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Books on the topic 'Bone cancer pain'

Author: Grafiati

Published: 13 April 2024

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1

1963-, Davies Andrew, ed. Cancer-related bone pain. Oxford: Oxford University Press, 2007.

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2

Edward, Chow, and Merrick Joav 1950-, eds. Advanced cancer: Pain and quality of life. Hauppauge, N.Y: Nova Science, 2010.

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3

Brennfleck, Shannon Joyce, ed. Pain sourcebook: Basic consumer health information about acute and chronic pain, including nerve pain, bone pain, muscle pain, cancer pain, and disorders characterized by pain, such as arthritis, temporomandibular muscle and joint (tmj) disorder, carpal tunnel syndrome, headaches, heartburn, sciatica, and shingles, and facts about diagnostic tests and treatment options for pain, including over-the-counter and prescription drugs, physical rehabilitation, injection and infusion therapies, implantable technologies, and complementary medicine; along with tips for living with pain, a glossary of related terms, and a directory of additional resources. 3rd ed. Detroit: Omnigraphics, 2008.

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4

Davies, Andrew, ed. Cancer-related Bone Pain. Oxford University Press, 2007. http://dx.doi.org/10.1093/med/9780199215737.001.0001.

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5

Colvin, Lesley A., and Marie Fallon. Cancer-induced bone pain. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0132.

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Bone is the third most common site of metastatic disease, after liver and lung, with approximately 75% of these patients suffering from related pain. Cancer-induced bone pain (CIBP) is a major clinical problem, with limited options for predictable, rapid, and effective treatment for some of the elements without unacceptable adverse effects. Our understanding of how current therapy acts is based mainly on studies in non-cancer pain syndromes, which are likely to be quite different, not only in clinical presentation, but also in terms of pathophysiology. It can be difficult to study the specific neurobiological changes associated with CIBP, although development of laboratory models of isolated bone metastases has allowed more specific study of pain mechanisms in this syndrome. In order to evaluate our current therapies properly and direct the development of new therapies logically, it is important to understand the underlying mechanisms of CIBP. This chapter discusses pain processing and the mechanisms and management of CIBP.

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6

Cancer-Related Bone Pain. Oxford University Press, Incorporated, 2014.

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7

Davies, Andrew. Cancer-Related Bone Pain. Oxford University Press, Incorporated, 2007.

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8

Doré-Savard, Louis, Nicolas Beaudet, and Philippe Sarret. Mechanisms of bone cancer pain. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0037.

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The landmark paper discussed in this chapter focuses on pain arising from malignancy of the bone, which, whether primary or originating from a distant site, is the cause for a majority of cancer pain syndromes. Bone is an innervated organ that can relay nociceptive signals triggered by nerve damage, acidosis, inflammation, and hypoxia. The understanding of the physiopathology of skeletal pain has leaped significantly forwards over the last 15 years. The development of animal models that allowed for the visualization of bone microenvironment modifications by the tumour played an important role in recent advances. One of the most significant discoveries was the contribution of local nerve growth factor (NGF) to nerve remodelling in the bone periosteum presented by Mantyh and colleagues in 2010. NGF remains one the most promising treatment avenues for malignant bone pain, and peripheral innervation has become a therapeutic target in several skeletal pathologies.

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9

Davies, Andrew. Cancer-related Bone Pain (Oxford Pain Management Library S.). Oxford University Press, USA, 2007.

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10

Chow, Edward. Advanced Cancer: Pain and Quality of Life. Nova Science Publishers, Incorporated, 2021.

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11

Healey, John H., and David McKeown. Orthopaedic surgery in the palliation of cancer. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0125.

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Metastatic spread of cancer to bone is frequent and causes pain, disability, and functional limitation. New understanding of the homing method of cancer cells to bone and the mechanism of cancer production of pain raise possible new treatment strategies. Non-surgical treatments such as chemotherapy and hormone therapy are effective in early disease. Bisphosphonates and inhibition of osteoprotegerin prevent progression of bone lesions and avoid pain, radiation, and surgery. Radiotherapy arrests disease and relieves pain in many cases. Surgery is needed when the bone is weak or fractured. It effectively relieves pain and preserves function. It usually requires replacing or bypassing the deficient bone with site-specific reconstructive surgery. Surgery should be selected based on projections of patient survival. New tools to make these projections have been validated and are now available. New targeted drug therapies appear to be changing metastatic bone disease into a more chronic condition. This will alter the management of local disease in many histological subtypes of metastatic cancers.

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12

Chazminare, Allex Sun. Bone Marrow Cancer Symptoms: Fatigue, Weight Loss, Decreased Appetite, Pallor, Bone Pain, Decreased Urinary Output, Fever, Bruising, Bleeding Gums, Tingling or Numbness. Independently Published, 2021.

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13

Merrick, Joav, Edward Chow, Nemica Thavarajah, Natalie Pulenzas, and Breanne Lechner. Advanced Cancer: Managing Symptoms and Quality of Life. Nova Science Publishers, Incorporated, 2013.

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14

Malik, Tariq M. Back Pain: It’s Not Always Arthritis. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0029.

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Back pain is prevalent in adults, and most often its cause is nonspecific and benign. Imaging and interventions are not always helpful and they are generally expensive and low yield. However, in about 10% or fewer cases, a specific etiology is found. A patient history, physical examination, and testing are the methods for finding the cause. Back pain from malignancy must also be considered. Prolonged survival from better chemotherapy has increased the incidence of metastases to bone, especially the spine. Common sources of spinal metastases are cancers of the prostate, kidneys, thyroid, breast, and lungs. The primary treatment is to address the malignancy. Pain from spinal tumors can be treated with chemotherapy, radiotherapy, radiofrequency, or vertebral augmentation therapy. The chapter reviews the epidemiology of spinal cancer pain, evaluation of malignant spinal pain, and what the interventional pain physician can offer patients to alleviate their pain.

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15

Scott-Brown, Martin. Symptom control in cancer. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0329.

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Treatment in cancer is aimed at improving survival (curing where possible) and/or improving symptoms. Symptoms may be caused by the cancer itself (primary tumour, metastases, or paraneoplastic phenomenon) or by the treatments patients undergo to treat the cancer (surgery, radiotherapy, chemotherapy, hormone therapy, and biological therapy). Therefore, symptom control is one of the key roles of oncologists as they treat cancer patients. The most important part of symptom control in cancer patients is to elucidate the underlying cause of the symptom. Symptom control is most effective when the underlying cause is targeted; for example, shoulder pain may be treated most effectively by local radiotherapy if it is due to a bone metastasis in the humeral head, by dexamethasone if it is referred pain due to diaphragmatic irritation from hepatomegaly, and by amitriptyline or gabapentin if it is neuropathic pain due to cervical nerve root irritation. Covering all symptom control in cancer patients is beyond the remit of this chapter; however, it will cover the control of pain and nausea and vomiting, as these are very common symptoms in cancer patients.

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16

Castle, David J., Peter F. Buckley, and Fiona P. Gaughran. Other physical health problems in people with schizophrenia. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198811688.003.0004.

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While cardiovascular risk remains the most important factor in early death among people with schizophrenia, a host of other physical health maladies are also found in excess in this group of individuals. These include pulmonary problems, poor bone health with associated risk of fractures, sexual health problems, infectious diseases, and poor oral health. Certain cancers are seen in excess in people with schizophrenia, but what is perhaps more of a shameful indictment of our health systems is that if they develop cancer, they are less likely to be effectively treated than people without a mental illness. Intriguingly, there is some evidence of higher pain tolerance among people with schizophrenia, as well as remarkably low rates of degenerative musculoskeletal conditions.

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17

Cascarini, Luke, Clare Schilling, Ben Gurney, and Peter Brennan. In the clinic. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198767817.003.0005.

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This chapter discusses oral and maxillofacial surgery in the clinic, including, Mandible fractures, Orbital floor fractures, Zygoma fractures, Maxillary fractures, Nose, naso-ethmoidal, and frontal bone fractures, Face and scalp soft tissue injuries, Dento-alveolar: assessment for extractions, Dento-alveolar: impacted teeth, Dento-alveolar: jaw pathologies, Temporomandibular joint problems, Oral and facial pain, Management of oral lesions, Management of neck lumps, Skin tumours, Work-up for major head and neck oncoplastic surgery, Reviewing head and neck cancer patients, Salivary gland diseases, Orthognathic patients, and Miscellaneous conditions in the clinic

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18

Nouri, Kent H., and Billy K. Huh. Superior Hypogastric Block and Neurolysis: Fluoroscopy, Ultrasound, Computed Tomography. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199908004.003.0035.

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The superior hypogastric block (SHB) is an effective treatment for chronic or cancer-related pelvic pain. The CT-guided block offers the advantage of being able to visualize the target structure, soft tissue, disc, and bony structures to minimize complications. But CT has its own limitations such as being unable to visualize the needle at off angle, higher level of exposure to ionizing radiation, and longer procedure time compared to the fluoroscopy-guided procedure. Several variations to CT-guided techniques have been published. Each has its own advantages and disadvantages, but depending on the anatomical variations in spinal structure, any one of the techniques may be used. Fluoroscopy is used in the majority of superior hypogastric blocks because of the ease of use, availability, and quicker procedure times. The anterior approach to SHB using ultrasound guidance is useful technique in relieving pelvic pain in gynecological malignancies.

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19

Manuel, Solmaz P., Christine L. Mai, and Robert Brustowicz. Orthopedic Surgery. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199398348.003.0018.

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Anesthesia for pediatric orthopedic and spinal surgery presents multiple challenges for the anesthesiologist. Children often present with comorbidities and concomitant diseases that affect the respiratory and cardiovascular functions. Significant blood loss and prolonged operating times can pose significant risks. Airway management in a child with a syndrome can be both difficult and challenging. Orthopedic tumor surgery may be complicated by chemotherapy treatment, anesthetics can be affected by drug interactions, and postoperative pain management can be complex. In this chapter, we review common coexisting diseases in pediatric patients undergoing orthopedic surgeries. These diseases include syndromes such as Down syndrome, Marfan syndrome, and Klippel-Feil syndrome; muscular dystrophies such as Duchenne muscular dystrophy; and bony cancers such as osteosarcoma.

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