Relevant bibliographies by topics / Bio-/nano-interface

Academic literature on the topic 'Bio-/nano-interface'

Author: Grafiati
Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "Bio-/nano-interface"

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Ramsden, J. J. "The bio–nano interface." Nanotechnology Perceptions 5, no. 2 (July 30, 2009): 151–65. http://dx.doi.org/10.4024/n11ra09a.ntp.05.02.

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Leszczynski, Jerzy. "Nano meets bio at the interface." Nature Nanotechnology 5, no. 9 (September 2010): 633–34. http://dx.doi.org/10.1038/nnano.2010.182.

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Prinz Setter, Ofer, and Ester Segal. "Halloysite nanotubes – the nano-bio interface." Nanoscale 12, no. 46 (2020): 23444–60. http://dx.doi.org/10.1039/d0nr06820a.

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Al-Mufti, A. Wesam, U. Hashim, Md Mijanur Rahman, and Tijjani Adam. "Nano–bio interface: the characterization of functional bio interface on silicon nanowire." Microsystem Technologies 21, no. 8 (July 20, 2014): 1643–49. http://dx.doi.org/10.1007/s00542-014-2241-5.

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Mohapatra, Shyam S. "EDITORIAL: NANOBIO COLLABORATIVE EXPLORES NANO-BIO INTERFACE." Technology & Innovation 13, no. 1 (January 1, 2011): 1–3. http://dx.doi.org/10.3727/194982411x13003853540117.

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Torimitsu, Keiichi. "Nano-Bio Interface - Neural & Molecular Functions." Advances in Science and Technology 53 (October 2006): 91–96. http://dx.doi.org/10.4028/www.scientific.net/ast.53.91.

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This paper briefly introduces the nano-bio related-research being carried out in our research group. The work is based on a fusion of neuroscience and bio-molecular science with nanotechnology. This interdisciplinary research is extremely promising for creating a new technology and developing a new knowledge. Nano-bio research could be a key to understanding the signal processing mechanism that lies behind memory and the learning system in our brain. Developing a novel biocompatible device that runs with biological functions is one of our research goals.
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Rouse, Ian, David Power, Erik G. Brandt, Matthew Schneemilch, Konstantinos Kotsis, Nick Quirke, Alexander P. Lyubartsev, and Vladimir Lobaskin. "First principles characterisation of bio–nano interface." Physical Chemistry Chemical Physics 23, no. 24 (2021): 13473–82. http://dx.doi.org/10.1039/d1cp01116b.

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We present a multiscale computational approach for the first-principles study of bio-nano interactions. Using titanium dioxide as a case study, we evaluate the affinity of titania nanoparticles to water and biomolecules through atomistic and coarse-grained techniques.
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Wang, Jing, Waseem Akthar Quershi, Yiye Li, Jianxun Xu, and Guangjun Nie. "Analytical methods for nano-bio interface interactions." Science China Chemistry 59, no. 11 (October 14, 2016): 1467–78. http://dx.doi.org/10.1007/s11426-016-0340-1.

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Liang, Jieying, and Kang Liang. "Nano-bio-interface engineering of metal-organic frameworks." Nano Today 40 (October 2021): 101256. http://dx.doi.org/10.1016/j.nantod.2021.101256.

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Hennig, Andreas, Sheshanath Bhosale, Naomi Sakai, and Stefan Matile. "CD Methods Development at the Bio-Nano Interface." CHIMIA International Journal for Chemistry 62, no. 6 (June 25, 2008): 493–96. http://dx.doi.org/10.2533/chimia.2008.493.

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Dissertations / Theses on the topic "Bio-/nano-interface"

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Neibert, Kevin. "Quantum Dots-interactions at the nano-bio interface." Thesis, McGill University, 2014. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=122999.

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Nanotechnology is an area of research that lies at the interface of physics, chemistry, engineering and biotechnology. The last decade has seen nanotechnology become a household term, as nano-scale products, known as nanoparticles, have become diverse in nature and form. Despite their immense promise, the widespread application of nanoparticles is currently limited due to their questionable biocompatibility and unclear consequences on cells and other biological components. We have selected fluorescent nanocrystals, called quantum dots (QDs), to investigate the interactions between nanoparticles and the biological environment, due to their superior optical properties. In the present studies, the mechanisms underlying the adaptive cell response to QDs were examined in multiple model cell lines. We observed significant morphological and functional changes at the cellular and subcellular levels following long term exposure to uncapped QDs. We showed that QD-induced toxicity included the production of reactive oxygen and nitrogen species as well as disruption of mitochondrial function. In addition, we found a novel role for transcription factor EB (TFEB), a master regulator of lysosome biogenesis in the successful cellular adaptation process. We showed that modifications to the QD surface can significantly decrease its toxicity, and in some cases, render the QDs non-toxic. Understanding the mechanisms of cellular adaptation to QDs is a first step for the establishment of protocols to evaluate the safety of other nanomaterials. We then investigated the effects of QD surface properties and how they contribute to particle uptake by using QDs with the same core, but with different surface functionalization. We demonstrated that QD surface charge plays an important role in internalization in two different human cell lines. In addition, we provided evidence for the involvement of several overlapping modes of uptake and export from the cell. Finally, we systematically investigated the effects of QD surface properties on particle stability in biological media. We found that serum proteins were differently adsorbed to the particle surface, and this played a key role in determining the primary mode of internalization. Taken together, the results from this work contribute to the development of nano-scale materials in two main ways:1)by presenting in vitro measures as the first step in the evaluation of nanomaterial safety.2)by demonstrating how surface charge and ligand properties drive specific modes of internalization The findings presented herein promote understanding of the intricacies at the nano-bio interface and provide guiding principles for sensible nanoparticle design, with careful consideration for size, shape and surface charge.
La nanotechnologie se trouve à l'interface de la physique, de la chimie, de l'ingénierie et de la biotechnologie. Au cours de la dernière décennie, les produits de taille nanométrique, appelées nanoparticules, sont devenus de nature et forme de plus en plus diversifiée menant à un grand essor de la nanotechnologie. Malgré leur immense potentiel, l'application généralisée des nanoparticules est actuellement limitée en raison du manque d'information sur leur biocompatibilité et leurs conséquences néfastes sur les cellules et autres composants biologiques. Nous avons sélectionné des nanocristaux fluorescents de propriétés optiques supérieures, appelés points quantiques (QD), afin d'étudier les interactions entre les nanoparticules et l'environnement biologique. Dans cette étude, les mécanismes sous-jacents de la réponse adaptative des cellules lors de l'exposition à des points quantiques ont été examinés dans plusieurs lignées cellulaires. Nous avons observé des changements morphologiques et fonctionnels importants aux niveaux cellulaire et subcellulaire suite à une exposition de long terme à des points quantiques non-revêtu de coque. Nous avons démontré que la toxicité induite par ces QD implique la production d'espèces réactives de l'oxygène et de l'azote ainsi que des perturbations de la fonction mitochondriale. Nous avons également découvert un nouveau rôle pour transcription factor EB (TFEB), un régulateur clé de la biogenèse des lysosomes, dans la réussite du processus d'adaptation cellulaire. Nous avons montré que la présence d'une coque recouvrant les QD ainsi que des modifications à leur surface peuvent diminuer significativement leur toxicité, et dans certains cas, les rendre non-toxiques. La compréhension des mécanismes d'adaptation cellulaire en réaction aux points quantiques est essentielle au développement de procédés évaluant la sécurité d'autres nanomatériaux.Nous avons par la suite étudié l'effet des propriétés de surface des QD et comment elles contribuent à l'absorption des particules. Nous avons utilisé des points quantiques de même noyau mais ayant des modifications de surface distinctes. Nous avons démontré que la charge de surface des QD joue un rôle important dans leur internalisation cellulaire dans deux lignés de cellules humaines différentes. De plus, nous avons montré que plusieurs modes d'importation et d'exportation de la cellule étaient impliqués dans ce processus. Enfin, nous avons étudié systématiquement les effets des propriétés de surface des QD sur la stabilité des particules dans les milieux biologiques. Nous avons découvert que les protéines du sérum sont différemment adsorbées à la surface des particules ce qui joue un rôle déterminant dans le mode d'intériorisation principal.En conclusion, ces résultats aident au développement de matériaux d'échelle nanométrique de deux façons:1 ) en promouvant les modèles in vitro comme une première étape dans l'évaluation de la sécurité des nanomatériaux.2 ) en démontrant un lien entre la charge de surface ainsi que les propriétés des ligands et les modes spécifiques d'internalisation cellulaire.Les résultats présentés ici contribuent à la compréhension de la complexité de l'interface nano-bio et fournissent des principes directeurs pour la conception minutieuse de nanoparticules, avec une attention particulière pour la taille, la forme et la charge de surface.
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Kozyra, Jerzy Wieslaw. "Computation and programmability at the nano-bio interface." Thesis, University of Newcastle upon Tyne, 2017. http://hdl.handle.net/10443/3694.

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The manipulation of physical reality on the molecular level and construction of devices operating on the nanoscale has been the focal point of nanotechnology. In particular, nanotechnology based on DNA and RNA has a potential to nd applications in the eld of Synthetic Biology thanks to the inherent compatibility of nucleic acids with biological systems. Sca olded DNA origami, proposed by P. Rothemund, is one of the leading and most successful methods in which nanostructures are realised through rational programming of short 'staple' oligomers which fold a long single-stranded DNA called the 'sca old' strand into a variety of desired shapes. DNA origami already has many applications; including intelligent drug delivery, miniaturisation of logic circuits and computation in vivo. However, one of the factors that are limiting the complexity, applicability and scalability of this approach is the source of the sca old which commonly originates from viruses or phages. Furthermore, developing a robust and orthogonal interface between DNA nanotechnology and biological parts remains a signi cant challenge. The rst part of this thesis tackles these issues by challenging the fundamental as- sumption in the eld, namely that a viral sequence is to be used as the DNA origami sca old. A method is introduced for de novo generation of long synthetic sequences based on De Bruijn sequence, which has been previously proposed in combinatorics. The thesis presents a collection of algorithms which allow the construction of custom- made sequences that are uniquely addressable and biologically orthogonal (i.e. they do not code for any known biological function). Synthetic sca olds generated by these algorithms are computationally analysed and compared with their natural counter- parts with respect to: repetition in sequence, secondary structure and thermodynamic addressability. This also aids the design of wet lab experiments pursuing justi cation and veri cation of this novel approach by empirical evidence. The second part of this thesis discusses the possibility of applying evolutionary op- timisation to synthetic DNA sequences under constraints dictated by the biological interface. A multi-strand system is introduced based on an alternative approach to DNA self-assembly, which relies on strand-displacement cascades, for molecular data storage. The thesis demonstrates how a genetic algorithm can be used to generate viable solutions to this sequence optimisation problem which favours the target self- assembly con guration. Additionally, the kinetics of strand-displacement reactions are analysed with existing coarse-grained DNA models (oxDNA). This thesis is motivated by the application of scienti c computing to problems which lie on the boundary of Computer Science and the elds of DNA Nanotechnology, DNA Computing and Synthetic Biology, and thus I endeavour to the best of my ability to establish this work within the context of these disciplines.
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Schwaminger, Sebastian Patrick [Verfasser]. "Nano-bio interactions at the aqueous interface of iron oxide nanoparticles / Sebastian Patrick Schwaminger." München : Verlag Dr. Hut, 2017. http://d-nb.info/1149580178/34.

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Brown, Katherine Alice. "Noncovalent adsorption of nucleotides in gold nanoparticle DNA conjugates : bioavailability at the bio-nano interface." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/44866.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Biological Engineering Division, 2008.
Includes bibliographical references (p. 82-92).
The practical viability of biomolecule-nanostructure hybrids depends critically on the functional and structural stability of biomolecules in application environments. Noncovalent interactions of biochemical functional groups with nanostructure surfaces can significantly disrupt biomolecular structure and function. We report a systematic study of the effect of DNA sequence on the binding interaction between gold nanoparticles and thiolated DNA (AuNp-DNA). Base specific noncovalent nucleotide adsorption on gold surfaces can affect nucleotide bioavailability in solution. Systematic investigation of DNA oligonucleotide sequence, the location of specific sequence motifs, and the effect of nanoparticle size was performed. Sequence effects on DNA coverage and oligonucleotide adsorption affinities.were studied by Langmuir isotherm analysis. The nanoparticle coverage at saturating concentrations of thiolated DNA varied with oligonucleotide sequence. Saturation coverages correlated well with complement hybridization efficiency. From this we concluded that noncovalent interactions between nucleotides and the particle surface effect both hybridization and DNA coverage and adsorption. This hypothesis was confirmed by chemical treatment of the particle surface to eliminate noncovalent interactions. Upon treatment the effect of sequence on hybridization efficiency was removed. The effect of sequence is not consistent across nanoparticle sizes. Different bases show the highest saturation coverages and hybridization efficiencies on different AuNp sizes. These results allow for sequence selection guidelines based on AuNp size for sizes ranging from 4-11nm. For smaller particles (<5nm) adenine rich sequences show the highest saturation coverage and hybridization efficiency.
(cont.) For mid-sized particles (~7.5nm), guanine sequences show the highest saturation coverage and hybridization efficiency. Larger particles (>10nm) show little sequence dependent behavior and are likely the best choice for uses where sequence choice is limited. Sequence selection based on these guidelines will provide AuNp-DNA conjugates with the highest possible oligonucleotide bioavailability, maximizing their utility in biotechnology applications.
by Katherine A. Brown.
Ph.D.
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Li, Kungang. "Investigation of the aggregation of nanoparticles in aqueous medium and their physicochemical interactions at the nano-bio Interface." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53416.

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Owing to their unique physical, chemical, and mechanical properties, nanoparticles (NPs) have been used, or are being evaluated for use, in many fields (e.g., personal care and cosmetics, pharmaceutical, energy, electronics, food and textile). However, concerns regarding the environmental and biological implications of NPs are raised alongside the booming nanotechnology industry. Numerous studies on the biological effect of NPs have been done in the last decade, and many mechanisms have been proposed. In brief, mechanisms underlying the adverse biological effect caused by NPs can be summarized as: (i) indirect adverse effect induced by reactive oxygen species (ROS) generated by NPs, (ii) indirect adverse effect induced by released toxic ions, and (iii) adverse effect induced by direct interactions of NPs with biological systems. Up to now, most efforts have been focused on the first two mechanisms. In contrast, adverse biological effects induced by direct nano-bio interactions are the least researched. This is largely because of the complexity and lack of suitable techniques for characterizing the nano-bio interface. This dissertation aims at advancing our understanding of the nano-bio interactions leading to the adverse biological effect of NPs. Specifically, it is comprised of three parts. Firstly, because the aggregation of NPs alters particle size and other physicochemical properties of NPs, the property of NPs reaching and interacting with biological cells is very likely different from that of what we feed initially. Consequently, as the first step and an essential prerequisite for understanding the biological effect of NPs, NP aggregation is investigated and models are developed for predicting the stability and the extent of aggregation of NPs. Secondly, interactions between NPs and cell membrane are studied with paramecium as the model cell. Due to the lack of cell wall, the susceptible cell membrane of paramecium is directly exposed to NPs in the medium. The extent and strength of direct nano-cell membrane interaction is evaluated and quantified by calculating the interfacial force/interaction between NPs and cell membrane. A correlation is further established between the nano-cell membrane interaction and the lethal acute toxicity of NPs. We find NPs that have strong association or interaction with the cell membrane tend to induce strong lethal effects. Lastly, we demonstrate systematic experimental approaches based on atomic force microscope (AFM), which allows us to characterize nano-bio interfaces on the single NP and single-molecular level, coupled with modeling approaches to probe the nano-DNA interaction. Using quantum dots (QDs) as a model NP, we have examined, with the novel application of AFM, the NP-to-DNA binding characteristics including binding mechanism, binding kinetics, binding isotherm, and binding specificity. We have further assessed the binding affinity of NPs for DNA by calculating their interaction energy on the basis of the DLVO models. The modeling results of binding affinity are validated by the NP-to-DNA binding images acquired by AFM. The investigation of the relationship between the binding affinity of twelve NPs for DNA with their inhibition effects on DNA replication suggests that strong nano-DNA interactions result in strong adverse genetic effects of NPs. In summary, this dissertation has furthered our understanding of direct nano-bio interactions and their role in the biological effect of NPs. Furthermore, the models developed in this dissertation lay the basis for building an “ultimate” predictive model of biological effects of NPs that takes into account multiple mechanisms and their interactions, which would save a lot of testing costs and time in evaluating the risk of NPs.
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Wurster, Eva-Christina [Verfasser], and M. [Akademischer Betreuer] Breunig. "Layer-by-Layer assembled thin films for drug delivery: Interactions at the nano-bio interface / Eva-Christina Wurster. Betreuer: M. Breunig." Regensburg : Universitätsbibliothek Regensburg, 2016. http://d-nb.info/110322901X/34.

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Chen, Chiao-Yu, and 陳喬郁. "Isolation of monoclonal antibody with binding activity specific to bio-nano interface." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/829k33.

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碩士
國立交通大學
材料科學與工程學系奈米科技碩博士班
104
There are more and more application of nano-materials in medicine and biotechnology. The interest in nano-systems for biological applications is continuously growing. To explore the potential of nano-material in the application of drug delivery, artificial implants, and bio-electronics, the fundamental rules underlining the bio-nano interaction should be carefully investigated. Understanding the bio-nano interface is the key to develop and better use of bionanotechnology. I have demonstrated several specific bio-nano interface previously. I also showed that antibody can recognize gold nanoparticles. Our approach is to develop monoclonal antibody against gold nanoparticles which will serve as the base for further biophysical study and applications. The result indicated that I was able to isolate monoclonal antibody that still maintained the specific binding activity. The single-molecule electrical conductance of the protein transistor made by this antibody revealed the dynamic binding which confirmed the thermodynamics of the binding. Production of monoclonal antibodies consists of four steps: immunizing the animal usually a mouse, obtaining immune cells from the spleen of the immunized mouse, fusing the spleen cells with myeloma cells to obtain hybridomas, and selecting the hybridoma cell line producing the desired monoclonal antibody. I immunized mice using gold nanoparticles. The spleens of positive mice were fused with melanoma. The successful fusion cells were properly dilute and monoclonal antibody was produced. To monitor the binding activity, a special ELISA was designed to distinguish the binding activities of this bio-nano interaction. For example, I was able to assay for different interactions such as the IgG-gold surface, IgG-physical size, and IgG-shape. In addition, the bio-nano interaction was detected by the single-molecule electrical conductance platform, for a final confirmation.
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Sayes, Christie M. "The bio-nano interface: Examining the interactions between water-soluble nanoparticles and cellular systems." Thesis, 2006. http://hdl.handle.net/1911/18969.

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The cytotoxicity of water-soluble and water-suspendable nanoparticles is a sensitive function of their surface derivatization or surface coating, particle size or specific surface area, and crystalline phase (for nanocrystals). In many different human cell lines, the cytotoxicity of a nanomaterial has been shown to change up to 8 orders of magnitude with relatively minor alterations in its structure. Cellular viability was determined through live/dead staining and LDH release. If the nanomaterial was deemed cytotoxic, further biochemical endpoints were tested. In almost all cases, when the nanoparticles were brought into the aqueous phase reactive species were formed. Ex vivo chemiluminescent analysis qualitatively assessed the presence of RS, and evaluated the effect of choice of solvent, suspension agitation, and light exposure. Liquid atomic force microscopy (AFM) was utilized to examine the interaction of nanomaterials with artificial membranes, illustrating the use of in situ AFM to directly observe the interactions of a model nanoparticle with a model cell membrane. By using in vitro, ex vivo, and in situ techniques, this work demonstrates both a strategy for enhancing the toxicity of nanomaterials for certain applications such as cancer therapeutics or bactericides, as well as a remediation for the possible unwarranted biological effects of nanoparticles.
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Wu, Linxi. "The impact of nanoconjugation to EGF-induced apoptosis." Thesis, 2016. https://hdl.handle.net/2144/14555.

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Engineered nanoparticles provide potential opportunities for improving current drug delivery, bioimaging and biosensing modalities. In many cases, a ligand, such as a protein, peptide or nucleic acids, is attached to the nanoparticles surface to serve as a targeting group. However, the nanoconjugation (i.e. covalently bound molecules to a nanocarrier) is not an innocuous reaction. It can change the binding affinity and interfere with the intracellular trafficking of the tethered species. The understanding of this influence to the tethered species is still lacking. Therefore, the main objective of this thesis is to investigate the effect of nanoconjugation to the biological identity of the tethered biomolecules, in terms of cellular uptake, intracellular trafficking and the ultimate biological outcomes. The Epidermal Growth Factor Receptor (EGFR) is a tyrosine kinase that regulates cell proliferation and can cause cancer if dysregulated. Continuous treatment with high doses of EGF can induce apoptosis, in EGFR overexpressing cell lines. In this thesis, Epidermal Growth Factor (EGF) was chosen as the object of investigation. Covalent attachment of EGF to gold nanoparticles (NP-EGF) was found to enhance apoptosis in EGFR overexpressing cell lines (A431, MDA-MB-468) and it is sufficient to induce apoptosis in cell lines exhibiting EGFR expression at physiological levels (HeLa). NP-EGF accumulation through the endosomal pathway was also investigated to assess the impact of nanoconjugation on the spatio-temporal distribution of NP-EGF as potential origin for the observed enhancement of apoptosis. Two orthogonal experimental approaches were applied: (1) isolation of NP-EGF containing endosomes by taking advantage of the increased density of endosomes associated with the uptake of Au NPs; (2) correlated darkfield/fluorescence imaging to map the spatial distribution of NP-EGF in endosomes as a function of time. The studies reveal that nanoconjugation prolongs the dwelling time of phosphorylated receptors in the early endosomes and that the retention of activated EGFR in the early endosomes is accompanied by an EGF mediated apoptosis at effective concentrations that do not induce apoptosis in the case of the free EGF. Investigating the nanoconjugation-enhanced EGF-induced apoptosis improves the current understanding of cell-nanomatieral interactions and provides new opportunities for overcoming apoptosis evasion by cancer cells.
2017-01-01T00:00:00Z
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Pimenta, Ana Luísa Martins Correia. "Efeito do "Design" de partículas transportadoras de fármacos na seleção da via de internalização celular." Master's thesis, 2013. http://hdl.handle.net/10451/46038.

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Trabalho Final de Mestrado Integrado, Ciências Farmacêuticas, Universidade de Lisboa, Faculdade de Farmácia, 2013
A nanotecnologia emergiu como estratégia promissora na área da saúde, proporcionando uma oportunidade sem precedentes a nível profilático, de diagnóstico e terapêutico de inúmeras patologias. O esforço no co-relacionamento entre as propriedades físico-químicas das nanopartículas transportadoras de fármacos, ou "Nano Drug Delivery Systems", com a resposta biológica é fundamental para a construção de bases racionais que permitam a otimização da formulação, tendo em conta, a finalidade terapêutica pretendida. As nanopartículas com aplicação biomédica têm demonstrado interagir com inúmeras estruturas biológicas de forma intimamente dependente do "design" da partícula que influencia, simultaneamente, o tipo e extensão dessa interação nomeadamente na seleção da via de internalização celular. Assim, para se estabelecer a relevância clínica dos novos nanossistemas terapêuticos, torna-se imperativo a compreensão das interações entre estes e as estruturas biológicas. No entanto, a formulação de partículas transportadoras de fármacos que possuam as propriedades físico-químicas ideais para interagir com o sistema biológico da forma desejada é difícil dada a influência de inúmeros parâmetros condicionantes que conjuntamente determinam o tipo e a extensão dessa interação. Esta monografia apresenta a revisão dos parâmetros críticos de "design" das nanopartículas que influenciam a interação com o sistema biológico, mais concretamente no que respeita à seleção da via de internalização celular.
The nanotechnology emerged as a promising strategy in healthcare, providing an unprecedented opportunity either in a prophylactic level, as a diagnostic or a therapeutic strategy in many diseases. The effort to prove that physicochemical properties of Nano Drug Delivery Systems are related with biological response is crucial to allow the rational optimization of the formulation, taking into account the intended therapeutic purpose. Nanoparticles with biomedical application have shown that nanoparticles interaction with biological structures depends on the system design which influences both, the type and extent of interaction including in select the particular route of cell internalization. Thus, to establish the clinical relevance of new therapeutic nanosystems, it becomes imperative to understand the interactions between the nanomaterial and biological structures. However, the formulation of drug carriers with the suitable physicochemical properties for interacting with the biological system of the desired way is difficult because the influence of several parameters that determine the type and extent this interaction. This work reviews the critical parameters on nanoparticles design that influence the interaction with the biological system, more specifically the selection of internalization pathway.
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Books on the topic "Bio-/nano-interface"

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Arakha, Manoranjan, Arun Kumar Pradhan, and Suman Jha, eds. Bio-Nano Interface. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-2516-9.

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Rahman, Masoud. Protein-Nanoparticle Interactions: The Bio-Nano Interface. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013.

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Laurent, Sophie, Masoud Rahman, and Nancy Tawil. Protein-Nanoparticle Interactions: The Bio-Nano Interface. Springer, 2013.

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Laurent, Sophie, L'Hocine Yahia, Masoud Rahman, Morteza Mahmoudi, and Nancy Tawil. Protein-Nanoparticle Interactions: The Bio-Nano Interface. Springer, 2015.

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Arakha, Manoranjan, Suman Jha, and Arun Kumar Pradhan. Bio-Nano Interface: Applications in Food, Healthcare and Sustainability. Springer Singapore Pte. Limited, 2021.

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Arakha, Manoranjan, Suman Jha, and Arun Kumar Pradhan. Bio-Nano Interface: Applications in Food, Healthcare and Sustainability. Springer, 2022.

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Karak, Niranjan. Dynamics of Advanced Sustainable Nanomaterials and Their Related Nanocomposites at the Bio-Nano Interface. Elsevier, 2019.

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Dynamics of Advanced Sustainable Nanomaterials and their Related Nanocomposites at the Bio-Nano Interface. Elsevier, 2019. http://dx.doi.org/10.1016/c2018-0-01266-9.

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Karak, Niranjan. Dynamics of Advanced Sustainable Nanomaterials and Their Related Nanocomposites at the Bio-Nano Interface. Elsevier Science & Technology Books, 2019.

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Book chapters on the topic "Bio-/nano-interface"

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Biswas, Kunal, Avik Sett, Debashis De, Jaya Bandyopadhyay, and Yugal Kishore Mohanta. "Smart Nanomaterials for Bioimaging Applications: An Overview." In Bio-Nano Interface, 287–306. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_16.

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Preetam, Subham, Lipsa Dash, Suman Sudha Sarangi, Mitali Madhusmita Sahoo, and Arun Kumar Pradhan. "Application of Nanobiosensor in Health Care Sector." In Bio-Nano Interface, 251–70. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_14.

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Mir, Showkat, Nirius Jenan Ekka, Binata Nayak, and Iswar Baitharu. "Bioactive Nanoparticles: A Next Generation Smart Nanomaterials for Pollution Abatement and Ecological Sustainability." In Bio-Nano Interface, 271–85. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_15.

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Das, Bhabani Shankar, Ankita Das, Abhisek Mishra, and Manoranjan Arakha. "Classification, Synthesis and Application of Nanoparticles Against Infectious Diseases." In Bio-Nano Interface, 35–58. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_3.

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Sahu, Jayanta Kumar, Rajendra Kumar Behera, Iswar Baitharu, and Prajna Paramita Naik. "Biology of Earthworm in the World of Nanomaterials: New Room, Challenges, and Future Perspectives." In Bio-Nano Interface, 307–28. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_17.

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Das, Nabojit, and Rayavarapu Raja Gopal. "Impact of Isotropic and Anisotropic Plasmonic Metal Nanoparticles on Healthcare and Food Safety Management." In Bio-Nano Interface, 1–20. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_1.

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Ningthoujam, Rina, Barsarani Jena, Sabita Pattanayak, Santwona Dash, Manasa Kumar Panda, Rajendra Kumar Behera, Nabin Kumar Dhal, and Yengkhom Disco Singh. "Nanotechnology in Food Science." In Bio-Nano Interface, 59–73. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_4.

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Jit, Bimal Prasad, Biswajita Padhan, and Ashok Sharma. "Nanotechnology and Its Potential Implications in Ovary Cancer." In Bio-Nano Interface, 161–75. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_10.

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Mahanta, Sailendra Kumar, and Manoranjan Arakha. "Nanosystems for Cancer Therapy." In Bio-Nano Interface, 127–42. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_8.

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Jena, Sonali, Sonali Mohanty, Monalisha Ojha, Kumari Subham, and Suman Jha. "Nanotechnology: An Emerging Field in Protein Aggregation and Cancer Therapeutics." In Bio-Nano Interface, 177–207. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-2516-9_11.

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Conference papers on the topic "Bio-/nano-interface"

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Yu, X., Linxi Wu, Ali Khanehzar, Amin Feizpour, Fangda Xu, and Björn M. Reinhard. "Probing the nano-bio interface with nanoplasmonic optical probes." In SPIE NanoScience + Engineering, edited by Hooman Mohseni, Massoud H. Agahi, and Manijeh Razeghi. SPIE, 2014. http://dx.doi.org/10.1117/12.2060612.

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Tanguay, Robert L., Lisa Truong, Tatiana Zaikova, and James E. Hutchison. "Rapid In Vivo Assessment of the Nano/Bio Interface." In ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/nemb2013-93153.

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Recent advances in nanoscience offer great promise for the nanomedicine sector. These advances in the nanotechnology field will undoubtedly increase both human and environmental exposures to engineered nanomaterials. Whether these exposures pose a significant risk remains uncertain. Despite recent collective progress there remain gaps in our understanding of the nanomaterials physiochemical properties that drive or dictate biological compatibility. The development and implementation of rapid relevant and efficient testing strategies to assess these emerging materials prior to large-scale exposures could help advance this exciting field. I will present a powerful approach that utilizes a dynamic in vivo zebrafish embryonic assay to rapidly define the biological responses to nanomaterial exposures. Early developmental life stages are often uniquely sensitive to environmental insults, due in part to the enormous changes in cellular differentiation, proliferation and migration required to form the required cell types, tissues and organs. Molecular signaling underlies all of these processes. Most toxic responses result from disruption of proper molecular signaling, thus, early developmental life stages are perhaps the ideal life stage to determine if nanomaterials perturb normal biological pathways. Through automation and rapid throughput approaches, a systematic and iterative strategy has been deployed to help elucidate the nanomaterials properties that drive biological responses.
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Abbott, Jeffrey, Tianyang Ye, Ling Qin, Marsela Jorgolli, Rona Gertner, Donhee Ham, and Hongkun Park. "CMOS-nano-bio interface array for cardiac and neuro technology." In 2017 IEEE International Symposium on Circuits and Systems (ISCAS). IEEE, 2017. http://dx.doi.org/10.1109/iscas.2017.8049752.

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Pakdel, Amir, Takao Mori, Yoshio Bando, and Dmitri Golberg. "Interface engineering of bio-inspired Boron nitride nano-architectures toward controllable hydrophobicity/hydrophilicity." In 2015 IEEE 10th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2015. http://dx.doi.org/10.1109/nems.2015.7147380.

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Hung, S. W., C. P. Chen, and C. C. Chieng. "Ionic Transport in Finite Length Nano-Sized Pores and Channels." In ASME 2008 First International Conference on Micro/Nanoscale Heat Transfer. ASMEDC, 2008. http://dx.doi.org/10.1115/mnht2008-52128.

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Surface-charge regulated ionic transport phenomena in nano-pores and nano-channels have important applications in bio molecular analyses and power conversion involving NEMS. In such devises, the surface-to-volume ratio increases significantly. In nanofluidics, one characteristic is the overlapping of the electrical double layer (EDL) and the disappearance of the electrically neutral zone. The configuration to be considered is a finite length nano pore/channel connected by two reservoirs. Multi-dimensional analyses based on solutions of the Poisson-Nernst-Planck (PNP) equation were performed for the configuration in this study. Numerical solutions show that the ionic transport process in such a configuration depends strongly on the liquid-solid interface models used. These interface models usually serve as wall boundary conditions in multi-dimensional numerical analyses. Most current models were derived based on 1-D fully developed analyses. Issues regarding the extension of the surface chemical equilibrium model to multi-dimensional nanofluidics simulations involving overlapping EDLs were investigated and discussed in this paper.
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Ma, Qisheng, Wenjie Xia, Yongchun Tang, Mohamed Haroun, Md Motiur Rahman, Muhammad Gibrata, Lamia Rouis, et al. "Novel Nano and Bio-Based Surfactant Formulation for Hybrid Enhanced Oil Recovery Technologies." In SPE Annual Technical Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/206288-ms.

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Abstract This investigation presents laboratory and field deployment results that demonstrate the potential candidacy utilizing Nano and bio-technologies to create superior chemicals for novel applications to increase oil recovery from both onshore and offshore reservoirs. Nano-technology is gaining momentum as a tool to improve performance in multiple industries, and has shown significant potential to enhance hydrocarbon production. The laboratory analysis and specifically designed coreflood results indicate there are beneficial interactions at liquid-nano solid interface that increase oil mobility. This will increase the surface activity of chemical surfactants and thereby make them the dominant agents to mobilize and recover oil from oil-bearing reservoirs. Advances in biotechnology offer another rich resource of knowledge for surface active materials that are renewable and more environmental-friendly. In addition, our studies also demonstrate that bio-surfactants are well-suited to provide superior performances in enhancing oil recovery. Nano-particles and biosurfactants may be included with synthetic surfactants to create novel and more efficient surface active agents for enhanced oil recovery. These formulations can promote better flow back of the injected stimulation fluids and additional mobilization to extract more oil from the matrix and micro-fractures. Laboratory experiments demonstrate that the specialized surfactant formulations created, interact with mixed or oil-wet low permeability formations to produce additional oil. Furthermore, this investigation also compares the total production on a candidate field with respect to typical water flood and the novel formulated surfactant approach. For each surfactant treatment, the overall designed injected fluid volume is 1500 m3 (~ 396,000 gallons) with 4 gpt (gallon per thousand unit) of surfactant concentration. Results indicate improved oil production with longer exposure time of the key surfactants within the reservoir. Enhanced surface wetting and super-low interfacial tension (IFT) at lower chemical concentrations are recognized to be the main mechanisms. The novel surfactant also shows stronger sustainability and endurance in keeping rock surface wettability over traditional surfactant system up to 5 times for an 8 PV wash. Furthermore, this can assist to identify and initiate the optimization of the identified mechanisms for potential applications within other compatible reservoirs. A number of successful field applications of EOR with special formulated nano and bio-based surfactant formulation are discussed in this paper. This unique study bridges the gap between the field realized results and lab optimization to enhance feasibility as a function of time and cost.
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Islam, Nazmul, and Davood Askari. "AC Electrothermal Pumping Improvement by Biocompatible Nanocomposite Surface Modification." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-65119.

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The AC electrothermal effect can improve the pumping rate by multiple folds compared to other eletrokinetic techniques in micro/nano scale. In this research, the AC electrothermal micropump velocity will be optimized by surface modification using a biocompatible hydrophobic nanocomposite monolayer. This coating will modify the micropump surface to a hydrophobic surface and reduce the friction losses at the liquid-solid interface, and eventually increase the micropumping velocity. The advent of microfabrication and integrated miniature pumps has applications on biomedical devices such as implantable glucose sensors. These micropumps require the transport of small amounts of fluids (μL range). When utilized in biomedical applications, micropumps can be used to administer small amounts of medication (e.g. insulin) at regular time intervals. These micropumps can also be integrated with the lab-on-a-chip devices and can provide inexpensive disposable devices. To demonstrate the fluid manipulation in high conductive bio-fluids, we have developed an optimized AC electrothermal micropump using symmetrical electrode arrays.
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Siddiqui, Asim, John E. Blume, William C. Manning, Gregory Troiano, Philip Ma, Robert Langer, Vivek Farias, and Omid C. Farokhzad. "Abstract 6571: Plasma protein-protein interactome (PPI) maps derived from the protein corona captured at the nano-bio interface of nanoparticles reveal differential networks for non-small cell lung cancer (NSCLC) and control subjects." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-6571.

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Kim, Sungwon S., Tom T. Huang, Timothy S. Fisher, and Michael R. Ladisch. "Effects of Carbon Nanotube Structure on Protein Adsorption." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-81395.

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Outstanding transport characteristics and high surface-to-volume ratios are several advantages that carbon nanotubes possess that make them attractive candidates for protein immobilization matrices in biosensor applications. A further advantage of using carbon nanotubes is that their structure (e.g., diameter, length, density) can potentially be controlled during synthesis. In the present study, the effects of carbon nanotube structure on enzyme immobilization onto carbon nanotube arrays are investigated. Bovine serum albumin (BSA) serves as both a blocking agent for prevention of nonspecific adsorption and as a support for anchoring bioreceptors. BSA, a globular protein having a 4 to 6 nm characteristic dimension, is stably adsorbed through mechanisms that involve hydrophobic interactions between surfaces presented by the carbon nanotubes and the spacing between the nanotubes with the protein. Protein adsorption is confirmed by fluorescence microscopy of surfaces that have been exposed to fluourescein isothiocyanate (FITC) labeled BSA. The adsorption of biotinylated BSA can be used, through a sandwich immobilization scheme, to provide an anchor for streptavidin, which in turn has at least one other adsorption site that is specific for other biotinylated proteins such as glucose oxidase that would form a biorecognition or catalytic element in a functional biosensor. Correlation between carbon nanotube structure and protein adsorption at the nano-bio interface could eventually lead to growth conditions that yield carbon nanotubes for biosensor applications with optimal protein adsorption characteristics.
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Boldini, Alain, Xinda Ma, John-Ross Rizzo, and Maurizio Porfiri. "A virtual reality interface to test wearable electronic travel aids for the visually impaired." In Nano-, Bio-, Info-Tech Sensors and Wearable Systems, edited by Jaehwan Kim. SPIE, 2021. http://dx.doi.org/10.1117/12.2581441.

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