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Journal articles on the topic 'Biomedical and chemical applications'

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Author: Grafiati

Published: 6 September 2023

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1

Gibas, Iwona, and Helena Janik. "Review: Synthetic Polymer Hydrogels for Biomedical Applications." Chemistry & Chemical Technology 4, no. 4 (December 15, 2010): 297–304. http://dx.doi.org/10.23939/chcht04.04.297.

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Synthetic polymer hydrogels constitute a group of biomaterials, used in numerous biomedical disciplines, and are still developing for new promising applications. The aim of this study is to review information about well known and the newest hydrogels, show the importance of water uptake and cross-linking type and classify them in accordance with their chemical structure.

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2

Kai, Dan, and Xian Jun Loh. "Polyhydroxyalkanoates: Chemical Modifications Toward Biomedical Applications." ACS Sustainable Chemistry & Engineering 2, no. 2 (October 30, 2013): 106–19. http://dx.doi.org/10.1021/sc400340p.

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3

Wei, Min, Jiyoung Lee, Fan Xia, Peihua Lin, Xi Hu, Fangyuan Li, and Daishun Ling. "Chemical design of nanozymes for biomedical applications." Acta Biomaterialia 126 (May 2021): 15–30. http://dx.doi.org/10.1016/j.actbio.2021.02.036.

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4

Zhou, Hua, Jingyun Tan, and Xuanjun Zhang. "Nanoreactors for Chemical Synthesis and Biomedical Applications." Chemistry – An Asian Journal 14, no. 19 (September 17, 2019): 3240–50. http://dx.doi.org/10.1002/asia.201900967.

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5

Zhao, Hanjun. "Black Phosphorus Nanosheets: Synthesis and Biomedical Applications." Journal of Physics: Conference Series 2566, no. 1 (August 1, 2023): 012015. http://dx.doi.org/10.1088/1742-6596/2566/1/012015.

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Abstract Since 2014, black phosphorus (BP) has gained more and more attention because of its unique physicochemical properties. In particular, with unique electrical, optical, and biodegradable performances, BP may serve as an alternative for other two-dimensional nanomaterials (2DNMs) in biomedical applications. However, the practical application of BP in the biomedical field still faces great challenges. In this article, we focus on the various synthesis methods of BP, including the exfoliation method, chemical vapor deposition (CVD) method, and wet-chemical self-assembly method, and recent advances of BP in biomedical fields, such as biosensing, imaging, drug delivery, phototherapy, and bioactive phospho-therapy are highlighted. Finally, the current challenges of BP in biomedical applications are briefly discussed. It is believed that this article will provide effective scientific support for the development and application of BP.

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6

Ghajarieh, A., S. Habibi, and A. Talebian. "Biomedical Applications of Nanofibers." Russian Journal of Applied Chemistry 94, no. 7 (July 2021): 847–72. http://dx.doi.org/10.1134/s1070427221070016.

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Ghajarieh, A., S. Habibi, and A. Talebian. "Biomedical Applications of Nanofibers." Russian Journal of Applied Chemistry 94, no. 7 (July 2021): 847–72. http://dx.doi.org/10.1134/s1070427221070016.

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8

Marzo, Jose Luis, Josep Miquel Jornet, and Massimiliano Pierobon. "Nanonetworks in Biomedical Applications." Current Drug Targets 20, no. 8 (May 10, 2019): 800–807. http://dx.doi.org/10.2174/1389450120666190115152613.

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By interconnecting nanomachines and forming nanonetworks, the capacities of single nanomachines are expected to be enhanced, as the ensuing information exchange will allow them to cooperate towards a common goal. Nowadays, systems normally use electromagnetic signals to encode, send and receive information, however, in a novel communication paradigm, molecular transceivers, channel models or protocols use molecules. This article presents the current developments in nanomachines along with their future architecture to better understand nanonetwork scenarios in biomedical applications. Furthermore, to highlight the communication needs between nanomachines, two applications for nanonetworks are also presented: i) a new networking paradigm, called the Internet of NanoThings, that allows nanoscale devices to interconnect with existing communication networks, and ii) Molecular Communication, where the propagation of chemical compounds like drug particles, carry out the information exchange.

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De Sanctis, A., S. Russo, M. F. Craciun, A. Alexeev, M. D. Barnes, V. K. Nagareddy, and C. D. Wright. "New routes to the functionalization patterning and manufacture of graphene-based materials for biomedical applications." Interface Focus 8, no. 3 (April 20, 2018): 20170057. http://dx.doi.org/10.1098/rsfs.2017.0057.

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Graphene-based materials are being widely explored for a range of biomedical applications, from targeted drug delivery to biosensing, bioimaging and use for antibacterial treatments, to name but a few. In many such applications, it is not graphene itself that is used as the active agent, but one of its chemically functionalized forms. The type of chemical species used for functionalization will play a key role in determining the utility of any graphene-based device in any particular biomedical application, because this determines to a large part its physical, chemical, electrical and optical interactions. However, other factors will also be important in determining the eventual uptake of graphene-based biomedical technologies, in particular the ease and cost of manufacture of proposed device and system designs. In this work, we describe three novel routes for the chemical functionalization of graphene using oxygen, iron chloride and fluorine. We also introduce novel in situ methods for controlling and patterning such functionalization on the micro- and nanoscales. Our approaches are readily transferable to large-scale manufacturing, potentially paving the way for the eventual cost-effective production of functionalized graphene-based materials, devices and systems for a range of important biomedical applications.

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YU, Jing, Fei LIU, Zubair Yousaf Muhammad, and Yang-Long HOU. "Magnetic Nanoparticles: Chemical Synthesis, Functionalization and Biomedical Applications." Acta Agronomica Sinica 40, no. 10 (2013): 903. http://dx.doi.org/10.3724/sp.j.1206.2013.00276.

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Ratnatilaka Na Bhuket, Pahweenvaj, Jittima Amie Luckanagul, Pornchai Rojsitthisak, and Qian Wang. "Chemical modification of enveloped viruses for biomedical applications." Integrative Biology 10, no. 11 (2018): 666–79. http://dx.doi.org/10.1039/c8ib00118a.

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12

Di Paola, Luisa, Vincenzo Piemonte, and Angelo Basile. "Biomedical and biotechnological applications of chemical engineering methodologies." Asia-Pacific Journal of Chemical Engineering 9, no. 3 (April 22, 2014): 317. http://dx.doi.org/10.1002/apj.1816.

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13

Noriega-Luna, B., Luis A. Godínez, Francisco J. Rodríguez, A. Rodríguez, G. Zaldívar-Lelo de Larrea, C. F. Sosa-Ferreyra, R. F. Mercado-Curiel, J. Manríquez, and E. Bustos. "Applications of Dendrimers in Drug Delivery Agents, Diagnosis, Therapy, and Detection." Journal of Nanomaterials 2014 (April 15, 2014): 1–19. http://dx.doi.org/10.1155/2014/507273.

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In recent years, the application of dendrimers in biomedicine attracted much attention from scientists. Dendrimers are interesting for biomedical applications because of their characteristics, including: a hyperbranching, well-defined globular structures, excellent structural uniformity, multivalency, variable chemical composition, and high biological compatibility. In particular, the three-dimensional architecture of dendrimers can incorporate a variety of biologically active agents to form biologically active conjugates. This review of dendrimers focuses on their use as protein mimics, drug delivery agents, anticancer and antiviral therapeutics, and in biomedical diagnostic applications such as chemically modified electrodes.

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Petrov, Kirill D., and Alexey S. Chubarov. "Magnetite Nanoparticles for Biomedical Applications." Encyclopedia 2, no. 4 (November 14, 2022): 1811–28. http://dx.doi.org/10.3390/encyclopedia2040125.

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Magnetic nanoparticles (MNPs) have great potential in various areas such as medicine, cancer therapy and diagnostics, biosensing, and material science. In particular, magnetite (Fe3O4) nanoparticles are extensively used for numerous bioapplications due to their biocompatibility, high saturation magnetization, chemical stability, large surface area, and easy functionalization. This paper describes magnetic nanoparticle physical and biological properties, emphasizing synthesis approaches, toxicity, and various biomedical applications, focusing on the most recent advancements in the areas of therapy, diagnostics, theranostics, magnetic separation, and biosensing.

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Abu Owida, Hamza, Nidal M. Turab, and Jamal Al-Nabulsi. "Carbon nanomaterials advancements for biomedical applications." Bulletin of Electrical Engineering and Informatics 12, no. 2 (April 1, 2023): 891–901. http://dx.doi.org/10.11591/eei.v12i2.4310.

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The development of new technologies has helped tremendously in delivering timely, appropriate, acceptable, and reasonably priced medical treatment. Because of developments in nanoscience, a new class of nanostructures has emerged. Nanomaterials, because of their small size, display exceptional physio-chemical capabilities such as enhanced absorption and reactivity, increased surface area, molar extinction coefficients, tunable characteristics, quantum effects, and magnetic and optical properties. Researchers are interested in carbon-based nanomaterials due to their unique chemical and physical properties, which vary in thermodynamic, biomechanical, electrical, optical, and structural aspects. Due to their inherent properties, carbon nanomaterials, including fullerenes, graphene, carbon nanotubes (CNTs), and carbon nanofibers (CNFs), have been intensively studied for biomedical applications. This article is a review of the most recent findings about the development of carbon-based nanomaterials for use in biosensing, drug delivery, and cancer therapy, among other things.

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Chauhan, Divya, Mohammad Ashfaq, Neetu Talreja, and Ramalinga Viswanathan Managalraja. "2D Materials for Environment, Energy, and Biomedical Applications." Journal of Biomedical Research & Environmental Sciences 2, no. 10 (October 2021): 977–84. http://dx.doi.org/10.37871/jbres1340.

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Recently 2D materials are booming in the field of energy, environment, and biomedical application. Incorporation of metal/non-metal within 2D materials significantly influences the physical and chemical properties, making them intriguing materials for various applications. The advancement of 2D material requires strategic modification by manipulating the electronic structure, which remains a challenge. Herein, we describe 2D materials for the environment, energy, and biomedical application. A predominant aim of this short communication is to summarize the literature on the advanced environment, energy, and biomedical application (especially COVID-19).

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Xu, Jian-Lin, Zhi-Feng Liu, Xiao-Wei Zhang, Hai-Li Liu, and Yong Wang. "Microbial Oligosaccharides with Biomedical Applications." Marine Drugs 19, no. 6 (June 21, 2021): 350. http://dx.doi.org/10.3390/md19060350.

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Microbial oligosaccharides have been regarded as one of the most appealing natural products attributable to their potent and selective bioactivities, such as antimicrobial activity, inhibition of α-glucosidases and lipase, interference of cellular recognition and signal transduction, and disruption of cell wall biosynthesis. Accordingly, a handful of bioactive oligosaccharides have been developed for the treatment of bacterial infections and type II diabetes mellitus. Given that naturally occurring oligosaccharides have increasingly gained recognition in recent years, a comprehensive review is needed. The current review highlights the chemical structures, biological activities and divergent biosynthetic origins of three subgroups of oligomers including the acarviosine-containing oligosaccharides, saccharomicins, and orthosomycins.

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Bakhshpour, Monireh, Neslihan Idil, Işık Perçin, and Adil Denizli. "Biomedical Applications of Polymeric Cryogels." Applied Sciences 9, no. 3 (February 7, 2019): 553. http://dx.doi.org/10.3390/app9030553.

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The application of interconnected supermacroporous cryogels as support matrices for the purification, separation and immobilization of whole cells and different biological macromolecules has been well reported in literature. Cryogels have advantages over traditional gel carriers in the field of biochromatography and related biomedical applications. These matrices nearly mimic the three-dimensional structure of native tissue extracellular matrix. In addition, mechanical, osmotic and chemical stability of cryogels make them attractive polymeric materials for the construction of scaffolds in tissue engineering applications and in vitro cell culture, separation materials for many different processes such as immobilization of biomolecules, capturing of target molecules, and controlled drug delivery. The low mass transfer resistance of cryogel matrices makes them useful in chromatographic applications with the immobilization of different affinity ligands to these materials. Cryogels have been introduced as gel matrices prepared using partially frozen monomer or polymer solutions at temperature below zero. These materials can be produced with different shapes and are of interest in the therapeutic area. This review highlights the recent advances in cryogelation technologies by emphasizing their biomedical applications to supply an overview of their rising stars day to day.

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19

YANCONG, ZHANG, DOU LINBO, MA NING, WU FUHUA, and NIU JINCHENG. "BIOMEDICAL APPLICATIONS OF ELECTROSPUN NANOFIBERS." Surface Review and Letters 27, no. 11 (July 27, 2020): 2030001. http://dx.doi.org/10.1142/s0218625x20300014.

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Electrospun technology is a simple and flexible method for preparation of nanofiber materials with unique physical and chemical properties. The nanofiber diameter is adjustable from several nanometers to few microns during the preparation. Electrospun nanofiber materials are easy to be assembled into different shapes of three-dimensional structures. These materials exhibit high porosity and surface area and can simulate the network structures of collagen fibers in a natural extracellular matrix, thereby providing a growth microenvironment for tissue cells. Electrospun nanofibers therefore have extensive application prospects in the biomedicine field, including in aerospace, filtration, biomedical applications, and biotechnology. Nanotechnology has the potential to revolutionize many fields, such as surface microscopy, silicon fabrication, biochemistry, molecular biology, physical chemistry, and computational engineering, while the advent of nanofibers has increased the understanding of nanotechnology among academia, industry, and the general public. This paper mainly introduces the application of nanofiber materials in tissue engineering, drug release, wound dressing, and other biomedicine fields.

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20

Wang, Zhantong, Haiyan Gao, Yang Zhang, Gang Liu, Gang Niu, and Xiaoyuan Chen. "Functional ferritin nanoparticles for biomedical applications." Frontiers of Chemical Science and Engineering 11, no. 4 (February 15, 2017): 633–46. http://dx.doi.org/10.1007/s11705-017-1620-8.

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21

D’Ayala, Giovanna, Mario Malinconico, and Paola Laurienzo. "Marine Derived Polysaccharides for Biomedical Applications: Chemical Modification Approaches." Molecules 13, no. 9 (September 3, 2008): 2069–106. http://dx.doi.org/10.3390/molecules13092069.

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22

Yuan, Qing, Yaling Wang, Lina Zhao, Ru Liu, Fuping Gao, Liang Gao, and Xueyun Gao. "Peptide protected gold clusters: chemical synthesis and biomedical applications." Nanoscale 8, no. 24 (2016): 12095–104. http://dx.doi.org/10.1039/c6nr02750d.

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23

Kelgenbaeva, Zhazgul, Bektemir Murzubraimov, Artem Kozlovsky, Ruslan Adil Akai Tegin, Ainur Turdubai kyzy, Elmira Murzabekova, Janbolot Aidaraliev, and Begimzhan Dyusheeva. "Magnetic nanoparticles preparation by chemical reduction for biomedical applications." EPJ Web of Conferences 201 (2019): 01002. http://dx.doi.org/10.1051/epjconf/201920101002.

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This work presents Fe3O4 and AgFe nanoparticles with an average diameter of 25 and 15 nm synthesized by chemical reduction of corresponding salts under a mild condition. Cubic crystal structure and spherical shape of the nanoparticles were studied by X-ray diffraction, Field emission SEM and energy-dispersive spectroscopy analysis. For biomedical applications, the nanoparticles were tested against bacteria E.coli and results revealed AgFe nanoparticles’ antibacterial activity by forming lysis zone in scale of 0.5 mm.

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24

Leiner, Marc J. P. "Luminescence chemical sensors for biomedical applications: scope and limitations." Analytica Chimica Acta 255, no. 2 (December 1991): 209–22. http://dx.doi.org/10.1016/0003-2670(91)80049-y.

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25

Sun, Wei, Wenying Liu, Zhaoqiang Wu, and Hong Chen. "Chemical Surface Modification of Polymeric Biomaterials for Biomedical Applications." Macromolecular Rapid Communications 41, no. 8 (March 5, 2020): 1900430. http://dx.doi.org/10.1002/marc.201900430.

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26

Gharib, Ghazaleh, İsmail Bütün, Zülâl Muganlı, Gül Kozalak, İlayda Namlı, Seyedali Seyedmirzaei Sarraf, Vahid Ebrahimpour Ahmadi, Erçil Toyran, Andre J. van Wijnen, and Ali Koşar. "Biomedical Applications of Microfluidic Devices: A Review." Biosensors 12, no. 11 (November 16, 2022): 1023. http://dx.doi.org/10.3390/bios12111023.

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Both passive and active microfluidic chips are used in many biomedical and chemical applications to support fluid mixing, particle manipulations, and signal detection. Passive microfluidic devices are geometry-dependent, and their uses are rather limited. Active microfluidic devices include sensors or detectors that transduce chemical, biological, and physical changes into electrical or optical signals. Also, they are transduction devices that detect biological and chemical changes in biomedical applications, and they are highly versatile microfluidic tools for disease diagnosis and organ modeling. This review provides a comprehensive overview of the significant advances that have been made in the development of microfluidics devices. We will discuss the function of microfluidic devices as micromixers or as sorters of cells and substances (e.g., microfiltration, flow or displacement, and trapping). Microfluidic devices are fabricated using a range of techniques, including molding, etching, three-dimensional printing, and nanofabrication. Their broad utility lies in the detection of diagnostic biomarkers and organ-on-chip approaches that permit disease modeling in cancer, as well as uses in neurological, cardiovascular, hepatic, and pulmonary diseases. Biosensor applications allow for point-of-care testing, using assays based on enzymes, nanozymes, antibodies, or nucleic acids (DNA or RNA). An anticipated development in the field includes the optimization of techniques for the fabrication of microfluidic devices using biocompatible materials. These developments will increase biomedical versatility, reduce diagnostic costs, and accelerate diagnosis time of microfluidics technology.

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Hong, Heesun, Ok Joo Lee, Young Jin Lee, Ji Seung Lee, Olatunji Ajiteru, Hanna Lee, Ye Ji Suh, Md Tipu Sultan, Soon Hee Kim, and Chan Hum Park. "Cytocompatibility of Modified Silk Fibroin with Glycidyl Methacrylate for Tissue Engineering and Biomedical Applications." Biomolecules 11, no. 1 (December 29, 2020): 35. http://dx.doi.org/10.3390/biom11010035.

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Hydrogel with chemical modification has been used for 3D printing in the biomedical field of cell and tissue-based regeneration because it provides a good cellular microenvironment and mechanical supportive ability. As a scaffold and a matrix, hydrogel itself has to be modified chemically and physically to form a β-sheet crosslinking structure for the strength of the biomaterials. These chemical modifications could affect the biological damage done to encapsulated cells or surrounding tissues due to unreacted chemical residues. Biological assessment, including assessment of the cytocompatibility of hydrogel in clinical trials, must involve testing with cytotoxicity, irritation, and sensitization. Here, we modified silk fibroin and glycidyl methacrylate (Silk-GMA) and evaluated the physical characterizations, residual chemical detection, and the biological effect of residual GMA depending on dialysis periods. Silk-GMA depending on each dialysis period had a typical β-sheet structure in the characterization analysis and residual GMA decreased from dialysis day 1. Moreover, cell proliferation and viability rate gradually increased; additionally, necrotic and apoptotic cells decreased from dialysis day 2. These results indicate that the dialysis periods during chemical modification of natural polymer are important for removing unreacted chemical residues and for the potential application of the manufacturing standardization for chemically modified hydrogel for the clinical transplantation for tissue engineering and biomedical applications.

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Bianchi, Michele, and Gianluca Carnevale. "Innovative Nanomaterials for Biomedical Applications." Nanomaterials 12, no. 9 (May 5, 2022): 1561. http://dx.doi.org/10.3390/nano12091561.

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Parveen, Israt, Md Iqbal Mahmud, and Ruhul A. Khan. "Biodegradable Natural Polymers for Biomedical Applications." Scientific Review, no. 53 (April 4, 2019): 67–80. http://dx.doi.org/10.32861/sr.53.67.80.

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Biodegradable polymers as biomaterial are hotcake nowadays especially in medical and pharmaceutical applications. The present contribution comprises an overview of the biodegradable polymers for various biomedical applications. To meet the need of modern medicine, their physical, chemical, functional, biomechanical are highlighted as well as biodegradation properties like non-toxicity, low antigenicity, high bio-activity etc. This review summarizes the emerging and innovative field of biopolymer with the focus on tissue engineering, temporary implants, wound healing, and drug delivery applications etc.

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Lee, DaeYong, N. Rejinold, Seong Jeong, and Yeu-Chun Kim. "Stimuli-Responsive Polypeptides for Biomedical Applications." Polymers 10, no. 8 (July 27, 2018): 830. http://dx.doi.org/10.3390/polym10080830.

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Stimuli-responsive polypeptides have gained attention because desirable bioactive properties can be easily imparted to them while keeping their biocompatibility and biodegradability intact. In this review, we summarize the most recent advances in various stimuli-responsive polypeptides (pH, reduction, oxidation, glucose, adenosine triphosphate (ATP), and enzyme) over the past five years. Various synthetic strategies exploited for advanced polypeptide-based materials are introduced, and their applicability in biomedical fields is discussed. The recent polypeptides imparted with new stimuli-responsiveness and their novel chemical and physical properties are explained in this review.

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Das, Surojeet, Vivek Kumar, Rini Tiwari, Leena Singh, and Sachidanand Singh. "RECENT ADVANCES IN HYDROGELS FOR BIOMEDICAL APPLICATIONS." Asian Journal of Pharmaceutical and Clinical Research 11, no. 11 (November 7, 2018): 62. http://dx.doi.org/10.22159/ajpcr.2018.v11i11.27921.

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Hydrogels are three-dimensional polymeric network, capable of entrapping substantial amounts of fluids. Hydrogels are formed due to physical or chemical cross-linking in different synthetic and natural polymers. Recently, hydrogels have been receiving much attention for biomedical applications due to their innate structure and compositional similarities to the extracellular matrix. Hydrogels fabricated from naturally derived materials provide an advantage for biomedical applications due to their innate cellular interactions and cellular-mediated biodegradation. Synthetic materials have the advantage of greater tunability when it comes to the properties of hydrogels. There has been considerable progress in recent years in addressing the clinical and pharmacological limitations of hydrogels for biomedical applications. The primary objective of this article is to review the classification of hydrogels based on their physical and chemical characteristics. It also reviews the technologies adopted for hydrogel fabrication and the different applications of hydrogels in the modern era.

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Turhan, Emine Ayşe, Ahmet Engin Pazarçeviren, Zafer Evis, and Ayşen Tezcaner. "Properties and applications of boron nitride nanotubes." Nanotechnology 33, no. 24 (March 30, 2022): 242001. http://dx.doi.org/10.1088/1361-6528/ac5839.

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Abstract Nanomaterials have received increasing attention due to their controllable physical and chemical properties and their improved performance over their bulk structures during the last years. Carbon nanostructures are one of the most widely searched materials for use in different applications ranging from electronic to biomedical because of their exceptional physical and chemical properties. However, BN nanostructures surpassed the attention of the carbon-based nanostructure because of their enhanced thermal and chemical stabilities in addition to structural similarity with the carbon nanomaterials. Among these nanostructures, one dimensional-BN nanostructures are on the verge of development as new materials to fulfill some necessities for different application areas based on their excellent and unique properties including their tunable surface and bandgap, electronic, optical, mechanical, thermal, and chemical stability. Synthesis of high-quality boron nitride nanotubes (BNNTs) in large quantities with novel techniques provided greater access, and increased their potential use in nanocomposites, biomedical fields, and nanodevices as well as hydrogen uptake applications. In this review, properties and applications of one-dimensional BN (1D) nanotubes, nanofibers, and nanorods in hydrogen uptake, biomedical field, and nanodevices are discussed in depth. Additionally, research on native and modified forms of BNNTs and also their composites with different materials to further improve electronic, optical, structural, mechanical, chemical, and biological properties are also reviewed. BNNTs find many applications in different areas, however, they still need to be further studied for improving the synthesis methods and finding new possible future applications.

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Zheng, Chuan Lin, Rong Qi, and Wu Bao Yang. "MPACVD Nanocrystalline Diamond for Biomedical Applications." Key Engineering Materials 280-283 (February 2007): 1595–98. http://dx.doi.org/10.4028/www.scientific.net/kem.280-283.1595.

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In the present paper, nanocrystalline diamond films (NDFs) were fabricated on optical glass using microwave plasma assisted chemical vapor deposition (MPACVD). The suitable processing parameters are as followings: methane concentration 3% in argon, total deposition pressure 13.3 kPa, substrate temperature 500 °C. The diamond films were characterized by means of scanning electron microscopy (SEM), X-ray diffraction (XRD) and Raman spectroscopy. In vitro osteoblast cell cultures and platelet adhesion tests were applied to evaluate the biocompatibility of the nanocrystalline diamond films (NDFs). All results indicate that the diamond films exhibit better tissue compatibility and hemocompatibility which are very suitable for biomedical applications.

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Vecbiskena, Linda, Luigi de Nardo, and Roberto Chiesa. "Nanostructured Calcium Phosphates for Biomedical Applications." Key Engineering Materials 604 (March 2014): 212–15. http://dx.doi.org/10.4028/www.scientific.net/kem.604.212.

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This work is focused on the phase transformation from amorphous calcium phosphate (ACP) to nanostructured hydroxyapatite (HA) or tricalcium phosphate (TCP). Amorphous calcium phosphates with Ca/P molar ratio near 1.67 and 1.5 were synthesized by wet-chemical precipitation method and treated with ethanol. Upon thermal treatment, ACP clusters about 50 nm create a nanostructured HA or TCP. The highlights of this research: The precipitate treatment with ethanol provided a pure α-TCP that was found to be stable up to 1000 °C. HA is obtained from the ACP precursor synthesized using also ammonium dihydrogen phosphate.

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35

Song, Xiao-Rong, Nirmal Goswami, Huang-Hao Yang, and Jianping Xie. "Functionalization of metal nanoclusters for biomedical applications." Analyst 141, no. 11 (2016): 3126–40. http://dx.doi.org/10.1039/c6an00773b.

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Metal nanoclusters (NCs) are emerging as a new class of functional nanomaterials in the area of biological sensing, labelling, imaging and therapy due to their unique physical and chemical properties, such as ultrasmall size, HOMO–LUMO transition, strong luminescence together with good photostability and biocompatibility.

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Aflori, Magdalena. "Smart Nanomaterials for Biomedical Applications—A Review." Nanomaterials 11, no. 2 (February 4, 2021): 396. http://dx.doi.org/10.3390/nano11020396.

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Recent advances in nanotechnology have forced the obtaining of new materials with multiple functionalities. Due to their reduced dimensions, nanomaterials exhibit outstanding physio-chemical functionalities: increased absorption and reactivity, higher surface area, molar extinction coefficients, tunable plasmonic properties, quantum effects, and magnetic and photo properties. However, in the biomedical field, it is still difficult to use tools made of nanomaterials for better therapeutics due to their limitations (including non-biocompatible, poor photostabilities, low targeting capacity, rapid renal clearance, side effects on other organs, insufficient cellular uptake, and small blood retention), so other types with controlled abilities must be developed, called “smart” nanomaterials. In this context, the modern scientific community developed a kind of nanomaterial which undergoes large reversible changes in its physical, chemical, or biological properties as a consequence of small environmental variations. This systematic mini-review is intended to provide an overview of the newest research on nanosized materials responding to various stimuli, including their up-to-date application in the biomedical field.

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Roriz, Paulo, Susana Silva, Orlando Frazão, and Susana Novais. "Optical Fiber Temperature Sensors and Their Biomedical Applications." Sensors 20, no. 7 (April 9, 2020): 2113. http://dx.doi.org/10.3390/s20072113.

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The use of sensors in the real world is on the rise, providing information on medical diagnostics for healthcare and improving quality of life. Optical fiber sensors, as a result of their unique properties (small dimensions, capability of multiplexing, chemical inertness, and immunity to electromagnetic fields) have found wide applications, ranging from structural health monitoring to biomedical and point-of-care instrumentation. Furthermore, these sensors usually have good linearity, rapid response for real-time monitoring, and high sensitivity to external perturbations. Optical fiber sensors, thus, present several features that make them extremely attractive for a wide variety of applications, especially biomedical applications. This paper reviews achievements in the area of temperature optical fiber sensors, different configurations of the sensors reported over the last five years, and application of this technology in biomedical applications.

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Dang Dinh Khoi. "Graphitic carbon nitride quantum dots: Synthesis and applications." Journal of Technical Education Science, no. 67 (December 17, 2021): 58–73. http://dx.doi.org/10.54644/jte.67.2021.1090.

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Graphitic-carbon nitride quantum dots (g-CNQDs), a rising star in the carbon nitride family, has shown great potential in many fields including chemical and biomedical applications due to their good biocompatibility, stable fluorescence, high quantum yield, and nontoxicity. For this reason, enormous efforts have been devoted to optimizing synthetic methods and structures of g-CNQDs to discover the inner properties and structural features in the intriguing system. Also, a vast number of studies have been pursued to discuss the potential applications of g-CNQDs in chemical and biomedical areas. In this review, recent advances in synthesis and applications of g-CNQDs were summarized and the future challenges as well as opportunities of these g-CNQDs in the chemical and biomedical fields will be highlighted.

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Saliev, Timur. "The Advances in Biomedical Applications of Carbon Nanotubes." C 5, no. 2 (May 23, 2019): 29. http://dx.doi.org/10.3390/c5020029.

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Unique chemical, physical, and biological features of carbon nanotubes make them an ideal candidate for myriad applications in industry and biomedicine. Carbon nanotubes have excellent electrical and thermal conductivity, high biocompatibility, flexibility, resistance to corrosion, nano-size, and a high surface area, which can be tailored and functionalized on demand. This review discusses the progress and main fields of bio-medical applications of carbon nanotubes based on recently-published reports. It encompasses the synthesis of carbon nanotubes and their application for bio-sensing, cancer treatment, hyperthermia induction, antibacterial therapy, and tissue engineering. Other areas of carbon nanotube applications were out of the scope of this review. Special attention has been paid to the problem of the toxicity of carbon nanotubes.

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Wang, Fei, Pan Li, Hoi Ching Chu, and Pik Kwan Lo. "Nucleic Acids and Their Analogues for Biomedical Applications." Biosensors 12, no. 2 (February 4, 2022): 93. http://dx.doi.org/10.3390/bios12020093.

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Nucleic acids are emerging as powerful and functional biomaterials due to their molecular recognition ability, programmability, and ease of synthesis and chemical modification. Various types of nucleic acids have been used as gene regulation tools or therapeutic agents for the treatment of human diseases with genetic disorders. Nucleic acids can also be used to develop sensing platforms for detecting ions, small molecules, proteins, and cells. Their performance can be improved through integration with other organic or inorganic nanomaterials. To further enhance their biological properties, various chemically modified nucleic acid analogues can be generated by modifying their phosphodiester backbone, sugar moiety, nucleobase, or combined sites. Alternatively, using nucleic acids as building blocks for self-assembly of highly ordered nanostructures would enhance their biological stability and cellular uptake efficiency. In this review, we will focus on the development and biomedical applications of structural and functional natural nucleic acids, as well as the chemically modified nucleic acid analogues over the past ten years. The recent progress in the development of functional nanomaterials based on self-assembled DNA-based platforms for gene regulation, biosensing, drug delivery, and therapy will also be presented. We will then summarize with a discussion on the advanced development of nucleic acid research, highlight some of the challenges faced and propose suggestions for further improvement.

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RESIAK, ILONA, and GABRIEL ROKICKI. "Modified polyurethanes for biomedical applications." Polimery 45, no. 09 (September 2000): 592–602. http://dx.doi.org/10.14314/polimery.2000.592.

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Ghadiri, M., W. Chrzanowski, and R. Rohanizadeh. "Biomedical applications of cationic clay minerals." RSC Advances 5, no. 37 (2015): 29467–81. http://dx.doi.org/10.1039/c4ra16945j.

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Delplace, Vianney, and Julien Nicolas. "Degradable vinyl polymers for biomedical applications." Nature Chemistry 7, no. 10 (September 22, 2015): 771–84. http://dx.doi.org/10.1038/nchem.2343.

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BAUM, RUDY M. "Metalloporphyrin Research Makes Strides in Biomedical Applications." Chemical & Engineering News 66, no. 44 (October 31, 1988): 18–22. http://dx.doi.org/10.1021/cen-v066n044.p018.

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Xu, Rui, Yujie Li, Chenyou Zhu, Dongsheng Liu, and Yuhe R. Yang. "Cellular Ingestible DNA Nanostructures for Biomedical Applications." Advanced NanoBiomed Research 3, no. 1 (January 2023): 2370011. http://dx.doi.org/10.1002/anbr.202370011.

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Turcheniuk, Kostiantyn, Rabah Boukherroub, and Sabine Szunerits. "Gold–graphene nanocomposites for sensing and biomedical applications." Journal of Materials Chemistry B 3, no. 21 (2015): 4301–24. http://dx.doi.org/10.1039/c5tb00511f.

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Li, Xiumei, Wanjia Xu, Yue Xin, Jiawei Yuan, Yuancheng Ji, Shengnan Chu, Junqiu Liu, and Quan Luo. "Supramolecular Polymer Nanocomposites for Biomedical Applications." Polymers 13, no. 4 (February 9, 2021): 513. http://dx.doi.org/10.3390/polym13040513.

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Polymer nanocomposites, a class of innovative materials formed by polymer matrixes and nanoscaled fillers (e.g., carbon-based nanomaterials, inorganic/semiconductor nanoparticles, metal/metal-oxide nanoparticles, polymeric nanostructures, etc.), display enhanced mechanical, optoelectrical, magnetic, catalytic, and bio-related characteristics, thereby finding a wide range of applications in the biomedical field. In particular, the concept of supramolecular chemistry has been introduced into polymer nanocomposites, which creates myriad “smart” biomedical materials with unique physicochemical properties and dynamic tunable structures in response to diverse external stimuli. This review aims to provide an overview of the chemical composition, morphological structures, biological functionalities, and reinforced performances of supramolecular polymer nanocomposites. Additionally, recent advances in biomedical applications such as therapeutic delivery, bioimaging, and tissue engineering are also discussed, especially their excellent properties leveraged in the development of multifunctional intelligent biomedical materials.

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Gutiérrez de la Rosa, Sagrario Yadira, Ramiro Muñiz Diaz, Paola Trinidad Villalobos Gutiérrez, Rita Patakfalvi, and Óscar Gutiérrez Coronado. "Functionalized Platinum Nanoparticles with Biomedical Applications." International Journal of Molecular Sciences 23, no. 16 (August 20, 2022): 9404. http://dx.doi.org/10.3390/ijms23169404.

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Functionalized platinum nanoparticles have been of considerable interest in recent research due to their properties and applications, among which they stand out as therapeutic agents. The functionalization of the surfaces of nanoparticles can overcome the limits of medicine by increasing selectivity and thereby reducing the side effects of conventional drugs. With the constant development of nanotechnology in the biomedical field, functionalized platinum nanoparticles have been used to diagnose and treat diseases such as cancer and infections caused by pathogens. This review reports on physical, chemical, and biological methods of obtaining platinum nanoparticles and the advantages and disadvantages of their synthesis. Additionally, applications in the biomedical field that can be utilized once the surfaces of nanoparticles have been functionalized with different bioactive molecules are discussed, among which antibodies, biodegradable polymers, and biomolecules stand out.

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Heimann, Robert B. "Silicon Nitride Ceramics: Structure, Synthesis, Properties, and Biomedical Applications." Materials 16, no. 14 (July 21, 2023): 5142. http://dx.doi.org/10.3390/ma16145142.

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Silicon nitride ceramics excel by superior mechanical, thermal, and chemical properties that render the material suitable for applications in several technologically challenging fields. In addition to high temperature, high stress applications have been implemented in aerospace gas turbines and internal combustion engines as well as in tools for metal manufacturing, forming, and machining. During the past few decades, extensive research has been performed to make silicon nitride suitable for use in a variety of biomedical applications. This contribution discusses the structure–property–application relations of silicon nitride. A comparison with traditional oxide-based ceramics confirms that the advantageous mechanical and biomedical properties of silicon nitride are based on a high proportion of covalent bonds. The present biomedical applications are reviewed here, which include intervertebral spacers, orthopedic and dental implants, antibacterial and antiviral applications, and photonic parts for medical diagnostics.

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Simon, Sohail, Nicole Remaliah Samantha Sibuyi, Adewale Oluwaseun Fadaka, Samantha Meyer, Jamie Josephs, Martin Opiyo Onani, Mervin Meyer, and Abram Madimabe Madiehe. "Biomedical Applications of Plant Extract-Synthesized Silver Nanoparticles." Biomedicines 10, no. 11 (November 2, 2022): 2792. http://dx.doi.org/10.3390/biomedicines10112792.

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Silver nanoparticles (AgNPs) have attracted a lot of interest directed towards biomedical applications due in part to their outstanding anti-microbial activities. However, there have been many health-impacting concerns about their traditional synthesis methods, i.e., the chemical and physical methods. Chemical methods are commonly used and contribute to the overall toxicity of the AgNPs, while the main disadvantages of physical synthesis include high production costs and high energy consumption. The biological methods provide an economical and biocompatible option as they use microorganisms and natural products in the synthesis of AgNPs with exceptional biological properties. Plant extract-based synthesis has received a lot of attention and has been shown to resolve the limitations associated with chemical and physical methods. AgNPs synthesized using plant extracts provide a safe, cost-effective, and environment-friendly approach that produces biocompatible AgNPs with enhanced properties for use in a wide range of applications. The review focused on the use of plant-synthesized AgNPs in various biomedical applications as anti-microbial, anti-cancer, anti-inflammatory, and drug-delivery agents. The versatility and potential use of green AgNPs in the bio-medicinal sector provides an innovative alternative that can overcome the limitations of traditional systems. Thus proving green nanotechnology to be the future for medicine with continuous progress towards a healthier and safer environment by forming nanomaterials that are low- or non-toxic using a sustainable approach.

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