Academic literature on the topic 'Bioactive heterocyclic compounds'
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Journal articles on the topic "Bioactive heterocyclic compounds"
Luna, Isadora Silva, Rayssa Marques Duarte da Cruz, Ryldene Marques Duarte da Cruz, Rodrigo Santos Aquino de Araújo, and Francisco Jaime Bezerra Mendonça-Junior. "1,4-Dithiane-2,5-diol: A Versatile Synthon for the Synthesis of Sulfur-containing Heterocycles." Current Organic Synthesis 15, no. 8 (December 17, 2018): 1026–42. http://dx.doi.org/10.2174/1570179415666180821154551.
Full textAdak, Laksmikanta, and Tubai Ghosh. "Recent Progress in Iron-Catalyzed Reactions Towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles." Current Organic Chemistry 24, no. 22 (December 18, 2020): 2634–64. http://dx.doi.org/10.2174/1385272824999200714102103.
Full textSharma, Praveen Kumar, Andleeb Amin, and M. Kumar. "Synthetic Methods of Medicinally Important Heterocycles-thiazines: A Review." Open Medicinal Chemistry Journal 14, no. 1 (September 14, 2020): 71–82. http://dx.doi.org/10.2174/1874104502014010071.
Full textAsif, Mohammad. "Biological Potential and Chemical Properties of Pyridine and Piperidine Fused Pyridazine Compounds: Pyridopyridazine a Versatile Nucleus." Asian Journal of Chemistry and Pharmaceutical Sciences 1, no. 1 (November 21, 2016): 29. http://dx.doi.org/10.18311/ajcps/2016/7693.
Full textSultan Alwan, Ensaf, and Rafat Milad Mohareb. "Synthesis of bioactive heterocyclic compounds using camphor." Bulletin of the Chemical Society of Ethiopia 38, no. 4 (April 30, 2024): 1069–76. http://dx.doi.org/10.4314/bcse.v38i4.20.
Full textGe, Tony, and Jean-Christophe Cintrat. "Pyrrolotriazinone as an Underexplored Scaffold in Drug Discovery." Pharmaceuticals 14, no. 12 (December 6, 2021): 1275. http://dx.doi.org/10.3390/ph14121275.
Full textValdomir, Guillermo, María de los Ángeles Fernández, Irene Lagunes, Juan I. Padrón, Víctor S. Martín, José M. Padrón, and Danilo Davyt. "Oxa/thiazole-tetrahydropyran triazole-linked hybrids with selective antiproliferative activity against human tumour cells." New Journal of Chemistry 42, no. 16 (2018): 13784–89. http://dx.doi.org/10.1039/c8nj02388c.
Full textBassam A. Hassan, Hameedi N Nasera, and Maitham M. Abdulridha. "Synthesis and antimicrobial evaluation of fused heterocyclic compound [1,2,4] triazolo [4,3-b][1,2,4,5] tetra zine." International Journal of Research in Pharmaceutical Sciences 10, no. 2 (April 14, 2019): 1254–58. http://dx.doi.org/10.26452/ijrps.v10i2.417.
Full textAkishina, E. A., and Е. А. Dikusar. "Chemical modification of different compounds with nitrogen-containing heterocycles." Proceedings of the National Academy of Sciences of Belarus, Chemical Series 57, no. 3 (September 5, 2021): 356–84. http://dx.doi.org/10.29235/1561-8331-2021-57-3-356-384.
Full textKaran, Ram, Pooja Agarwal, Mukty Sinha, and Neelima Mahato. "Recent Advances on Quinazoline Derivatives: A Potential Bioactive Scaffold in Medicinal Chemistry." ChemEngineering 5, no. 4 (October 26, 2021): 73. http://dx.doi.org/10.3390/chemengineering5040073.
Full textDissertations / Theses on the topic "Bioactive heterocyclic compounds"
Mojally, Mariam. "DNA binding studies of fluorinated bioactive heterocyclic compounds." Thesis, Loughborough University, 2015. https://dspace.lboro.ac.uk/2134/16732.
Full textDey, Sourav. "Synthesis of bioactive organic heterocyclic compounds using novel catalysts." Thesis, University of North Bengal, 2022. http://ir.nbu.ac.in/handle/123456789/5160.
Full textTrippier, Paul Charles. "Synthesis of highly substituted heterocycles : the oxazolomycins." Thesis, University of Oxford, 2006. http://ora.ox.ac.uk/objects/uuid:b758987c-7a0c-4c1b-982c-61b4d383680a.
Full textMitra, Bijeta. "Development of new protocols towards construction of bioactive hetero cyclic compounds." Thesis, University of North Bengal, 2021. http://ir.nbu.ac.in/handle/123456789/4368.
Full textKilburn, John Paul. "Novel solid-phase synthesis strategies for the preparation of heterocycles and guanidines." Thesis, Open University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247056.
Full textFerrazzano, Lucia <1989>. "Five-Membered Nitrogen Heterocycle Derivatives as Core Structures for the Synthesis of Bioactive Compounds Classes." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amsdottorato.unibo.it/7956/1/PhD%20thesis%20Lucia%20Ferrazzano%20AMS%20dottorato.pdf.
Full textFrija, L. "Investigation of structural effects on the reactivity of heterocyclic bioactive compounds." Doctoral thesis, 2008. http://hdl.handle.net/10400.1/856.
Full textIn the course of this investigation, structural effects on the reactivity of a series of heterocyclic compounds, in particular tetrazole and benzisothiazole derivatives, submitted to different chemical environments, were explored. The photochemistry of several representative tetrazoles was considered in solution and for the compounds trapped in a rigid matrix of solidified argon at cryogenic temperatures. UV-excitation resulted in photofragmentation of tetrazoles with a wide range of exit channels. Important mechanistic questions concerning the photodecomposition of allyl-tetrazolyl derivatives in different solvents were answered, and new synthetic methodologies for the preparation of heterocyclic compounds, such as pyrimidinones or oxazines, from allyl-tetrazoles, were developed. For the matrix-isolated compounds, since the obtained fragments in general stay in the matrix cage where they are formed, no subsequent cross-reactions involving species resulting from photolysis of different reactant molecules can occur. This fact introduced a useful simplification for the interpretation of the reaction mechanisms. FTIR spectroscopy provided experimental frequencies and intensities of characteristic absorptions of the matrix-isolated chemical species, both for reagents and photoproducts. The analysis of experimental data was assisted by their direct comparison with the vibrational spectra theoretically calculated for the single molecule in vacuum. Spectroscopic characterization of a number of relatively unusual or highly reactive molecules, formed from photolysis of matrix-isolated tetrazoles, is presented for the first time. Novel tetrazolyl and benzisothiazolyl naphthylmethylic ethers were synthesized and the development of experimental conditions for their palladium-catalysed hydrogenolysis, using a hydrogen donor or molecular hydrogen, was carried out successfully. Structural effects on the reactivity of the heteroaromatic ethers were investigated. Furthermore, new benzisothiazole-tetrazolyl derivatives differing on the spacer-group used for linkage of the two heterocyclic systems were designed, produced and tested as multidentate ligands in coordination reactions with transition-metal complexes.
Carvalho, Maria Solange Dantas de. "New heterocyclic bioactive fluorescent compounds: spectroscopic studies of DNA interactions and encapsulation in nanoliposomes." Doctoral thesis, 2013. http://hdl.handle.net/1822/25580.
Full textSpectroscopic studies (absorption and steady-state fluorescence) of potential antitumoral heteroaryl and heteroannulated indoles, benzothienopyran-1-ones, methyl 3-amino-6-heteroarylthieno[3,2-b]pyridine-2-carboxylates, tetracyclic thieno[3,2-b]pyridine derivatives and benzothienoquinolines, synthesized in our research group, were performed in solvent of different polarities. Generally, all the compounds presented a solvent sensitive emission with significant red-shifts in polar solvents, pointing out for their potential use as solvatochromic probes. The antitumoral potential of some of the compounds was evaluated by the growth inhibition of human tumor cell lines in collaboration with the Faculty of Pharmacy of the University of Porto. The spectroscopic properties of the compounds were also evaluated when incorporated in liposomes of neat lipids and lipid mixtures of different formulations, including, Egg-PC (egg yolk phosphatidylcholine), DPPC (dipalmitoyl phosphatidylcholine), DPPG (dipalmitoyl phosphatidylglycerol), DMPG (dimyristoyl phosphatidylglycerol), DOPE (dioleoyl phosphatidylethanolamine), DSPE-PEG (Distearoyl phosphatidylethanolamine-polyethylene glycol), DODAB (Dioctadecyldimethylammonium bromide) and cholesterol. Fluorescence steady-state anisotropy measurements allowed monitoring the location and behaviour of the compounds in the liposomes. In most cases, they showed to be located mainly in the hydrophobic region of the lipid bilayers, experiencing differences in fluidity between the rigid gel and the liquid-crystalline phases. These studies of the antitumoral compounds encapsulation were made having in mind future drug delivery applications. The mean size, size-distribution and zeta-potential of the liposomes incorporating the most promising antitumoral compounds, were determined by DLS (Dynamic Light Scattering). Almost all the liposomes with the incorporated compounds have shown diameters under 165nm and, with some formulations like DPPC:DMPG:DSPE-PEG (1:1:0.1), small diameters (below 100nm), low polydispersity and reasonable negative zeta-potential values were obtained for two of the methyl 3-amino-6- heteroarylthieno[3,2-b]pyridine-2-carboxylates studied. In order to evaluate the interaction with nucleic acids, the binding modes of the tetracyclic planar fluorescent thieno[3,2-b]pyridine derivatives and of the benzothienoquinolines to salmon sperm DNA and/or to synthetic double-stranded (ds) heteropolynucleotides were studied using spectroscopic methods which allowed the determination of intrinsic binding constants (Ki) and binding site sizes (n). Fluorescence quenching experiments with iodide ion were also performed in order to distinguish between the different binding modes of the compounds to the nucleic acids studied, since intercalated molecules are less accessible to anionic quenchers due to electrostatic repulsion with negatively charged nucleic acids. All the compounds interact with DNA and polynucleotides either by intercalation or groove binding. The latter seems to be the main type of interaction of these compounds with nucleic acids.
Foram realizados estudos espetroscópicos (absorção e fluorescência em estado estacionário) de heteroarilindoles e indoles heteroanelados, benzotienopiran-1-onas, 3-amino-6-heteroariltieno[3,2-b]piridina-2-carboxilatos de metilo, derivados tetracíclicos de tieno[3,2-b]piridinas e benzotienoquinolinas com potencial antitumoral, sintetizados no nosso grupo de investigação, em solventes de diferentes polaridades. De um modo geral, todos os compostos apresentaram uma emissão sensível ao solvente com significativos desvios para vermelho em meios polares, indicando a sua potencial utilização como sondas solvatocrómicas. O potencial antitumoral de alguns dos compostos foi avaliado através da inibição do crescimento de linhas celulares tumorais humanas em colaboração com a Faculdade de Farmácia da Universidade do Porto. As propriedades espetroscópicas foram também avaliadas para os compostos incorporados em lipossomas de lípidos puros e misturas lipídicas de diferentes formulações, incluindo, Egg-PC (fosfatidilcolina do ovo), DPPC (dipalmitoilfosfatidilcolina), DPPG (dipalmitoilfosfatidilglicerol), DMPG (dimiristoilfosfatidilglicerol), DOPE (dioleoilfosfatidiletanolamina), DSPE-PEG (Distearoil fosfatidiletanolamina-polietilenoglicol), DODAB (Brometo de dioctadecildimetilamónio) e colesterol. Medidas de anisotropia de fluorescência em estado estacionário permitiram monitorizar a localização dos compostos nos lipossomas. Na maioria dos casos, os compostos mostraram estar localizados maioritariamente na região hidrofóbica da bicamada lipídica, sentindo diferenças de fluidez entre a fase-gel e a fase líquidocristalina dos lípidos. Estes estudos de encapsulação dos compostos antitumorais foram realizados tendo em vista aplicações futuras de libertação de fármacos. O tamanho médio, distribuição de tamanhos e potencial-zeta dos lipossomas incorporando os compostos antitumorais mais promissores foram avaliados através de medidas de DLS (Difusão de Luz Dinâmica). A maioria dos lipossomas mostrou possuir diâmetros menores que 165nm e, algumas formulações como DPPC:DMPG:DSPE-PEG (1:1:0.1), exibiram tamanhos menores que 100nm e baixa polidispersividade. Valores de potencial-zeta razoavelmente negativos foram obtidos para dois dos 3-amino-6- heteroariltieno[3,2-b]piridina-2-carboxilatos de metilo estudados. Para avaliar a interação com os ácidos nucleicos, os modos de ligação dos derivados tetracíclicos fluorescentes planares de tieno[3,2-b]piridinas e de benzotienoquinolinas ao DNA de esperma de salmão e heteropolinucleótidos sintéticos de cadeia dupla, foram estudados usando métodos espetroscópicos que permitiram a determinação das constantes de ligação (Ki) e tamanho dos sítios de ligação (n). Medidas de inibição de fluorescência pelo ião iodeto foram também realizadas para distinguir entre os diferentes modos de ligação dos compostos aos ácidos nucleicos estudados, uma vez que as moléculas intercaladas estão menos acessíveis a inibidores aniónicos devido às repulsões eletrostáticas com os ácidos nucleicos carregados negativamente. Todos os compostos interatuam com o DNA e polinucleótidos ou por intercalação, ou por ligação nos sulcos (grooves). Este modo de ligação parece ser o tipo de interação predominante dos compostos com os ácidos nucleicos.
Krishnan, Anand. "Synthesis of Bioactive Nitrogen Heterocycles and Functionalized Nanomaterials for Biological and Catalytic Applications." Thesis, 2015. http://hdl.handle.net/10321/1181.
Full textAromatic heterocycles are highly important structural units found in a large number of biologically active natural compounds, pharmaceuticals and catalytic compounds. They have a crucial role in organic syntheses, which results in the generation of high value products. Among heterocycles, those containing nitrogen are the most indispensable structural motifs and are widely used against dreaded diseases such as Malaria, TB, HIV/AIDS and Cancer. The inclusion of highly electronegative atoms such as fluorine in these organic molecules render them very reactive towards proteins. Furthermore these molecules exhibit strong interactions with surfaces of quantum range particles of elemental gold. Various approaches for the synthesis of novel gold nanoparticles linked to potent bioactive molecules are documented and their application as drug delivery systems are of immense value to human health. Also many chemical and physical methods are available for the synthesis of gold, silver and palladium nanoparticles however these methods are usually laborious and produce toxic by-products. The green approach is to use plant extracts to synthesise various size and shape nanoparticles which could be used in biological and catalytic systems. A simple one-pot two component and three component reaction using formyl quinoline, 2-aminothiophenol, thiosemicarbazone and trifluoromethylbenzaldehyde as a reactant to synthesise quinoline, pyridine and pyran based bioactive small molecules; these products are a quinoline type bearing a benzothiazole moiety, quinoline thio semicarbazone ligand, fluorine substituted dihydro pyridine, fluorine substituted dihydropyran and fluorine substituted pyridine derivatives. In total, fifteen compounds were synthesized eleven of which were novel; all compounds were characterized by spectroscopic techniques. In vitro anti-bacterial activities of the synthesized compounds were investigated against a representative panel of pathogenic strains. Compounds 6, 7, 8, 11 and 13 exhibited excellent anti-bacterial activity compared with first line drugs. Potent p53–MDM2 interaction inhibitors 2-thio-1,2-dihydroquinoline-3-carbaldehyde thiosemicarbazone and fluorine substituted new pyridine scaffold were successfully identified by structure-based design. An efficient one-pot four component route to the synthesis of trifluorinated pyrrolophenanthroline and fluoroquinoline pyrrolophenanthrolines was designed. In this reaction 1-butyl-2,3-dimethylimidazolium tetrafluoroborate ionic liquid (DMTIL) was used as a reaction medium; no catalyst was required. The structure of the pyrrolophenanthrolines was deduced by IR and NMR analysis. These compounds were studied with Bovine Serum Albumin (BSA) through molecular docking. Hydrophopic, electrostatic and hydrogen bonding interaction played a crucial role in the binding to sub domain of BSA. Interaction studies of DMTIL with BSA by emission, absorption, synchronous fluorescence, circular dichroism (CD) and three dimensional emission (3D) spectroscopic techniques were under taken. The results from emission titration experiments revealed the existence of a strong interaction between BSA and DMTIL ionic liquid. It showed that compounds with lesser number of hydrogen bonds are found to be more active which is attributed to hydrophobic interaction and electrostatic interaction which also played a vital role in DMTIL binding to sub domain IB of BSA. A novel copper-loaded boron nitride nanosheet (Cu/BN) catalyst was prepared and fully characterized. It was used as an efficient and chemoselective catalysts for the synthesis of α-aminophosphonates by the Kabachnik-Fields reaction; twenty one α-aminophosphonates were synthesised. The enhanced catalytic activity and product yield was attributed to the increase of surface acidity. Overall, this methodology offered competitive advantages such as recyclability of the catalyst without further purification or without using additives or cofactors, low catalyst loading, broad substrate applicability and high yields. The application of this new nanocatalyst in organic synthesis will provide a novel pathway for the synthesis of pharmaceutically important compounds. Gold nanoparticle surfaces were modified with self-assembled monolayers of important thiol and disulfide bioactive molecules since considerable interest is due to their potential application as anti-cancer agents. Herein, a carbazole was conjugated to lipoic acid by using an amide coupling catalyst HBTU and DIEA reaction. The structure of the carbazole thio octanic acid (CTN) was identified by IR and NMR. CTN was attached to the gold nanoparticles surface and the capping behaviour was characterized by UV-vis spectroscopy, TEM, DLS and FTIR. The cytotoxicity of CTNAuNPs on A549 cell lines was determined using the MTT assay. The results suggest CTN and CTNAuNPs possess anti-proliferative properties in the cancerous A549 cells. Furthermore a dual thiol ligand was synthesized by using equimolar 4-aminothiophenol (4-ATP) and amino oxadiazole thiol (AXT). This dual ligand was attached to the gold nanoparticles surface (DTAu) and the capping behaviour was characterized by UV-vis spectroscopy, TEM, DLS and FTIR. The cytotoxicity of DTAu on A549 cell lines was determined using the MTT assay. The results suggest dual ligands (4-ATP, AXT) and DTAu possess anti-proliferative properties in the cancerous A549 cells. South African indigenous plants and agroforestry waste were also used in the synthesis of silver, gold and palladium nanoparticles (NPs). Green protocols such as the use of environmentally benign solvents and non-hazardous reagents were an added advantage to physical and chemical means. Furthermore these reactions were rapid and the size and shape of the NPs could be manipulated by choosing the correct medium. The formulation of natural medicinal compounds capped onto NPs was assessed for their anti-cancer activity, in A549 lung cancer line, and catalytic reduction of dyes and nitrobenzene derivatives were studied. These NPs displayed: Significant cytotoxicity to lung cancer cells with minimal effect on normal healthy cells. Outstanding catalytic reduction of pharmaceutical and textile waste effluents such as dyes and nitro aromatic compounds. In addition, palladium nanoparticles containing capped Moringa olifera compounds were used effectively in the Suzuki coupling reaction of iodobenzene and phenylboronic acid. The reaction was rapid and was conducted in an aqueous medium.
Books on the topic "Bioactive heterocyclic compounds"
Eguchi, Shoji. Bioactive heterocycles. Edited by Eguchi Shoji. Berlin: Springer, 2006.
Find full textKhan, Mahmud Tareq Hassan. Bioactive Heterocycles IV. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2007.
Find full textKhan, Mahmud Tareq Hassan. Bioactive Heterocycles III. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2007.
Find full textKhan, Mahmud Tareq Hassan. Bioactive Heterocycles V. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2007.
Find full textMotohashi, Noboru. Bioactive Heterocycles VI: Flavonoids and Anthocyanins in Plants, and Latest Bioactive Heterocycles I. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2008.
Find full textMotohashi, Noboru. Bioactive Heterocycles VII: Flavonoids and Anthocyanins in Plants, and Latest Bioactive Heterocycles II. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009.
Find full textLamberth, Clemens, and Jürgen Dinges, eds. Bioactive Heterocyclic Compound Classes. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.
Full textDinges, Jürgen, and Clemens Lamberth, eds. Bioactive Heterocyclic Compound Classes. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664450.
Full textBioactive Marine Heterocyclic Compounds. MDPI, 2021. http://dx.doi.org/10.3390/books978-3-0365-2753-6.
Full textUsami, Yoshihide. Bioactive Marine Heterocyclic Compounds. Mdpi AG, 2021.
Find full textBook chapters on the topic "Bioactive heterocyclic compounds"
Ata, Athar, and Samina Naz. "Synthesis of Bioactive Heterocyclic Compounds." In Greener Synthesis of Organic Compounds, Drugs and Natural Products, 137–50. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003089162-8.
Full textWong-Paz, Jorge E., Sylvain Guyot, Juan C. Contreras-Esquivel, Pedro Aguilar-Zárate, Raúl Rodríguez-Herrera, and Cristóbal N. Aguilar. "Separation of Coffee Pulp Bioactive Phenolic Compounds by MPLC Fractionation and Identification by HPLC-ESI-MS." In Modern Green Chemistry and Heterocyclic Compounds, 217–28. Series statement: Innovations in physical chemistry: monographic series: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780367276942-9.
Full textDandia, Anshu, Shyam L. Gupta, and Shuchi Maheshwari. "Molecular Iodine: Mild, Green, and Nontoxic Lewis Acid Catalyst for the Synthesis of Heterocyclic Compounds." In Green Chemistry: Synthesis of Bioactive Heterocycles, 277–327. New Delhi: Springer India, 2014. http://dx.doi.org/10.1007/978-81-322-1850-0_10.
Full textLamberth, Clemens, and Jürgen Dinges. "The Significance of Heterocycles for Pharmaceuticals and Agrochemicals*." In Bioactive Heterocyclic Compound Classes, 1–20. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.ch1.
Full textLamberth, Clemens. "Morpholine Fungicides for the Treatment of Powdery Mildew." In Bioactive Heterocyclic Compound Classes, 119–27. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.ch10.
Full textWorthington, Paul. "Sterol Biosynthesis Inhibiting Triazole Fungicides." In Bioactive Heterocyclic Compound Classes, 129–45. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.ch11.
Full textLamberth, Clemens. "Methionine Biosynthesis-Inhibiting Anilinopyrimidine Fungicides." In Bioactive Heterocyclic Compound Classes, 147–54. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.ch12.
Full textLamberth, Clemens. "Phenylpyrrole Fungicides." In Bioactive Heterocyclic Compound Classes, 155–62. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.ch13.
Full textLamberth, Clemens. "Broad-Spectrum Fungicidally Active Pyrimidinyldioxy Strobilurins Inhibiting the Respiratory Chain." In Bioactive Heterocyclic Compound Classes, 163–74. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.ch14.
Full textWalter, Harald. "Pyrazole Carboxamide Fungicides Inhibiting Succinate Dehydrogenase." In Bioactive Heterocyclic Compound Classes, 175–93. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2012. http://dx.doi.org/10.1002/9783527664412.ch15.
Full textConference papers on the topic "Bioactive heterocyclic compounds"
Verdes, Anastasia, Elena Gorincioi, Lucian Lupascu, Gheorghe Duca, and Fliur Macaev. "Targeting the bioactive dihydropyrimidines by ecofriendly procedure of biginelli reaction: study case of monastrol." In Scientific seminar with international participation "New frontiers in natural product chemistry". Institute of Chemistry, Republic of Moldova, 2023. http://dx.doi.org/10.19261/nfnpc.2023.ab24.
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