Relevant bibliographies by topics / Benzolactum

Contents

  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Benzolactum'

Author: Grafiati
Published: 6 September 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Benzolactum.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Benzolactum"

1

Lam, Hon-Wah, Ka-Yi Man, Wai-Wing Chan, Zhongyuan Zhou, and Wing-Yiu Yu. "Rhodium(iii)-catalyzed formal oxidative [4 + 1] cycloaddition of benzohydroxamic acids and α-diazoesters. A facile synthesis of functionalized benzolactams." Org. Biomol. Chem. 12, no. 24 (2014): 4112–16. http://dx.doi.org/10.1039/c4ob00512k.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

DeVita, R. J., and M. J. Wyvratt. "Benzolactam growth hormone secretagogues." Drugs of the Future 21, no. 3 (1996): 273. http://dx.doi.org/10.1358/dof.1996.021.03.353289.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Ryu, Ilhyong, Takahide Fukuyama, and Takanobu Bando. "Electron-Transfer-Induced Intramolecular Heck Carbonylation Reactions Leading to Benzolactones and Benzolactams." Synthesis 50, no. 15 (May 29, 2018): 3015–21. http://dx.doi.org/10.1055/s-0037-1609964.

Full text
Abstract:
A metal-catalyst-free intramolecular Heck carbonylation reaction of benzyl alcohols and benzyl amines with carbon monoxide under heating at 250 °C affords the corresponding benzolactones and benzolactams in good to excellent yields. A hybrid radical/ionic chain mechanism, involving electron transfer from radical anions generated by nucleophilic attack of alcohols or amines on intermediate acyl radicals, is proposed.
APA, Harvard, Vancouver, ISO, and other styles
4

Bouillon, J. P., C. Atès, C. Maliverney, Z. Janousek, and H. G. Viehe. "β-TRIFLUOROACETYLATION OF LACTAMS AND BENZOLACTAMS." Organic Preparations and Procedures International 26, no. 2 (April 1994): 249–55. http://dx.doi.org/10.1080/00304949409458029.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Khantikaew, Itsara, Masato Takahashi, Takuya Kumamoto, Noriyuki Suzuki, and Tsutomu Ishikawa. "Synthesis of (−)-benzolactam-V8 by application of asymmetric aziridination." Tetrahedron 68, no. 3 (January 2012): 878–82. http://dx.doi.org/10.1016/j.tet.2011.11.033.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Bock, Mark G., Robert M. DiPardo, Daniel F. Veber, Raymond S. L. Chang, Victor J. Lotti, Stephen B. Freedman, and Roger M. Freidinger. "Benzolactams as non-peptide cholecystokinin receptor ligands." Bioorganic & Medicinal Chemistry Letters 3, no. 5 (May 1993): 871–74. http://dx.doi.org/10.1016/s0960-894x(00)80683-6.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Ma, Dawei, Guoqiang Wang, Shaomeng Wang, Alan P. Kozikowski, Nancy E. Lewin, and Peter M. Blumberg. "Synthesis and protein kinase C binding activity of benzolactam-V7." Bioorganic & Medicinal Chemistry Letters 9, no. 10 (May 1999): 1371–74. http://dx.doi.org/10.1016/s0960-894x(99)00207-3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Mokrosz, Maria J., Sijka Charakchieva-Minol, and Piotr Kowalski. "Benzolactam Derivatives and Their Affinity for α1- and α2- Adrenoreceptors." Archiv der Pharmazie 334, no. 1 (January 2001): 25–26. http://dx.doi.org/10.1002/1521-4184(200101)334:1<25::aid-ardp25>3.0.co;2-8.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

De Vita, Robert J., Alison J. Frontier, William R. Schoen, Matthew J. Wyvratt, Michael H. Fisher, Kang Cheng, Wanda W. S. Chan, Bridget S. Butler, and Roy G. Smith. "Design and Synthesis of Potent Macrocyclic Benzolactam Growth Hormone Secretagogues." Helvetica Chimica Acta 80, no. 4 (June 30, 1997): 1244–59. http://dx.doi.org/10.1002/hlca.19970800421.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Bouillon, Jean-Philippe, Célâl Ates, Zdenek Janousek, and Heinz G. Viehe. "Trifluoromethylated heterocycles from β-trifluoroacetyl-lactams and -benzolactams." Tetrahedron Letters 34, no. 32 (August 1993): 5075–78. http://dx.doi.org/10.1016/s0040-4039(00)60679-2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Benzolactum"

1

López, Muñoz Laura. "Homology modeling and structural analysis of the antipsychotic drugs receptorome." Doctoral thesis, Universitat Pompeu Fabra, 2010. http://hdl.handle.net/10803/7228.

Full text
Abstract:
Classically it was assumed that the compounds with therapeutic effect exert their action interacting with a single receptor. Nowadays it is widely recognized that the pharmacological effect of most drugs is more complex and involves a set of receptors, some associated to their positive effects and some others to the side effects and toxicity. Antipsychotic drugs are an example of effective compounds characterized by a complex pharmacological profile binding to several receptors (mainly G protein-coupled-receptors, GPCR). In this work we will present a detailed study of known antipsychotic drugs and the receptors potentially involved in their binding profile, in order to understand the molecular mechanisms of the antipsychotic pharmacologic effects.

The study started with obtaining homology models for all the receptors putatively involved in the antipsychotic drugs receptorome, suitable for building consistent drug-receptor complexes. These complexes were structurally analyzed and compared using multivariate statistical methods, which in turn allowed the identification of the relationship between the pharmacological properties of the antipsychotic drugs and the structural differences in the receptor targets. The results can be exploited for the design of safer and more effective antipsychotic drugs with an optimum binding profile.
Tradicionalmente se asumía que los fármacos terapéuticamente efectivos actuaban interaccionando con un único receptor. Actualmente está ampliamente reconocido que el efecto farmacológico de la mayoría de los fármacos es más complejo y abarca a un conjunto de receptores, algunos asociados a los efectos terapéuticos y otros a los secundarios y toxicidad. Los fármacos antipsicóticos son un ejemplo de compuestos eficaces que se caracterizan por unirse a varios receptores simultáneamente (principalmente a receptores unidos a proteína G, GPCR). El trabajo de la presente tesis se ha centrado en el estudio de los mecanismos moleculares que determinan el perfil de afinidad de unión por múltiples receptores de los fármacos antipsicóticos.

En primer lugar se construyeron modelos de homología para todos los receptores potencialmente implicados en la actividad farmacológica de dichos fármacos, usando una metodología adecuada para construir complejos fármaco-receptor consistentes. La estructura de estos complejos fue analizada y se llevó a cabo una comparación mediante métodos estadísticos multivariantes, que permitió la identificación de asociaciones entre la actividad farmacológica de los fármacos antipsicóticos y diferencias estructurales de los receptores diana. Los resultados obtenidos tienen interés para ser explotados en el diseño de fármacos antipsicóticos con un perfil farmacológico óptimo, más seguros y eficaces.
APA, Harvard, Vancouver, ISO, and other styles
2

Sherikar, Mahadev. "Construction of C-C bonds by C-H Activation: Rh(III)-Catalyzed reactions of Arenes and Heteroarenes with Maleimides and Allylic Alcohols." Thesis, 2021. https://etd.iisc.ac.in/handle/2005/5227.

Full text
Abstract:
The thesis presents a few Rh-catalyzed C-H activations for the construction of C-C bonds. The difficulty of substitution or the arylation at the maleimide's double bond under C-H activation conditions prompted a detailed study on the reaction of maleimides with 3-trifluoromethyl ketone of indole. In this study, it was realized that switching the reactions between the Heck-type reaction and hydroarylation can be achieved by using basic or acid additives. A weakly coordinating carboxylate directing group assisted C-H activation with maleimides leading to a novel and switchable decarboxylative Heck-type and [4+1] annulation products catalyzed by Rh(III)-catalyst is investigated. In these reactions, solvents play a vital role in switching the selectivity. An aprotic solvent, THF, leads to the decarboxylative Heck-type product while the protic solvent, TFE, paves [4+1] annulation product. Allyl alcohol is chemically equivalent to α,β-unsaturated ketones, and aldehydes. A weakly coordinating carbonyl-directed coupling of allyl alcohols at the C-4 position of indole derivatives under the C-H activation conditions using an Rh(III)-catalyst has been explored. The product was transformed into a tricyclic derivative, which can serve as a potential precursor for synthesizing a few alkaloid molecules such as ergot, hapalindole alkaloids, and related heterocyclic compounds. A novel strategy, catalyzed by Rh(III), for synthesizing benzazepinone and azepinone derivatives by using allyl alcohol as a coupling partner has been studied. In this reaction, Rh(III) acts as a catalyst and oxidant. Under the reaction conditions, the allyl alcohol is in-situ converted to its carbonyl compound. The alkylated product obtained in the reaction further undergoes oxidative cyclization in the presence of Lewis acidic AgSbF6. The benzolactum obtained is a valuable intermediate to synthesize berberine-like analog dopamine D3 receptor ligand, which is a potential target in the treatment of neurological disorders.
Indian Institute of Science
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Benzolactum' for particular source types:
Journal articles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography