Academic literature on the topic 'Biomolecular Sensors'
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Journal articles on the topic "Biomolecular Sensors"
Miao, Yanming, Jinzhi Lv, Yan Li, and Guiqin Yan. "Construction of biomolecular sensors based on quantum dots." RSC Advances 6, no. 110 (2016): 109009–22. http://dx.doi.org/10.1039/c6ra20499f.
Full textSun, Nan, Yong Liu, Ling Qin, Hakho Lee, Ralph Weissleder, and Donhee Ham. "Small NMR biomolecular sensors." Solid-State Electronics 84 (June 2013): 13–21. http://dx.doi.org/10.1016/j.sse.2013.02.005.
Full textKelley, Shana. "Biomolecular Sensors: Benchmarking Basics." ACS Sensors 1, no. 12 (December 23, 2016): 1380. http://dx.doi.org/10.1021/acssensors.6b00775.
Full textVACIC, ALEKSANDAR, and MARK A. REED. "BIOMOLECULAR FIELD EFFECT SENSORS (BIOFETS): FROM QUALITATIVE SENSING TO MULTIPLEXING, CALIBRATION AND QUANTITATIVE DETECTION FROM WHOLE BLOOD." International Journal of High Speed Electronics and Systems 21, no. 01 (March 2012): 1250004. http://dx.doi.org/10.1142/s0129156412500048.
Full textLiu, Xiyuan, and Peter B. Lillehoj. "Embroidered electrochemical sensors for biomolecular detection." Lab on a Chip 16, no. 11 (2016): 2093–98. http://dx.doi.org/10.1039/c6lc00307a.
Full textDensmore, A., D. X. Xu, S. Janz, P. Waldron, J. Lapointe, T. Mischki, G. Lopinski, A. Delâge, J. H. Schmid, and P. Cheben. "Sensitive Label-Free Biomolecular Detection Using Thin Silicon Waveguides." Advances in Optical Technologies 2008 (June 16, 2008): 1–9. http://dx.doi.org/10.1155/2008/725967.
Full textChong, Chen, Hongxia Liu, Shulong Wang, Shupeng Chen, and Haiwu Xie. "Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor." Micromachines 12, no. 1 (December 27, 2020): 19. http://dx.doi.org/10.3390/mi12010019.
Full textStern, Eric, Aleksandar Vacic, and Mark A. Reed. "Semiconducting Nanowire Field-Effect Transistor Biomolecular Sensors." IEEE Transactions on Electron Devices 55, no. 11 (November 2008): 3119–30. http://dx.doi.org/10.1109/ted.2008.2005168.
Full textTian, Fang, Karolyn M. Hansen, Thomas L. Ferrell, Thomas Thundat, and Douglas C. Hansen. "Dynamic Microcantilever Sensors for Discerning Biomolecular Interactions." Analytical Chemistry 77, no. 6 (March 2005): 1601–6. http://dx.doi.org/10.1021/ac048602e.
Full textDatar, Ram, Seonghwan Kim, Sangmin Jeon, Peter Hesketh, Scott Manalis, Anja Boisen, and Thomas Thundat. "Cantilever Sensors: Nanomechanical Tools for Diagnostics." MRS Bulletin 34, no. 6 (June 2009): 449–54. http://dx.doi.org/10.1557/mrs2009.121.
Full textDissertations / Theses on the topic "Biomolecular Sensors"
Marti, Villalba Maria. "Biomolecular engineered sensors for diagnostic applications." Thesis, Nottingham Trent University, 2009. http://irep.ntu.ac.uk/id/eprint/363/.
Full textCooper, Emily Barbara 1977. "Silicon field-effect sensors for biomolecular assays." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/87450.
Full textIncludes bibliographical references.
System-level understanding of biological processes requires the development of novel biosensors capable of quantitative, real-time readout of molecular interactions. Label-free detection methods can minimize costs in time and resources by obviating preparatory steps necessary with label-based methods. They may further be valuable for monitoring biomolecular systems which are difficult or impossible to tag, or for which reporter molecules interfere with biological function. Field-effect sensing is a method of directly sensing intrinsic electrical charge associated with biomolecules without the need for reporter molecules. Microfabrication of field-effect biosensors enables their integration in compact microanalytical systems, as well as the potential to be scaled down in size and up in number. Applying field-effect sensing to the detection and real-time monitoring of specific molecular interactions has long been of interest for protein and nucleic acids analysis. However, these applications are inhibited by serious practical limitations imposed by charge screening in solution. The development of effective measurement techniques requires inquiry into aspects of device engineering, surface chemistry, and buffer conditions. This thesis describes a body of experimental work that investigates the feasibility of label-free analysis of biomolecular interactions by field-effect. This work begins with the microfabrication of field-effect sensors with extremely thin gate oxide, which enables improved surface potential resolution over previously reported sensors.
(cont.) The performance of these sensors has been characterized in terms of drift, noise, and leakage. To better understand the applicability of these sensors, we have characterized the sensors' response to pH, adsorption of polyelectrolyte multilayers, and high-affinity molecular recognition over a range of buffer conditions. Direct, label-free detection of DNA hybridization was accomplished by combining the high-resolution sensors, with enabling surface chemistry, and a differential readout technique. Finally, we explore the lateral scaling limits of potentiometry by applying a novel nanolithographic technique to the fabrication of a single electron transistor that demonstrates Coulomb oscillations at room temperature.
by Emily Barbara Cooper.
Ph.D.
Anderson, Henrik. "Development of Electroacoustic Sensors for Biomolecular Interaction Analysis." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-107211.
Full textRusso, Peter R. (Peter Raphael) 1980. "Integrated silicon field-effect sensors and microfluidics for biomolecular detection." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/17977.
Full textIncludes bibliographical references (p. 52-53).
Microfabricated silicon field-effect sensors with integrated poly(dimethylsiloxane) microfluidic channels have been demonstrated. These devices are designed for the label-free detection and recognition of specific biomolecules such as DNA. Label-free methods eliminate the time-consuming and costly step of tagging molecules with radioactive or fluorescent markers prior to detection. The devices presented here are sensitive to the intrinsic charge of the target molecules, which modulates the width of the carrier-depleted region of a lightly-doped silicon sensor. The variable depletion capacitance is precisely measured, indicating changes in sensor surface potential of less than 30[micro]V. The integrated microfluidic channels enable the delivery of small (nanoliter-scale) amounts of fluid directly to the sensors. Capacitance-voltage curves were recorded using phosphate buffered saline (PBS) as the test electrolyte; a maximum slope of 44pF/V was measured in depletion. pH sensitivity was also demonstrated using modified PBS solutions. A device with dual 80x80Om sensors yielded a response of 40mV/decade, referenced to the fluid electrode. A device with dual 50x50[micro]m sensors yielded a response of 12mV/decade, referenced to the sensors.
by Peter R. Russo.
M.Eng.
Zhang, Xiaojuan. "INVESTIGATION OF BIOMOLECULAR INTERACTIONS FOR DEVELOPMENT OF SENSORS AND DIAGNOSTICS." VCU Scholars Compass, 2011. http://scholarscompass.vcu.edu/etd/294.
Full textTosolini, Giordano. "Force sensors based on piezoresistive and MOSFET cantilevers for biomolecular sensing." Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/131408.
Full textBiorecognition processes between receptors and their conjugate ligands are very important in biology. These biomolecules can build up very specific complexes displaying a variety of functions such as genome replication and transcription, enzymatic activity, immune response, cellular signaling, etc. The unambiguous one-to-one complementarity exhibited by these biological partners is widely exploited also in biotechnology to develop biosensors. Depending on the nature of the transduction signals, biosensors can be classified in optical, electrical and mechanical. Among mechanical biosensors, the microcantilevers play a prominent role. They have been used as stress or mass transducers in biomolecules detection for already more than a decade. The binding of molecules to their functionalized surface is detected by measuring either the deflection in static mode or the resonant frequency shift in dynamic mode. The deflection of the cantilever is converted optically by a laser and a photodetector in order to have the highest possible resolution. This limits the measurements in transparent liquids, the portability of the instrument and increases the complexity for multiplexing. The development of self-sensing cantilevers by integrating piezoresistors or metal-oxide-semiconductor field effect transistors (MOSFET) into the cantilever solves this issue. However, at the same time, this decreases the bending and frequency shift resolution due to the higher transducer noise. On the other hand, the detection of a single molecule can be attained measuring the unbinding force between two molecules of a complex pulling them apart, using the atomic force spectroscopy (AFS) measuring approach. This technique is based on the atomic force microscope (AFM). Despite the high force resolution, AFM has still not become an analytical instrument and it is mainly due to the complexity of the instrument and of its use. A biosensor based on AFS and on self-sensing cantilever would allow single molecule resolution, working in opaque fluids, easy multiplexing capability, and relatively easy integration in microfluidics cells. In this perspective, we worked to obtain self sensing-probes endowed with pN resolution and compatible with liquid media. Cantilevers based on single crystalline silicon have been modeled and the fabrication process has been optimized to improve the force sensitivity and to obtain high fabrication yield. At the same time we worked also on the modeling, development and fabrication of cantilevers with embedded MOSFET piezoresistive transducers. It turned out that the probes with integrated piezoresistor offer a more straightforward solution, but also the MOSFET cantilever can offer a good alternative. Alongside the force sensors fabrication, new high-throughput set-ups and techniques have been developed and optimized to measure the electrical and electromechanical characteristics of micro-electro-mechanical systems (MEMS) in a precise and reliable way. This was of key importance to correctly validate the new technological processes involved in production as well as characterize the final devices. After achieving very good sensor performances (resolution < 10 pN in liquid environment) with high production yield, we used the force probes to investigate the biorecognition processes in the avidin-biotin complex. For this purpose we integrated the sensor into a commercial AFM to take advantage of the high mechanical stability of this equipment and the highly reliable displacement of the piezo actuator. We detected the forces related to the avidin-biotin complex formation, highlighting the possibility of biomolecule label-free recognition in nearly physiological conditions and at single molecule resolution. Beside the very high sensitivity attained, the sensor can be used with no restrictions in opaque media; it can be easily integrated in microfluidic cells and it displays a high multiplexing potentiality. This result opens new perspectives in highly sensitive label free biomarkers detectors in nearly physiological conditions.
Weckman, Nicole Elizabeth. "Microfabricated acoustic sensors for the detection of biomolecules." Thesis, University of Cambridge, 2018. https://www.repository.cam.ac.uk/handle/1810/274899.
Full textDing, Shu Gu Li-Qun. "Aptamer encoded nanopores as single molecule sensors." Diss., Columbia, Mo. : University of Missouri--Columbia, 2008. http://hdl.handle.net/10355/5767.
Full textJanczak, Colleen. "Hybrid Nanoparticles for Enhanced Sensitivity in Biological Labeling and Biomolecular Sensing." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/202514.
Full textDe, la Rica Quesada Roberto. "New concepts for electrical detection of biomolecules." Doctoral thesis, Universitat Autònoma de Barcelona, 2007. http://hdl.handle.net/10803/3584.
Full textEn primer lloc, es presenta un nou tipus de transductor impedimetric (I). Es va escollir un disseny basat en dos electrodes interdigitats per dos motius principals. Primer, aquesta geometria permet monitoritzar tant la resistència como la constant dieléctrica d'una solució, la qual cosa fa dels electrodes interdigitats eines més versatils que altres tipus transductors. Segon, els electrodes presenten una curta penetració del camp electric, la qual cosa els fa mes sensibles als canvis que tenen lloc a prop de la seva superfície. Aquest fet permet monitoritzar canvis locals en les magnituds d'interés. Finalment, són apropiats no nomes per construir sensors sinó també actuadors. Aquesta geometria sembla ser útil en experiments de dielectroforesi. Una innovació introduïda en aquesta tesi es el material escollit per fabricar els electrodes: silici policristal-lí o polisilici. El polisilici pot ser facilment modificat per donar lloc a superficies amb particulars propietats químiques i físiques, fent d'aquest material un excel-lent candidat per a la manufactura de biosensors, comparable a altres aproximacions com la quemisorció de alcanotiols sobre electrodes d'or.
Els esmentats electrodes interdigitats es van fer servir per probar dos nous sistemes de transducció. Ambdues aproximacions comparteixen un tret comu: aprofiten la capacitat dels electrodes interdigitats per mesurar canvis local en les propietats elèctriques del medi on es troben submergits. En II, aquest fet és utilitzat per monitoritzar una reacció enzimàtica, i es mostra com la característica de mesura local en electrodes interdigitats dóna lloc a una detecció més sensible. A més, es demostra que aquesta aproximació es adequada per la detecció de proteïnes fent servir l'enzim com a marca en un immunoassaig. En III, els electrodes interdigitats actuen com a sensor i actuador. Com a actuador, els electrodes son capaços de concentrar esferes de làtex a la seva superficie. Com a transductors, la presencia de les micropartícules aïllants a la seva superficie dóna lloc a un canvi en la geometria de la cel-la, que pot ser detectat monitoritzant tant la resistència com la capacitat de la solucio. Aquest mode de funcionament es paral-lel al dels sensors magnetoresistius, i el principi de transduccio proposat es presenta com a una alternativa a ells.
Finalment, un quart treball es presenta en aquesta tesi (anex). Comparteix dues característiques en comú amb els treballs previs: el sustrat (silici) i una metodologia per la inmoblització de biomolecules (silanització). Les seves aplicacions son, però, diferents i cobreixen un rang més ampli d'aplicacions. En concret, una nova metodologia pel nanoestructurat de superfícies, de baix cost i fàcil disponibilitat és presentada. Es van aconseguir motius fets amb molècules de silà amb dimensions inferiors als 10 nm. En el marc de la biodetecció, aquesta nova tècnica per nanoestructurat superficial es propossa com a alternativa a la nanolitografia dip-pen per la manufactura de nanomatrius de biomolècules. Les petites dimensions dels motius obtinguts obren el cami per la consecució de nanomatrius d'una única molècula.
This work discusses different aspects related to the design of biosensors and biodetection systems. It describes the fabrication and characterization of particular electric transducers together with the development of new transduction systems and the finding of new methodologies for biomolecule nanoarray fabrication.
Firstly, a new type of impedimetric transducer is presented (I). A two-electrode interdigitated design was chosen, mainly for three reasons. First, this geometry allows the monitoring of both the resistivity and the dielectric constant of a solution, thus making interdigitated electrodes more versatile tools than other kind of transducers. Second, they present short electric field penetration depths, which make them more sensitive to changes occurring close to their surface. This fact enables the monitoring of local changes in the magnitudes of interest. Finally, they are suitable for constructing not only sensors but also actuators. This geometry appears to be useful in dielectrophoresis experiments. One innovation introduced in this thesis is the material chosen to fabricate the electrodes: polycrystalline silicon, also known as polysilicon. Polysilicon can be easily modified to render surfaces with distinct physical and chemical properties, thus making this material an excellent approach for biosensors manufacture, comparable to other approaches like alkanethiol chemisorption on gold electrodes.
The aforementioned interdigitated electrodes were used to test two new transduction principles. The two approaches share a common feature: they rely on the ability of interdigitated electrodes to measure local changes in the electrical properties of the medium where they are immersed. In II, this is used to monitor an enzymatic reaction, and it is shown that the characteristics of measuring local changes at interdigitated electrodes result in a more sensitive detection. Furthermore, the feasibility of this approach for protein detection is demonstrated by using the enzyme as a label for performing an immunoassay. In III, the interdigitated electrodes act both as a transducer and as an actuator. As an actuator, the electrodes are able to concentrate latex beads at their surface. As a transducer, the presence of the insulating microparticles at their surface results in a change in the geometry of the cell, that can be detected by monitoring either the resitance or the capacitance of the solution. Such device performance is parallel to that of magnetoresistive biosensors, and the proposed transduction principle is envisaged as a suitable alternative to them.
Finally, a fourth work is presented in this thesis (Annex). It shares two features in common with the previous works: the substrate (silicon) and a method for biomolecule immobilization (silanization). However, the applications are somehow different, and cover a wider range. Precisely, a new methodology for low cost, easily available nanopatterning is shown. Features made of silane molecules, with dimensions less than 10 nm are successfully patterned. In the frame of biodetection, this new nanopatterning technique is proposed as an alternative to dip-pen nanolithography in nanoarray manufacture. Moreover, the small dimensions of the obtained patterns pave the way for the achievement of single-molecule nanoarrays.
Books on the topic "Biomolecular Sensors"
NATO Advanced Study Institute on Molecular Electronics: Bio-sensor and Bio-computer (2002 Pisa, Italy). Molecular electronics: Bio-sensors and bio-computers. Dordrecht: Kluwer Academic Publishers, 2003.
Find full textEmil, Paleček, Scheller F, and Wang Joseph 1948-, eds. Electrochemistry of nucleic acids and proteins: Towards electrochemical sensors for genomics and proteomics. Amsterdam: Elsevier, 2005.
Find full textLowe, Christopher R., and Electra Gizeli. Biomolecular Sensors. Taylor & Francis Group, 2002.
Find full text(Editor), Electra Gizeli, and Christopher R. Lowe (Editor), eds. Biomolecular Sensors. CRC, 2002.
Find full textLowe, Christopher R., and Electra Gizeli. Biomolecular Sensors. Taylor & Francis Group, 2002.
Find full textLowe, Christopher R., and Electra Gizeli. Biomolecular Sensors. Taylor & Francis Group, 2002.
Find full textLowe, Christopher, and Electra Gizeli. Biomolecular Sensors. Taylor & Francis Group, 2002.
Find full textLowe, Christopher R., and Electra Gizeli. Biomolecular Sensors. Taylor & Francis Group, 2002.
Find full textLowe, Christopher R., and Electra Gizeli. Biomolecular Sensors. Taylor & Francis Group, 2002.
Find full textKatz, Evgeny. Biomolecular Information Processing: From Logic Systems to Smart Sensors and Actuators. Wiley-VCH Verlag GmbH, 2012.
Find full textBook chapters on the topic "Biomolecular Sensors"
Rickert, Jan, Thomas Wessa, and Wolfgang Göpel. "Sensors for biomolecular studies." In Microsystem Technology: A Powerful Tool for Biomolecular Studies, 279–310. Basel: Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8817-2_12.
Full textWu, Yuqiang, and Frank Vollmer. "Whispering Gallery Mode Biomolecular Sensors." In Springer Series in Optical Sciences, 323–49. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-40003-2_9.
Full textPark, Young June, Jinhong Ahn, Jaeheung Lim, and Seok Hyang Kim. "“C-chip” Platform for Electrical Biomolecular Sensors." In Smart Sensors and Systems, 3–23. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14711-6_1.
Full textStuart, Jeffrey A., Duane L. Marcy, Kevin J. Wise, and Robert R. Birge. "Biomolecular Electronic Device Applications of Bacteriorhodopsin." In Molecular Electronics: Bio-sensors and Bio-computers, 265–99. Dordrecht: Springer Netherlands, 2003. http://dx.doi.org/10.1007/978-94-010-0141-0_10.
Full textDiaconu, Gabriela, and Thomas Schäfer. "Sensing Techniques Involving Thin Films for Studying Biomolecular Interactions and Membrane Fouling Phenomena." In Smart Membranes and Sensors, 145–60. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9781119028642.ch5.
Full textNavratilova, Iva, and David G. Myszka. "Investigating Biomolecular Interactions and Binding Properties Using SPR Biosensors." In Springer Series on Chemical Sensors and Biosensors, 155–76. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/5346_018.
Full textBeratan, David N. "Molecular Control of Electron Transfer Events Within and Between Biomolecules." In Molecular Electronics: Bio-sensors and Bio-computers, 227–36. Dordrecht: Springer Netherlands, 2003. http://dx.doi.org/10.1007/978-94-010-0141-0_7.
Full textWells, Craig C., Dmitriy V. Melnikov, and Maria E. Gracheva. "Computational Modeling of Biomolecule Sensing with a Solid-State Membrane." In Springer Series on Chemical Sensors and Biosensors, 215–38. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/5346_2017_5.
Full textBaier, Claudia, Hadwig Sternschulte, Andrej Denisenko, Alice Schlichtiger, and Ulrich Stimming. "Electrochemical Response of Biomolecules on Carbon Substrates: Comparison between Oxidized HOPG and O-Terminated Boron-Doped CVD Diamond." In Nanotechnological Basis for Advanced Sensors, 471–82. Dordrecht: Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-0903-4_49.
Full textFacci, Paolo, Alberto Diaspro, and Claudio Nicolini. "A CIDS-Activated Cell Sensor for Monitoring DNA Superstructures." In From Neural Networks and Biomolecular Engineering to Bioelectronics, 223–26. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-1088-2_18.
Full textConference papers on the topic "Biomolecular Sensors"
Yue, Min, Jeanne C. Stachowiak, Henry Lin, Kenneth Castelino, Ram Datar, Karolyn Hansen, Thomas Thundat, Arup Chakraborty, Richard J. Cote, and Arun Majumdar. "Nanomechanical Sensor Array for Detection of Biomolecular Bindings: Toward a Label-Free Clinical Assay for Serum Tumor Markers." In ASME 2004 3rd Integrated Nanosystems Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/nano2004-46034.
Full textManalis, Scott. "Microdevices for biomolecular and single cell detection." In 2007 IEEE Sensors. IEEE, 2007. http://dx.doi.org/10.1109/icsens.2007.4388318.
Full textMisiakos, Konstantinos, Elisavet Mayrogiannopoulou, Panayiota Petrou, and Sotirios Kakabakos. "Monolithic silicon optical microdevices for biomolecular sensing." In 2009 IEEE Sensors. IEEE, 2009. http://dx.doi.org/10.1109/icsens.2009.5398131.
Full textLi, Xiang, Haocheng Yin, and Long Que. "A microfluidic nanostructured fluorescence sensor for biomolecular binding detection." In 2013 IEEE Sensors. IEEE, 2013. http://dx.doi.org/10.1109/icsens.2013.6688281.
Full textShen, Zuliang, Herman O. Sintim, and Steve Semancik. "Temperature-controlled electrochemical microwell platform for studying biomolecular interactions." In 2013 IEEE Sensors. IEEE, 2013. http://dx.doi.org/10.1109/icsens.2013.6688368.
Full textVaiano, P., G. Quero, S. Spaziani, A. Micco, M. Principe, M. Consales, and A. Cusano. "Optical fiber Meta-tips as valuable platforms for enhanced biological sensing." In Optical Fiber Sensors. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/ofs.2022.tu2.2.
Full textTemiz, Yuksel, Anna Ferretti, Enrico Accastelli, Yusuf Leblebici, and Carlotta Guiducci. "Robust microelectrodes developed for improved stability in electrochemical characterization of biomolecular layers." In 2010 Ninth IEEE Sensors Conference (SENSORS 2010). IEEE, 2010. http://dx.doi.org/10.1109/icsens.2010.5690737.
Full textZapata, A. M., E. T. Carlen, E. S. Kim, J. Hsiao, D. Traviglia, and M. S. Weinberg. "Biomolecular Sensing using Surface Micromachined Silicon Plates." In TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference. IEEE, 2007. http://dx.doi.org/10.1109/sensor.2007.4300259.
Full textLi, Yang-Guo, and Mohammad Rafiqul Haider. "A low-power neuromorphic CMOS sensor circuit for the implanted biomolecular detections." In 2013 IEEE Sensors. IEEE, 2013. http://dx.doi.org/10.1109/icsens.2013.6688234.
Full textPalla, Mirko, Shiv Kumar, Zengmin Li, Steffen Jockusch, James J. Russo, Jingyue Ju, Filippo G. Bosco, et al. "Click chemistry based biomolecular conjugation monitoring using surface-enhanced Raman spectroscopy mapping." In 2016 IEEE SENSORS. IEEE, 2016. http://dx.doi.org/10.1109/icsens.2016.7808595.
Full text