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Journal articles on the topic 'Bone void filler'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Anonymous. "Bone Void Filler." Orthopedics 25, no. 4 (2002): 440. http://dx.doi.org/10.3928/0147-7447-20020401-24.

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Dvorzhinskiy, Aleksey, Giorgio Perino, Robert Chojnowski, Marjolein C. H. van der Meulen, Mathias P. G. Bostrom, and Xu Yang. "Ceramic composite with gentamicin decreases persistent infection and increases bone formation in a rat model of debrided osteomyelitis." Journal of Bone and Joint Infection 6, no. 7 (2021): 283–93. http://dx.doi.org/10.5194/jbji-6-283-2021.

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Abstract. Introduction: Current methods of managing osteomyelitic voids after debridement are inadequate and result in significant morbidity to patients. Synthetic ceramic void fillers are appropriate for non-infected bone defects but serve as a nidus of re-infection in osteomyelitis after debridement. CERAMENT G (CG) is an injectable ceramic bone void filler which contains gentamicin and is currently being evaluated for use in osteomyelitic environments after debridement due to its theoretical ability to serve as a scaffold for healing while eliminating residual bacteria after debridement thr

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3

Blaha, J. David. "Calcium Sulfate Bone-Void Filler." Orthopedics 21, no. 9 (1998): 1017–19. http://dx.doi.org/10.3928/0147-7447-19980901-31.

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4

Sinha, R., PS Menon, and A. Chakranarayan. "Vitoss Synthetic Cancellous Bone (Void Filler)." Medical Journal Armed Forces India 65, no. 2 (2009): 173. http://dx.doi.org/10.1016/s0377-1237(09)80136-6.

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5

Schendel, Stephen A., and John Peauroi. "Magnesium-Based Bone Cement and Bone Void Filler." Journal of Craniofacial Surgery 20, no. 2 (2009): 461–64. http://dx.doi.org/10.1097/scs.0b013e31819b9819.

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6

Karr, Jeffrey C., Joseph Lauretta, and Georgia Keriazes. "In Vitro Antimicrobial Activity of Calcium Sulfate and Hydroxyapatite (Cerament Bone Void Filler) Discs Using Heat-Sensitive and Non–Heat-sensitive Antibiotics Against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa." Journal of the American Podiatric Medical Association 101, no. 2 (2011): 146–52. http://dx.doi.org/10.7547/1010146.

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Background: Several absorbable and nonabsorbable antibiotic carrier systems are available in the adjunctive surgical management of osteomyelitis of the foot, ankle, and lower leg. These carrier systems have significant limitations regarding which antibiotics can be successfully incorporated into the carrier vehicle. The calcium sulfate and hydroxyapatite Cerament Bone Void Filler is a biocompatible, absorbable ceramic bone void filler that can successfully deliver multiple heat-stable and heat-unstable antibiotics that have not been generally used before with antibiotic beads in treating muscu

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7

Pilliar, Robert M., Rita A. Kandel, Marc D. Grynpas, et al. "Calcium polyphosphate particulates for bone void filler applications." Journal of Biomedical Materials Research Part B: Applied Biomaterials 105, no. 4 (2016): 874–84. http://dx.doi.org/10.1002/jbm.b.33623.

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Punyanitya, Sittiporn, Rungsarit Koonawoot, Warangkul Punyanitya, and Phanlob Chankachang. "A Clinical Trial for Bone Void Filler Made from Derived Hydroxyapatite from Cockle Shell Mixed with Rice Starch." Key Engineering Materials 779 (September 2018): 50–53. http://dx.doi.org/10.4028/www.scientific.net/kem.779.50.

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In this study, we have demonstrated that bone void filler made from hydroxyapatite (HAP) which derived from cockle shell. This sample mixed with rice starch and can be used to augment new bone growth in the empty space defects of damaged hard tissue, such as bone, spine and skull. The chemical compositions of HAP get along with standard specification for composition of ceramic HAP for surgical implants (ASTM International: F1185-88). The starch content was in the safety range of classical cell culture formulation. 60 patients were treated with this bone void filler show successfully healing an

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Karr, Jeffrey C. "An Overview of the Percutaneous Antibiotic Delivery Technique for Osteomyelitis Treatment and a Case Study of Calcaneal Osteomyelitis." Journal of the American Podiatric Medical Association 107, no. 6 (2017): 511–15. http://dx.doi.org/10.7547/13-047.

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Background:A percutaneous antibiotic delivery technique (PAD-T) used for the adjunctive management of osteomyelitis is presented.Methods:This surgical technique incorporates a calcium sulfate and hydroxyapatite (calcium phosphate) bone void filler acting as a carrier vehicle with either an antibiotic or an antifungal medicine, delivering this combination directly into the area of osteomyelitis.Results:The benefit of the PAD-T is reviewed with a case presentation of a successfully treated calcaneal osteomyelitis.Conclusions:No previously reported PAD-T using a simple bone cortex incision in the

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10

Axén, Niklas, Tobias Persson, Kajsa Björklund, Hakan Engqvist, and Leif Hermansson. "An Injectable Bone Void Filler Cement Based on Ca-Aluminate." Key Engineering Materials 254-256 (December 2003): 265–68. http://dx.doi.org/10.4028/www.scientific.net/kem.254-256.265.

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11

Harris, Michael, Hamza Ahmed, Leslie Pace, Jon Minter, Michael Neel, and Jessica Jennings. "Evaluation of Antibiotic-Releasing Triphasic Bone Void Filler In-Vitro." Journal of Functional Biomaterials 9, no. 4 (2018): 55. http://dx.doi.org/10.3390/jfb9040055.

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Bone void fillers (BVFs) containing calcium sulfate, tricalcium phosphate (TCP), and hydroxyapatite can be loaded with antibiotics for infection treatment or prevention under surgeon-directed use. The aim of this study was to characterize the handling and elution properties of a triphasic BVF loaded with common antibiotics. BVF was mixed with vancomycin and/or tobramycin to form pellets, and the set time was recorded. A partial refreshment elution study was conducted with time points at 4, 8, and 24 h, as well as 2, 7, 14, 28, and 42 days. Effects on dissolution were evaluated in a 14-day diss

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12

Brooks, Amanda E., Benjamin D. Brooks, Sherry N. Davidoff, Paul C. Hogrebe, Mark A. Fisher, and David W. Grainger. "Polymer-controlled release of tobramycin from bone graft void filler." Drug Delivery and Translational Research 3, no. 6 (2013): 518–30. http://dx.doi.org/10.1007/s13346-013-0155-x.

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13

Karr, Jeffrey C. "Lower-Extremity Osteomyelitis Treatment Using Calcium Sulfate/Hydroxyapatite Bone Void Filler with Antibiotics." Journal of the American Podiatric Medical Association 108, no. 3 (2018): 210–14. http://dx.doi.org/10.7547/16-096.

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Background: Over a 74-month period (∼6 years), 143 lower-extremity osteomyelitis locations in 125 patients were treated with a calcium sulfate/hydroxyapatite liquid bone void filler with antibiotic(s). Methods: The osteomyelitis locations were treated with a percutaneous antibiotic delivery technique delivering intraosseous antibiotic followed by either oral or intravenous antibiotics for 4 weeks. Results: There was no recurrence of osteomyelitis in 96.15% of the treatable patients. Outcomes classified by the Cierny-Mader clinical classification are discussed as well. Conclusions: A bone void

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14

Kotrych, Daniel, Szymon Korecki, Paweł Ziętek, et al. "Preliminary results of Highly Injectable Bi-Phasic Bone Substitute (CERAMENT) in the treatment of benign bone tumors and tumor-like lesions." Open Medicine 13, no. 1 (2018): 487–92. http://dx.doi.org/10.1515/med-2018-0072.

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AbstractBackground: CERAMENT™|BONE VOID FILLER is an injectable and moldable ceramic bone substitute material intended for bone voids. The material consists of hydroxyapatite and calcium sulfate hemihydrate. The aim of this study is to present the first long-term results following open curettage of benign bone tumors and tumor-like lesions and void filling with this novel injectable and synthetic bone graft. Methods: Thirty three patients were enrolled into the study between June 2013 and October 2014 .Totally, we treated 24 women and 9 men with a median age of 47 years (range: 22-74). All pat

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Punyanitya, Sittiporn, Warangkul Punyanitya, Sakdiphon Thiansem, and Rungsarit Koonawoot. "Fabrication and Characterization of Novel Bone Void Filler Made from Hydroxyapatite-Rice Starch Composite." Key Engineering Materials 779 (September 2018): 45–49. http://dx.doi.org/10.4028/www.scientific.net/kem.779.45.

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The aim of this study is fabricated bone void filler (BVF) made from hydroxyapatite (HA)-rice starch (RS) composite. We provided HA derived from cockle shells and RS derived from Thai rice starch. BVF was prepared by adding the pore former method to mimic the pore structure of bones. The samples were heated at 1250°C for 3 hours. Then, the composites were prepared by dipping and coating surface of the samples with RS gel. Scanning electron microscopy (SEM) and X-ray diffraction (XRD) confirmed that bovine bone and BVF are made of HA phase. Film of RS gel coated on surface of samples indicated

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Karr, Jeffrey C. "Management in the Wound-care Center Outpatient Setting of a Diabetic Patient with Forefoot Osteomyelitis Using Cerament Bone Void Filler Impregnated with Vancomycin." Journal of the American Podiatric Medical Association 101, no. 3 (2011): 259–64. http://dx.doi.org/10.7547/1010259.

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Several nonbiodegradable and biodegradable antibiotic cement delivery systems are available for the delivery of antibiotics for adjunctive therapy in the management of osteomyelitis. A major nonbiodegradable delivery system is polymethylmethacrylate beads. Antibiotics that can be incorporated into this delivery system are limited to the heat-stable antibiotics vancomycin and aminoglycosides, tobramycin being the most popular. Calcium sulfate and hydroxyapatite (Cerament Bone Void Filler) is a unique biocompatible and biodegradable ceramic bone void filler that can successfully deliver heat-sta

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17

Pietrzak, William S., and Robert Ronk. "Calcium Sulfate Bone Void Filler: A Review and a Look Ahead." Journal Of Craniofacial Surgery 11, no. 4 (2000): 327–33. http://dx.doi.org/10.1097/00001665-200011040-00009.

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18

Lewis, Christine S., Jordan Katz, Maribel I. Baker, Peter R. Supronowicz, Elise Gill, and Ronald R. Cobb. "Local Antibiotic Delivery with Bovine Cancellous Chips." Journal of Biomaterials Applications 26, no. 4 (2010): 491–506. http://dx.doi.org/10.1177/0885328210375729.

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Infected bone defects and osteomyelitis are encountered frequently in trauma cases. Currently, the standard of care for osteomyelitis cases is prolonged systemic antibiotic therapy and implantation of antibiotic carrier beads. However, this method requires a secondary surgery to remove the beads after the infection has cleared. In the present study a common bone void filler was investigated for its ability to be infused with an antibiotic. This study demonstrates that the xenograft material tested can be loaded with gentamicin and release clinically relevant levels of the drug for at least 14

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19

Mahan, KT, and MJ Carey. "Hydroxyapatite as a bone substitute." Journal of the American Podiatric Medical Association 89, no. 8 (1999): 392–97. http://dx.doi.org/10.7547/87507315-89-8-392.

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A bone substitute eliminates the need for autogenous and allogeneic bone grafting, along with the complications unique to each. Coralline hydroxyapatite is a synthetic bone void filler manufactured from marine coral, which has a natural trabecular structure similar to that of cancellous bone. While initial studies have been promising, the use of coralline hydroxyapatite may be limited in the foot and ankle owing to its inherent mechanical weakness and lack of biodegradation. In this retrospective study, 20 patients who received coralline hydroxyapatite implants were reviewed to determine assoc

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20

Eriwati, Yosi Kusuma, Difa Putri Utami, Dede Arsista, Sunarso Sunarso, and Siti Triaminingsih. "Characterization of Granular Calcium Sulfate Dihydrate-Gelatin Composite for Bone Void Filler." Key Engineering Materials 829 (December 2019): 69–74. http://dx.doi.org/10.4028/www.scientific.net/kem.829.69.

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Calcium sulfate dihydrate (CSD) cement has been used as bone filler for decades. It is also used as antibiotics carrier to treat osteomyelitis. However, CSD cement alone when applied at bone defect has some limitation such as its brittleness. The brittleness limits its handling property. Thus, the aim of this study is to fabricate granular CSD cement-gelatin (CSD-Gel) that has good handling property to be used as bone void filler. To prepare CSD-Gel composite, granular CSD was prepared from calcium sulfate hemihydrate (CaSO4.0.5H2O; CSH) and distilled water with water/powder (W/P) ratio of 0.5

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21

Gitelis, Steven, and Gregory T. Brebach. "The Treatment of Chronic Osteomyelitis with a Biodegradable Antibiotic-Impregnated Implant." Journal of Orthopaedic Surgery 10, no. 1 (2002): 53–60. http://dx.doi.org/10.1177/230949900201000110.

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The use of local antibiotics from a biodegradable implant for chronic osteomyelitis is an attractive alternative. The implant delivers high tissue levels, obliterates dead space, aids bone repair and does not need to be removed. The purpose of this paper is to review our early clinical experience with custom-made calcium sulfate (Osteoset bone void filler) antibiotic-impregnated implants.

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22

Jones, Tracey, and Marc Long. "Correlating In-Vitro Dissolution Measurement Methods Used with Bone Void Filler Bioceramics." Key Engineering Materials 254-256 (December 2003): 261–64. http://dx.doi.org/10.4028/www.scientific.net/kem.254-256.261.

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23

Engqvist, Hakan, S. Edlund, Gunilla Gómez-Ortega, Jesper Lööf, and Leif Hermansson. "In Vitro Mechanical Properties of a Calcium Silicate Based Bone Void Filler." Key Engineering Materials 309-311 (May 2006): 829–32. http://dx.doi.org/10.4028/www.scientific.net/kem.309-311.829.

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The objective of the paper is to investigate the mechanical and the handling properties of a novel injectable bone void filler based on calcium silicate. The orthopaedic cement based on calcium silicate was compared to a calcium phosphate cement, Norian SRS from Syntes Stratec, with regard to the working (ejection through 14 G needle) and setting time (Gillmore needles), Young’s modulus and the flexural (ASTM F-394) and compressive (ISO 9917) strength after storage in phosphate buffer saline at body temperature for time points from 1h up to 16 weeks. The calcium silicate cement is composed of

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24

Hoiness, Per R. "Reply to comments on ?The use of a synthetic bone void filler...?" Archives of Orthopaedic and Trauma Surgery 124, no. 10 (2004): 724. http://dx.doi.org/10.1007/s00402-004-0726-x.

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25

Lyons, Frank G., John P. Gleeson, Sonia Partap, Karen Coghlan, and Fergal J. O’Brien. "Novel Microhydroxyapatite Particles in a Collagen Scaffold: A Bioactive Bone Void Filler?" Clinical Orthopaedics and Related Research® 472, no. 4 (2014): 1318–28. http://dx.doi.org/10.1007/s11999-013-3438-0.

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Daculsi, G., M. Durand, T. Fabre, F. Vogt, A. P. Uzel, and J. L. Rouvillain. "Development and clinical cases of injectable bone void filler used in orthopaedic." IRBM 33, no. 4 (2012): 254–62. http://dx.doi.org/10.1016/j.irbm.2012.06.001.

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27

Brooks, Benjamin D., Kristofer D. Sinclair, Sherry N. Davidoff, et al. "Molded polymer-coated composite bone void filler improves tobramycin controlled release kinetics." Journal of Biomedical Materials Research Part B: Applied Biomaterials 102, no. 5 (2013): 1074–83. http://dx.doi.org/10.1002/jbm.b.33089.

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Jones, Zachary, Amanda E. Brooks, Zachary Ferrell, David W. Grainger, and Kristofer D. Sinclair. "A resorbable antibiotic eluting bone void filler for periprosthetic joint infection prevention." Journal of Biomedical Materials Research Part B: Applied Biomaterials 104, no. 8 (2015): 1632–42. http://dx.doi.org/10.1002/jbm.b.33513.

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Gumbiner, Brandon, Elizabeth Jacobsen, Mary Stancukas, and Ngan Nguyen. "A Rare Case of Chondroblastoma with Revision After Graft Rejection." Journal of the American Podiatric Medical Association 107, no. 5 (2017): 440–45. http://dx.doi.org/10.7547/15-216.

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We present a rare case of calcaneal chondroblastoma with subsequent surgical revision after graft rejection in a 13-year-old boy. Complications were encountered after the injectable bone graft filler was placed in the calcaneus after curettage. With noted subsequent sinus tract formation, revision surgery was performed that involved dissection of the sinus tract, removal of bone void filler, and application of demineralized bone matrix sponge human allograft soaked in vancomycin-impregnated saline. Sixteen weeks after the revision surgical intervention, the patient resumed normal athletic acti

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Shilo, Shani, Racheli Gueta, Tamar Harel-Adar, et al. "Innovative Bone Void Filler Putty Based on Recombinant Human Type-I Collagen for Spinal Bone Repair." Spine Journal 11, no. 10 (2011): S147. http://dx.doi.org/10.1016/j.spinee.2011.08.355.

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31

McGee, M., C. Wildenauer, A. Kurmis, E. Margerrison, and J. R. Field. "The utilization of a synthetic bone void filler (JAX) in the repair of a femoral segmental defect." Veterinary and Comparative Orthopaedics and Traumatology 22, no. 02 (2009): 87–95. http://dx.doi.org/10.3415/vcot-08-02-0019.

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Summary Objectives: Currently available synthetic void fillers are indicated for bony voids or gaps that are not intrinsic to the stability of the structure. Jax™ TCP (tricalcium phosphate) is an osteoconductive bioceramic fabricated into 4 mm granules with a unique interlocking form, promoting structural integrity while allowing bone in-growth. The objective of this study was to assess bone ingrowth using a large, critically sized, femoral defect. Methods: A 5 cm segmental ostectomy was created in the mid-diaphysis of 16 adult ovine femora. A stainless steel intramedullary nail was introduced

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Laycock, Phillip, John Cooper, Robert Howlin, Craig Delury, Sean Aiken, and Paul Stoodley. "In Vitro Efficacy of Antibiotics Released from Calcium Sulfate Bone Void Filler Beads." Materials 11, no. 11 (2018): 2265. http://dx.doi.org/10.3390/ma11112265.

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15 different antibiotics were individually mixed with commercially available calcium sulfate bone void filler beads. The antibiotics were: amikacin, ceftriaxone, cefuroxime, ciprofloxacin, clindamycin, colistamethate sodium, daptomycin, gentamicin, imipenem/cilastatin, meropenem, nafcillin, rifampicin, teicoplanin, tobramycin and vancomycin. The efficacy of specific released antibiotics was validated by zone of inhibition (ZOI) testing using a modified Kirby–Bauer disk diffusion method against common periprosthetic joint infection pathogens. With a subset of experiments (daptomycin, rifampin,

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33

Breding, Karin, and Hakan Engqvist. "Strength and Chemical Stability Due to Aging of Two Bone Void Filler Materials." Key Engineering Materials 361-363 (November 2007): 315–18. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.315.

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Injectable resorbable bone cements for bone void fillings are gaining in interest. The materials resorb in vivo with loss of void filling capacity and strength as a consequence. The objective with this study is to qualitative determining the dissolution behaviour for a calcium sulphate and a calcium phosphate cement as function of storage time in different storage medium and correlate to their strength development. Experiments were performed on a calcium phosphate based cement, Norian SRS, and a calcium sulphate based cement, MIIG X3. In the resorbtion study, the materials dissolution at diffe

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Pomrink, G. J., M. P. DiCicco, T. D. Clineff, and E. M. Erbe. "Evaluation of the reaction kinetics of CORTOSSTM, a thermoset cortical bone void filler." Biomaterials 24, no. 6 (2003): 1023–31. http://dx.doi.org/10.1016/s0142-9612(02)00443-x.

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35

Shiels, S. M., R. R. Cobb, K. M. Bedigrew, et al. "Antibiotic-loaded bone void filler accelerates healing in a femoral condylar rat model." Bone & Joint Journal 98-B, no. 8 (2016): 1126–31. http://dx.doi.org/10.1302/0301-620x.98b8.37634.

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36

Voleti, Pramod B., Christopher L. Camp, Alec L. Sinatro, and Joshua S. Dines. "Arthroscopic Removal of Symptomatic Proximal Humerus Locking Plates With Bone-Void Filler Augmentation." Arthroscopy Techniques 5, no. 2 (2016): e343-e346. http://dx.doi.org/10.1016/j.eats.2016.01.009.

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37

Glaeser, Juliane D., Khosrowdad Salehi, Linda EA Kanim, et al. "Electrospun, synthetic bone void filler promotes human MSC function and BMP-2 mediated spinal fusion." Journal of Biomaterials Applications 35, no. 4-5 (2020): 532–43. http://dx.doi.org/10.1177/0885328220937999.

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Introduction Synthetic bone grafts are often used to achieve a well-consolidated fusion mass in spinal fusion procedures. These bone grafts function as scaffolds, and ideally support cell function and facilitate protein binding. Objective The aim was to characterize an electrospun, synthetic bone void filler (Reb) for its bone morphogenetic protein (BMP)-2 release properties and support of human mesenchymal stem cell (hMSC) function in vitro, and its efficacy in promoting BMP-2-/bone marrow aspirate-(BMA)-mediated posterolateral spinal fusion (PLF) in vivo. Methods BMP-2 release kinetics from

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38

Daculsi, G., Marlene Durand, O. Hauger, et al. "Self Hardening Macroporous Biphasic Calcium Phosphate Bone Void Filler for Bone Reconstruction; Animal Study and Human Data." Key Engineering Materials 493-494 (October 2011): 709–13. http://dx.doi.org/10.4028/www.scientific.net/kem.493-494.709.

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Due to the lack of macroporosity in current available Calcium Phosphate cement used in osteoarticular surgery, Micro and Macroporous Biphasic CaP Cement (MCPC™) was developed. The MCPC™ concept was the association of a settable and a fast resorbable matrix and a sieved fraction of microporous biphasic calcium phosphate (BCP) granules, recognized for the high osteoconductive and osteogenic properties. During the resorption of the matrix, a porous structure is created and the osteoconductive effect of the granules promotes the bone ingrowth. A goat preclinical study was realized to evaluate the

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39

McGee, M., R. Stanley, G. Ruthenbeck, et al. "The efficacy of allogeneic mesenchymal precursor cells for the repair of an ovine tibial segmental defect." Veterinary and Comparative Orthopaedics and Traumatology 24, no. 02 (2011): 113–21. http://dx.doi.org/10.3415/vcot-10-03-0046.

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Summary Introduction: Synthetic void-fillers offer an alternative to autograft or allograft bone in the repair of segmental defects. However, the reparative process is delayed as only osteo-conductive elements are present. The inclusion of pluripotential cells may resolve this limitation, and the use of allogeneic tissue provides the opportunity for an off-the-shelf remedy. The current study evaluated the utilisation of mesenchymal precursor cells (MPC) for the repair of an ovine critical-size tibial segmental defect. Methods: Twenty-four, mature female sheep underwent surgery for the creation

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Dumas, Jerald E., Katarzyna Zienkiewicz, Shaun A. Tanner, Edna M. Prieto, Subha Bhattacharyya, and Scott A. Guelcher. "Synthesis and Characterization of an Injectable Allograft Bone/Polymer Composite Bone Void Filler with Tunable Mechanical Properties." Tissue Engineering Part A 16, no. 8 (2010): 2505–18. http://dx.doi.org/10.1089/ten.tea.2009.0672.

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41

E., Erbe, Marx J., Clineff T., and Bellincampi L. "Potential of an ultraporous ?-tricalcium phosphate synthetic cancellous bone void filler and bone marrow aspirate composite graft." European Spine Journal 10 (October 1, 2001): S141—S146. http://dx.doi.org/10.1007/s005860100287.

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42

Karr, Jeffrey C. "Calcium Sulfate/Calcium Phosphate Bone Void Filler in the Treatment of Bilateral Adolescent Unicameral Calcaneal Bone Cysts: 36-Month Follow-Up." Journal of the American Podiatric Medical Association 109, no. 5 (2019): 379–88. http://dx.doi.org/10.7547/17-020.

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A 36-month follow-up of the management of bilateral adolescent unicameral bone cysts in a high school gymnast treated with a calcium sulfate/calcium phosphate (CSCP) bone void filler (BVF) is presented. The more developed left calcaneal cyst was managed with a traditional, open approach consisting of allogenic bone graft, CSCP BVF mixed with platelet-rich plasma. The less developed right calcaneal cyst was managed with a less used approach, a percutaneous bone cortex incision with only the CSCP BVF. The rationale for the selection between the open and percutaneous approaches, long-term BVF inc

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43

Ferrell, Z., DW Grainger, and KD Sinclair. "Antibiotic-eluting resorbable bone-void filler evaluated in a large animal infection prevention model." European Cells and Materials 37 (April 8, 2019): 265–76. http://dx.doi.org/10.22203/ecm.v037a16.

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44

Brooks, Benjamin D. "Comparisons of Release of Several Antibiotics from Antimicrobial Polymer-Coated Allograft Bone Void Filler." International Journal of Biomedical Materials Research 1, no. 2 (2013): 21. http://dx.doi.org/10.11648/j.ijbmr.20130102.11.

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45

Branch, Eric A., Ashley H. Ali, and Christopher E. Baker. "Novel Use of Calcium Phosphate Bone Void Filler in Rotator Cuff and Labral Repair." Techniques in Shoulder & Elbow Surgery 20, no. 1 (2019): 19–25. http://dx.doi.org/10.1097/bte.0000000000000163.

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46

Diaz, Miguel A., Eric A. Branch, Luis A. Paredes, Emily Oakley, and Christopher E. Baker. "Calcium Phosphate Bone Void Filler Increases Threaded Suture Anchor Pullout Strength: A Biomechanical Study." Arthroscopy: The Journal of Arthroscopic & Related Surgery 36, no. 4 (2020): 1000–1008. http://dx.doi.org/10.1016/j.arthro.2019.12.003.

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Jónsson, B. Y., and B. Mjöberg. "Porous titanium granules are better than autograft bone as a bone void filler in lateral tibial plateau fractures." Bone & Joint Journal 97-B, no. 6 (2015): 836–41. http://dx.doi.org/10.1302/0301-620x.97b6.34552.

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Karr, Jeffrey C., and Joseph Lauretta. "In Vitro Activity of Calcium Sulfate and Hydroxyapatite Antifungal Disks Loaded with Amphotericin B or Voriconazole in Consideration for Adjunctive Osteomyelitis Management." Journal of the American Podiatric Medical Association 105, no. 2 (2015): 104–10. http://dx.doi.org/10.7547/0003-0538-105.2.104.

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Abstract:

Background Regarding antibiotic-loaded cements, there is an abundant amount of literature regarding the antibacterial in vitro inhibitory and clinical applications for the treatment of osteomyelitis. The opposite can be said about literature regarding in vitro antifungal-loaded cement drug delivery for the treatment of fungal osteomyelitis. Methods Aspergillus fumigatus and Candida (ATCC 1023ATCC, Manassas, Virginia) were plated on antibiotic/antifungal-free plates. Voriconazole- and amphotericin B–impregnated calcium sulfate and hydroxyapatite (HA) disks, calcium sulfate + HA control disks, a

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Pietrzak, William S., and Barry L. Eppley. "In Vitro Analysis of the Elution of Tobramycin From a Calcium Sulfate Bone Void Filler." Journal of Craniofacial Surgery 15, no. 5 (2004): 752–57. http://dx.doi.org/10.1097/00001665-200409000-00011.

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Tse, Brian K., Zackary D. Vaughn, Derek P. Lindsey, and Jason L. Dragoo. "Evaluation of a one-stage ACL revision Technique using bone void filler after cyclic loading." Knee 19, no. 4 (2012): 477–81. http://dx.doi.org/10.1016/j.knee.2011.06.013.

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