Relevant bibliographies by topics / Biomaterials for orthopedic applications / Dissertations / Theses
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Dissertations / Theses on the topic 'Biomaterials for orthopedic applications'

Author: Grafiati
Published: 6 September 2023

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1

Vidal, Girona Elia. "Development of metallic functionalized biomaterials with low elastic modulus for orthopedic applications." Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2021. http://hdl.handle.net/10803/671888.

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Titanium (Ti) and Ti alloys have been used for decades for bone implants and prostheses due to its mechanical reliability and good biocompatibility. However, implant-related infections, lack of osseointegration with the surrounding bone, and the mismatch of mechanical properties between implant and bone, remain among the leading reasons for implant failure. In the present PhD thesis, two strategies have been studied to increase implant viability: fabrication of porous Ti structures and surface functionalization. The stiffness mismatch between titanium implant and bone can cause significant bo
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2

Clem, William Charles. "Mesenchymal stem cell interaction with nanonstructured biomaterials for orthopaedic applications." Birmingham, Ala. : University of Alabama at Birmingham, 2008. https://www.mhsl.uab.edu/dt/2009r/clem.pdf.

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Thesis (Ph. D.)--University of Alabama at Birmingham, 2008.<br>Additional advisors: Yogesh K. Vohra, Xu Feng, Jack E. Lemons, Timothy M. Wick. Description based on contents viewed July 8, 2009; title from PDF t.p. Includes bibliographical references.
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3

Smith, Michael E. "Method Development for On-Site Air Quality Analysis and Design of Hydrogen Sensors for Orthopedic Applications." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1583999801696302.

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4

Raghuraman, Kapil. "Synthesis and Evaluation of a Zn-Bioactive Glass Series to Prevent Post-Operative Infections in Craniofacial Applications." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1525241500626456.

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5

Ahn, Edward Sun 1972. "Nanostructured apatites as orthopedic biomaterials." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/8627.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2001.<br>Includes bibliographical references.<br>Historically, using suitable mechanical replacements for bone has been a priority in designing permanent, load-bearing orthopedic implants. As a result, the biomaterials used in these implants have been largely limited to bioinert titanium-based alloys, as well as to polycrystalline alumina and zirconia ceramics. However, analysis of implants incorporating these traditional biomaterials indicated that most failures involved an unstable implant-tissue interface
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6

Devlin, Sean M. "Improving Degradable Biomaterials for Orthopedic Fixation Devices." Diss., Temple University Libraries, 2016. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/394989.

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Bioengineering<br>Ph.D.<br>Current degradable orthopedic fixation devices do not typically facilitate tissue integration during healing. Proposed here is a novel combination of processing methods to enhance the tissue integration capability of degradable thermoplastics used in temporary orthopedic fixation devices. The provision of open pores in devices used to affix reconstructed hard tissues would allow for local cells to infiltrate during the healing process. Any openly porous structure is inherently weakened in comparison to its monolithic peers (i.e. decreased relative bulk modulus), such that
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7

Ensing, Geert Tone. "Prevention and treatment of biomaterial related infection in orthopedics a study of application of ultrasound and of antibiotic release /." [S.l. : [Groningen : s.n.] ; University Library Groningen] [Host], 2006. http://irs.ub.rug.nl/ppn/291344038.

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8

Gianforcaro, Anthony L. "Improvement Of Biodegradable Biomaterials For Use In Orthopedic Fixation Devices." Master's thesis, Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/599834.

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Bioengineering<br>M.S.<br>Current orthopedic internal fixation devices, such as pins and screws, are typically made from metals and have a long list of complications associated with them. Most notably, complications such as infection or decreased wound healing arise from revisional surgeries needed to remove the used hardware. A new class of fixation devices is being produced from biodegradable biomaterials to eliminate the need for revisional surgery by being naturally broken down in the body. While currently available polymers lack the necessary mechanical properties to match bone strength,
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9

Wong, Kai-lun, and 黄棨麟. "Strontium-substituted hydroxyapatite reinforced polyetheretherketone biomaterials in orthopaedic implants." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42182505.

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10

Wong, Kai-lun. "Strontium-substituted hydroxyapatite reinforced polyetheretherketone biomaterials in orthopaedic implants." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42182505.

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11

López, Alejandro. "Injectable Biomaterials for Spinal Applications." Doctoral thesis, Uppsala universitet, Institutionen för teknikvetenskaper, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-215606.

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The use of injectable biomaterials is growing as the demands for minimally invasive procedures, and more easily applicable implants become higher, but their availability is still limited due to the difficulties associated to their design. Each year, more than 700,000 vertebral compression fractures (VCF’s) are reported in the US and 500,000 VCF’s in Europe due to primary osteoporosis only. VCF’s can compromise the delicacy of the spinal canal and also cause back pain, which affects the patient’s quality of life. Vertebroplasty was developed in the 80’s, and has proven to be a safe minimally in
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12

Lawson, McKinley C. "Structure-function relationships of polymerizable vancomycin derivatives for the antimicrobial surface modification of orthopedic biomaterials." Connect to online resource, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3315775.

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13

Yeung, Che-yan, and 楊芷茵. "Antibacterial properties and biocompatibility of novel peptide incorporated titanium alloy biomaterials for orthopaedic implants." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hdl.handle.net/10722/197133.

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14

Lahiri, Debrupa. "Hydroxyapatite-Nanotube Composites and Coatings for Orthopedic Applications." FIU Digital Commons, 2011. http://digitalcommons.fiu.edu/etd/444.

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Hydroxyapatite (HA) has received wide attention in orthopedics, due to its biocompatibility and osseointegration ability. Despite these advantages, the brittle nature and low fracture toughness of HA often results in rapid wear and premature fracture of implant. Hence, there is a need to improve the fracture toughness and wear resistance of HA without compromising its biocompatibility. The aim of the current research is to explore the potential of nanotubes as reinforcement to HA for orthopedic implants. HA- 4 wt.% carbon nanotube (CNT) composites and coatings are synthesized by spark plasma s
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15

Boroujeni, Nariman Mansouri. "Monetite Cement Composites for Orthopedic and Dental Applications." University of Toledo / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1341378401.

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16

GOLOB, SAMUEL. "INNOVATIVE ANTIBACTERIAL SYSTEMS FOR ORTHOPEDIC AND TRAUMATOLOGY APPLICATIONS." Doctoral thesis, Università degli Studi di Trieste, 2016. http://hdl.handle.net/11368/2907984.

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Le infezioni ortopediche sono una problematica devastante che colpisce il 2% dei pazienti che si sottopongono ad interventi di sostituzione articolari. Il lavoro di ricerca di questo dottorato ha come scopo l'individuazione di sistemi tecnologicamente innovativi per la profilassi e la cura di tali infezioni.
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17

Cai, Yanling. "Titanium Dioxide Photocatalysis in Biomaterials Applications." Doctoral thesis, Uppsala universitet, Nanoteknologi och funktionella material, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-160634.

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Despite extensive preventative efforts, the problem of controlling infections associated with biomedical materials persists. Bacteria tend to colonize on biocompatible materials and form biofilms; thus, novel biomaterials with antibacterial properties are of great interest. In this thesis, titanium dioxide (TiO2)-associated photocatalysis under ultraviolet (UV) irradiation was investigated as a strategy for developing bioactivity and antibacterial properties on biomaterials. Although much of the work was specifically directed towards dental materials, the results presented are applicable to a
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18

Heath, Daniel Edward. "Methacrylic Terpolymer Biomaterials for Cardiovascular Applications." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1276802114.

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19

Miao, Tianxin. "Smart Synthetic Biomaterials for Therapeutic Applications." ScholarWorks @ UVM, 2016. http://scholarworks.uvm.edu/graddis/610.

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In the field of biomaterials, naturally-derived and synthetic polymers are utilized individually or in combination with each other, to create bio-inspired or biomimetic materials for various bioengineering applications, including drug delivery and tissue engineering. Natural polymers, such as proteins and polysaccharides, are advantageous due to low or non-toxicity, sustainable resources, innocuous byproducts, and cell-instructive properties. Synthetic polymers offer a variety of controlled chemical and physical characteristics, with enhanced mechanical properties. Together, natural and synthe
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20

TARUSHA, LORENA. "Novel nanostructured biomaterials for biomedical applications." Doctoral thesis, Università degli Studi di Trieste, 2016. http://hdl.handle.net/11368/2908088.

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The research activity reported in this thesis was focused on bottom-up design, production and characterization of biomaterials in the form of medical devices for biomedical applications. More specifically, both a biomaterial for anastomosis after colorectal cancer resection, and a biomaterial for chronic non-healing wounds have been designed and developed, by exploiting the same manufacturing strategy. In the first part of the work, the research has been mainly aimed to obtain a device for preventing the leakage of the anastomosis following surgical treatment of colorectal cancer. The anastomo
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21

Chan, Yee-loi. "Surface modification of NiTi for long term orthopedic applications." Click to view the E-thesis via HKUTO, 2007. http://sunzi.lib.hku.hk/HKUTO/record/B39557406.

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22

Chan, Yee-loi, and 陳以來. "Surface modification of NiTi for long term orthopedic applications." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B39557406.

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23

Blanquer, Jerez Andreu. "Biocompatibility of new biomaterials for orthopaedic applications." Doctoral thesis, Universitat Autònoma de Barcelona, 2016. http://hdl.handle.net/10803/386500.

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L’ús de materials biocompatibles ha assolit una importància creixent en aplicacions ortopèdiques i quirúrgiques, degut a l’envelliment de la població. Els aliatges metàl·lics que s’empren actualment en medicina presenten propietats físiques i mecàniques diferents a les de l’os humà, incrementant la probabilitat de pèrdua de l’implant. Per aquesta raó, s’estan desenvolupant nous aliatges metàl·lics amb millors propietats. En aquest sentit, la present tesi té com objectiu l’anàlisi de la biocompatibilitat de nous aliatges pel seu ús en implants ortopèdics. En primer lloc, s’ha demostrat la bioco
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24

Venturato, Andrea. "2D and 3D applications of polymeric biomaterials." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31045.

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The field of biomaterials has seen huge development over the past decade with enormous efforts invested in discovering materials with improved biocompatibility, application and versatility. Polymers can display many properties that make them ideal biomaterials, such as their potential flexibility, low weight, low cost and biodegradability. Moreover, they can be prepared in a wide variety of compositions and forms and be readily fabricated into various shapes and structures. Polymer microarrays represent an efficient high-throughput platform for the screening and discovery of new materials comp
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25

Khurshid, Z., S. Najeeb, M. S. Zafar, and Farshid Sefat. "Advanced Dental Biomaterials: Chemistry, Manipulation and Applications." Elsevier, 2019. http://hdl.handle.net/10454/18383.

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No<br>Advanced Dental Biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. The book can be used by both an experienced researcher/clinician learning about other biomaterials or applications that may be applicable to their current research or as a guide for a new entrant into the field who needs to gain an understanding of the primary challenges, opportunities, most relevant biomaterials, and key applications in dentistry.
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26

Zhao, Weiyu. "Development of Functionalized Biomaterials for Biomedical Applications." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1594988786199951.

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27

Zhang, Rui. "Converting macroalgal biomass into biomaterials and applications." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20122.

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This thesis focused on the extraction of value-added biomaterials from brown seaweed and the potential applications of the extracted biomaterials as well as an analysis of the prospects of building a general bio-refinery pathway for brown seaweed. Microwave assisted extraction (MAE) was used as an innovative extraction method for phlorotannins extraction from brown seaweed. Comparison of the extraction efficiency of phlorotannins by means of MAE and conventional solid–liquid extraction from three species of brown seaweeds determined that an optimized MAE protocol increased yields by 70%. The a
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28

Costanza, Frankie. "Design, Synthesis and Applications of Polymer Biomaterials." Scholar Commons, 2015. https://scholarcommons.usf.edu/etd/5462.

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The emergence of antibiotic resistant bacteria has prompted the research into novel kinds of antibacterial small molecules and polymers. Nature has solved this issue with the use of cationic antimicrobial peptides, which act as nonspecific antibiotics against invading species. Herein, we have tried to mimic this general mechanism in a biocompatible and biodegradable polymer micelle based on the polymerization of naturally occurring amino acids lysine and phenylalanine linked to a PEG tether. This amphiphilic structure allows for the spontaneous collapse into stable nanoparticles in solution, w
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RUINI, FRANCESCA. "Chitosan based biomaterials: soft tissue engineering applications." Doctoral thesis, Politecnico di Torino, 2015. http://hdl.handle.net/11583/2602188.

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In recent years, considerable attention has been given to chitosan (CS)-based biomaterials and their applications in the field of soft tissue engineering (TE). CS is a glycosaminoglycan derived from chitin, the primary structural polymer in crustacean exoskeletons. CS is biocompatible, biodegradable, easily formed into various structures (i.e. sponges, nanofibers and films) under mild processing conditions and can be chemically modified through graft copolymerization and crosslinking. However, the rapid degradation of CS and its low mechanical strength are concerns that may limit its use in cl
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Rubini, Katia <1966&gt. "Biomaterials for osteoarticular applications: role of functionalization." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2022. http://amsdottorato.unibo.it/10077/1/Rubini_Katia_submitted-1-140.pdf.

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This work was focused on the development of functionalized materials with potential applications for the substitution/repair of damaged tissues. The materials utilized as substrates were calcium orthophosphates, namely hydroxyapatite, β-tricalcium phosphate, monetite and brushite, and gelatin films. This choice was based on a biomimetic strategy: the inorganic component of the hard tissues of vertebrates is a basic calcium phosphate similar to synthetic hydroxyapatite, and gelatin is a degradation product of the main proteic component of the human body, collagen. Functionalization of calcium
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31

SCOGNAMIGLIO, FRANCESCA. "Nano-engineered adhesive biomaterials for biomedical applications." Doctoral thesis, Università degli Studi di Trieste, 2016. http://hdl.handle.net/11368/2907994.

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This thesis is focused on the development of adhesive systems for biomedical applications and has been carried out in the framework of the European Project “AnastomoSEAL” (EU-FP7). Within this project, a bioactive membrane based on polysaccharides was developed for the prevention of anastomotic leakage (AL) after colo-rectal cancer (CRC) resection. The membrane was designed to be wrapped around the intestinal tissue in order to stimulate the healing of the surgical wound, thus accelerating its closure. The main components of the system were the two polysaccharides alginate and hyaluronan (HA),
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Rivera, Miguel A. "Powder processing of porous polysulfone for orthopedic and dental applications." Thesis, Georgia Institute of Technology, 1985. http://hdl.handle.net/1853/10288.

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33

Benezra, Valarie Ilene 1971. "Electron microscopic investigation of interfaces in materials for orthopedic applications." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/9690.

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Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 1998.<br>Includes bibliographical references (leaves 214-230).<br>About 250,000 people undergo knee and hip arthroplasty each year in North America alone, with hundreds of thousands more receiving joints over the rest of the world. Two factors are key to the success of these implants: first, the quality of attachment of the prosthetic joint to the patient's bone, and second, the low generation of wear particles as the components of the prosthesis articulate against each other. This thesis is a st
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34

Yang, Xia. "Multi-functional Hyaluronan Based Biomaterials for Biomedical Applications." Doctoral thesis, Uppsala universitet, Polymerkemi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-224371.

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This thesis presents strategies for constructing multi-functional biomaterials based on hyaluronan (HA) derivatives for various biomedical applications, such as drug delivery, tissue regeneration, and imaging biomaterials. The aim of this study is to improve the functionalities of HA biomaterials as well as simplify the preparation procedures.  Native HA polymer contains D-glucuronic acid residue with a carboxyl group per disaccharide unit that can be easily modified by carbodiimide-mediated amidation reaction. Therefore, we have designed a series of orthogonal groups (hydrazide, carbazate, al
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Banwell, Eleanor Frances. "Self-assembling fibrous biomaterials for cell-biology applications." Thesis, University of Bristol, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441317.

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36

Hodgkinson, Tom. "Silk fibroin biomaterials for skin tissue engineering applications." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/silk-fibroin-biomaterials-for-skin-tissue-engineering-applications(75958c4c-dacf-466f-ae6f-e8c9bb7c20b8).html.

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The limited reparative capacity of the skin and the inadequacy of conventional treatments have necessitated the development of tissue engineered skin substitutes. Several substitutes, including Integra Dermal Regeneration Template, are finding increasingly widespread application in the treatment of acute and chronic wounds. To date, these substitutes are unable to fully recreate the functionality and aesthetics of skin prior to injury. This thesis applied an integrated approach combining solution preparation, material fabrication control and biological testing to investigate electrospun silk f
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Ma, Weili. "Engineered Biomaterials for Human Neural Stem Cell Applications." Diss., Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/594172.

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Bioengineering<br>Ph.D.<br>Within the last decade, neurodegenerative diseases such as Alzheimer’s and Parkinson’s have emerged as one of the top 5 leading causes of death globally, and there is currently no cure. All neurodegenerative diseases lead to loss of the functional cells in the nervous system, the neurons. One therapeutic approach is to replace the damaged and lost neurons with new, healthy neurons. Unfortunately, this is a difficult endeavor since mature neurons are not capable of cell division. Instead, researchers are turning to neural stem cells, which are able to self-renew and b
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38

Curcio, Mariangela. "Thin coatings of biomaterials for hard tissue applications." Doctoral thesis, Universita degli studi di Salerno, 2018. http://hdl.handle.net/10556/3055.

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2016 - 2017<br>The goal of the present study is the production of new-generation coatings suitable for hard tissue implants, intended to decrease the healing time, limit infections and rejections and improve patients' life quality. Materials designed for implant coatings are mainly bioactive ceramics. Belonging to this class of biomaterials, hydroxyapatite (HAp), bioglass (BG) and glass-ceramic (BGC) are indicated for application in hard tissue replacement and regeneration. However the use of each one has strengths and weaknesses; therefore the attention has been focused on their peculia
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Perin, Danilo. "Biomaterials for biotechnological applications: synthesis and activity evaluations." Doctoral thesis, Università degli studi di Trieste, 2010. http://hdl.handle.net/10077/3518.

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2008/2009<br>A biomaterial was defined as any non-living material used in a medical device that interacts with biological systems. Many different applications involve the use of biomaterials: pharmacology, controlled drug release, extracorporeal devices (contact lens, emodialysis devices, cardiopulmonary bypass oxygenators), artificial prostheses. One of the most interesting biomaterials application regards the release of nucleic acids and their derivatives as therapeutic agents. These molecules, defined as “nucleic acid base drugs” (NABDs), allows highly targeted cellular metabolism modificat
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40

Flamant, Quentin. "Surface modification of zirconia-based bioceramics for orthopedic and dental applications." Doctoral thesis, Universitat Politècnica de Catalunya, 2016. http://hdl.handle.net/10803/436899.

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Debido a sus excelentes propiedades mecánicas y una excelente biocompatibilidad, el uso de las cerámicas de base de circona en aplicaciones dentales y ortopédicas ha crecido rápidamente durante las últimas décadas. Sin embargo, tanto la alúmina como la circona son bioinertes, lo cual dificulta su implantación en contacto directo con el hueso. Además, las infecciones siguen siendo una de las principales causas de fallo de implantes. Para resolver ambos problemas, se requiere un mejor diseño de la superficie: en particular, una topografía adecuada puede promover la osteointegración y limitar la
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Koju, Naresh. "Smart Piezoelectric Calcium Phosphates for Orthopedic, Spinal-fusion and Dental Applications." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1524047236280822.

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Fang, Liming. "Processing of HA/UHMWPE for orthopaedic applications /." View abstract or full-text, 2003. http://library.ust.hk/cgi/db/thesis.pl?MECH%202003%20FANG.

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Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2003.<br>Includes bibliographical references (leaves 128-138). Also available in electronic version. Access restricted to campus users.
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Woo, Gregory Lu-Yuen. "Development of novel biodegradable antimicrobial polymers for biomaterials applications." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0001/MQ40915.pdf.

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44

Wang, Ling. "Syntheses and applications of bisphosphonate-based biomaterials and nanomaterials /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?CHEM%202007%20WANG.

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45

Zheng, Jukuan. "Synthesis and Modification of Biomaterials for Tissue Engineering Applications." University of Akron / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=akron1427581327.

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46

Fraioli, Roberta. "Functionalization of titanium with integrin-selective ligands for orthopedic and dental applications." Doctoral thesis, Universitat Politècnica de Catalunya, 2016. http://hdl.handle.net/10803/404303.

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Despite being biocompatible and with adequate mechanical properties for application as a bone replacement material, titanium lacks osteoinductive capacity, i.e. it supports new bone growth on its surface but does not foster its formation. This may lead to failure of the implant due to poor osseointegration. Together with infection, this is in fact the main cause of failure of orthopedic and dental implants. Therefore, this thesis explores the possibility to convert titanium surface into a bioactive substrate, which is actively capable of influencing cell fate in vitro and enhance implant osteo
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47

Nysjö, Johan. "Interactive 3D Image Analysis for Cranio-Maxillofacial Surgery Planning and Orthopedic Applications." Doctoral thesis, Uppsala universitet, Avdelningen för visuell information och interaktion, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-301180.

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Modern medical imaging devices are able to generate highly detailed three-dimensional (3D) images of the skeleton. Computerized image processing and analysis methods, combined with real-time volume visualization techniques, can greatly facilitate the interpretation of such images and are increasingly used in surgical planning to aid reconstruction of the skeleton after trauma or disease. Two key challenges are to accurately separate (segment) bone structures or cavities of interest from the rest of the image and to interact with the 3D data in an efficient way. This thesis presents efficient a
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48

Hassan, S. M. Mahmudul. "Development of Novel High Strength Composite Calcium Phosphate Cement for Orthopedic Applications." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1533212629435654.

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49

Fan, Dongmei. "Mesoporous silicon/biopolymer composities for orthopedic tissue engineering and drug delivery applications." [Fort Worth, Tex.] : Texas Christian University, 2008. http://etd.tcu.edu/etdfiles/available/etd-12192008-090502/unrestricted/fan.pdf.

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50

Zhang, Xi. "Polymer composites incorporating engineered electrospun fibres : flexible design and novel properties for biomedical applications." Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/30904.

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Due to their unique structure and flexible choice of materials, electrospun degradable and biocompatible polymer fibres are considered to be extremely suitable for biomedical applications such as tissue engineering and drug delivery, either on their own or integrated within composites. Conventional electrospun fibre composites are typically based on non-woven mats and therefore limited to simple-curved geometries (films, membranes, etc.). For aqueous composites such as hydrogels, the hydrophobicity of the materials sometimes prohibits fibres to be easily integrated or distributed in these comp
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