Dissertations / Theses on the topic 'Blood glucose'
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Rahaghi, Farbod N. "Human blood glucose dynamics." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2007. http://wwwlib.umi.com/cr/ucsd/fullcit?p3259621.
Full textTitle from first page of PDF file (viewed June 21, 2007). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references (p. 269-276).
Eagles, O. D. "Non-invasive blood glucose monitoring." Thesis, Swansea University, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.636758.
Full textKumari, N. "Blood glucose levels and wellbeing." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.374804.
Full textParekh, Bhavin. "Volatile biomarkers of blood glucose." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609459.
Full textOwren, Marit. "Automatic Blood Glucose Control in Diabetes." Thesis, Norwegian University of Science and Technology, Department of Engineering Cybernetics, 2009. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-8974.
Full textIn this thesis, a closed-loop control algorithm for regulating the blood glucose concentration in type 1 diabetic patients is developed. Two control criteria are imposed on the system, namely: -Avoidance of hypoglycemia. (blood glucose concentrations should always be above $3 frac{mmol}{L}$) -Reduction in the average blood glucose concentration compared to what is achieved with manual control. (average blood glucose concentrations should preferably be less than $7.0 frac{mmol}{L}$). The developed control algorithm manages to fulfill both these control criteria. Hypoglycemia is avoided, and average blood glucose concentrations is reduced by $20%$ and $22%$ to a level of $7.0 frac{mmol}{L}$ and $6.9 frac{mmol}{L}$ in the two test subjects. However, further experiments should be carried out to test the robustness of the control algorithm, and a thorough investigation of safety issues for the user needs to performed. As a basis for the implementation of closed-loop blood glucose control, data from three diabetic patients is used to identify the parameters of a proposed mathematical model of the human insulin-glucose regulatory system. The identification process reveals that there is large variations between individual patient's parameter values, and the difference in insulin sensitivity is found to be specially high, both between and within patients.
Abel, Evan Dale. "Insulin and blood pressure." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.257939.
Full textKultala, Henrik, and Simon Persson. "Blood-glucose prediction : Comparing insulin treatment methods." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-280324.
Full textTyp 1 diabetes kräver insjuknade att injicera artificiellt framställt insulin för att kontrollera blocksockernivån. Processen kan till viss del automatiseras med hjälp av insulinpumpar och kontinuerliga glukosmätningssytem, vilka möjliggör automatiska insulininjektioner och automatiska blodsockermätningar. För att kunna injicera rätt mängd insulin behöver framtida glukosvärden förutspås, och noggrannheten i uppskattningen av glukosvärdena avgör hur autonomt ett sådant system kan agera. I denna rapport undersöks prestandan för en maskininlärningsmodell när data från olika insulinbehandlingsmetoder används. De två behandlingsmetoderna som jämförs är ett “closed-loop” system och ett traditionellt insulinpumpsystem. Genom att träna ett “convolutional recurrent neural network” separat på de olika datamängderna jämfördes de resulterande modellerna inom fyra olika prestandamått; “root-mean-square error”, “mean average relative difference”, “Matthews correlation coefficient” för hypoglykemi och “Matthews correlation coefficient” för hyperglykemi. Resultaten visade en viss indikation på att modellerna som hade tränats på data från “closed-loop” systemet var bättre, men skillnaderna var för små för att vara statistiskt signifikanta. För att få mer avgörande resultat skulle det behövas en studie med fler kliniska patienter.
Talebi, Fard Sahba. "Glucose monitoring measuring blood glucose using vertical cavity surface emitting lasers (VCSELs)." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/1509.
Full textEkram, Fatemeh. "Blood glucose regulation in type II diabetic patients." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/57070.
Full textApplied Science, Faculty of
Chemical and Biological Engineering, Department of
Graduate
Araujo, Cespedes Fabiola. "RF Sensing System for Continuous Blood Glucose Monitoring." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6998.
Full textBoorsma, JoAnn, and University of Lethbridge Faculty of Arts and Science. "Hot flashes, blood glucose and diabetic postmenopausal women." Thesis, Lethbridge, Alta. : University of Lethbridge, School of Health Sciences, 2008, 2008. http://hdl.handle.net/10133/652.
Full textix, 109 leaves ; 29 cm.
Owens, D. S. "The relationship between blood glucose and psychological functioning." Thesis, Swansea University, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.638385.
Full textFernando, Warnakulasuriya Chandima. "Blood Glucose Prediction Models for Personalized Diabetes Management." Thesis, North Dakota State University, 2018. https://hdl.handle.net/10365/28179.
Full textPears, John Stuart. "Glucose-6-phosphatase : its structure, function and regulation in relation to blood glucose homeostasis." Thesis, University of Edinburgh, 1993. http://hdl.handle.net/1842/20100.
Full textRussell, Morgan D. "The Effect of Caffeine Gum Administration on Blood Glucose and Blood Lactate during Cycling to Exhaustion." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1217006383.
Full textSte, Marie Linda. "Role of norepinephrine in glucose homeostasis /." Thesis, Connect to this title online; UW restricted, 2003. http://hdl.handle.net/1773/9258.
Full textPeterson, Jyme Lynn Peterson. "Psyllium lowers blood glucose and insulin concentrations in horses." Thesis, Montana State University, 2010. http://etd.lib.montana.edu/etd/2010/peterson/PetersonJ0510.pdf.
Full textLee, Chi-yeung. "Estimation of blood glucose variations using noninvasive metabolic measurements." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/hkuto/record/B39330680.
Full textLee, Chi-yeung, and 李子洋. "Estimation of blood glucose variations using noninvasive metabolic measurements." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39330680.
Full textCiréfice, Morgane. "Engineering of a monospecific protease for blood glucose diagnostics." Strasbourg, 2009. https://publication-theses.unistra.fr/public/theses_doctorat/2009/CIREFICE_Morgane_2009.pdf.
Full textThe blood glucose determination via the rate of glycated hemoglobin (HbA1c) is a key-parameter for long-term diabetes care. Roche Diagnostics GmbH committed itself with the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) to develop an international reference standard system for blood sugar control. The glutamyl endopeptidase (GluC) from the V8 strain of Staphylococus aureus (EC 3. 4. 21. 19) is used for the HbA1c digestion. The aim of this phD project is to increase the hydrolysis speed of the GluC by directed evolution by keeping its original enzymatic characteristics (specificity and stability) in the standard conditions of the functional hemoglobin test. A variant with the improved enzymatic features was isolated and identified after the construction and the multiparameter screening of libraries of thousands of mutants. This variant of the glutamyl endopeptidase was expressed in B. Subtilis by extracellular secretion, and then purified by Ni-NTA affinity chromatography. It was then characterized after activation by autoproteolysis. The specific activity of the variant is three times enhanced and the affinity constant (Km) is 3 times improved in a Tris-HCl buffer at pH 7. 8, compared to the wild type glutamyl endopeptidase. The specific activity is four times better in ammonium acetate buffer at pH 4. 3 with the hemoglobin hexapeptide as substrate. It is also more stable at 50°C. However, although the variant is more active with synthetic substrate, it is less competitive than the wild type V8-Glutamyl endopeptidase regarding the activity, affinity and cutting specificity for the hexapeptide of the whole hemoglobin. Experiments are still discussed to optimize the conditions of the HbA1c test
Spyer, Ghislaine. "The role of glucokinase in glucose sensing in man." Thesis, University of Exeter, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248314.
Full textLaurell, Thomas. "Microdialysis and continuous glucose monitoring towards wafer integration /." Lund : Lund Institute of Technology, Dept. of Electrical Measurements, 1995. http://catalog.hathitrust.org/api/volumes/oclc/37932770.html.
Full textZachrisson, Ingmar. "Diabetes and puberty : studies on hormonal factors of importance to the blood glucose control /." Stockholm, 2000. http://diss.kib.ki.se/2000/91-628-4455-5/.
Full textFelton, C. V. "Design of glucose analysis procedures suitable for incorporation into a microprocessor controlled regulator of blood glucose in the newborn." Thesis, University of Wolverhampton, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377551.
Full textOlsson, Joanna. "Swedish Elite Swimmers Blood Glucose Levels During Recovery : A Descriptive Study Using Continuous Glucose Monitoring Systems." Thesis, Gymnastik- och idrottshögskolan, GIH, Institutionen för idrotts- och hälsovetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:gih:diva-4770.
Full textEskaf, Khaled Ahmed. "Blood glucose level prediction for diabetic patients using intelligent techniques." Thesis, University of Salford, 2011. http://usir.salford.ac.uk/26665/.
Full textHawdon, Jane Melinda. "Metabolic adaptation and disordered blood glucose homeostasis in the neonate." Thesis, University of Newcastle Upon Tyne, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240735.
Full textWalmsley, A. R. "The kinetics of glucose transport in human red blood cells." Thesis, University of Manchester, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.377727.
Full textPatchava, Krishna Chaitanya. "Sensing and signal processing for non-invasive blood glucose monitoring." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/19823/.
Full textShulga, Yelena A. "Model-based calibration of a non-invasive blood glucose monitor." Digital WPI, 2006. https://digitalcommons.wpi.edu/etd-theses/58.
Full textKong, Chae-Ryon. "Clinical feasibility of Raman spectroscopy for quantitative blood glucose measurement." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/66013.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 167-175).
Diabetes mellitus is a leading cause of morbidity and mortality worldwide, and close monitoring of blood glucose levels is crucial for its diagnosis and management. Currently, blood glucose monitoring is done by blood withdrawal or through invasive access to the interstitial fluid. While Raman spectroscopy has been studied as a possible non-invasive optical technique for measuring blood glucose, it still faces several practical difficulties. These include tissue turbidity and autofluorescence, the lag between blood and interstitial fluid glucose concentrations, and the inherently weak intensity of aqueous glucose Raman signatures with respect to those of the interfering tissue. This thesis investigates the feasibility of using Raman spectroscopy as a non-invasive technique for blood glucose monitoring, and studies different strategies to overcome the barriers to clinical application. In particular, the study proposes a dynamic concentration correction scheme to correct for the calibration errors arising from the lag between glucose concentrations in the bloodstream and the interstitial fluid. In addition, Monte Carlo simulations were employed to study the differences in the distribution of Raman scattered photons along the depth of the tissue between backscattered and transmission mode Raman spectroscopy. Finally, a portable clinical Raman spectroscopy unit was developed utilizing a non-imaging optical element called a compound hyperbolic concentrator (CHC). The CHC coupled with a matching focusing lens efficiently collects and collimates Raman light from highly scattering tissues, while maintaining much smaller physical dimensions than a compound parabolic concentrator. Using the clinical instrument, skin Raman spectra were collected from healthy human subjects undergoing oral glucose tolerance tests, while the corresponding reference blood glucose concentrations were measured simultaneously with a conventional finger-stick glucose meter. From these datasets, linear and non-linear multivariate calibration techniques were used to relate the Raman spectral intensities to the glucose concentrations. The calibrated algorithms were then tested to demonstrate clinical accuracy as required by the Food and Drug Administration and the International Organization for Standardization. Despite the remaining challenges, the promising results obtained in this study provide important insights required in the clinical translation of Raman spectroscopy for non-invasive blood glucose monitoring.
by Chae-Ryon Kong.
Ph.D.
Strahm, Anna Marie. "Psychological Stress, Stress Reactivity and Blood Glucose Metabolization During Pregnancy." Diss., North Dakota State University, 2020. https://hdl.handle.net/10365/31859.
Full textDlugasch, Lucie. "The Experiences of Self-Monitoring of Blood Glucose Usage of Adults with Type 2 Diabetes Mellitus who are not using Insulin." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/262.
Full textRees, Philip. "The role of insulin in blood glucose abnormalities in canine babesiosis." Diss., University of Pretoria, 2010. http://hdl.handle.net/2263/24887.
Full textDissertation (MMedVet)--University of Pretoria, 2010.
Companion Animal Clinical Studies
unrestricted
Lammertyn, Leandi. "Blood glucose and nocturnal blood pressure in African and Caucasian men : the SABPA study / L. Lammertyn." Thesis, North-West University, 2010. http://hdl.handle.net/10394/4649.
Full textThesis (M.Sc. (Physiology))--North-West University, Potchefstroom Campus, 2011.
Vezouviou, Evangelia. "A near infrared holographic glucose sensor for diabetes management." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648782.
Full textLau, Chuk-ping, and 劉祝屏. "The effect of antipsychotics on blood glucose level/lipid level of patients with mental illness." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206545.
Full textpublished_or_final_version
Psychological Medicine
Master
Master of Psychological Medicine
Mbu, Desiree Lem. "Expression of circulating Microrna’s (Mirnas) in blood of mixed ancestry subjects with glucose intolerance." Thesis, Cape Peninsula University of Technology, 2018. http://hdl.handle.net/20.500.11838/2816.
Full textBackground: Early detection of individuals who are at risk of developing Glucose Intolerance would decrease the morbidity and mortality associated with this disease. MicroRNA is one of the most widely studied biomolecules involved in epigenetic mechanisms, hence it offers unique opportunities in this regard. Circulating microRNAs are associated with disease pathogenesis during the asymptomatic stage of disease. This has therefore attracted a lot of attention as a potential biomarker for identifying individuals who have an increased risk of developing Glucose Intolerance. The identification of high risk biomarkers for Glucose Intolerance will go a long way to eliminate the possible complications that arise due to late diagnosis and treatment of Glucose Intolerance. This could ultimately lead to better ways to prevent, manage and control the Glucose Intolerance epidemic that is rampant worldwide. The aim of the study is to investigate expression of circulating microRNA’s in blood of mixed ancestry subjects with glucose intolerance. Methods: A quantitative cross-sectional study design involving 36 individuals [who were age, gender and BMI (Body Mass Index) matched] from a total population of 1989 participants of mixed ancestry descent, residing in Bellville South, South Africa was used. Participants were classified as controls (normoglycemic), pre-diabetic (preDM) and diabetic (DM) (screen detected diabetic) according to WHO criteria of 1998. MicroRNAs were extracted from serum using the Qiagen miRNeasy Serum/Plasma Kit (ThermoFisher). The purified micro RNAs were reverse-transcribed to cDNA (complementary deoxyribonucleic acid) using the Qiagen RT2 First Strand Kit. Then, using Qiagen miScript SYBR Green PCR kit and miScript miRNA PCR arrays (ThermoFisher), the real time polymerase chain reaction was done to determine the expression profile the circulating micro RNAs present in the serum of the participants. Results: The 36 participants were evenly divided into 3 groups of 12 participants each as mentioned earlier. There were significant differences between groups in the waist (cm) (p=0.0415) and waist/hip ratio (p=0.0011) with highest values in the DM group and lowest in the normal group. Clinical parameters varied significantly according to glycemic status. As expected, the FBG (mmol/L) (p<0.0001), 2 HRs Post Glucose (mmol/L) (p<0.0001), HbA1c (%) (p=0.0009), Fasting Insulin (mIU/L) (p=0.0039), were all highest in the DM and lowest in the control group. In contrast, the 2 HRs Post Insulin (mIU/L) (p = 0.0027) was highest in the preDM group and lowest in the normal group, while the Glucose/Insulin ratio (p=0.0477) was highest in the normal group and lowest in the preDM group. Triglycerides (mmol/L) (p=0.0043) and Total Chol (mmol/L) (p=0.0429) were significantly increased through the three groups, with highest values in the DM group and lowest in the normal group. Furthermore, 12 of the 84 miRNAs studied were expressed through all the 3 groups and they exhibited both inverse and positive correlations between the clinical parameters, especially the glucose parameters (Fasting blood glucose, 2 hours post glucose, Fasting blood insulin, 2 hours post insulin and Glycated Hemoglobin).
Rudenski, A. "Development of a model of insulin/glucose regulation to assist elucidation of the pathophysiology of type 2 diabetes mellitus." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.382881.
Full textZhao, Z. (Zuomin). "Pulsed photoacoustic techniques and glucose determination in human blood and tissue." Doctoral thesis, University of Oulu, 2002. http://urn.fi/urn:isbn:9514266900.
Full textHeath, David. "Non-invasive blood glucose monitoring by novel investigation with electromagnetic radiation." Thesis, University of Strathclyde, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549386.
Full textYilmaz, Tuba. "Wearable RF sensors for non-invasive detection of blood-glucose levels." Thesis, Queen Mary, University of London, 2013. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8765.
Full textBarman, Ishan. "Unraveling the puzzles of spectroscopy-based non-invasive blood glucose detection." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/67575.
Full textCataloged from PDF version of thesis.
Includes bibliographical references.
Disorders of glucose homeostasis, including types 1 and 2 diabetes, represent a leading cause of morbidity and mortality worldwide. Diagnosis and therapeutic monitoring of diabetes requires direct measurement of blood glucose. Regardless of the clinical test performed, however, withdrawal of blood is currently required for measurement of blood glucose levels. Non-invasive measurement of blood glucose levels is highly desired, given the large number of diabetics who must undergo glucose testing several times each day. In this context, near-infrared (NIR) Raman spectroscopy has shown substantial promise by providing successful predictions of glucose at physiologically relevant concentrations in vitro and even in individual human volunteers at single sittings. Nevertheless, prospective application of a spectroscopic calibration model - over a larger population or over several sittings - has proven to be challenging. This thesis investigates the optical and physiological challenges that impede calibration transfer by introducing non-analyte specific variances. Specifically, we present major advances in four research directions. First, the effects of sample-to-sample turbidity induced variations in quantitative spectroscopy are studied. To account for these variations, a novel method, based on the photon migration theory, is proposed. We demonstrate that the proposed method can extract intrinsic line shapes and intensity information from Raman spectra acquired in a turbid medium thereby improving quantitative predictions significantly. Second, we quantify the sensitivity of Raman calibration models to endogenous fluorescence and its temporal quenching. Application of shifted subtracted Raman spectroscopy is proposed to reduce the possibility of spurious models developed on the basis of chance correlation between the concentration dataset and quenched fluorescence levels. Third, we solve the problem of physiological lag between blood and interstitial fluid glucose levels, which creates inconsistencies in calibration, where blood glucose measurements are used as reference but the acquired spectra are indicative of ISF glucose levels. To overcome this problem, we introduce a mass transfer-based concentration correction scheme and demonstrate its effectiveness in clinical studies. Finally, we propose a new design for fabricating a handheld Raman glucose monitor by employing excitation and detection of wavelengths selected on the basis of their spectral information content. Based on the advances in instrumentation and methodology outlined in this thesis, we anticipate that our current clinical studies will establish the viability of Raman spectroscopy for non-invasive blood glucose detection.
by Ishan Barman.
Ph.D.
Christison, Graham B. "The determination of blood glucose concentrations by infrared laser photoacoustic spectroscopy." Thesis, Heriot-Watt University, 1992. http://hdl.handle.net/10399/1982.
Full textWalters, Robert P. "Frontal Regulation of Blood Glucose Levels as a Function of Hostility." Thesis, Virginia Tech, 2005. http://hdl.handle.net/10919/35310.
Full textMaster of Science
Kan, Shugen. "Novel control system for blood glucose using a model predictive method." Kyoto University, 2003. http://hdl.handle.net/2433/148493.
Full textNishida, Danielle. "A Wearable 1.6GHz Non-Invasive Midfield Wave-Based Blood Glucose Sensor." DigitalCommons@CalPoly, 2015. https://digitalcommons.calpoly.edu/theses/1367.
Full textLucca, Julie Ann. "ASSOCIATIONS BETWEEN ALCOHOL CONSUMPTION AND FASTING BLOOD GLUCOSE IN YOUNG ADULTS." DigitalCommons@CalPoly, 2013. https://digitalcommons.calpoly.edu/theses/1057.
Full textYu, Fei. "Sonophoretic effects on transdermal glucose extraction with reverse iontophoresis /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?MECH%202007%20YU.
Full textMcClung, Melanie J. Jean B. Randall. "Calibration methodology for a microwave non-invasive glucose sensor." Waco, Tex. : Baylor University, 2008. http://hdl.handle.net/2104/5164.
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