Academic literature on the topic 'Benzolactum'
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Journal articles on the topic "Benzolactum"
Lam, Hon-Wah, Ka-Yi Man, Wai-Wing Chan, Zhongyuan Zhou, and Wing-Yiu Yu. "Rhodium(iii)-catalyzed formal oxidative [4 + 1] cycloaddition of benzohydroxamic acids and α-diazoesters. A facile synthesis of functionalized benzolactams." Org. Biomol. Chem. 12, no. 24 (2014): 4112–16. http://dx.doi.org/10.1039/c4ob00512k.
Full textDeVita, R. J., and M. J. Wyvratt. "Benzolactam growth hormone secretagogues." Drugs of the Future 21, no. 3 (1996): 273. http://dx.doi.org/10.1358/dof.1996.021.03.353289.
Full textRyu, Ilhyong, Takahide Fukuyama, and Takanobu Bando. "Electron-Transfer-Induced Intramolecular Heck Carbonylation Reactions Leading to Benzolactones and Benzolactams." Synthesis 50, no. 15 (May 29, 2018): 3015–21. http://dx.doi.org/10.1055/s-0037-1609964.
Full textBouillon, J. P., C. Atès, C. Maliverney, Z. Janousek, and H. G. Viehe. "β-TRIFLUOROACETYLATION OF LACTAMS AND BENZOLACTAMS." Organic Preparations and Procedures International 26, no. 2 (April 1994): 249–55. http://dx.doi.org/10.1080/00304949409458029.
Full textKhantikaew, Itsara, Masato Takahashi, Takuya Kumamoto, Noriyuki Suzuki, and Tsutomu Ishikawa. "Synthesis of (−)-benzolactam-V8 by application of asymmetric aziridination." Tetrahedron 68, no. 3 (January 2012): 878–82. http://dx.doi.org/10.1016/j.tet.2011.11.033.
Full textBock, Mark G., Robert M. DiPardo, Daniel F. Veber, Raymond S. L. Chang, Victor J. Lotti, Stephen B. Freedman, and Roger M. Freidinger. "Benzolactams as non-peptide cholecystokinin receptor ligands." Bioorganic & Medicinal Chemistry Letters 3, no. 5 (May 1993): 871–74. http://dx.doi.org/10.1016/s0960-894x(00)80683-6.
Full textMa, Dawei, Guoqiang Wang, Shaomeng Wang, Alan P. Kozikowski, Nancy E. Lewin, and Peter M. Blumberg. "Synthesis and protein kinase C binding activity of benzolactam-V7." Bioorganic & Medicinal Chemistry Letters 9, no. 10 (May 1999): 1371–74. http://dx.doi.org/10.1016/s0960-894x(99)00207-3.
Full textMokrosz, Maria J., Sijka Charakchieva-Minol, and Piotr Kowalski. "Benzolactam Derivatives and Their Affinity for α1- and α2- Adrenoreceptors." Archiv der Pharmazie 334, no. 1 (January 2001): 25–26. http://dx.doi.org/10.1002/1521-4184(200101)334:1<25::aid-ardp25>3.0.co;2-8.
Full textDe Vita, Robert J., Alison J. Frontier, William R. Schoen, Matthew J. Wyvratt, Michael H. Fisher, Kang Cheng, Wanda W. S. Chan, Bridget S. Butler, and Roy G. Smith. "Design and Synthesis of Potent Macrocyclic Benzolactam Growth Hormone Secretagogues." Helvetica Chimica Acta 80, no. 4 (June 30, 1997): 1244–59. http://dx.doi.org/10.1002/hlca.19970800421.
Full textBouillon, Jean-Philippe, Célâl Ates, Zdenek Janousek, and Heinz G. Viehe. "Trifluoromethylated heterocycles from β-trifluoroacetyl-lactams and -benzolactams." Tetrahedron Letters 34, no. 32 (August 1993): 5075–78. http://dx.doi.org/10.1016/s0040-4039(00)60679-2.
Full textDissertations / Theses on the topic "Benzolactum"
López, Muñoz Laura. "Homology modeling and structural analysis of the antipsychotic drugs receptorome." Doctoral thesis, Universitat Pompeu Fabra, 2010. http://hdl.handle.net/10803/7228.
Full textThe study started with obtaining homology models for all the receptors putatively involved in the antipsychotic drugs receptorome, suitable for building consistent drug-receptor complexes. These complexes were structurally analyzed and compared using multivariate statistical methods, which in turn allowed the identification of the relationship between the pharmacological properties of the antipsychotic drugs and the structural differences in the receptor targets. The results can be exploited for the design of safer and more effective antipsychotic drugs with an optimum binding profile.
Tradicionalmente se asumía que los fármacos terapéuticamente efectivos actuaban interaccionando con un único receptor. Actualmente está ampliamente reconocido que el efecto farmacológico de la mayoría de los fármacos es más complejo y abarca a un conjunto de receptores, algunos asociados a los efectos terapéuticos y otros a los secundarios y toxicidad. Los fármacos antipsicóticos son un ejemplo de compuestos eficaces que se caracterizan por unirse a varios receptores simultáneamente (principalmente a receptores unidos a proteína G, GPCR). El trabajo de la presente tesis se ha centrado en el estudio de los mecanismos moleculares que determinan el perfil de afinidad de unión por múltiples receptores de los fármacos antipsicóticos.
En primer lugar se construyeron modelos de homología para todos los receptores potencialmente implicados en la actividad farmacológica de dichos fármacos, usando una metodología adecuada para construir complejos fármaco-receptor consistentes. La estructura de estos complejos fue analizada y se llevó a cabo una comparación mediante métodos estadísticos multivariantes, que permitió la identificación de asociaciones entre la actividad farmacológica de los fármacos antipsicóticos y diferencias estructurales de los receptores diana. Los resultados obtenidos tienen interés para ser explotados en el diseño de fármacos antipsicóticos con un perfil farmacológico óptimo, más seguros y eficaces.
Sherikar, Mahadev. "Construction of C-C bonds by C-H Activation: Rh(III)-Catalyzed reactions of Arenes and Heteroarenes with Maleimides and Allylic Alcohols." Thesis, 2021. https://etd.iisc.ac.in/handle/2005/5227.
Full textIndian Institute of Science