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1

Winterton, Jonathan. The business benefits of competence-based management development. London: H.M.S.O., 1996.

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2

Office, United States Government Accountability. Defense management: DOD needs to demonstrate that performance-based logistics contracts are achieving expected benefits : report to the Subcommittee on Readiness and Management Support, Committee on Armed Services, U.S. Senate. Washington, D.C.]: U.S. Government Accountability Office, 2005.

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3

Taylor, T. M. Secrets to a successful greenhouse business: A complete guideto starting and operating a high-profit business that's benefits the invironment. Melbourne, FL: T.M. Taylor, 1991.

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4

Taylor, T. M. Secrets to a successful greenhouse business: A complete guide to starting & operating a high-profit business that benefits the environment. Melbourne, FL: GreenEarth Publishing Co., 1994.

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M, Taylor T. Secrets to a successful greenhouse and business: A complete guide to starting & operating a high-profit business that benefits the environment. 7th ed. Melbourne, FL: GreenEarth Pub. Co., 1999.

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6

Phillips, Patricia. Data conversion: Calculating the monetary benefits. San Francisco, CA: Pfeiffer, 2008.

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7

M, Taylor T. Secrets to a successful greenhouse and business: A complete guide to starting & operating a high-profit organic or hydroponic business that benefits the environment. 7th ed. Melbourne, FL: GreenEarth Pub. Co., 2000.

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8

Department for Education & Employment. The Business Benefits of Competence-based Management Development. Stationery Office Books, 1996.

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9

Kotwica, Kathleen. Benefits and Security Risks of Web-Based Applications for Business: Trend Report. Elsevier Science & Technology Books, 2013.

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10

Benedek, David M., and Gary H. Wynn. Toward a More Comprehensive Approach to the Management of PTSD. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190205959.003.0016.

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In this volume, after a brief discussion of the phenomenology of posttraumatic stress disorder (PTSD), the current guidelines and clinical consensus surrounding treatment, and the limitations of available treatment supported by sufficient evidence necessary to receive endorsement in practice guidelines, emerging treatments were described that demonstrate varying degrees of promise for relieving the suffering associated with PTSD. Both clinical experience and the most current practice guidelines support the notion that successful treatment requires a partnership between patient and provider, and a concerted effort by the clinician to “meet the patient where he or she is at” in terms of treatment approaches. Therefore, we hope the modalities described in this book encourage creative treatment approaches tailored to individual patient needs and desires based on a mutual understanding of the potential benefits and limitations of available alternatives.
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11

Voinescu, Alexandra, Nadia Wasi Iqbal, and Kevin J. Martin. Management of chronic kidney disease-mineral and bone disorder. Edited by David J. Goldsmith. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0118_update_001.

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In all patients with chronic kidney disease (CKD) stages 3–5, regular monitoring of serum markers of CKD-mineral and bone disorder, including calcium (Ca), phosphorus (P), parathyroid hormone (PTH), 25-hydroxyvitamin D, and alkaline phosphatase, is recommended. Target ranges for these markers are endorsed by guidelines. The principles of therapy for secondary hyperparathyroidism include control of hyperphosphataemia, correction of hypocalcaemia, use of vitamin D sterols, use of calcimimetics, and parathyroidectomy. of hyperphosphataemia is crucial and may be achieved by means of dietary P restriction, use of P binders, and P removal by dialysis. Dietary P restriction requires caution, as it may be associated with protein malnutrition. Aluminium salts are effective P binders, but they are not recommended for long-term use, as Aluminium toxicity (though from contaminated dialysis water rather than oral intake) may cause cognitive impairment, osteomalacia, refractory microcytic anaemia, and myopathy. Ca-based P binders are also quite effective, but should be avoided in patients with hypercalcaemia, vascular calcifications, or persistently low PTH levels. Non-aluminium, non-Ca binders, like sevelamer and lanthanum carbonate, may be more adequate for such patients; however, they are expensive and may have several side effects. Furthermore, comparative trials have failed so far to provide conclusive evidence on the superiority of these newer P binders over Ca-based binders in terms of preventing vascular calcifications, bone abnormalities, and mortality. P removal is about 1800–2700 mg per week with conventional thrice-weekly haemodialysis, but may be increased by using haemodiafiltration or intensified regimens, such as short daily, extended daily or three times weekly nocturnal haemodialysis. Several vitamin D derivatives are currently used for the treatment of secondary hyperparathyroidism. In comparison with the natural form calcitriol, the vitamin D analogue paricalcitol seems to be more fast-acting and less prone to induce hypercalcaemia and hyperphosphataemia, but whether these advantages translate into better clinical outcomes is unknown. Calcimimetics such as cinacalcet can significantly reduce PTH, Ca, and P levels, but they have failed to definitively prove any benefits in terms of mortality and cardiovascular events in dialysis patients. Parathyroidectomy is often indicated in CKD patients with severe persistent hyperparathyroidism, refractory to aggressive medical treatment with vitamin D analogues and/or calcimimetics. This procedure usually leads to rapid improvements in biochemical markers (i.e. significant lowering of serum Ca, P, and PTH) and clinical manifestations (such as pruritus and bone pain); however, the long-term benefits are still unclear.
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12

Cross, Katharine, Katharina Tondera, Anacleto Rizzo, Lisa Andrews, Bernhard Pucher, Darja Istenič, Nathan Karres, and Robert McDonald, eds. Nature-Based Solutions for Wastewater Treatment. IWA Publishing, 2021. http://dx.doi.org/10.2166/9781789062267.

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There are 2.4 billion people without improved sanitation and another 2.1 billion with inadequate sanitation (i.e. wastewater drains directly into surface waters), and despite improvements over the past decades, the unsafe management of fecal waste and wastewater continues to present a major risk to public health and the environment (UN, 2016). There is growing interest in low cost sanitation solutions which harness natural systems. However, it can be difficult for wastewater utility managers to understand under what conditions such nature-based solutions (NBS) might be applicable and how best to combine traditional infrastructure, for example an activated sludge treatment plant, with an NBS such as treatment wetlands. There is increasing scientific evidence that treatment systems with designs inspired by nature are highly efficient treatment technologies. The cost-effective design and implementation of ecosystems in wastewater treatment is something that exists and has the potential to be further promoted globally as both a sustainable and practical solution. This book serves as a compilation of technical references, case examples and guidance for applying nature-based solutions for treatment of domestic wastewater, and enables a wide variety of stakeholders to understand the design parameters, removal efficiencies, costs, co-benefits for both people and nature and trade-offs for consideration in their local context. Examples through case studies are from across the globe and provide practical insights into the variety of potentially applicable solutions. ISBN: 9781789062250 (Paperback) ISBN: 9781789062267 (eBook)
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13

Phillips, Patricia. Data Conversion: Calculating the Monetary Benefits. Center for Creative Leadership, 2008.

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14

Phillips, Patricia. Data Conversion: Calculating the Monetary Benefits. Center for Creative Leadership, 2016.

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15

Mutsaers, Paul, and Marja-Liisa Trux. In Search of the ‘Real’. Edited by Regine Bendl, Inge Bleijenbergh, Elina Henttonen, and Albert J. Mills. Oxford University Press, 2016. http://dx.doi.org/10.1093/oxfordhb/9780199679805.013.10.

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This chapter presents a comparison of two ethnographic case studies in two different national contexts, with the purpose of separating the rhetorics from the realities in the field of diversity management. It counterweighs mainstream diversity management literature by discussing (1) the disadvantages of certain offshoots of diversity management discourses for ethnic minority police officers in the Netherlands and (2) the benefits of the absence of diversity management for software engineers working in a highly internationalized high-tech company in Finland, a company characterized by a strong tradition of ‘organizational democracy’. The two studies are based on long-term fieldwork in both organizational settings, including several years of participant observation.
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16

Wilkinson, Philip. Cognitive behaviour therapy. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199644957.003.0017.

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Cognitive behaviour therapy (CBT) is a dominant psychological treatment in the management of a range of psychiatric disorders and is increasingly being refined to suit the needs older adults. This chapter summarises the theory and practice of CBT, with an emphasis on assessment, formulation, and adaptation of treatment with older patients. Management of depressive disorder, anxiety disorders and dementia caregiver distress are described in detail with relevant case examples. Problem-solving therapy and behavioural activation are described. Mindfulness-based cognitive therapy (MBCT) has potential benefits in the treatment of older adults. MBCT is described and applications with older people are reviewed. Newer applications are outlined, including treatment of psychological symptoms associated with physical illness, psychosis and memory impairment. The evidence base for CBT-based interventions with older adults is limited; the limitations and extent of the current evidence are reviewed.
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17

Taylor, T. M. Secrets to a Successful Greenhouse and Business: A Complete Guide to Starting and Operating a High-Profit Organic or Hydroponic Business That Benefits the Environment. 2nd ed. Greenearth Pub Co, 2007.

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18

Phillips, Patricia. Data Conversion: Calculating the Monetary Benefits (Measurement in Action). Pfeiffer, 2008.

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19

Giannuzzi, Pantaleo. General remarks. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656653.003.0020.

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Cardiac patients should be advised about and have the opportunity to access a comprehensive cardiovascular prevention and rehabilitation programme, addressing all aspects of lifestyle—smoking cessation, healthy eating, and being physically active—together with more effective management of blood pressure, lipids, and glucose. To achieve the clinical benefits of a multidisciplinary and multifactorial prevention programme we need to integrate professional lifestyle interventions with effective risk factor management and evidence-based drug therapies, appropriately adapted to the medical, cultural, and economic setting of a country. The challenge is to engage and motivate cardiologists, physicians, and health professionals to routinely practise high-quality preventive cardiology and promote a healthcare system which invests in prevention.
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20

Wagg, Adrian. Incontinence, the sleeping geriatric giant: challenges and solutions. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199689644.003.0008.

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Key points• The prevalence of urinary incontinence increases in association with increasing age.• Behavioural and lifestyle interventions, including exercise, are effective in older people.• There is an increasing evidence base for pharmacological therapy of urgency incontinence in the elderly and frail elderly.• Surgical management for older men and women is associated with benefit but should be performed with due regard to potential benefits and harms, remaining life expectancy, and the expectations of both patient and, where relevant, caregiver.• Continence care should be based around provision by specialist nurse practitioners working within a multiprofessional, integrated service.
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21

Ruskin, Keith J., Marjorie P. Stiegler, and Stanley H. Rosenbaum, eds. Quality and Safety in Anesthesia and Perioperative Care. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199366149.001.0001.

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Quality and Safety in Anesthesia and Perioperative Care offers practical suggestions for improving both quality of care and patient safety in the perioperative setting. The book is divided into two parts: the first on clinical foundations and the second on practical applications, and the chapters emphasize strategies that support reform at all levels, from operating room practices to institutional procedures. Written by leading experts in their fields, chapters are based on accepted safety, human performance, and quality management science, and they illustrate the benefits of collaboration between medical professionals and human factors experts. The book highlights concepts such as situation awareness, staff resource management, threat and error management, checklists, explicit practices for monitoring, and safety culture. Quality and Safety in Anesthesia and Perioperative Care is a must-have resource for those preparing for the quality and safety questions on the American Board of Anesthesiology certification examinations, as well as clinicians and trainees in all practice settings.
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22

Moran, John. Tropical Dairy Farming. CSIRO Publishing, 2005. http://dx.doi.org/10.1071/9780643093133.

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Tropical Dairy Farming is a manual designed for use by dairy production advisors working in tropical areas, especially in South-East Asia. It aims to increase the productivity of small holder dairy farmers in the humid tropics by improving the feeding management of their livestock. It shows how to provide dairy cows with cost-effective feeds that match small holder farming systems and discusses the major obstacles to improving feeding management in the humid tropics. The author shows the benefits and drawbacks of various feed components and the calculation of balanced diets based mainly on forages combined with some supplementary feeding. Diseases and problems associated with unbalanced diets are also covered, as well as important information on growing and conserving quality forages as silage. The book draws on examples from a variety of countries including Indonesia, Malaysia, Thailand, Vietnam, China, East Timor and the Philippines.
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23

Zabrecky, George. The Role of Chiropractic in Mind–Body Health. Edited by Anthony J. Bazzan and Daniel A. Monti. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190690557.003.0009.

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The chiropractic approach is based on the principles that diseases, both psychiatric and medical, are caused by disturbances in the nervous system and that such disturbances are often related to musculoskeletal problems. Thus chiropractic therapies utilize an integrative approach to health and well-being that includes various spinal manipulations as well as an integrative approach to the patient. Chiropractic therapies are most well known for the management of chronic and acute pain, which frequently can be accompanied by anxiety and depression symptoms. There is little direct evidence that chiropractic care improves mental health outside of the benefits related to pain alleviation. However, based on the overall chiropractic model, chiropractic therapy can potentially benefit a wide variety of psychological symptoms, but more research is needed. This chapter reviews the principles of chiropractic care, particularly in the context of psychiatric conditions, and provides information for future clinical and research programs.
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24

Mughal, Tariq I., and Tiziano Barbui, eds. Oxford Specialist Handbook: Myeloproliferative Neoplasms. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198744214.001.0001.

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Our understanding of myeloproliferative neoplasms (MPN) disorders, a group of clonal haematological malignancies characterized by excessive accumulation of one or more myeloid cell lineages, has grown considerably over the past four decades. Even more importantly is the speed at which many of these findings were translated to accord survival benefits to our patients with MPN, in particular chronic myeloid leukaemia (CML), polycythaemia vera (PV), essential thrombocythaemia (ET), and primary myelofibrosis (PMF). This text offers a detailed evidence-based guide to MPN in an easily accessible format, structure to facilitate learning specialist information presenting core information in ‘bite size’ chunks. Each chapter summarizes the state-of-the art preclinical and clinical knowledge, and its impact on the clinical management of patients with MPN.
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25

Williams, Erin S., Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi Aina, eds. Clinical Pediatric Anesthesia. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.001.0001.

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Clinical Pediatric Anesthesia: A Case-Based Handbook presents the reader with a very wide variety of clinical scenarios regarding the perioperative management of pediatric patients. It is divided into 15 sections and covers the field of pediatric anesthesiology with a point-of-care approach. This textbook has over 50 contributors who are pediatric anesthesiologists at tertiary children’s hospitals, thus giving the reader multiple approaches to the anesthetic care of the pediatric patient. The clinician can use the discussion section as an opportunity to review various options as well as the advantages and disadvantages of different aspects of the perioperative management of the pediatric patient. Given the many benefits of self-directed and simulation-based learning, the reader is presented with an “Introduction” to the subject, followed by “Learning Objectives” to master after reading the section. By placing the reader in a variety of clinical scenarios, the clinician can think through the management of such vignettes with the “Discussion” section that is written in a “question and answer” format. Each chapter ends with the highest yield, and most salient information presented in the “Summary”. “Annotated References,” “Bibliography,” and “Further Reading” allow the reader to explore the literature pertaining to the topic. Overall, the variety of cases presented along with the expertise of the contributors renders valuable real-life clinical situations that promote critical thinking and evaluation necessary for all pediatric anesthesiology consultants.
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26

Barthel, Andreas, and Michael Bauer. Psychotropic drugs and metabolic risk. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198789284.003.0011.

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Increased appetite and weight gain represent a significant problem related with particular antipsychotic drugs, antidepressants, mood stabilizers, and—to a lesser extent—anxiolytic drugs. Psychotropic drug-induced weight gain may contribute to obesity-related metabolic changes and pathological conditions such as dyslipidaemia, type-2-diabetes and hypertension—summarized as the metabolic syndrome—with an increased risk for cardiovascular morbidity and mortality. Interestingly, psychotropic drugs are also used for the treatment of diabetes-related complications. For example, antidepressants are effective for the treatment of neuropathic pain in patients with diabetic neuropathy. Therefore, it is essential to thoroughly balance potential benefits and risks in an individual patient to ensure drug safety and optimize the clinical outcome. In addition to diet and exercise, selection of psychotropic drugs and dose adjustment based on regular clinical follow-up visits is the key for the prevention and management of psychotropic drug induced weight gain in clinical practice.
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27

Bohr, Yvonne, Cindy H. Liu, Stephen H. Chen, and Leslie K. Wang. Satellite Babies. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190265076.003.0015.

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Every year, in North American immigrant communities, thousands of infants experience separations from their parents when left or sent to live with extended family overseas. The practice of transnational, temporary boarding is widespread and poorly understood. This practice has been documented in North American Chinese, South Asian, Caribbean, and Filipino communities. This custom has raised concerns among child developmentalists and clinicians about potentially harmful consequences to children and parents. However, such separations may be misunderstood and prone to unnecessary stigma based on a lack of cultural appreciation. This chapter examines motives for and repercussions of separating parents and infants for extensive periods of time. The authors contextualize their analysis within a framework of stress management during the process of settlement and acculturation and consider the protective benefits of cultural values and practices in addition to risks. They use the Chinese immigrant community as an exemplar for the proposed framework.
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28

Fawcett, William J. Anaesthesia for abdominal surgery. Edited by Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0061.

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Care of patients undergoing major gastrointestinal surgery has been revolutionized in the last decade. The widespread adoption of laparoscopic surgery has bought benefits but also new challenges. Anaesthetic techniques, particularly refinements in analgesic regimens and fluid management, have also brought benefits to patients. However, many more elderly and frail patients are undergoing major surgery which is a challenge in both expertise and resources. Anaesthesia for patients undergoing gastrointestinal surgery has evolved into a package of perioperative care, with the anaesthetist increasingly viewed as the perioperative physician. Anaesthetists are now involved not only within the operating theatre, but with assessing risk for patients, optimizing them prior to surgery, and supervising postoperative care and in particular early recognition and treatment of complications. Liver surgery has become routine for patients particularly with secondary colorectal metastases. Previously, 5-year survival was very rare in these groups of patients, but now approximately half of patients are alive at 5 years. Colorectal surgery has also been transformed and the enhanced recovery programme has typified the way in which many years of dogma have been challenged, to be replaced by evidence-based pathways. Overall, for major elective surgery, results have improved and in general, morbidity, mortality, complications, and length of hospital stay for patients have reduced. For emergency patients, although there have been improvements too, there is still widespread concern about high mortality and marked variation in care between centres.
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29

Connellan, Geoff. Water Use Efficiency for Irrigated Turf and Landscape. CSIRO Publishing, 2013. http://dx.doi.org/10.1071/9780643106888.

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Achieving high water use efficiency in maintaining turf, trees and landscape areas is a core responsibility of open space managers. Water Use Efficiency for Irrigated Turf and Landscape provides a logical and scientifically sound approach to irrigation in urban areas in Australia. It is based on green space delivering defined outcomes using the principles of water sensitive urban design and irrigation efficiency. The book covers all stages of the water pathway – from the source to delivery into the plant root zone. Major topics include system planning, estimating water demand, water quality, irrigation systems, soil management and irrigation performance evaluation. Clearly presented explanations are included, as well as line drawings and worked examples, and a plant water use database covering more than 250 plant species. A Water Management Planning template is included to guide water managers and operators through a process that will deliver a sound plan to achieve sustainable turf, urban trees and landscapes. Best Management Practice Irrigation principles are outlined and their implementation in open space turf and landscape situations is explained. The benefits and limitations of the various methods of delivering water to plants are covered, together with case studies and guidelines for specific horticultural situations. Methodologies to evaluate irrigated sites are included along with recommended benchmark values. The book presents the latest irrigation technology, including developments in water application, control technology and environmental sensors such as weather stations, soil moisture sensors and rain sensors.
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30

Thompson, Jonathan P. Anaesthesia for vascular surgery. Edited by Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0058.

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Vascular surgical patients are at higher risk of cardiovascular morbidity and mortality than other surgical patients, and perioperative care remains challenging. However, vascular surgical practice is changing, with the expanding use of endovascular techniques to treat patients with vascular disease, improvements in medical therapy, and the evolution of evidence-based approaches to preoperative assessment. Preoperative assessment should concentrate on identifying and optimizing potentially correctable medical conditions, in particular cardiovascular disease. Successful outcomes depend on good anaesthetic techniques with emphasis on meticulous attention to detail and maintaining cardiovascular function and stability. Good communication with surgical and radiological colleagues is also vital. Anaesthesia for major vascular surgery also requires expertise in managing major haemorrhage, the use of invasive monitoring and cardioactive drugs, and regional anaesthesia. Knowledge and skills in the use of specific techniques for monitoring and protection against organ dysfunction are required. Endovascular surgery may be performed in dedicated operating suites or within the radiology department so the anaesthetist needs to be aware of considerations for anaesthesia in an isolated environment. This chapter details the management of patients presenting for the commonest major vascular procedures. All aspects of perioperative care for patients with abdominal and thoracic aortic aneurysms, occlusive aortic and peripheral vascular disease, and carotid stenosis are discussed. Anaesthesia for open surgery, endovascular and hybrid procedures, and elective and emergency procedures are included. The benefits of regional and general anaesthetic techniques are considered, where appropriate. The chapter also incorporates the anaesthetic management for less common procedures to treat carotid body tumours, thoracic outlet syndrome, and for thoracoscopic sympathectomy.
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31

Jardine, Alan G., and Rajan K. Patel. Lipid disorders of patients with chronic kidney disease. Edited by David J. Goldsmith. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0102.

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The risk of developing cardiovascular (CV) disease is increased in patients with chronic kidney disease (CKD) and although dyslipidaemia is a major contributory factor to the development of premature CV disease, the relationship is complex. Changes in lipid fractions are related to glomerular filtration rate and the presence and severity of proteinuria, diabetes, and other confounding factors. The spectrum of CV disease changes from lipid-dependent, atheromatous coronary disease in early CKD to lipid-independent, non-coronary disease, manifesting as heart failure, and sudden cardiac death in advanced and end-stage renal disease. Statin-based lipid-lowering therapy is proven to reduce coronary events across the spectrum of CKD. The relative reduction in overall CV events, however, diminishes as CKD progresses and the proportion of lipid-dependent coronary events declines. There is nevertheless a strong argument for the use of statin-based therapy across the spectrum of CKD. The argument is particularly strong for those patients with progressive renal disease who will eventually require transplantation, in whom preventive therapy should start as early as possible. The SHARP study established the benefits and endorses the use of lipid-lowering therapy in CKD 3-4 but uncertainty about the value of initiation of statin therapy in CKD 5 remains. There is, however, no rationale for stopping agents started earlier in the course of the illness for compelling indications, particularly in those who will ultimately be transplanted. The place of high-density lipoprotein-cholesterol raising and triglyceride lowering therapy needs to be assessed in trials. Modifying dyslipidaemia in CKD has demonstrated that lipid-dependent atheromatous cardiovascular disease is only one component of the burden of CV disease in CKD patients, that this is proportionately less in advanced CKD, and that modification of lipid profiles is only one part of CV risk management.
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32

Ponti, Cesare, Paola Schwizer, Floricel Rugiero, Riccardo Bua Odetti, Giacomo Guerrini, Jennifer Hoffman, and et alia. Governance e strategia per la gestione dei rischi nelle imprese non finanziarie. AIFIRM, 2020. http://dx.doi.org/10.47473/2016ppa00024.

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The “Corporate Risk Governance & Control” Commission, composed of risk managers, working for the top leading companies and financial institutions, many of which are publicly listed, as well as academics and board members, worked together to produce a position paper that aspires to provide principles and best practices regarding strategic risk management and risk governance. In particular, the document provides a framework, applicable to non financial companies based on their specific profiles, that integrates the general requirements established by the standard setters (i.e. the Code of Corporate Governance for publicly listed companies, the COSO Framework 2017, ISO 31000:2018 and banking and financial sector regulations) while taking into consideration elements of differentiation, uniqueness and different organizational and managerial approaches to affront risk The document is composed of two main sections: "Risk Governance” and “Risk & Strategy". In the first section, roles and responsibilities regarding risk management are addressed, starting from the importance to diffuse a risk culture consistent with mission, vision and company values to outlining the benefits of adequate organizational principals and governance. Once clarifying the difference between the first, second and third level of defense, the section concludes with a detailed analysis dedicated to the role of the Chief Risk Officer, in which the requirements of professionalism and independence are underlined as well as the key role played in the consolidation of a holistic view of the risk profile within the organization. In the second section of the position paper, ample space is dedicated to the Risk Appetite Framework, a fundamental tool to connect the business strategy and punctual risk quantification. The objective is to offer guidelines to define the risk appetite within a company. The final section of the paper proposes some suggestions for risk classification considering a portfolio view, as well as ulterior reflections regarding risk quantification, highlighting also some of the principle approaches to targeted evaluations and the drafting of a strategic plan pondered around risk.
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33

Cassidy, Jim, Donald Bissett, Roy A. J. Spence OBE, Miranda Payne, Gareth Morris-Stiff, and Madhumita Bhattacharyya. Breast cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199689842.003.0014_update_001.

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Thoracic cancer examines the epidemiology, aetiology, and role of screening and prevention in the reduction of deaths from lung cancer, the majority caused by cigarette smoking. The pathology and genetics of lung cancer, with particular note of the driver mutations, are followed by the symptoms and signs of the disease. Appropriate investigations are described to stage the tumour. The optimum treatment for localised non-small cell lung cancer (NSCLC) is surgical resection, followed in some cases by adjuvant chemotherapy. However, most cases present with disease too advanced for surgery, and for these chemotherapy and radiotherapy are appropriate. Metastatic NSCLC can be treated with platinum based doublet chemotherapy with modest palliative benefits. Metastatic NSCLC with specific driver mutations are amenable to control by targeted therapy. Locally advanced NSCLC is often treated with similar chemotherapy and radiotherapy, ideally administered concurrently, to achieve symptom relief but also improved survival rates. Short course simple radiotherapy offers symptom relief in patients not fit for chemotherapy. Patients with localised NSCLC who are not fit for surgery, may benefit from radical radiotherapy, particularly stereotactic radiotherapy. Small cell lung cancer (SCLC) is characterised by almost universal systemic spread, so that surgery is rarely appropriate. Staging is similar to NSCLC, and chemotherapy is the mainstay of treatment, usually cisplatin or carboplatin combined with etoposide. When possible, this is combined with concurrent thoracic irradiation covering all radiological sites of disease. Prophylactic cranial irradiation reduces the risk of CNS disease. Malignant pleural mesothelioma is caused by occupational asbestos exposure. Symptoms and signs, investigation and staging, and management are discussed. Thymic tumours, their pathology, presenting symptoms including paraneoplastic syndromes, investigation, staging and treatment are reviewed.
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34

Santibañez Gruber, Rosa Maria, and Antonia Caro González, eds. DEUSTO Social Impact Briefings No. 4 (2019). University of Deusto, 2020. http://dx.doi.org/10.18543/dsib-4(2020).

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This fourth edition of the DSIB presents the main results of the research carried out under four broad-based projects jointly developed by researchers and actors involved in topics of great social relevance such as responsible gambling, Cooperative-Intelligent transport Systems, gender dimension of alcohol addiction and support and care for victims of trafficking for sexual exploitation. This issue comprises the following four briefings: 1. What would sports betting advertising be like if it were handled more responsibly? will analyse the structure of sports betting advertising, in an attempt to understand whether such advertising could become a public health issue. This briefing examines different works that have led to scientific publications and presents their main conclusions as well as the major recommendations for gambling companies and regulators. 2. How can artificial intelligence reduce road traffic accidents and prevent congestion? This briefing seeks to present the benefits of the TIMON system for optimising traffic management and urban transport network operations in cities, directly supporting transport managers in their decision-making processes for transport operations. 3. Gender inequalities in matters of drug addiction: how does alcoholism really affect women? aims to study the phenomenon of drug dependence from a gender perspective. This involves identifying what kind of socio-cultural and psychological representations are involved in women, according to their gender role, so that they develop a series of risk factors for them, both for the beginning of consumption and in its continuity. In addition, the research team proposes guidelines for a specialized care for women in this area, in order to increase the effectiveness of required interventions. 4. Key points for supporting and accompanying victims and survivors of human trafficking for sexual exploitation is intended as a working document for specialists involved in the prevention and detection of cases and in support and care for victims. It seeks to fill the current gaps and meet the needs of women victims of trafficking providing a better response to their situations.
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35

Medicaid: Three states' experiences in buying employer-based health insurance : report to the chairman, Committee on Commerce, House of Representatives. Washington, D.C: The Office, 1997.

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36

Office, General Accounting. Medicaid: Three states' experiences in buying employer-based health insurance : report to the Chairman, Committee on Commerce, House of Representatives. Washington, D.C: The Office, 1997.

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37

Office, General Accounting. Medicaid: Three states' experiences in buying employer-based health insurance : report to the chairman, Committee on Commerce, House of Representatives. Washington, D.C: The Office, 1997.

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