Academic literature on the topic 'Bio-Impression 3D'
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Journal articles on the topic "Bio-Impression 3D"
Ramilison, Eloi, Axel Legouge, Michel Lucciano, Catherine Masson, and Arnaud Deveze. "Caractérisation acoustique de conduits auditifs externes normaux : de l’humain aux modèles imprimés 3D." Audiology Direct, no. 4 (2020): 5. http://dx.doi.org/10.1051/audiodir/202004005.
Full textTravassos, Rosana Maria Coelho, Renata Wiertz Cordeiro, Nathanny Christinne Garrido de Macedo Santiago Guedes de Oliveira, William Wale Rodrigues Martins, Pedro Guimarães Sampaio Trajano dos Santos, Luciana Oliveira Leal, Cecília Alves Leopoldino, and Viviane Ferreira Guimarães Xavier. "Endodontic guide for the conservative removal of a fiber-reinforced composite resin post: A Dental Technique." Derecho y Cambio Social 21, no. 78 (January 3, 2025): e53. https://doi.org/10.54899/dcs.v21i78.53.
Full textDESSAUGE, Frédéric, Cindy SCHLEDER, Marie-Héléne PERRUCHOT, and Karl ROUGER. "Développement des modèles de culture cellulaire de muscle en 3D : de nouvelles opportunités pour les productions animales." INRAE Productions Animales 36, no. 2 (September 13, 2023). http://dx.doi.org/10.20870/productions-animales.2023.36.2.7626.
Full textPeeney, David. "Assessing the effects of TIMP2 knockout on lung cancer cell lines cultured in 3D." FASEB Journal 31, S1 (April 2017). http://dx.doi.org/10.1096/fasebj.31.1_supplement.808.4.
Full textDissertations / Theses on the topic "Bio-Impression 3D"
Poerio, Aurelia. "Élaboration par bio-impression 3D et caractérisation de biomatériaux naturels pour l'ingénierie tissulaire." Electronic Thesis or Diss., Université de Lorraine, 2021. http://www.theses.fr/2021LORR0256.
Full text3D bioprinting is a tissue engineering technology based on the combination of biomaterials, cells and bioactive molecules for the fabrication of tissue substitutes able to restore, replace and/or repair the damaged ones. Biomaterials act as a temporary extracellular matrix and promote the migration, proliferation and differentiation of cells. This ability is either due to biomaterial's intrinsic properties or to their modification through the inclusion of biochemical cues, such as growth factors. The objective of this thesis is to develop new biomaterials allowing 3D printing and new strategies allowing for their application in tissue engineering, using, in particular, the technology of 3D bioprinting. In order to do that, we firstly extracted chitin from an unusual source, cicadas sloughs, and transformed it into its derivative chitosan. These two polysaccharides were characterized from a physicochemical point of view. Furthermore, for the first time to our knowledge, we also characterized the raw material (i.e., cicada sloughs) and the intermediary products of the extraction process, which proved important to evaluate the stability of cicada sloughs as a source of chitin. Chitosan, a derivative of chitin, was then used to develop new biomaterial inks for extrusion 3D printing through its combination with two natural gums: guar gum and tamarind gum. These are polysaccharides derived from seed plants and widely used as thickening and gelling agents by the food industries. Their addition to chitosan improved its printability and, through a dual gelation mechanism, led to the fabrication of stable 3D constructs with improved mechanical properties. Subsequently, after reviewing the 3D bioprinting strategies used to control the release of growth factors from 3D printed and bioprinted constructs, PLGA microspheres were included into a 3D bioprinted skeletal muscle construct as neurotrophic factors delivery system in order to improve and accelerate the innervation of the developed scaffold
Blyweert, Pauline. "Carbones fonctionnels architecturés par impression 3D de résines biosourcées." Electronic Thesis or Diss., Université de Lorraine, 2023. http://www.theses.fr/2023LORR0132.
Full textIn this thesis, porous carbon architectures obtained by pyrolysis of stereolithography (SLA)-printed biosourced photosensitive resins derived from tannin and organic acrylate binder were prepared to study their properties. The textural and mechanical properties of the porous carbons were adapted by modifying the precursor resin formulations in terms of tannin quantity, acrylate resin binder composition or the type of biosourced precursor used. These different approaches have led to the production of a wide range of carbon structures whose properties can easily be adjusted for environmental or electromagnetic applications. Thus, after physical activation, 3D-printed carbon monoliths applied to heterogeneous catalysis in the liquid phase for water treatment, and in the gas phase for CO2 valorization, have shown promising performances. In addition, thanks to their moderate electrical conductivity, carbons and carbon-dielectric material or carbon-ferromagnetic material composites obtained by SLA are potential alternative to conventional methods to produce broadband absorbers metasurfaces and metamaterials for electromagnetic shielding at high frequencies (between 8 and 40 GHz). Finally, the multiphysics modeling of the two main processes to obtain carbon architecture, printing and then pyrolysis, has also led to a better understanding of the interactions of the physical phenomena involved during these stages. More than a prediction tool, the numerical approach becomes a process and material optimization tool
Fournie, Victor. "Développement d’une bio-imprimante 3D opto-fluidique pour l’impression haute résolution et multimatériaux d’hydrogel." Electronic Thesis or Diss., Toulouse, INSA, 2023. http://www.theses.fr/2023ISAT0057.
Full textIn this thesis report, we introduce a pioneering concept in 3D printing applied to biological applications. The 3D-FlowPrint platform has been devised to execute high-resolution prints using multiple materials. This approach addresses the current limitations inherent in existing technologies. Micro-extrusion, stereolithography, and microfluidic probes possess individual capabilities to handle heterogeneous objects printing, achieve high resolutions, and manipulate fluids with precision. However, these capabilities have never been fully united in a proper technic. The 3D-FlowPrint platform draws inspiration from each of these concepts. It employs a microfluidic system to channel fluids to a submerged printhead, where the injected solution undergoes photopolymerization. By decoupling material deposition from polymerization, this platform attains both high resolution and the versatility to work with diverse materials.The heart of this platform resides in the design of its printhead. This printhead enables fluid injection and retrieval without environmental contamination, while facilitating laser transmission through an integrated optical fiber. To achieve these goals, we have developed four successive generations of printheads. The first generation, machined and molded, demonstrated the feasibility of the concept but presented room for improvement. The second generation, entirely 3D printed, introduced new geometric possibilities and rapid prototyping but faced challenges with optical interfaces. The third generation combined 3D printing with optically compatible material assembling. It enabled reproducible PEGDA prints to develop and characterize the platform, yet it encountered limitations for GelMA printing. The fourth generation overcame this challenge by introducing an air bubble under the printhead, resolving third-generation issues.This manuscript also analyzes the microfluidic system. The printheads operate immersed, enabling printing in cultured environments. These heads include an injection channel and an aspiration channel, along with surface reliefs ensuring complete collection of the injected solution to minimize contamination. Utilizing finite element-based numerical simulations, phase diagrams have been established to evaluate the material collection capacity. These simulations guided the optimization of surface reliefs to enhance the performance of the printheads. Additionally, the ability to transition from one fluid to another in multi-material printing was analyzed.The introduction of an optical fiber between the microfluidic channels allowed the photopolymerization of the injected solution. The platform gained versatility with dual printing speeds enabled by the insertion of two optical fibers in the 3D printed printheads. Photopolymerization thresholds of PEGDA and GelMA were investigated, and the impact of in-flow photopolymerization was verified. These analyses culminated in the printing of 2D, 2.5D, 3D, and multi-material structures with reproducible precision down to 7 micrometers.Serving as proof of concept for biological applications, the platform was employed in four distinct approaches. First, PEGDA objects prevented cell adhesion on specific part of the substrate, enabling the study of geometrically constrained development. Second, scaffold structures for surfacic 3D tissues were printed. Third, the printing of suspension of cells in GelMA was achieved, along with the characterization of cellular viability using this method. Lastly, a hybrid platform was developed for co-printing hydrogels and positioning 3D spheroids
Mei, Zhenying. "Valorisation des insectes comme source alternative de chitine et de chitosane pour les applications d'élimination des polluants et la bio-impression 3D." Electronic Thesis or Diss., Université Côte d'Azur, 2024. https://theses.hal.science/tel-04885373.
Full textChitin and chitosan have considerable potential for a number of applications in a variety of fields, including biotechnology, engineering, agriculture, the food industry, environmental sciences and so on, due to their distinctive properties and adaptability. Chitin is a linear polysaccharide composed of β-(1-4)-linked N-acetylglucosamine (GlcNAc) units. Chitosan is obtained by the partial deacetylation of chitin via removal of the acetyl groups from the GlcNAc units. The degree of deacetylation determines the extent of conversion from chitin to chitosan and impacts its physicochemical properties. Chitin and chitosan are derived mainly from seafood wastes (shrimps, lobsters, crabs, etc.). However, this resource is unable to support the growing needs and future projections for chitin and chitosan. The global chitin market size is set to be valued at around US dollars 1,801.3 million in 2023 and is anticipated to reach US dollars 5,746.2 million by 2033. Global demand for chitosan continues to rise at an annual rate of 15.4%. There is a pressing need for alternative and sustainable sources of chitin and chitosan to overcome limitations associated with conventional sources, and to investigate novel materials with enhanced properties. Hence, insects may be considered as an abundant and sustainable source of chitin and chitosan. Insects have rapid reproduction rates, short lifecycles, and require minimal resources for breeding, ensuring a consistent available supply of chitin and chitosan.This thesis provides a comprehensive review on the current state of insect-derived chitin and chitosan, focusing on their sources, production methods, characterization, physical and chemical properties, and various applications. Then, we investigated 11 different insect species as a starting material for chitin extraction and chitosan preparation. These include nine species belonging to Curculionidae family, Heteronitis castelnaui belonging to Scarabaeidae family, and Eurycantha calcarata belonging to Lonchodidae family. All the obtained chitin and chitosan was thoroughly characterized using various analytical techniques such as Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), nuclear magnetic resonance (NMR), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). Then the obtained Heteronitis castelnaui chitosan and Eurycantha calcarata chitosan were further investigated for the applications. Heteronitis castelnaui chitosan demonstrated excellent performance in the formation of hydrogels and exhibited remarkable adsorption capacity for methylene blue and methyl orange. Eurycantha calcarata chitosan-based hydrogel exhibited favorable 3D printability characteristics, high biocompatibility and non-toxic nature. These preliminary data confirm that these studied species may be considered as potential source of chitin and chitosan for industrial uses
Thibaut, Camille. "Développement de matériaux fibreux cellulosiques pour la production d'objets bio-sourcés imprimés en 3D par extrusion." Thesis, Université Grenoble Alpes, 2020. https://tel.archives-ouvertes.fr/tel-02570560.
Full textThis project aims at developing new cellulosic bio-based materials for additive manufacturing (AM) by extrusion to produce complex and multi-materials 3D parts. First, this project has evaluated the compatibility of aqueous and high solid content formulations with AM by extrusion. Formulations composed of micrometric organics fillers (cellulose fibers or powder and graphite powder) and cellulose derivatives (carboxymethyl cellulose) were investigated and results in a selection of homogeneous pastes with strong potential for AM by extrusion and limited deformation of the printed part upon air drying. The second stage of this project focused on adjustment and optimization of AM by extrusion equipment and the related settings to guarantee an optimum shape accuracy of 3D printed parts compared to the 3D numerical model. A printing setting guideline and design limitations adapted to the developed paste were suggested. To characterize the printing parts, different innovative methods such as the temporal monitoring by X-ray tomography of a printed part upon drying were implemented. The results of this project lead to the AM by extrusion of complex part 100% cellulose based with mechanical properties close to thermoplastic materials commonly used with fused filament fabrication process
Dourgaparsad, Kevin. "Superhydrophobic bio-inspired microarchitectured stainless steel surfaces." Electronic Thesis or Diss., Université de Lille (2022-....), 2024. https://pepite-depot.univ-lille.fr/ToutIDP/EDSMRE/2024/2024ULILR009.pdf.
Full textSuperhydrophobic surfaces have low water wetting due to their chemical nature and/or surface state structured at multiple scales (micro and nano). Additive manufacturing (AM) processes using stainless steel are expensive due to the cost of stainless steel powder. Additionally, the precision of these technologies rarely goes below 200 μm. The presented work combines two technologies, namely polymer 3D printing and vacuum casting (lost-wax casting), to create various bio-inspired microtextured surfaces in 316L stainless steel from stainless steel waste. Casting micrometric details in stainless steel foundry is a technical challenge due to high surface tension, high dynamic viscosity, and high working temperature (1600°C). Various bioinspired microtextured surfaces (fish scales, drops, honeycomb, etc.) have been successfully manufactured. A nanoscale coating was then applied through atmospheric pressure plasma polymerization to nanotexture the surface, leading to an ultrahydrophobic behavior. Finally, various potential applications for these surfaces, such as anti-fouling, anti-icing, or impregnation with vegetable oil for the development of slippery liquid-infused porous surfaces (SLIPS), are explored and discussed
Danché, Valentine. "Impression 3D par liaison sélective de béton de chanvre." Electronic Thesis or Diss., CY Cergy Paris Université, 2024. http://www.theses.fr/2024CYUN1286.
Full text3D printing is experiencing a significant rise in the construction industry, paving the way for the expected digitalization of the sector. As new techniques are explored to combine technical optimization and CO2 emission reduction, this study focuses on powder-bed 3D printing. Despite still being relatively niche, this method could facilitate printing with a high natural fiber content, thus taking a further step towards carbon neutrality. The process is simple, involving three iterative steps : depositing a layer of reactive powder, compacting it, and then injecting water onto the surface.Hence, controlling water penetration into the powder is crucial to improve print quality. The objective is to confine the available water to the desired area, ensuring optimal binder hydration and preventing leaching from previous layers. Several factors may limit penetration depth, including the physical properties of the powder (compactness, permeability) and those of the injected fluid (surface tension, viscosity, yield stress) to study their impact on the kinetics of water propagation on the surface and within the powder. Consequently, we examined the vertical water propagation kinetics in compacted cementitious powder samples. To better simulate the phenomena occurring within the printer, vertical imbibition in both penetration directions was monitored through image analysis and MRI, providing additional insights into the quantity and distribution of water in the samples.Following the development of a versatile setup, we investigated pure powders (such as cement, calcite, metakaolin, sand) and those containing porous aggregates (recycled cement paste or micronized hemp shives) to better understand their impact on water penetration in a bio-sourced printable powder. Indeed, this technique sheds new light with a saturation sensibility and, when combined with MRI, water transfers between the matrix and porous aggregates. Natural porous aggregates like hemp are well-known to affect water distribution as they absorb and swell on contact with water. The results indicate that kinetics do not always slow down over time which opens discussions on the validity of Washburn's Law, commonly used to describe water propagation phenomena in porous media.Finally, the complete development of a powder-bed 3D printer has enabled the printing of cubes, which will facilitate the study of the influence of printing parameter choices (injection type and compactness) on part geometry. We will then be able to consider biobased materials as a possible tool for improving printing precision
Baka, Zakaria. "Élaboration de cancers sur puce pour des applications en thérapies anticancéreuses." Electronic Thesis or Diss., Université de Lorraine, 2023. http://www.theses.fr/2023LORR0175.
Full textOvarian cancer is a major public health issue. Moreover, new treatments still face very high failure rates. This is mainly due to the unreliability of conventional preclinical models such as 2D cell culture. Thus, new tools based on 3D cell culture have emerged such as spheroids and organoids. However, these models have their own limitations (cost, difficulty of application). 3D bioprinting is a new approach to create tunable and reproducible tumor models. However, very few bioprinted tumor models have been reported so far. Besides the “third dimension”, it is important to consider the dynamic conditions of the tumor environment. This has been possible for some years now thanks to microfluidics-based cancer-on-a-chip technology. However, this technology currently does not simulate the drug vascular transport before its interaction with the tumor cells. In this PhD project, we set out to create a dynamic, three-dimensional model of ovarian cancer by combining 3D bioprinting and microfluidics. First, 3D bioprinting was used to create the tumor structure itself. For that, we formulated a bio-ink comprising SKOV-3 ovarian cancer cells and MeWo cancer fibroblasts embedded in a gelatin – alginate hydrogel. The bioprinted tumor structures were then characterized by various techniques to demonstrate their viability and biological relevance. Their response to anticancer drug cisplatin was also assessed. In the second step, we integrated the bioprinted tumor model into a microfluidic support for culture under physiological flow. This support was also intended to simulate the drug's vascular transport prior to interaction with the tumor tissue. We then used computational fluid dynamics to design an improved version of the first system. The aim of this improved version was to simultaneously assess multiple drug concentrations. This PhD project demonstrated the ability of 3D bioprinting to create viable and functional ovarian tumor models. It has also brought interesting research prospects with regard to the possibilities of combining 3D bioprinting and microfluidics to improve preclinical modeling of ovarian tumors
Conference papers on the topic "Bio-Impression 3D"
Catros, S. "A quoi servent les Bio-Imprimantes 3D ?" In 66ème Congrès de la SFCO. Les Ulis, France: EDP Sciences, 2020. http://dx.doi.org/10.1051/sfco/20206601012.
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