Relevant bibliographies by topics / Biomolecular system

Academic literature on the topic 'Biomolecular system'

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Published: 14 March 2023

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Journal articles on the topic "Biomolecular system"

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Raković, Dejan, Miroljub Dugić, Jasmina Jeknić-Dugić, Milenko Plavšić, Stevo Jaćimovski, and Jovan Šetrajčić. "On Macroscopic Quantum Phenomena in Biomolecules and Cells: From Levinthal to Hopfield." BioMed Research International 2014 (2014): 1–9. http://dx.doi.org/10.1155/2014/580491.

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In the context of the macroscopic quantum phenomena of the second kind, we hereby seek for a solution-in-principle of the long standing problem of the polymer folding, which was considered by Levinthal as (semi)classically intractable. To illuminate it, we applied quantum-chemical and quantum decoherence approaches to conformational transitions. Our analyses imply the existence of novel macroscopic quantum biomolecular phenomena, with biomolecular chain folding in an open environment considered as a subtle interplay between energy and conformation eigenstates of this biomolecule, governed by quantum-chemical and quantum decoherence laws. On the other hand, within an open biological cell, a system of all identical (noninteracting and dynamically noncoupled) biomolecular proteins might be considered as corresponding spatial quantum ensemble of these identical biomolecular processors, providing spatially distributed quantum solution to a single corresponding biomolecular chain folding, whose density of conformational states might be represented as Hopfield-like quantum-holographic associative neural network too (providing an equivalent global quantum-informational alternative to standard molecular-biology local biochemical approach in biomolecules and cells and higher hierarchical levels of organism, as well).
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Hong, Yoochan, Yong-Min Huh, Dae Sung Yoon, and Jaemoon Yang. "Nanobiosensors Based on Localized Surface Plasmon Resonance for Biomarker Detection." Journal of Nanomaterials 2012 (2012): 1–13. http://dx.doi.org/10.1155/2012/759830.

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Localized surface plasmon resonance (LSPR) is induced by incident light when it interacts with noble metal nanoparticles that have smaller sizes than the wavelength of the incident light. Recently, LSPR-based nanobiosensors were developed as tools for highly sensitive, label-free, and flexible sensing techniques for the detection of biomolecular interactions. In this paper, we describe the basic principles of LSPR-based nanobiosensing techniques and LSPR sensor system for biomolecule sensing. We also discuss the challenges using LSPR nanobiosensors for detection of biomolecules as a biomarker.
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Gawthrop, Peter. "Computing Biomolecular System Steady-States." IEEE Transactions on NanoBioscience 17, no. 1 (January 2018): 36–43. http://dx.doi.org/10.1109/tnb.2017.2787486.

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Fujisaki, Hiroshi, Kei Moritsugu, and Yasuhiro Matsunaga. "Exploring Configuration Space and Path Space of Biomolecules Using Enhanced Sampling Techniques—Searching for Mechanism and Kinetics of Biomolecular Functions." International Journal of Molecular Sciences 19, no. 10 (October 15, 2018): 3177. http://dx.doi.org/10.3390/ijms19103177.

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To understand functions of biomolecules such as proteins, not only structures but their conformational change and kinetics need to be characterized, but its atomistic details are hard to obtain both experimentally and computationally. Here, we review our recent computational studies using novel enhanced sampling techniques for conformational sampling of biomolecules and calculations of their kinetics. For efficiently characterizing the free energy landscape of a biomolecule, we introduce the multiscale enhanced sampling method, which uses a combined system of atomistic and coarse-grained models. Based on the idea of Hamiltonian replica exchange, we can recover the statistical properties of the atomistic model without any biases. We next introduce the string method as a path search method to calculate the minimum free energy pathways along a multidimensional curve in high dimensional space. Finally we introduce novel methods to calculate kinetics of biomolecules based on the ideas of path sampling: one is the Onsager–Machlup action method, and the other is the weighted ensemble method. Some applications of the above methods to biomolecular systems are also discussed and illustrated.
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Hradetzky, David, Claas Mueller, and Holger Reinecke. "Interferometric label-free biomolecular detection system." Journal of Optics A: Pure and Applied Optics 8, no. 7 (June 1, 2006): S360—S364. http://dx.doi.org/10.1088/1464-4258/8/7/s11.

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Leinen, Margaret, Francisco Chavez, Raïssa Meyer, Pier Luigi Buttigieg, Neil Davies, Raffaella Casotti, and Astrid Fischer. "The Ocean Biomolecular Observing Network (OBON)." Marine Technology Society Journal 56, no. 3 (June 8, 2022): 106–7. http://dx.doi.org/10.4031/mtsj.56.3.20.

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Abstract Ocean life—from viruses to whales—is built from “biomolecules.” Biomolecules such as DNA infuse each drop of ocean water, grain of sediment, and breath of ocean air. The Ocean Biomolecular Observing Network (OBON) is developing a global collaboration that will allow science and society to understand ocean life like never before. The program will transform how we sense, harvest, protect, and manage ocean life using molecular techniques, as it faces multiple stresses including pollution, habitat loss, and climate change. It will also help communities detect biological hazards such as harmful algal blooms and pathogens, and be a key component of next-generation ocean observing systems. OBON will encourage continuous standardization and intercalibration of methods and data interoperability to help enhance and future-proof capabilities. OBON's objectives are: 1) to build a coastal-to-open ocean multi-omics biodiversity observing system; 2) to develop and transfer capacity between partners; 3) to enhance marine ecosystem digitization and modelling and 4) to coordinate action on pressing scientific, management, and policy questions.
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Yokokawa, R., S. Takeuchi, T. Kon, M. Nishiura, R. Ohkura, M. Edamatsu, K. Sutoh, and H. Fujita. "Hybrid Nanotransport System by Biomolecular Linear Motors." Journal of Microelectromechanical Systems 13, no. 4 (August 2004): 612–19. http://dx.doi.org/10.1109/jmems.2004.832193.

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Ishii, Takahiro, Mitsunori Ikeguchi, Toshihiro Yamada, and Junta Doi. "Development of interactive biomolecular graphics system LIVE." Journal of Molecular Graphics 10, no. 1 (March 1992): 48–49. http://dx.doi.org/10.1016/0263-7855(92)80026-a.

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Xuan, G., S. Ghosh, S. Kim, P.-C. Lv, T. Buma, B. Weng, K. Barner, and J. Kolodzey. "TERAHERTZ SENSING OF MATERIALS." International Journal of High Speed Electronics and Systems 17, no. 01 (March 2007): 121–26. http://dx.doi.org/10.1142/s0129156407004333.

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Biomolecules such as DNA and proteins exhibit a wealth of modes in the Terahertz (THz) range from the rotational, vibrational and stretching modes of biomolecules. Many materials such as drywall that are opaque to human eyes are transparent to THz. Therefore, it can be used as a powerful tool for biomolecular sensing, biomedical analysis and through-the-wall imaging. Experiments were carried out to study the absorption of various materials including DNA and see-through imaging of drywall using FTIR spectrometer and Time Domain Spectroscopy (TDS) system.
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David A Dawson and Clare P Persad. "Targeting the endocannabinoid system in the treatment of addiction disorders." GSC Biological and Pharmaceutical Sciences 19, no. 2 (May 30, 2022): 064–74. http://dx.doi.org/10.30574/gscbps.2022.19.2.0175.

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This disquisition provides historical context illustrating the psychosocial, political, and bureaucratic barriers to applying a biomolecular approach to substance use disorders, focusing on what are arguably the most stigmatized molecules in America. It provides a biomolecular treatment strategy designed to mitigate multiple types of addiction by influencing the dopamine and serotonin neurotransmitters’ activity through phytocannabinoid supplementation of the endocannabinoid system and proposes a strategy for circumventing the bureaucratic obstacles.
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Dissertations / Theses on the topic "Biomolecular system"

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Rana, Sunil Kumar. "An electrostatically cantilever based biomolecular force measurement system." Thesis, University of Newcastle Upon Tyne, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.533689.

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Börjesson, Ulf Börjesson Ulf Erik. "Electrostatic interactions in computer simulations of biomolecular systems : influence of system size, solvation, and titration /." [S.l.] : [s.n.], 2004. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=15454.

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Wallbing, Linus. "Characterization of heterogeneity of biomolecular interactions using 3rd generation biosensor." Thesis, KTH, Skolan för kemivetenskap (CHE), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-215130.

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A new tool for kinetic evaluation of kinetic rate constants is enabled by a 3rd generation biosensor. The tool is developed to meet the need of reliably experimental information and communication between pharmaceutical companies and regulatory agencies to increase the productivity and decrease the associated risks. Too obtain the necessary competences and resources for this, a project consisting of Attana AB, AstraZeneca AB, Waters Nordic AB and Karlstad University was established. The main aim of the project is to achieve a comprehension understanding of interactions of different character e.g. fast and slow kinetics. This report concerns a fast interaction system. By analyzing a parathyroid hormone system using standard biosensor assays and single cycle kinetics with Attana Cell™ 200 instruments the fast interaction was characterized. The experimental data was analyzed using standard kinetic evaluation and an adaptive interaction distribution algorithm. The latter tool is developed at Karlstad university in order to describe the heterogeneity of interactions. The idea is to use the heterogeneity information as a decision support in drug development. A sub aim was to investigate the feasibility of the single cycle kinetic assays compared to the standard biosensors assays. The results shows a decrease of experimental time by 70% for homogene interaction and the protocol enables assay without or with less regeneration.
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Barroso, Camila Ercolini. "Aspectos quantitativo e biomolecular da vascularização do timo em gatos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-13112013-180616/.

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O sistema linfoide é composto de órgãos linfoides primários e secundários. O timo é um órgão linfoide primário responsável pela maturação, diferenciação e seleção da linhagem linfocitária do tipo T que é responsavel pela imunidade celular do individuo. Para cumprir estas funções, o timo possui uma disposição peculiar das suas células epiteliais morfologicamente distintas e de suas estruturas vasculares. Seus vasos sanguíneos possuem um papel na oxigenação tecidual e no processo de migração das células precursoras de linfócitos T para o interior do parênquima tímico e por isso apresentam uma arquitetura típica caracterizada por vasos de grande calibre, localizados na junção cortico-medular e uma fina rede de ramos e anastomoses que se estendem para o córtex. Este processo de estruturação e arquitetura vascular ainda possui sua base molecular desconhecida, assim como os mecanismos que provocam a involução do órgão. O VEGF é um fator angiogênico que atua na formação vascular e na modulação de funções relacionadas à vascularização, sendo um importante marcador da angiogênese. A fim de se melhor compreender o comportamento vascular na formação e involução tímica, propôs-se avaliar a expressão gênica e proteica deste fator durante fases de desenvolvimento e involução do órgão, além da quantificação da vascularização do timo pela técnica estereológica, análise do parênquima tímico pela técnica de microscopia eletrônica de varredura e análise dos tipos celulares presentes em cada estágio etário. Para tal utilizou-se amostras de timo de gato em quatro estágios de desenvolvimento fetal (35, 45, 55, 65), e dois estágios pós-natal (6 meses e 1 ano) para a realização da imuno-histoquímica, PCR em tempo real e MEV,e para a técnica estereológica 2 estágios pós-natal (6 meses e 1 ano). Na microscopia eletrônica de varredura foram observados os timócitos de diferentes tamanhos, em estágios de maturação distintos. As proteinas do VEGF-A e dos receptores Fit-1 e KDR foram identificadas no timo de gatos em todas as fases do desenvolvimento foram localizadas no citoplasma de células epiteliais e no interior dos corpúsculos tímicos. A expressão do mRNA no período de 1 ano de idade a expressão do mRNA do VEGF e seus receptores tem um aumento significativo, coincidindo com a diminuição do Nvasc e do Nv(vasc) podendo causar um estado de hipóxia no órgão levando a um aumento compensatório de sistema VEGF. A curva de crescimento vascular obedece a um padrão de desenvolvimento e involuçãio do órgão.
The lymphoid system is composed by primary and secondary lymphoid organs. The thymus is a primary lymphoid organ responsible for maturation, differentiation and selection of the lymphoid T cell lineage that is responsible for cellular immunity. To accomplish these functions has a peculiar arrangement with morphologically distinct epithelial cells and vascular structures. The blood vessels have a role in tissue oxygentation and the migration of T cells into the thymic parenchyma, therefore they presents large vessels in cortico-medullary junction and a fine network branches to the cortex. This process has its molecular basis unknown as well as the involution process of the thymus. VEGF is an angiogenic factor that plays a role in the formation and modulation of vascular functions, being an important marker of angiogenesis. We proposed to evaluate the gene and protein of VEGF during the thymus development and involution, stereological quantification and scanning electronic microscopy. Samples of cat´s thymus from 35, 45, 55, 65 days of development and 6 months and 1 year of age. In scanning electronic microscopy different stages maturation thymocytes were observed. Protein expression of VEGF and its receptors were identified in all development stages in epithelial cells, endothelial cells and thymic corpuscles. The VEGF mRNA expression and its receptors in 1 year old animals was significantly increased, coinciding with the decreasing Nvasc and the Nv(vasc) causing a hypoxic condition in the thymus resulting in a compensatory increase of VEGF system. The vascular growth curve follows a pattern of development and involution of the organ.
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Börjesson, Ulf [Verfasser]. "Electrostatic interactions in computer simulations of biomolecular systems: influence of system size, solvation, and titration / Ulf Börjesson." Aachen : Shaker, 2004. http://d-nb.info/1170529933/34.

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Alper, Joshua Daniel. "Physical and practical limits of a biomolecular control system using nanoparticles and electromagnetic field irradiation." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/57551.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2010.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student-submitted PDF version of thesis.
Includes bibliographical references (p. 195-210).
Many nanometer length scale engineering applications of mechanics and biology including computation, sensing, self-assembly, transport, and molecular machine design take advantage of natural biomolecular machinery. Further development of these technologies requires direct, external biomolecular control. This thesis proposes a simple control technique: a biomolecular \on/o" activity switch in which metallic nanoparticles (NPs) are conjugated to target biomolecules and irradiated with an electromagnetic field. Due to their unique physical properties, the NPs specifically absorb the field's energy. They convert the energy to heat, and then they transport it to the conjugated target biomolecules. The heat affects a change in the targeted biomolecules, selectively actuating their activity. This thesis is on the mechanisms by which both ultrafast pulsed laser irradiation and radio frequency alternating magnetic fields (RFMFs) can be used as energy sources for the proposed biomolecular activity switch. The thesis reports on the quantification of a fs-pulsed laser triggered release mechanism that actuates activity of the molecules released from NPs. The release mechanism is governed by NP surface chemistry. The operating window for the critical parameters governing release including NP properties and laser fluence is defined. The thesis also reports on transmission pump-probe experiments that show the thermal interface conductance (G) of NPs is critical to nanoscale thermal transport, and that G is a strong function of the NP's surface chemistry. The thesis concludes that an ultrafast pulsed laser actuated biomolecular activity switch is feasible if the critical parameters are carefully controlled. However, experimental studies revealed that using RFMFs in this biomolecular activity switching technique is not feasible. These results are validated by theoretical and analytical studies of nanoscale heat generation and transport in the system. The results presented in this thesis have implications on the design of the biomolecular activity switch, and many of the results are also applicable to other nanoscale thermal applications including hyperthermia cancer treatments and triggered drug delivery techniques.
by Joshua Daniel Alper.
Ph.D.
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Abdullah, Laila. "Identification of biomolecular pathways associated with the central nervous system based symptoms of Gulf War Illness." Thesis, Open University, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.580127.

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The clinical profile of Gulf War Illness (GWI) is characterized by the presence of the central nervous systems (CNS) symptoms, which include memory impairment, anxiety, widespread pain and motor problems. Now, even twenty years later, veterans with GWI continue to suffer from these persistent symptoms. Currently, there is no treatment available for treating GWI, which is largely due to the complexity of the clinical presentation of this illness and the heterogeneity of OW exposures. The main goals of this thesis were to develop and characterize GW agent exposure mouse models that recapitulate the CNS symptoms of GWI and to identify the underlying aberrant biological pathways. Three major objectives were undertaken to accomplish these goals: (1) Two mouse models of OW-agent exposure were developed using combination of the anti-nerve gas treatment pyridostigmine bromide (PB), pesticide (permethrin), an insect repellent (N,N-Diethyl-meta-toluamide) and stress. Neurobehavioral studies show that combined exposure to GW agents produced anxiety and sensorimotor deficits in one mouse model and anxiety and cognitive impairment in the other. Neuropathological studies showed a presence of astrogliosis in both models. (2) Exploratory proteomic studies suggested that lipid-metabolism and immune/inflammation were associated with GW-agent exposure. (3) As lipid dysfunction is upstream of the inflammatory pathways, a lipidomics approach was used to identify the OW-agent exposure dependent lipid profiles. Lipid profiles of mouse models of OW-agent exposure were compared with those of other neurological conditions to identify profiles that were unique to GW-agent exposure. Lipid profiles were interrogated to identify lipid-metabolism pathways that may be amenable to therapeutic targeting. Studies described in this thesis provide novel insight into the pathobiology of GWI and suggest that pathways involved in phosphatidylcholine metabolism might be of therapeutic value in treating the CNS symptoms of GWI.
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Edgerton, Alexander James. "Design and Testing of a Hydrogel-Based Droplet Interface Lipid Bilayer Array System." Thesis, Virginia Tech, 2015. http://hdl.handle.net/10919/56894.

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The research presented in this thesis includes the development of designs, materials, and fabrication processes and the results of characterization experiments for a meso-scale hydrogel-based lipid bilayer array system. Two design concepts are investigated as methods for forming Droplet Interface Bilayer (DIB) arrays. Both concepts use a base of patterned silver with Ag/AgCl electrodes patterned onto a flat polymer substrate. In one technique, photopolymerizable hydrogel is cured through a mask to form an array of individual hydrogels on top of the patterned electrodes. The other technique introduces a second type of polymer substrate that physically supports an array of hydrogels using a set of microchannels. This second substrate is fitted onto the first to contact the hydrogels to the electrodes. The hydrogels are used to support and shape droplets of water containing phospholipids, which self-assemble at the surface of the droplet when submerged in oil. Two opposing substrates can then be pushed together, and a bilayer will form at the point where each pair of monolayers come into contact. The photopatterning technique is used to produce small arrays of hydrogels on top of a simple electrode pattern. Systems utilizing the microchannel substrate are used to create mesoscale hydrogel arrays of up to 3x3 that maintained a low resistance (~50-150 kΩ) connection to the substrate. Up to three bilayers are formed simultaneously and verified through visual observation and by recording the current response behavior. Arrays of varying sizes and dimensions and with different electrode patterns can be produced quickly and inexpensively using basic laboratory techniques. The designs and fabrication processes for both types of arrays are created with an eye toward future development of similar systems at the microscale.
Master of Science
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DIMONTE, ALICE. "Nanogap structures for molecular electronics and biosensing." Doctoral thesis, Politecnico di Torino, 2013. http://hdl.handle.net/11583/2506146.

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Molecular transport characterization is an active part of the research field in nanotechnology. In this interesting branch the self-assembly approach is highly exploited; it consists in spontaneous formation of highly ordered monolayers on various substrate surfaces. Self-assembled monolayers (SAMs) have found their applications in various areas, such as nanoelectronics, surface engineering, biosensing, etc. An important area in biosensing is the electrochemical detection, that enables sensing of dierent biomarkers with an important role, for many dierent applications in biomedical diagnostics or in monitoring of biological systems. Various test structures have been developed in order to carry out characterizations of self-assembled molecules, and numerous reports have been published in the past several years on the transport characteristics. This thesis' purpose is the single protein biomolecular sensing, that could become the starting point for monitoring drugs, developing clean energy systems, realizing bio-opto-electronic transistors... The possibility to cover so many fields is related to the kind of proteins, molecules, bioelements that will be inserted inside sensors. Biomolecular sensing has to be thought in order to reach a result with the better compromise between instrumentation versatility and measurements precision. The main underlying idea is to use single molecules as active elements in nano-devices. As a consequence, the proper realization of a molecule-electrode contact is a crucial issue. What is needed by author is something versatile, precize, cheap, at single molecule level and able to record measurements in few time in order to do statistical characterizations. The final goal of this work is a platform system adapt for both industry and research field. Electrical nanogap devices are the main character of this work. They have proven good performances as element for detecting small quantities of biomolecules, allowing direct transduction of biomolecular signals into useful electrical ones such as resistance/impedance, capacitance/dielectric, or field effect. Nanogaps are now one of the most busy area of research in the nanotechnology world. Moreover, these structures do not require feedback to maintain the mutual arrangement (comparing with conducting tip AFM) and are less stochastic with respect to electrochemical cells. Several techniques can be applied to nanogap fabrication: mechanically broken or positioned junctions, nano-scale lithography by Synchrotron radiation sources, electrochemical deposition and etching, and electromigration. None of these techniques is presently able to give precise control as to thefinal gap size. In this thesis the electromigration approach has been choosen, because of several useful characteristics. It is cost eective, because of the relatively low complexity of the required equipment. It can be embedded into a lab-on-chip system, thus exploiting the possibility to tailor the gap formation process by means of a digital loop control system. To this end, it just requires a conventional microchip fabrication process. It allows the parallelization with a smart packaging through which it is possible to produce more probes at the same time and perform many measurements in contemporary. The employment of nanogaps, as an instrumentation for the molecular charac- terization, has also some issues that have to be considered in order to obtain useful measurements. To characterize molecules the leakedge must be not higher than some pA to avoid the noise overcome the signal. Nanogap platform is perfect for molecular electronics. The experiments have been developed in dry way, as a consequence the solutions were evaporated before the measurement starting. This brought several problems cause biochemical analysis requires liquid solution in order to avoid an untimely death of the bio-elements tha has to be characterized. Considering a future developement, an improvement is necessary in terms of a system able to work with salty solutions without damaging the microchip's probes. Therefore it is a necessary a set-up allowing the anchorage of a microfluidic part. At the same time it is necessary to keep in mind that the presence of a new system has to not overcome the molecule signal, maintaining the leakedge under some tens of pA.
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Brampton, Christopher. "Forces in biomolecular systems." Thesis, University of Nottingham, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429077.

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Books on the topic "Biomolecular system"

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1937-, Vasilescu D., and UNESCO International Conference on "Water and Ion in Biomolecular Systems" (5th : 1989 : Parc Valrose Scientific Campus of Nice-Sophia Antipolis University), eds. Water and ions in biomolecular systems: Proceedings of the 5th UNESCO International Conference. Basel: Birkhäuser Verlag, 1990.

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van Gunsteren, Wilfred F., Paul K. Weiner, and Anthony J. Wilkinson, eds. Computer Simulation of Biomolecular Systems. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-017-1120-3.

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García Gómez-Tejedor, Gustavo, and Martina Christina Fuss, eds. Radiation Damage in Biomolecular Systems. Dordrecht: Springer Netherlands, 2012. http://dx.doi.org/10.1007/978-94-007-2564-5.

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Christina, Fuss Martina, and SpringerLink (Online service), eds. Radiation Damage in Biomolecular Systems. Dordrecht: Springer Netherlands, 2012.

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Joint Greek-Italian Meeting on Chemistry and Biological Systems and Molecular Chemical Engineering (2nd 1992 Cetraro, Italy). Properties and chemistry of biomolecular systems: Proceedings of the Second Joint Greek-Italian Meeting on Chemistry and Biological Systems and Molecular Chemical Engineering, Cetraro, Italy, October 1992. Dordrecht: Kluwer Academic Publishers, 1994.

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Rizzarelli, E., and T. Theophanides, eds. Chemistry and Properties of Biomolecular Systems. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3620-4.

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Russo, N., J. Anastassopoulou, and G. Barone, eds. Properties and Chemistry of Biomolecular Systems. Dordrecht: Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0822-5.

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Vasilescu, D., J. Jaz, L. Packer, and B. Pullman, eds. Water and Ions in Biomolecular Systems. Basel: Birkhäuser Basel, 1990. http://dx.doi.org/10.1007/978-3-0348-7253-9.

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Ryabov, Artem. Stochastic Dynamics and Energetics of Biomolecular Systems. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-27188-0.

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1938-, Beveridge David L., Jorgensen William L, and New York Academy of Sciences., eds. Computer simulation of chemical and biomolecular systems. New York, N.Y: New York Academy of Sciences, 1986.

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Book chapters on the topic "Biomolecular system"

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May, Elebeoba E. "Circuit-Based Models of Biomolecular System Dynamics." In Simulation and Verification of Electronic and Biological Systems, 137–56. Dordrecht: Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-0149-6_7.

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Riaz, Muhammad, Muhammad Zia-Ul-Haq, and Bashar Saad. "Anthocyanins Effects on Carcinogenesis, Immune System and the Central Nervous System." In Anthocyanins and Human Health: Biomolecular and therapeutic aspects, 125–38. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26456-1_9.

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Halm, Andreas, Eva Eggeling, and Dieter W. Fellner. "Embedding Biomolecular Information in a Scene Graph System." In Mathematics and Visualization, 249–64. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-21608-4_14.

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Chiu, S. W., M. Clark, V. Balaji, S. Subramaniam, H. L. Scott, and E. Jakobsson. "Simulation of a Fluid Phase Lipid Bilayer Membrane: Incorporation of the Surface Tension into System Boundary Conditions." In Modelling of Biomolecular Structures and Mechanisms, 59–67. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0497-5_5.

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Haymond, Shannon. "System Performance Monitoring in Clinical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)." In Clinical Applications of Mass Spectrometry in Biomolecular Analysis, 13–25. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2565-1_2.

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Seese, A., and P. P. Mager. "Simple Feedback System Used to Model Biomolecular Reactions in Drug-Receptor Populations." In Thermodynamics and Regulation of Biological Processes, edited by Ingolf Lamprecht and A. I. Zotin, 213–28. Berlin, Boston: De Gruyter, 1985. http://dx.doi.org/10.1515/9783110861198-016.

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Tien, H. Ti. "The New Bilayer Lipid Membrane System: Prospects for Applications in Biomolecular Electronic Devices." In Topics in Molecular Organization and Engineering, 167–73. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3392-0_19.

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Solov’yov, Ilia A., Andrey V. Korol, and Andrey V. Solov’yov. "Biomolecular Systems." In Multiscale Modeling of Complex Molecular Structure and Dynamics with MBN Explorer, 171–98. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56087-8_5.

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Keya, Jakia Jannat, Kentaro Kayano, Arif Md Rashedul Kabir, and Akira Kakugo. "Integration of Soft Actuators Based on a Biomolecular Motor System to Develop Artificial Machines." In Soft Actuators, 691–709. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6850-9_39.

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Andrusiak, Matthew G., and Yishi Jin. "In Vivo Analysis of a Biomolecular Condensate in the Nervous System of C. elegans." In Methods in Molecular Biology, 575–93. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2597-2_35.

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Conference papers on the topic "Biomolecular system"

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Hossain, Md Razuan, Joseph S. Najem, Tauhidur Rahman, and Md Sakib Hasan. "Reservoir Computing System using Biomolecular Memristor." In 2021 IEEE 21st International Conference on Nanotechnology (NANO). IEEE, 2021. http://dx.doi.org/10.1109/nano51122.2021.9514305.

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Inoue, Daisuke, Arif Rashedul Kabir, and Akira Kakugo. "Intelligence of reconstructed biomolecular motor system." In 9th EAI International Conference on Bio-inspired Information and Communications Technologies (formerly BIONETICS). ACM, 2016. http://dx.doi.org/10.4108/eai.3-12-2015.2262588.

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Nguyen, Mary-Anne, and Andy Sarles. "Microfabrication for Packaged Biomolecular Unit Cells." In ASME 2013 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/smasis2013-3068.

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This paper focuses on developing a closed fluidic environment for packaging biomolecular unit cells, which consists of a synthetic lipid bilayer and other biomolecules contained in a near solid-state material with two regions that contain hydrophobic oil (i.e. nonpolar solvent) surrounding aqueous droplets. This research provides a stepping-stone towards an autonomic biomolecular material system, whereby a packaged system will allow for precise droplet interface bilayer (DIB) formation without the interference of outside contamination for long-term applications. Also, substrate materials need to maintain droplets and preserve the self-assembly and stimuli-responsive properties of biomolecules within the unit cell. A critical feature of an encapsulating material is that it does not absorb either of the liquid phases required to form DIBs. Oil depletion tests within sealed, polymeric substrates show that polydimethylsiloxane (PDMS) absorbs full volume of injected hexadecane in approximately 27 hours. However, polyurethane substrates maintain the original amount of oil injected even after several weeks. Bilayer lifetime is also monitored within an environment in which the oil is also depleting. The results of this test show the longevity of a DIB to be shorter than oil lifetime. The lipid-encased droplets disconnect after approximately 10 hours, when there is only approximately <60% amount of oil present. In addition, an initial microfluidic substrate is designed such that a single T-junction intersection can be used to form monodisperse droplets within a primary oil-filled channel and a downstream increase in channel width can be used to connect droplets to form DIBs.
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Najem, Joseph, Alex Edgerton, and Donald J. Leo. "Biomolecular hydrogel-based lipid bilayer array system." In SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, edited by Raúl J. Martín-Palma and Akhlesh Lakhtakia. SPIE, 2013. http://dx.doi.org/10.1117/12.2010695.

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Foo, Mathias, Rucha Sawlekar, Jongmin Kim, Declan G. Bates, Guy-Bart Stan, and Vishwesh Kulkarni. "Biomolecular implementation of nonlinear system theoretic operators." In 2016 European Control Conference (ECC). IEEE, 2016. http://dx.doi.org/10.1109/ecc.2016.7810556.

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Wang, Yi, and Kapil Pant. "System-Level Modeling of Surface-Immobilized Biomolecular Concentration Gradient Generation." In ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer. ASMEDC, 2009. http://dx.doi.org/10.1115/mnhmt2009-18360.

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This paper presents a system-level modeling methodology for microfluidic surface-immobilized biomolecular concentration gradient generators (CGGs). The generator is broken down into a system of elemental microfluidic components with relatively simple geometries and functionality. Parameterized models for such components are developed, which hold for general biomolecular concentration profiles and arbitrary flow ratios at the component interface; hence, they are valid for a broad category of CGGs that rely on various operating mechanisms. The component models are then linked through an appropriate set of parameters at the interfaces to construct a system-level, network representation of the entire generator for simulation. The system model is extensively verified against experimental data reported in the literature. The model results are found to be in excellent agreement, and can be applied to accurately capture the overall effects of network geometry, biomolecular properties, operating parameters (e.g., flow rates and initial biomolecular concentration) on the generation of biomolecular gradients on the surfaces. The model also demonstrates salient computational efficiency (seconds of execution time) and can be used to guide fast, reliable, system-level design of CGGs and associated bioassays.
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Tamanaha, C. R., S. P. Mulvaney, and J. C. Rife. "Evolution of a magnetic-based biomolecular detection system." In 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2009. http://dx.doi.org/10.1109/iembs.2009.5332482.

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Persson, Petter Bivall, Matthew D. Cooper, Lena A. E. Tibell, Shaaron Ainsworth, Anders Ynnerman, and Bengt-Harald Jonsson. "Designing and Evaluating a Haptic System for Biomolecular Education." In 2007 IEEE Virtual Reality Conference. IEEE, 2007. http://dx.doi.org/10.1109/vr.2007.352478.

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Samaniego, Christian Cuba, Nicholas A. Delateur, Giulia Giordano, and Elisa Franco. "Biomolecular stabilisation near the unstable equilibrium of a biological system." In 2019 IEEE 58th Conference on Decision and Control (CDC). IEEE, 2019. http://dx.doi.org/10.1109/cdc40024.2019.9029433.

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Nunes, Rafael, Paulo J. Costa, Diogo Vila-Viçosa, and Miguel Machuqueiro. "T4 Lysozyme/Halobenzene: A Test System for Modeling Biomolecular Halogen Bonds." In MOL2NET 2017, International Conference on Multidisciplinary Sciences, 3rd edition. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/mol2net-03-05075.

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Reports on the topic "Biomolecular system"

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Lundgren, Cynthia A., David Baker, Barry Bruce, Maggie Hurley, Amy K. Manocchi, Scott Pendley, and James Sumner. Hydrogen Production from Water by Photosynthesis System I for Use as Fuel in Energy Conversion Devices (a.k.a. Understanding Photosystem I as a Biomolecular Reactor for Energy Conversion). Fort Belvoir, VA: Defense Technical Information Center, April 2014. http://dx.doi.org/10.21236/ada601589.

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Doktycz, M. J. Dual Manifold System for Arraying Biomolecules. Office of Scientific and Technical Information (OSTI), April 2001. http://dx.doi.org/10.2172/814531.

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Beebe, David J. An Advanced Platform for Biomolecular Detection and Analysis Systems. Fort Belvoir, VA: Defense Technical Information Center, February 2005. http://dx.doi.org/10.21236/ada432950.

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Reichert, D. E., and P. J. A. Kenis. Microfluidic Radiometal Labeling Systems for Biomolecules. Office of Scientific and Technical Information (OSTI), December 2011. http://dx.doi.org/10.2172/1032377.

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Bachand, George David, and Amanda Carroll-Portillo. Engineering intracellular active transport systems as in vivo biomolecular tools. Office of Scientific and Technical Information (OSTI), November 2006. http://dx.doi.org/10.2172/899371.

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Clark, Douglas S. Performance-Enhancing Biomolecular Treatment Strategies for Naval Graywater Filtration Systems. Fort Belvoir, VA: Defense Technical Information Center, March 2002. http://dx.doi.org/10.21236/ada399945.

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Doktycz, M. J. CRADA Final Report-Dual Manifold System for Arraying Biomolecules. Office of Scientific and Technical Information (OSTI), May 2001. http://dx.doi.org/10.2172/814372.

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Waldo, Geoffrey S. UTS, THE UNIVERSAL TAGGING SYSTEM FOR QUANTITATIVE LABELING OF BIOMOLECULES. Office of Scientific and Technical Information (OSTI), January 2020. http://dx.doi.org/10.2172/1595636.

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Hummer, G., A. E. Garcia, and D. M. Soumpasis. Potential-of-mean-force description of ionic interactions and structural hydration in biomolecular systems. Office of Scientific and Technical Information (OSTI), October 1994. http://dx.doi.org/10.2172/10186924.

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Moore, Jeff, Hassan Aref, Ron Adrian, Deborah Leckband, and David J. Beebe. Engineering Solutions for Robust and Efficient Microfluidic Biomolecular Systems: Mixing, Fabrication, Diagnostics, Modeling, Antifouling and Functional Materials. Fort Belvoir, VA: Defense Technical Information Center, September 2002. http://dx.doi.org/10.21236/ada411413.

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