Relevant bibliographies by topics / Blood-brain-barrier-on-a-chip

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic 'Blood-brain-barrier-on-a-chip'

Author: Grafiati
Published: 10 December 2022
Last updated: 31 July 2025

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Journal articles on the topic "Blood-brain-barrier-on-a-chip"

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Zhou, Shutong. "Blood-brain barrier on-a-chip and its application." Theoretical and Natural Science 8, no. 1 (2023): 290–95. http://dx.doi.org/10.54254/2753-8818/8/20240433.

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In the past five years, the organ-on-a-chip technology developed quickly and provided a novel platform for in vitro modelling and experimental testing. Blood-brain barrier (BBB) is an important barrier separating the brain from the rest of the body, thereby protecting the brain from toxins. It is important to study the BBB in terms of its permeability to various molecules, not only identifying potential toxins that might harm the brain, but also to design administration routes for drugs targeting the central nervous system (CNS). This review will summarize various recent designs of the BBB chi
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Deosarkar, Sudhir P., Balabhaskar Prabhakarpandian, Bin Wang, Joel B. Sheffield, Barbara Krynska, and Mohammad F. Kiani. "A Novel Dynamic Neonatal Blood-Brain Barrier on a Chip." PLOS ONE 10, no. 11 (2015): e0142725. http://dx.doi.org/10.1371/journal.pone.0142725.

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Reshma, S., K. B. Megha, S. Amir, S. Rukhiya, and P. V. Mohanan. "Blood brain barrier-on-a-chip to model neurological diseases." Journal of Drug Delivery Science and Technology 80 (February 2023): 104174. http://dx.doi.org/10.1016/j.jddst.2023.104174.

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Periketi, Praneetha, Karmanjot Kaur, Faisal Naseer Vaid, et al. "Blood brain barrier-on-a-chip permeation to model neurological diseases using microfluidic biosensors." Journal of Knowledge Learning and Science Technology ISSN: 2959-6386 (online) 3, no. 4 (2024): 78–93. http://dx.doi.org/10.60087/jklst.v3.n4.p78.

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The need to understand human body functions, monitor disease progression, and advance in drug development have consistently been major driving forces for medical innovations and advancements. Organ-on-a-Chip technology, particularly Blood-brain-barrier (BBB)-on-chip technology, creates an avenue to closely replicate the brain environment and provides real-time monitoring of cells. Located at the interface between the blood and the brain parenchyma, the blood-brain barrier is crucial for protecting the brain due to its semi-permeable nature, and is responsible for regulating the movement of mol
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Phan, Duc TT, R. Hugh F. Bender, Jillian W. Andrejecsk, et al. "Blood–brain barrier-on-a-chip: Microphysiological systems that capture the complexity of the blood–central nervous system interface." Experimental Biology and Medicine 242, no. 17 (2017): 1669–78. http://dx.doi.org/10.1177/1535370217694100.

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The blood–brain barrier is a dynamic and highly organized structure that strictly regulates the molecules allowed to cross the brain vasculature into the central nervous system. The blood–brain barrier pathology has been associated with a number of central nervous system diseases, including vascular malformations, stroke/vascular dementia, Alzheimer’s disease, multiple sclerosis, and various neurological tumors including glioblastoma multiforme. There is a compelling need for representative models of this critical interface. Current research relies heavily on animal models (mostly mice) or on
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Cui, Baofang, and Seung-Woo Cho. "Blood-brain barrier-on-a-chip for brain disease modeling and drug testing." BMB Reports 55, no. 5 (2022): 213–19. http://dx.doi.org/10.5483/bmbrep.2022.55.5.043.

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Liang, Yan, and Jeong-Yeol Yoon. "In situ sensors for blood-brain barrier (BBB) on a chip." Sensors and Actuators Reports 3 (November 2021): 100031. http://dx.doi.org/10.1016/j.snr.2021.100031.

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Staicu, Cristina Elena, Florin Jipa, Emanuel Axente, Mihai Radu, Beatrice Mihaela Radu, and Felix Sima. "Lab-on-a-Chip Platforms as Tools for Drug Screening in Neuropathologies Associated with Blood–Brain Barrier Alterations." Biomolecules 11, no. 6 (2021): 916. http://dx.doi.org/10.3390/biom11060916.

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Lab-on-a-chip (LOC) and organ-on-a-chip (OOC) devices are highly versatile platforms that enable miniaturization and advanced controlled laboratory functions (i.e., microfluidics, advanced optical or electrical recordings, high-throughput screening). The manufacturing advancements of LOCs/OOCs for biomedical applications and their current limitations are briefly discussed. Multiple studies have exploited the advantages of mimicking organs or tissues on a chip. Among these, we focused our attention on the brain-on-a-chip, blood–brain barrier (BBB)-on-a-chip, and neurovascular unit (NVU)-on-a-ch
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Ahn, Song Ih, and YongTae Kim. "Human Blood–Brain Barrier on a Chip: Featuring Unique Multicellular Cooperation in Pathophysiology." Trends in Biotechnology 39, no. 8 (2021): 749–52. http://dx.doi.org/10.1016/j.tibtech.2021.01.010.

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Thakkar, S., T. Fowke, A. Nicolas, A. L. Nair, M. Pontier, and N. Wevers. "LP-17 Blood-brain barrier on-a-chip to study compound-induced disruption." Toxicology Letters 368 (September 2022): S289—S290. http://dx.doi.org/10.1016/j.toxlet.2022.07.759.

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Dissertations / Theses on the topic "Blood-brain-barrier-on-a-chip"

1

Hajal, Cynthia. "Blood-brain barrier model on a microfluidic chip for the study of tumor cell extravasation." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/118716.

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Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2018.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 50-58).<br>With up to 40% of cancer patients showing metastatic lesions to the brain and a 30% five-year survival rate post-diagnosis, secondary tumors to the brain are a leading cause of cancer-related deaths. Understanding the mechanisms of tumor cell extravasation at the brain is therefore crucial to the development of therapeutic agents targeting this step in cancer metastasis, and to the overall improvement
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Sörensen, Rebecka. "Fabrication and characterization of a blood-brain barrier on-a-chip for electrical characterization of cells." Thesis, Uppsala universitet, Mikrosystemteknik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-369978.

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The blood-brain barrier (BBB) is crucial to maintain brainhomeostasis and prevent toxic substances from entering the brain.Endothelial cells (EC) are essential for the BBB and in this thesistwo different BBB-on-chips were designed for electricalcharacterization of immortalized mouse EC (bEnd3).Indium-Tin-Oxide (ITO) coated glass slides were etched, creating ITOelectrodes with increasing distance between them. The glass slideswere attached to a 3D-printed plastic well with UV-glue. The second prototype was an extension of the first prototype with acopper printed circuit board (PCB) attached to
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Carmo, Marciano Palma do. "A multiplexed organ-on-chip device for the study of the blood-brain barrier." Master's thesis, 2017. http://hdl.handle.net/10451/27713.

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Tese de mestrado integrado em Engenharia Biomédica e Biofísica, apresentada à Universidade de Lisboa, através da Faculdade de Ciências, 2017<br>A barreira hemato-encefálica representa a mais complexa interface entre o sangue e o sistema nervoso central, sendo bastante importante na manutenção da homeostasia do cérebro e em proteger o mesmo de diversas substâncias tóxicas e patogénicas. Contudo, devido à baixa permeabilidade que advém das ligações formadas entre as diversas células endoteliais, esta barreira inibe também a entrada de vários agentes farmacêuticos no cérebro, constituindo assim u
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Book chapters on the topic "Blood-brain-barrier-on-a-chip"

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Lee, Somin, Minhwan Chung, and Noo Li Jeon. "BBB-on-a-Chip: Modeling Functional Human Blood-Brain Barrier by Mimicking 3D Brain Angiogenesis Using Microfluidic Chip." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2289-6_14.

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Chin, Eunice, and Eyleen Goh. "Blood–brain barrier on a chip." In Methods in Cell Biology. Elsevier, 2018. http://dx.doi.org/10.1016/bs.mcb.2018.06.003.

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Liang, Yan, and Jeong-Yeol Yoon. "Sensors for blood brain barrier on a chip." In Vitamins and Hormones. Elsevier, 2024. http://dx.doi.org/10.1016/bs.vh.2024.02.006.

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Jacob, Sharon, Pooja Kaushik, and Suhel Parvez. "Organ-on-a-chip for blood–brain barrier studies." In Human Organs-on-a-Chip Technology. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-13782-2.00014-0.

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You might also be interested in the extended bibliographies on the topic 'Blood-brain-barrier-on-a-chip' for particular source types:
Journal articles
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