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1

Lark, Susan M. Dr. Susan Lark's heavy menstrual flow & anemia self help book: Effective solutions for premenopause, bleeding due to fibroid tumors, hormonal imbalance, endometriosis, endometrial cancer, and low blood count. Berkeley, Calif: Celestial Arts, 1995.

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2

L, Sutton Amy, ed. Blood and circulatory disorders sourcebook: Basic consumer health information about the blood and circulatory system and related disorders, such as anemia and other henoglobin diseases, cancer of the blood and associated bone marrow disorders, clotting and bleeding problems, and conditions that affect the veins, blood vessels, and arteries ... 2nd ed. Detroit, MI: Omnigraphics, 2005.

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3

King, Stephen. El umbral de la noche. Barcelona, Spain: Plaza y Janés, 2001.

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King, Stephen. Night Shift. New York: Knopf Doubleday Publishing Group, 2008.

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5

King, Stephen. Night shift. New York: Anchor Books, 2012.

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6

Danse macabre. Paris: J'ai lu, 2002.

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7

King, Stephen. Night Shift. New York, USA: Anchor Books, 2011.

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8

King, Stephen. Night Shift. London: New English Library, 1986.

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9

King, Stephen. Night shift. Oxford: ISIS Large Print, 1994.

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10

King, Stephen. Night shift. Thorndike, Me: G.K. Hall, 1994.

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11

King, Stephen. Night Shift. New York, USA: New American Library, 1990.

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12

King, Stephen. Night Shift. New York, USA: New American Library, 1986.

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13

King, Stephen. The Shining / 'Salem's Lot / Night Shift / Carrie. 5th ed. New York, USA: Octopus/Heinemann, 1985.

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14

Keshav, Satish, and Alexandra Kent. Rectal bleeding. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0030.

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Rectal bleeding is a common symptom, affecting all age groups, with the highest incidence in the sixth and seventh decades and associated with a higher mortality and morbidity with increasing age. Epidemiological studies have shown rectal bleeding to occur in nearly 1% of hospital admissions. Bleeding stops spontaneously in 80% of cases, although rebleeding occurs in 25%. Common causes are haemorrhoids, diverticular disease, and colorectal cancer or polyps.
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15

Watson, Max, Caroline Lucas, Andrew Hoy, and Jo Wells. Palliative haematological aspects. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199234356.003.0023.

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This chapter on palliative haematological aspects covers anaemia in chronic disorders, blood transfusion, erythropoietin, bleeding and haemorrhage, blood products, bleeding directly related to cancer, haemoptysis, haematemesis, rectal bleeding, haematuria, massive terminal haemorrhage, thromboembolism, deep vein thrombosis (DVT), pulmonary embolism (PE), chronic venous thrombosis, warfarin in patients with cancer, and developing a good relation with haematology colleagues.
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16

McCann, Shaun R. ‘If you prick us, do we not bleed?’. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198717607.003.0008.

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William Shakespeare and many others recognized the connection between trauma and bleeding, and the association of bleeding with childbirth is well established. However, even though the associations are well known, the understanding of the mechanisms underlying blood clotting is relatively recent. Bleeding and clotting continue to be major causes of mortality and morbidity. Cerebrovascular accidents and myocardial infarction, together with cancer, continue to be the main causes of death worldwide. In spite of advances in the understanding of the mechanisms of haemostasis and thrombosis in health and disease, there is still much to learn and a lot more to do to reduce the incidence of bleeding and clotting.
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17

Bowker, Lesley K., James D. Price, Ku Shah, and Sarah C. Smith. Genitourinary medicine. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198738381.003.0019.

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This chapter provides information on the ageing genitourinary system, presentation of benign prostatic hyperplasia, treatment of benign prostatic hyperplasia, presentation of prostatic cancer, prostate-specific antigen, treatment of prostatic cancer, post-menopausal vaginal bleeding, vaginal prolapse, illustrations of prolapse, vulval disorders, sexual function, and HIV in older people.
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18

Webster, Peter, Judith Ritchie, and Veerabhadram Garimella. Colorectal surgery (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198749813.003.0004.

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This chapter seeks to illustrate the interesting and diverse nature of adult colorectal surgery with a number of presentations of both benign and malignant conditions of the colon, rectum, and anus. The cases represent a wide variety of colorectal conditions that most junior surgical trainees will encounter from this specialty electively at outpatient clinic, including constipation, colorectal cancer, fissure-in-ano and fistulas, haemorrhoids, faecal incontinence, and pilonidal disease. Cases also feature emergency presentations commonly encountered on the acute surgical take such as acute diverticulitis, anorectal and pilonidal abscesses, large bowel obstruction, and rectal bleeding. Each case uses a question-based approach to cover relevant information about each complaint, including approaches to investigation and management.haemorrhoids, anal fissure, constipation, cancer, fistula, anorectal sepsis, rectal bleeding, prolapse, ischaemic bowel
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19

Viswanath, Y. K. S., and S. Dresner. Upper gastrointestinal surgery. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198510567.003.0006.

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Bleeding peptic ulcer disease 186Perforated peptic ulcer disease 188Oesophageal rupture and perforation 190Gastro-oesophageal reflux disease 192Para-oesophageal hiatus hernia repair 194Open (Heller's) cardiomyotomy for achalasia 196Open splenectomy 198Weight reduction surgery for morbid obesity 200Radical surgery for gastric cancer ...
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20

Cassidy, Jim, Donald Bissett, Roy A. J. Spence OBE, Miranda Payne, and Gareth Morris-Stiff. Thromboembolic and cardiac emergencies. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199689842.003.0034.

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Describes the incidence and aetiology of excessive clotting and / or bleeding diathesis in cancer. This includes descriptions of disseminated intravascular coagulation, deep vein thrombosis. Outlines investigations and immediate therapy options.Also discusses cardiac events including pericardial effusions. Describes aetiology, pathophysiology, investiagation and therapy of this medical emergency.
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21

Mori, Masanori. Clinical Signs of Impending Death in Cancer Patients (DRAFT). Edited by Nathan A. Gray and Thomas W. LeBlanc. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190658618.003.0039.

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In this prospective, longitudinal, cohort study, the authors systematically characterized the frequency, onset, and diagnostic performance of 62 clinical signs for impending death in 357 advanced cancer patients admitted to two acute palliative care units. “Early signs” (e.g., Palliative Performance Scale <20%, Richmond Agitation Sedation Scale ≤–2) had a high frequency over the last 3 days but low positive predictive ratios (LRs) for impending death within 3 days. In contract, “late signs” (e.g., death rattle, respiration with mandibular movement, peripheral cyanosis) had a low frequency but high specificity and high positive LR. In addition, seven neurological signs (e.g., decreased response to verbal stimuli, drooping of nasolabial fold, grunting of vocal cords) and upper gastrointestinal bleeding had high positive LRs for impending death within 3 days. Upon further validation, these signs may assist clinicians in formulating the diagnosis of impending death and patients and families in preparing ahead.
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22

Jolly, Elaine, Andrew Fry, and Afzal Chaudhry, eds. Gastroenterology and hepatology. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199230457.003.0009.

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Chapter 9 covers the basic science and clinical topics relating to gastroenterology and hepatology which trainees are required to learn as part of their basic training and demonstrate in the MRCP. It covers basic science, gastrointestinal investigation, malabsorption and malnutrition, inflammatory bowel disease, acute upper gastrointestinal haemorrhage, lower gastrointestinal bleeding and related disorders, gastrointestinal infections, gastrointestinal cancer, miscellaneous gastrointestinal problems, normal liver and biliary function, variceal disease, hepatic tumours, acute (fulminant) liver failure, haemochromatosis, Wilson disease (hepatolenticular degeneration), Alpha-1 antitrypsin deficiency, alcohol-induced liver disease, hepatitis, biliary diseases, and non-alcoholic fatty liver disease.
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23

Chan, Kin-Sang, Doris M. W. Tse, and Michael M. K. Sham. Dyspnoea and other respiratory symptoms in palliative care. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0082.

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Dyspnoea is prevalent among palliative care patients with increased severity over time. There are two patterns of dyspnoea-breakthrough dyspnoea and constant dyspnoea-and three separate qualities of dyspnoea-air hunger, work or effort, and tightness. The measurement of dyspnoea includes three domains: sensory-perceptual experience, affective distress, and symptom impact. The management of dyspnoea includes specific disease management, non-pharmacological intervention, pharmacological treatment, and palliative non-invasive ventilation. Cough is prevalent and disturbing in patients with cancer and chronic lung diseases, and is often associated with airway hypersecretion and impaired mucociliary clearance. Management includes specific treatments for underlying non-cancer and cancer-related causes, symptomatic treatment by antitussives, mucoactive agents, and airway clearance techniques for expectoration and reduction in mucus production. Anticholinergics may be indicated for death rattles to facilitate a peaceful death. Haemoptysis occurs in 30-60% of lung cancer patients and initial management of haemoptysis includes airway protection and volume resuscitation. Localization of the site and source of bleeding may determine the choice of treatment. If a life-threatening haemoptysis occurs, sedation should be given as soon as possible. Support should be given to the family, and debriefing provided to team members.
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24

Badgwell, Brian, and Robert S. Krouse. The role of general surgery in the palliative care of patients with cancer. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0124.

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Palliative surgery is defined as surgical intervention in patients with incurable malignancy for symptoms attributable to their cancer. A considerable percentage of consultations at major cancer centres are palliative in nature, resulting in 13-21% of all operations meeting the criteria for palliative surgery. Common symptom groups for evaluation include gastrointestinal obstruction, wound problems/infections, gastrointestinal bleeding, and obstructive jaundice. This chapter outlines the indications, treatment options, and outcomes for these diagnoses and a few less common indications for surgical consultation. Clinical trials are infrequent in this population and there is a paucity of prospective studies with quality of life outcomes measures. Most studies focus on morbidity and mortality as palliative surgery has long been recognized as having increased risk for complications, although recent studies suggest an improvement in this regard. The benefits of palliative surgery should focus on quality of life, symptom control, and symptom prevention. Future studies will be needed to determine the definitions of success and hopefully include patient-reported outcomes assessment.
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25

Owers, Corinne, and Roger Ackroyd. UGI surgery (DRAFT). Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198749813.003.0001.

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The upper gastrointestinal (UGI) tract comprises of the oesophagus, stomach, and duodenum. Although some emergency management of UGI pathology may fall to the remit of the gastroenterologists, this chapter focuses specifically on surgical management of both benign and malignant pathology of these organs. UGI pathology contributes a significant amount to the on-call emergency workload for the general surgeon, as well as the UGI specialist. Subjects covered include the diagnosis and management of common pathologies in the upper gastrointestinal tract that are clinically relevant to those working in general surgery, including: gastro-oesophageal reflux (GORD) and ulcer disease, UGI bleeding, oesophagogastric cancer and bariatric surgery.
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26

Chazminare, Allex Sun. Bone Marrow Cancer Symptoms: Fatigue, Weight Loss, Decreased Appetite, Pallor, Bone Pain, Decreased Urinary Output, Fever, Bruising, Bleeding Gums, Tingling or Numbness. Independently Published, 2021.

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27

Agarwal, Deepti, Ifeyinwa C. Ifeanyi, and Mercy A. Udoji. Intrathecal Drug Delivery Systems. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0030.

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Intrathecal drug delivery (ITDD), while initially intended for terminal oncology patients suffering from cancer pain, is currently widely used for chronic nonmalignant pain states. Before intrathecal drug delivery device (IDDD) implantation, patients with nonmalignant chronic pain must be screened for psychologic, behavioral, and medical etiologies for their pain, in addition to having a documented failure of maximal medical therapy and a successful intrathecal drug trial. Classes of drugs used for intrathecal therapy include opioids, local anesthetics, adrenergic agonists, and NMDA receptor agonists. Drugs currently approved by the FDA for ITDD are morphine, ziconotide, and baclofen. Complications of IDDD implantation are surgical (bleeding, infection, CSF leak, nerve injury), mechanical (due to catheter kink, shear, or disconnection), pharmacologic (overdose, incorrect pump settings, contaminated drugs), or medical (hypogonadotropic hypogonadism).
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28

Lark, Susan M. Dr. Susan Lark's Heavy Menstrual Flow & Anemia Self Help Book: Effective Solutions for Premenopause, Bleeding Due to Fibroid Tumors, Hormonal Imbalance, ... Endometrial Cancer, and Low Blood Count. Celestial Arts, 1996.

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29

Zhu, Nancy Y., and Cynthia Wu. Anaemia, cytopenias, and thrombosis in palliative medicine. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0083.

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Many haematological issues can complicate end-of-life care, including cytopenias and venous thromboembolism (VTE). Anaemia is very common and can significantly impact quality of life; causes include haemorrhage, iron deficiency, nutritional deficiencies, and bone marrow infiltration. Neutropenia from bone marrow failure as a result of disease infiltration or from chemotherapy effects can result in life-threatening infections. Finally, VTE is commonly seen in cancer patients as well as those who require prolonged hospitalization. Symptoms can cause discomfort, mortality is increased, and treatment is associated with major bleeding. Understanding the therapeutic options and their adverse side effects is essential in the management of these complex problems. Despite the presence of effective therapies, it is also important to realize that events such as febrile neutropenia and pulmonary embolism are often seen at the end of life and intervention may not always impact prognosis. The risks of intervention should be weighed against expected benefits when developing appropriate palliative care plans.
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30

Keshav, Satish, and Alexandra Kent. Chronic diarrhoea. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0029.

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Four to five per cent of the Western population suffers from chronic diarrhoea (defined as the passage of >3 stools per day, for >4 weeks), with irritable bowel syndrome (IBS) being the commonest cause in 20–40-year-old patients. It is the commonest reason for referral to secondary care gastroenterology clinics. The list of possible causes of chronic diarrhoea is long but, in the absence of rectal bleeding, loss of weight, or abnormal blood tests, it is unlikely to be due to a serious illness. Laboratory investigations should include serum glucose, electrolytes, renal and liver tests, full blood count, thyroid tests, a coeliac antibody test, C-reactive protein (CRP) measurement to check for systemic inflammation, faecal fat and elastase estimation to check pancreatic exocrine function, faecal microscopy, and culture, although this is insensitive for giardiasis. In young patients with typical features of IBS, these laboratory investigations can be abbreviated to include only glucose, electrolytes, the coeliac antibody test, CRP measurement, and thyroid tests. Endoscopic examination of the large and small intestines is generally only required where there is a suspicion of coeliac disease, chronic giardiasis, microscopic colitis, inflammatory bowel disease, or colorectal cancer. A therapeutic trial of metronidazole for giardiasis is justified where this seems a likely diagnosis.
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31

Schairer, John R., and Steven J. Keteyian. Pathophysiology and causes of pericardial tamponade. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0166.

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Pericardial disease leading to pericardial effusion (PEF) is a common clinical disorder. The most common causes are viral infections, metastatic cancer, renal disease, and bleeding disorders. PEF that accumulates slowly can become quite large before haemodynamic embarrassment occurs, while PEF that accumulates rapidly from trauma or aortic dissection can be small,yet cause haemodynamic embarrassment. As the PEF increases in size, the pressure in the pericardial space increases, leading to a decrease in atrial and ventricular chamber sizes, and limiting filling of the chambers. Ultimately, cardiac output is decreased,resulting in cardiac tamponade. When the limits of the pericardial stretch are reached, the volume in the pericardial sac becomes fixed. Any additional increase of PEF results in decreased cardiac size and any change in chamber size with respiration results in a paradoxical change in size of the other chambers. Tamponade is divided into three phases based on changes in pericardial and arterial pressure and cardiac output. Doppler echocardiography is the cornerstone of the diagnosis, follow-up, and management of PEF. It provides information about the presence, size, and location of the PEF, its impact on right ventricle, right atrium, and inferior vena cava size, and assesses tamponade physiology. Comorbid conditions may modify the signs of tamponade and need to be considered during the clinical assessment. Tamponade is not an all-or-nothing diagnosis, but instead should be viewed along a continuum of progressively worsening haemodynamics.
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32

Lee, Olivia T., Jennifer N. Wu, Frederick J. Meyers, and Christopher P. Evans. Genitourinary aspects of palliative care. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0084.

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Genitourinary tract diseases in the palliative care setting most commonly involve urinary tract obstruction, intractable bleeding, fistulae, and bladder-associated pain. Sources of obstruction in the lower urinary tract include benign prostatic hyperplasia, invasive prostate or bladder cancer, urethral stricture, or bladder neck contracture. Upper tract obstruction includes intraluminal or extraluminal blockage of the renal collecting system and ureters, such as transitional cell carcinoma, fibroepithelial polyps, stricture, stones, pelvic or retroperitoneal malignancy, fibrosis, or prior radiation. Untreated, obstructive uropathy leads to elevated bladder, ureter, and kidney pressures, bladder dysfunction, urolithiasis, renal failure, pyelonephritis, or urosepsis. Intractable haematuria can cause problematic anaemia, frequent transfusions, clot retention, haemorrhagic shock, and death. In addition, urinary tract fistulae such as vesicovaginal and vesicoenteric fistulae are common in patients who have had prior pelvic surgery or radiation especially in the setting of immunocompromise, poor nutrition, and infection. Untreated, these symptoms lead to rash, skin breakdown, ulcers, chronic infection, and sepsis. Lastly, pelvic and bladder pain, depending on aetiology can be treated with oral medications, intravesical therapies, or surgical therapies such as palliative resection or urinary diversion. Selection of tests and treatment modalities in the palliative care setting should be based on using the least invasive means to achieve the most relief in suffering. Some genitourinary conditions are potentially fatal, and in the acute or subacute setting, require re-evaluation of the end-of-life goals and wishes of the patient and family.
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33

Supply of Blood for Transfusion in Latin America and Caribbean Countries 2016-2017. Organización Panamericana de la Salud, 2020. http://dx.doi.org/10.37774/9789275121719.

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Blood transfusions are necessary to improve or save the lives of children with severe anemia, mothers in obstetric emergencies, patients with hemoglobinopathies, cancer patients, transplant patients, patients with chronic age-related diseases, such as bleeding caused by vascular problems and orthopedic surgeries, people injured in accidents, among other causes. Supply and access to safe blood for transfusions are closely related to the organization and degree of development of blood services, with the governance and participation of society through voluntary unpaid donation. Since 2004, the Pan American Health Organization (PAHO) has been collecting and publishing indicators related to blood supply in the countries of Latin America and the Caribbean. In 2014, the countries of the Region of the Americas reaffirmed their commitment to universal health through the approval of the Action Plan for Universal Access to Safe Blood 2014-2019, approved by the 53rd Directing Council held in October 2014 (CD53.6), this plan promotes universal access to safe blood for transfusion in the region, through unpaid voluntary donations, the organization of blood services, the implementation of quality and safety standards and the implementation of governance actions. The data presented here allows monitoring and reporting on progress and limitations in the implementation of the Action Plan for Universal Access to Safe Blood. Furthermore, it is hoped that these data will promote the analysis and evaluation of the indicators at the national and subregional levels, and that strategies that improve blood safety and accessibility to transfusions will be strengthened or modified. The information was provided by the authorities of the countries and corresponds to the years 2016 and 2017.
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34

King, Stephen. Night Shift. Book Club Associates, 1991.

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35

King, Stephen. Nachtschicht. Bastei-Lübbe, 1988.

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36

King, Stephen. Nachtschicht. Kurzgeschichten. Lübbe, 2002.

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37

El umbral de la noche. 2nd ed. Barcelona, Spain: Debolsillo, 2012.

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38

King, Stephen. Nochnaya smena. AST, 2001.

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39

Night Shift. 2009.

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40

King, Stephen. Nightshift Stephen King. Hodder & Stoughton General Division, 1991.

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41

King, Stephen. Night Shift. Hodder Paperback, 2008.

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42

King, S. Nochnaya smena. AST, 2005.

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43

King, Stephen. El Umbral De La Noche. Plaza & Janes Editores, 1991.

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44

King, Stephen. El umbral de la noche. Solaris, 1994.

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45

King, Stephen. Night Shift (Silhouette Sensation). Chivers North America, 1995.

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46

Nachtschicht: "Short Shocker" von Amerikas aufregendstem Autor. Bastei Lübbe, 1994.

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47

El umbral de la noche. Orbis-Fabbri, 1994.

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48

King, Stephen. Night Shift. Tandem Library, 1999.

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49

King, Stephen. Night Shift. Signet, 1986.

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50

Ночная смена. Moscow, Russia: act, 1999.

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