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Journal articles on the topic 'Biosensiing'

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Author: Grafiati

Published: 1 April 2023

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1

Kumar, Ravinder, Somvir ., Surender Singh, and Kulwant . "A Review on application of Nanoscience for Biosensing." International Journal of Engineering Research 3, no. 4 (April 1, 2014): 279–85. http://dx.doi.org/10.17950/ijer/v3s4/423.

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2

Zhou Xue, 周雪, 闫欣 Yan Xin, 张学楠 Zhang Xuenan, 王方 Wang Fang, 李曙光 Li Shuguang, 郎雷 Lang Lei, and 程同蕾 Cheng Tonglei. "软玻璃光纤在生物传感领域应用的研究进展." Laser & Optoelectronics Progress 58, no. 15 (2021): 1516019. http://dx.doi.org/10.3788/lop202158.1516019.

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3

P.Sangeetha, P. Sangeetha, and Dr A. Vimala Juliet. "Biosensing by Cantilever Resonator for Disease Causing Pathogen Detection." Indian Journal of Applied Research 4, no. 3 (October 1, 2011): 174–75. http://dx.doi.org/10.15373/2249555x/mar2014/51.

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4

Curtin, Kathrine, Bethany J. Fike, Brandi Binkley, Toktam Godary, and Peng Li. "Recent Advances in Digital Biosensing Technology." Biosensors 12, no. 9 (August 23, 2022): 673. http://dx.doi.org/10.3390/bios12090673.

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Digital biosensing assays demonstrate remarkable advantages over conventional biosensing systems because of their ability to achieve single-molecule detection and absolute quantification. Unlike traditional low-abundance biomarking screening, digital-based biosensing systems reduce sample volumes significantly to the fL-nL level, which vastly reduces overall reagent consumption, improves reaction time and throughput, and enables high sensitivity and single target detection. This review presents the current technology for compartmentalizing reactions and their applications in detecting proteins and nucleic acids. We also analyze existing challenges and future opportunities associated with digital biosensing and research opportunities for developing integrated digital biosensing systems.

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5

Wu, Jiyun, and Qiuyao Wu. "The Review of Biosensor and its Application in the Diagnosis of COVID-19." E3S Web of Conferences 290 (2021): 03028. http://dx.doi.org/10.1051/e3sconf/202129003028.

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The objective of this article is to summarize the available technologies for biosensing applications in COVID-19. The article is divided into three parts, an introduction to biosensing technologies, applications of mainstream biosensing technologies and a review of biosensing applications in COVID-19. The introduction of biosensors presents the history of inventing the biosensing technology, which refers to the ISFET. The resonant biosensor with the example of MEMS. the principle of optical biosensor, and the thermal biosensor. In the second part, the main use of biosensing techniques, it was discussed the field of the food industry, environmental monitoring, and the medical industry. In the part of biosensor application in COVID-19, it was mentioned that the technique of POCT, the use of RT-LAMP-NBS in the early detection in China, and the use in gRT-PCR for the detection of the DNA code to determine the presence of pathogen of COVLD-19 in the human body.

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6

Howell, Noura, John Chuang, Abigail De Kosnik, Greg Niemeyer, and Kimiko Ryokai. "Emotional Biosensing." Proceedings of the ACM on Human-Computer Interaction 2, CSCW (November 2018): 1–25. http://dx.doi.org/10.1145/3274338.

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7

Mejía-Salazar, J. R., and Osvaldo N. Oliveira. "Plasmonic Biosensing." Chemical Reviews 118, no. 20 (September 24, 2018): 10617–25. http://dx.doi.org/10.1021/acs.chemrev.8b00359.

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8

Fink, Dietmar, Gerardo Munoz Hernandez, Jiri Vacik, and Lital Alfonta. "Pulsed Biosensing." IEEE Sensors Journal 11, no. 4 (April 2011): 1084–87. http://dx.doi.org/10.1109/jsen.2010.2073461.

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9

Bellassai, Noemi, Roberta D’Agata, and Giuseppe Spoto. "Novel nucleic acid origami structures and conventional molecular beacon–based platforms: a comparison in biosensing applications." Analytical and Bioanalytical Chemistry 413, no. 24 (April 6, 2021): 6063–77. http://dx.doi.org/10.1007/s00216-021-03309-4.

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AbstractNucleic acid nanotechnology designs and develops synthetic nucleic acid strands to fabricate nanosized functional systems. Structural properties and the conformational polymorphism of nucleic acid sequences are inherent characteristics that make nucleic acid nanostructures attractive systems in biosensing. This review critically discusses recent advances in biosensing derived from molecular beacon and DNA origami structures. Molecular beacons belong to a conventional class of nucleic acid structures used in biosensing, whereas DNA origami nanostructures are fabricated by fully exploiting possibilities offered by nucleic acid nanotechnology. We present nucleic acid scaffolds divided into conventional hairpin molecular beacons and DNA origami, and discuss some relevant examples by focusing on peculiar aspects exploited in biosensing applications. We also critically evaluate analytical uses of the synthetic nucleic acid structures in biosensing to point out similarities and differences between traditional hairpin nucleic acid sequences and DNA origami. Graphical abstract

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10

Soleymani, Leyla, Sudip Saha, Amanda Victorious, Sadman Sakib, and Igor Zhitomirsky. "(Invited) Development of New Strategies for Bringing Photoelectrochemical Biosensing to the Point-of-Need." ECS Meeting Abstracts MA2022-01, no. 53 (July 7, 2022): 2178. http://dx.doi.org/10.1149/ma2022-01532178mtgabs.

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Photoelectrochemistry combines light excitation with electrochemical readout for lowering the bias voltage needed for performing electrochemical reactions. As a result, when used in biosensing, photoelectrochemical signal readout reduces the background signals, lowering the limit-of-detection of such biosensors. To enable photoelectrochemical (PEC) signal readout to be applied to point-of-need biosensing, we have taken a three tiered approach focused on improving the understanding of signal transduction in PEC Biosensing, developing label-free assays, and creating handheld readout platforms. In this work, we developed a system using DNA as a nano-ruler to control the distance between plasmonic nanoparticles and PEC electrodes. This system was used to rationally-design PEC material systems for signal-on biosensing. Using this materials architecture, we developed a signal-on biosensor without target labeling for detecting DNA hybridization. This assay uses sequential DNA hybridization to generate a PEC signal. First, the DNA target is captured on probe-modified photoelectrodes. This is followed by hybridization of the unbound probes with DNA strands modified with plasmonic labels. The plasmonic label modulates the PEC signal, increasing the measured PEC current at low target concentrations. To enable biosensing at the point-of-need, we also developed a handheld PEC reader. The integration of plasmonic nanoparticles with PEC electrodes, label-free DNA assays, and handheld PEC readout paves the way toward bringing point-of-need PEC Biosensing.

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11

Ng, Keng Wooi, and S. Moein Moghimi. "Skin Biosensing and Bioanalysis: what the Future Holds." Precision Nanomedicine 1, no. 2 (July 26, 2018): 124–27. http://dx.doi.org/10.33218/prnano1(2).180709.1.

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Wearable skin biosensors have important applications in health monitoring, medical treatment and theranostics. There has been a rapid growth in the development of novel biosensing and bioanalytical techniques in recent years, much of it underpinned by recent advancements in nanotechnology. As the two related disciplines continue to co-evolve, we take a timely look at some notable developments in skin biosensing/bioanalysis, scan the horizon for emerging nanotechnologies, and discuss how they may influence the future of biosensing/bioanalysis in the skin.

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12

Yang, Yun Jun, and Zhong Feng Gao. "Bio-inspired Superwettable Surface for the Detection of Cancer Biomarker: A Mini Review." Technology in Cancer Research & Treatment 21 (January 2022): 153303382211106. http://dx.doi.org/10.1177/15330338221110670.

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Inspired by nature, superwettable material-based biosensors have aroused wide interests due to their potential in cancer biomarker detection. This mini review mainly summarized the superwettable materials as novel biosensing substrates for the development of evaporation-induced enrichment-based signal amplification and visual biosensing method. Biosensing applications based on the superhydrophobic surfaces, superwettable micropatterned surfaces, and slippery lubricant-infused porous surfaces for various cancer biomarker detections were described in detail. Finally, an insight of remaining challenges and perspectives of superwettable biosensor is proposed.

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13

Ye, Shun, Shilun Feng, Liang Huang, and Shengtai Bian. "Recent Progress in Wearable Biosensors: From Healthcare Monitoring to Sports Analytics." Biosensors 10, no. 12 (December 15, 2020): 205. http://dx.doi.org/10.3390/bios10120205.

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Recent advances in lab-on-a-chip technology establish solid foundations for wearable biosensors. These newly emerging wearable biosensors are capable of non-invasive, continuous monitoring by miniaturization of electronics and integration with microfluidics. The advent of flexible electronics, biochemical sensors, soft microfluidics, and pain-free microneedles have created new generations of wearable biosensors that explore brand-new avenues to interface with the human epidermis for monitoring physiological status. However, these devices are relatively underexplored for sports monitoring and analytics, which may be largely facilitated by the recent emergence of wearable biosensors characterized by real-time, non-invasive, and non-irritating sensing capacities. Here, we present a systematic review of wearable biosensing technologies with a focus on materials and fabrication strategies, sampling modalities, sensing modalities, as well as key analytes and wearable biosensing platforms for healthcare and sports monitoring with an emphasis on sweat and interstitial fluid biosensing. This review concludes with a summary of unresolved challenges and opportunities for future researchers interested in these technologies. With an in-depth understanding of the state-of-the-art wearable biosensing technologies, wearable biosensors for sports analytics would have a significant impact on the rapidly growing field—microfluidics for biosensing.

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14

MO, YANG, and TAN FEI. "NANOPOROUS MEMBRANE FOR BIOSENSING APPLICATIONS." Nano LIFE 02, no. 01 (March 2012): 1230003. http://dx.doi.org/10.1142/s1793984411000323.

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Synthetic nanoporous membranes have been used in numerous biosensing applications, such as glucose detection, nucleic acid detection, bacteria detection, and cell-based sensing. The increased surface affinity area and enhanced output sensing signals make the nanoporous membranes increasingly attractive as biosensing platforms. Surface modification techniques can be used to improve surface properties for realizable bioanalyte immobilization, conjugation, and detection. Combined with realizable detection techniques such as electrochemical and optical detection methods, nanoporous membrane–based biosensors have advantages, including rapid response, high sensitivity, and low cost. In this paper, an overview of nanoporous membranes for biosensing application is given. Types of nanoporous membranes including polymer membranes, inorganic membranes, membranes with nanopores fabricated using nanolithography, and nanotube-based membranes are introduced. The fabrication techniques of nanoporous membranes are also discussed. The key requirements of nanoporous membranes for biosensing applications include surface functionality for bioanalyte immobilization, biocompatibility, mechanical and chemical stability, and anti-biofouling capability. The recent advances and development of nanoporous membrane–based biosensors are discussed, especially for the sensing mechanism and surface functionalization strategies. Finally, the challenges and future development of nanoporous membrane for biosensing applications are discussed.

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15

Lin, Yanna, Yong Huang, and Xuwei Chen. "Recent Advances in Metal-Organic Frameworks for Biomacromolecule Sensing." Chemosensors 10, no. 10 (October 11, 2022): 412. http://dx.doi.org/10.3390/chemosensors10100412.

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Metal-organic frameworks (MOFs) are emerging class of ordered porous materials consisting of metal clusters and organic ligands. High porosity, adjustable topology, composition and structural diversity have earned MOFs extensive popularity in various fields, including biosensing. This review focuses on understanding the role of MOFs in biosensing, mainly as efficient signal probes, nanozymes and nanocarriers. It also provides the recent advances of MOFs in sensing biomacromolecules such as protein, peptide, DNA, RNA and polysaccharide. In addition, the challenge, and perspectives, of MOFs in biosensing are presented, based on our opinion.

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16

Han, Xue, Kun Liu, and Changsen Sun. "Plasmonics for Biosensing." Materials 12, no. 9 (April 30, 2019): 1411. http://dx.doi.org/10.3390/ma12091411.

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Techniques based on plasmonic resonance can provide label-free, signal enhanced, and real-time sensing means for bioparticles and bioprocesses at the molecular level. With the development in nanofabrication and material science, plasmonics based on synthesized nanoparticles and manufactured nano-patterns in thin films have been prosperously explored. In this short review, resonance modes, materials, and hybrid functions by simultaneously using electrical conductivity for plasmonic biosensing techniques are exclusively reviewed for designs containing nanovoids in thin films. This type of plasmonic biosensors provide prominent potential to achieve integrated lab-on-a-chip which is capable of transporting and detecting minute of multiple bio-analytes with extremely high sensitivity, selectivity, multi-channel and dynamic monitoring for the next generation of point-of-care devices.

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17

McConnell, Erin M., Ioana Cozma, Quanbing Mou, John D. Brennan, Yi Lu, and Yingfu Li. "Biosensing with DNAzymes." Chemical Society Reviews 50, no. 16 (2021): 8954–94. http://dx.doi.org/10.1039/d1cs00240f.

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This article provides a comprehensive review of biosensing with DNAzymes, providing an overview of different sensing applications while highlighting major progress and seminal contributions to the field of portable biosensor devices and point-of-care diagnostics.

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18

Yan, Xiaodong, Hai-Feng Ji, and Thomas Thundat. "Microcantilever (MCL) Biosensing." Current Analytical Chemistry 2, no. 3 (July 1, 2006): 297–307. http://dx.doi.org/10.2174/157341106777698251.

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19

Telford, Mark. "Biosensing, biocidal ‘nanocarpets’." Materials Today 7, no. 12 (December 2004): 10. http://dx.doi.org/10.1016/s1369-7021(04)00611-x.

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20

Pumera, Martin. "Graphene in biosensing." Materials Today 14, no. 7-8 (July 2011): 308–15. http://dx.doi.org/10.1016/s1369-7021(11)70160-2.

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21

Scheggi, A. M., and A. G. Mignani. "Optical fiber biosensing." Optics News 15, no. 11 (November 1, 1989): 28. http://dx.doi.org/10.1364/on.15.11.000028.

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22

Qi, Honglan, and Chengxiao Zhang. "Electrogenerated Chemiluminescence Biosensing." Analytical Chemistry 92, no. 1 (December 2, 2019): 524–34. http://dx.doi.org/10.1021/acs.analchem.9b03425.

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23

Marquette, Christophe A., and Loïc J. Blum. "Electro-chemiluminescent biosensing." Analytical and Bioanalytical Chemistry 390, no. 1 (October 2, 2007): 155–68. http://dx.doi.org/10.1007/s00216-007-1631-2.

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24

Lei, Jianping, and Huangxian Ju. "Nanotubes in biosensing." Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 2, no. 5 (August 16, 2010): 496–509. http://dx.doi.org/10.1002/wnan.94.

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25

Marchisio, Mario Andrea, and Fabian Rudolf. "Synthetic biosensing systems." International Journal of Biochemistry & Cell Biology 43, no. 3 (March 2011): 310–19. http://dx.doi.org/10.1016/j.biocel.2010.11.012.

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26

Ron, Eliora Z. "Biosensing environmental pollution." Current Opinion in Biotechnology 18, no. 3 (June 2007): 252–56. http://dx.doi.org/10.1016/j.copbio.2007.05.005.

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27

Mondal, Jagannath, Jeong Man An, Sachin S. Surwase, Kushal Chakraborty, Sabuj Chandra Sutradhar, Joon Hwang, Jaewook Lee, and Yong-Kyu Lee. "Carbon Nanotube and Its Derived Nanomaterials Based High Performance Biosensing Platform." Biosensors 12, no. 9 (September 6, 2022): 731. http://dx.doi.org/10.3390/bios12090731.

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After the COVID-19 pandemic, the development of an accurate diagnosis and monitoring of diseases became a more important issue. In order to fabricate high-performance and sensitive biosensors, many researchers and scientists have used many kinds of nanomaterials such as metal nanoparticles (NPs), metal oxide NPs, quantum dots (QDs), and carbon nanomaterials including graphene and carbon nanotubes (CNTs). Among them, CNTs have been considered important biosensing channel candidates due to their excellent physical properties such as high electrical conductivity, strong mechanical properties, plasmonic properties, and so on. Thus, in this review, CNT-based biosensing systems are introduced and various sensing approaches such as electrochemical, optical, and electrical methods are reported. Moreover, such biosensing platforms showed excellent sensitivity and high selectivity against not only viruses but also virus DNA structures. So, based on the amazing potential of CNTs-based biosensing systems, healthcare and public health can be significantly improved.

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28

Maniya, Nalin H. "Recent Advances in Porous Silicon Based Optical Biosensors." REVIEWS ON ADVANCED MATERIALS SCIENCE 53, no. 1 (January 1, 2018): 49–73. http://dx.doi.org/10.1515/rams-2018-0004.

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Abstract PSi structures have unique physical and optical properties, which are being exploited for a numerous biomedical applications including biosensing, bioimaging, tissue engineering, and drug delivery. Different PSi optical structures can be fabricated to improve the sensitivity of the optical measurements. A very high surface area per volume of PSi can be used for the higher loading of target analytes in a small sensor area, which helps in increasing sensitivity and allows the miniaturization of biosensor. The specificity of PSi biosensor to the target analyte can be inferred by immobilizing the corresponding bioreceptor such as DNA, enzyme, or antibody via different conjugation chemistries. Finally, PSi is biocompatible material that offers additional advantage in comparison to other sensing platforms for in vivo implantable biosensing applications. This paper reviews fabrication, surface modification, biofunctionalization, and optical biosensing applications of PSi structures with special emphasis on in vivo and PSi photonic particles biosensing.

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29

Luong, John H. T., Tarun Narayan, Shipra Solanki, and Bansi D. Malhotra. "Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications." Journal of Functional Biomaterials 11, no. 4 (September 25, 2020): 71. http://dx.doi.org/10.3390/jfb11040071.

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Conducting polymers (CPs) have been at the center of research owing to their metal-like electrochemical properties and polymer-like dispersion nature. CPs and their composites serve as ideal functional materials for diversified biomedical applications like drug delivery, tissue engineering, and diagnostics. There have also been numerous biosensing platforms based on polyaniline (PANI), polypyrrole (PPY), polythiophene (PTP), and their composites. Based on their unique properties and extensive use in biosensing matrices, updated information on novel CPs and their role is appealing. This review focuses on the properties and performance of biosensing matrices based on CPs reported in the last three years. The salient features of CPs like PANI, PPY, PTP, and their composites with nanoparticles, carbon materials, etc. are outlined along with respective examples. A description of mediator conjugated biosensor designs and enzymeless CPs based glucose sensing has also been included. The future research trends with required improvements to improve the analytical performance of CP-biosensing devices have also been addressed.

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30

Li, Lingling, Bing Han, Ying Wang, Hai Shi, Jing Zhao, and Genxi Li. "Gold Nanoparticles-based Bio-Sensing Methods for Tumor-related Biomedical Applications in Bodily Fluids." Current Nanoscience 16, no. 3 (April 2, 2020): 425–40. http://dx.doi.org/10.2174/1573413715666190206152717.

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Background: Cancer is one of most dangerous diseases that seriously threaten human health, while tumor biomarkers provide important information for clinical diagnosis and treatment of cancers. Given the low abundance of tumor biomarkers in the bodily fluids at the early stage of cancers, it is particularly important to develop bio sensing methods for accurate measurement of tumor biomarkers with high sensitivity. Objective: Nowadays, gold nanoparticles (AuNPs) that have remarkable physical and chemical properties are extensively used in the design of biosensing strategies. In this context, we mainly review the research progress of AuNPs-based biosensing methods for tumor-related biomedical applications in bodily fluids in recent years. Results: Optical, electrochemical and mass spectrometric biosensing methods using AuNPs are widely used for excellent performances in the assay of tumor biomarkers. Conclusion: The existing methods demonstrate high clinical value, while challenges and expectation of biosensing method in tumor-related biomedical application are also discussed.

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31

Hoang Trung Chau, Tin, Dung Hoang Anh Mai, Diep Ngoc Pham, Hoa Thi Quynh Le, and Eun Yeol Lee. "Developments of Riboswitches and Toehold Switches for Molecular Detection—Biosensing and Molecular Diagnostics." International Journal of Molecular Sciences 21, no. 9 (April 30, 2020): 3192. http://dx.doi.org/10.3390/ijms21093192.

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Riboswitches and toehold switches are considered to have potential for implementation in various fields, i.e., biosensing, metabolic engineering, and molecular diagnostics. The specific binding, programmability, and manipulability of these RNA-based molecules enable their intensive deployments in molecular detection as biosensors for regulating gene expressions, tracking metabolites, or detecting RNA sequences of pathogenic microorganisms. In this review, we will focus on the development of riboswitches and toehold switches in biosensing and molecular diagnostics. This review introduces the operating principles and the notable design features of riboswitches as well as toehold switches. Moreover, we will describe the advances and future directions of riboswitches and toehold switches in biosensing and molecular diagnostics.

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32

Kaur, Manpreet, Jyoti Gaba, Komal Singh, Yashika Bhatia, Anoop Singh, and Narinder Singh. "Recent Advances in Recognition Receptors for Electrochemical Biosensing of Mycotoxins—A Review." Biosensors 13, no. 3 (March 17, 2023): 391. http://dx.doi.org/10.3390/bios13030391.

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Mycotoxins are naturally occurring toxic secondary metabolites produced by fungi in cereals and foodstuffs during the stages of cultivation and storage. Electrochemical biosensing has emerged as a rapid, efficient, and economical approach for the detection and quantification of mycotoxins in different sample media. An electrochemical biosensor consists of two main units, a recognition receptor and a signal transducer. Natural or artificial antibodies, aptamers, molecularly imprinted polymers (MIP), peptides, and DNAzymes have been extensively employed as selective recognition receptors for the electrochemical biosensing of mycotoxins. This article affords a detailed discussion of the recent advances and future prospects of various types of recognition receptors exploited in the electrochemical biosensing of mycotoxins.

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33

Shu, Jian, Zhenli Qiu, Qian Zhou, and Dianping Tang. "A chemiresistive thin-film translating biological recognition into electrical signals: an innovative signaling mode for contactless biosensing." Chemical Communications 55, no. 22 (2019): 3262–65. http://dx.doi.org/10.1039/c9cc00298g.

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An innovative signaling mode in which a chemiresistive thin-film electrode monitors the specific gaseous component that results from a biological recognition event to indirectly detect targets in the liquid phase is developed for highly-efficient contactless biosensing. This signaling mode may open a new horizon in designing robust biosensing devices for bioanalysis.

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Cardoso, Ana R., Manuela F. Frasco, Verónica Serrano, Elvira Fortunato, and Maria Goreti Ferreira Sales. "Molecular Imprinting on Nanozymes for Sensing Applications." Biosensors 11, no. 5 (May 13, 2021): 152. http://dx.doi.org/10.3390/bios11050152.

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As part of the biomimetic enzyme field, nanomaterial-based artificial enzymes, or nanozymes, have been recognized as highly stable and low-cost alternatives to their natural counterparts. The discovery of enzyme-like activities in nanomaterials triggered a broad range of designs with various composition, size, and shape. An overview of the properties of nanozymes is given, including some examples of enzyme mimics for multiple biosensing approaches. The limitations of nanozymes regarding lack of selectivity and low catalytic efficiency may be surpassed by their easy surface modification, and it is possible to tune specific properties. From this perspective, molecularly imprinted polymers have been successfully combined with nanozymes as biomimetic receptors conferring selectivity and improving catalytic performance. Compelling works on constructing imprinted polymer layers on nanozymes to achieve enhanced catalytic efficiency and selective recognition, requisites for broad implementation in biosensing devices, are reviewed. Multimodal biomimetic enzyme-like biosensing platforms can offer additional advantages concerning responsiveness to different microenvironments and external stimuli. Ultimately, progress in biomimetic imprinted nanozymes may open new horizons in a wide range of biosensing applications.

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35

Kim, Youngsun, John Gonzales, and Yuebing Zheng. "Optical Biosensing: Sensitivity‐Enhancing Strategies in Optical Biosensing (Small 4/2021)." Small 17, no. 4 (January 2021): 2170016. http://dx.doi.org/10.1002/smll.202170016.

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36

Huang, H. T., P. Garu, C. H. Li, W. C. Chang, B. W. Chen, S. Y. Sung, C. M. Lee, et al. "Magnetoresistive Biosensors for Direct Detection of Magnetic Nanoparticle Conjugated Biomarkers on a Chip." SPIN 09, no. 02 (June 2019): 1940002. http://dx.doi.org/10.1142/s2010324719400022.

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In this review, we introduce various magnetic biosensors that have been developed. We first explain the advantages of magnetic biosensing and their general operating principles as well as the biolabeling technique for magnetic nanoparticles. Next, we focus on magnetoresistive biosensing technologies because magnetoresistive biosensors will be an essential development direction due to the demand for miniaturization and portable lab-on-a-chip devices. The magnetoresistive effects employed in biosensing include anisotropic magnetoresistance, giant magnetoresistance and tunneling magnetoresistance. In addition to magnetoresistive sensors, the advantages and disadvantages of some nonmagnetoresistive magnetic biosensors are discussed and compared. Finally, we introduce research on integrating magnetic biosensors into the microfluidic laboratory-on-a-chip systems and comment on future development trends.

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Miyagawa, Akihisa, and Tetsuo Okada. "Biosensing Strategies Based on Particle Behavior." Chemosensors 11, no. 3 (March 3, 2023): 172. http://dx.doi.org/10.3390/chemosensors11030172.

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Micro/nanoparticles are widely used as useful biosensing platforms. Molecular recognition efficiently occurs on their surface, where ligand molecules are accumulated and, in some cases, well organized. The interactions that occur on or in the micro/nanoparticle significantly alter its physicochemical properties. Therefore, highly sensitive detection is possible based on such changes. Usual biosensors convert molecular or biological responses into optical or electrochemical signals. Particle-based biosensing can utilize a variety of other transducing mechanisms, including the changes in the levitation position of particles in physical fields, diffusion behavior, aggregation or dissociation, changes in the surface charge, and changes in size. We review the recent developments in biosensing based on various aspects of particle behavior.

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38

Kumar, Santosh, Zhi Wang, Wen Zhang, Xuecheng Liu, Muyang Li, Guoru Li, Bingyuan Zhang, and Ragini Singh. "Optically Active Nanomaterials and Its Biosensing Applications—A Review." Biosensors 13, no. 1 (January 4, 2023): 85. http://dx.doi.org/10.3390/bios13010085.

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This article discusses optically active nanomaterials and their optical biosensing applications. In addition to enhancing their sensitivity, these nanomaterials also increase their biocompatibility. For this reason, nanomaterials, particularly those based on their chemical compositions, such as carbon-based nanomaterials, inorganic-based nanomaterials, organic-based nanomaterials, and composite-based nanomaterials for biosensing applications are investigated thoroughly. These nanomaterials are used extensively in the field of fiber optic biosensing to improve response time, detection limit, and nature of specificity. Consequently, this article describes contemporary and application-based research that will be of great use to researchers in the nanomaterial-based optical sensing field. The difficulties encountered during the synthesis, characterization, and application of nanomaterials are also enumerated, and their future prospects are outlined for the reader’s benefit.

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39

Pasche, Stéphanie, Bastien Schyrr, Bernard Wenger, Emmanuel Scolan, Réal Ischer, and Guy Voirin. "Smart Textiles with Biosensing Capabilities." Advances in Science and Technology 80 (September 2012): 129–35. http://dx.doi.org/10.4028/www.scientific.net/ast.80.129.

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Real-time, on-body measurement using minimally invasive biosensors opens up new perspectives for diagnosis and disease monitoring. Wearable sensors are placed in close contact with the body, performing analyses in accessible biological fluids (wound exudates, sweat). In this context, a network of biosensing optical fibers woven in textile enables the fabric to measure biological parameters in the surrounding medium. Optical fibers are attractive in view of their flexibility and easy integration for on-body monitoring. Biosensing fibers are obtained by modifying standard optical fibers with a sensitive layer specific to biomarkers. Detection is based on light absorption of the sensing fiber, placing a light source and a detector at both extremities of the fiber. Biosensing optical fibers have been developed for the in situ monitoring of wound healing, measuring pH and the activity of proteases in exudates. Other developments aim at the design of sensing patches based on functionalized, porous sol-gel layers, which can be deposited onto textiles and show optical changes in response to biomarkers. Biosensing textiles present interesting perspectives for innovative healthcare monitoring. Wearable sensors will provide access to new information from the body in real time, to support diagnosis and therapy.

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Gheorghiu, Mihaela, Cristina Polonschii, Octavian Popescu, and Eugen Gheorghiu. "Advanced Optogenetic-Based Biosensing and Related Biomaterials." Materials 14, no. 15 (July 26, 2021): 4151. http://dx.doi.org/10.3390/ma14154151.

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The ability to stimulate mammalian cells with light, brought along by optogenetic control, has significantly broadened our understanding of electrically excitable tissues. Backed by advanced (bio)materials, it has recently paved the way towards novel biosensing concepts supporting bio-analytics applications transversal to the main biomedical stream. The advancements concerning enabling biomaterials and related novel biosensing concepts involving optogenetics are reviewed with particular focus on the use of engineered cells for cell-based sensing platforms and the available toolbox (from mere actuators and reporters to novel multifunctional opto-chemogenetic tools) for optogenetic-enabled real-time cellular diagnostics and biosensor development. The key advantages of these modified cell-based biosensors concern both significantly faster (minutes instead of hours) and higher sensitivity detection of low concentrations of bioactive/toxic analytes (below the threshold concentrations in classical cellular sensors) as well as improved standardization as warranted by unified analytic platforms. These novel multimodal functional electro-optical label-free assays are reviewed among the key elements for optogenetic-based biosensing standardization. This focused review is a potential guide for materials researchers interested in biosensing based on light-responsive biomaterials and related analytic tools.

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Li, Muyang, Ragini Singh, Yiran Wang, Carlos Marques, Bingyuan Zhang, and Santosh Kumar. "Advances in Novel Nanomaterial-Based Optical Fiber Biosensors—A Review." Biosensors 12, no. 10 (October 8, 2022): 843. http://dx.doi.org/10.3390/bios12100843.

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This article presents a concise summary of current advancements in novel nanomaterial-based optical fiber biosensors. The beneficial optical and biological properties of nanomaterials, such as nanoparticle size-dependent signal amplification, plasmon resonance, and charge-transfer capabilities, are widely used in biosensing applications. Due to the biocompatibility and bioreceptor combination, the nanomaterials enhance the sensitivity, limit of detection, specificity, and response time of sensing probes, as well as the signal-to-noise ratio of fiber optic biosensing platforms. This has established a practical method for improving the performance of fiber optic biosensors. With the aforementioned outstanding nanomaterial properties, the development of fiber optic biosensors has been efficiently promoted. This paper reviews the application of numerous novel nanomaterials in the field of optical fiber biosensing and provides a brief explanation of the fiber sensing mechanism.

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Zhou, Lixia, Xiaoxiao He, Dinggeng He, Kemin Wang, and Dilan Qin. "Biosensing Technologies forMycobacterium tuberculosisDetection: Status and New Developments." Clinical and Developmental Immunology 2011 (2011): 1–8. http://dx.doi.org/10.1155/2011/193963.

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Biosensing technologies promise to improveMycobacterium tuberculosis(M. tuberculosis) detection and management in clinical diagnosis, food analysis, bioprocess, and environmental monitoring. A variety of portable, rapid, and sensitive biosensors with immediate “on-the-spot” interpretation have been developed forM. tuberculosisdetection based on different biological elements recognition systems and basic signal transducer principles. Here, we present a synopsis of current developments of biosensing technologies forM. tuberculosisdetection, which are classified on the basis of basic signal transducer principles, including piezoelectric quartz crystal biosensors, electrochemical biosensors, and magnetoelastic biosensors. Special attention is paid to the methods for improving the framework and analytical parameters of the biosensors, including sensitivity and analysis time as well as automation of analysis procedures. Challenges and perspectives of biosensing technologies development forM. tuberculosisdetection are also discussed in the final part of this paper.

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Moore, Phoebe. "Review: Dawn Nafus (ed.), Quantified: Biosensing Technologies in Everyday Life." Theory, Culture & Society 34, no. 7-8 (October 10, 2017): 269–75. http://dx.doi.org/10.1177/0263276417735157.

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We have, in the 21st century, moved into a new series of fascinations with biosensing, where our autonomic systems or an autonomic ‘self’, largely out of bounds for our own knowledge and understanding before now, are available. ‘Autonomic’ refers to the nervous system of a physiological self, but the extent of our autonomic selves would not otherwise be knowable or known but through sensory tracking devices now available to us. Biosensing, biohacking, biometrics and biopower are all part of a contemporary movement of intimate and intensified measure and are terms that Dawn Nafus's collection Quantified: Biosensing Technologies in Everyday Life deals with. The book discusses questions of measurement and tracking with the use of sensory technology and methods. This review considers where this collection sits in the literature and theoretical debates.

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Thangamuthu, Madasamy, Kuan Yu Hsieh, Priyank V. Kumar, and Guan-Yu Chen. "Graphene- and Graphene Oxide-Based Nanocomposite Platforms for Electrochemical Biosensing Applications." International Journal of Molecular Sciences 20, no. 12 (June 18, 2019): 2975. http://dx.doi.org/10.3390/ijms20122975.

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Graphene and its derivatives such as graphene oxide (GO) and reduced GO (rGO) offer excellent electrical, mechanical and electrochemical properties. Further, due to the presence of high surface area, and a rich oxygen and defect framework, they are able to form nanocomposites with metal/semiconductor nanoparticles, metal oxides, quantum dots and polymers. Such nanocomposites are becoming increasingly useful as electrochemical biosensing platforms. In this review, we present a brief introduction on the aforementioned graphene derivatives, and discuss their synthetic strategies and structure–property relationships important for biosensing. We then highlight different nanocomposite platforms that have been developed for electrochemical biosensing, introducing enzymatic biosensors, followed by non-enzymatic biosensors and immunosensors. Additionally, we briefly discuss their role in the emerging field of biomedical cell capture. Finally, a brief outlook on these topics is presented.

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Merkoçi, Arben, Chen-zhong Li, Laura M. Lechuga, and Aydogan Ozcan. "COVID-19 biosensing technologies." Biosensors and Bioelectronics 178 (April 2021): 113046. http://dx.doi.org/10.1016/j.bios.2021.113046.

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Sondhi, Palak, Md Helal Uddin Maruf, and Keith J. Stine. "Nanomaterials for Biosensing Lipopolysaccharide." Biosensors 10, no. 1 (December 21, 2019): 2. http://dx.doi.org/10.3390/bios10010002.

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Lipopolysaccharides (LPS) are endotoxins, hazardous and toxic inflammatory stimulators released from the outer membrane of Gram-negative bacteria, and are the major cause of septic shock giving rise to millions of fatal illnesses worldwide. There is an urgent need to identify and detect these molecules selectively and rapidly. Pathogen detection has been done by traditional as well as biosensor-based methods. Nanomaterial based biosensors can assist in achieving these goals and have tremendous potential. The biosensing techniques developed are low-cost, easy to operate, and give a fast response. Due to extremely small size, large surface area, and scope for surface modification, nanomaterials have been used to target various biomolecules, including LPS. The sensing mechanism can be quite complex and involves the transformation of chemical interactions into amplified physical signals. Many different sorts of nanomaterials such as metal nanomaterials, magnetic nanomaterials, quantum dots, and others have been used for biosensing of LPS and have shown attractive results. This review considers the recent developments in the application of nanomaterials in sensing of LPS with emphasis given mainly to electrochemical and optical sensing.

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Yuan, Liang, and Lei Liu. "Peptide-based electrochemical biosensing." Sensors and Actuators B: Chemical 344 (October 2021): 130232. http://dx.doi.org/10.1016/j.snb.2021.130232.

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Parveen, Ariba, and Jai Prakash. "Biosensing Using Liquid Crystals." Resonance 26, no. 9 (September 2021): 1187–96. http://dx.doi.org/10.1007/s12045-021-1221-1.

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Banciu, Roberta Maria, Nimet Numan, and Alina Vasilescu. "Optical biosensing of lysozyme." Journal of Molecular Structure 1250 (February 2022): 131639. http://dx.doi.org/10.1016/j.molstruc.2021.131639.

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Benabdallah, Gabrielle, and Blair Subbaraman. "Explorations in narrative biosensing." Interactions 29, no. 1 (January 2022): 14–15. http://dx.doi.org/10.1145/3505276.

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