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Dissertations / Theses on the topic 'Bone fracture treatment'

Author: Grafiati

Published: 4 June 2021

Last updated: 16 February 2022

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1

Mills, Leanora Anne. "Fracture non-union epidemiology and treatment." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/23602.

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Introduction Non-union (NU) is a fracture that will not unite. With over one million fractures per annum in the UK long bone non-union has serious social and economical implications. There is little epidemiological data available specifically looking at this NU patient cohort. Studies that are bone specific quote rates of non-union as a proportion of their study group but there is no data quantifying the incidence of NU in the population or per fracture. Studies have highlighted risk factors associated with atrophic non-union including age, diabetes, non-steroidals, and cigarette smoking. Ther

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2

Partanen, J. (Juha). "Etiopathology and treatment-related aspects of hip fracture." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514270959.

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Abstract Hip fracture is a trauma with serious consequences, especially in the elderly. Etiological factors should be known better than nowadays to recognize the individuals at high risk. Also, the treatment of displaced femoral neck fractures has been controversial, and the factors leading to a functional outcome are not known well. The true impact of deep infection on the outcome after hip fracture surgery has also been insufficiently examined. The thesis is based on two etiological studies. In the first study, the geometrical parameters of the upper femur and pelvis in postmenopausal women

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3

Atkins, R. M. "Algodystrophy." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233506.

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4

Bajada, Stefan. "Bone marrow stromal cells for the treatment of established fracture non-union." Thesis, Keele University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536748.

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5

Johnson, Mela Ronelle. "Delivery of BMP-2 for bone tissue engineering applications." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/33830.

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Bone defects and fracture non-unions remain a substantial challenge for clinicians due to a high occurrence of delayed union or non-union requiring surgical intervention. The current grafting procedures used to treat these injuries have many limitations and further long-term complications associated with them. This has resulted in research efforts to identify graft substitution therapies that are able to repair and replace tissue function. Many of these tissue engineered products include the use of growth factors to induce cell differentiation, migration, proliferation, and/or matrix produc

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6

Stoffel, Karl Kilian. "Modern concepts in plate osteosynthesis." University of Western Australia. School of Surgery and Pathology, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0116.

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[Truncated abstract] Renewed interest in the fixation of fractures using plates has been stimulated by an improved understanding of the biology of fracture healing and a drive towards minimally invasive surgery. This has led to a change in the way we use plates nowadays and the way in which we build the bone-plate construct, as well as the development of new implants better suited to these techniques. As a result of this, we have now the potential to safely expand the indications for plate fixation especially in the management of fractures in osteopenic bone. This thesis provides scientific ev

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7

朱月華 and Yuet-wah Chu. "The use of a Chinese medicinal formula (Chuan-Duan-Bu-Gu-San) on experimental fracture healing in a mouse model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31227302.

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8

Vinnars, Bertil. "Scaphoid fractures : Studies on diagnosis and treatment." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8845.

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9

Cueva, Luis Orlando Baselly. "Características da membrana induzida pela técnica de Masquelet em defeito ósseo do rádio em galinhas." Botucatu, 2019. http://hdl.handle.net/11449/182706.

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Orientador: Sheila Canevese Rahal<br>Resumo: O presente estudo visou avaliar temporalmente a formação e a qualidade da membrana induzida de Masquelet, tendo por modelo uma falha óssea segmentar induzida no rádio de galinhas. Foram utilizadas 16 galinhas saudáveis, com um ano de idade e massa corpórea média de 1,45 kg. Sob anestesia geral inalatória, foi induzido defeito segmentar de 1,5 cm no rádio esquerdo, o qual foi preenchido com cimento ósseo na fase pastosa. Os defeitos foram avaliados por meio de exames radiográficos e ultrassonográficos, imediatamente após o procedimento cirúrgico e ao

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10

Roberts, C. A. "Trauma and its treatment in British antiquity : An osteoarchaeological study of macroscopic and radiological features of long bone fractures from the historic period with a comparative study of clinical radiographs." Thesis, University of Bradford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384271.

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11

Davidson, Melissa Anne. "A Pharmacovigilance Approach for Assessing Cardiovascular, Osteological, and Carcinogenic Risk Associated with Thiazolidinedione Drugs Used in the Treatment of Type 2 Diabetes Mellitus." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/38062.

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Diabetes is a chronic and debilitating disease that affects nearly half a billion people worldwide with the vast majority of diabetics suffering from Type 2 diabetes mellitus (T2DM), a disease characterized by insulin insensitivity that often requires pharmacotherapy to effectively maintain target blood sugar levels. The thiazolidinedione (TZD) class of drugs consists of oral hypoglycaemic agents used alone or in combination with other antidiabetic drugs to treat T2DM. The drugs within this class, which include rosiglitazone and pioglitazone, were originally heralded as providing novel first a

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12

Caruthers, William A. "Bisphosphonates and Bone Microdamage." UKnowledge, 2012. http://uknowledge.uky.edu/cbme_etds/4.

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Osteoporosis is a significant healthcare issue due to the increasing elderly population. Bisphosphonates are used to treat osteoporosis by reducing the rate of resorption, increasing bone mineral density (BMD) and thereby reducing fracture risk. Long-term bisphosphonate treatment, however, has been associated with low-energy fractures. Bone microdamage may provide a partial explanation for one of the mechanisms responsible for these fractures since it has been shown to reduce bone toughness, fracture resistance, and bone strength. The goal of this study was to quantify the changes in bone micr

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13

Bruni, Maëlys. "Relação entre a tríade da mulher e a ocorrência de lesões músculo-esqueléticas em jovens desportistas: prevenção da tríade da atleta - revisão bibliográfica." Bachelor's thesis, [s.n.], 2018. http://hdl.handle.net/10284/6727.

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Projeto de Graduação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em Fisioterapia<br>Objetivo: Estabelecer uma relação entre a tríada feminina com as lesões músculo-esqueléticas nas atletas femininas. Metodologia: pesquisa computorizada nas bases de dados PubMed, Google scholar e Scielo para identificar estudos que analisassem as relações entre a tríade e a ocorrência de lesões nas jovens desportistas seguindo os critérios de inclusão definidos para o estudo. Foi realizada a análise de qualidade com recurso à escala Critical Appraisal

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14

Gracitelli, Mauro Emilio Conforto. "Estudo randomizado da osteossíntese das fraturas da extremidade proximal do úmero com placa ou haste intramedular." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5140/tde-24022016-091653/.

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INTRODUÇÃO: As fraturas da extremidade proximal do úmero são frequentes, com incidência crescente no idoso e com impacto na qualidade de vida e na função do ombro. Para os casos com desvio, a placa bloqueada é o método mais utilizado de osteossíntese. Bons resultados clínicos são obtidos tanto com a placa bloqueada como com a haste intramedular bloqueada. O objetivo do estudo foi a comparação desses métodos no tratamento das fraturas da extremidade proximal do úmero quanto aos resultados clínicos, radiográficos e à taxa de complicações. MÉTODOS: Nesse estudo clínico prospectivo e randomizado,

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15

Silva, Fernando Brandão de Andrade e. "Estudo clínico comparativo, prospectivo e randomizado das osteossínteses da clavícula com placa ou haste intramedular flexível." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/5/5140/tde-24102014-152044/.

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INTRODUÇÃO: As fraturas do terço médio da clavícula representam 80% das fraturas claviculares e seu tratamento é motivo de discussão na literatura ortopédica. Estudos prévios relativos ao tratamento cirúrgico têm demonstrado bons resultados clínicos com o uso das placas de reconstrução ou a fixação intramedular elástica estável com hastes flexíveis de titânio. O objetivo deste estudo foi a comparação desses métodos no tratamento das fraturas do terço médio da clavícula, quanto aos resultados funcionais, parâmetros radiográficos, dor pós-operatória, taxa de satisfação e taxa de complicações. MÉ

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16

Leslie, Shirae. "The controlled release of rat adipose-derived stem cells from alginate microbeads for bone regeneration." Thesis, Georgia Institute of Technology, 2013. http://hdl.handle.net/1853/48946.

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Cell-based therapies have potential for tissue regeneration but poor delivery methods lead to low viability or dispersal of cells from target sites, limiting clinical utility. Here, we developed a degradable and injectable hydrogel to deliver stem cells for bone regeneration. Alginate microbeads <200µm are injectable, persist at implantation sites and contain viable cells, but do not readily degrade in-vivo. We hypothesized that controlled release of rat adipose-derived stem cells (ASCs) from alginate microbeads can be achieved by incorporating alginate-lyase in the hydrogel. Microbeads were f

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17

Sinikumpu, J. J. (Juha-Jaakko). "Forearm shaft fractures in children." Doctoral thesis, Oulun yliopisto, 2013. http://urn.fi/urn:isbn:9789526203003.

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Abstract There are previous reports of an increasing incidence of children’s forearm fractures in the last few decades. Their surgical treatment is evolving. The present study was aimed at determining the incidence and background of these fractures and their treatment. It was also aimed to analyse the short- and long-term outcomes. A comprehensive population-based study (N=168) among 86,000 children in Oulu University Hospital District over a decade (2000–2009) was performed to analyse the incidence of middle-third forearm fractures. Further data (N=291) covering 1997–2009 was achieved in orde

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18

Brizola, Evelise Silva. "Estudo clínico e molecular em indivíduos com osteogênese imperfeita e análise do tratamento com bifosfonados." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2015. http://hdl.handle.net/10183/131163.

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A Osteogênese Imperfeita (OI) é uma doença genética do tecido conjuntivo caracterizada por fragilidade óssea e susceptibilidade à fratura sob mínimo ou nenhum trauma. O objetivo deste trabalho foi estudar características clínicas e moleculares de crianças e adultos com Osteogênese Imperfeita e analisar o efeito do tratamento medicamentoso com bifosfonados em relação aos biomarcadores metabólicos e ósseos em pacientes adultos. Esta tese se dividiu em dois capítulos onde 1) foi realizado um estudo retrospectivo sobre as características clínicas no momento do diagnóstico de OI, com ênfase nas car

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19

Reed, Suzanne Rene. "Epidemiology of joint injuries in thoroughbred racehorses in training." Thesis, Royal Veterinary College (University of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.559071.

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20

López, Alejandro. "Injectable Biomaterials for Spinal Applications." Doctoral thesis, Uppsala universitet, Institutionen för teknikvetenskaper, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-215606.

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The use of injectable biomaterials is growing as the demands for minimally invasive procedures, and more easily applicable implants become higher, but their availability is still limited due to the difficulties associated to their design. Each year, more than 700,000 vertebral compression fractures (VCF’s) are reported in the US and 500,000 VCF’s in Europe due to primary osteoporosis only. VCF’s can compromise the delicacy of the spinal canal and also cause back pain, which affects the patient’s quality of life. Vertebroplasty was developed in the 80’s, and has proven to be a safe minimally in

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21

Drago, Manuela Aleluia. "Placa de osso bovino na osteossíntese de tíbia de coelhos: avaliação biomecânica ex-vivo." Universidade Federal do Espírito Santo, 2011. http://repositorio.ufes.br/handle/10/5097.

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Made available in DSpace on 2016-08-29T15:37:22Z (GMT). No. of bitstreams: 1 tese_5256_.pdf: 375211 bytes, checksum: 832eb7716f5f86a3d232c597e8e95ae1 (MD5) Previous issue date: 2011-09-06<br>O uso de materiais produzidos a partir de osso bovino tem sido proposto na confecção de implantes como pinos, placas e parafusos, por promoverem as mesmas funções de um enxerto ósseo, ou seja, serem osteoindutores e osteocondutores. Entretanto, aspectos estruturais e mecânicos devem ser estudados previamente ao uso in vivo de implantes de osso. Portanto, o objetivo desse estudo foi avaliar o comportame

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22

Pohl, Anthony P. "A new design of external fixator for long bone fracture management." 1999. http://web4.library.adelaide.edu.au/theses/09MD/09mdp748.pdf.

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Bibliography: leaves 216-231. Examines the sliding capability of external fixators under load and describes the development and testing of an external fixator capable of providing axial cyclic motion to a fracture site while a patient is walking.

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23

"Does low-magnitude high-frequency vibration enhance bone remodeling in fracture healing?" 2010. http://library.cuhk.edu.hk/record=b5894449.

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Chow, Dick Ho Kiu.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2010.<br>Includes bibliographical references (leaves 93-103).<br>Abstracts in English and Chinese.<br>Abstract --- p.ii<br>Publications --- p.vii<br>Acknowledgement --- p.viii<br>Table of Contents --- p.x<br>List of Figures --- p.xiv<br>List of Tables --- p.xv<br>List of Abbreviations --- p.xvii<br>Chapter 1 --- Introduction --- p.1<br>Chapter 1.1 --- Bone and its Cellular Components --- p.1<br>Chapter 1.1.1 --- Cellular Components of Bone --- p.1<br>Chapter 1.1.2 --- Macroscopic Structure --- p.4<br>Chapter 1.

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"Effect of low-magnitude high-frequency vibration on fracture healing in normal and osteoporotic bones." Thesis, 2008. http://library.cuhk.edu.hk/record=b6074585.

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Bone fracture, particularly that occurring in osteoporotic conditions, has become a major health issue. Fracture healing is a well-orchestrated regenerative process, the enhancement of which has been one of the major goals in fracture management. Low-magnitude high-frequency vibration (LMHFV) is osteogenic for intact bone and beneficial for limb blood circulation, which implies a potential of enhancement for fracture healing. Three parts of the experiments were conducted in this study to test the hypothesis that LMHFV would accelerate fracture healing by promoting chondrogenesis, endochondral

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25

"Elderly women with osteoporotic fracture: from clinical and biochemical assessments, bone density studies to bisphosphonate treatment." 2000. http://library.cuhk.edu.hk/record=b5890448.

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Or Pui Ching.<br>Thesis submitted in: December 1999.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2000.<br>Includes bibliographical references (leaves 174-201).<br>Abstracts in English and Chinese.<br>acknowledgement --- p.i<br>abstract (english version) --- p.ii<br>abstract (chinese version) --- p.vii<br>table of contents --- p.xi<br>abbreviations --- p.xvi<br>list of tables --- p.xviii<br>list of figures --- p.xxii<br>Chapter chapter 1. --- introduction --- p.1<br>Chapter chapter 2. --- literature review --- p.3<br>Chapter 2.1. --- Bone structure --- p.3<br>Chapter 2.1.1.

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26

"A study of the enhancement effects of low-intensity pulsed ultrasound on fracture healing at different angles of applications with a rat model." 2008. http://library.cuhk.edu.hk/record=b5893565.

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Chung, Shu Lu.<br>Thesis (M.Phil.)--Chinese University of Hong Kong, 2008.<br>Includes bibliographical references (leaves 109-118).<br>Abstracts in English and Chinese.<br>Abstract --- p.i-iv<br>中文摘要 --- p.v-vii<br>Publications --- p.viii<br>Acknowledgements --- p.ix<br>List of Abbreviations --- p.x-xi<br>Index for Figures --- p.xii-xiv<br>Index for Tables --- p.xv<br>Table of Contents --- p.xvi-xix<br>Chapter Session 1: --- Introduction --- p.1<br>Chapter 1.1 --- Biology of fracture healing process --- p.2<br>Chapter 1.1.1 --- Stage of inflammation --- p.2-3<br>Chapter 1.1.2 --- St

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27

"The effectiveness of an educational intervention on pain management and post-operative outcomes of Chinese patients with fracture limb." Thesis, 2009. http://library.cuhk.edu.hk/record=b6074725.

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Aim. The overall aims of this study were to develop a tailor-made educational intervention and to examine its effectiveness on short- and longer-term outcomes among Chinese patients with traumatic limb fractures who had undergone surgery.<br>Background. Fracture limb and undergoing surgery is the common problem after injury. It is the most common source of pain and anxiety and research continues to demonstrate a high prevalence of unrelieved pain in injured patients who have undergone surgery. Patient's belief in pain is the major barrier in pain management. Strategies directed to have appropr

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28

"Effects of low magnitude high frequency vibration on blood flow and angiogenesis during fracture healing in normal and osteoporotic bones." Thesis, 2011. http://library.cuhk.edu.hk/record=b6075508.

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Sun, Minghui.<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2011.<br>Includes bibliographical references (leaves 125-159).<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Abstract also in Chinese.

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29

Chou, Ying Chao, and 周應照. "Combination of the biodegradable stent mimicking as periosteum and the nanofibous membrane for sustainable release of lidocaine for effective and painless treatment of a segmental long bone fracture with periosteal stripping injury." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/3vdu3u.

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30

Bai, Shao Han, and 白少涵. "Biomechanical Study for Treatment of Unstable Trochanteric Fractures with Osteoporotic Bone- Comparison between a PMMA Cemented DHS and an Intramedullary Device." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/13121303302144789807.

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碩士<br>長庚大學<br>醫療機電工程研究所<br>101<br>Interochanteric fractures associated with severe osteoporosis and comminution remain a considerable challenge to orthopedic surgeon. The standard treatment of these fractures is by osteosynthesis with a dynamic hip screw (DHS). However, in unstable intertrochanteric fractures, complications of cut-out and excessive sliding of the lag screw occurred frequently. Another device frequently used to treat these unstable intertrochanteric fractures is the use of a intramedullary nail. Although PMMA bone cement has been widely applied as a secondary fixation to facili

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Tanjung, Nancy Giovanni. "In Vitro and In Silico Analysis of Osteoclastogenesis in Response to Inhibition of De-phosphorylation of EIF2alpha by Salubrinal and Guanabenz." Thesis, 2013. http://hdl.handle.net/1805/5189.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>An excess of bone resorption over bone formation leads to osteoporosis, resulting in a reduction of bone mass and an increase in the risk of bone fracture. Anabolic and anti-resorptive drugs are currently available for treatment, however, none of these drugs are able to both promote osteoblastogenesis and reduce osteoclastogenesis. This thesis focused on the role of eukaryotic translation initiation factor 2 alpha (eIF2alpha), which regulates efficiency of translational initiation. The elevation of phosphorylated eIF2alpha was rep

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32

Tanas, Francesco. "Tratamento das fraturas condilares e subcondilares." Master's thesis, 2017. http://hdl.handle.net/10284/6338.

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A traumatologia é uma das patologias mais frequentes da área maxilo e crânio facial. Este trabalho tem como objecto o estudo das fracturas condilares, a classificação delas e o tratamento conservador e médico-cirurgico, através da utilização de vários tipos de placas de fixação (rétas, trapezoidais, a lambda ou y, e a grelha). Para a realização desta revisão foram consultados vários textos e artigos científicos sobre o argumento, utilizando as seguintes palavras-chave: “fraturas condilares”, “fraturas subcondilares”, “tratamento cirurgico das fraturas condilares”, “placas de titânio”, “o

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