone Metastasis: Mechanisms and Pathophysiology (Medical Intelligence Unit). R. G. Landes, 1996.

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46

Gurmit, Singh, and Orr F. William, eds. Bone metastasis and molecular mechanisms: Pathophysiology. Dordrecht: Kluwer Academic, 2004.

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47

Orr, William, and Gurmit Singh. Bone Metastasis and Molecular Mechanisms: Pathophysiology. Springer-Verlag New York Inc., 2004.

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48

Singh, Gurmit. Bone Metastasis and Molecular Mechanisms: Pathophysiology. Springer, 2010.

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49

-B, Abou-Samra A., Mundy Gregory R, and Martin T. John, eds. Physiology and pharmacology of bone. Berlin: Springer-Verlag, 1993.

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50

Martin, T. John, and Gregory R. Mundy. Physiology and Pharmacology of Bone. Brand: Springer, 2011.

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