Relevant bibliographies by topics / Biomedical inhalation

Academic literature on the topic 'Biomedical inhalation'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Biomedical inhalation"

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Smutney, Chad C., Emil M. Friedman, John M. Polidoro, and Nikhil Amin. "Inspiratory Efforts Achieved in Use of the Technosphere® Insulin Inhalation System." Journal of Diabetes Science and Technology 3, no. 5 (September 2009): 1175–82. http://dx.doi.org/10.1177/193229680900300524.

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Objective: The Technosphere® Insulin (IT) inhalation system comprises TI powder premetered into unit dose cartridges and the patient-friendly, reusable, breath-powered MedTone® inhaler. This high-resistance system uses a patient's inspiratory effort to effect TI powder de-agglomeration and promote subsequent deep-lung delivery. This study reports on flow and pressure data achieved by patients with diabetes using the MedTone system. Method: MedTone inhalers containing empty cartridges were adapted with pneumotach measuring devices to capture inhalation profiles. The measuring apparatuses had negligible impact on the nominal MedTone system resistance level of 0.117 kPa0.5/liters/min. Each of 56 subjects inhaled twice to mimic TI clinical study dosing instructions. Achieved inhalation profiles were characterized by peak inspiratory flow (PIF), peak inspiratory pressure (PIP), and average pressure drop from the time of PIP to 4 s ( Pavg) Results: The achieved mean PIF (± standard deviation [SD]) in all subjects was 26.74 (±6.06) liters/min after the first inhalation and was similar to the mean PIF of 26.25 (±6.23) liters/min achieved after the second inhalation. Mean PIP (±SD) achieved by subjects was 8.49 (±2.86) and 8.1 (±2.99) kPa, and mean Pavg drop (±SD) in all subjects was 6.53 (±2.24) and 6.09 (±2.08) kPa after the respective inhalations. Conclusion: Patients with diabetes demonstrated consistent inhalation efforts over two inhalations using the MedTone system. The achieved PIFs and PIPs demonstrate the capacity of this population to obtain sufficient inspiratory effort necessary for delivery of TI using the MedTone inhaler. Adequate postpeak pressures were also revealed, further supporting reliable and sustained inhalation efforts.
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Pantusa, Victor P., Thomas H. Stock, Maria T. Morandi, Ronald B. Harrist, and Masoud Afshar. "Inhalation Exposures to Acrylamide in Biomedical Laboratories." AIHA Journal 63, no. 4 (July 2002): 468–73. http://dx.doi.org/10.1080/15428110208984735.

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Egbuna, Chukwuebuka, Vijaykumar K. Parmar, Jaison Jeevanandam, Shahira M. Ezzat, Kingsley C. Patrick-Iwuanyanwu, Charles Oluwaseun Adetunji, Johra Khan, et al. "Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology." Journal of Toxicology 2021 (July 30, 2021): 1–21. http://dx.doi.org/10.1155/2021/9954443.

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Nanoparticles are of great importance in development and research because of their application in industries and biomedicine. The development of nanoparticles requires proper knowledge of their fabrication, interaction, release, distribution, target, compatibility, and functions. This review presents a comprehensive update on nanoparticles’ toxic effects, the factors underlying their toxicity, and the mechanisms by which toxicity is induced. Recent studies have found that nanoparticles may cause serious health effects when exposed to the body through ingestion, inhalation, and skin contact without caution. The extent to which toxicity is induced depends on some properties, including the nature and size of the nanoparticle, the surface area, shape, aspect ratio, surface coating, crystallinity, dissolution, and agglomeration. In all, the general mechanisms by which it causes toxicity lie on its capability to initiate the formation of reactive species, cytotoxicity, genotoxicity, and neurotoxicity, among others.
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Roustan, Audrey, Jeanne Perrin, Anaïs Berthelot-Ricou, Erica Lopez, Alain Botta, and Blandine Courbiere. "Evaluating methods of mouse euthanasia on the oocyte quality: cervical dislocation versus isoflurane inhalation." Laboratory Animals 46, no. 2 (April 2012): 167–69. http://dx.doi.org/10.1258/la.2012.011115.

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Cervical dislocation is a commonly used method of mouse euthanasia. Euthanasia by isoflurane inhalation is an alternative method which allows the sacrifice of several mice at the same time with an anaesthesia, in the aim to decrease pain and animal distress. The objective of our study was to assess the impact of these two methods of euthanasia on the quality of mouse oocytes. By administering gonadotropins, we induced a superovulation in CD1 female mice. Mice were randomly assigned to euthanasia with cervical dislocation and isoflurane inhalation. Oviducts were collected and excised to retrieve metaphase II oocytes. After microscopic examination, oocytes were classified into three groups: intact, fragmented/cleaved and atretic. Intact metaphase II oocytes were employed for biomedical research. A total of 1442 oocytes in the cervical dislocation group were compared with 1230 oocytes in the isoflurane group. In the cervical dislocation group, 93.1% of the oocytes were intact, versus 65.8% in the isoflurane group ( P ≤ 0.001). In light of these results, we conclude that cervical dislocation is the best method of mouse euthanasia for obtaining intact oocytes for biomedical research.
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Sergeev, I. K., U. G. Sterlin, and V. V. Subbotin. "Multipurpose Device for Inhalation Anesthesia." Biomedical Engineering 47, no. 1 (May 2013): 26–31. http://dx.doi.org/10.1007/s10527-013-9327-8.

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Kim, Young Hun, Mi Seong Jo, Jin Kwon Kim, Jae Hoon Shin, Jin Ee Baek, Hye Seon Park, Hyo Jin An, et al. "Short-term inhalation study of graphene oxide nanoplates." Nanotoxicology 12, no. 3 (February 1, 2018): 224–38. http://dx.doi.org/10.1080/17435390.2018.1431318.

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Boldyrev, Artur, Marat Ziganshin, Alexander Osipov, Timur Mukhametzyanov, Nikolay Lyadov, Alexander Klimovitskii, and Alexander Gerasimov. "Lysozyme-Based Composite Drug Preparations for Inhalation Administration." BioNanoScience 9, no. 1 (November 20, 2018): 131–40. http://dx.doi.org/10.1007/s12668-018-0576-6.

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Shi, H., C. Kleinstreuer, and Z. Zhang. "Laminar Airflow and Nanoparticle or Vapor Deposition in a Human Nasal Cavity Model." Journal of Biomechanical Engineering 128, no. 5 (March 6, 2006): 697–706. http://dx.doi.org/10.1115/1.2244574.

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The transport and deposition of nanoparticles, i.e., dp=1–2nm, or equivalent vapors, in the human nasal cavities is of interest to engineers, scientists, air-pollution regulators, and healthcare officials alike. Tiny ultrafine particles, i.e., dp≤5nm, are of special interest because they are most rapidly absorbed and hence have an elevated toxic or therapeutic impact when compared to larger particles. Assuming transient laminar 3-D incompressible flow in a representative human nasal cavity, the cyclic airflow pattern as well as local and overall nanoparticle depositions were computationally simulated and analyzed. The focus was on transient effects during inhalation/exhalation as compared to the steady-state assumption typically invoked. Then, an equation for a matching steady-state inhalation flow rate was developed that generates the same deposition results as cyclic inhalation. Of special interest is the olfactory region where the narrow channel surfaces receive only about one-half of a percent of the inhaled nanoparticles because the airflow bypasses these recesses located in the superior-most portions in the geometrically complex nasal cavities.
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König, F., E. Ogris, and H. Aiginger. "STRAHLENBELASTUNG DURCH INHALATION VON JOD-131 AUF EINER NUKLEARMEDIZINISCHEN BETTENSTATION." Biomedizinische Technik/Biomedical Engineering 43, s2 (1998): 192–94. http://dx.doi.org/10.1515/bmte.1998.43.s2.192.

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LIN, SHYAN-LUNG, NAI-REN GUO, and TSUNG-CHI CHEN. "OPTIMAL RESPIRATORY CONTROL SIMULATION AND COMPARATIVE STUDY OF HYPERCAPNIC VENTILATORY RESPONSES TO EXTERNAL DEAD SPACE LOADING." Journal of Mechanics in Medicine and Biology 14, no. 02 (March 10, 2014): 1450014. http://dx.doi.org/10.1142/s0219519414500146.

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There has been considerable research effort regarding ventilatory responses to breathing with an imposed external dead space, and inhalation of fixed levels of CO 2 by human subjects. A human respiratory control model incorporating the optimality hypothesis can successfully demonstrate ventilatory responses to both chemical stimuli and muscular exercise. In this study, to verify the model behavior of the optimal chemical–mechanical respiratory control model, we simulated the ventilatory control under dead space loading and CO 2 inhalation. The simulation was provided by a LabVIEW® based human respiratory control simulator and signal monitoring system. The dead space measurement was described with two distinct models, derived from Gray and Coon, and predicted behaviors with corresponding ventilatory responses were investigated and compared with experimental findings. While both dead space models produced satisfactory predictions on simulated optimal [Formula: see text] versus Pa CO 2, [Formula: see text] versus Pa CO 2, F versus PI CO 2, VT versus PI CO 2, VD-total versus VT, VD- total /VT versus VT, [Formula: see text] versus VT and [Formula: see text] versus VT relationships, Gray's model provided better correlation and more consistent results throughout most of the ventilatory responses. The study of relative behavior of respiratory signals and comparative relationship of the ventilator responses between dead space loading during rest and CO 2 inhalation will certainly provide valuable understanding of increases in central respiratory motor command output of human respiratory control, which is also associated with Dyspnea on exertion, and give potential clinical perspective to realize the impaired ability to excrete CO 2 in patients diagnosed with acute respiratory distress syndrome.
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Dissertations / Theses on the topic "Biomedical inhalation"

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Kemlo, Grant. "An investigation into the effects of intermittent hypoxia on patients with essential hypertension." Thesis, 2005. https://vuir.vu.edu.au/843/.

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While physiological effects of chronic inhalation of hypoxic air may be detrimental. studies have shown that intermittently breathing hypoxic air can be beneficial. Some of these benefits include increased red blood cell count, haemoglobin concentration, tissue capillarisation, and decreased heart rate. An interesting effect observed following intermittent exposure to hypoxia is a noticeable decrease in blood pressure (BP) in people with essential hypertension. This study aimed to repeat these results using a small, inexpensive, esy-to-use, portable Hypoxicator rather then the bulky, expensive, fixed Hypoxicators used in past studies. At this stage, the researchers do not have sufficient data to gain statistically significant results nor see any trends, as IH (intermittent Hypoxia) has shown to have no significant impact until at least two weeks of intervention. Further analyses will be undertaken at the completion of the data collection. This minor thesis was written by a post-graduate student as part of the requirements of the Master of Health Science (Osteopathy) program.
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Book chapters on the topic "Biomedical inhalation"

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Gaté, Laurent, Frédéric Cosnier, and Flemming R. Cassee. "Rodent Inhalation Studies in Nanomaterial Risk Assessment." In Biomedical Application of Nanoparticles, 163–88. Boca Raton : Taylor & Francis, 2017.: CRC Press, 2017. http://dx.doi.org/10.1201/9781315152363-7.

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Müller, Loretta, Andrea D. Lehmann, Blair D. Johnston, Fabian Blank, Peter Wick, Alke Fink, and Barbara Rothen-Rutishauser. "Inhalation Pathway as a Promising Portal of Entry: What Has to Be Considered in Designing New Nanomaterials for Biomedical Application?" In Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology, 205–22. Chichester, UK: John Wiley & Sons, Ltd, 2014. http://dx.doi.org/10.1002/9781118856017.ch12.

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"Particle Engineering for Inhalational Drug Delivery." In Biomedical Nanosensors, 255–86. Jenny Stanford Publishing, 2012. http://dx.doi.org/10.1201/b13721-10.

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Ichimura, Yasunori, and David Baker. "Acute Inhalational Injury." In Reference Module in Biomedical Sciences. Elsevier, 2019. http://dx.doi.org/10.1016/b978-0-12-801238-3.11495-3.

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Conference papers on the topic "Biomedical inhalation"

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Kotz, K. T., K. Amin, J. M. Orduna, W. A. Boenig, and G. W. Faris. "Image contrast enhancement following carbogen inhalation." In Biomedical Topical Meeting. Washington, D.C.: OSA, 2004. http://dx.doi.org/10.1364/bio.2004.thf36.

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Pantusa, V. P., T. H. Stock, M. T. Morandi, and M. Afshar. "373. Inhalation Exposures to Acrylamide in Biomedical Laboratories." In AIHce 1998. AIHA, 1999. http://dx.doi.org/10.3320/1.2762777.

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Yi, Cao, Ke Ke, Lou Xiaohua, and Yang Xu. "Up-Regulation of GSNO Reductase in Mice Lungs by Formaldehyde Inhalation." In 2007 1st International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2007. http://dx.doi.org/10.1109/icbbe.2007.79.

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Inthavong, K., J. Wen, and J. Y. Tu. "Inhalation of Toxic and Therapeutic Particles in a Human Nasal Cavity." In 2008 2nd International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2008. http://dx.doi.org/10.1109/icbbe.2008.755.

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Dixit, Sanhita S., Hanyoup Kim, Brendan Visser, Christopher Comstock, and Gregory W. Faris. "Hyperoxic/Hypercapnic Gas Inhalation as a Route to Increase Contrast from Tumor Tissue in Near-Infrared Imaging of Breast Tissue." In Biomedical Optics. Washington, D.C.: OSA, 2008. http://dx.doi.org/10.1364/biomed.2008.btud4.

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Sanpanich, A., W. Sroykham, C. Phairoh, W. Angkhananuwat, K. Petsarb, and Y. Kajornpredanon. "An inhalation air flow pattern in human respiratory tract: Partial secretion block case." In 2016 9th Biomedical Engineering International Conference (BMEiCON). IEEE, 2016. http://dx.doi.org/10.1109/bmeicon.2016.7859585.

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Mendes, Pedro J., Joa˜o M. M. Sousa, and Joa˜o F. Pinto. "A Virtual Apparatus for Design and Testing of New Drug Formulations and Devices for Inhalation Therapy." In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38027.

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Delivery of drugs to the lungs as aerosols is regarded as an excellent route for local or systemic administration of drugs. Aerosols have been used traditionally for treating illnesses of the respiratory tract (e.g. asthma), but new perspectives and needs on inhalation therapy have recently emerged (e.g. insulin). The percentage of drug that reaches the targeted region, the so-called respirable fraction (RF), is in average only 30% of the dose provided to the patient. Thus, the development of more efficient formulations and devices remains an important issue.
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Liu, Xiao-li, Yan-ru Hu, Jing Qiao, and Hong-lei Li. "Notice of Retraction: Effects of Sulfur Dioxide Inhalation on Myocardial Function in Exercise Rat." In 2011 5th International Conference on Bioinformatics and Biomedical Engineering. IEEE, 2011. http://dx.doi.org/10.1109/icbbe.2011.5781247.

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Siegrist, Jonathan, Mary Amasia, Horacio Kido, Jim Zoval, and Marc Madou. "Microfluidic CD-Based Systems Toward Rapid Anthrax Detection in Whole Blood." In ASME 2008 3rd Frontiers in Biomedical Devices Conference. ASMEDC, 2008. http://dx.doi.org/10.1115/biomed2008-38094.

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Anthrax is an acute and deadly disease caused by the bacterium Bacillus anthracis. Upon exposure, usually through inhalation, ingestion, or cutaneous contact, B. anthracis spores begin multiplying, creating a life-threatening situation. If not quickly detected and treated, humans can die within several days. With renewed bio-terrorism concerns, there is a need for a rapid and automated system capable of sample (respiratory or blood) to answer (positive infection) so that quarantine procedures and treatment can be administered immediately. Microfluidic platforms hold great promise of fulfilling these requirements.
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Zhang, Juan, Ge Yu Liang, Kai Hong Fan, Li Hong Yin, and Yue Pu Pu. "Chronic Hematologic Toxicity with Inhalation Exposure to Low Concentration of Benzene in BALB/C Mice." In 2010 4th International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2010. http://dx.doi.org/10.1109/icbbe.2010.5515446.

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