Academic literature on the topic 'Biological Science - Nanomaterials'
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Journal articles on the topic "Biological Science - Nanomaterials"
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Babuska, Vaclav, Phanindra Babu Kasi, Petra Chocholata, Lucie Wiesnerova, Jana Dvorakova, Radana Vrzakova, Anna Nekleionova, Lukas Landsmann, and Vlastimil Kulda. "Nanomaterials in Bone Regeneration." Applied Sciences 12, no. 13 (July 5, 2022): 6793. http://dx.doi.org/10.3390/app12136793.
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Nanomaterials are promising in the development of innovative therapeutic options that include tissue and organ replacement, as well as bone repair and regeneration. The expansion of new nanoscaled biomaterials is based on progress in the field of nanotechnologies, material sciences, and biomedicine. In recent decades, nanomaterial systems have bridged the line between the synthetic and natural worlds, leading to the emergence of a new science called nanomaterial design for biological applications. Nanomaterials replicating bone properties and providing unique functions help in bone tissue engineering. This review article is focused on nanomaterials utilized in or being explored for the purpose of bone repair and regeneration. After a brief overview of bone biology, including a description of bone cells, matrix, and development, nanostructured materials and different types of nanoparticles are discussed in detail.
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Wang, Jiali, Guo Zhao, Liya Feng, and Shaowen Chen. "Metallic Nanomaterials with Biomedical Applications." Metals 12, no. 12 (December 12, 2022): 2133. http://dx.doi.org/10.3390/met12122133.
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Metallic nanomaterials have attracted extensive attention in various fields due to their photocatalytic, photosensitive, thermal conducting, electrical conducting and semiconducting properties. Among all these fields, metallic nanomaterials are of particular importance in biomedical sensing for the detection of different analytes, such as proteins, toxins, metal ions, nucleotides, anions and saccharides. However, many problems remain to be solved, such as the synthesis method and modification of target metallic nanoparticles, inadequate sensitivity and stability in biomedical sensing and the biological toxicity brought by metallic nanomaterials. Thus, this Special Issue aims to collect research or review articles focused on electrochemical biosensing, such as metallic nanomaterial-based electrochemical sensors and biosensors, metallic oxide-modified electrodes, biological sensing based on metallic nanomaterials, metallic nanomaterial-based biological sensing devices and chemometrics for metallic nanomaterial-based biological sensing. Meanwhile, studies related to the synthesis and characterization of metallic nanomaterials are also welcome, and both experimental and theoretical studies are welcome for contribution as well.
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Vianello, Fabio, Alessandro Cecconello, and Massimiliano Magro. "Toward the Specificity of Bare Nanomaterial Surfaces for Protein Corona Formation." International Journal of Molecular Sciences 22, no. 14 (July 16, 2021): 7625. http://dx.doi.org/10.3390/ijms22147625.
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Aiming at creating smart nanomaterials for biomedical applications, nanotechnology aspires to develop a new generation of nanomaterials with the ability to recognize different biological components in a complex environment. It is common opinion that nanomaterials must be coated with organic or inorganic layers as a mandatory prerequisite for applications in biological systems. Thus, it is the nanomaterial surface coating that predominantly controls the nanomaterial fate in the biological environment. In the last decades, interdisciplinary studies involving not only life sciences, but all branches of scientific research, provided hints for obtaining uncoated inorganic materials able to interact with biological systems with high complexity and selectivity. Herein, the fragmentary literature on the interactions between bare abiotic materials and biological components is reviewed. Moreover, the most relevant examples of selective binding and the conceptualization of the general principles behind recognition mechanisms were provided. Nanoparticle features, such as crystalline facets, density and distribution of surface chemical groups, and surface roughness and topography were encompassed for deepening the comprehension of the general concept of recognition patterns.
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Xie, Jiani, Huilun Li, Tairan Zhang, Bokai Song, Xinhui Wang, and Zhanjun Gu. "Recent Advances in ZnO Nanomaterial-Mediated Biological Applications and Action Mechanisms." Nanomaterials 13, no. 9 (April 27, 2023): 1500. http://dx.doi.org/10.3390/nano13091500.
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In recent years, with the deepening research, metal zinc oxide (ZnO) nanomaterials have become a popular research object in the biological field, particularly in biomedicine and food safety, which is attributed to their unique physicochemical properties such as high surface area and volume ratio, luminescence effect, surface characteristics and biological activities. Herein, this review provides a detailed overview of the ZnO nanomaterial-mediated biological applications that involve anti-bacterial, anti-tumor, anti-inflammation, skin care, biological imaging and food packaging applications. Importantly, the corresponding action mechanisms of ZnO nanomaterials are pointed. Additionally, the structure and structure-dependent physicochemical properties, the common synthesis methods and the biosafety of ZnO nanoparticles are revealed in brief. Finally, the significance and future challenges of ZnO nanomaterial applications are concluded.
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Kladko, Daniil V., Aleksandra S. Falchevskaya, Nikita S. Serov, and Artur Y. Prilepskii. "Nanomaterial Shape Influence on Cell Behavior." International Journal of Molecular Sciences 22, no. 10 (May 17, 2021): 5266. http://dx.doi.org/10.3390/ijms22105266.
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Nanomaterials are proven to affect the biological activity of mammalian and microbial cells profoundly. Despite this fact, only surface chemistry, charge, and area are often linked to these phenomena. Moreover, most attention in this field is directed exclusively at nanomaterial cytotoxicity. At the same time, there is a large body of studies showing the influence of nanomaterials on cellular metabolism, proliferation, differentiation, reprogramming, gene transfer, and many other processes. Furthermore, it has been revealed that in all these cases, the shape of the nanomaterial plays a crucial role. In this paper, the mechanisms of nanomaterials shape control, approaches toward its synthesis, and the influence of nanomaterial shape on various biological activities of mammalian and microbial cells, such as proliferation, differentiation, and metabolism, as well as the prospects of this emerging field, are reviewed.
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S, Lakshmana Prabu. "Emerging Approaches and Perception of Toxicity Assessment in Nanomaterials." Bioequivalence & Bioavailability International Journal 6, no. 1 (February 8, 2022): 1–5. http://dx.doi.org/10.23880/beba-16000168.
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In the 21st century, nanotechnology, an interdisciplinary research has become an innovative field and made a new revolution in science and technology. Its unique properties has led an extensive research interest among the researchers and utilized in various fields including biomedical applications. Increased use of nanomaterials in health sciences and medicine aroused a global concern on the biological response, effectiveness, and toxicity of these materials. Therefore, it has become imperative in studying the toxicity of nanomaterial (Nanotoxicology) in therapeutic applications. The main aim of nanotoxicological studies is to determine the toxic/hazardous effects of nanomaterials on humans and to the environment. The toxicity of the nanomaterials depends on various physicochemical properties such as size, shape, surface area, surface chemistry, concentration and several others parameters. Nanomaterials have shown higher toxicity particularly in inhalation studies, hence stringent regulations are made for nanotechnology products to ensure the safety of the products. There are few approaches to overcome these toxicities and improve its therapeutic efficacy and safety. Hence development of nanotechnology should occur on par with risk assessment to identify and subsequently avoid possible dangers in the near future. This article highlights on the different nanomaterials, their unique properties and frameworks for assessing the toxicity of nanomaterials.
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Cerpa-Naranjo, Arisbel, Javier Pérez-Piñeiro, Pablo Navajas-Chocarro, Mariana P. Arce, Isabel Lado-Touriño, Niurka Barrios-Bermúdez, Rodrigo Moreno, and María Luisa Rojas-Cervantes. "Rheological Properties of Different Graphene Nanomaterials in Biological Media." Materials 15, no. 10 (May 18, 2022): 3593. http://dx.doi.org/10.3390/ma15103593.
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Carbon nanomaterials have received increased attention in the last few years due to their potential applications in several areas. In medicine, for example, these nanomaterials could be used as contrast agents, drug transporters, and tissue regenerators or in gene therapy. This makes it necessary to know the behavior of carbon nanomaterials in biological media to assure good fluidity and the absence of deleterious effects on human health. In this work, the rheological characterization of different graphene nanomaterials in fetal bovine serum and other fluids, such as bovine serum albumin and water, is studied using rotational and microfluidic chip rheometry. Graphene oxide, graphene nanoplatelets, and expanded graphene oxide at concentrations between 1 and 3 mg/mL and temperatures in the 25–40 °C range were used. The suspensions were also characterized by transmission and scanning electron microscopy and atomic force microscopy, and the results show a high tendency to aggregation and reveals that there is a protein–nanomaterial interaction. Although rotational rheometry is customarily used, it cannot provide reliable measurements in low viscosity samples, showing an apparent shear thickening, whereas capillary viscometers need transparent samples; therefore, microfluidic technology appears to be a suitable method to measure low viscosity, non-transparent Newtonian fluids, as it is able to determine small variations in viscosity. No significant changes in viscosity are found within the solid concentration range studied but it decreases between 1.1 and 0.6 mPa·s when the temperature raises from 25 to 40 °C.
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Rónavári, Andrea, Nóra Igaz, Dóra I. Adamecz, Bettina Szerencsés, Csaba Molnar, Zoltán Kónya, Ilona Pfeiffer, and Monika Kiricsi. "Green Silver and Gold Nanoparticles: Biological Synthesis Approaches and Potentials for Biomedical Applications." Molecules 26, no. 4 (February 5, 2021): 844. http://dx.doi.org/10.3390/molecules26040844.
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The nanomaterial industry generates gigantic quantities of metal-based nanomaterials for various technological and biomedical applications; however, concomitantly, it places a massive burden on the environment by utilizing toxic chemicals for the production process and leaving hazardous waste materials behind. Moreover, the employed, often unpleasant chemicals can affect the biocompatibility of the generated particles and severely restrict their application possibilities. On these grounds, green synthetic approaches have emerged, offering eco-friendly, sustainable, nature-derived alternative production methods, thus attenuating the ecological footprint of the nanomaterial industry. In the last decade, a plethora of biological materials has been tested to probe their suitability for nanomaterial synthesis. Although most of these approaches were successful, a large body of evidence indicates that the green material or entity used for the production would substantially define the physical and chemical properties and as a consequence, the biological activities of the obtained nanomaterials. The present review provides a comprehensive collection of the most recent green methodologies, surveys the major nanoparticle characterization techniques and screens the effects triggered by the obtained nanomaterials in various living systems to give an impression on the biomedical potential of green synthesized silver and gold nanoparticles.
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García-Álvarez, Rafaela, and María Vallet-Regí. "Hard and Soft Protein Corona of Nanomaterials: Analysis and Relevance." Nanomaterials 11, no. 4 (March 31, 2021): 888. http://dx.doi.org/10.3390/nano11040888.
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Upon contact with a biological milieu, nanomaterials tend to interact with biomolecules present in the media, especially proteins, leading to the formation of the so-called “protein corona”. As a result of these nanomaterial–protein interactions, the bio-identity of the nanomaterial is altered, which is translated into modifications of its behavior, fate, and pharmacological profile. For biomedical applications, it is fundamental to understand the biological behavior of nanomaterials prior to any clinical translation. For these reasons, during the last decade, numerous publications have been focused on the investigation of the protein corona of many different types of nanomaterials. Interestingly, it has been demonstrated that the structure of the protein corona can be divided into hard and soft corona, depending on the affinity of the proteins for the nanoparticle surface. In the present document, we explore the differences between these two protein coronas, review the analysis techniques used for their assessment, and reflect on their relevance for medical purposes.
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Abu-Salah, Khalid, Salman A. Alrokyan, Muhammad Naziruddin Khan, and Anees Ahmad Ansari. "Nanomaterials as Analytical Tools for Genosensors." Sensors 10, no. 1 (January 26, 2010): 963–93. http://dx.doi.org/10.3390/s100100963.
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Nanomaterials are being increasingly used for the development of electrochemical DNA biosensors, due to the unique electrocatalytic properties found in nanoscale materials. They offer excellent prospects for interfacing biological recognition events with electronic signal transduction and for designing a new generation of bioelectronic devices exhibiting novel functions. In particular, nanomaterials such as noble metal nanoparticles (Au, Pt), carbon nanotubes (CNTs), magnetic nanoparticles, quantum dots and metal oxide nanoparticles have been actively investigated for their applications in DNA biosensors, which have become a new interdisciplinary frontier between biological detection and material science. In this article, we address some of the main advances in this field over the past few years, discussing the issues and challenges with the aim of stimulating a broader interest in developing nanomaterial-based biosensors and improving their applications in disease diagnosis and food safety examination.
Dissertations / Theses on the topic "Biological Science - Nanomaterials"
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Murdock, Richard Craig. "RADIO FREQUENCY CONTROLLED STIMULATION OF INTRACELLULAR GOLD OR SILVER NANOPARTICLE CONJUGATES FOR USE AS POTENTIAL SENSORS OR MODULATORS OF BIOLOGICAL FUNCTION." Wright State University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=wright1277753458.
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Pecoraro, Roberta. "Toxicity evaluation of new engineered nanomaterials in model organisms." Doctoral thesis, Università di Catania, 2017. http://hdl.handle.net/10761/3998.
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According to the definition adopted by European Commission in 2011 a nanomaterial (NM) is a natural, incidental or manufactured material containing particles, in an unbound state or as an aggregate or as an agglomerate and where, for 50% or more of the particles in the number size distribution, one or more external dimensions is in the size range 1 nm-100 nm (European Commission, 2011/696/EU).
NM exhibit peculiar characteristics (e.g. small size, large surface area to mass ratio, shape, surface charge, reactive surface groups, state of agglomeration) that confer them properties substantially different from those of the bulk particles of the same composition.
Due to their widespread use in the consumer and industrial products, NMs can be released into the environment and it has been raised concern of the scientists about this question (Royal Society and the Royal Academy of Engineering, 2004).
The effects that NMs have on aquatic organisms depend on their characteristics influenced by environmental parameters. NMs enter the aquatic organisms mainly through the epithelial surfaces (such as gills, skin) or direct ingestion (Moore, 2006).
After crossing the cell membrane, NMs may be stored in vesicles, mitochondria and additional organelles within epithelial cells. They may generate reactive oxygen species, oxidative stress, cytotoxicity, apoptosis and necrosis (Oberdörster et al., 2005).
Ecotoxicological tests of NMs should first consider the behaviour of NMs in the aquatic environment and the conditions that may influence aggregation state. For example, some NMs are almost impossible to disperse in water by physical methods such as sonication or stirring and may require the use of a dispersing agent. The choice of dispersant is problematic since some of the best dispersants from a chemistry point of view are also toxic to organisms.
The potential for NMs to cause oxidative injury in fish and invertebrates remains controversial. Bar-Ilan et al., 2009 showed that silver nanoparticles (AgNPs) induced almost 100% mortality in larvae of Danio rerio after acute exposure and a variety of embryonic morphological malformations were observed.
A study showed that gold nanoparticles (AuNPs) are non toxic at the employed concentrations and do not cause obvious abnormalities in developing zebrafish embryos (Asharani et al., 2010).
Zhu et al. (2009) observed effects on mortality and immobility on D. magna in the case of titanium nanoparticles (TiO2NPs) nanoparticles smaller than 20 nm.
Currently there is a lack of knowledge about long-term risks and potential mechanisms of toxicity of NMs; the industrial-scale application of engineered nanomaterials in many areas of daily life raises the question of the security of these systems because the nanodimensions are able to overcome natural barriers, resulting in potential biological damage.
The main aim of this Ph.D. Thesis was the evaluation of the potential toxic effects of several NMs on aquatic organisms used as models considering their increasing use in the product market. Short and long-term ecotoxicological assays developed, searching for specific biomarkers of exposure by immunohistochemistry, western blotting and gene expression analysis.
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Xie, Fangyou. "Pressure Driven Desalination Utilizing Nanomaterials." DigitalCommons@CalPoly, 2020. https://digitalcommons.calpoly.edu/theses/2204.
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Nanomaterials such as graphene oxide and carbon nanotubes, have demonstrated excellent properties for membrane desalination, including decrease of maintenance, increase of flux rate, simple solution casting, and impressive chemical inertness. Here, two projects are studied to investigate nanocarbon based membrane desalination. The first project is to prepare hybrid membranes with amyloid fibrils intercalated with graphene oxide sheets. The addition of protein amyloid fibrils expands the interlayer spacing between graphene oxide nanosheets and introduces additional functional groups in the diffusion pathways, resulting in increase of flux rate and rejection rate for the organic dyes. Amyloid fibrils also provide structural assistance to the hybrid membrane, which supresses cracking and instability of graphene oxide sheets. The second project is to fabricate polymer nanocomposite membranes with carbon nanotubes encapsulated by polymerized surfactants. The designed polymerizable surfactant forms lyotropic liquid crystalline mesophases in an aqueous medium with hexagonal packing of cylindrical micelles. The adsorption of surfactants on the surface of carbon nanotubes allows a stable dispersion of carbon nanotubes encapsulated in the cylindrical micelles, resulting in the ordered structure. After photo-polymerization, the composite membranes display enhanced dye rejection. Both projects have shown promising ways to improve membrane filtration by using nanomaterials.
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Yum, Kyungsuk. "Interfacing nanomaterials with fluids and living biological systems /." 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3363123.
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Thesis (Ph. D.)--University of Illinois at Urbana-Champaign, 2009.Source: Dissertation Abstracts International, Volume: 70-06, Section: B, page: 3757. Adviser: Min-Feng Yu. Includes bibliographical references (leaves 93-110). Available on microfilm from Pro Quest Information and Learning.
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"Synthesis, Characterization And Functionalization Of Silicon Nanoparticle Based Hybrid Nanomaterials For Photovoltaic And Biological Applications." Tulane University, 2014.
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Silicon nanoparticles are attractive candidates for biological, photovoltaic and energy storage applications due to their size dependent optoelectronic properties. These include tunable light emission, high brightness, and stability against photo-bleaching relative to organic dyes (see Chapter 1). The preparation and characterization of silicon nanoparticle based hybrid nanomaterials and their relevance to photovoltaic and biological applications are described. The surface-passivated silicon nanoparticles were produced in one step from the reactive high-energy ball milling (RHEBM) of silicon wafers with various organic ligands. The surface structure and optical properties of the passivated silicon nanoparticles were systematically characterized. Fast approaches for purifying and at the same time size separating the silicon nanoparticles using a gravity GPC column were developed. The hydrodynamic diameter and size distribution of these size-separated silicon nanoparticles were determined using GPC and Diffusion Ordered NMR Spectroscopy (DOSY) as fast, reliable alternative approaches to TEM. Water soluble silicon nanoparticles were synthesized by grafting PEG polymers onto functionalized silicon nanoparticles with distal alkyne or azide moieties. The surface-functionalized silicon nanoparticles were produced from the reactive high-energy ball milling (RHEBM) of silicon wafers with a mixture of either 5-chloro-1-pentyne in 1-pentyne or 1,7 octadiyne in 1-hexyne to afford air and water stable chloroalkyl or alkynyl terminated nanoparticles, respectively. Nanoparticles with the ω-chloroalkyl substituents were easily converted to ω-azidoalkyl groups through the reaction of the silicon nanoparticles with sodium azide in DMF. The azido terminated nanoparticles were then grafted with monoalkynyl-PEG polymers using a copper catalyzed alkyne-azide cycloaddition (CuAAC) reaction to afford core-shell silicon nanoparticles with a covalently attached PEG shell. Covalently linked silicon nanoparticle clusters were synthesized via the CuAAC “click” reaction of functional silicon nanoparticles with α,ω-functional PEG polymers of various lengths. Dynamic light scattering studies show that the flexible globular nanoparticle arrays undergo a solvent dependent change in volume (ethanol> dichloromethane> toluene) similar in behavior to hydrogel nanocomposites. A novel light-harvesting complex and artificial photosynthetic material based on silicon nanoparticles was designed and synthesized. Silicon nanoparticles were used as nanoscaffolds for organizing the porphyrins to form light-harvesting complexes thereby enhancing the light absorption of the system. The energy transfer from silicon nanoparticles to porphyrin acceptors was investigated by both steady-state and time-resolved fluorescence spectroscopy. The energy transfer efficiency depended on the donor-acceptor ratio and the distance between the nanoparticle and the porphyrin ring. The addition of C60 resulted in the formation of silicon nanoparticle-porphyrin-fullerene nanoclusters which led to charge separation upon irradiation of the porphyrin ring. The electron-transfer process between the porphyrin and fullerene was investigated by femto-second transient absorption spectroscopy. Finally, the water soluble silicon nanoparticles were used as nanocarriers in photodynamic therapeutic application, in which can selectively deliver porphyrins into human embryonic kidney 293T (HEK293T) cells. In particular, the PEGylated alkynyl-porphyrins were conjugated onto the azido-terminated silicon nanoparticles via a CuAAC “click” reaction. The resultant PEGylated porphyrin grafted silicon nanoparticles have diameters around 13.5 ± 3.8 nm. The cryo-TEM and conventional TEM analysis proved that the PEGylated porphyrin grafted silicon nanoparticle could form the micelle-like structures at higher concentration in water via self-assembly. The UV-Vis absorption analysis demonstrated that the silicon nanoparticle could reduce the porphyrin aggregation in water which can reduce the photophysical activity of porphyrin. In addition, the nanoparticle complex was capable of producing singlet oxygen when the porphyrin units were excited by light. The cell studies demonstrated that the silicon nanoparticle could deliver the porphyrin drugs into HEK293T cells and accumulate in the mitochondria where the porphyrin could serve as an efficient photosensitizer to kill the cells via mitochondrial apoptotic pathway.acase@tulane.edu
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Dimou, Kaotar. "Analyse systématique des données sur le control banding et proposition d’une méthode semi-quantitative selon des critères physico-chimiques et biologiques des nanomatériaux manufacturés." Thèse, 2019. http://hdl.handle.net/1866/23581.
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Parmi les méthodologies d’appréciation du danger ayant connu une forte croissance ces dernières décennies figurent le Control Banding (CB). Selon une estimée du NIOSH (National Institute for Occupational Safety and Health), cette approche qualitative a été développé dans l’industrie pharmaceutique dans un but concret de protéger près de 90% de travailleurs n’ayant pas accès à des services de santé, de sécurité et d’hygiène au travail. Actuellement, cette approche peut être adaptée aux spécificités des nanomatériaux (NMs) pour lesquelles peu de connaissances scientifiques sont disponibles sur les risques potentiels pour la santé et pour la sécurité des travailleurs. Au cours des dernières années, différentes études ont porté sur l’application de l’approche CB et plusieurs pays ont développé leur propre méthode adaptée aux NMs. Par contre, tous les modèles développés sont basés sur des critères qualitatifs du danger et de l’exposition. Une approche semi-quantitative permettrait de mieux gérer les dangers liés à la manipulation des NMs. L’objectif de ce mémoire était de développer une approche semi-quantitative d’évaluation des dangers sur la base d’une approche de CB. Pour ce faire, une analyse systématique de la littérature scientifique des 20 dernières années sur l’approche de CB a été effectué. Les bases de données Toxline, Pubmed et Google Scholar ont été consultées, couvrant la période de janvier 1996 à novembre 2016, en utilisant 4 mots-clés: control banding, nanomaterials, physicochemical, biological characteristics. Cette recherche a permis d’identifier 982 articles, dont 11% (91) furent retenus en première intention pour au final en garder 6 % (51/982). Il ressort de cette revue que le CB est une approche complémentaire aux méthodes d’évaluation quantitative et que les outils CB développés pour les NMs sont tous de nature qualitative, en réponse à une exposition. Une approche semi-quantitative où il y a maillage entre la caractérisation biologique avec les tests in vitro et la caractérisation physicochimique par des analyses chimiques pour mieux caractériser le niveau de dangérosité des NMs tel que présenté dans le présent mémoire permettrait une utilisation plus judicieuse du CB. Cette approche novatrice du CB dépasse largement l’utilisation que l’on en fait actuellement en hygiène du travail, devrait accroître la confiance dans le jugement des experts en santé au travail, afin d’orienter les travailleurs et la population générale vers une utilisation sécuritaire des NMs.Among the hazards assessment methodology that has grown exponentially during the last decade, mention Control Banding (CB). According to the National Institute for Occupational Safety and Health (NIOSH), this qualitative approach originally developed in the pharmaceutical industry, aims to protect approximately 90% or 2.7 billion workers that do not have access to occupational safety, health, and hygiene. Currently, this approach can be adapted to the specificities of nanomaterials (NMs), considering the significant lack of scientific knowledge about their potential health and safety risks to workers. In recent years, several CB models have been developed, and many countries have created their own nano-specific CB instruments. However, a semi-quantitative approach would better managing the hazards of handling nanomaterials in the workplace. This thesis aimed to perform a systematic literature review over the past 20 years about the CB approach and then to suggest a semi-quantitative hazard assessment. The official Web pages of the databases Toxline, Pubmed and Google Scholar were used, covering the literature from January 1996 to November 2016, with use of the 4 keywords to locate relevant articles: Control Banding, nanomaterials, physico-chemical, biological characteristics. These searches yielded a total of 982 articles, 11% (91) were retained to eventually retain 6% (51/982). This review shows that the CB approach is an interesting and complementary methodology to quantitative evaluation methods and the CB tools developed for NMs are all qualitative in nature, in response to an exposure and adapted to different work environments. It is possible to make better use by proposing a semi-quantitative approach based on physicochemical and toxicity parameters of NMs to better characterize their degree of dangerousness. We propose here an original methodology proposing the interaction of in vitro tests and chemical analyzes. This innovative Control Banding approach should increase confidence in the judgment of experts and industry, as well as to guide both exposed workers and the uses of NMs in this industry.
Books on the topic "Biological Science - Nanomaterials"
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Thomas, Sabu, Nandakumar Kalarikkal, and Obey Koshy. Nanomaterials: Physical, Chemical, and Biological Applications. Apple Academic Press, Incorporated, 2018.
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Nanomaterials: Physical, Chemical, and Biological Applications. Taylor & Francis Group, 2018.
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Thomas, Sabu, Nandakumar Kalarikkal, and Obey Koshy. Nanomaterials: Physical, Chemical, and Biological Applications. Apple Academic Press, Incorporated, 2018.
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Carter, Joshua D., Chenxiang Lin, Yan Liu, Hao Yan, and Thomas H. LaBean. DNA-based self-assembly of nanostructures. Edited by A. V. Narlikar and Y. Y. Fu. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533053.013.24.
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This article examines the DNA-based self-assembly of nanostructures. It first reviews the development of DNA self-assembly and DNA-directed assembly, focusing on the main strategies and building blocks available in the modern molecular construction toolbox, including the design, construction, and analysis of nanostructures composed entirely of synthetic DNA, as well as origami nanostructures formed from a mixture of synthetic and biological DNA. In particular, it considers the stepwise covalent synthesis of DNA nanomaterials, unmediated assembly of DNA nanomaterials, hierarchical assembly, nucleated assembly, and algorithmic assembly. It then discusses DNA-directed assembly of heteromaterials such as proteins and peptides, gold nanoparticles, and multicomponent nanostructures. It also describes the use of complementary DNA cohesion as 'smart glue' for bringing together covalently linked functional groups, biomolecules, and nanomaterials. Finally, it evaluates the potential future of DNA-based self-assembly for nanoscale manufacturing for applications in medicine, electronics, photonics, and materials science.
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Challa S. S. R. Kumar. Biological and Pharmaceutical Nanomaterials (Nanotechnologies for the Life Sciences). Wiley-VCH, 2006.
Find full textBook chapters on the topic "Biological Science - Nanomaterials"
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Pandit, Jayamanti, Md Sabir Alam, Jamilur R. Ansari, Monisha Singhal, Nidhi Gupta, Aafrin Waziri, Kajal Sharma, and Fahim Hyder Potto. "Multifaced Applications of Nanoparticles in Biological Science." In Nanomaterials in the Battle Against Pathogens and Disease Vectors, 17–50. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003126256-2.
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Omran, Basma A. "Inspired Biological Synthesis of Nanomaterials Using Eukaryotic Microbial Nano-Machinery." In Nanobiotechnology: A Multidisciplinary Field of Science, 81–109. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-46071-6_3.
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Sakthinarendran, S., M. Ravi, and G. Mirunalini. "Nano-Bioremediation Using Biologically Synthesized Intelligent Nanomaterials." In Nanotechnology in the Life Sciences, 541–52. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-80371-1_18.
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Pathakoti, Kavitha, Lavanya Goodla, Manjunath Manubolu, and Huey-Min Hwang. "Nanoparticles and Their Potential Applications in Agriculture, Biological Therapies, Food, Biomedical, and Pharmaceutical Industry: A Review." In Nanotechnology and Nanomaterial Applications in Food, Health, and Biomedical Sciences, 121–62. Series statement: Innovations in agricultural and biological engineering: Apple Academic Press, 2019. http://dx.doi.org/10.1201/9780429425660-3.
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Wani, Irshad Ahmad, and Tokeer Ahmad. "Understanding Toxicity of Nanomaterials in Biological Systems." In Materials Science and Engineering, 1533–57. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1798-6.ch062.
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Nanotechnology is a growing applied science having considerable global socioeconomic value. Nanoscale materials are casting their impact on almost all industries and all areas of society. A wide range of engineered nanoscale products has emerged with widespread applications in fields such as energy, medicine, electronics, plastics, energy and aerospace etc. While the market for nanotechnology products will have grown over one trillion US dollars by 2015, the presence of these material is likely to increase leading to increasing likelihood of exposure. The direct use of nanomaterials in humans for medical and cosmetic purposes dictates vigorous safety assessment of toxicity. Therefore this book chapter provides the detailed toxicity assessment of various types of nanomaterials.
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Wani, Irshad Ahmad, and Tokeer Ahmad. "Understanding Toxicity of Nanomaterials in Biological Systems." In Pharmaceutical Sciences, 1492–516. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1762-7.ch057.
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Nanotechnology is a growing applied science having considerable global socioeconomic value. Nanoscale materials are casting their impact on almost all industries and all areas of society. A wide range of engineered nanoscale products has emerged with widespread applications in fields such as energy, medicine, electronics, plastics, energy and aerospace etc. While the market for nanotechnology products will have grown over one trillion US dollars by 2015, the presence of these material is likely to increase leading to increasing likelihood of exposure. The direct use of nanomaterials in humans for medical and cosmetic purposes dictates vigorous safety assessment of toxicity. Therefore this book chapter provides the detailed toxicity assessment of various types of nanomaterials.
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Tabassum, Heena, Allika Sailaja, Huda Afreen, and Minal Wani. "Sewage Treatment Using Nanoparticles." In Sustainable Development. IntechOpen, 2023. http://dx.doi.org/10.5772/intechopen.109407.
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This chapter provides a brief overview of nanomaterials, including classification, shape and structure, nanomaterial types, and applications in the degradation of recalcitrant organic contaminants. With the rapid advancement of nanotechnology science, the use of nanomaterials in environmental applications, particularly water treatment, has piqued the scientific community’s interest in recent decades. Nanomaterials have unique properties such as surface-to-volume ratio, quantum effect, low band-gap energy, and so on, which enhance catalytic performance. Wastewater treatment is a critical task of the twenty-first century since it protects the health of our environment and living beings. Because of its ability to affect both living and nonliving organisms, wastewater is always viewed as a serious source of environmental contamination. Many physical, biological, and chemical modes of treatment are implied to comply with wastewater discharge standards set by competent national agencies for environmental protection.
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Rather, Gulzar Ahmed, Arghya Chakravorty, Basharat Ahmad Bhat, Ishfaq Majeed Malik, Fayaz Hussain Mir, Siva Sankar Sana, Vimala Raghavan, Anima Nanda, and Moharana Choudhury. "Routes of Synthesis and Characterizations of Nanoparticles." In Applications of Nanomaterials in Agriculture, Food Science, and Medicine, 288–309. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-5563-7.ch016.
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An interesting aspect of nanotechnology is the remarkable size-dependent physico-chemical properties of nanomaterials that have led to the rise of synthesis procedures for nanomaterials across a range of sizes, shapes, and chemical compositions. This chapter will concentrate on the different methods such as electron irradiation, laser ablation, and chemical reduction, biological methods, photochemical methods; microwave processing, chemical vapour condensation (CVC), arc discharge, hydrogen plasma-metal reaction, and laser pyrolysis in the vapour phase. This chapter will also include the various characterization techniques for the conformation of nanomaterials such as UV-visible spectroscopy, x-ray diffraction, and electron microscopy (e.g., transmission electron microscopy [TEM], scanning electron microscopy [SEM], and atomic force microscopy [AFM]).
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Malik, Sumira. "Implication of Nanoparticles in Drosophila Toxicology Research." In Applications of Nanomaterials in Agriculture, Food Science, and Medicine, 330–40. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-5563-7.ch018.
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Homo sapiens and Drosophila malenogaster, a fruit fly, share genetic homology in development process regulated through fundamental biological pathways and conserved mechanisms conserved as a process of evolution among these species. Drosophila melanogaster is an eminent model organism to study diverse biological species. In this chapter, the use of wide variety of nano particles and their impact on Drosophila melanogastsr's development, longevity, characteristics of reproduction has been studied.
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Nogueira, Verónica Inês Jesus Oliveira, Ana Gavina, Sirine Bouguerra, Tatiana Andreani, Isabel Lopes, Teresa Rocha-Santos, and Ruth Pereira. "Ecotoxicity and Toxicity of Nanomaterials with Potential for Wastewater Treatment Applications." In Materials Science and Engineering, 1182–216. IGI Global, 2017. http://dx.doi.org/10.4018/978-1-5225-1798-6.ch046.
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Nanotechnology holds the promise of develop new processes for wastewater treatment. However, it is important to understand what the possible impacts on the environment of NMs. This study joins all the information available about the toxicity and ecotoxicity of NMs to human cell lines and to terrestrial and aquatic biota. Terrestrial species seems more protected, since effects are being recorded for concentrations higher than those that could be expected in the environment. The soil matrix is apparently trapping and filtering NMs. Further studies should focus more on indirect effects in biological communities rather than only on effects at the individual level. Aquatic biota, mainly from freshwater ecosystems, seemed to be at higher risk, since dose effect concentrations recorded were remarkable lower, at least for some NMs. The toxic effects recorded on different culture lines, also give rise to serious concerns regarding the potential effects on human health. However, few data exists about environmental concentrations to support the calculation of risks to ecosystems and humans.
Conference papers on the topic "Biological Science - Nanomaterials"
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Li, Yiqun. "Near-infrared brain imaging based on nanomaterials." In International Conference on Biological Engineering and Medical Science (ICBIOMed2022), edited by Gary Royle and Steven M. Lipkin. SPIE, 2023. http://dx.doi.org/10.1117/12.2669410.
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Malek, Nik Ahmad Nizam Nik, and Nor Suriani Sani. "Challenges in bionanotechnology innovation: Issues in commercialization of nanomaterials for biological and medical application." In THE 4TH INTERNATIONAL CONFERENCE ON LIFE SCIENCE AND TECHNOLOGY (ICoLiST). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0111210.
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Rasulev, Bakhtiyor. "APPLICATION OF COMBINED DATA-DRIVEN COMPUTATIONAL CHEMISTRY AND CHEMINFORMATICS APPROACHES TO PREDICT PROPERTIES OF MATERIALS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.002r.
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For the last two decades, breakthrough research has been going on in all aspects of materials science at accelerated pace. New materials of unprecedented functionality and performance are being developed and characterized. Moreover, the new materials with improved functionality are in high demand in the marketplace and this need increases in an exponential way for the new materials of desired functionality and performance. Here we show the application of combined computational and cheminformatics methods in various materials properties prediction, including organometallic materials, polymeric materials and nanomaterials. Since most of the materials are complex entities from a chemical point of view, the investigation of them requires an interdisciplinary approach, involving multiple aspects ranging from physics and chemistry to biology and informatics. In this report we show how the combination of computational chemistry, available experimental data, machine learning and cheminformatics approaches can help in materials research and properties assessment, such as physico-chemical properties, toxicity, and biological activity. We discuss here a few case studies where data-driven models developed to reveal the relationships between the physicochemical properties, biological activity and structural characteristics, by application quantum chemical, protein-ligand docking, cheminformatics approaches and developed nanodescriptors.
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Santos, Jailson de Araújo. "NANOMATERIAIS COM APLICAÇÕES BIOLÓGICAS: UMA REVISÃO DE LITERATURA." In II Congresso Brasileiro de Ciências Biológicas On-line. Revista Multidisciplinar de Educação e Meio Ambiente, 2021. http://dx.doi.org/10.51189/rema/1304.
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Introdução: Os nanomateriais estão na vanguarda do campo de rápido desenvolvimento da nanotecnologia. Suas propriedades únicas, que dependem do tamanho das partículas sintetizadas, tornam esses materiais superiores e indispensáveis em muitas áreas da atividade humana, incluindo as ciências biológicas. Objetivo: Dessa forma, o presente estudo busca apresentar, através de uma revisão de literatura, os mais recentes desenvolvimentos no campo dos nanomateriais aplicados a biologia. Material e métodos: A revisão de literatura consistiu na busca por artigos científicos e livros publicados nas bases de dados Scielo, Scopus e Web of Science. Na busca dos artigos e livros foram utilizados os descritores: “nanomateriais”, “biologia”, “biopolímeros” e “biomateriais” os quais foram utilizados isolados e/ou em combinações. Foram encontrados diversos artigos e livros relacionados ao tema e os mesmos foram analisados quanto a relevância do tema voltado para aplicação na área de ciências biológicas. Resultados: Os resultados apontaram muitos exemplos do uso de biomateriais nanométricos em diversas áreas da biologia. Observou-se que na genética, diversos nanomateriais são utilizados com os mais variados propósitos. Como por exemplo, a utilização de nanomateriais na terapia gênica para a entrega de genes e drogas em células específicas. Além desse, observou-se o uso da nanotecnologia para a sondagem da estrutura do DNA e o uso como marcadores biológicos fluorescentes. Além disso, observou-se aplicações de nanomateriais no campo da biologia celular, tais como na separação e purificação de moléculas e células biológicas, biossensores celulares, e utilização em microssistemas enzimáticos. Na área da microbiologia, verificou-se a utilização de biomateriais com atividade antibacteriana, antifúngica e na detecção biológica de patógenos. Conclusão: Portanto, a partir dos resultados apresentados nesse estudo, verifica-se que o uso de nanomateriais nas diferentes áreas da biologia vem crescendo cada vez mais e se torna de extrema importância para o cenário da pesquisa atual tendo em vista que essa tecnologia permite diferentes aplicações com excelentes resultados.
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Zhu, Xinyi. "Applications of self-aggregating peptide as a novel bio-nanomaterial." In International Conference on Biological Engineering and Medical Science (ICBIOMed2022), edited by Gary Royle and Steven M. Lipkin. SPIE, 2023. http://dx.doi.org/10.1117/12.2669015.
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Okamoto, Hiromi, Shun Hashiyada, Yoshio Nishiyama, and Tetsuya Narushima. "Imaging Chiral Plasmons." In JSAP-OSA Joint Symposia. Washington, D.C.: Optica Publishing Group, 2017. http://dx.doi.org/10.1364/jsap.2017.5a_a410_1.
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Chirality is a broad concept that characterizes structures of systems in almost all hierarchy of materials in natural sciences. Molecular chirality is sometimes essential in biological functions. Also in nanomaterials sciences, chirality plays a key role. It is of fundamental importance to investigate internal structures (geometrical distributions) of chiral optical responses in nanomaterials, to design chiral features of the materials and their functions. We developed near-field optical activity (typically circular dichroism, CD) imaging systems that allow us to visualize local structures of optical activity in nanomaterials, and observed near-field CD images of two-dimensional gold nanostructures fabricated with electron beam lithography lift-off technique. We found that the amplitudes of local CD signals were as large as 100 times the macroscopic CD signals of the same samples, for two-dimensional chiral gold nanostructures [1]. Even highly symmetric achiral structures that never give CD signals macroscopically gave locally very strong CD signals (a typical example for a rectangular nanostructure is shown in Figure 1) [2,3]. In this case, average of the signal over the nanostructure yielded roughly null CD intensity. While achiral nanostructures show in general local CD activities as mentioned above, circularly symmetric (two-dimensionally isotropic) nanostructures, such as circular disks, never give CD signals at any local positions. However, when the circular disk is illuminated with linearly polarized light, the circular symmetry is broken, and thus the system potentially yields locally chiral optical (i.e., circularly polarized) fields. To demonstrate that, we extended the near-field CD microscope, and enabled irradiation of well- defined linearly polarized near-field on the sample and detection of scattered-field ellipticity and polarization azimuth angle. We found for circular gold disks that the scattered field was actually elliptically polarized. The ellipticity and the azimuth angle of the scattered field depended on the incident polarization angle and relative position on the disk.