Relevant bibliographies by topics / Bio-ink

Academic literature on the topic 'Bio-ink'

Author: Grafiati
Published: 14 March 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Contents

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Bio-ink.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Bio-ink"

1

Lee, Su Jeong, Jun Hee Lee, Jisun Park, Wan Doo Kim, and Su A. Park. "Fabrication of 3D Printing Scaffold with Porcine Skin Decellularized Bio-Ink for Soft Tissue Engineering." Materials 13, no. 16 (August 10, 2020): 3522. http://dx.doi.org/10.3390/ma13163522.

Full text
Abstract:
Recently, many research groups have investigated three-dimensional (3D) bioprinting techniques for tissue engineering and regenerative medicine. The bio-ink used in 3D bioprinting is typically a combination of synthetic and natural materials. In this study, we prepared bio-ink containing porcine skin powder (PSP) to determine rheological properties, biocompatibility, and extracellular matrix (ECM) formation in cells in PSP-ink after 3D printing. PSP was extracted without cells by mechanical, enzymatic, and chemical treatments of porcine dermis tissue. Our developed PSP-containing bio-ink showed enhanced printability and biocompatibility. To identify whether the bio-ink was printable, the viscosity of bio-ink and alginate hydrogel was analyzed with different concentration of PSP. As the PSP concentration increased, viscosity also increased. To assess the biocompatibility of the PSP-containing bio-ink, cells mixed with bio-ink printed structures were measured using a live/dead assay and WST-1 assay. Nearly no dead cells were observed in the structure containing 10 mg/mL PSP-ink, indicating that the amounts of PSP-ink used were nontoxic. In conclusion, the proposed skin dermis decellularized bio-ink is a candidate for 3D bioprinting.
APA, Harvard, Vancouver, ISO, and other styles
2

Kim, Ji Seon, Soyoung Hong, and Changmo Hwang. "Bio-ink Materials for 3D Bio-printing." Journal of International Society for Simulation Surgery 3, no. 2 (December 10, 2016): 49–59. http://dx.doi.org/10.18204/jissis.2016.3.2.049.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Jeong, Wonwoo, Min Kyeong Kim, and Hyun-Wook Kang. "Effect of detergent type on the performance of liver decellularized extracellular matrix-based bio-inks." Journal of Tissue Engineering 12 (January 2021): 204173142199709. http://dx.doi.org/10.1177/2041731421997091.

Full text
Abstract:
Decellularized extracellular matrix-based bio-inks (dECM bio-inks) for bioprinting technology have recently gained attention owing to their excellent ability to confer tissue-specific functions and 3D-printing capability. Although decellularization has led to a major advancement in bio-ink development, the effects of detergent type, the most important factor in decellularization, are still unclear. In this study, the effects of various detergent types on bio-ink performance were investigated. Porcine liver-derived dECM bio-inks prepared using widely used detergents, including sodium dodecyl sulfate (SDS), sodium deoxycholate (SDC), Triton X-100 (TX), and TX with ammonium hydroxide (TXA), were characterized in detail. SDS and SDC severely damaged glycosaminoglycan and elastin proteins, TX showed the lowest rate of decellularization, and TXA-based dECM bio-ink possessed the highest ECM content among all bio-inks. Differences in biochemical composition directly affected bio-ink performance, with TXA-dECM bio-ink showing the best performance with respect to gelation kinetics, intermolecular bonding, mechanical properties, and 2D/3D printability. More importantly, cytocompatibility tests using primary mouse hepatocytes also showed that the TXA-dECM bio-ink improved albumin secretion and cytochrome P450 activity by approximately 2.12- and 1.67-fold, respectively, compared with the observed values for other bio-inks. Our results indicate that the detergent type has a great influence on dECM damage and that the higher the dECM content, the better the performance of the bio-ink for 3D bioprinting.
APA, Harvard, Vancouver, ISO, and other styles
4

Han, Jonghyeuk, Wonwoo Jeong, Min-Kyeong Kim, Sang-Hyeon Nam, Eui-Kyun Park, and Hyun-Wook Kang. "Demineralized Dentin Matrix Particle-Based Bio-Ink for Patient-Specific Shaped 3D Dental Tissue Regeneration." Polymers 13, no. 8 (April 15, 2021): 1294. http://dx.doi.org/10.3390/polym13081294.

Full text
Abstract:
Demineralized dentin matrix (DDM)-based materials have been actively developed and are well-known for their excellent performance in dental tissue regeneration. However, DDM-based bio-ink suitable for fabrication of engineered dental tissues that are patient-specific in terms of shape and size, has not yet been developed. In this study, we developed a DDM particle-based bio-ink (DDMp bio-ink) with enhanced three-dimensional (3D) printability. The bio-ink was prepared by mixing DDM particles and a fibrinogen–gelatin mixture homogeneously. The effects of DDMp concentration on the 3D printability of the bio-ink and dental cell compatibility were investigated. As the DDMp concentration increased, the viscosity and shear thinning behavior of the bio-ink improved gradually, which led to the improvement of the ink’s 3D printability. The higher the DDMp content, the better were the printing resolution and stacking ability of the 3D printing. The printable minimum line width of 10% w/v DDMp bio-ink was approximately 252 μm, whereas the fibrinogen–gelatin mixture was approximately 363 μm. The ink’s cytocompatibility test with dental pulp stem cells (DPSCs) exhibited greater than 95% cell viability. In addition, as the DDMp concentration increased, odontogenic differentiation of DPSCs was significantly enhanced. Finally, we demonstrated that cellular constructs with 3D patient-specific shapes and clinically relevant sizes could be fabricated through co-printing of polycaprolactone and DPSC-laden DDMp bio-ink.
APA, Harvard, Vancouver, ISO, and other styles
5

Lee, Su Jeong, Ji Min Seok, Jun Hee Lee, Jaejong Lee, Wan Doo Kim, and Su A. Park. "Three-Dimensional Printable Hydrogel Using a Hyaluronic Acid/Sodium Alginate Bio-Ink." Polymers 13, no. 5 (March 5, 2021): 794. http://dx.doi.org/10.3390/polym13050794.

Full text
Abstract:
Bio-ink properties have been extensively studied for use in the three-dimensional (3D) bio-printing process for tissue engineering applications. In this study, we developed a method to synthesize bio-ink using hyaluronic acid (HA) and sodium alginate (SA) without employing the chemical crosslinking agents of HA to 30% (w/v). Furthermore, we evaluated the properties of the obtained bio-inks to gauge their suitability in bio-printing, primarily focusing on their viscosity, printability, and shrinkage properties. Furthermore, the bio-ink encapsulating the cells (NIH3T3 fibroblast cell line) was characterized using a live/dead assay and WST-1 to assess the biocompatibility. It was inferred from the results that the blended hydrogel was successfully printed for all groups with viscosities of 883 Pa∙s (HA, 0% w/v), 1211 Pa∙s (HA, 10% w/v), and 1525 Pa∙s, (HA, 30% w/v) at a 0.1 s−1 shear rate. Their structures exhibited no significant shrinkage after CaCl2 crosslinking and maintained their integrity during the culture periods. The relative proliferation rate of the encapsulated cells in the HA/SA blended bio-ink was 70% higher than the SA-only bio-ink after the fourth day. These results suggest that the 3D printable HA/SA hydrogel could be used as the bio-ink for tissue engineering applications.
APA, Harvard, Vancouver, ISO, and other styles
6

Sultan, Md Tipu, Ok Joo Lee, Joong Seob Lee, and Chan Hum Park. "Three-Dimensional Digital Light-Processing Bioprinting Using Silk Fibroin-Based Bio-Ink: Recent Advancements in Biomedical Applications." Biomedicines 10, no. 12 (December 12, 2022): 3224. http://dx.doi.org/10.3390/biomedicines10123224.

Full text
Abstract:
Three-dimensional (3D) bioprinting has been developed as a viable method for fabricating functional tissues and organs by precisely spatially arranging biomaterials, cells, and biochemical components in a layer-by-layer fashion. Among the various bioprinting strategies, digital light-processing (DLP) printing has gained enormous attention due to its applications in tissue engineering and biomedical fields. It allows for high spatial resolution and the rapid printing of complex structures. Although bio-ink is a critical aspect of 3D bioprinting, only a few bio-inks have been used for DLP bioprinting in contrast to the number of bio-inks employed for other bioprinters. Recently, silk fibroin (SF), as a natural bio-ink material used for DLP 3D bioprinting, has gained extensive attention with respect to biomedical applications due to its biocompatibility and mechanical properties. This review introduces DLP-based 3D bioprinting, its related technology, and the fabrication process of silk fibroin-based bio-ink. Then, we summarize the applications of DLP 3D bioprinting based on SF-based bio-ink in the tissue engineering and biomedical fields. We also discuss the current limitations and future perspectives of DLP 3D bioprinting using SF-based bio-ink.
APA, Harvard, Vancouver, ISO, and other styles
7

Hsieh, Yi-Chieh, Han-Yi Wang, Kuang-Chih Tso, Chung-Kai Chang, Chi-Shih Chen, Yu-Ting Cheng, and Pu-Wei Wu. "Development of IrO2 bio-ink for ink-jet printing application." Ceramics International 45, no. 13 (September 2019): 16645–50. http://dx.doi.org/10.1016/j.ceramint.2019.05.206.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Neufurth, Meik, Shunfeng Wang, Heinz C. Schröder, Bilal Al-Nawas, Xiaohong Wang, and Werner E. G. Müller. "3D bioprinting of tissue units with mesenchymal stem cells, retaining their proliferative and differentiating potential, in polyphosphate-containing bio-ink." Biofabrication 14, no. 1 (December 31, 2021): 015016. http://dx.doi.org/10.1088/1758-5090/ac3f29.

Full text
Abstract:
Abstract The three-dimensional (3D)-printing processes reach increasing recognition as important fabrication techniques to meet the growing demands in tissue engineering. However, it is imperative to fabricate 3D tissue units, which contain cells that have the property to be regeneratively active. In most bio-inks, a metabolic energy-providing component is missing. Here a formulation of a bio-ink is described, which is enriched with polyphosphate (polyP), a metabolic energy providing physiological polymer. The bio-ink composed of a scaffold (N,O-carboxymethyl chitosan), a hydrogel (alginate) and a cell adhesion matrix (gelatin) as well as polyP substantially increases the viability and the migration propensity of mesenchymal stem cells (MSC). In addition, this ink stimulates not only the growth but also the differentiation of MSC to mineral depositing osteoblasts. Furthermore, the growth/aggregate pattern of MSC changes from isolated cells to globular spheres, if embedded in the polyP bio-ink. The morphogenetic activity of the MSC exposed to polyP in the bio-ink is corroborated by qRT-PCR data, which show a strong induction of the steady-state-expression of alkaline phosphatase, connected with a distinct increase in the expression ratio between RUNX2 and Sox2. We propose that polyP should become an essential component in bio-inks for the printing of cells that retain their regenerative activity.
APA, Harvard, Vancouver, ISO, and other styles
9

Yang, Wei, Anqianyi Tu, Yuchen Ma, Zhanming Li, Jie Xu, Min Lin, Kailong Zhang, et al. "Chitosan and Whey Protein Bio-Inks for 3D and 4D Printing Applications with Particular Focus on Food Industry." Molecules 27, no. 1 (December 28, 2021): 173. http://dx.doi.org/10.3390/molecules27010173.

Full text
Abstract:
The application of chitosan (CS) and whey protein (WP) alone or in combination in 3D/4D printing has been well considered in previous studies. Although several excellent reviews on additive manufacturing discussed the properties and biomedical applications of CS and WP, there is a lack of a systemic review about CS and WP bio-inks for 3D/4D printing applications. Easily modified bio-ink with optimal printability is a key for additive manufacturing. CS, WP, and WP–CS complex hydrogel possess great potential in making bio-ink that can be broadly used for future 3D/4D printing, because CS is a functional polysaccharide with good biodegradability, biocompatibility, non-immunogenicity, and non-carcinogenicity, while CS–WP complex hydrogel has better printability and drug-delivery effectivity than WP hydrogel. The review summarizes the current advances of bio-ink preparation employing CS and/or WP to satisfy the requirements of 3D/4D printing and post-treatment of materials. The applications of CS/WP bio-ink mainly focus on 3D food printing with a few applications in cosmetics. The review also highlights the trends of CS/WP bio-inks as potential candidates in 4D printing. Some promising strategies for developing novel bio-inks based on CS and/or WP are introduced, aiming to provide new insights into the value-added development and commercial CS and WP utilization.
APA, Harvard, Vancouver, ISO, and other styles
10

Habib, Md Ahasan, and Bashir Khoda. "Rheological analysis of bio-ink for 3D bio-printing processes." Journal of Manufacturing Processes 76 (April 2022): 708–18. http://dx.doi.org/10.1016/j.jmapro.2022.02.048.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Bio-ink"

1

Habib, MD Ahasan. "Designing Bio-Ink for Extrusion Based Bio-Printing Process." Diss., North Dakota State University, 2019. https://hdl.handle.net/10365/32045.

Full text
Abstract:
Tissue regeneration using in-vitro scaffold becomes a vital mean to mimic the in-vivo counterpart due to the insufficiency of animal models to predict the applicability of drug and other physiological behavior. Three-dimensional (3D) bio-printing is an emerging technology to reproduce living tissue through controlled allocation of biomaterial and cell. Due to its bio-compatibility, natural hydrogels are commonly considered as the scaffold material in bio-printing process. However, repeatable scaffold structure with good printability and shape fidelity is a challenge with hydrogel material due to weak bonding in polymer chain. Additionally, there are intrinsic limitations for bio-printing of hydrogels due to limited cell proliferation and colonization while cells are immobilized within hydrogels and don’t spread, stretch and migrate to generate new tissue. The goal of this research is to develop a bio-ink suitable for extrusion-based bio-printing process to construct 3D scaffold. In this research, a novel hybrid hydrogel, is designed and systematic quantitative characterization are conducted to validate its printability, shape fidelity and cell viability. The outcomes are measured and quantified which demonstrate the favorable printability and shape fidelity of our proposed material. The research focuses on factors associated with pre-printing, printing and post-printing behavior of bio-ink and their biology. With the proposed hybrid hydrogel, 2 cm tall acellular 3D scaffold is fabricated with proper shape fidelity. Cell viability of the proposed material are tested with multiple cell lines i.e. BxPC3, prostate stem cancer cell, HEK 293, and Porc1 cell and about 90% viability after 15-day incubation have been achieved. The designed hybrid hydrogel demonstrate excellent behavior as bio-ink for bio-printing process which can reproduce scaffold with proper printability, shape fidelity and higher cell survivability. Additionally, the outlined characterization techniques proposed here open-up a novel avenue for quantifiable bio-ink assessment framework in lieu of their qualitative evaluation.
APA, Harvard, Vancouver, ISO, and other styles
2

BARONE, CRISTIANA. "Sox2-dependent molecular functions in the transcriptional controlof glioma and normal neural stem cells." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2021. http://hdl.handle.net/10281/304785.

Full text
Abstract:
Le cellule staminali tumorali (CSC) sono una sottopopolazione di cellule tumorali con caratteristiche di cellule staminali, ovvero autorinnovamento (capacità di riformare un tumore dello stesso tipo) e capacità di "differenziarsi" in cellule che costituiscono la massa tumorale. Questi segni distintivi li rendono responsabili di eventi come recidiva del tumore, metastasi e resistenza ai farmaci. Per questo è molto importante capire quali sono i «fattori» fondamentali per il loro mantenimento. È interessante notare che gli stessi fattori di trascrizione possono essere responsabili del mantenimento sia delle cellule staminali normali che delle cellule staminali tumorali. In particolare sappiamo che il fattore di trascrizione "staminale" Sox2, un importante regolatore delle cellule staminali neurali, è sovraespresso anche nei tumori cerebrali. Nei gliomi, Sox2 è essenziale per mantenere CSC. Nel glioma di alto grado di topo (pHGG), la delezione di Sox2 causa l'arresto della proliferazione cellulare e l'incapacità di riformare i tumori in vivo; 134 geni sono significativamente derepressi. Per identificare i geni che mediano gli effetti della delezione di Sox2, ho overespresso nelle cellule pHGG nove tra i geni più upregolati e ho identificato quattro geni, Cdkn2b, Ebf1, Zfp423 e Hey2, che hanno ridotto fortemente la proliferazione cellulare in vitro e la tumorigenesi cerebrale in vivo. Mediante la mutagenesi CRISPR / Cas9, o inibizione farmacologica, di ciascuno di questi geni, individualmente, ho dimostrato che la loro attività è essenziale per l'arresto della proliferazione causato dalla delezione di Sox2. Questi antioncogeni inibiti da Sox2 hanno anche inibito la clonogenicità in linee di cellule staminali tumorali primarie derivate dal glioblastoma umano. Questi esperimenti identificano fattori anti-oncogenici critici la cui inibizione da parte di Sox2 è coinvolta nel mantenimento della CSC, definendo nuovi potenziali bersagli terapeutici per i gliomi. (Barone et al., 2020; Barone et al., 2018) Oltre a questo lavoro, che costituisce la parte principale del mio lavoro di tesi, ho contribuito a comprendere la funzione di Sox2 nelle cellule staminali neurali normali derivate dal cervello. Qui, studi genome-wide (ChIA-PET; ChIPseq; RNAseq) ci hanno portato a capire che Sox2 agisce nella regolazione genica, a livello genome-wide, mantenendo e regolando una rete genome-wide di interazioni a lungo raggio nella cromatina, collegare promotori genici a stimolatori distanti (Bertolini et al, 2019). Questa nuova prospettiva sulla funzione molecolare di Sox2 ci ha permesso di identificare nuovi geni regolati da Sox2, identificando il legame di SOX2 con esaltatori distanti (ChIPseq), permettendoci di capire quale gene controllano questi potenziatori, attraverso le nostre mappe di interazione a lungo Dati RNAseq). Questo ci ha portato a identificare nuovi importanti mediatori a valle della funzione Sox2 nell'auto-rinnovamento delle cellule staminali neurali (Pagin et al, in corso di revisione).
Cancer Stem Cells (CSCs) are a tumor cell sub-population with stem-cell features, i.e. self- renewal (ability to re-form a tumor of the same type) and the ability to “differentiate” into cells constituting the tumor bulk. These hallmarks make them responsible for events such as tumor relapse, metastasis and drug resistance. For this reason it is very important to understand which are the «factors» fundamental for their maintenance. Interestingly, the same transcription factors may be responsible of the maintenance of both normal stem cells and cancer stem cells. In particular we know that the “stemness” transcription factor Sox2, a major regulator in neural stem cells, is also overexpressed in brain tumors. In gliomas, Sox2 is essential to maintain CSC. In mouse high-grade glioma pHGG, Sox2 deletion causes cell proliferation arrest and inability to reform tumors in vivo; 134 genes are significantly derepressed. To identify genes mediating the effects of Sox2 deletion, I overexpressed into pHGG cells nine among the most derepressed genes, and identified four genes, Cdkn2b, Ebf1, Zfp423 and Hey2, that strongly reduced cell proliferation in vitro and brain tumorigenesis in vivo. By CRISPR/Cas9 mutagenesis, or pharmacological inactivation, of each of these genes, individually, I showed that their activity is essential for the proliferation arrest caused by Sox2 deletion. These Sox2-inhibited antioncogenes also inhibited clonogenicity in primary human glioblastoma-derived cancer stem-like cell lines. These experiments identify critical anti-oncogenic factors whose inhibition by Sox2 is involved in CSC maintenance, defining new potential therapeutic targets for gliomas (Barone et al, Glia, under revision; Barone et al, 2018). Further to this work, constituting the main part of my thesis work, I contributed to understand Sox2 function in normal, brain-derived neural stem cells. Here, genome-wide studies (ChIA- PET; ChIPseq; RNAseq) led us to understand that Sox2 acts in gene regulation, at the genome- wide level, by maintaining and regulating a genome-wide network of long-range interactions in chromatin, connecting gene promoters to distant enhancers (Bertolini et al, 2019). This new perspective on Sox2 molecular function allowed us to identify novel Sox2-regulated genes, by identifying SOX2 binding to distant enhancers (ChIPseq), enabling us to understand which gene these enhancers control, through our long-range interaction maps (ChIA-PET and RNAseq data). This led us to identify important new downstream mediators of Sox2 function in neural stem cell self-renewal (Pagin et al, under revision).
APA, Harvard, Vancouver, ISO, and other styles
3

LAURANO, ROSSELLA. "Stimuli-responsive poly(ether urethane) hydrogels for the design of smart patient-specific patches in skin wound treatment." Doctoral thesis, Politecnico di Torino, 2020. http://hdl.handle.net/11583/2839841.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Hartleb, Carina. "Creation and Evaluation of Solid Optical Tissue Phantoms for Bio-Medical Optics Applications." Thesis, Linköping University, Department of Biomedical Engineering, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-3607.

Full text
Abstract:

Because of their compatibility and precise results bio-optical methods based on measurements of the optical tissue properties gain importance in non-invasive medical therapy and diagnostic. For development and standardization of medical devices optical phantoms are suitable. The present report handles the creation and evaluation of solid tissue phantoms, made up of Agar, Vasolipid and ink utilizing different mixture ratios. After cutting the models in slices of 0.2 to 1.1 mm thickness the absorption- and scattering coefficient were measured using a collimated laser beam setup. As result of the study a formula for the preparation of solid optical tissue phantoms with desired optical properties was found, that is valid for models containing 1.12 % Agar.

APA, Harvard, Vancouver, ISO, and other styles
5

Wun-HongLiang and 梁文紘. "Bio-sample Detection on Paper-based Devices Using Ink-jet Printers." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/08041723150921597977.

Full text
Abstract:
碩士
國立成功大學
工程科學系
102
This study successfully improved the home printer for the spraying of biochemical reagents in paper-based chip production. General biochemistry laboratories use pipettes to introduce the required reagent into paper-based chips. One-piece operation is carried out manually, which is a time-consuming process if the devices are produced in large quantities. The use of automatic production saves time; however, such equipment comes at a high cost. Thus, in order to achieve low-cost mass production, this study attempts to improve the low-cost piezoelectric jet head printer that sprays biochemical reagents into paper-based chips. The following are the advantages of using the printer: low cost, ease of operation, high speed, precise, reproducible and applicable to large scale production. A 2D chip design was employed to simplify the manufacturing process, and the chips were applied to real AST(GOT) and ALT(GPT) testing. The colorimetric method utilizes video equipment to capture images, averages the intensities of the colors and digitizes the information. It then generates a standard curve based on statistical data. The experimental results suggest that the best observation time for AST detection within the 0–105 U/liter concentration range is four min; the linear distribution of the standard curve established based on changes in color is R2 = 0.982. For ALT detection, the optimal observation time within the 0–125 U/liter concentration range is one min, and the linear distribution of the standard curve established based on changes in color is R2 = 0.989. In addition, we demonstrated the detections of AST and ALT were not affected by the impact of glucose concentration Finally, wish the low-cost paper-based chips can be easily applied in personal health care and fast medical diagnosis, allowing the realization of the POC (point of care) concept.
APA, Harvard, Vancouver, ISO, and other styles
6

Chen, Ting-Yueh, and 陳鼎岳. "Feasibility of 3D printable calcium sulfate bio-ink for bone graft substitute applications." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/7vb8e3.

Full text
Abstract:
碩士
臺北醫學大學
醫療器材產業碩士專班
102
Calcium sulfate has been used as one of the absorbable bone substitute materials and is highly biocompatible and osteoconductive. Calcium sulfate based bone grafting material has short setting, and as a result could be used for additive manufacturing technology, such as 3D printing. Calcium sulfate bone cement replacement can be exploited into bio-ink and used for customized bone graft substitute through 3D printing. The proposed research is to be prepared calcium sulfate biological ink and explore the feasibility of alternative bone graft. A set of synthesis and processing techniques based will be developed to prepare the calcium sulfate bio-ink. The prepared bio-ink will be characterized by using material characterization tools including optical microscopy (OM), scanning electron microscopy (SEM), transmission electron microscopy (TEM). Hardness and mechanical properties are determined for further investigation of 3D printing process. Additionally, in order to confirm the biocompatibility for bone graft application, a series of cell experiments will also conducted. These features can be useful in understanding the relationship between the microstructure, physical and mechanical properties of the calcium sulfate bio-ink. The analytical results indicated that the calcium sulfate is a potential 3D printing material that can be applied in biomedical applications.
APA, Harvard, Vancouver, ISO, and other styles

Books on the topic "Bio-ink"

1

Jrock, Ink.: A Concise Report On 40 Of The Biggest Rock Acts In Japan. Stone Bridge Press, 2005.

Find full text
APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Bio-ink"

1

Aravind, Hemand, Blessy Joseph, and Sabu Thomas. "Hydrogel as Bio-Ink for Organ Regeneration." In Gels Horizons: From Science to Smart Materials, 165–79. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-7138-1_9.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Türke, Alexander. "Ink-Jet Printing of Conductive Nanostructures." In Bio and Nano Packaging Techniques for Electron Devices, 293–303. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-28522-6_14.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Barua, Ranjit, Sudipto Datta, Pallab Datta, and Amit Roy Chowdhury. "Scaffolds and Tissue Engineering Applications by 3D Bio-Printing Process." In Design, Development, and Optimization of Bio-Mechatronic Engineering Products, 78–99. IGI Global, 2019. http://dx.doi.org/10.4018/978-1-5225-8235-9.ch004.

Full text
Abstract:
3D bio-printing is a revolutionary manufacturing process that is widely used in medical fields especially in preparing bone scaffolds and tissue engineering. With the help of new biocompatible material like polymers, bio-gels, ceramics, this technology has created a new site in advanced tissue engineering and scaffolds manufacturing area. Another important thing is that, with the use of CAD file software, any complex design can be prepared (i.e., this technology does not have any limited sites). But here it is very much essential to study and analyze machine printability characteristics, cross-linking time and biocompatibility of printing objects as well as bio-ink. However, mechanical properties like shear thinning, mechanical elasticity are also required. In this chapter, different types of scaffold-preparing methods and the bio-printing process are discussed, which are used in scaffold and tissue engineering.
APA, Harvard, Vancouver, ISO, and other styles
4

Barua, Ranjit, Sudipto Datta, Pallab Datta, and Amit Roy Chowdhury. "Scaffolds and Tissue Engineering Applications by 3D Bio-Printing Process." In Research Anthology on Emerging Technologies and Ethical Implications in Human Enhancement, 718–33. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-8050-9.ch037.

Full text
Abstract:
3D bio-printing is a revolutionary manufacturing process that is widely used in medical fields especially in preparing bone scaffolds and tissue engineering. With the help of new biocompatible material like polymers, bio-gels, ceramics, this technology has created a new site in advanced tissue engineering and scaffolds manufacturing area. Another important thing is that, with the use of CAD file software, any complex design can be prepared (i.e., this technology does not have any limited sites). But here it is very much essential to study and analyze machine printability characteristics, cross-linking time and biocompatibility of printing objects as well as bio-ink. However, mechanical properties like shear thinning, mechanical elasticity are also required. In this chapter, different types of scaffold-preparing methods and the bio-printing process are discussed, which are used in scaffold and tissue engineering.
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Bio-ink"

1

Habib, Md Ahasan, and Bashir Khoda. "Effect of Process Parameters on Cellulose Fiber Alignment in Bio-Printing." In ASME 2019 14th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/msec2019-3011.

Full text
Abstract:
Abstract Three dimensional (3D) bio-printing or direct writing technique has become a popular tool in tissue engineering applications that uses a computer-controlled process to deposit bio-ink for reproducing 3D tissue. Among multiple bio-printing modal, extrusion-based printing is capable of depositing diverse range of hydrogel materials and their compositions as bio-ink. Both acellular bio-ink and cell-laden bio-ink can be extruded by controlling the writing parameters to achieve high (>80%) cell survivability and density along with spatial precision and accuracy in 3D space. To increase cell viability and improve mechanical properties, nano-materials are often added in the bio-ink. However, the interplay between 3D bio-printing process parameters, solid fiber content and deposited fiber orientation has not been investigated yet. A novel cellulose based nano-fiber filled bio-ink (i.e. TEMPO nano fibrillated cellulose fiber) is developed and used in this research. The distribution of fiber is explored with respect to the 3D bio-printing process parameters such as nozzle diameter, applied pressure, fiber content and, alginate content. We found, fiber alignments has a very strong correlation with the deposition direction and about 70% fiber falls within 20 degree of the deposition direction.
APA, Harvard, Vancouver, ISO, and other styles
2

Habib, Md Ahasan, and Bashir Khoda. "A Rheological Study of Bio-Ink: Shear Stress and Cell Viability." In ASME 2021 16th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/msec2021-63996.

Full text
Abstract:
Abstract 3D bio-printing is an emerging technology to fabricate tissue scaffold in-vitro through the controlled allocation of biomaterial and cell, which can mimic the in-vivo counterpart of living tissue. Live cells are often encapsulated into the biomaterials (i.e., bio-ink) and extruded by controlling the printing parameters. The functionality of the bioink depends upon three factors: (a) printability, (b) shape fidelity, and (c) bio-compatibility. Increasing viscosity will improve the printability and the shape fidelity; but will require higher applied extrusion pressure, which is detrimental to the living cell dwelling in the bio-ink, which is often ignored in bio-ink optimization process. In this paper, we demonstrate a roadmap to develop and characterize bio-inks ensuring the printability, shape fidelity, and cell survivability, simultaneously. The pressure exerted on the bio-ink during extrusion processes is measured analytically and the information is incorporated in the rheology design of the bio-ink. Cell-laden filament is fabricated with Human Embryonic Kidney (HEK 293) cell and analyzed the cell viability. The overall cell viability of the filament fabricated with 8 psi and 12 psi is 90% and 74% respectively. Additionally, a crossectional live-dead assay of the printed filament with HEK 293 cell is performed which demonstrates the spatial pattern that matches our findings as well.
APA, Harvard, Vancouver, ISO, and other styles
3

Habib, Ahasan, and Bashir Khoda. "Fiber Filled Hybrid Hydrogel for Bio-Manufacturing." In ASME 2020 15th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/msec2020-8294.

Full text
Abstract:
Abstract The extrusion based three-dimensional (3D) bio-printing deposits cell-laden bio-ink with high spatial resolution and may offer living tissue regeneration. Due to the biocompatibility, less cytotoxicity and high water content, natural hydrogels are commonly considered as the bio-ink for scaffold fabrication. However, due to the low mechanical integrity, a large scale scaffold (> 10 layers) with intricate architecture is a challenge. In this paper, Cellulose-based nano-fiber and CMC are added with alginate material to improve the rheological behavior of the hybrid hydrogel. Shear-thinning behavior, shape fidelity, printability of the composition are investigated and evaluated for various compositions. Finally, both regular and freeform 3D scaffolds are fabricated with the proposed hybrid hydrogel to validate its printability and shape fidelity. The required properties of bio-ink are highly dependent upon the percentage composition and the solid content.
APA, Harvard, Vancouver, ISO, and other styles
4

Kharel, Prabhuti, Rahmatul Mahmoud, and Kunal Mitra. "RHEOLOGICAL ANALYSIS OF CELL EMBEDDED HYDROGEL BIO-INK FOR EXTRUSION BIOPRINTING." In 3rd Thermal and Fluids Engineering Conference (TFEC). Connecticut: Begellhouse, 2018. http://dx.doi.org/10.1615/tfec2018.rhe.021751.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Matsuura, Koji, Ikuyo Sugimoto, Mieko Kodama, and Masayuki Kanehara. "Electrode fabrication using conductive nano-ink and microfluidic technology for bio-applications." In 2012 International Symposium on Micro-NanoMechatronics and Human Science (MHS). IEEE, 2012. http://dx.doi.org/10.1109/mhs.2012.6492397.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

D, Subitha, Rahul S. G, Velmurugan S, and Salveru Saiteja. "Curing Free, Silver Nano Ink Based Inkjet Printed Fabrics for Bio-Medical Applications." In 2022 IEEE International Conference on Nanoelectronics, Nanophotonics, Nanomaterials, Nanobioscience & Nanotechnology (5NANO). IEEE, 2022. http://dx.doi.org/10.1109/5nano53044.2022.9828925.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Nelson, Cartwright, Slesha Tuladhar, and Md Ahasan Habib. "Designing an Interchangeable Multi-Material Nozzle System for 3D Bioprinting Process." In ASME 2021 16th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/msec2021-63471.

Full text
Abstract:
Abstract Three-dimensional bioprinting is a rapidly growing field attempting to recreate functional tissues for medical and pharmaceutical purposes. Development of functional tissue requires deposition of multiple biomaterials encapsulating multiple cell types i.e. bio-ink necessitating switching ability between bio-inks. Existing systems use more than one print head to achieve this complex interchangeable deposition, which decreases efficiency, structural integrity, and accuracy. In this research, we developed a nozzle system capable of switching between multiple bio-inks with continuous deposition ensuring the minimum transition distance so that precise deposition transitioning can be achieved. Finally, the effect of rheological properties of different bio-material compositions on the transition distance is investigated by fabricating the sample scaffolds.
APA, Harvard, Vancouver, ISO, and other styles
8

Lai, Wei-Cheng, Kathryn Moncivais, Swapnajit Chakravarty, Xiaolong Wang, Che-Yun Lin, Zhiwen J. Zhang, and Ray T. Chen. "High Density Ink Jet Printing of Bio-molecules for Photonic Crystal-based Microarray Applications." In Optical Sensors. Washington, D.C.: OSA, 2011. http://dx.doi.org/10.1364/sensors.2011.swa4.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Nasir, Abdul, Yuya Mikami, Taku Takagishi, Rui Yatabe, Hiroaki Yoshioka, Nilesh J. Vasa, and Yuji Oki. "Fully room temperature bio-sensing using active microdisk fabricated by ink-jet printing method." In CLEO: Applications and Technology. Washington, D.C.: OSA, 2020. http://dx.doi.org/10.1364/cleo_at.2020.aw3k.5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Ding, Houzhu, and Robert C. Chang. "Bioprinting of Liquid Hydrogel Precursors in a Support Bath by Analyzing Two Key Features: Cell Distribution and Shape Fidelity." In ASME 2018 13th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/msec2018-6675.

Full text
Abstract:
Microextrusion-based bioprinting within a support bath material is an emerging additive manufacturing technique for fabricating complex three-dimensional (3D) tissue constructs. However, there exists fundamental knowledge gaps in understanding the spatiotemporal mapping of cells within the bioprinted constructs and their shape fidelity when embedded in a support bath material. To address these questions, this paper advances quantitative analyses to systematically determine the spatial distribution for cell-laden filament-based tissue constructs as a function of the bio-ink properties. Also, optimal bio-ink formulations are investigated to fabricate complex 3D structures with superior shape integrity. Specifically, for a 1D filament printed in a support bath, cells suspended in low viscosity liquid hydrogel precursors are found to exhibit a characteristic non-uniform distribution as measured by a degree of separation (Ds) metric. In a 2D square wave pattern print, cells are observed to flow and aggregate downstream at certain positions along the in-plane print direction. In a 3D analysis, owing to the high cell density and gravity effects, a non-uniform cell distribution within a printed cylindrical structure is observed in the build direction. From the structural standpoint, the addition of CaCl2 to the support bath activates the hydrogel cross-linking process during printing, resulting in 3D prints with enhanced structural outcomes. This multidimensional print analysis provides evidence that, under the emerging bioprinting support bath paradigm, the printable parameter space can be extended to low viscosity liquid hydrogel precursor materials that can be systematically characterized and optimized for key process performance outcomes in cell distribution and shape fidelity.
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Bio-ink' for particular source types:
Journal articles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography