Academic literature on the topic 'Biological and Medical Chemistry'
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Journal articles on the topic "Biological and Medical Chemistry"
Stechenko, Olena. "BIOLOGICAL AND BIOORGANIC CHEMISTRY IN THE MEDICAL CURRICULA." Science and Education 2019, no. 2 (February 2019): 5–12. http://dx.doi.org/10.24195/2414-4665-2019-2-1.
Full textKornberg, Arthur. "Chemistry — the lingua franca of the medical and biological sciences." Chemistry & Biology 3, no. 1 (January 1996): 3–5. http://dx.doi.org/10.1016/s1074-5521(96)90075-7.
Full textLesyk, Roman. "Drug design: 4-thiazolidinones applications. Part 1. Synthetic routes to the drug-like molecules." Journal of Medical Science 89, no. 1 (March 31, 2020): e406. http://dx.doi.org/10.20883/medical.406.
Full textHogg, Neil. "Biological chemistry and clinical potential of S-nitrosothiols." Free Radical Biology and Medicine 28, no. 10 (May 2000): 1478–86. http://dx.doi.org/10.1016/s0891-5849(00)00248-3.
Full textKoppenol, W. H. "Superoxide ion: Chemistry and biological implications, volume I." Free Radical Biology and Medicine 9, no. 6 (January 1990): 541. http://dx.doi.org/10.1016/0891-5849(90)90132-3.
Full textKoppenol, W. H. "Superoxide ion: Chemistry and biological implications, volume II." Free Radical Biology and Medicine 12, no. 5 (January 1992): 449. http://dx.doi.org/10.1016/0891-5849(92)90094-w.
Full textKawase, Masami, Setsuo Saito, and Noboru Motohashi. "Chemistry and biological activity of new 3-benzazepines." International Journal of Antimicrobial Agents 14, no. 3 (April 2000): 193–201. http://dx.doi.org/10.1016/s0924-8579(99)00155-7.
Full textLiang, Pi-Hui, Chung-Yi Wu, William A. Greenberg, and Chi-Huey Wong. "Glycan arrays: biological and medical applications." Current Opinion in Chemical Biology 12, no. 1 (February 2008): 86–92. http://dx.doi.org/10.1016/j.cbpa.2008.01.031.
Full textAli, Fayaz, Narayan S Hosmane, and Yinghuai Zhu. "Boron Chemistry for Medical Applications." Molecules 25, no. 4 (February 13, 2020): 828. http://dx.doi.org/10.3390/molecules25040828.
Full textAmirov, N. K., and Т. A. Abdullin. "70th anniversary of the Department of Inorganic Chemistry of Kazan State Medical University." Kazan medical journal 80, no. 2 (March 25, 1999): 158–59. http://dx.doi.org/10.17816/kazmj66496.
Full textDissertations / Theses on the topic "Biological and Medical Chemistry"
Nichols, Alexander J. "Optical Molecular Sensing in Complex Biological Environments." Thesis, Harvard University, 2014. http://nrs.harvard.edu/urn-3:HUL.InstRepos:14226087.
Full textPokhrel, Laxman. "Design, synthesis, and biological evaluation of tricyclic pyrones and thiouridine nucleosides." Diss., Kansas State University, 2013. http://hdl.handle.net/2097/16233.
Full textDepartment of Chemistry
Duy H. Hua
The first chapter in this thesis includes the design, synthesis, and evaluation of anti-Alzheimer and anti-norovirus activities of tricyclic pyrones (TPs). Alzheimer’s disease is a major cause of dementia and sixth leading cause of death; it is a growing problem all over the world. On the other hand, norovirus, a highly contagious agent is responsible for more than 90% of non-bacterial gastroenteritis causing severity mainly in the closed environments. No drugs exist to eradicate the symptoms developed by both of these disorders. Studies have shown that the development of Alzheimer’s disease and the infection of norovirus are dependent on cholesterol metabolism. More specifically, the inhibition of acyl-CoA: cholesterol acyltrasferase (ACAT) led to the reduction of plaques in Alzheimer’s disease as well as reduced the infection of norovirus. Mimicking the structure of CP2, a TP with promising anti-Alzheimer activities, a library of tricyclic pyrones containing phenyl, naphthyl, heterocyclic, and dipeptidyl moieties were synthesized and evaluated for their anti-Alzheimer and anti-norovirus efficacies. Several TPs containing phenyl and naphthyl groups showed sub-micromolar to nanomolar potencies for the protection of neuronal MC65 cells from Aβ-oligomers induced death. Similarly, the TPs containing pyrrolyl, imidazolyl, and quinolinyl moieties were effective to inhibit the norovirus replication in low micromolar range. The most effective TPs from MC65 cells protection assay were also effective in the inhibition ACAT and up-regulation ABCA1 gene. The second chapter in this thesis includes the design, synthesis, and anti-norovirus activity of thiouridine nucleosides. Many nucleosides have demonstrated effective inhibition of viral RNA polymerase, and some are progressing at different level of clinical trials for the treatment of hepatitis C virus. Some of the nucleosides, including 2’-C-methyl and 2’-amino substituted analogs, were found to effectively inhibit the norovirus replication. In the search of more potent anti-noroviral compounds, two thiouridine nucleosides were synthesized and evaluated as anti-norovirus agents. Both of these analogs were ineffective up to 50 μM for the inhibition of norovirus replication in cell based assay. Proposed work of converting these nucleosides to their phosphoramidate derivatives is also described.
Njaria, Paul Magutu. "Antimycobacterial 2-aminoquinazolinones and benzoxazole-based oximes: synthesis, biological evaluation, physicochemical profiling and supramolecular derivatization." Doctoral thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/26954.
Full textForsyth, Andrea N. "Synthesis and Biological Evaluation of Rigid Analogues of Methamphetamines." ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1436.
Full textZhu, Chongyu. "Polymeric drug delivery systems for biological antimicrobial agents." Thesis, University of Warwick, 2017. http://wrap.warwick.ac.uk/91996/.
Full textShi, Fengjian. "LASER ELECTROSPRAY MASS SPECTROMETRY: INSTRUMENTATION AND APPLICATION FOR DIRECT ANALYSIS AND MOLECULAR IMAGING OF BIOLOGICAL TISSUE." Diss., Temple University Libraries, 2017. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/445496.
Full textPh.D.
This dissertation elucidates the instrumentation and application of a hybrid ambient ionization source, laser electrospray mass spectrometry (LEMS), for the direct analysis and molecular imaging of biological tissue without matrix deposition. In LEMS, laser pulses from a Ti:Sapphire laser amplifier (60 fs, 800 nm, and 1 mJ) interact with surface analytes and transfer them from the condensed phase into the gas phase without the requirement of either exogenous matrix or endogenous water in the sample. The laser vaporized analytes are captured and ionized by an electrospray source, and finally detected by a mass analyzer. It was found that a turn-key, robust femtosecond fiber laser with longer wavelength, longer duration, and lower pulse energy at 1042 nm, 425 fs, and 50 µJ, respectively, provided comparable results with the Ti:Sapphire laser. Vaporization of intact, dried or aqueous cytochrome c and lysozyme samples was demonstrated by the fiber laser. A charge states distribution at lower charge states indicating folded conformation of proteins and the hemoglobin α subunit-heme complex from whole blood was observed. Endogenous anthocyanins, sugars, and other metabolites were detected and revealed the anticipated metabolite profile for the flower petal and leaf samples by the fiber laser. Phospholipids, especially phosphatidylcholine, were identified from a fresh mouse brain section sample. These lipid features were suppressed in both the fiber laser and Ti:Sapphire LEMS measurement in the presence of optimal cutting temperature compounds which are commonly used in animal tissue cryosectioning. This dissertation also details the design of an automated mass spectrometry imaging source based on the Ti:Sapphire LEMS. The laser, translation stage, and mass analyzer are synchronized and controlled using a customized user interface to enable step-by-step scanning of the area of interest on a given tissue sample. The imaging source is coupled with a high resolution accurate mass quadrupole time-of-flight (QTOF) mass analyzer with tandem mass analysis capability. A lateral resolution of 60 µm was demonstrated on a patterned ink film by LEMS imaging. Plant metabolites including sugar and anthocyanins were directly imaged from a leaf sample. Small metabolites, lipids and proteins were simultaneously imaged from a single tissue section of a pig liver sample. Biomarkers of blood-brain barrier damage and traumatic brain injury (TBI) that occurred during the injury were detected and imaged from a TBI mouse brain. The loading values from principal component analysis (PCA) were shown to be useful for identification of features of interest from the large LEMS imaging dataset.
Temple University--Theses
Jaramillo, Forcada Tatiana. "Synthesis and biological evaluation of natural and synthetic ganoderic acids." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/43313/.
Full textPetersson, Nina. "Optimisation of capillary gel electrophoresis method for enhanced separation of mRNA shortmers." Thesis, Uppsala universitet, Institutionen för kemi - BMC, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-351119.
Full textVerma, Abha. "Design, Synthesis and Biological Evaluation of Novel Cannabinoid Antagonist." ScholarWorks@UNO, 2012. http://scholarworks.uno.edu/td/1527.
Full textMuth, Aaron. "Design, Synthesis, and Biological Evaluation of Novel Polyamine Transport System Probes and their Application to Human Cancers." Doctoral diss., University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5348.
Full textPh.D.
Doctorate
Chemistry
Sciences
Chemistry
Books on the topic "Biological and Medical Chemistry"
Raymond, Kenneth William. General, organic, and biological chemistry: An integrated approach. 2nd ed. Hoboken, NJ: Wiley, 2008.
Find full textRaymond, Kenneth William. General, organic, and biological chemistry: An integrated approach. 3rd ed. Hoboken, N.J: Wiley, 2010.
Find full textGeneral, organic, and biological chemistry: An integrated approach. Hoboken, NJ: J. Wiley, 2006.
Find full textHostettmann, K. Handbook of chemical and biological plant analytical methods. Chichester, West Sussex: John Wiley & Sons Inc., 2014.
Find full textS, Subramanian K., and Woittiez J. R. W, eds. Element analysis of biological samples: Principles and practice. Boca Raton: CRC Press, 1998.
Find full textD, Loike J., ed. Lignans: Chemical, biological, and clinical properties. Cambridge [England]: Cambridge University Press, 1990.
Find full textGarshin, Anatoliy. General and inorganic chemistry in diagrams, figures, tables, and chemical reactions. ru: INFRA-M Academic Publishing LLC., 2020. http://dx.doi.org/10.12737/1070937.
Full textZhou, Michael. Regulated bioanalytical laboratories: Technical and regulatory aspects from global perspectives. Hoboken, N.J: Wiley, 2011.
Find full textCéspedes, Carlos L. Natural antioxidants and biocides from wild medicinal plants. Cambridge, MA: CAB International, 2013.
Find full text1944-, Hostettmann K., Gupta Mahabir P, Marston A. 1953-, International Organization for Chemical Sciences in Development., and CYTED (Organization), eds. Chemistry, biological, and pharmacological properties of medicinal plants from the Americas: Proceedings of the IOCD/CYTED Symposium, Panama City, Panama, 23-26 February 1997. Amsterdam, The Netherlands: Harwood Academic Publishers, 1999.
Find full textBook chapters on the topic "Biological and Medical Chemistry"
Gorbik, P. P., L. P. Storozhuk, A. A. Chuiko†, L. Yu. Vergun, and V. F. Chekhun. "Magnetically sensitive nanocomposites for medical and biological applications." In Surface Chemistry in Biomedical and Environmental Science, 299–306. Dordrecht: Springer Netherlands, 2006. http://dx.doi.org/10.1007/1-4020-4741-x_26.
Full textBoitrel, Bernard. "Bismuth Complexes of Porphyrins and their Potential in Medical Applications." In Biological Chemistry of Arsenic, Antimony and Bismuth, 209–40. Chichester, UK: John Wiley & Sons, Ltd, 2010. http://dx.doi.org/10.1002/9780470975503.ch9.
Full textVitali, Francesca, and Rudi Fasan. "Biological and Hybrid Biological/Chemical Strategies in Diversity Generation of Peptidic Macrocycles." In Practical Medicinal Chemistry with Macrocycles, 155–84. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119092599.ch7.
Full textRoda, A., S. Girotti, G. Carrea, P. Simoni, M. A. Angellotti, and R. Rizzoli. "Immobilized Biospecific Proteins in Analytical Clinical Chemistry." In Analytical Uses of Immobilized Biological Compounds for Detection, Medical and Industrial Uses, 249–65. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-2895-4_21.
Full textBrothers, Penelope J., and Christy E. Ruggiero. "Coordination and Solution Chemistry of the Metals: Biological, Medical and Environmental Relevance." In The Group 13 Metals Aluminium, Gallium, Indium and Thallium: Chemical Patterns and Peculiarities, 519–611. Chichester, UK: John Wiley & Sons, Ltd, 2011. http://dx.doi.org/10.1002/9780470976548.ch9.
Full textMishra, Bibhudatta, and Gunjan Joshi. "Serotonin: Chemical, Biological, and Therapeutic Aspects." In Handbook of Research on Medicinal Chemistry, 201–37. Toronto ; New Jersey : Apple Academic Press, 2017.: Apple Academic Press, 2017. http://dx.doi.org/10.1201/9781315207414-6.
Full textTrisciuoglio, Daniela, and Dante Rotili. "Histone Acetyltransferase Enzymes: From Biological Implications to Most Relevant Inhibitors." In Topics in Medicinal Chemistry, 93–122. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/7355_2019_71.
Full textWang, Jianing, Ravindra K. Rawal, and Chung K. Chu. "Recent Advances in Carbocyclic Nucleosides: Synthesis and Biological Activity." In Medicinal Chemistry of Nucleic Acids, 1–100. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118092804.ch1.
Full textHe, Shuqing, and Zhen Cheng. "Advancements of Second Near-Infrared Biological Window Fluorophores: Mechanism, Synthesis, and Application In Vivo." In Topics in Medicinal Chemistry, 81–123. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/7355_2019_89.
Full textCarta, Fabrizio, Andrea Angeli, Christian D. T. Nielsen, Claudiu T. Supuran, and Agostino Cilibrizzi. "New Biological Targets for the Treatment of Leishmaniasis." In Medicinal Chemistry of Neglected and Tropical Diseases, 281–309. Boca Raton, FL : CRC Press, Taylor & Francis Group, [2018]: CRC Press, 2019. http://dx.doi.org/10.1201/9781351011655-13.
Full textConference papers on the topic "Biological and Medical Chemistry"
Kaksis, Aris, Agnese Brangule, and Mihails Halitovs. "AN APPROACH TO TEACHING MEDICAL CHEMISTRY THAT HIGHLIGHTS INTERDISCIPLINARY NATURE OF SCIENCE." In 1st International Baltic Symposium on Science and Technology Education. Scientia Socialis Ltd., 2015. http://dx.doi.org/10.33225/balticste/2015.54.
Full textGonzález-Burgos, Elena, Noelia Fraga Matías, Isabel Maria Ureña Vacas, and M. Pilar Gómez-Serranillos. "Biological evaluation of Cetrarioid clade as cholinesterase inhibitors." In 5th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06316.
Full textRatemi, Elaref, and Denis Gravel. "Design, Synthesis and Biological Activity of Selective PHEX Inhibitors." In 1st International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2015. http://dx.doi.org/10.3390/ecmc-1-a044.
Full textKim, Jong H., Kathleen Chan, and Luisa Cheng. "Augmenting the efficacy of antifungal intervention via chemo-biological approaches." In 1st International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2015. http://dx.doi.org/10.3390/ecmc-1-a011.
Full textSalvador Gil, Daniel, and Mª Concepción Gimeno. "New Thiourea-thiazolidine Complexes and Study of their Biological Activity." In 3rd International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/ecmc-3-04665.
Full textAuria-Luna, Fernando, M. Eugenia Marqués-López, M. Concepción Gimeno, and Raquel P. Herrera. "Organocatalytic Synthesis of Chiral 1,4-Dihydropyridines with Potential Biological Properties." In 3rd International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/ecmc-3-04671.
Full textFantacuzzi, Marialuigia. "Synthesis, biological evaluation, and docking study of indole aryl sulfonamides as aromatase inhibitors." In 5th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06361.
Full textSilva-Júnior, Edeildo, Gabriel Passos, Matheus Gomes, Thiago Aquino, Stephannie Souza, João Cavalcante, Elane Santos, Ênio Bassi, and João Araújo-Júnior. "Design, synthesis and in vitro biological evaluation of acrylamide derivatives against Chikungunya virus." In 5th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06379.
Full textMaccallini, Cristina. "Synthesis and biological evaluation of inducible nitric oxide synthase inhibitors as anticancer agents." In 6th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07370.
Full textBaitiche, Milad, Marc Le Borgne, Dounia Sid, Zineb Elbahri, Ferhat Djerboua, and Mokhtar Boutahala. "Development of water-soluble ternary system for enhancing biological activities of mefenamic acid." In 6th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07461.
Full textReports on the topic "Biological and Medical Chemistry"
Price, Barbara B. Chemical Biological Medical Treatment Symposia-III. Fort Belvoir, VA: Defense Technical Information Center, April 2001. http://dx.doi.org/10.21236/ada394695.
Full textSidell, Frederick R., Ernest T. Takafuji, and David R. Franz. Medical Aspects of Chemical and Biological Warfare. Fort Belvoir, VA: Defense Technical Information Center, January 1997. http://dx.doi.org/10.21236/ada398241.
Full textBarr, S. H., ed. Division of Biological and Medical Research research summary 1984-1985. Office of Scientific and Technical Information (OSTI), August 1985. http://dx.doi.org/10.2172/6039516.
Full textBaker, J., D. Bernard, S. Christensen, M. Sale, J. Freda, K. Heltcher, L. Rowe, et al. Biological effects of changes in surface water acid-base chemistry. Office of Scientific and Technical Information (OSTI), January 1990. http://dx.doi.org/10.2172/7255574.
Full textBeebe, Steven J. Second International Symposium on Nonthermal Medical/Biological Treatments using Electromagnetic Fields and Ionized Gases. Fort Belvoir, VA: Defense Technical Information Center, May 2001. http://dx.doi.org/10.21236/ada388316.
Full textSchoenbach, Karl H. First International Symposium on Nonthermal Medical/Biological Treatments using Electromagnetic Fields and Ionized Gases. Fort Belvoir, VA: Defense Technical Information Center, November 1999. http://dx.doi.org/10.21236/ada376636.
Full textCurling, Carl A., and Julia K. Burr. NATO Allied Joint Medical Publication 7: Allied Joint Medical Doctrine for Support to Chemical, Biological, Radiological, and Nuclear (CBRN) Defensive Operations, Final Draft. Fort Belvoir, VA: Defense Technical Information Center, July 2014. http://dx.doi.org/10.21236/ada614619.
Full textSutton, M., B. Andresen, S. Burastero, M. Chiarappa-Zucca, S. Chinn, P. Coronado, A. Gash, J. Perkins, A. Sawvel, and S. Szechenyi. Modern Chemistry Techniques Applied to Metal Behavior and Chelation in Medical and Environmental Systems ? Final Report. Office of Scientific and Technical Information (OSTI), February 2005. http://dx.doi.org/10.2172/15015925.
Full textChung, Myung, Li Dong, Rong Fu, Lance Liotta, Aarthi Narayanan, Emanuel Petricoin, Mark Ross, et al. Rapid Detection of Biological and Chemical Threat Agents Using Physical Chemistry, Active Detection, and Computational Analysis. Office of Scientific and Technical Information (OSTI), January 2007. http://dx.doi.org/10.2172/1049503.
Full textBurr, Julia K., Carl A. Curling, and Lucas A. LaViolet. Exercise "Dread Night": Using Allied Medical Publication-8(C) to Estimate Chemical, Biological, Radiological, and Nuclear (CBRN) Casualties. Fort Belvoir, VA: Defense Technical Information Center, August 2010. http://dx.doi.org/10.21236/ada531193.
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