Relevant bibliographies by topics / Bone fracture treatment

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
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Academic literature on the topic 'Bone fracture treatment'

Author: Grafiati
Published: 4 June 2021
Last updated: 16 February 2022

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Journal articles on the topic "Bone fracture treatment"

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SILVA, JONATHAN RIBEIRO DA, CARLOS FERNANDO DE ALMEIDA BARROS MOURÃO, HERNANDO VALENTIM DA ROCHA JÚNIOR, LUIZ FERNANDO MAGACHO, GUTO FIDALGO DAUMAS MORAES, and NICOLAS HOMSI. "Treatment of frontal bone fracture sequelae through inversion of the bone fragment." Revista do Colégio Brasileiro de Cirurgiões 43, no. 6 (December 2016): 472–75. http://dx.doi.org/10.1590/0100-69912016006011.

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ABSTRACT Treatment of frontal sinus fractures depends on the structures involved: the anterior wall, the posterior wall and the nasofrontal duct. It may vary from the correction of the defect in the anterior wall to the cranialization with obliteration of the nasofrontal duct. The inversion of the frontal sinus's anterior wall to correct the defect in the fractured region is a good treatment option for sequelae, since this technique eliminates or reduces the use of biomaterial in the area, and allows direct assessment of the permeability of the nasofrontal duct. This work describes the technique of fractured segment inversion for the treatment of frontal sinus fracture sequelae in a motorcycle accident victim.
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Kumar, B. S. Vijaya. "Treatment of diaphyseal fractures of tibia with intramedullary interlocking nail." International Journal of Research in Orthopaedics 5, no. 5 (August 26, 2019): 783. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20193130.

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<p class="abstract"><strong>Background:</strong> The tibia, or shinbone, is the most commonly fractured long bone in the body. A tibial shaft fracture occurs along the length of the bone, below the knee and above the ankle. It typically takes a major force to cause this type of broken leg. Motor vehicle collisions, for example, are a common cause of tibial shaft fractures. In many tibia fractures, the smaller bone in the lower leg (fibula) is broken as well. The objective was to study fracture healing and union rates with closed intra-medullary interlocking nailing.</p><p class="abstract"><strong>Methods:</strong> Patients of both sexes belonging to adult age group presenting with fracture tibia to Orthopedic Department, Vydehi Institute of Medical Sciences, of are admitted from January 2015 to December 2015.<strong></strong></p><p class="abstract"><strong>Results:</strong> In the present study maximum number of patients belongs to 18 to 27 years age group (18 cases) followed by 28 to 37 years age group (15 cases), maximum number of patients sustained tibia fracture due to RTA (38 cases) followed by fall (12 cases), maximum number of patients sustained simple tibia fracture (32 cases), followed by type 2 compound tibia fracture (13 cases) and 36 patients had excellent functional results and 8 patients had good functional outcome, while only 4 patients had fair functional outcome.</p><p class="abstract"><strong>Conclusions:</strong> IM rods are secured within the bone by screws both above and below the fracture. The metal screws and the rod can be removed if they cause problems, but can also be left in place for life. Tibial rodding provides excellent fixation and alignment of the bones.</p>
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Moldovan, Flaviu, Adrian Gligor, and Tiberiu Bataga. "Structured Integration and Alignment Algorithm: A Tool for Personalized Surgical Treatment of Tibial Plateau Fractures." Journal of Personalized Medicine 11, no. 3 (March 10, 2021): 190. http://dx.doi.org/10.3390/jpm11030190.

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The planning of the surgical treatment in orthopedics, with the help of three-dimensional (3D) technologies, arouses an increasing scientific interest. Scientific literature describes some semi-automatic reconstructive attempts at fragmented bone fractures, but the matching algorithms presented are likely to improve. The aim of this paper is to develop a new method of aligning fragments of comminutive fractures. We have created a structured integration process and an alignment algorithm integrated in a clinical workflow for personalized surgical treatment of fractures. The provided solution is able to align the surfaces of bone fragments derived from the segmentation process of volumetric tomographic data. Positional uncertainties are eliminated interactively by the user, who selects the corresponding pairs of fracture surfaces. The final matching and the right alignment are performed automatically by the innovative alignment algorithm. The paper solves a challenging problem for the reconstruction of fractured bones, namely the choice of the optimal matching option from the situation in which surface portions of a fracture fragment correspond to multiple high fragments. The method is validated in practice for preoperative planning of a 49-year-old male patient who had a tibial plateau fracture of Schatzker type VI.
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Mohiuddin, M., M. Hasan, M. Shohag, R. N. Ferdousy, M. M. Alam, and N. S. Juyena. "Surgical management of limb fractures in calves and goats." Bangladesh Veterinary Journal 52, no. 1-4 (December 25, 2018): 46–56. http://dx.doi.org/10.32856/bvj-2018.06.

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The study was conducted to determine the occurrence of fractures in calves and goats at Veterinary Teaching Hospital (VTH), Bangladesh Agricultural University (BAU) and to compare the efficacy of fracture treatment with external and internal fixation using splints and bone plate/wire suture respectively. Patients brought to VTH with the history of automobile accident, trauma and clinical signs suggestive of fractures were subjected to detailed physical, orthopaedic and radiographic examinations to confirm fractures. A total of 6 calves and 4 Black Bengal goats were presented to VTH with limb fractures. Fractures were treated with close reduction and external fixation with splints and bandage, and open reduction and internal fixation with wire suture and bone plate. 50% and 75% fracture cases healed properly in calves and goats respectively. Among the affected animals, 60% were females irrespective of species. Metacarpal bone was the most susceptible for limb fracture. Three were open fractures and 7 cases were closed fracture with the occurrence of 70%. The healing percentage of open fracture treated with external fixation was very poor and amputation was needed in the fractured limb. Overall treatment success rate was 60 %. Biochemical analysis revealed very significant (p<0.01) difference in serum calcium level before and after healing due to hard callus formation. This study shows that bone plating fixation give a satisfactory results to calves with fracture. Moreover, the study could help veterinarians to set up proper treatment method depending on location of fracture.
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Davies, Michael. "Non HRT Options for the Treatment of Osteoporosis." British Menopause Society Journal 4, no. 3 (September 1998): 96–101. http://dx.doi.org/10.1177/136218079800400306.

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Osteoporosis is now a treatable condition with an abundance of evidence for the efficacy of certain therapeutic strategies in preventing recurrent fractures. Most of these treatments act by improving bone mineral density through inhibition or reduction of bone resorption. For those women who are unable to take HRT; bisphosphonates, calcium, vitamin D, calcitriol or calcitonin may confer certain benefits. The bisphosphonate alendronate reduces both vertebral and long bone fractures, an effect seen soon after starting treatment. The changes in BMD and fracture reduction are less with the use of etidronate but it is certainly beneficial in reducing recurrent vertebral fracture. In the elderly calcium and vitamin D in combination can reduce non-vertebral and hip fracture and supplemental calcium of 1 g/day has been predicted to reduce bone loss and thus hip fractures by 22%. Evidence that calcitriol or calcitonin reduce fracture incidence is not good but calcitonin has been shown to have analgesic properties in those with acute vertebral fracture. The role of calcitriol is less certain and should be reserved for women with vertebral fractures in whom HRT or bisphosphonates cannot be used.
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Tkacheva, Olga N., Natalia V. Brailova, Ekaterina N. Dudinskaya, and Veronika A. Kuznesova. "Osteoporosis drug treatment after fracture." Osteoporosis and Bone Diseases 23, no. 4 (June 6, 2021): 30–36. http://dx.doi.org/10.14341/osteo12694.

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The prevalence of osteoporosis, especially among the elderly, is increasing exponentially, leading to an increase in the number of fractures and disability. As a result, new requirements for anti-osteoporotic therapy appear, associated with its influence not only on the remodeling of healthy bone, but also on the acceleration of fracture consolidation. The article provides a brief overview of the effect of various anti-osteoporotic drugs on the healing of bone fractures. An assessment of the consolidating effect of antiresorptive drugs — bisphosphonates and denosumab, and anabolic drug — teriparatide, monoclonal antibodies blocking the protein sclerostin, strontium ranelate is given. The use of antiresorptive drugs did not affect, according to the literature, the slowing down of consolidation after fractures of various parts of the skeleton (hip, vertebrae, distal radius). The introduction of anabolic drugs, in particular teriparatide, is accompanied by faster healing of fractures in comparison with the timing of natural bone regeneration or the intake of bisphosphonates, causing an improvement in the formation of callus. The use of drugs that block sclerostin also increases bone formation and bone strength. Based on the available data, it can be concluded that fractures should not be considered as a contraindication to the use of these drugs and be the reason for the late initiation of drug treatment of osteoporosis.
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Lukošiūnas, Algirdas, Ričardas Kubilius, Gintautas Sabalys, Tadas Keizeris, and Dalius Sakavičius. "An Analysis of Etiological Factors for Traumatic Mandibular Osteomyelitis." Medicina 47, no. 7 (July 28, 2011): 380. http://dx.doi.org/10.3390/medicina47070054.

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Objective. The aim of this study was to analyze the factors that were associated with the development of osteomyelitis during the treatment of mandibular fractures. Material and Methods. The data of 3188 patients with mandibular fractures treated during 2002–2009 were analyzed. Traumatic osteomyelitis of the mandible was diagnosed in 207 patients. The background factors of complications were studied and compared with the control group (100 patients) not having complications after treatment of mandibular fractures. The data of clinical, roentgenologic, microbiological, and immunological investigations were analyzed. A logistic regression model was developed to identify the factors for osteomyelitis development. Results. The treatment in 6.5% of patients was complicated with osteomyelitis; 88.5% of these patients were men, and more than 80% of patients were younger than 50 years. In 86.8% of cases, Staphylococcus species were isolated, with Staphylococcus aureus accounting for 69.1% of cases. The following factors were found to be associated with osteomyelitis development: immunity dysfunction, caries-affected teeth at the fracture line, mobile fractured bones, bone fixation after more than 7 days following trauma, healthy teeth at the fracture line, insufficient bone reposition, and bone fixation after 3–7 days following trauma. Conclusion. Comparative analysis of factors influencing the treatment results revealed a great importance of immunological and dental status and microflora at the affected site. Insufficient or late reposition and fixation of fractured bone fragments play a significant role in the healing process.
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Gajdobranski, Djordje, Dragoljub Zivanovic, Aleksandra Mikov, Andjelka Slavkovic, Dusan Maric, Zoran Marjanovic, and Vukadin Milankov. "Scaphoid fractures in children." Srpski arhiv za celokupno lekarstvo 142, no. 7-8 (2014): 444–49. http://dx.doi.org/10.2298/sarh1408444g.

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Introduction. Scaphoid fractures are rare in childhood. Diagnosis is very difficult to establish because carpal bones are not fully ossified. In suspected cases comparative or delayed radiography is used, as well as computerized tomography, magnetic resonance imaging, ultrasound and bone scintigraphy. Majority of scaphoid fractures are treated conservatively with good results. In case of delayed fracture healing various types of treatment are available. Objective. To determine the mechanism of injury, clinical healing process, types and outcome of treatment of scaphoid fractures in children. Methods. We retrospectively analyzed patients with traumatic closed fracture of the scaphoid bone over a ten-year period (2002-2011). The outcome of the treatment of ?acute? scaphoid fracture was evaluated using the Mayo Wrist Score. Results. There were in total 34 patients, of mean age 13.8 years, with traumatic closed fracture of the scaphoid bone, whose bone growth was not finished yet. Most common injury mechanism was fall on outstretched arm - 76% of patients. During the examined period 31 children with ?acute? fracture underwent conservative treatment, with average immobilization period of 51 days. Six patients were lost to follow-up. In the remaining 25 patients, after completed rehabilitation, functional results determined by the Mayo Wrist Score were excellent. Conclusion. Conservative therapy of ?acute? scaphoid fractures is an acceptable treatment option for pediatric patients with excellent functional results.
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Cederholm, Tommy, and Margareta Hedström. "Nutritional treatment of bone fracture." Current Opinion in Clinical Nutrition and Metabolic Care 8, no. 4 (July 2005): 377–81. http://dx.doi.org/10.1097/01.mco.0000172576.48772.a8.

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Vucetic, Cedomir, Borislav Dulic, Zoran Vukasinovic, Goran Tulic, Nevena Kalezic, and Aleksandar Todorovic. "The treatment of subtrochanteric fractures." Srpski arhiv za celokupno lekarstvo 139, no. 7-8 (2011): 540–47. http://dx.doi.org/10.2298/sarh1108540v.

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Subtrochanteric fractures of the femur have a special place because of a significant number of complications following treatment. Powerful loading forces asymmetrically acting to this bone segment, as well as poor vascularization interfere with bone union. There are basically two current approaches in the fixation of subtrochanteric fractures; the first involves a plate with a compression screw and another one is intramedullary (IM) nail, with two options: centromedullary (standard interlocking femoral nail) and cephalomedullary femoral nail with two modifications, reconstructive and trochanteric. All IM nails may be used by open technique or closed minimal invasive method. IM nailing is favoured in view of a shorter operative time, shorter hospitalisation and complications. Indirect fracture reduction and knowledge of biology of bone fracture may result in full success without any bone graft.
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Dissertations / Theses on the topic "Bone fracture treatment"

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Mills, Leanora Anne. "Fracture non-union epidemiology and treatment." Thesis, University of Edinburgh, 2016. http://hdl.handle.net/1842/23602.

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Introduction Non-union (NU) is a fracture that will not unite. With over one million fractures per annum in the UK long bone non-union has serious social and economical implications. There is little epidemiological data available specifically looking at this NU patient cohort. Studies that are bone specific quote rates of non-union as a proportion of their study group but there is no data quantifying the incidence of NU in the population or per fracture. Studies have highlighted risk factors associated with atrophic non-union including age, diabetes, non-steroidals, and cigarette smoking. There is scientific interest regarding how best to classify non-unions and the role of biological agents in treating them. Aims • To quantify the incidence of non-union in a large population and calculate the risk of non-union per fracture according to age, sex and anatomical distribution. • To assess the causes contributing to non-union and outcomes of treatment in a non-union cohort and validate a new non-union scoring system. • To test the treatment potential of a novel molecule (monobutyrin) and a growth factor in a small animal model of non-union. Method • Using the ICD-10 data from the Scottish population as collected by NHS Scotland the incidence of non-union and fractures were calculated. • A cohort of 100 non-union patients were studied for risk factors associated with their non-union, treatment outcome and to assess a new NU classification system. • A rat model of tibial non-union was used to assess the potential of monobutyrin and BMP-2 in treating non-union in an animal model. Results • Fracture non-union is very rarely found in children (1 in 500 fractures) and occurs in up to 1 in 50 adult fractures. Non-union of a fracture has a significantly higher risk in young adults than the elderly by about 3 fold. Osteoporosis may not be a risk for non-union. The tibia and clavicle are the sites with the greatest potential for fracture non-union. • Non-union is multifactorial in two out of three patients. Biomechanical stability, patient host factors and infection must all be considered in every patient. Occult or unexpected recurrent infection is present in up to 10% of patients. When all factors are considered in treatment the outcome is 95% successful with 88% requiring 2 or less procedures to heal the non-union and only a minority requiring adjuvant graft or biological agents. The proposed new classification system is complex and did not clearly identify those patients who would require adjuvant treatment (eg bone grafting or BMP) or those likely to have unsuccessful non-union treatment. • Monobutyrin and BMP-2 when tested on the small animal non-union model did not improve the success rate of union. Conclusions Non-union affects approximately 1000 people per year in Scotland, this figure is not as high as 5-10% of all fractures. It is associated with fractures in young adults and of the clavicle and tibia, treatment can have a very high success rate without the need for adjuvant biological polytherapy when all contributing factors are considered and managed appropriately. A new non-union classification needs to incorporate the multifactorial aspects of non-union without being too complex to use in everyday clinical situations.
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Partanen, J. (Juha). "Etiopathology and treatment-related aspects of hip fracture." Doctoral thesis, University of Oulu, 2003. http://urn.fi/urn:isbn:9514270959.

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Abstract Hip fracture is a trauma with serious consequences, especially in the elderly. Etiological factors should be known better than nowadays to recognize the individuals at high risk. Also, the treatment of displaced femoral neck fractures has been controversial, and the factors leading to a functional outcome are not known well. The true impact of deep infection on the outcome after hip fracture surgery has also been insufficiently examined. The thesis is based on two etiological studies. In the first study, the geometrical parameters of the upper femur and pelvis in postmenopausal women with hip fracture were (n=70) compared to age-adjusted controls (n=40). Measurements were made from position-standardized and calibrated pelvic plain x-rays. The differences between the two different types of hip fracture, femoral neck fractures (n=46) and trochanteric fractures (n=24) were also defined. High femoral neck/shaft angle (NSA), thin femoral cortices, low femoral shaft diameter (FSD) and trochanter width and the pelvic dimensions associate strongly with the hip fracture risk in postmenopausal women. Greater NSA, smallest outer pelvic diameter and acetabular width, narrower FSD and smaller femoral neck/shaft cortex ratio were associated with femoral neck fracture rather than trochanteric fracture in postmenopausal women. In the second study, lifetime factors, some bone metabolism markers and bone mineral density were analyzed from postmenopausal women (n=74; 49 with femoral neck fracture, 25 with trochanteric fracture) and age-adjusted controls (n=40). Impaired functional ability, use of loop diuretics, antidiabetic, antidepressant and neuroleptic drugs, some concurrent diseases, such as stroke, diabetes, malignancy, cardiovascular diseases, low bone mineral density of the upper femur, low serum calcium, low serum 25-hydroxyvitamin D and high serum calcitonin, seem to be related to the risk of hip fracture, while low bone mineral density and low serum calcitonin are related to the trochanteric type of fracture in postmenopausal women. The treatment of displaced femoral fractures included two prospective case-control studies, and the first of these involved a comparison (357 matched pairs) of patients with osteosynthesis (OS) with two pins in Lund and patients with uncemented hemiarthroplasty (HA) in Oulu. The patients treated with OS had 4 months after fracture better ambulatory capacity, used walking aids less often and had less pain than the patients treated with HA. The other comparison (84 matched pairs) was made between OS with three screws and uncemented HA, and it revealed no significant differences between HA and OS in the short-term functional outcome. Both studies revealed a higher re-operation rate in OS patients than uncemented HA patients. The case-control study with 29 matched pairs showed that deep infection after a hip fracture operation impairs the short-term functional outcome and slightly increases mortality, with an attributable mortality rate of 10 %. In conclusion, this thesis suggests that the geometry of the upper femur and pelvis, the aforesaid lifetime factors, the aforesaid metabolism markers and bone mineral density are associated with the etiopathology and type of hip fracture in postmenopausal women. The short-term functional outcome was better in OS patients treated with two pins compared to uncemented HA, but the higher re-operation rate should be considered among the OS patients. Deep infection is a serious complication of hip fracture surgery, which impairs function and increases mortality.
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Atkins, R. M. "Algodystrophy." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233506.

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Bajada, Stefan. "Bone marrow stromal cells for the treatment of established fracture non-union." Thesis, Keele University, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.536748.

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Johnson, Mela Ronelle. "Delivery of BMP-2 for bone tissue engineering applications." Diss., Georgia Institute of Technology, 2010. http://hdl.handle.net/1853/33830.

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Bone defects and fracture non-unions remain a substantial challenge for clinicians due to a high occurrence of delayed union or non-union requiring surgical intervention. The current grafting procedures used to treat these injuries have many limitations and further long-term complications associated with them. This has resulted in research efforts to identify graft substitution therapies that are able to repair and replace tissue function. Many of these tissue engineered products include the use of growth factors to induce cell differentiation, migration, proliferation, and/or matrix production. However, current growth factor delivery methods are limited by poor retention of growth factors upon implantation resulting in low bioactivity. These limiting factors lead to the use of high doses and frequent injections, putting the patients at risk for adverse effects. The goal of this work was to develop and evaluate the efficacy of BMP-2 delivery systems to improve bone regeneration. We examined two approaches for delivery of BMP-2 in this work. First, we evaluated the use of a self-assembling lipid microtube system for the sustained delivery of BMP-2. We determined that sustained delivery of BMP-2 from the lipid microtube system was able to enhance osteogenic differentiation compared to empty microtubes, however did not demonstrate a significant advantage compared to a bolus BMP-2 dose in vitro. Second, we developed and assessed the functionality of an affinity-based system to sequester BMP-2 at the implant site and retain bioactivity by incorporating heparin within a collagen matrix. Incorporation of heparin in the collagen matrix improved BMP-2 retention and bioactivity, thus enhancing cell-mediated mineralized matrix deposition in vitro. Lastly, the affinity-based BMP-2 delivery system was evaluated in a challenging in vivo bone repair model. Delivery of pre-bound BMP-2 and heparin in a collagen matrix resulted in new bone formation with mechanical properties not significantly different to those of intact bone. Whereas delivery of BMP-2 in collagen or collagen/heparin matrices had similar volumes of regenerated mineralized tissue but resulted in mechanical properties significantly less than intact bone properties. The work presented in this thesis aimed to address parameters currently preventing optimal performance of protein therapies including stability, duration of exposure, and localization at the treatment site. We were able to demonstrate that sustained delivery of BMP-2 from lipid microtubes was able to induce osteogenic differentiation, although this sustained delivery approach was not significantly advantageous over a bolus dose. Additionally, we demonstrated that the affinity-based system was able to improve BMP-2 retention within the scaffold and in vitro activity. However, in vivo implantation of this system demonstrated that only delivery of pre-complexed BMP-2 and heparin resulted in regeneration of bone with mechanical properties not significantly different from intact bone. These results indicate that delivery of BMP-2 and heparin may be an advantageous strategy for clinically challenging bone defects.
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Stoffel, Karl Kilian. "Modern concepts in plate osteosynthesis." University of Western Australia. School of Surgery and Pathology, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0116.

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[Truncated abstract] Renewed interest in the fixation of fractures using plates has been stimulated by an improved understanding of the biology of fracture healing and a drive towards minimally invasive surgery. This has led to a change in the way we use plates nowadays and the way in which we build the bone-plate construct, as well as the development of new implants better suited to these techniques. As a result of this, we have now the potential to safely expand the indications for plate fixation especially in the management of fractures in osteopenic bone. This thesis provides scientific evidence allowing for better formulation of the optimum way to use the modern plating systems in the clinical setting. Biological fracture repair with conventional plates, in terms of a less rigid construct to enhance fracture healing, is becoming increasingly popular. By omitting screws the construct becomes more flexible with a risk of fixation failure. It was the aim of the first paper to investigate in an experimental model the construct strength of different conventional plate lengths and number / position of the screws, and if an oblique screw at the plate end could increase the fixation strength. Our data suggest that the plate length is the most important factor in withstanding forces in cantilever bending. Longer plates with an equal number of screws require greater peak loads to failure than short plates with more screws. Furthermore, an oblique screw at the plate end produces an increased strength of fixation in all different test setups. However, the difference is more significant in shorter plates and in constructs with no screw omission adjacent to the fracture site. ... Following cyclic loading, however, locking plates can better retain fracture reduction compared to compression plates. On the other hand, under torsional load the compression plate appears to be biomechanical superior to the locking system. In supracondylar comminuted femur fractures, combining the two principles results in less plastic deformation, and a higher load to failure compared to their single application. The last two papers examine the behaviour of locking plates in osteopenic bone. In cadaveric intra-articular calcaneal fractures, the locking plate showed a significantly lower irreversible deformation during cyclic loading and a significantly higher load to failure. In dorsal and volar fixed angle distal radius constructs in a cadaveric model, all constructs showed adequate stability with minimal deformation on fatigue testing under physiological conditions in good bone quality. In osteoporotic bone, however, dorsal fixed angle constructs are stiffer and stronger than volar constructs. The addition of a styloid plate to a volar plate does not significantly improve stability.
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朱月華 and Yuet-wah Chu. "The use of a Chinese medicinal formula (Chuan-Duan-Bu-Gu-San) on experimental fracture healing in a mouse model." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31227302.

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Vinnars, Bertil. "Scaphoid fractures : Studies on diagnosis and treatment." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8845.

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Cueva, Luis Orlando Baselly. "Características da membrana induzida pela técnica de Masquelet em defeito ósseo do rádio em galinhas." Botucatu, 2019. http://hdl.handle.net/11449/182706.

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Orientador: Sheila Canevese Rahal
Resumo: O presente estudo visou avaliar temporalmente a formação e a qualidade da membrana induzida de Masquelet, tendo por modelo uma falha óssea segmentar induzida no rádio de galinhas. Foram utilizadas 16 galinhas saudáveis, com um ano de idade e massa corpórea média de 1,45 kg. Sob anestesia geral inalatória, foi induzido defeito segmentar de 1,5 cm no rádio esquerdo, o qual foi preenchido com cimento ósseo na fase pastosa. Os defeitos foram avaliados por meio de exames radiográficos e ultrassonográficos, imediatamente após o procedimento cirúrgico e aos sete, 15, 21 e 30 dias de pós-operatório. Para a avaliação histológica das membranas induzidas, uma ave foi submetida à eutanásia aos sete dias (estudo piloto) de pós-operatório e cinco aves aos 15, 21 e 30 dias de pós-operatório. No exame radiográfico do pós-operatório imediato foi possível verificar a presença do cimento ocupando a falha óssea segmentar, como uma massa radiopaca, com variações de intensidade. Com 30 dias de pós-operatório já foi evidente a presença de nova formação óssea partindo de ambas as extremidades fraturadas. Pelo exame ultrassonográfico, as membranas mostraram a maior formação de vascularização aos 30 dias de pós-operatório. Pela avaliação histológica a membrana aos sete e 15 dias de pós-operatório tinha três zonas distintas, porém aos 15 dias havia presença de neovascularização, fibras colágenas organizadas e diminuição de células inflamatórias. Aos 21 dias após a cirurgia houve uma perda de delimitaçã... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: This study aimed to evaluate the formation and quality of the induced membrane in Masquelet's technique, using a segmental bone defect induced in the chicken’s radius. Sixteen healthy domestic chickens, 1 year old and weighing 1.45 kg were used. Under general anesthesia, a 1.5-cm segmental bone defect was induced in the left radius, which was filled with bone cement during its pasty polymerization phase. The bone defects were evaluated by plain X-rays and ultrasounds, immediately after surgery and at seven, 15, 21 and 30 days postoperatively. One bird was euthanized at 7 days after surgery (pilot study), and five birds were euthanized at 15, 21 and 30 days postoperatively for histological evaluation of the induced membranes. Immediate postoperative radiographic examination showed the presence of cement that occupied the segmental bone defect, as a radiopaque mass, with intensity variations. Thirty days after surgery the presence of new bone formation at the fractured extremities was evident. Ultrasound evaluation showed that the induced-membrane had the highest rate of vascularization at 30 days post-surgery. Histologically, the induced-membrane had three distinct zones at 7 and at 15 days postoperatively, but day 15 had neovascularization, organized collagen fibers and reduced of inflammatory cells. At 21 days after surgery, the zones were less defined and there was cartilage and bone metaplastic areas. At 30 days postoperative diffuse mineralization of the membrane was obse... (Complete abstract click electronic access below)
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Roberts, C. A. "Trauma and its treatment in British antiquity : An osteoarchaeological study of macroscopic and radiological features of long bone fractures from the historic period with a comparative study of clinical radiographs." Thesis, University of Bradford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.384271.

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Books on the topic "Bone fracture treatment"

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Practical fracture treatment. 2nd ed. Edinburgh: Churchill Livingstone, 1989.

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Practical fracture treatment. 3rd ed. Edinburgh: Churchill Livingstone, 1994.

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Esser, Max, FRCS Ed ORTH FRACS., ed. Practical fracture treatment. 4th ed. Edinburgh: Churchill Livingstone, 2003.

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McRae, Ronald. Practical fracture treatment. 2nd ed. Edinburgh: Churchill Livingstone, 1989.

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McRae, Ronald. Practical fracture treatment. 3rd ed. Edinburgh: Churchill Livingstone, 1994.

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Esser, Max, FRCS Ed ORTH FRACS., ed. Practical fracture treatment. 5th ed. Edinburgh: Churchill Livingstone, 2008.

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Charnley, John. The Closed treatment of common fractures. 4th ed. Cambridge: Colt Books in association with The John Charnley Trust, 1999.

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Scherl, Susan A. Surgical management of pediatric long bone fractures. Rosemont, IL: American Academy of Orthopaedic Surgeons, 2009.

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External fixation: Joint deformities and bone fractures. New York, N.Y: International Universities Press, 1987.

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(Matthias), Rapp M., and SpringerLink (Online service), eds. The Double Dynamic Martin Screw (DMS): Adjustable Implant System for Proximal and Distal Femur Fractures. Heidelberg: Steinkopff, 2008.

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Book chapters on the topic "Bone fracture treatment"

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van Griensven, Martijn, and Elizabeth Rosado Balmayor. "Can we accelerate the osteoporotic bone fracture healing response?" In Surgical and Medical Treatment of Osteoporosis, 141–47. Boca Raton : CRC Press, [2020]: CRC Press, 2020. http://dx.doi.org/10.1201/9780429161087-16.

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Hardt, Nicolas, and Harald Essig. "Bone Grafts and Specific Implants in Craniofacial Fracture Treatment." In Craniofacial Trauma, 247–71. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-77210-3_12.

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Moucha, Calin S., and Thomas A. Einhorn. "Bone Morphogenetic Proteins and Other Growth Factors to Enhance Fracture Healing and Treatment of Nonunions." In Bone Regeneration and Repair, 169–94. Totowa, NJ: Humana Press, 2005. http://dx.doi.org/10.1385/1-59259-863-3:169.

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Bucholz, Robert W. "Bone Graft Substitutes in Fracture Management: Basic Science and Clinical Results." In Trends in Research and Treatment of Joint Diseases, 128–34. Tokyo: Springer Japan, 1992. http://dx.doi.org/10.1007/978-4-431-68192-2_16.

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Kiyoshige, Yoshiro. "Bone Cementing in the Treatment of Distal Radius Fracture in Elderly Patients." In Wrist Disorders, 233–36. Tokyo: Springer Japan, 1992. http://dx.doi.org/10.1007/978-4-431-65874-0_28.

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Rai, Anshul. "Fractures of the Mandible." In Oral and Maxillofacial Surgery for the Clinician, 1053–84. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_52.

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AbstractFracture of Mandible is the most common occurrence in comparison to any other bone of the maxillofacial region. Various classifications are put forward which are helpful in diagnosing the mandible fracture. This chapter focuses on the general and clinical examination of the maxillofacial region which helps in clinical diagnosis, different radiographic techniques, various approaches, emergency as well as surgical management and outcome with various modalities of treatment.
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Pattnayak, Subhashree, Devasish Murmu, Manasa Kumar Panda, Rojali Maharana, Kalicharan Mandal, and Nabin Kumar Dhal. "Traditional Herbal Practices of Eastern Ghats, Odisha, India, for Treatment of Bone Fracture." In Advances in Pharmaceutical Biotechnology, 145–54. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-2195-9_12.

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Tamang, Mahendra, Krishan Pal, and Santosh Kumar Rai. "Traditional Use of Plants for the Treatment of Bone Fracture by the Local People of West Sikkim, India." In Medicinal Plants: Biodiversity, Sustainable Utilization and Conservation, 225–36. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-1636-8_12.

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Wilson, Helen, Diana Calcraft, Cai Neville, Susan Lanham-New, and Louise R. Durrant. "Bone Health, Fragility and Fractures." In Perspectives in Nursing Management and Care for Older Adults, 115–34. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-63892-4_9.

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AbstractAchieving and maintaining skeletal health throughout the life trajectory is essential for the prevention of bone diseases such as rickets, osteomalacia and osteoporosis. Rickets and osteomalacia are usually a result of calcium and/or vitamin D deficiency, causing softening of bones and bone pain, and both conditions are treatable with calcium and vitamin D supplementation. Osteoporosis is a multifaceted disease mainly affecting older people, and its pathogenesis (and hence treatment) is more complex. Untreated osteoporosis results in fragility fractures causing morbidity and increased mortality.Nutrition is one of many factors that influence bone mass and risk of bone disease. Developing a nutritional sciences approach is a feasible option for improving bone health.The importance of adequate calcium and vitamin D in ensuring skeletal integrity throughout the life course has a sound evidence base. Poor vitamin D status in population groups of all ages is widespread across many countries (including affluent and non-affluent areas). Public health approaches are required to correct this given the fact that vitamin D is not just required for musculoskeletal health but also for other health outcomes.Dietary protein may be beneficial for bone due to its effect of increasing insulin-like growth-factor-1 (IGF-1). Recent meta-analyses show that dietary protein has a beneficial role to play in bone health at all ages.Other nutritional factors and nutrients (such as potassium, magnesium, vitamin K and acid-base balance) are also likely to have an important role in bone health, though the literature is less clear in terms of the association/relationship and more research is required.
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Balaraman, Kannan. "Frontal and Naso-Orbito-Ethmoid Complex Fractures." In Oral and Maxillofacial Surgery for the Clinician, 1251–66. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_58.

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AbstractNaso-orbito-ethmoid (NOE) injuries constitute about 5% of facial fractures and most of them are as a result of road traffic accidents. Deformities in the region tend to be more cosmetically apparent. Considering the proximity of the area to critical structures like brain and eye, such injuries need to be thoroughly evaluated both clinically and radiologically to understand the extent of the injury as well as initiate emergency management if required prior to constituting a definitive treatment plan. CT scans are the most useful investigation modality. Identification and maintaining the attachment of Medial canthal ligament in appropriate position along with reducing / stabilizing the bony fracture is the key to getting good results in these fractures. Primary management of the deformity produces better results compared to secondary correction.
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Conference papers on the topic "Bone fracture treatment"

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Higgins, Kathryn B., Robert D. Harten, Noshir A. Langrana, and Alberto M. Cuitino. "Biomechanics of Vertebroplasty." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32635.

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Osteoporosis is a skeletal disease characterized by low bone mass and deterioration of bone tissue. It affects 15–20 million women in the United States. Fractures of the vertebrae, wrist and hip are the most common. [1] In the spine, osteoporosis greatly affects the bone mass of the vertebral bodies (VB), the primary structures for transmitting loads in the spine. The VB is comprised of a shell of dense bone surrounding a more porous bony tissue called trabecular bone. Trabecular bone is a lattice-like network of trabeculae in the shape of plates or rods, depending on orientation and one’s age. When the weakened trabecular structure experiences a loss of height, acute back pain, spinal cord compression, and overall loss of mobility can ensue. A single fracture creates a region of high stress in the trabecular network, often leading to more fractures. In almost 20% of the cases one fracture in a VB may result in a secondary fracture within a one year period. [2] Many fractures go unnoticed. The high occurrence, frequent uncertainty of fracture, and gravity of subsequent injury indicate a need to improve the strength of osteoporotic vertebrae before damage can occur. It may be desirable to treat weakened bone prior to fracture. One candidate for prevention that is investigated in this study is vertebroplasty. Currently, the procedure is used to repair fractured VB by injecting acrylic bone cement into the affected level. A parametric finite element (FE) investigation and supporting experimental study was conducted to evaluate the usefulness of vertebroplasty as a preventative treatment.
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"An Informative Machine-Learning Tool for Diagnosis of Osteoporosis using Routine Femoral Neck Radiographs." In InSITE 2019: Informing Science + IT Education Conferences: Jerusalem. Informing Science Institute, 2019. http://dx.doi.org/10.28945/4350.

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Aim/Purpose: The aim of the study was to analyze the structure of the bone tissue by using texture analysis of the bone trabeculae, as visualized in a routine radiograph of the proximal femur . This could provide objective information regarding both the mineral content and the spatial structure of bone tissue. Therefore, machine-learning tools were applied to explore the use of texture analysis for obtaining information on the bone strength. Background: One in three women in the world develops osteoporosis, which weakens the bones, causes atraumatic fractures and lowers the quality of life. The damage to the bones can be minimized by early diagnosis of the disease and preventive treatment, including appropriate nutrition, bone-building exercise and medications. Osteoporosis is currently diagnosed primarily by DEXA (Dual Energy X-ray Absorptiometry), which measures the bone mineral density alone. However, bone strength is determined not only by its mineral density but also by the spatial structure of bone trabeculae. In order to obtain valuable information regarding the bone strength, the mineral content and the spatial structure of the bone tissue should be objectively assessed. Methodology: The study includes 17 radiographs of in-vitro femurs without soft tissue and 44 routine proximal femur radiographs (15 subjects with osteoporotic fractures and 29 without a fracture). The critical force required to fracture the in-vitro femurs was measured and the bones were divided into two groups: 11 solid bones with critical fracture force higher than 4.9kN and 6 fragile bones with critical fracture force lower than 4.9kN. All the radiographs included an aluminum step-wedge for calibrating the gray-levels values (See Figure 3). An algorithm was developed to automatically adjust the gray levels in order to yield equal brightness and contrast. Findings: The algorithm characterized the in-vitro bones with as fragile or solid with an accuracy of 88%. For the radiographs of the patients, the algorithm characterized the bones as osteoporotic or non-osteoporotic with an accuracy of 86%. The most prominent features for estimating the bone strength were the mean gray-level, which is related to bone density, and the smoothness, uniformity and entropy, which are related to the spatial distribution of the bone trabeculae. Impact on Society: Analysis of bone tissue structure, using machine-learning tools will provide a significant information on the bone strength, for the early diagnosis of osteoporosis. The structure analysis can be performed on routine radiographs of the proximal femur, with high accuracy. Future Research: The algorithm for automatic structure analysis of bone tissue as visualized on a routine femoral radiograph should be further trained on a larger dataset of routine radiographs in order to improve the accuracy of assessing the bone strength.
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Graham, A. E., S. q. Xie, W. l. Xu, and S. Mukherjee. "Design of a Parallel Long Bone Fracture Reduction Robot with Planning Treatment Tool." In 2006 IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE, 2006. http://dx.doi.org/10.1109/iros.2006.281885.

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Jiang, Feifei, Jie Chen, David E. Komatsu, and Shuning Li. "Healing Progress of Fractured Bone: A Longitudinal Study." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204787.

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In orthopedics research, assessment of fracture healing progress is vital for evaluating treatment strategies and drug effects. Currently, biomechanical testing represents the ‘gold standard’ for determining the extent of healing, with the parameters of stiffness and strength most often reported. Unfortunately, such testing requires destructive examination of samples, which allows healing to be checked at only one time-point per animal. Thus, evaluation of healing requires large sample sizes to achieve statistical power. In contrast, longitudinal studies of individual animals allows for self-comparison, which is more reliable, and can be used to evaluate bone healing as time elapses. Recently, longitudinal radiographic assessment of bone healing in rats, using parameters such the level of bone mineralization, morphological changes, and distribution of the mineralized bone, has been reported. However, the ability to quantify the biomechanical properties of healing bones based on longitudinal radiographic images provides an tremendous opportunity to increase the value of such studies.
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Daldoul, Cyrine, Nejla El Amri, Sadok Laataoui, Khadija Baccouch, Imtinen Belaid, Hela Zeglaoui, and Elyes Bouajina. "AB0825 IMPACT OF AROMATASE INHIBITOR TREATMENT ON BONE MINERAL DENSITY AND PREVALENT VERTEBRAL FRACTURE." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.8045.

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Altman, Allison R., Beom Kang Huh, Abhishek Chandra, Wei-Ju Tseng, Ling Qin, and X. Sherry Liu. "3D In Vivo Bone Dynamic Imaging of PTH’s Anabolic Action." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14671.

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Aging shifts bone remodeling toward a negative balance between bone formation and resorption, causing bone loss and increased fracture risk. Anti-resorptive agents are commonly used to inhibit bone resorption and stabilize bone mass. While they are effective to prevent further bone loss, there is also a great need for anabolic agents which can reverse bone deterioration and regain lost skeletal integrity. Intermittent parathyroid hormone (PTH) treatment is the only FDA-approved anabolic treatment for osteoporosis, which greatly stimulates bone formation. Combined therapy of anti-resorptive drugs, such as alendronate (ALN), and PTH have been proposed and are expected to further stimulate bone formation. However, studies show conflicting results regarding the effectiveness of combined treatments: some have reported the addition of ALN to impair PTH function [1, 2], while others suggest an improvement over PTH monotherapy [3, 4]. The first objective of this study is to document the immediate changes of individual trabecular structures due to PTH and combined therapy within 12 days using in vivo micro computed tomography (μCT). As PTH is typically prescribed for 1 to 3 years to osteoporotic patients, a treatment of 12 days for rats (approximately equivalent to one year of human life) may be more clinically relevant than long-term treatment studies on rats. The secondary purpose of this study was to gain insight into the mechanism of combined versus PTH treatments through a bone dynamic imaging strategy to track events over an individual remodeling site. We hypothesized that PTH and combined treatments would immediately enhance bone formation on the trabecular surface.
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Assari, Soroush, Kurosh Darvish, and Asif M. Ilyas. "A Biomechanical Study of Scaphoid Headless Screws." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53854.

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Scaphoid fractures are the most common fracture of the carpus [1].Headless screws are favored for internal fixation in the treatment of displaced or unstable fractures, because they are embedded below the articular surface of the bone, reducing tissue irritation and immobilization. Compression plays an important role in fracture stability, maintaining gap reduction and also accelerating the healing of cancellous bone [3]. There are several types of screwsbeing used in practice and it is of clinical interest to know how different they are in generating and maintaining the compression force.
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Samuel, Jitin, Cong-Gui Zhao, Bijay Giri, Debarshi Sinha, and Xiaodu Wang. "Effect of Hydrogen Bonding Ability, Dipole-Dipole Interactions and Viscosity of Extracellular Matrix Fluid on the Bone Mechanical Behavior." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80812.

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Fragility fracture as a mode of pathologic failure in bone is a major healthcare concern and has adverse consequences with respect to morbidity, cost and to a lesser extent mortality. Understanding the structure/composition and functional relationships among the bone constituents is an important step towards prevention/treatment of fragility fractures.
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Wang, Haosen, Zhixiu Hao, Shizhu Wen, and Chao Wan. "Numerical Simulation of the Healing Process in the Tibia Diaphysis Fracture Fixed With External Fixation." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-50693.

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The tibia diaphysis (shaft) fracture is one of the most common long bone fractures, and is usually treated with either the internal or the external fixations. How to choose a proper fixation type is still empirical and controversial. The objective of this study was to investigate whether the lateral external fixation (LEF) is suitable to treat the transverse and oblique tibia diaphysis fracture, from a mechanobiological perspective. The healing processes in the tibia fractures were simulated using the finite element method. The models of both the transverse and oblique (45°) tibia diaphysis fracture fixed with a LEF were built. A mechano-bioregulatory algorithm, which considered both the mechanobiological and biological environments, was developed to simulate the cell and tissue activities inside the callus. The results showed that both fractures healed in a typical secondary osteogenesis process. After 60 days, the regions of external callus and bone marrow were occupied with bone tissue. However, the mechanical stimulus in the inter-cortical region in the oblique fracture model with a less stiff LEF was greater than the stimulus in the transverse fracture model with the same LEF, indicating that the angled fracture was prone to generate greater instability. Moreover, increased osteogenic differentiation threshold only slightly affected the bone formation in the bridging areas, thus, had minor influences on the healing process. In conclusion, the lateral external fixation demonstrated satisfactory capacity in the treatment of the transverse and oblique tibia diaphysis fracture. The oblique fracture was more likely to be affected with a less stiff fixation.
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Askew, Michael J., Gary B. Schneider, Kristina J. Grecco, Jason Hsu, Emily Mugler, and Donald A. Noe. "Effect of Pharmaceutical Bone Growth Stimulation With Novel Anabolic Peptides: Biomechanical and Bone Density Measurements in a Rat Model." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43044.

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Pharmaceutical bone growth stimulation holds promise for prevention and treatment bone disorders, and the enhancement of fracture healing. Bone growth hormones have begun to have limited clinical use, but can illicit adverse side effects. Recent studies have shown that short peptides (less than 15 amino acids) derived from the protein sequence of Vitamin D Binding Protein (DBP), can enhance bone formation (osteogenesis). These peptides may have potential as controllable bone growth stimulators without the adverse side effects and cost of bone growth hormones. Rats, injected every other day for two weeks with DBP-based peptide fragments ranging from 3 to 13 amino acids in length, were euthanized and the tibias and femurs were scanned by peripheral quantitative computerized tomography (pQCT) to determine bone density and cross-sectional geometric properties. The bones were then tested in three-point bending to determine strength and bending modulus. Injection of DBP-based peptides over only a 2-week period resulted in significant (p&lt;0.05) increases in bone density and material properties in the experimental rat bones in comparison to controls injected with saline. The short length of these effective peptides suggests their use not only in systemic injections but also as clinically convenient pills taken orally for pharmaceutically induced bone growth stimulation.
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Reports on the topic "Bone fracture treatment"

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Bush, Joshua. Degradable Bone Graft Substitute for Effective Delivery of Multiple Growth Factors in the Treatment of Nonunion Fractures. Fort Belvoir, VA: Defense Technical Information Center, August 2012. http://dx.doi.org/10.21236/ada567964.

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Mazurek, Michael, Joseph Carney, Carl Carrano, and Dale Chatfield. Antibiotic Impregnated Bone Cement for the Treatment of Osteomelitis and Severe Open Fractures: Expanded Options for Surgeons. Fort Belvoir, VA: Defense Technical Information Center, June 2008. http://dx.doi.org/10.21236/ada586569.

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Bush, Joshua. Degradable Bone Graft Substitute for Effective Delivery of Multiple Growth Factors in the Treatment of Nonunion Fractures. Fort Belvoir, VA: Defense Technical Information Center, October 2011. http://dx.doi.org/10.21236/ada559323.

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